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Ernst Wagner

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Kerstin Knoop; Peter J Nelson; Nathalie Schwenk; Ernst Wagner; Michael J Willhauck; Christian Zach; Christoph Zischek; Patrick Dolp; Burkhard Göke; Markus Hacker; Christine Spitzweg
Stromal targeting of sodium iodide symporter using mesenchymal stem cells allows enhanced imaging and therapy of hepatocellular carcinoma.
Matthäus Noga; Joachim P Spatz; Ernst Wagner; Seraphine V Wegner; Gerhard Winter; Daniel Edinger; Raphaela Kläger; Ahmed Besheer
The effect of molar mass and degree of hydroxyethylation on the controlled shielding and deshielding of hydroxyethyl starch-coated polyplexes.
Alexandra Vetter; Kulpreet S Virdi; Ernst Wagner; Wolfgang Rödl; Christina Scheu; Christine Spitzweg; Sigrid Espenlaub; Per S Holm; Florian Kreppel; Manfred Ogris
Adenoviral vectors coated with PAMAM dendrimer conjugates allow CAR independent virus uptake and targeting to the EGF receptor.

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2013: Kerstin Knoop; Peter J Nelson; Nathalie Schwenk; Ernst Wagner; Michael J Willhauck; Christian Zach; Christoph Zischek; Patrick Dolp; Burkhard Göke; Markus Hacker; Christine Spitzweg
Stromal targeting of sodium iodide symporter using mesenchymal stem cells allows enhanced imaging and therapy of hepatocellular carcinoma.
Human gene therapy 2013;24(3):306-16.
2013: Matthäus Noga; Joachim P Spatz; Ernst Wagner; Seraphine V Wegner; Gerhard Winter; Daniel Edinger; Raphaela Kläger; Ahmed Besheer
The effect of molar mass and degree of hydroxyethylation on the controlled shielding and deshielding of hydroxyethyl starch-coated polyplexes.
Biomaterials 2013;34(10):2530-8.
2013: Alexandra Vetter; Kulpreet S Virdi; Ernst Wagner; Wolfgang Rödl; Christina Scheu; Christine Spitzweg; Sigrid Espenlaub; Per S Holm; Florian Kreppel; Manfred Ogris
Adenoviral vectors coated with PAMAM dendrimer conjugates allow CAR independent virus uptake and targeting to the EGF receptor.
Molecular pharmaceutics 2013;10(2):606-18.
2013: Rebekka Kubisch; Lilja Meissner; Andreas Roidl; Helmut Blum; Michael Günther; Stefan Krebs; Ernst Wagner
A Comprehensive Gene Expression Analysis of Resistance Formation upon Metronomic Cyclophosphamide Therapy.
Translational oncology 2013;6(1):1-9.
2013: Baowei Su; Joana R Viola; Ernst Wagner; Martina Anton; Arzu Cengizeroglu; Joachim W Ellwart; Katarina Farkasova; Rudolf Haase; Manfred Ogris
Systemic TNFα gene therapy synergizes with liposomal doxorubicine in the treatment of metastatic cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2013;21(2):300-8.
2013: Christina Troiber; Daniel Edinger; Annika Herrmann; Raphaela Kläger; Petra Kos; Laura Schreiner; Ernst Wagner
Stabilizing effect of tyrosine trimers on pDNA and siRNA polyplexes.
Biomaterials 2013;34(5):1624-33.
2013: Joana R Viola; Ernst Wagner; Robert Besch; Diana F Rafael; Manfred Ogris
Gene therapy for advanced melanoma: selective targeting and therapeutic nucleic acids.
Journal of drug delivery 2013;2013():897348.
2013: Christian Marfels; Ernst Wagner; Miriam Hoehn; Michael Günther
Characterization of in vivo chemoresistant human hepatocellular carcinoma cells with transendothelial differentiation capacities.
BMC cancer 2013;13():176.
2013: Wolfgang Rödl; David Schaffert; Ernst Wagner; Manfred Ogris
Synthesis of polyethylenimine-based nanocarriers for systemic tumor targeting of nucleic acids.
Methods in molecular biology (Clifton, N.J.) 2013;948():105-20.
2012: Eveline E Salcher; Max Scheible; Naresh Badgujar; Thomas Fröhlich; Petra Kos; Ernst Wagner
Sequence-defined four-arm oligo(ethanamino)amides for pDNA and siRNA delivery: Impact of building blocks on efficacy.
Journal of controlled release : official journal of the Controlled Release Society 2012;164(3):380-6.
2012: Thomas Fröhlich; Verena Russ; Daniel Edinger; Ernst Wagner
Stabilization of polyplexes via polymer crosslinking for efficient siRNA delivery.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012;47(5):914-20.
2012: Prajakta S Oak; Ulf R Rapp; Joachim W Ellwart; Pjotr Knyazev; Florian Kopp; Chitra Thakur; Axel Ullrich; Ernst Wagner; Andreas Roidl
Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells.
International journal of cancer. Journal international du cancer 2012;131(12):2808-19.
2012: Romina M Wiedmann; Stefan Zahler; Karin von Schwarzenberg; Ernst Wagner; Rebekka Kubisch; Johanna Liebl; Rolf Müller; Andrea Palamidessi; Christina Schempp; Laura Schreiner; Giorgio Scita; Dirk Trauner; Gyorgy Vereb; Angelika M Vollmar
The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1.
Cancer research 2012;72(22):5976-87.
2012: S Rath; L Schreiner; A Ullrich; Ernst Wagner; Robert Fürst; M Günther; J Herrmann; Uli Kazmaier; J Liebl; Rolf Müller; J L Burkhart; Angelika M Vollmar; Stefan Zahler
Anti-angiogenic effects of the tubulysin precursor pretubulysin and of simplified pretubulysin derivatives.
British journal of pharmacology 2012;167(5):1048-61.
2012: Claudia Scholz; Ernst Wagner
Therapeutic plasmid DNA versus siRNA delivery: common and different tasks for synthetic carriers.
Journal of controlled release : official journal of the Controlled Release Society 2012;161(2):554-65.
2012: Ernst Wagner
Polymers for siRNA delivery: inspired by viruses to be targeted, dynamic, and precise.
Accounts of chemical research 2012;45(7):1005-13.
2012: Frauke M Mickler; Leonhard Möckl; Manfred Ogris; Nadia Ruthardt; Ernst Wagner; Christoph Bräuchle
Tuning nanoparticle uptake: live-cell imaging reveals two distinct endocytosis mechanisms mediated by natural and artificial EGFR targeting ligand.
Nano letters 2012;12(7):3417-23.
2012: Thomas Fröhlich; Philipp Hadwiger; Raphaela Kläger; Irene Martin; Edith Salcher; David Schaffert; Christina Troiber; Hans-Peter Vornlocher; Naresh Badgujar; Arzu Cengizeroglu; Daniel Edinger; Ernst Wagner
Structure-activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides.
Journal of controlled release : official journal of the Controlled Release Society 2012;160(3):532-41.
2012: Christian Dohmen; Daniel Edinger; Thomas Fröhlich; Philipp Hadwiger; Ulrich Lächelt; Joachim Rädler; Laura Schreiner; Christina Troiber; Hans-Peter Vornlocher; Ernst Wagner
Nanosized multifunctional polyplexes for receptor-mediated siRNA delivery.
ACS nano 2012;6(6):5198-208.
2012: Kevin Maier; Ernst Wagner
Acid-labile traceless click linker for protein transduction.
Journal of the American Chemical Society 2012;134(24):10169-73.
2012: Irene Martin; Carlos Mas-Moruno; David Schaffert; Meritxell Teixidó; Christina Troiber; Christian Dohmen; Ernest Giralt; Michael Günther; Horst Kessler; Petra Kos; Ulrich Lächelt; Ernst Wagner
Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery.
Organic & biomolecular chemistry 2012;10(16):3258-68.
2012: Matthäus Noga; Wolfgang Rödl; Ernst Wagner; Gerhard Winter; Daniel Edinger; Ahmed Besheer
Controlled shielding and deshielding of gene delivery polyplexes using hydroxyethyl starch (HES) and alpha-amylase.
Journal of controlled release : official journal of the Controlled Release Society 2012;159(1):92-103.
2012: Galith Abourbeh; Eyal Mishani; Manfred Ogris; Wolfgang Rödl; Alexei Shir; Ernst Wagner; Alexander Levitzki
PolyIC GE11 polyplex inhibits EGFR-overexpressing tumors.
IUBMB life 2012;64(4):324-30.
2012: Manfred Ogris; Ernst Wagner
Synthesis of linear polyethylenimine and use in transfection.
