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Michel Bouvier

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TOP 3
Michel Bouvier
Unraveling the structural basis of GPCR activation and inactivation.
Melissa Richard-Lalonde; Peter W Schiller; Rory Sleno; Mohammad Amraei; Nicolas Audet; Gianfranco Balboni; Michel Bouvier; Terence E Hébert; Mireille Hogue; Karim Nagi; Graciela Pineyro
Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors.
Michel Bouvier
[Metaphors, naming and new signaling paradigms by G-protein-coupled receptors].

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All Publications

2013: Michel Bouvier
Unraveling the structural basis of GPCR activation and inactivation.
Nature structural & molecular biology 2013;20(5):539-41.
2013: Melissa Richard-Lalonde; Peter W Schiller; Rory Sleno; Mohammad Amraei; Nicolas Audet; Gianfranco Balboni; Michel Bouvier; Terence E Hébert; Mireille Hogue; Karim Nagi; Graciela Pineyro
Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors.
Molecular pharmacology 2013;83(2):416-28.
2012: Michel Bouvier
[Metaphors, naming and new signaling paradigms by G-protein-coupled receptors].
Médecine sciences : M/S 2012;28(10):801-3.
2012: Eric Carpentier; William A Goddard; Larry A Greenbaum; Driss Rochdi; Ravinder Abrol; Daniel G Bichet; Michel Bouvier
Identification and characterization of an activating F229V substitution in the V2 vasopressin receptor in an infant with NSIAD.
Journal of the American Society of Nephrology : JASN 2012;23(10):1635-40.
2012: Khalid Hilmi; Nader Hussein; Houssam Ismail; Martine Bail; Michel Bouvier; Chantal Durette; Mohamed El-Ezzy; James L Gleason; Rodrigo Mendoza-Sanchez; Maria Johanna Rozendaal; Pierre Thibault; Sylvie Mader
Role of SUMOylation in full antiestrogenicity.
Molecular and cellular biology 2012;32(19):3823-37.
2012: Martin Audet; Michel Bouvier
Restructuring G-protein- coupled receptor activation.
Cell 2012;151(1):14-23.
2012: Geneviève Oligny-Longpré; Joris Zhou; Maithé Corbani; Gilles Guillon; Mireille Hogue; Michel Bouvier
Engagement of β-arrestin by transactivated insulin-like growth factor receptor is needed for V2 vasopressin receptor-stimulated ERK1/2 activation.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(17):E1028-37.
2012: Tarja T Leskelä; Michel Bouvier; Hiroyuki Kobayashi; Jarkko J Lackman; Miia M Vierimaa; Ulla Petaja-Repo
Cys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerization.
The Journal of biological chemistry 2012;287(7):5008-20.
2011: Wayne Stallaert; Arthur Christopoulos; Michel Bouvier
Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors.
Expert opinion on drug discovery 2011;6(8):811-25.
2010: Billy Breton; Étienne Sauvageau; Joris Zhou; Hélène Bonin; Christian Le Gouill; Michel Bouvier
Multiplexing of multicolor bioluminescence resonance energy transfer.
Biophysical journal 2010;99(12):4037-46.
2010: Patricia René; Christian Le Gouill; Irina D Pogozheva; Gary Lee; Henry I Mosberg; I Sadaf Farooqi; Kenneth J Valenzano; Michel Bouvier
Pharmacological chaperones restore function to MC4R mutants responsible for severe early-onset obesity.
The Journal of pharmacology and experimental therapeutics 2010;335(3):520-32.
2010: Billy Breton; Monique Lagace; Michel Bouvier
Combining resonance energy transfer methods reveals a complex between the alpha2A-adrenergic receptor, Galphai1beta1gamma2, and GRK2.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(12):4733-43.
2010: Manishha Patel; Yoran Margaron; Nadine Fradet; Qi Yang; Brian Wilkes; Michel Bouvier; Kay Hofmann; Jean-François Côté
An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling.
Current biology : CB 2010;20(22):2021-7.
2010: Eugénie Goupil; Danaë Tassy; Carine Bourguet; Christiane Quiniou; Veronica Wisehart; Darlaine Pétrin; Christian Le Gouill; Dominic Devost; Hans H Zingg; Michel Bouvier; H Uri Saragovi; Sylvain Chemtob; William D Lubell; Audrey Claing; Terence E Hébert; Stephane Laporte
A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway.
The Journal of biological chemistry 2010;285(33):25624-36.
2010: George Khelashvili; Kevin Dorff; Jufang Shan; Marta Camacho-Artacho; Lucy Skrabanek; Bas Vroling; Michel Bouvier; Lakshmi A Devi; Susan R George; Jonathan A Javitch; Martin J Lohse; Graeme Milligan; Richard Neubig; Krzysztof Palczewski; Marc Parmentier; Jean-Philippe Pin; Gert Vriend; Fabien Campagne; Marta Filizola
GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base.
Bioinformatics (Oxford, England) 2010;26(14):1804-5.
2010: Moulay Driss Rochdi; Gabriel A Vargas; Eric Carpentier; Geneviève Oligny-Longpré; Stanford Chen; Abraham Kovoor; Stephen E Gitelman; Stephen M Rosenthal; Mark von Zastrow; Michel Bouvier
Functional characterization of vasopressin type 2 receptor substitutions (R137H/C/L) leading to nephrogenic diabetes insipidus and nephrogenic syndrome of inappropriate antidiuresis: implications for treatments.
Molecular pharmacology 2010;77(5):836-45.
2009: L Rihakova; C Quiniou; F F Hamdan; R Kaul; S Brault; X Hou; I Lahaie; P Sapieha; D Hamel; Z Shao; F Gobeil; P Hardy; J-S Joyal; H Nedev; F Duhamel; K Beauregard; N Heveker; H U Saragovi; G Guillon; Michel Bouvier; W D Lubell; S Chemtob
VRQ397 (CRAVKY): a novel noncompetitive V2 receptor antagonist.
American journal of physiology. Regulatory, integrative and comparative physiology 2009;297(4):R1009-18.
2009: Rithwik Ramachandran; Koichiro Mihara; Maneesh Mathur; Moulay Driss Rochdi; Michel Bouvier; Kathryn DeFea; Morley D Hollenberg
Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways.
