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Stephen Obaro

Research Profile

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Publications

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Chinyere K Okoro; Julian Parkhill; Christopher M Parry; Milagritos D Tapia; Sharon Tennant; John Wain; Manar N Al-Mashhadani; Pedro L Alonso; Thomas R Connor; Elizabeth de Pinna; Melita A Gordon; Simon R Harris; Robert S Heyderman; Samuel Kariuki; Robert A Kingsley; Myron M Levine; Calman A MacLennan; Inacio Mandomando; Chisomo L Msefula; Stephen Obaro; Gordon Dougan
Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa.
Stephen Obaro
Does sickle cell disease protect against HIV/AIDS?
Ramadhan Hashim; Raymond Hutubessy; Maria Teresa Aguado; Mohammad Ali; Said M Ali; Na Yoon Chang; John D Clemens; Jacqueline L Deen; Godwin Enwere; Ahmed M Khatib; Marie Paule Kieny; Deok Ryun Kim; Benedikt Ley; Anna Lena Lopez; Stephen Obaro; Jin Kyung Park; Rita Reyburn; David A Sack; Abdul A Saleh; Christian Schaetti; Attiye J Shaame; Sunheang Shin; Kamala Thriemer; Lorenz Von Seidlein; Mohamed S Jiddawi
Safety of the recombinant cholera toxin B subunit, killed whole-cell (rBS-WC) oral cholera vaccine in pregnancy.

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All Publications

2012: Chinyere K Okoro; Julian Parkhill; Christopher M Parry; Milagritos D Tapia; Sharon Tennant; John Wain; Manar N Al-Mashhadani; Pedro L Alonso; Thomas R Connor; Elizabeth de Pinna; Melita A Gordon; Simon R Harris; Robert S Heyderman; Samuel Kariuki; Robert A Kingsley; Myron M Levine; Calman A MacLennan; Inacio Mandomando; Chisomo L Msefula; Stephen Obaro; Gordon Dougan
Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa.
Nature genetics 2012;44(11):1215-21.
2012: Stephen Obaro
Does sickle cell disease protect against HIV/AIDS?
Sexually transmitted infections 2012;88(7):533.
2012: Ramadhan Hashim; Raymond Hutubessy; Maria Teresa Aguado; Mohammad Ali; Said M Ali; Na Yoon Chang; John D Clemens; Jacqueline L Deen; Godwin Enwere; Ahmed M Khatib; Marie Paule Kieny; Deok Ryun Kim; Benedikt Ley; Anna Lena Lopez; Stephen Obaro; Jin Kyung Park; Rita Reyburn; David A Sack; Abdul A Saleh; Christian Schaetti; Attiye J Shaame; Sunheang Shin; Kamala Thriemer; Lorenz Von Seidlein; Mohamed S Jiddawi
Safety of the recombinant cholera toxin B subunit, killed whole-cell (rBS-WC) oral cholera vaccine in pregnancy.
PLoS neglected tropical diseases 2012;6(7):e1743.
2011: Stephen Obaro
5 versus 10 days of ceftriaxone for bacterial meningitis in children.
Lancet 2011;378(9803):1624-5; author reply 1625-6.
2011: Stephen Obaro; Brian Greenwood
Malaria and bacteraemia in African children.
Lancet 2011;378(9799):1281-2.
2011: Jessica Vanhomwegen; Awewura Kwara; Melissa Martin; Fizza S Gillani; Arnaud Fontanet; Peninnah Mutungi; Joyce Crellin; Stephen Obaro; Michael Gosciminski; E Jane Carter; Nalin Rastogi
Impact of immigration on the molecular epidemiology of tuberculosis in Rhode Island.
Journal of clinical microbiology 2011;49(3):834-44.
2011: Sok Kean Khoo; Mrutyunjaya Parida; David Petillo; James Resau; Aik Choon Tan; Stephen Obaro
Host response transcriptional profiling reveals extracellular components and ABC (ATP-binding cassette) transporters gene enrichment in typhoid fever-infected Nigerian children.
BMC infectious diseases 2011;11():241.