Cold Spring Harbor protocols 2012;2012(2):246-50.
2012: Christian Dohmen; Thomas Fröhlich; Philipp Hadwiger; Ulrich Lächelt; Ingo Röhl; Hans-Peter Vornlocher; Ernst Wagner
Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing.
Molecular therapy. Nucleic acids 2012;1():e7.
2012: Florian Kopp; Prajakta S Oak; Ernst Wagner; Andreas Roidl
miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression.
PloS one 2012;7(11):e50469.
2011: Kathrin Klutz; Sibylle Ziegler; Ernst Wagner; Michael J Willhauck; Kerstin Knoop; Manfred Ogris; Franz-Josef Gildehaus; Sebastian Fürst; Nathalie Wunderlich; Christian Zach; Christian Dohmen; Burkhard Göke; Reingard Senekowitsch-Schmidtke; Christine Spitzweg
Image-guided tumor-selective radioiodine therapy of liver cancer after systemic nonviral delivery of the sodium iodide symporter gene.
Human gene therapy 2011;22(12):1563-74.
2011: A Schäfer; W M van Weerden; W Rödl; D Schaffert; R Kraaij; Ernst Wagner; A Vetter; A Pahnke; C M A de Ridder; C Spitzweg; Manfred Ogris
Disconnecting the yin and yang relation of epidermal growth factor receptor (EGFR)-mediated delivery: a fully synthetic, EGFR-targeted gene transfer system avoiding receptor activation.
Human gene therapy 2011;22(12):1463-73.
2011: Alexei Shir; Ernst Wagner; Shoshana Klein; Alexander Levitzki; Manfred Ogris
Nucleic acid-based therapeutics for glioblastoma.
Anti-cancer agents in medicinal chemistry 2011;11(8):693-9.
2011: Christina Troiber; Ernst Wagner
Nucleic acid carriers based on precise polymer conjugates.
Bioconjugate chemistry 2011;22(9):1737-52.
2011: David Schaffert; Silke Seeber; Christina Troiber; Naresh Badgujar; Christian Dohmen; Daniel Edinger; Katarina Farkasova; Thomas Fröhlich; Philipp Hadwiger; Kerstin Jahn-Hofmann; Raphaela Kläger; G Maiwald; Irene Martin; Eveline E Salcher; Ernst Wagner
Solid-phase synthesis of sequence-defined T-, i-, and U-shape polymers for pDNA and siRNA delivery.
Angewandte Chemie (International ed. in English) 2011;50(38):8986-9.
2011: Kerstin Knoop; Marie Kolokythas; Peter J Nelson; Guido Böning; Dan Draganovici; Franz-Josef Gildehaus; Burkhard Göke; Kathrin Klutz; Ernst Wagner; Michael J Willhauck; Nathalie Wunderlich; Christian Zach; Christine Spitzweg
Image-guided, tumor stroma-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated NIS gene delivery.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(9):1704-13.
2011: Axel Schlossbauer; Ernst Wagner; Christian Dohmen; David Schaffert; Thomas Bein
pH-responsive release of acetal-linked melittin from SBA-15 mesoporous silica.
Angewandte Chemie (International ed. in English) 2011;50(30):6828-30.
2011: Terese Magnusson; Martin Schleef; Ernst Wagner; Rudolf Haase; Manfred Ogris
Sustained, high transgene expression in liver with plasmid vectors using optimized promoter-enhancer combinations.
The journal of gene medicine 2011;13(7-8):382-91.
2011: Manfred Ogris; Ernst Wagner
To be targeted: is the magic bullet concept a viable option for synthetic nucleic acid therapeutics?
Human gene therapy 2011;22(7):799-807.
2011: Haijun Yu; Christian Dohmen; Yunqiu Li; Yu Nie; Ernst Wagner
Epidermal growth factor-PEG functionalized PAMAM-pentaethylenehexamine dendron for targeted gene delivery produced by click chemistry.
Biomacromolecules 2011;12(6):2039-47.
2011: Yu Nie; Manfred Ogris; Wolfgang Rödl; David Schaffert; Ernst Wagner; Michael Günther
Dual-targeted polyplexes: one step towards a synthetic virus for cancer gene therapy.
Journal of controlled release : official journal of the Controlled Release Society 2011;152(1):127-34.
2011: Julia Christina Kasper; David Schaffert; Manfred Ogris; Ernst Wagner; Wolfgang Friess
Development of a lyophilized plasmid/LPEI polyplex formulation with long-term stability--A step closer from promising technology to application.
Journal of controlled release : official journal of the Controlled Release Society 2011;151(3):246-55.
2011: David Schaffert; Naresh Badgujar; Ernst Wagner
Novel Fmoc-polyamino acids for solid-phase synthesis of defined polyamidoamines.
Organic letters 2011;13(7):1586-9.
2011: Kathrin Klutz; David Schaffert; Michael J Willhauck; Geoffrey K Grünwald; Rudolf Haase; Nathalie Wunderlich; Christian Zach; Franz-Josef Gildehaus; Reingard Senekowitsch-Schmidtke; Burkhard Göke; Ernst Wagner; Manfred Ogris; Christine Spitzweg
Epidermal growth factor receptor-targeted (131)I-therapy of liver cancer following systemic delivery of the sodium iodide symporter gene.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(4):676-85.
2011: David Schaffert; Melinda Kiss; Wolfgang Rödl; Alexei Shir; Alexander Levitzki; Manfred Ogris; Ernst Wagner
Poly(I:C)-mediated tumor growth suppression in EGF-receptor overexpressing tumors using EGF-polyethylene glycol-linear polyethylenimine as carrier.
Pharmaceutical research 2011;28(4):731-41.
2011: Alexei Shir; Manfred Ogris; Wolfgang Roedl; Ernst Wagner; Alexander Levitzki
EGFR-homing dsRNA activates cancer-targeted immune response and eliminates disseminated EGFR-overexpressing tumors in mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(5):1033-43.
2011: Philipp Dussmann; Terese Magnusson; Manfred Ogris; Judith I Pagel; Wolfgang Schaper; Sabina Vogel; Ernst Wagner; Rene Zimmermann; Elisabeth Deindl
Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing.
BMC developmental biology 2011;11():28.
2011: Julia Christina Kasper; David Schaffert; Manfred Ogris; Ernst Wagner; Wolfgang Friess
The establishment of an up-scaled micro-mixer method allows the standardized and reproducible preparation of well-defined plasmid/LPEI polyplexes.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2011;77(1):182-5.
2011: Christian Dohmen; Ernst Wagner
Multifunctional CPP polymer system for tumor-targeted pDNA and siRNA delivery.
Methods in molecular biology (Clifton, N.J.) 2011;683():453-63.
2011: Yu Nie; Michael Günther; Zhongwei Gu; Ernst Wagner
Pyridylhydrazone-based PEGylation for pH-reversible lipopolyplex shielding.
Biomaterials 2011;32(3):858-69.
2011: Daniel Edinger; Ernst Wagner
Bioresponsive polymers for the delivery of therapeutic nucleic acids.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2011;3(1):33-46.
2010: Sina Rupprecht; Claudia Hagedorn; Davide Seruggia; Terese Magnusson; Ernst Wagner; Manfred Ogris; Hans J Lipps
Controlled removal of a nonviral episomal vector from transfected cells.
Gene 2010;466(1-2):36-42.
2010: Reza Oskuee; Alexander Philipp; Ali Dehshahri; Ernst Wagner; Mohammad Ramezani
The impact of carboxyalkylation of branched polyethylenimine on effectiveness in small interfering RNA delivery.
The journal of gene medicine 2010;12(9):729-38.
2010: Sigrid Espenlaub; Stephanie Corjon; Tatjana Engler; Carolin Fella; Manfred Ogris; Ernst Wagner; Stefan Kochanek; Florian Kreppel
Capsomer-specific fluorescent labeling of adenoviral vector particles allows for detailed analysis of intracellular particle trafficking and the performance of bioresponsive bonds for vector capsid modifications.
Human gene therapy 2010;21(9):1155-67.
2010: Gemma Navarro; Gelja Maiwald; Rudolf Haase; Andrey L Rogach; Ernst Wagner; Conchita Tros de Ilarduya; Manfred Ogris
Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery.
Journal of controlled release : official journal of the Controlled Release Society 2010;146(1):99-105.