Molecular pharmacology 2009;76(4):791-801.
2009: Martin Leduc; Billy Breton; Celine Gales; Christian Le Gouill; Michel Bouvier; Sylvain Chemtob; Nikolaus Heveker
Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands.
The Journal of pharmacology and experimental therapeutics 2009;331(1):297-307.
2009: Hiroyuki Kobayashi; Koji Ogawa; Rong Yao; Olivier Lichtarge; Michel Bouvier
Functional rescue of beta-adrenoceptor dimerization and trafficking by pharmacological chaperones.
Traffic (Copenhagen, Denmark) 2009;10(8):1019-33.
2009: Sergi Ferré; Ruben Baler; Michel Bouvier; Marc G Caron; Lakshmi A Devi; Thierry Durroux; Kjell Fuxe; Susan R George; Jonathan A Javitch; Martin J Lohse; Ken Mackie; Graeme Milligan; Kevin D G Pfleger; Jean-Philippe Pin; Nora D Volkow; Maria Waldhoer; Amina S Woods; Rafael Franco
Building a new conceptual framework for receptor heteromers.
Nature chemical biology 2009;5(3):131-4.
2009: Hervé Chneiweiss; Michel Bouvier
[Médecine/Sciences as time goes by].
Médecine sciences : M/S 2009;25(1):3-4.
2008: Jun Matsubayashi; Masakatsu Takanashi; Kosuke Oikawa; K Fujita; M Tanaka; M Xu; A De Blasi; Michel Bouvier; M Kinoshita; Masahiko Kuroda; Kiyoshi Mukai
Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis.
The Journal of pathology 2008;216(3):317-27.
2008: Stephanie Pontier; Yann Percherancier; Ségolène Galandrin; Andreas Breit; Celine Gales; Michel Bouvier
Cholesterol-dependent separation of the beta2-adrenergic receptor from its partners determines signaling efficacy: insight into nanoscale organization of signal transduction.
The Journal of biological chemistry 2008;283(36):24659-72.
2008: Martin Audet; Michel Bouvier
Insights into signaling from the beta2-adrenergic receptor structure.
Nature chemical biology 2008;4(7):397-403.
2008: Ségolène Galandrin; Geneviève Oligny-Longpré; Hélène Bonin; Koji Ogawa; Celine Gales; Michel Bouvier
Conformational rearrangements and signaling cascades involved in ligand-biased mitogen-activated protein kinase signaling through the beta1-adrenergic receptor.
Molecular pharmacology 2008;74(1):162-72.
2008: Nicolas Audet; Celine Gales; Elodie Archer-Lahlou; Marc Vallières; Peter W Schiller; Michel Bouvier; Graciela Pineyro
Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins.
The Journal of biological chemistry 2008;283(22):15078-88.
2008: Moussa Ouedraogo; Sandra Lecat; Moulay Driss Rochdi; Muriel Hachet-Haas; Hans Matthes; Hervé Gicquiaux; Sophie Verrier; Mireille Gaire; Nicole Glasser; Yves Mély; Kenneth Takeda; Michel Bouvier; Jean-Luc Galzi; Bernard Bucher
Distinct motifs of neuropeptide Y receptors differentially regulate trafficking and desensitization.
Traffic (Copenhagen, Denmark) 2008;9(3):305-24.
2008: Vincent Coulon; Martin Audet; Vincent Homburger; Joël Bockaert; Laurent Fagni; Michel Bouvier; Julie Perroy
Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer.
Biophysical journal 2008;94(3):1001-9.
2007: Celine Gales; Michel Bouvier
[New talk between receptor and trimeric G proteins: "an intertwined body dance"].
Médecine sciences : M/S 2007;23(11):1031-4.
2007: Madeleine Héroux; Mireille Hogue; Sébastien Lemieux; Michel Bouvier
Functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of receptor activity-modifying protein-1.
The Journal of biological chemistry 2007;282(43):31610-20.
2007: E Stefan; S Aquin; N Berger; C R Landry; Beat Nyfeler; Michel Bouvier; Stephen W Michnick
Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(43):16916-21.
2007: Fadi F Hamdan; Moulay Driss Rochdi; Billy Breton; Delphine Fessart; Douce E Michaud; Pascale G Charest; Stephane Laporte; Michel Bouvier
Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between beta-arrestins and AP-2.
The Journal of biological chemistry 2007;282(40):29089-100.
2007: Ségolène Galandrin; Geneviève Oligny-Longpré; Michel Bouvier
The evasive nature of drug efficacy: implications for drug discovery.
Trends in pharmacological sciences 2007;28(8):423-30.
2007: Stefano Marullo; Michel Bouvier
Resonance energy transfer approaches in molecular pharmacology and beyond.
Trends in pharmacological sciences 2007;28(8):362-5.
2007: Madeleine Héroux; Billy Breton; Mireille Hogue; Michel Bouvier
Assembly and signaling of CRLR and RAMP1 complexes assessed by BRET.
Biochemistry 2007;46(23):7022-33.
2007: Delphine Fessart; May Simaan; Brandon Zimmerman; Jonathan W D Comeau; Fadi F Hamdan; Paul Wiseman; Michel Bouvier; Stephane Laporte
Src-dependent phosphorylation of beta2-adaptin dissociates the beta-arrestin-AP-2 complex.
Journal of cell science 2007;120(Pt 10):1723-32.
2007: Damien Boeglin; Fadi F Hamdan; Rosa E Melendez; Jérôme Cluzeau; Andre Laperriere; Madeleine Héroux; Michel Bouvier; William D Lubell
Calcitonin gene-related peptide analogues with aza and indolizidinone amino acid residues reveal conformational requirements for antagonist activity at the human calcitonin gene-related peptide 1 receptor.
Journal of medicinal chemistry 2007;50(6):1401-8.
2007: Michel Bouvier
When an inhibitor promotes activity.
Chemistry & biology 2007;14(3):241-2.
2007: Michel Bouvier
[Will academic research rescue the drug discovery crisis?].
Médecine sciences : M/S 2007;23(3):227-8.