2011: Stephen Obaro; Comfort Ochigbo; Damola Ogundeji; Grace Olanipekun; Michael Olugbile; Adekunle Otuneye; Denis Shetima; Patience Ahmed; Theresa Ajose; Kevin Brooks; Uduak Essen; Khalid Ibrahim; David Idiong; Walid Khalife; Lovett Lawson; Richard Adegbola
Community acquired bacteremia in young children from central Nigeria--a pilot study.
BMC infectious diseases 2011;11():137.
2010: Stephen Obaro
Rotavirus vaccine efficacy in African and Asian countries.
Lancet 2010;376(9756):1897; author reply 1898.
2010: Enrico M Novelli; James B Hittner; Gregory C Davenport; Collins Ouma; Tom Were; Stephen Obaro; Sandra Kaplan; John M Ong'echa; Douglas J Perkins
Clinical predictors of severe malarial anaemia in a holoendemic Plasmodium falciparum transmission area.
British journal of haematology 2010;149(5):711-21.
2010: Nishaki Mehta; Coleen K Cunningham; Patricia Flynn; Joyce Pepe; Stephen Obaro; Bill G Kapogiannis; James Bethel; Katherine Luzuriaga
Impaired generation of hepatitis B virus-specific memory B cells in HIV infected individuals following vaccination.
Vaccine 2010;28(21):3672-8.
2010: Stephen Obaro
Preventable deaths in sickle-cell anaemia in African children.
Lancet 2010;375(9713):460; author reply 461.
2009: Stephen Obaro
Pneumococcal infections and sickle cell disease in Africa: does absence of evidence imply evidence of absence?
Archives of disease in childhood 2009;94(9):713-6.
2009: Stephen Obaro
Seven-valent pneumococcal conjugate vaccines for developing countries.
Expert review of vaccines 2009;8(8):1051-61.
2007: Stephen Obaro
Prediction rule for bacterial meningitis in children.
JAMA : the journal of the American Medical Association 2007;297(15):1653-4; author reply 1654-5.
2006: Stephen Obaro; Martin O Ota
Sense and the science of childhood immunization: can we achieve more with less?
Vaccine 2006;24(42-43):6460-7.
2006: Joseph I Harwell; Stephen Obaro
Antiretroviral therapy for children: substantial benefit but limited access.
JAMA : the journal of the American Medical Association 2006;296(3):330-1.
2006: Stephen Obaro; Shabir A Madhi
Bacterial pneumonia vaccines and childhood pneumonia: are we winning, refining, or redefining?
The Lancet infectious diseases 2006;6(3):150-61.
2005: Richard A Adegbola; Ousman Secka; George Lahai; Nellie Lloyd-Evans; Alpha Njie; Stanley Usen; Claire Oluwalana; Stephen Obaro; Martin Weber; Tumani Corrah; Kim Mulholland; Keith P W J McAdam; Brian Greenwood; Paul Milligan
Elimination of Haemophilus influenzae type b (Hib) disease from The Gambia after the introduction of routine immunisation with a Hib conjugate vaccine: a prospective study.
Lancet 2005;366(9480):144-50.
2005: Thomas Cherian; E Kim Mulholland; John B Carlin; Harald Ostensen; RUHUL AMIN; Margaret de Campo; David Greenberg; Rosanna Lagos; Marilla G Lucero; Shabir A Madhi; Katherine L O'Brien; Stephen Obaro; mark steinhoff
Standardized interpretation of paediatric chest radiographs for the diagnosis of pneumonia in epidemiological studies.
Bulletin of the World Health Organization 2005;83(5):353-9.
2005: Felicity T Cutts; Syed M A Zaman; Godwin Enwere; Shabbar Jaffar; Orin S Levine; J B Okoko; Claire Oluwalana; Adeola Vaughan; Stephen Obaro; Amanda Leach; Keith P W J McAdam; Ekow Biney; M Saaka; U Onwuchekwa; F Yallop; NATHANIEL PIERCE; Brian M Greenwood; Richard A Adegbola
Efficacy of nine-valent pneumococcal conjugate vaccine against pneumonia and invasive pneumococcal disease in The Gambia: randomised, double-blind, placebo-controlled trial.