2010: Ellen Schenk; Magnus Essand; Chris H Bangma; Chris Barber; Jean-Paul Behr; Simon Briggs; Robert Carlisle; Wing-Shing Cheng; Angelika Danielsson; Iris J C Dautzenberg; Helena Dzojic; Patrick Erbacher; Kerry Fisher; April Frazier; Lindsay J Georgopoulos; Rob Hoeben; Stefan Kochanek; Daniela Koppers-Lalic; Robert Kraaij; Florian Kreppel; Leif Lindholm; Maria Magnusson; Norman Maitland; Patrick Neuberg; Berith Nilsson; Manfred Ogris; Jean-Serge Remy; Michelle Scaife; Erik Schooten; Len Seymour; Thomas Totterman; Taco G Uil; Karel Ulbrich; Joke L M Veldhoven-Zweistra; Jeroen de Vrij; Wytske van Weerden; Ernst Wagner; Ralph Willemsen
Clinical adenoviral gene therapy for prostate cancer.
Human gene therapy 2010;21(7):807-13.
2010: Jeroen de Vrij; Ralph A Willemsen; Leif Lindholm; Rob Hoeben; Chris H Bangma; Chris Barber; Jean-Paul Behr; Simon Briggs; Robert Carlisle; Wing-Shing Cheng; Iris J C Dautzenberg; Corrina de Ridder; Helena Dzojic; Patrick Erbacher; Magnus Essand; Kerry Fisher; April Frazier; Lindsay J Georgopoulos; Ian Jennings; Stefan Kochanek; Daniela Koppers-Lalic; Robert Kraaij; Florian Kreppel; Maria Magnusson; Norman Maitland; Patrick Neuberg; Regina Nugent; Manfred Ogris; Jean-Serge Remy; Michelle Scaife; Ellen Schenk-Braat; Erik Schooten; Len Seymour; Michael Slade; Pio Szyjanowicz; Thomas Totterman; Taco G Uil; Karel Ulbrich; Laura van der Weel; Wytske van Weerden; Ernst Wagner; Guy Zuber
Adenovirus-derived vectors for prostate cancer gene therapy.
Human gene therapy 2010;21(7):795-805.
2010: Lilja Thoenes; Miriam Hoehn; Roman Kashirin; Manfred Ogris; Georg J Arnold; Ernst Wagner; Michael Guenther
In vivo chemoresistance of prostate cancer in metronomic cyclophosphamide therapy.
Journal of proteomics 2010;73(7):1342-54.
2010: Ana Cardoso; P Costa; Luis de Almeida; Sérgio Simões; N Plesnila; Carsten Culmsee; Ernst Wagner; M C Pedroso de Lima
Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo.
Journal of controlled release : official journal of the Controlled Release Society 2010;142(3):392-403.
2010: Verena Russ; Thomas Fröhlich; Yunqiu Li; Anna Halama; Manfred Ogris; Ernst Wagner
Improved in vivo gene transfer into tumor tissue by stabilization of pseudodendritic oligoethylenimine-based polyplexes.
The journal of gene medicine 2010;12(2):180-93.
2010: Kevin Buyens; Martin Meyer; Ernst Wagner; Jo Demeester; Stefaan C De Smedt; Niek N Sanders
Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy.
Journal of controlled release : official journal of the Controlled Release Society 2010;141(1):38-41.
2010: Eveline Edith Salcher; Ernst Wagner
Chemically programmed polymers for targeted DNA and siRNA transfection.
Topics in current chemistry 2010;296():227-49.
2010: Kristian Berg; Anette Weyergang; Lina Prasmickaite; Anette Bonsted; Anders Høgset; Marie-Therese R Strand; Ernst Wagner; Pål Kristian Selbo
Photochemical internalization (PCI): a technology for drug delivery.
Methods in molecular biology (Clifton, N.J.) 2010;635():133-45.
2009: Alexander Philipp; Xiaobin Zhao; Peter Tarcha; Ernst Wagner; Arkadi Zintchenko
Hydrophobically modified oligoethylenimines as highly efficient transfection agents for siRNA delivery.
Bioconjugate chemistry 2009;20(11):2055-61.
2009: Arkadi Zintchenko; Andrei S Susha; Massimo Concia; Jochen Feldmann; Ernst Wagner; Andrey L Rogach; Manfred Ogris
Drug nanocarriers labeled with near-infrared-emitting quantum dots (quantoplexes): imaging fast dynamics of distribution in living animals.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(11):1849-56.
2009: Kathrin Klutz; Verena Russ; Michael J Willhauck; Nathalie Wunderlich; Christian Zach; Franz-Josef Gildehaus; Burkhard Göke; Ernst Wagner; Manfred Ogris; Christine Spitzweg
Targeted radioiodine therapy of neuroblastoma tumors following systemic nonviral delivery of the sodium iodide symporter gene.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6079-86.
2009: Haijun Yu; Verena Russ; Ernst Wagner
Influence of the molecular weight of bioreducible oligoethylenimine conjugates on the polyplex transfection properties.
The AAPS journal 2009;11(3):445-55.
2009: Martin Meyer; Christian Dohmen; Alexander Philipp; Daniel Kiener; G Maiwald; Christina Scheu; Manfred Ogris; Ernst Wagner
Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate.
Molecular pharmaceutics 2009;6(3):752-62.
2009: Haijun Yu; Ernst Wagner
Bioresponsive polymers for nonviral gene delivery.
Current opinion in molecular therapeutics 2009;11(2):165-78.
2008: Verena Russ; Michael Günther; Anna Halama; Manfred Ogris; Ernst Wagner
Oligoethylenimine-grafted polypropylenimine dendrimers as degradable and biocompatible synthetic vectors for gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 2008;132(2):131-40.
2008: Ana Cardoso; Sérgio Simões; Luis de Almeida; N Plesnila; Maria C Pedroso De Lima; Ernst Wagner; Carsten Culmsee
Tf-lipoplexes for neuronal siRNA delivery: a promising system to mediate gene silencing in the CNS.
Journal of controlled release : official journal of the Controlled Release Society 2008;132(2):113-23.
2008: Ernst Wagner
Ten-year anniversary of Current Opinion in Molecular Therapeutics: a decade of experience in molecular therapeutics - progress, setbacks and surprises.
Current opinion in molecular therapeutics 2008;10(6):544-7.
2008: Jennifer E Slemmer; Changlian Zhu; Stefan Landshamer; Raimund Trabold; Julia Grohm; Ardavan Ardeshiri; Ernst Wagner; Marva I Sweeney; Klas Blomgren; Carsten Culmsee; John T Weber; Nikolaus Plesnila
Causal role of apoptosis-inducing factor for neuronal cell death following traumatic brain injury.
The American journal of pathology 2008;173(6):1795-805.
2008: Veronika Knorr; Manfred Ogris; Ernst Wagner
An acid sensitive ketal-based polyethylene glycol-oligoethylenimine copolymer mediates improved transfection efficiency at reduced toxicity.
Pharmaceutical research 2008;25(12):2937-45.
2008: Ernst Wagner
The silent (R)evolution of polymeric nucleic acid therapeutics.
Pharmaceutical research 2008;25(12):2920-3.
2008: M Günther; Ernst Wagner; M Ogris
Acrolein: unwanted side product or contribution to antiangiogenic properties of metronomic cyclophosphamide therapy?
Journal of cellular and molecular medicine 2008;12(6B):2704-16.
2008: Alenka Schwerdt; Arkadi Zintchenko; Massimo Concia; Nick Roesen; Kerry Fisher; Lars H Lindner; Rolf Issels; Ernst Wagner; Manfred Ogris
Hyperthermia-induced targeting of thermosensitive gene carriers to tumors.
Human gene therapy 2008;19(11):1283-92.
2008: sergio scirè; S Scirè; Mariano Licciardi; Manfred Ogris; Ernst Wagner; Gaetano Giammona
Polyhydroxyethylaspartamide-spermine copolymers: efficient vectors for gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 2008;131(1):54-63.
2008: Alexander Philipp; Martin Meyer; Ernst Wagner
Extracellular targeting of synthetic therapeutic nucleic acid formulations.
Current gene therapy 2008;8(5):324-34.
2008: Stefan Landshamer; M Hoehn; N Barth; Stéphane Duvezin-Caubet; G Schwake; S Tobaben; I Kazhdan; Barbara Becattini; Stefan Zahler; Nicole Barth; Maurizio Pellecchia; Andreas S Reichert; Nikolaus Plesnila; Ernst Wagner; Carsten Culmsee
Bid-induced release of AIF from mitochondria causes immediate neuronal cell death.
Cell death and differentiation 2008;15(10):1553-63.
2008: Axel Schlossbauer; David Schaffert; Johann Kecht; Ernst Wagner; Thomas Bein
Click chemistry for high-density biofunctionalization of mesoporous silica.