2007: Jean-Philippe Pin; Richard Neubig; Michel Bouvier; Lakshmi Devi; Marta Filizola; Jonathan A Javitch; Martin J Lohse; Graeme Milligan; Krzysztof Palczewski; Marc Parmentier; Michael Spedding
International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers.
Pharmacological reviews 2007;59(1):5-13.
2007: Lucy Skrabanek; Marta Murcia; Michel Bouvier; Lakshmi Devi; Susan R George; Martin J Lohse; Graeme Milligan; Richard Neubig; Krzysztof Palczewski; Marc Parmentier; Jean-Philippe Pin; Gert Vriend; Jonathan A Javitch; Fabien Campagne; Marta Filizola
Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base.
BMC bioinformatics 2007;8():177.
2007: Michel Bouvier; Nikolaus Heveker; Ralf JOckers; Stefano Marullo; Graeme Milligan
BRET analysis of GPCR oligomerization: newer does not mean better.
Nature methods 2007;4(1):3-4; author reply 4.
2007: Pascale G Charest; Geneviève Oligny-Longpré; Hélène Bonin; Mounia Azzi; Michel Bouvier
The V2 vasopressin receptor stimulates ERK1/2 activity independently of heterotrimeric G protein signalling.
Cellular signalling 2007;19(1):32-41.
2006: Ségolène Galandrin; Michel Bouvier
Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy.
Molecular pharmacology 2006;70(5):1575-84.
2006: Celine Gales; Joost J J Van Durm; Stéphane Schaak; Stephanie Pontier; Yann Percherancier; Martin Audet; Hervé Paris; Michel Bouvier
Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes.
Nature structural & molecular biology 2006;13(9):778-86.
2006: Michel Bouvier
An interview with Michel Bouvier, Ph.D. Interview by Vicki Glaser.
Assay and drug development technologies 2006;4(4):365-71.
2006: Andreas Breit; Khatuna Gagnidze; Lakshmi A Devi; Monique Lagace; Michel Bouvier
Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling.
Molecular pharmacology 2006;70(2):686-96.
2006: R Victor Rebois; Mélanie Robitaille; Celine Gales; Denis J Dupré; Alessandra Baragli; Phan Trieu; Nathalie Ethier; Michel Bouvier; Terence E Hébert
Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells.
Journal of cell science 2006;119(Pt 13):2807-18.
2006: Stephanie Pontier; Nicolas Lahaie; Rachel Ginham; Fannie St-Gelais; Hélène Bonin; David J Bell; Helen Flynn; Louis-Eric Trudeau; Jeffrey McIlhinney; Julia H White; Michel Bouvier
Coordinated action of NSF and PKC regulates GABAB receptor signaling efficacy.
The EMBO journal 2006;25(12):2698-709.
2006: Ulla Petaja-Repo; Mireille Hogue; Tarja T Leskelä; Piia M H Markkanen; Jussi T Tuusa; Michel Bouvier
Distinct subcellular localization for constitutive and agonist-modulated palmitoylation of the human delta opioid receptor.
The Journal of biological chemistry 2006;281(23):15780-9.
2006: Fadi F Hamdan; Yann Percherancier; Billy Breton; Michel Bouvier
Monitoring protein-protein interactions in living cells by bioluminescence resonance energy transfer (BRET).
Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] 2006;Chapter 5():Unit 5.23.
2006: Michel Bouvier; Gérard Friedlander
[To apprehend the complexity of living at the era of the << Omics >>].
Médecine sciences : M/S 2006;22(1):3-4.
2006: Demian Barbas; Jacques P Zappulla; Stéphane Angers; Michel Bouvier; Habib A Mohamed; John H Byrne; Vincent F Castellucci; Luc DesGroseillers
An aplysia dopamine1-like receptor: molecular and functional characterization.
Journal of neurochemistry 2006;96(2):414-27.
2006: Virginie Bernier; Jean-Pierre Morello; Alexandro Zarruk; Nicolas Debrand; Ali Salahpour; Michèle Lonergan; Marie-Françoise Arthus; André Laperrière; Rémi Brouard; Michel Bouvier; Daniel G Bichet
Pharmacologic chaperones as a potential treatment for X-linked nephrogenic diabetes insipidus.
Journal of the American Society of Nephrology : JASN 2006;17(1):232-43.
2005: Hélène Storez; Mark SCOTT; Hassan Issafras; Anne Burtey; Alexandre Benmerah; Olivier Muntaner; Tristan Piolot; Marc Tramier; Maïté Coppey-Moisan; Michel Bouvier; CATHERINE LABBE-JULLIE; Stefano Marullo
Homo- and hetero-oligomerization of beta-arrestins in living cells.
The Journal of biological chemistry 2005;280(48):40210-5.
2005: Kimberly Hu; Jean-François Clément; Levon Abrahamyan; Klaus Strebel; Michel Bouvier; Lawrence Kleiman; Andrew J Mouland
A human immunodeficiency virus type 1 protease biosensor assay using bioluminescence resonance energy transfer.
Journal of virological methods 2005;128(1-2):93-103.
2005: Wei-Zhong Zhu; Khalid Chakir; Shengjun Zhang; Dongmei Yang; Catherine Lavoie; Michel Bouvier; Terence E Hébert; Edward G Lakatta; Heping Cheng; Rui-Ping Xiao
Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility.
Circulation research 2005;97(3):244-51.
2005: Fadi F Hamdan; Martin Audet; Philippe Garneau; Jerry Pelletier; Michel Bouvier
High-throughput screening of G protein-coupled receptor antagonists using a bioluminescence resonance energy transfer 1-based beta-arrestin2 recruitment assay.
Journal of biomolecular screening 2005;10(5):463-75.
2005: Graeme Milligan; Michel Bouvier
Methods to monitor the quaternary structure of G protein-coupled receptors.
The FEBS journal 2005;272(12):2914-25.
2005: Eneko Urizar; Lucia Montanelli; Tiffany Loy; Marco Bonomi; Stéphane Swillens; Celine Gales; Michel Bouvier; Guillaume Smits; Gilbert Vassart; Sabine Costagliola
Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity.
The EMBO journal 2005;24(11):1954-64.