Lancet 2005;365(9465):1139-46.
2005: Stephen Obaro; Phyllis Losikoff; Joseph I Harwell; David Pugatch
Failure of serial human immunodeficiency virus type 1 DNA polymerase chain reactions to identify human immunodeficiency virus type 1 clade A/G.
The Pediatric infectious disease journal 2005;24(2):183-4.
2004: Hedwig E Deubzer; Stephen Obaro; Vanessa O Newman; Richard A Adegbola; Brian M Greenwood; Don C Henderson
Colostrum obtained from women vaccinated with pneumococcal vaccine during pregnancy inhibits epithelial adhesion of Streptococcus pneumoniae.
The Journal of infectious diseases 2004;190(10):1758-61.
2004: Stephen Obaro; Hedwig E Deubzer; Vanessa O Newman; Richard A Adegbola; Brian M Greenwood; Don C Henderson
Serotype-specific pneumococcal antibodies in breast milk of Gambian women immunized with a pneumococcal polysaccharide vaccine during pregnancy.
The Pediatric infectious disease journal 2004;23(11):1023-9.
2004: Stephen Obaro; David Pugatch; Katherine Luzuriaga
Immunogenicity and efficacy of childhood vaccines in HIV-1-infected children.
The Lancet infectious diseases 2004;4(8):510-8.
2003: Angela Allen; Stephen Obaro; Kalifa Bojang; Agnes A Awomoyi; Brian M Greenwood; Hilton Whittle; Giorgio Sirugo; Melanie J Newport
Variation in Toll-like receptor 4 and susceptibility to group A meningococcal meningitis in Gambian children.
The Pediatric infectious disease journal 2003;22(11):1018-9.
2003: Stephen Obaro; A Palmer
Vaccines for children: policies, politics and poverty.
Vaccine 2003;21(13-14):1423-31.
2003: Michael Poshkus; Stephen Obaro
Dexamethasone in adults with bacterial meningitis.
The New England journal of medicine 2003;348(10):954-7; author reply 954-7.
2002: Stephen Obaro
Dexamethasone in acute bacterial meningitis.
Lancet 2002;360(9345):1609-10; author reply 1610-1.
2002: Stephen Obaro; Godwin Enwere; MARIA KNOLL; Shabbar Jaffar; David Goldblatt; Kate Brainsby; Hans O Hallander; Pamela McInnes; Brian M Greenwood; Keith P W J McAdam
Safety and immunogenicity of pneumococcal conjugate vaccine in combination with diphtheria, tetanus toxoid, pertussis and Haemophilus influenzae type b conjugate vaccine.
The Pediatric infectious disease journal 2002;21(10):940-7.
2002: Stephen Obaro
The new pneumococcal vaccine.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2002;8(10):623-33.
2002: Stephen Obaro; Richard A Adegbola
The pneumococcus: carriage, disease and conjugate vaccines.
Journal of medical microbiology 2002;51(2):98-104.
2001: G Enwere; Stephen Obaro
Diagnosis of bacterial meningitis.
Lancet 2001;358(9292):1549-50.
2001: Stephen Obaro
Protein conjugate vaccines--how much is enough?
Trends in microbiology 2001;9(8):364-5.
2001: Richard A Adegbola; Stephen Obaro; Ekow Biney; Brian M Greenwood
Evaluation of Binax now Streptococcus pneumoniae urinary antigen test in children in a community with a high carriage rate of pneumococcus.
The Pediatric infectious disease journal 2001;20(7):718-9.
2001: Stephen Obaro
Differences in invasive pneumococcal serotypes.
Lancet 2001;357(9270):1800-1.
2001: Jenny Maclennan; Stephen Obaro; J Deeks; D Lake; C Elie; G Carlone; E Richard Moxon; B Greenwood
Immunologic memory 5 years after meningococcal A/C conjugate vaccination in infancy.
The Journal of infectious diseases 2001;183(1):97-104.