Journal of the American Chemical Society 2008;130(38):12558-9.
2008: K G de Bruin; C Fella; Manfred Ogris; Ernst Wagner; N Ruthardt; Christoph Bräuchle
Dynamics of photoinduced endosomal release of polyplexes.
Journal of controlled release : official journal of the Controlled Release Society 2008;130(2):175-82.
2008: jonathan coulter; H O McCarthy; J Xiang; W Roedl; Ernst Wagner; T Robson; D G Hirst
Nitric oxide--a novel therapeutic for cancer.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2008;19(2):192-8.
2008: Carolin Fella; Greg F Walker; Manfred Ogris; Ernst Wagner
Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;34(4-5):309-20.
2008: Veronika Knorr; Verena Russ; Lars Allmendinger; Manfred Ogris; Ernst Wagner
Acetal linked oligoethylenimines for use as pH-sensitive gene carriers.
Bioconjugate chemistry 2008;19(8):1625-34.
2008: D Schaffert; Ernst Wagner
Gene therapy progress and prospects: synthetic polymer-based systems.
Gene therapy 2008;15(16):1131-8.
2008: Arkadi Zintchenko; Alexander Philipp; Ali Dehshahri; Ernst Wagner
Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity.
Bioconjugate chemistry 2008;19(7):1448-55.
2008: Roosmarijn Vandenbroucke; Bruno G De Geest; Stefan Bonné; Mathieu Vinken; Tamara Van Haecke; Harry Heimberg; Ernst Wagner; Vera Rogiers; Stefaan C De Smedt; Jo Demeester; Niek N Sanders
Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(beta-amino esters).
The journal of gene medicine 2008;10(7):783-94.
2008: Nicole Tietze; Jaroslav Pelisek; Alexander Philipp; Wolfgang Roedl; Thomas Merdan; Peter Tarcha; Manfred Ogris; Ernst Wagner
Induction of apoptosis in murine neuroblastoma by systemic delivery of transferrin-shielded siRNA polyplexes for downregulation of Ran.
Oligonucleotides 2008;18(2):161-74.
2008: Martin Meyer; Alexander Philipp; Reza Oskuee; Claudia Schmidt; Ernst Wagner
Breathing life into polycations: functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery.
Journal of the American Chemical Society 2008;130(11):3272-3.
2008: Jason DeRouchey; Claudia Schmidt; Greg F Walker; Christian Koch; Christian Plank; Ernst Wagner; Joachim O Rädler
Monomolecular assembly of siRNA and poly(ethylene glycol)-peptide copolymers.
Biomacromolecules 2008;9(2):724-32.
2008: Anette Bonsted; Ernst Wagner; Lina Prasmickaite; Anders Høgset; Kristian Berg
Photochemical enhancement of DNA delivery by EGF receptor targeted polyplexes.
Methods in molecular biology (Clifton, N.J.) 2008;434():171-81.
2008: Ernst Wagner
Converging paths of viral and non-viral vector engineering.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(1):1-2.
2008: V Russ; H Elfberg; C Thoma; Julia Kloeckner; Manfred Ogris; Ernst Wagner
Novel degradable oligoethylenimine acrylate ester-based pseudodendrimers for in vitro and in vivo gene transfer.
Gene therapy 2008;15(1):18-29.
2007: Kristian Berg; Marco Folini; Lina Prasmickaite; Pål Kristian Selbo; Anette Bonsted; Birgit Ø Engesaeter; Nadia Zaffaroni; Anette Weyergang; Andreas Dietze; Gunhild M Maelandsmo; Ernst Wagner; Ole-Jacob Norum; Anders Høgset
Photochemical internalization: a new tool for drug delivery.
Current pharmaceutical biotechnology 2007;8(6):362-72.
2007: Manfred Ogris; Arun K Kotha; Nicole Tietze; Ernst Wagner; Fabio Salvatore Palumbo; Gaetano Giammona; Gennara Cavallaro
Novel biocompatible cationic copolymers based on polyaspartylhydrazide being potent as gene vector on tumor cells.
Pharmaceutical research 2007;24(12):2213-22.
2007: Lars Gaedtke; Lilja Thoenes; Carsten Culmsee; Barbara Mayer; Ernst Wagner
Proteomic analysis reveals differences in protein expression in spheroid versus monolayer cultures of low-passage colon carcinoma cells.
Journal of proteome research 2007;6(11):4111-8.
2007: Julia Fahrmeir; Michael Gunther; Nicole Tietze; Ernst Wagner; Manfred Ogris
Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo.
Journal of controlled release : official journal of the Controlled Release Society 2007;122(3):236-45.
2007: Ernst Wagner
Advances in cancer gene therapy: tumor-targeted delivery of therapeutic pDNA, siRNA, and dsRNA nucleic acids.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2007;12 Suppl 1():S77-82.
2007: Martin Meyer; Arkadi Zintchenko; Manfred Ogris; Ernst Wagner
A dimethylmaleic acid-melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential.
The journal of gene medicine 2007;9(9):797-805.
2007: Peter J Tarcha; Jaroslav Pelisek; Thomas Merdan; Jan Waters; Kent Cheung; Katharina von Gersdorff; Carsten Culmsee; Ernst Wagner
Synthesis and characterization of chemically condensed oligoethylenimine containing beta-aminopropionamide linkages for siRNA delivery.
Biomaterials 2007;28(25):3731-40.
2007: Nikolaus Plesnila; L von Baumgarten; Marina Retiounskaia; Doortje Engel; Ardavan Ardeshiri; R Zimmermann; F Hoffmann; Stefan Landshamer; Ernst Wagner; Carsten Culmsee
Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-kappaB transcriptional activity.
Cell death and differentiation 2007;14(8):1529-41.
2007: Veronika Knorr; Lars Allmendinger; Greg F Walker; Franz F Paintner; Ernst Wagner
An acetal-based PEGylation reagent for pH-sensitive shielding of DNA polyplexes.
Bioconjugate chemistry 2007;18(4):1218-25.
2007: Karla de Bruin; Nadia Ruthardt; Katharina von Gersdorff; Ralf Bausinger; Ernst Wagner; Manfred Ogris; Christoph Bräuchle
Cellular dynamics of EGF receptor-targeted synthetic viruses.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(7):1297-305.
2007: Verena Russ; Ernst Wagner
Cell and tissue targeting of nucleic acids for cancer gene therapy.
Pharmaceutical research 2007;24(6):1047-57.
2007: Ernst Wagner
Programmed drug delivery: nanosystems for tumor targeting.
Expert opinion on biological therapy 2007;7(5):587-93.
2007: Ana Cardoso; Sérgio Simões; Luis de Almeida; Jaroslav Pelisek; Carsten Culmsee; Ernst Wagner; Maria C Pedroso De Lima
siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing.
The journal of gene medicine 2007;9(3):170-83.
2007: Kurosh Ameri; Ester M Hammond; C Culmsee; Martin Raida; D M Katschinski; R H Wenger; Ernst Wagner; R J Davis; Tsonwin Hai; Nicholas C Denko; Adrian L Harris
Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway.
Oncogene 2007;26(2):284-9.
2007: Lars Gaedtke; Jaroslav Pelisek; Kai S Lipinski; Christopher J Wrighton; Ernst Wagner
Transcriptionally targeted nonviral gene transfer using a beta-catenin/TCF-dependent promoter in a series of different human low passage colon cancer cells.
Molecular pharmaceutics 2007;4(1):129-39.
2006: Carsten Culmsee; Edith Gasser; Sabine Hansen; Jörg-Christian Tonn; Ernst Wagner; Roland Goldbrunner
Effects of Raf-1 siRNA on human cerebral microvascular endothelial cells: a potential therapeutic strategy for inhibition of tumor angiogenesis.
Brain research 2006;1125(1):147-54.
2006: Julia Kloeckner; Ernst Wagner; Manfred Ogris
Degradable gene carriers based on oligomerized polyamines.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;29(5):414-25.
2006: Julia Kloeckner; Sabine Boeckle; Daniel Persson; Wolfgang Roedl; Manfred Ogris; Kristian Berg; Ernst Wagner
DNA polyplexes based on degradable oligoethylenimine-derivatives: combination with EGF receptor targeting and endosomal release functions.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):115-22.
2006: Martin Meyer; Ernst Wagner
Recent developments in the application of plasmid DNA-based vectors and small interfering RNA therapeutics for cancer.
Human gene therapy 2006;17(11):1062-76.