2005: Josée-France Villemure; Lynda Adam; Nicola J Bevan; Katy Gearing; Sebastien Chenier; Michel Bouvier
Subcellular distribution of GABA(B) receptor homo- and hetero-dimers.
The Biochemical journal 2005;388(Pt 1):47-55.
2005: Pascale G Charest; Sonia Terrillon; Michel Bouvier
Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET.
EMBO reports 2005;6(4):334-40.
2005: Yann Percherancier; Yamina A Berchiche; Isabelle Slight; Rudolf Volkmer-Engert; Hirokazu Tamamura; Nobutaka Fujii; Michel Bouvier; Nikolaus Heveker
Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers.
The Journal of biological chemistry 2005;280(11):9895-903.
2005: Celine Gales; R Victor Rebois; Mireille Hogue; Phan Trieu; Andreas Breit; Terence E Hébert; Michel Bouvier
Real-time monitoring of receptor and G-protein interactions in living cells.
Nature methods 2005;2(3):177-84.
2005: Sébastien Bulenger; Stefano Marullo; Michel Bouvier
Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation.
Trends in pharmacological sciences 2005;26(3):131-7.
2005: Graciela Piñeyro; Mounia Azzi; André deLéan; Peter W Schiller; Michel Bouvier
Reciprocal regulation of agonist and inverse agonist signaling efficacy upon short-term treatment of the human delta-opioid receptor with an inverse agonist.
Molecular pharmacology 2005;67(1):336-48.
2004: Sébastien Granier; Sonia Terrillon; Robert Pascal; Hélène Déméné; Michel Bouvier; Gilles Guillon; Christiane Mendre
A cyclic peptide mimicking the third intracellular loop of the V2 vasopressin receptor inhibits signaling through its interaction with receptor dimer and G protein.
The Journal of biological chemistry 2004;279(49):50904-14.
2004: Julie Perroy; Stephanie Pontier; Pascale G Charest; Muriel Aubry; Michel Bouvier
Real-time monitoring of ubiquitination in living cells by BRET.
Nature methods 2004;1(3):203-8.
2004: Sonia Terrillon; Michel Bouvier
Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes.
The EMBO journal 2004;23(20):3950-61.
2004: Virginie Bernier; Daniel G Bichet; Michel Bouvier
Pharmacological chaperone action on G-protein-coupled receptors.
Current opinion in pharmacology 2004;4(5):528-33.
2004: Maxime Denis; Bassam Haidar; Michel Marcil; Michel Bouvier; Larbi Krimbou; Jacques Genest
Characterization of oligomeric human ATP binding cassette transporter A1. Potential implications for determining the structure of nascent high density lipoprotein particles.
The Journal of biological chemistry 2004;279(40):41529-36.
2004: Riad Qanbar; Michel Bouvier
Determination of protein-bound palmitate turnover rates using a three-compartment model that formally incorporates [3H]palmitate recycling.
Biochemistry 2004;43(38):12275-88.
2004: Marilyn Registre; Jacky G Goetz; Pascal St Pierre; Hao Pang; Monique Lagace; Michel Bouvier; Phuong U Le; Ivan R Nabi
The gene product of the gp78/AMFR ubiquitin E3 ligase cDNA is selectively recognized by the 3F3A antibody within a subdomain of the endoplasmic reticulum.
Biochemical and biophysical research communications 2004;320(4):1316-22.
2004: Ali Salahpour; Stéphane Angers; Jean-François Mercier; Monique Lagace; Stefano Marullo; Michel Bouvier
Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting.
The Journal of biological chemistry 2004;279(32):33390-7.
2004: Virginie Bernier; Monique Lagace; Michèle Lonergan; Marie-Françoise Arthus; Daniel G Bichet; Michel Bouvier
Functional rescue of the constitutively internalized V2 vasopressin receptor mutant R137H by the pharmacological chaperone action of SR49059.
Molecular endocrinology (Baltimore, Md.) 2004;18(8):2074-84.
2004: Andreas Breit; Monique Lagace; Michel Bouvier
Hetero-oligomerization between beta2- and beta3-adrenergic receptors generates a beta-adrenergic signaling unit with distinct functional properties.
The Journal of biological chemistry 2004;279(27):28756-65.
2004: Virginie Bernier; Monique Lagace; Daniel G Bichet; Michel Bouvier
Pharmacological chaperones: potential treatment for conformational diseases.
Trends in endocrinology and metabolism: TEM 2004;15(5):222-8.
2004: Sergi Ferré; Francisco Ciruela; Meritxell Canals; Daniel Marcellino; Javier Burgueno; Vicent Casadó; Joelle Hillion; Maria Torvinen; Francesca Fanelli; Piero de Benedetti Pd; Steven R Goldberg; Michel Bouvier; Kjell Fuxe; Luigi F Agnati; Carmen Lluis; Rafael Franco; Amina S Woods
Adenosine A2A-dopamine D2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders.
Parkinsonism & related disorders 2004;10(5):265-71.
2004: Maxime Denis; Bassam Haidar; Michel Marcil; Michel Bouvier; Larbi Krimbou; Jacques Genest
Molecular and cellular physiology of apolipoprotein A-I lipidation by the ATP-binding cassette transporter A1 (ABCA1).
The Journal of biological chemistry 2004;279(9):7384-94.
2004: Sonia Terrillon; Claude Barberis; Michel Bouvier
Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(6):1548-53.
2004: Meritxell Canals; Javier Burgueño; Daniel Marcellino; Nuria Cabello; Enric Isidre Canela; Josefa Mallol; Luigi F Agnati; Sergi Ferré; Michel Bouvier; Kjell Fuxe; Francisco Ciruela; Carmen Lluis; Rafael Franco
Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer.
Journal of neurochemistry 2004;88(3):726-34.
2004: Sonia Terrillon; Michel Bouvier
Roles of G-protein-coupled receptor dimerization.
EMBO reports 2004;5(1):30-4.
2004: Ajamete Kaykas; Julia Yang-Snyder; Madeleine Héroux; Kavita V Shah; Michel Bouvier; Randall T Moon
Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization.
Nature cell biology 2004;6(1):52-8.