2000: Stephen Obaro
Confronting the pneumococcus: a target shift or bullet change?
Vaccine 2000;19(9-10):1211-7.
2000: Stephen Obaro
Respiratory diseases in Africa: causes and effects.
Lancet 2000;356 Suppl():s55.
2000: Anu Nurkka; Jenny Maclennan; Virva Jäntti; Stephen Obaro; B Greenwood; Helena Käyhty
Salivary antibody response to vaccination with meningococcal A/C polysaccharide vaccine in previously vaccinated and unvaccinated Gambian children.
Vaccine 2000;19(4-5):547-56.
2000: Stephen Obaro; Richard A Adegbola; JA Tharpe; Edwin W Ades; K P McAdam; George M Carlone; Jacquelyn S Sampson
Pneumococcal surface adhesin A antibody concentration in serum and nasopharyngeal carriage of Streptococcus pneumoniae in young African infants.
Vaccine 2000;19(4-5):411-2.
2000: Jenny Maclennan; Rachel Urwin; Stephen Obaro; D Griffiths; B Greenwood; Martin C J Maiden
Carriage of serogroup W-135, ET-37 meningococci in The Gambia: implications for immunisation policy?
Lancet 2000;356(9235):1078.
2000: Godwin Enwere; Martin O C Ota; Stephen Obaro
Electrolyte derangement in cerebral malaria: a case for a more aggressive approach to the management of hyponatraemia.
Annals of tropical medicine and parasitology 2000;94(6):541-7.
2000: Stephen Obaro
Pneumocystis carinii pneumonia in Malawian children.
Lancet 2000;355(9220):2074-5.
2000: Stephen Obaro; Richard A Adegbola; I Chang; Winston A S Banya; Shabbar Jaffar; K W Mcadam; Brian M Greenwood
Safety and immunogenicity of a nonavalent pneumococcal vaccine conjugated to CRM197 administered simultaneously but in a separate syringe with diphtheria, tetanus and pertussis vaccines in Gambian infants.
The Pediatric infectious disease journal 2000;19(5):463-9.
2000: Richard A Adegbola; Stephen Obaro
Diagnosis of childhood pneumonia in the tropics.
Annals of tropical medicine and parasitology 2000;94(3):197-207.
2000: Kalifa Bojang; Stephen Obaro; Linda Morison; Brian M Greenwood
A prospective evaluation of a clinical algorithm for the diagnosis of malaria in Gambian children.
Tropical medicine & international health : TM & IH 2000;5(4):231-6.
2000: Stephen Obaro
Control of meningococcal disease in west Africa.
Lancet 2000;355(9210):1184-5.
2000: Stephen Obaro
Prospects for pneumococcal vaccination in African children.
Acta tropica 2000;75(2):141-53.
1999: Shabbar Jaffar; Amanda Leach; Andrew J Hall; Stephen Obaro; Keith P W J McAdam; Peter G Smith; Brian M Greenwood
Preparation for a pneumococcal vaccine trial in The Gambia: individual or community randomisation?
Vaccine 1999;18(7-8):633-40.
1999: Godwin Enwere; Martin O C Ota; Stephen Obaro
The host response in malaria and depression of defence against tuberculosis.
Annals of tropical medicine and parasitology 1999;93(7):669-78.
1999: Jenny Maclennan; Stephen Obaro; J Deeks; D Williams; L Pais; G Carlone; Richard Moxon; B Greenwood
Immune response to revaccination with meningococcal A and C polysaccharides in Gambian children following repeated immunisation during early childhood.
Vaccine 1999;17(23-24):3086-93.
1998: Stephen Obaro; Amanda Leach; K W McAdam
Use of pneumococcal polysaccharide vaccine in children.
Lancet 1998;352(9127):575.
1998: Lorenz Von Seidlein; Kalifa Bojang; P Jones; Shabbar Jaffar; Margaret Pinder; Stephen Obaro; Tom Doherty; M Haywood; Georges Snounou; B Gemperli; I Gathmann; C Royce; Keith P W J McAdam; Brian Greenwood
A randomized controlled trial of artemether/benflumetol, a new antimalarial and pyrimethamine/sulfadoxine in the treatment of uncomplicated falciparum malaria in African children.