2006: Katharina von Gersdorff; Niek N Sanders; Roosmarijn Vandenbroucke; Stefaan C De Smedt; Ernst Wagner; Manfred Ogris
The internalization route resulting in successful gene expression depends on both cell line and polyethylenimine polyplex type.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(5):745-53.
2006: Julia Kloeckner; Stefano Bruzzano; Manfred Ogris; Ernst Wagner
Gene carriers based on hexanediol diacrylate linked oligoethylenimine: effect of chemical structure of polymer on biological properties.
Bioconjugate chemistry 2006;17(5):1339-45.
2006: Martin Meyer; Ernst Wagner
pH-responsive shielding of non-viral gene vectors.
Expert opinion on drug delivery 2006;3(5):563-71.
2006: M Günther; D J Waxman; Ernst Wagner; Manfred Ogris
Effects of hypoxia and limited diffusion in tumor cell microenvironment on bystander effect of P450 prodrug therapy.
Cancer gene therapy 2006;13(8):771-9.
2006: Sabine Boeckle; Julia Fahrmeir; Wolfgang Roedl; Manfred Ogris; Ernst Wagner
Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes.
Journal of controlled release : official journal of the Controlled Release Society 2006;112(2):240-8.
2006: Arkadi Zintchenko; Manfred Ogris; Ernst Wagner
Temperature dependent gene expression induced by PNIPAM-based copolymers: potential of hyperthermia in gene transfer.
Bioconjugate chemistry 2006;17(3):766-72.
2006: Lina Prasmickaite; Marit Hellum; Olav Kaalhus; Anders Høgset; Ernst Wagner; Kristian Berg
Photochemical internalization of transgenes controlled by the heat-shock protein 70 promoter.
Photochemistry and photobiology 2006;82(3):809-16.
2006: Jason DeRouchey; Greg F Walker; Ernst Wagner; Joachim O Rädler
Decorated rods: a "bottom-up" self-assembly of monomolecular DNA complexes.
The journal of physical chemistry. B 2006;110(10):4548-54.
2006: Ralf Bausinger; Katharina von Gersdorff; Kevin Braeckmans; Manfred Ogris; Ernst Wagner; Christoph Bräuchle; Andreas Zumbusch
The transport of nanosized gene carriers unraveled by live-cell imaging.
Angewandte Chemie (International ed. in English) 2006;45(10):1568-72.
2006: Jaroslav Pelisek; Lars Gaedtke; Jason DeRouchey; Greg F Walker; Sigrid Nikol; Ernst Wagner
Optimized lipopolyplex formulations for gene transfer to human colon carcinoma cells under in vitro conditions.
The journal of gene medicine 2006;8(2):186-97.
2006: Sabine Boeckle; Ernst Wagner
Optimizing targeted gene delivery: chemical modification of viral vectors and synthesis of artificial virus vector systems.
The AAPS journal 2006;8(4):E731-42.
2006: Alexei Shir; Manfred Ogris; Ernst Wagner; Alexander Levitzki
EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice.
PLoS medicine 2006;3(1):e6.
2005: Carsten Culmsee; Changlian Zhu; Stefan Landshamer; Barbara Becattini; Ernst Wagner; Surya De; Maurizio Pellechia; Klas Blomgren; Nikolaus Plesnila
Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(44):10262-72.
2005: Sabine Boeckle; Ernst Wagner; Manfred Ogris
C- versus N-terminally linked melittin-polyethylenimine conjugates: the site of linkage strongly influences activity of DNA polyplexes.
The journal of gene medicine 2005;7(10):1335-47.
2005: Katharina von Gersdorff; Manfred Ogris; Ernst Wagner
Cryoconserved shielded and EGF receptor targeted DNA polyplexes: cellular mechanisms.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2005;60(2):279-85.
2005: Michael Günther; Ernst Wagner; Manfred Ogris
Specific targets in tumor tissue for the delivery of therapeutic genes.
Current medicinal chemistry. Anti-cancer agents 2005;5(2):157-71.
2005: Greg F Walker; Carolin Fella; Jaroslav Pelisek; Julia Fahrmeir; Sabine Boeckle; Manfred Ogris; Ernst Wagner
Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(3):418-25.
2005: Patrick Couvreur; Diane Barguer; Daan J A Crommelin; Dominique Duchêne; Joachim W Engels; David J Kerr; Povl Krogsgaard-Larsen; Dirk K Meijer; Rodolfo Paoletti; Ernst Wagner
EUFEPS report. Contribution of academic research to discovery and development of medicines: current status and future opportunities.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;24(2-3):245-52.
2005: Ernst Wagner; Carsten Culmsee; Sabine Boeckle
Targeting of polyplexes: toward synthetic virus vector systems.
Advances in genetics 2005;53():333-54.
2005: Klaus Zwiorek; Julia Kloeckner; Ernst Wagner; Conrad Coester
Gelatin nanoparticles as a new and simple gene delivery system.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2005;7(4):22-8.
2005: Marianne Brabec; Daniela Schober; Ernst Wagner; Nora Bayer; Robert Murphy; Dieter Blaas; Renate Fuchs
Opening of size-selective pores in endosomes during human rhinovirus serotype 2 in vivo uncoating monitored by single-organelle flow analysis.
Journal of virology 2005;79(2):1008-16.
2004: Sabine Boeckle; Katharina von Gersdorff; Silke van der Piepen; Carsten Culmsee; Ernst Wagner; Manfred Ogris
Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer.
The journal of gene medicine 2004;6(10):1102-11.
2004: Jaroslav Pelisek; Andreas Kuehnl; Pierre H Rolland; Choukri Mekkaoui; Alexandra Fuchs; Greg F Walker; Manfred Ogris; Ernst Wagner; Sigrid Nikol
Functional analysis of genomic DNA, cDNA, and nucleotide sequence of the mature C-type natriuretic peptide gene in vascular cells.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(9):1646-51.
2004: Julia Kloeckner; Lina Prasmickaite; Anders Høgset; Kristian Berg; Ernst Wagner
Photochemically enhanced gene delivery of EGF receptor-targeted DNA polyplexes.
Journal of drug targeting 2004;12(4):205-13.
2004: Martin C Lenter; Patrick Garidel; Jaroslav Pelisek; Ernst Wagner; Manfred Ogris
Stabilized nonviral formulations for the delivery of MCP-1 gene into cells of the vasculoendothelial system.
Pharmaceutical research 2004;21(4):683-91.
2004: Ernst Wagner; Ralf Kircheis; Greg F Walker
Targeted nucleic acid delivery into tumors: new avenues for cancer therapy.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2004;58(3):152-61.
2004: Christine Magin-Lachmann; George Kotzamanis; Leonardo D'Aiuto; Howard J Cooke; Clare Huxley; Ernst Wagner
In vitro and in vivo delivery of intact BAC DNA -- comparison of different methods.
The journal of gene medicine 2004;6(2):195-209.
2004: Ernst Wagner
Strategies to improve DNA polyplexes for in vivo gene transfer: will "artificial viruses" be the answer?
Pharmaceutical research 2004;21(1):8-14.
2003: Manfred Ogris; Greg Walker; Thomas Blessing; Ralf Kircheis; Markus F Wolschek; Ernst Wagner
Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes.
Journal of controlled release : official journal of the Controlled Release Society 2003;91(1-2):173-81.
2003: Ralf Kircheis; Ernst Wagner
Technology evaluation: TNFerade, GenVec.
Current opinion in molecular therapeutics 2003;5(4):437-47.
2003: B Smrekar; Lionel Wightman; Markus F Wolschek; Cornelia Lichtenberger; R Ruzicka; Manfred Ogris; W Rödl; Malgorzata Kursa; Ernst Wagner; Ralf Kircheis
Tissue-dependent factors affect gene delivery to tumors in vivo.
Gene therapy 2003;10(13):1079-88.
2003: Yaping Li; Manfred Ogris; Ernst Wagner; Jaroslav Pelisek; Martina Rüffer
Nanoparticles bearing polyethyleneglycol-coupled transferrin as gene carriers: preparation and in vitro evaluation.
International journal of pharmaceutics 2003;259(1-2):93-101.
2003: H Gharwan; Lionel Wightman; Ralf Kircheis; Ernst Wagner; K Zatloukal
Nonviral gene transfer into fetal mouse livers (a comparison between the cationic polymer PEI and naked DNA).
Gene therapy 2003;10(9):810-7.
2003: Isabel J Hildebrandt; M Iyer; Ernst Wagner; Sanjiv S Gambhir
Optical imaging of transferrin targeted PEI/DNA complexes in living subjects.
Gene therapy 2003;10(9):758-64.