2003: Meritxell Canals; Daniel Marcellino; Francesca Fanelli; Francisco Ciruela; Piero de Benedetti; Steven R Goldberg; Kim A Neve; Kjell Fuxe; Luigi F Agnati; Amina S Woods; Sergi Ferré; Carmen Lluis; Michel Bouvier; Rafael Franco
Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer.
The Journal of biological chemistry 2003;278(47):46741-9.
2003: Pascale G Charest; Michel Bouvier
Palmitoylation of the V2 vasopressin receptor carboxyl tail enhances beta-arrestin recruitment leading to efficient receptor endocytosis and ERK1/2 activation.
The Journal of biological chemistry 2003;278(42):41541-51.
2003: Mounia Azzi; Pascale G Charest; Stéphane Angers; Guy Rousseau; Trudy Kohout; Michel Bouvier; Graciela Piñeyro
Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11406-11.
2003: Julie Perroy; Lynda Adam; Riad Qanbar; Sebastien Chenier; Michel Bouvier
Phosphorylation-independent desensitization of GABA(B) receptor by GRK4.
The EMBO journal 2003;22(15):3816-24.
2003: Delphine Germain-Desprez; Martine Bazinet; Michel Bouvier; Muriel Aubry
Oligomerization of transcriptional intermediary factor 1 regulators and interaction with ZNF74 nuclear matrix protein revealed by bioluminescence resonance energy transfer in living cells.
The Journal of biological chemistry 2003;278(25):22367-73.
2003: Maxime Denis; Rachel Bissonnette; Bassam Haidar; Larbi Krimbou; Michel Bouvier; Jacques Genest
Expression, regulation, and activity of ABCA1 in human cell lines.
Molecular genetics and metabolism 2003;78(4):265-74.
2003: Sonia Terrillon; Thierry Durroux; Bernard Mouillac; Andreas Breit; Mohammed A Ayoub; Magali Taulan; Ralf JOckers; Claude Barberis; Michel Bouvier
Oxytocin and vasopressin V1a and V2 receptors form constitutive homo- and heterodimers during biosynthesis.
Molecular endocrinology (Baltimore, Md.) 2003;17(4):677-91.
2003: Ali Salahpour; Hélène Bonin; Suparna Bhalla; Ulla Petaja-Repo; Michel Bouvier
Biochemical characterization of beta2-adrenergic receptor dimers and oligomers.
Biological chemistry 2003;384(1):117-23.
2003: Riad Qanbar; Michel Bouvier
Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function.
Pharmacology & therapeutics 2003;97(1):1-33.
2002: Natalie Lavine; Nathalie Ethier; James N Oak; Lin Pei; Fang Liu; Phan Trieu; R Victor Rebois; Michel Bouvier; Terence E Hebert; Hubert H M Van Tol
G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase.
The Journal of biological chemistry 2002;277(48):46010-9.
2002: Jean-François Mercier; Ali Salahpour; Stéphane Angers; Andreas Breit; Michel Bouvier
Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer.
The Journal of biological chemistry 2002;277(47):44925-31.
2002: Catherine Lavoie; Jean-François Mercier; Ali Salahpour; Dhiviya Umapathy; Andreas Breit; Louis Villeneuve; Wei-Zhong Zhu; Rui-Ping Xiao; Edward G Lakatta; Michel Bouvier; Terence E Hébert
Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy.
The Journal of biological chemistry 2002;277(38):35402-10.
2002: Hassan Issafras; Stéphane Angers; Sébastien Bulenger; Cédric Blanpain; Marc Parmentier; CATHERINE LABBE-JULLIE; Michel Bouvier; Stefano Marullo
Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors.
The Journal of biological chemistry 2002;277(38):34666-73.
2002: Mohammed A Ayoub; Cyril Couturier; Estelle Lucas-Meunier; Stéphane Angers; Philippe Fossier; Michel Bouvier; Ralf JOckers
Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer.
The Journal of biological chemistry 2002;277(24):21522-8.
2002: Ulla Petaja-Repo; Mireille Hogue; Suparna Bhalla; André Laperrière; Jean-Pierre Morello; Michel Bouvier
Ligands act as pharmacological chaperones and increase the efficiency of delta opioid receptor maturation.
The EMBO journal 2002;21(7):1628-37.
2002: Lucie Bertrand; Stéphane Parent; Mireille Caron; Mireille Legault; Erik Joly; Stéphane Angers; Michel Bouvier; Mike Brown; Benoit Houle; Luc Ménard
The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS).
Journal of receptor and signal transduction research 2002;22(1-4):533-41.
2002: Demian Barbas; Jacques P Zappulla; Stéphane Angers; Michel Bouvier; Vincent F Castellucci; Luc DesGroseillers
Functional characterization of a novel serotonin receptor (5-HTap2) expressed in the CNS of Aplysia californica.
Journal of neurochemistry 2002;80(2):335-45.
2002: Stéphane Angers; Ali Salahpour; Michel Bouvier
Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function.
Annual review of pharmacology and toxicology 2002;42():409-35.
2001: S Hilairet; C Bélanger; Johanne Bertrand; André Laperrière; Steven M Foord; Michel Bouvier
Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin.
The Journal of biological chemistry 2001;276(45):42182-90.
2001: Mounia Azzi; Graciela Piñeyro; Stephanie Pontier; S Parent; Herve Ansanay; Michel Bouvier
Allosteric effects of G protein overexpression on the binding of beta-adrenergic ligands with distinct inverse efficacies.
Molecular pharmacology 2001;60(5):999-1007.
2001: Eric Carpentier; D Lebesgue; Amine Kamen; M Hogue; Michel Bouvier; Yves Durocher
Increased production of active human beta(2)-adrenergic/G(alphas) fusion receptor in Sf-9 cells using nutrient limiting conditions.
Protein expression and purification 2001;23(1):66-74.
2001: Graciela Piñeyro; Mounia Azzi; André De Léan; P Schiller; Michel Bouvier
Short-term inverse-agonist treatment induces reciprocal changes in delta-opioid agonist and inverse-agonist binding capacity.
Molecular pharmacology 2001;60(4):816-27.
2001: S Hilairet; Steven M Foord; Fiona Marshall; Michel Bouvier
Protein-protein interaction and not glycosylation determines the binding selectivity of heterodimers between the calcitonin receptor-like receptor and the receptor activity-modifying proteins.