The American journal of tropical medicine and hygiene 1998;58(5):638-44.
1998: Stephen Obaro
Effectiveness of pneumococcal vaccine.
Lancet 1998;351(9111):1284; author reply 1284-5.
1998: Kalifa Bojang; G Schneider; S Forck; Stephen Obaro; Shabbar Jaffar; Margaret Pinder; J Rowley; Brian M Greenwood
A trial of Fansidar plus chloroquine or Fansidar alone for the treatment of uncomplicated malaria in Gambian children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1998;92(1):73-6.
1998: Kalifa Bojang; Stephen Obaro; Umberto D'Alessandro; Steve Bennett; P Langerock; Geoffrey A T Targett; Brian M Greenwood
An efficacy trial of the malaria vaccine SPf66 in Gambian infants--second year of follow-up.
Vaccine 1998;16(1):62-7.
1997: Kalifa Bojang; Stephen Obaro; Amanda Leach; Umberto D'Alessandro; Steve Bennett; Wolfram G Metzger; W Ripley Ballou; Geoffrey A T Targett; Brian M Greenwood
Follow-up of Gambian children recruited to a pilot safety and immunogenicity study of the malaria vaccine SPf66.
Parasite immunology 1997;19(12):579-81.
1997: Stephen Obaro; Z Huo; Winston A S Banya; Don C Henderson; M A Monteil; Amanda Leach; Brian M Greenwood
A glycoprotein pneumococcal conjugate vaccine primes for antibody responses to a pneumococcal polysaccharide vaccine in Gambian children.
The Pediatric infectious disease journal 1997;16(12):1135-40.
1997: Shabbar Jaffar; Amanda Leach; AM Greenwood; A Jepson; O Muller; Martin O C Ota; Kalifa Bojang; Stephen Obaro; Brian M Greenwood
Changes in the pattern of infant and childhood mortality in upper river division, The Gambia, from 1989 to 1993.
Tropical medicine & international health : TM & IH 1997;2(1):28-37.
1996: Stephen Obaro; Richard A Adegbola; W A Banya; Brian M Greenwood
Carriage of pneumococci after pneumococcal vaccination.
Lancet 1996;348(9022):271-2.
1996: Stephen Obaro; M A Monteil; D C Henderson
The pneumococcal problem.
BMJ (Clinical research ed.) 1996;312(7045):1521-5.
1996: Stephen Obaro
Management of acute bacterial meningitis.
Lancet 1996;347(9000):538.
1996: Stephen Obaro
Serum, breast milk, and infant antibody after maternal immunisation with pneumococcal vaccine.
Lancet 1996;347(8995):192-3.
1996: Stephen Obaro; D C Henderson; M A Monteil
Defective antibody-mediated opsonisation of S. pneumoniae in high risk patients detected by flow cytometry.
Immunology letters 1996;49(1-2):83-9.
1995: Stephen Obaro
Epidemiology of invasive pneumococcal disease.
The Journal of infectious diseases 1995;171(4):1065-6.
1995: Stephen Obaro; D C Henderson; M Monteil
Immunity to pneumococcal infections.
Lancet 1995;345(8941):70-1.
1994: M A Monteil; D C Henderson; Stephen Obaro
Immunodeficiency without HIV. Clinical presentation vary.
BMJ (Clinical research ed.) 1994;308(6941):1436.
1994: Stephen Obaro
Measles immunisation in developing countries.
BMJ (Clinical research ed.) 1994;308(6925):411-2.
1994: Stephen Obaro; D C Henderson; M Monteil
Long term management after splenectomy. Monitor antibody levels after vaccination.
BMJ (Clinical research ed.) 1994;308(6924):338-9.
1993: J R Hobbs; Stephen Obaro
Bone marrow transplantation in sickle cell disease.
Lancet 1993;342(8883):1362-3.
1993: Stephen Obaro
Avoiding coning in childhood meningitis.
BMJ (Clinical research ed.) 1993;306(6893):1691-2.