2003: Christine Magin-Lachmann; George Kotzamanis; Leonardo D'Aiuto; Ernst Wagner; Clare Huxley
Retrofitting BACs with G418 resistance, luciferase, and oriP and EBNA-1 - new vectors for in vitro and in vivo delivery.
BMC biotechnology 2003;3(1):2.
2003: Daniel A Dätwyler; Josef Magyar; Christian Weikert; Lionel Wightman; Ernst Wagner; Hans M Eppenberger
Reactivation of the mitosis-promoting factor in postmitotic cardiomyocytes.
Cells, tissues, organs 2003;175(2):61-71.
2003: Malgorzata Kursa; Greg F Walker; Vanessa Roessler; Manfred Ogris; Wolfgang Roedl; Ralf Kircheis; Ernst Wagner
Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer.
Bioconjugate chemistry 2003;14(1):222-31.
2002: Manfred Ogris; Ernst Wagner
Tumor-targeted gene transfer with DNA polyplexes.
Somatic cell and molecular genetics 2002;27(1-6):85-95.
2002: Sandra S Diebold; Christian Plank; Matt Cotten; Ernst Wagner; Martin Zenke
Mannose receptor-mediated gene delivery into antigen presenting dendritic cells.
Somatic cell and molecular genetics 2002;27(1-6):65-74.
2002: Markus F Wolschek; Christiane Thallinger; Malgorzata Kursa; Vanessa Rössler; Matthew Allen; Cornelia Lichtenberger; Ralf Kircheis; Trevor Lucas; Martin Willheim; Walter Reinisch; Alfred Gangl; Ernst Wagner; Burkhard Jansen
Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice.
Hepatology (Baltimore, Md.) 2002;36(5):1106-14.
2002: Ralf Kircheis; Elinborg Ostermann; Markus F Wolschek; Cornelia Lichtenberger; Christine Magin-Lachmann; Lionel Wightman; Malgorzata Kursa; Ernst Wagner
Tumor-targeted gene delivery of tumor necrosis factor-alpha induces tumor necrosis and tumor regression without systemic toxicity.
Cancer gene therapy 2002;9(8):673-80.
2002: Beatrix Vécsey-Semjén; Karl-Friedrich Becker; Alexandra Sinski; Elizabeth Blennow; Ilja Vietor; Kurt Zatloukal; Hartmut Beug; Ernst Wagner; Lukas A Huber
Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers.
Oncogene 2002;21(30):4646-62.
2002: Ralf Kircheis; Lionel Wightman; Malgorzata Kursa; E Ostermann; Ernst Wagner
Tumor-targeted gene delivery: an attractive strategy to use highly active effector molecules in cancer treatment.
Gene therapy 2002;9(11):731-5.
2002: Markus Düchler; Margret Pengg; Susanne Schüller; Franz Pfneisl; Christoph Bugingo; Gottfried Brem; Ernst Wagner; Karl Schellander; Mathias Müller
Somatic gene transfer into the lactating ovine mammary gland.
The journal of gene medicine 2002;4(3):282-91.
2002: Manfred Ogris; Ernst Wagner
Targeting tumors with non-viral gene delivery systems.
Drug discovery today 2002;7(8):479-85.
2002: Sylvia Brunner; Elke Fürtbauer; Thomas Sauer; Malgorzata Kursa; Ernst Wagner
Overcoming the nuclear barrier: cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(1):80-6.
2001: Ralf Kircheis; Lionel Wightman; Ernst Wagner
Design and gene delivery activity of modified polyethylenimines.
Advanced drug delivery reviews 2001;53(3):341-58.
2001: Thomas Felzmann; M Buchberger; Manfred Lehner; Dieter Printz; Ralf Kircheis; Ernst Wagner; Helmut Gadner; Wolfgang Holter
Functional maturation of dendritic cells by exposure to CD40L transgenic tumor cells, fibroblasts or keratinocytes.
Cancer letters 2001;168(2):145-54.
2001: Lionel Wightman; Ralf Kircheis; Vanessa Rössler; S Carotta; R Ruzicka; Malgorzata Kursa; Ernst Wagner
Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo.
The journal of gene medicine 2001;3(4):362-72.
2001: Thomas Blessing; Malgorzata Kursa; R Holzhauser; Ralf Kircheis; Ernst Wagner
Different strategies for formation of pegylated EGF-conjugated PEI/DNA complexes for targeted gene delivery.
Bioconjugate chemistry 2001;12(4):529-37.
2001: Ralf Kircheis; Thomas Blessing; Sylvia Brunner; Lionel Wightman; Ernst Wagner
Tumor targeting with surface-shielded ligand--polycation DNA complexes.
Journal of controlled release : official journal of the Controlled Release Society 2001;72(1-3):165-70.
2001: Matt Cotten; A Baker; Max L Birnstiel; K Zatloukal; Ernst Wagner
Preparation of adenovirus-polylysine-DNA complexes.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2001;Chapter 12():Unit 12.3.
2001: ML van Slooten; Igal Louria Hayon; Ilan Babai; Zichria Zakay-Rones; Ernst Wagner; Gert Storm; Eli Kedar
Immunoadjuvant activity of interferon-gamma-liposomes co-administered with influenza vaccines.
Biochimica et biophysica acta 2001;1531(1-2):99-110.
2001: Markus Düchler; M Pengg; S Brunner; M Müller; Gottfried Brem; Ernst Wagner
Transfection of epithelial cells is enhanced by combined treatment with mannitol and polyethyleneglycol.
The journal of gene medicine 2001;3(2):115-24.
2001: Manfred Ogris; Peter Steinlein; Sebastian Carotta; Sylvia Brunner; Ernst Wagner
DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression.
AAPS pharmSci 2001;3(3):E21.
2001: Ralf Kircheis; Lionel Wightman; A Schreiber; B Robitza; Vanessa Rössler; Malgorzata Kursa; Ernst Wagner
Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application.
Gene therapy 2001;8(1):28-40.
2000: Thomas Felzmann; M Buchberger; M Jechlinger; Ralf Kircheis; Ernst Wagner; Helmut Gadner
Xenogenization by tetanus toxoid loading into lymphoblastoid cell lines and primary human tumor cells mediated by polycations and liposomes.
Cancer letters 2000;161(2):241-50.
2000: Ralf Kircheis; Zaruhi Küpcü; G Wallner; Vanessa Rössler; Tamás Schweighoffer; Ernst Wagner
Interleukin-2 gene-modified allogeneic melanoma cell vaccines can induce cross-protection against syngeneic tumors in mice.
Cancer gene therapy 2000;7(6):870-8.
2000: Manfred Ogris; Ernst Wagner; Peter Steinlein
A versatile assay to study cellular uptake of gene transfer complexes by flow cytometry.
Biochimica et biophysica acta 2000;1474(2):237-43.
2000: M Huber; A Limat; Ernst Wagner; D Hohl
Efficient in vitro transfection of human keratinocytes with an adenovirus-enhanced receptor-mediated system.
The Journal of investigative dermatology 2000;114(4):661-6.
2000: Sylvia Brunner; T Sauer; Sebastian Carotta; Matt Cotten; M Saltik; Ernst Wagner
Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus.
Gene therapy 2000;7(5):401-7.
2000: Ernst Wagner; K Culver
Molecular therapeutics at the entrance into the 21st century.
Current opinion in molecular therapeutics 2000;2(1):i-ii.
2000: ML van Slooten; Gert Storm; A Zoephel; Zaruhi Küpcü; Otto Boerman; Daan J A Crommelin; Ernst Wagner; Ralf Kircheis
Liposomes containing interferon-gamma as adjuvant in tumor cell vaccines.
Pharmaceutical research 2000;17(1):42-8.
1999: Lionel Wightman; E Patzelt; Ernst Wagner; Ralf Kircheis
Development of transferrin-polycation/DNA based vectors for gene delivery to melanoma cells.
Journal of drug targeting 1999;7(4):293-303.
1999: Sandra S Diebold; M Kursa; Ernst Wagner; Matt Cotten; Martin Zenke
Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells.
The Journal of biological chemistry 1999;274(27):19087-94.
1999: Wolfgang Zauner; Sylvia Brunner; Michael Buschle; Manfred Ogris; Ernst Wagner
Differential behaviour of lipid based and polycation based gene transfer systems in transfecting primary human fibroblasts: a potential role of polylysine in nuclear transport.
Biochimica et biophysica acta 1999;1428(1):57-67.
1999: ML van Slooten; Ralf Kircheis; FJ Koppenhagen; Ernst Wagner; Gert Storm
Liposomes as cytokine-supplement in tumor cell-based vaccines.
International journal of pharmaceutics 1999;183(1):33-6.