The Journal of biological chemistry 2001;276(31):29575-81.
2001: Guy Rousseau; Pierre S Haddad; N Gallo-Payet; Michel Bouvier
Ca(2+)-dependent sensitization of adenylyl cyclase activity.
European journal of pharmacology 2001;422(1-3):53-60.
2001: C Bélanger; Herve Ansanay; Riad Qanbar; Michel Bouvier
Primary sequence requirements for S-acylation of beta(2)-adrenergic receptor peptides.
FEBS letters 2001;499(1-2):59-64.
2001: Jean-Pierre Morello; Ali Salahpour; Ulla Petaja-Repo; André Laperrière; Michèle Lonergan; Marie-Françoise Arthus; Ivan R Nabi; Daniel G Bichet; Michel Bouvier
Association of calnexin with wild type and mutant AVPR2 that causes nephrogenic diabetes insipidus.
Biochemistry 2001;40(23):6766-75.
2001: Stéphane Angers; Ali Salahpour; Michel Bouvier
Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells.
Life sciences 2001;68(19-20):2243-50.
2001: Michel Bouvier
Oligomerization of G-protein-coupled transmitter receptors.
Nature reviews. Neuroscience 2001;2(4):274-86.
2001: Ulla Petaja-Repo; Mireille Hogue; Andre Laperriere; Suparna Bhalla; P Walker; Michel Bouvier
Newly synthesized human delta opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the cytosol, deglycosylated, ubiquitinated, and degraded by the proteasome.
The Journal of biological chemistry 2001;276(6):4416-23.
2001: C E Laurent; René Cardinal; Guy Rousseau; Michel Vermeulen; Caroline Bouchard; M Wilkinson; J Andrew Armour; Michel Bouvier
Functional desensitization to isoproterenol without reducing cAMP production in canine failing cardiocytes.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(2):R355-64.
2001: S Moffett; Guy Rousseau; Monique Lagace; Michel Bouvier
The palmitoylation state of the beta(2)-adrenergic receptor regulates the synergistic action of cyclic AMP-dependent protein kinase and beta-adrenergic receptor kinase involved in its phosphorylation and desensitization.
Journal of neurochemistry 2001;76(1):269-79.
2000: Jean-Pierre Morello; Ulla Petaja-Repo; Daniel G Bichet; Michel Bouvier
Pharmacological chaperones: a new twist on receptor folding.
Trends in pharmacological sciences 2000;21(12):466-9.
2000: Ali Salahpour; Stéphane Angers; Michel Bouvier
Functional significance of oligomerization of G-protein-coupled receptors.
Trends in endocrinology and metabolism: TEM 2000;11(5):163-8.
2000: Ulla Petaja-Repo; Mireille Hogue; Andre Laperriere; P Walker; Michel Bouvier
Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human delta opioid receptor.
The Journal of biological chemistry 2000;275(18):13727-36.
2000: Jean-Pierre Morello; Ali Salahpour; André Laperrière; Virginie Bernier; Marie-Françoise Arthus; Michèle Lonergan; Ulla Petaja-Repo; Stéphane Angers; Didier Morin; Daniel G Bichet; Michel Bouvier
Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants.
The Journal of clinical investigation 2000;105(7):887-95.
2000: Stéphane Angers; Ali Salahpour; Erik Joly; S Hilairet; D Chelsky; M Dennis; Michel Bouvier
Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET).
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3684-9.
1999: TP Loisel; Herve Ansanay; Lynda Adam; Stefano Marullo; R Seifert; Monique Lagace; Michel Bouvier
Activation of the beta(2)-adrenergic receptor-Galpha(s) complex leads to rapid depalmitoylation and inhibition of repalmitoylation of both the receptor and Galpha(s).
The Journal of biological chemistry 1999;274(43):31014-9.
1999: Ralf JOckers; Stéphane Angers; A Da Silva; P Benaroch; A Donny Strosberg; Michel Bouvier; Stefano Marullo
Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis.
The Journal of biological chemistry 1999;274(41):28900-8.
1999: Lynda Adam; Michel Bouvier; T L Jones
Nitric oxide modulates beta(2)-adrenergic receptor palmitoylation and signaling.
The Journal of biological chemistry 1999;274(37):26337-43.
1999: M Marquis; R Fenrick; L Pedro; Michel Bouvier; André De Léan
Comparative binding study of rat natriuretic peptide receptor-A.
Molecular and cellular biochemistry 1999;194(1-2):23-30.
1998: Terence E Hebert; TP Loisel; Lynda Adam; Nathalie Ethier; S S Onge; Michel Bouvier
Functional rescue of a constitutively desensitized beta2AR through receptor dimerization.
The Biochemical journal 1998;330 ( Pt 1)():287-93.
1998: Michel Bouvier; Guy Rousseau
Subtype-specific regulation of the beta-adrenergic receptors.
Advances in pharmacology (San Diego, Calif.) 1998;42():433-8.
1997: André Lacroix; Johanne Tremblay; Guy Rousseau; Michel Bouvier; Pavel Hamet
Propranolol therapy for ectopic beta-adrenergic receptors in adrenal Cushing's syndrome.
The New England journal of medicine 1997;337(20):1429-34.
1997: TP Loisel; Herve Ansanay; S St-Onge; Bernard Gay; Pierre Boulanger; A Donny Strosberg; Stefano Marullo; Michel Bouvier
Recovery of homogeneous and functional beta 2-adrenergic receptors from extracellular baculovirus particles.
Nature biotechnology 1997;15(12):1300-4.
1997: René J L Murphy; Phillip F Gardiner; Guy Rousseau; Michel Bouvier; Louise Béliveau
Chronic beta-blockade increases skeletal muscle beta-adrenergic-receptor density and enhances contractile force.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;83(2):459-65.
1997: Guy Rousseau; N Guilbault; A Da Silva; B Mouillac; P Chidiac; Michel Bouvier
Influence of receptor density on the patterns of beta2-adrenocepter desensitization.
European journal of pharmacology 1997;326(1):75-84.