1999: S Schreiber; E Kämpgen; Ernst Wagner; D Pirkhammer; J Trcka; H Korschan; A Lindemann; Roland Dorffner; Harald Kittler; F Kasteliz; Z Küpcü; A Sinski; Kurt Zatloukal; Michael Buschle; Walter Schmidt; Max L Birnstiel; RE Kempe; T Voigt; H A Weber; Hubert Pehamberger; Roland Mertelsmann; Eva-B Bröcker; Klaus Wolff; Georg Stingl
Immunotherapy of metastatic malignant melanoma by a vaccine consisting of autologous interleukin 2-transfected cancer cells: outcome of a phase I study.
Human gene therapy 1999;10(6):983-93.
1999: Manfred Ogris; Sylvia Brunner; S Schüller; Ralf Kircheis; Ernst Wagner
PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery.
Gene therapy 1999;6(4):595-605.
1999: Sandra S Diebold; H Lehrmann; M Kursa; Ernst Wagner; Matt Cotten; Martin Zenke
Efficient gene delivery into human dendritic cells by adenovirus polyethylenimine and mannose polyethylenimine transfection.
Human gene therapy 1999;10(5):775-86.
1999: Ralf Kircheis; S Schüller; Sylvia Brunner; Manfred Ogris; K H Heider; Wolfgang Zauner; Ernst Wagner
Polycation-based DNA complexes for tumor-targeted gene delivery in vivo.
The journal of gene medicine 1999;1(2):111-20.
1998: Manfred Ogris; Peter Steinlein; Malgorzata Kursa; Karl Mechtler; Ralf Kircheis; Ernst Wagner
The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells.
Gene therapy 1998;5(10):1425-33.
1998: FJ Koppenhagen; Zaruhi Küpcü; G Wallner; Daan J A Crommelin; Ernst Wagner; Gert Storm; Ralf Kircheis
Sustained cytokine delivery for anticancer vaccination: liposomes as alternative for gene-transfected tumor cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(8):1881-6.
1998: A Kichler; Wolfgang Zauner; Manfred Ogris; Ernst Wagner
Influence of the DNA complexation medium on the transfection efficiency of lipospermine/DNA particles.
Gene therapy 1998;5(6):855-60.
1998: Ralf Kircheis; Zaruhi Küpcü; G Wallner; Ernst Wagner
Cytokine gene-modified tumor cells for prophylactic and therapeutic vaccination: IL-2, IFN-gamma, or combination IL-2 + IFN-gamma.
Cytokines, cellular & molecular therapy 1998;4(2):95-103.
1998: Richard P Harbottle; RG Cooper; Stephen Hart; A Ladhoff; Tristan McKay; A M Knight; Ernst Wagner; Andrew D Miller; Charles Coutelle
An RGD-oligolysine peptide: a prototype construct for integrin-mediated gene delivery.
Human gene therapy 1998;9(7):1037-47.
1998: Ernst Wagner
Effects of membrane-active agents in gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 1998;53(1-3):155-8.
1998: Sandra S Diebold; Matt Cotten; Ernst Wagner; Martin Zenke
Gene-modified dendritic cells by receptor-mediated transfection.
Advances in experimental medicine and biology 1998;451():449-55.
1998: S Finke; B Trojaneck; P Lefterova; M Csipai; Ernst Wagner; R Kircheis; Andreas Neubauer; Dieter Huhn; Burghardt Wittig; Ingo G H Schmidt-Wolf
Increase of proliferation rate and enhancement of antitumor cytotoxicity of expanded human CD3+ CD56+ immunologic effector cells by receptor-mediated transfection with the interleukin-7 gene.
Gene therapy 1998;5(1):31-9.
1997: Ralf Kircheis; A Kichler; G Wallner; Malgorzata Kursa; Manfred Ogris; Thomas Felzmann; M Buchberger; Ernst Wagner
Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery.
Gene therapy 1997;4(5):409-18.
1997: Wolfgang Zauner; A Kichler; Walter Schmidt; Karl Mechtler; Ernst Wagner
Glycerol and polylysine synergize in their ability to rupture vesicular membranes: a mechanism for increased transferrin-polylysine-mediated gene transfer.
Experimental cell research 1997;232(1):137-45.
1997: O Ebert; S Finke; A Salahi; M Herrmann; B Trojaneck; P Lefterova; Ernst Wagner; R Kircheis; Dieter Huhn; Folke Schriever; Ingo G H Schmidt-Wolf
Lymphocyte apoptosis: induction by gene transfer techniques.
Gene therapy 1997;4(4):296-302.
1997: Georg Stingl; Eva-B Bröcker; Roland Mertelsmann; Klaus Wolff; S Schreiber; E Kämpgen; Achim Schneeberger; J Trcka; U Brennscheidt; Hendrik Veelken; Max L Birnstiel; Kurt Zatloukal; G Maass; Ernst Wagner; Michael Buschle; E R Kempe; H A Weber; T Voigt
Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene.
Journal of molecular medicine (Berlin, Germany) 1997;75(4):297-9.
1997: P L Felgner; Y Barenholz; J P Behr; Seng Cheng; P Cullis; L Huang; J A Jessee; L Seymour; F Szoka; Alain THIERRY; Ernst Wagner; G Wu
Nomenclature for synthetic gene delivery systems.
Human gene therapy 1997;8(5):511-2.
1997: A Kichler; Karl Mechtler; J P Behr; Ernst Wagner
Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer.
Bioconjugate chemistry 1997;8(2):213-21.
1997: Jean-Luc Coll; Ernst Wagner; Valérie Combaret; K Metchler; H Amstutz; I Iacono-Di-Cacito; N Simon; Marie-Christine Favrot
In vitro targeting and specific transfection of human neuroblastoma cells by chCE7 antibody-mediated gene transfer.
Gene therapy 1997;4(2):156-61.
1996: Laurent Gagnoux-Palacios; J Vailly; M Durand-Clement; Ernst Wagner; Jean-Paul Ortonne; Guerrino Meneguzzi
Functional Re-expression of laminin-5 in laminin-gamma2-deficient human keratinocytes modifies cell morphology, motility, and adhesion.
The Journal of biological chemistry 1996;271(31):18437-44.
1996: C Plank; Karl Mechtler; Francis C Szoka; Ernst Wagner
Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery.
Human gene therapy 1996;7(12):1437-46.
1996: C Morrison; Ernst Wagner
Extrachromosomal recombination occurs efficiently in cells defective in various DNA repair systems.
Nucleic acids research 1996;24(11):2053-8.
1996: Wolfgang Zauner; A Kichler; Walter Schmidt; A Sinski; Ernst Wagner
Glycerol enhancement of ligand-polylysine/DNA transfection.
BioTechniques 1996;20(5):905-13.
1996: Georg Stingl; E B Brŏcker; Roland Mertelsmann; Klaus Wolff; S Schreiber; E Kămpgen; Achim Schneeberger; W Dummer; U Brennscheid; Hendrik Veelken; Max L Birnstiel; Kurt Zatloukal; Walter Schmidt; G Maass; Ernst Wagner; M Baschle; M Giese; E R Kempe; H A Weber; T Voigt
Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene.
Human gene therapy 1996;7(4):551-63.
1996: László Bögre; Claudia Jonak; M Mink; Irute Meskiene; Jan Traas; D T Ha; I Swoboda; C Plank; Ernst Wagner; Erwin Heberle-Bors; Heribert Hirt
Developmental and cell cycle regulation of alfalfa nucMs1, a plant homolog of the yeast Nsr1 and mammalian nucleolin.
The Plant cell 1996;8(3):417-28.
1995: E Prchla; C Plank; Ernst Wagner; Dieter Blaas; Renate Fuchs
Virus-mediated release of endosomal content in vitro: different behavior of adenovirus and rhinovirus serotype 2.
The Journal of cell biology 1995;131(1):111-23.
1995: Michael Buschle; Matt Cotten; H Kirlappos; Karl Mechtler; G Schaffner; Wolfgang Zauner; Max L Birnstiel; Ernst Wagner
Receptor-mediated gene transfer into human T lymphocytes via binding of DNA/CD3 antibody particles to the CD3 T cell receptor complex.
Human gene therapy 1995;6(6):753-61.
1995: Kurt Zatloukal; Achim Schneeberger; M Berger; Walter Schmidt; F Koszik; R Kutil; Matt Cotten; Ernst Wagner; Michael Buschle; G Maass
Elicitation of a systemic and protective anti-melanoma immune response by an IL-2-based vaccine. Assessment of critical cellular and molecular parameters.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(7):3406-19.