1996: T P Loisel; Lynda Adam; Terence E Hebert; Michel Bouvier
Agonist stimulation increases the turnover rate of beta 2AR-bound palmitate and promotes receptor depalmitoylation.
Biochemistry 1996;35(49):15923-32.
1996: P Chidiac; S Nouet; Michel Bouvier
Agonist-induced modulation of inverse agonist efficacy at the beta 2-adrenergic receptor.
Molecular pharmacology 1996;50(3):662-9.
1996: S Moffett; Lynda Adam; H Bonin; T P Loisel; Michel Bouvier; B Mouillac
Palmitoylated cysteine 341 modulates phosphorylation of the beta2-adrenergic receptor by the cAMP-dependent protein kinase.
The Journal of biological chemistry 1996;271(35):21490-7.
1996: Terence E Hebert; S Moffett; J P Morello; T P Loisel; Daniel G Bichet; C Barret; Michel Bouvier
A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.
The Journal of biological chemistry 1996;271(27):16384-92.
1996: Guy Rousseau; F Nantel; Michel Bouvier
Distinct receptor domains determine subtype-specific coupling and desensitization phenotypes for human beta1- and beta2-adrenergic receptors.
Molecular pharmacology 1996;49(4):752-60.
1995: M Valiquette; S Parent; T P Loisel; Michel Bouvier
Mutation of tyrosine-141 inhibits insulin-promoted tyrosine phosphorylation and increased responsiveness of the human beta 2-adrenergic receptor.
The EMBO journal 1995;14(22):5542-9.
1995: Michel Bouvier; T P Loisel; Terence E Hebert
Dynamic regulation of G-protein coupled receptor palmitoylation: potential role in receptor function.
Biochemical Society transactions 1995;23(3):577-81.
1995: F Nantel; Michel Bouvier; A D Strosberg; Stefano Marullo
Functional effects of long-term activation on human beta 2- and beta 3-adrenoceptor signalling.
British journal of pharmacology 1995;114(5):1045-51.
1995: Stefano Marullo; F Nantel; A D Strosberg; Michel Bouvier
Variability in the regulation of beta-adrenoceptor subtypes.
Biochemical Society transactions 1995;23(1):126-9.
1995: Michel Bouvier; S Moffett; T P Loisel; B Mouillac; Terence E Hebert; P Chidiac
Palmitoylation of G-protein-coupled receptors: a dynamic modification with functional consequences.
Biochemical Society transactions 1995;23(1):116-20.
1995: Michel Bouvier; P Chidiac; Terence E Hebert; T P Loisel; S Moffett; B Mouillac
Dynamic palmitoylation of G-protein-coupled receptors in eukaryotic cells.
Methods in enzymology 1995;250():300-14.
1994: S St-Onge; P Chidiac; Léa Brakier-Gingras; Michel Bouvier
Beta-adrenergic receptor desensitization in the early stage of hereditary cardiomyopathy in hamsters.
Canadian journal of physiology and pharmacology 1994;72(8):875-83.
1994: F Nantel; Stefano Marullo; S Krief; A D Strosberg; Michel Bouvier
Cell-specific down-regulation of the beta 3-adrenergic receptor.
The Journal of biological chemistry 1994;269(18):13148-55.
1994: Jacques de Champlain; A Yacine; R Le Blanc; Michel Bouvier; R Lebeau; Réginald Nadeau
Effects of trandolapril on the sympathetic tone and reactivity in systemic hypertension.
The American journal of cardiology 1994;73(10):18C-25C.
1994: P Chidiac; Terence E Hebert; M Valiquette; M Dennis; Michel Bouvier
Inverse agonist activity of beta-adrenergic antagonists.
Molecular pharmacology 1994;45(3):490-9.
1993: T Suzuki; F Nantel; H Bonin; M Valiquette; Michel Bouvier
Cellular characterization of the pharmacological selectivity and tachyphylactic properties of denopamine for the human beta adrenergic receptors.
The Journal of pharmacology and experimental therapeutics 1993;267(2):785-90.
1993: M Valiquette; H Bonin; Michel Bouvier
Mutation of tyrosine-350 impairs the coupling of the beta 2-adrenergic receptor to the stimulatory guanine nucleotide binding protein without interfering with receptor down-regulation.
Biochemistry 1993;32(19):4979-85.
1993: F Nantel; H Bonin; L J Emorine; Vladimir Zilberfarb; A D Strosberg; Michel Bouvier; Stefano Marullo
The human beta 3-adrenergic receptor is resistant to short term agonist-promoted desensitization.
Molecular pharmacology 1993;43(4):548-55.
1993: S Moffett; B Mouillac; H Bonin; Michel Bouvier
Altered phosphorylation and desensitization patterns of a human beta 2-adrenergic receptor lacking the palmitoylated Cys341.
The EMBO journal 1993;12(1):349-56.
1992: B Mouillac; M Caron; H Bonin; M Dennis; Michel Bouvier
Agonist-modulated palmitoylation of beta 2-adrenergic receptor in Sf9 cells.
The Journal of biological chemistry 1992;267(30):21733-7.
1992: T Suzuki; C T Nguyen; F Nantel; H Bonin; M Valiquette; T Frielle; Michel Bouvier
Distinct regulation of beta 1- and beta 2-adrenergic receptors in Chinese hamster fibroblasts.
Molecular pharmacology 1992;41(3):542-8.
1991: A Calderone; Michel Bouvier; K Li; C Juneau; Jacques de Champlain; Jean-Lucien Rouleau
Dysfunction of the beta- and alpha-adrenergic systems in a model of congestive heart failure. The pacing-overdrive dog.
Circulation research 1991;69(2):332-43.
1991: Michel Bouvier; N Guilbault; H Bonin
Phorbol-ester-induced phosphorylation of the beta 2-adrenergic receptor decreases its coupling to Gs.
FEBS letters 1991;279(2):243-8.
1990: Sheila Collins; Michel Bouvier; M J Lohse; J L Benovic; Marc G Caron; R J Lefkowitz
Mechanisms involved in adrenergic receptor desensitization.
Biochemical Society transactions 1990;18(4):541-4.
1990: M Valiquette; H Bonin; M Hnatowich; Marc G Caron; R J Lefkowitz; Michel Bouvier
Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptor.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):5089-93.