1995: T von Rüden; L Stingl; Matt Cotten; Ernst Wagner; Kurt Zatloukal
Generation of high-titer retroviral vectors following receptor-mediated, adenovirus-augmented transfection.
BioTechniques 1995;18(3):484-9.
1995: T Moll; M Czyz; H Holzmüller; Renate Hofer-Warbinek; Ernst Wagner; H Winkler; Fritz H Bach; Erhard Hofer
Regulation of the tissue factor promoter in endothelial cells. Binding of NF kappa B-, AP-1-, and Sp1-like transcription factors.
The Journal of biological chemistry 1995;270(8):3849-57.
1995: Wolfgang Zauner; Dieter Blaas; Ernst Kuechler; Ernst Wagner
Rhinovirus-mediated endosomal release of transfection complexes.
Journal of virology 1995;69(2):1085-92.
1994: Matt Cotten; M Saltik; M Kursa; Ernst Wagner; G Maass; M L Birnstiel
Psoralen treatment of adenovirus particles eliminates virus replication and transcription while maintaining the endosomolytic activity of the virus capsid.
Virology 1994;205(1):254-61.
1994: Sasa Frank; K Krasznai; S Durovic; Eva M Lobentanz; Hans Dieplinger; Ernst Wagner; K Zatloukal; M Cotten; Gerd Utermann; Gerhard Kostner
High-level expression of various apolipoprotein(a) isoforms by "transferrinfection": the role of kringle IV sequences in the extracellular association with low-density lipoprotein.
Biochemistry 1994;33(40):12329-39.
1994: O Zelphati; Ernst Wagner; Lee Leserman
Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes.
Antiviral research 1994;25(1):13-25.
1994: M Thurnher; Ernst Wagner; H Clausen; Karl Mechtler; S Rusconi; André Dinter; Max L Birnstiel; Eric G Berger; M Cotten
Carbohydrate receptor-mediated gene transfer to human T leukaemic cells.
Glycobiology 1994;4(4):429-35.
1994: R K Batra; F Wang-Johanning; Ernst Wagner; R I Garver; D T Curiel
Receptor-mediated gene delivery employing lectin-binding specificity.
Gene therapy 1994;1(4):255-60.
1994: Matt Cotten; A Baker; M Saltik; Ernst Wagner; Michael Buschle
Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary human cells in the presence of adenovirus.
Gene therapy 1994;1(4):239-46.
1994: K Zatloukal; M Cotten; M Berger; W Schmidt; Ernst Wagner; M L Birnstiel
In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):5148-52.
1994: Q Cheng; C A Cant; T Moll; Renate Hofer-Warbinek; Ernst Wagner; M L Birnstiel; Fritz H Bach; Rainer de Martin
NK-kappa B subunit-specific regulation of the I kappa B alpha promoter.
The Journal of biological chemistry 1994;269(18):13551-7.
1994: C Plank; B Oberhauser; Karl Mechtler; C Koch; Ernst Wagner
The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems.
The Journal of biological chemistry 1994;269(17):12918-24.
1994: Tyler J Curiel; D R Cook; C Bogedain; Wolfgang Jilg; Gail S Harrison; M Cotten; David T Curiel; Ernst Wagner
Efficient foreign gene expression in Epstein-Barr virus-transformed human B-cells.
Virology 1994;198(2):577-85.
1994: D R Cook; Ian H Maxwell; L Michael Glode; Françoise Maxwell; J O Stevens; M B Purner; Ernst Wagner; David T Curiel; Tyler J Curiel
Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate.
Cancer biotherapy 1994;9(2):131-41.
1994: Kurt Zatloukal; Achim Schneeberger; M Berger; F Koszik; Walter Schmidt; Ernst Wagner; Matt Cotten; Michael Buschle; G Maass; Georg Stingl
Genetic modification of cells by receptor-mediated adenovirus-augmented gene delivery: a new approach for immunotherapy of cancer.
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():171-6.
1993: K Zatloukal; W Schmidt; M Cotten; Ernst Wagner; G Stingl; M L Birnstiel
Somatic gene therapy for cancer: the utility of transferrinfection in generating 'tumor vaccines'.
Gene 1993;135(1-2):199-207.
1993: M Cotten; Ernst Wagner
Non-viral approaches to gene therapy.
Current opinion in biotechnology 1993;4(6):705-10.
1993: C E Harris; S Agarwal; P Hu; Ernst Wagner; D T Curiel
Receptor-mediated gene transfer to airway epithelial cells in primary culture.
American journal of respiratory cell and molecular biology 1993;9(4):441-7.
1993: M Cotten; Ernst Wagner; K Zatloukal; Max L Birnstiel
Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants.
Journal of virology 1993;67(7):3777-85.
1993: S I Michael; C H Huang; M U Rømer; Ernst Wagner; P C Hu; D T Curiel
Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway.
The Journal of biological chemistry 1993;268(10):6866-9.
1993: L Gao; Ernst Wagner; M Cotten; S Agarwal; C Harris; M Rømer; L Miller; P C Hu; D Curiel
Direct in vivo gene transfer to airway epithelium employing adenovirus-polylysine-DNA complexes.
Human gene therapy 1993;4(1):17-24.
1993: Matt Cotten; Ernst Wagner; Max L Birnstiel
Receptor-mediated transport of DNA into eukaryotic cells.
Methods in enzymology 1993;217():618-44.
1992: C Plank; Kurt Zatloukal; Matt Cotten; Karl Mechtler; Ernst Wagner
Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand.
Bioconjugate chemistry 1992;3(6):533-9.
1992: Kurt Zatloukal; Ernst Wagner; Matt Cotten; S Phillips; C Plank; Peter Steinlein; D T Curiel; Max L Birnstiel
Transferrinfection: a highly efficient way to express gene constructs in eukaryotic cells.
Annals of the New York Academy of Sciences 1992;660():136-53.
1992: Ernst Wagner; C Plank; Kurt Zatloukal; Matt Cotten; Max L Birnstiel
Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):7934-8.
1992: Ernst Wagner; Kurt Zatloukal; Matt Cotten; H Kirlappos; Karl Mechtler; D T Curiel; Max L Birnstiel
Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(13):6099-103.
1992: M Cotten; Ernst Wagner; K Zatloukal; S Phillips; D T Curiel; Max L Birnstiel
High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(13):6094-8.
1992: D T Curiel; Ernst Wagner; M Cotten; M L Birnstiel; S Agarwal; C M Li; S Loechel; P C Hu
High-efficiency gene transfer mediated by adenovirus coupled to DNA-polylysine complexes.
Human gene therapy 1992;3(2):147-54.
1992: D T Curiel; S Agarwal; M U Rømer; Ernst Wagner; M Cotten; M L Birnstiel; Richard C Boucher
Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway.
American journal of respiratory cell and molecular biology 1992;6(3):247-52.
1992: B Oberhauser; Ernst Wagner
Effective incorporation of 2'-O-methyl-oligoribonucleotides into liposomes and enhanced cell association through modification with thiocholesterol.
Nucleic acids research 1992;20(3):533-8.
1991: Ernst Wagner; B Oberhauser; A Holzner; H Brunar; G Issakides; G Schaffner; Matt Cotten; M Knollmüller; C R Noe
A simple procedure for the preparation of protected 2'-O-methyl or 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites.
Nucleic acids research 1991;19(21):5965-71.
1991: D T Curiel; S Agarwal; Ernst Wagner; M Cotten
Adenovirus enhancement of transferrin-polylysine-mediated gene delivery.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8850-4.
1991: Ernst Wagner; Matt Cotten; Karl Mechtler; H Kirlappos; Max L Birnstiel
DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety.
Bioconjugate chemistry 1991;2(4):226-31.
1991: Matt Cotten; B Oberhauser; H Brunar; A Holzner; G Issakides; C R Noe; G Schaffner; Ernst Wagner; Max L Birnstiel
2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event.
Nucleic acids research 1991;19(10):2629-35.
1991: Ernst Wagner; Matt Cotten; R Foisner; Max L Birnstiel
Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(10):4255-9.
1990: Matt Cotten; F Längle-Rouault; H Kirlappos; Ernst Wagner; Karl Mechtler; Martin Zenke; H Beug; Max L Birnstiel
Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(11):4033-7.
1990: Martin Zenke; Peter Steinlein; Ernst Wagner; Matt Cotten; H Beug; Max L Birnstiel
Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3655-9.
1990: Ernst Wagner; Martin Zenke; Matt Cotten; H Beug; Max L Birnstiel
Transferrin-polycation conjugates as carriers for DNA uptake into cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(9):3410-4.