1990: W P Hausdorff; M J Lohse; Michel Bouvier; Stephen B Liggett; Marc G Caron; R J Lefkowitz
Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor.
Symposia of the Society for Experimental Biology 1990;44():225-40.
1989: Stephen B Liggett; Michel Bouvier; B F O'Dowd; Marc G Caron; R J Lefkowitz; A DeBlasi
Substitution of an extracellular cysteine in the beta 2-adrenergic receptor enhances agonist-promoted phosphorylation and receptor desensitization.
Biochemical and biophysical research communications 1989;165(1):257-63.
1989: Michel Bouvier; Sheila Collins; B F O'Dowd; P T Campbell; A de Blasi; B K Kobilka; C MacGregor; G P Irons; Marc G Caron; R J Lefkowitz
Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level.
The Journal of biological chemistry 1989;264(28):16786-92.
1989: Stephen B Liggett; Michel Bouvier; W P Hausdorff; B O'Dowd; Marc G Caron; R J Lefkowitz
Altered patterns of agonist-stimulated cAMP accumulation in cells expressing mutant beta 2-adrenergic receptors lacking phosphorylation sites.
Molecular pharmacology 1989;36(4):641-6.
1989: Jacques de Champlain; H Eid; G Drolet; Michel Bouvier; S Foucart
Peripheral neurogenic mechanisms in deoxycorticosterone acetate--salt hypertension in the rat.
Canadian journal of physiology and pharmacology 1989;67(9):1140-5.
1989: W P Hausdorff; Michel Bouvier; B F O'Dowd; G P Irons; Marc G Caron; R J Lefkowitz
Phosphorylation sites on two domains of the beta 2-adrenergic receptor are involved in distinct pathways of receptor desensitization.
The Journal of biological chemistry 1989;264(21):12657-65.
1989: Sheila Collins; Michel Bouvier; M A Bolanowski; Marc G Caron; R J Lefkowitz
cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(13):4853-7.
1989: B F O'Dowd; M Hnatowich; Marc G Caron; R J Lefkowitz; Michel Bouvier
Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor.
The Journal of biological chemistry 1989;264(13):7564-9.
1989: G Drolet; Michel Bouvier; Jacques de Champlain
Enhanced sympathoadrenal reactivity to haemorrhagic stress in DOCA-salt hypertensive rats.
Journal of hypertension 1989;7(3):237-42.
1988: Michel Bouvier; W P Hausdorff; A De Blasi; B F O'Dowd; B K Kobilka; Marc G Caron; R J Lefkowitz
Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization.
Nature 1988;333(6171):370-3.
1988: Michel Bouvier; M Hnatowich; Sheila Collins; B K Kobilka; A Deblasi; R J Lefkowitz; Marc G Caron
Expression of a human cDNA encoding the beta 2-adrenergic receptor in Chinese hamster fibroblasts (CHW): functionality and regulation of the expressed receptors.
Molecular pharmacology 1988;33(2):133-9.
1988: R J Lefkowitz; B K Kobilka; J L Benovic; Michel Bouvier; S Cotecchia; W P Hausdorff; Henrik G Dohlman; John W Regan; Marc G Caron
Molecular biology of adrenergic receptors.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():507-14.
1988: J L Benovic; Michel Bouvier; Marc G Caron; R J Lefkowitz
Regulation of adenylyl cyclase-coupled beta-adrenergic receptors.
Annual review of cell biology 1988;4():405-28.
1987: Henrik G Dohlman; Michel Bouvier; J L Benovic; Marc G Caron; R J Lefkowitz
The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis.
The Journal of biological chemistry 1987;262(29):14282-8.
1987: Michel Bouvier; L Farley; J de Champlain
Red blood cell catecholamine levels in normotensive and DOCA-salt hypertensive rats.
The American journal of physiology 1987;253(2 Pt 2):H270-5.
1987: Jacques de Champlain; Michel Bouvier; G Drolet
Abnormal regulation of the sympathoadrenal system in deoxycorticosterone acetate-salt hypertensive rats.
Canadian journal of physiology and pharmacology 1987;65(8):1605-14.
1987: T Yoshimasa; David R Sibley; Michel Bouvier; R J Lefkowitz; Marc G Caron
Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation.
Nature 1987;327(6117):67-70.
1987: Michel Bouvier; L M Leeb-Lundberg; J L Benovic; Marc G Caron; R J Lefkowitz
Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase.
The Journal of biological chemistry 1987;262(7):3106-13.
1986: Michel Bouvier; J de Champlain
Effects of acute and chronic administration of sotalol on the blood pressure and the sympathoadrenal activity of anesthetized deoxycorticosterone acetate-salt hypertensive rats.
Canadian journal of physiology and pharmacology 1986;64(9):1164-9.
1986: Michel Bouvier; J de Champlain
Increased sympatho-adrenal tone and adrenal medulla reactivity in DOCA-salt hypertensive rats.
Journal of hypertension 1986;4(2):157-63.
1986: Michel Bouvier; J de Champlain
Increased basal and reactive plasma norepinephrine and epinephrine levels in awake DOCA-salt hypertensive rats.
Journal of the autonomic nervous system 1986;15(2):191-5.
1985: Jacques de Champlain; Michel Bouvier; N Gravel; J Cléroux; G Drolet; S Foucart; H Eid
[Role of the sympathetic nervous system in arterial hypertension].
L'unión médicale du Canada 1985;114(12):977-81, 986.
1985: Michel Bouvier; J de Champlain
Increased apparent norepinephrine release rate in anesthetized DOCA-salt hypertensive rats.
Clinical and experimental hypertension. Part A, Theory and practice 1985;7(11):1629-45.
1984: J de Champlain; Michel Bouvier; J Cléroux; L Farley
Free and conjugated catecholamines in plasma and red blood cells of normotensive and hypertensive patients.
Clinical and experimental hypertension. Part A, Theory and practice 1984;6(1-2):523-37.
1983: Michel Bouvier; J de Champlain
Selective activation of the adrenal medulla during acute bilateral carotid occlusion and its modulation by alpha-adrenergic receptors in the rat.
Canadian journal of physiology and pharmacology 1983;61(4):381-7.