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Hidetoshi Tahara

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Dan Xu; Hidetoshi Tahara
The role of exosomes and microRNAs in senescence and aging.
Saori Fukunaga; Hidetoshi Tahara
[The significance of microRNA in breast cancer cells].
Dan Xu; Fumitaka Takeshita; Yumiko Hino; Saori Fukunaga; Yasusei Kudo; Aya Tamaki; Junko Matsunaga; Ryou-u Takahashi; Takashi Takata; Akira Shimamoto; Takahiro Ochiya; Hidetoshi Tahara
miR-22 represses cancer progression by inducing cellular senescence.

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2013: Dan Xu; Hidetoshi Tahara
The role of exosomes and microRNAs in senescence and aging.
Advanced drug delivery reviews 2013;65(3):368-75.
2012: Saori Fukunaga; Hidetoshi Tahara
[The significance of microRNA in breast cancer cells].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 7():84-7.
2011: Dan Xu; Fumitaka Takeshita; Yumiko Hino; Saori Fukunaga; Yasusei Kudo; Aya Tamaki; Junko Matsunaga; Ryou-u Takahashi; Takashi Takata; Akira Shimamoto; Takahiro Ochiya; Hidetoshi Tahara
miR-22 represses cancer progression by inducing cellular senescence.
The Journal of cell biology 2011;193(2):409-24.
2011: Yoshiyuki Matsumoto; Tatsuo Miyamoto; Hiromi Sakamoto; Hideki Izumi; Yuka Nakazawa; Tomoo Ogi; Hidetoshi Tahara; Shozo Oku; Azuma Hiramoto; Toshihide Shiiki; Yoshiki Fujisawa; Hirofumi Ohashi; Yoshihiro Sakemi; Shinya Matsuura
Two unrelated patients with MRE11A mutations and Nijmegen breakage syndrome-like severe microcephaly.
DNA repair 2011;10(3):314-21.
2011: Hidetoshi Tahara
Telomere G-overhang length measurement method 2: G-tail telomere HPA.
Methods in molecular biology (Clifton, N.J.) 2011;735():55-61.
2010: Koji Waki; Kumiko Anno; Taeko Ono; Toshinori Ide; Kazuaki Chayama; Hidetoshi Tahara
Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development.
Cancer science 2010;101(7):1678-85.
2008: Manabu Hashimoto; Satoru Kyo; Xianxin Hua; Hidetoshi Tahara; Miki Nakajima; Masahiro Takakura; Junko Sakaguchi; Yoshiko Maida; Mitsuhiro Nakamura; Tomomi Ikoma; Yasunari Mizumoto; Masaki Inoue
Role of menin in the regulation of telomerase activity in normal and cancer cells.
International journal of oncology 2008;33(2):333-40.
2008: Yukiko Muramatsu; Hidetoshi Tahara; Taeko Ono; Takashi Tsuruo; Hiroyuki Seimiya
Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation.
Experimental cell research 2008;314(5):1115-24.
2007: Yukari Saka; Osamu Yoshimura; Hidetoshi Tahara; Yayoi Takeda; Hideki Moriyama; Hiroshi Maejima; Yoshiko Tobimatsu
The mRNA expression of neurotrophins in different skeletal muscles of young rats.
Hiroshima journal of medical sciences 2007;56(3-4):23-8.
2007: Masae Kitagawa; Ikuko Ogawa; Kaori Shima; Sadamitsu Hashimoto; Yasusei Kudo; Mutsumi Miyauchi; Hidetoshi Tahara; Masaki Shimono; Takashi Takata
Immortalization and characterization of pleomorphic adenoma cells by transfection with the hTERT gene.
International journal of oncology 2007;31(2):339-44.
2007: Masae Kitagawa; Hirota Ueda; Sinji Iizuka; Kiyako Sakamoto; Hiroko Oka; Yasusei Kudo; Ikuko Ogawa; Mutsumi Miyauchi; Hidetoshi Tahara; Takashi Takata
Immortalization and characterization of human dental pulp cells with odontoblastic differentiation.
Archives of oral biology 2007;52(8):727-31.
2007: Kumiko Anno; Akane Hayashi; Tomoko Takahashi; Youji Mitsui; Toshinori Ide; Hidetoshi Tahara
Telomerase activation induces elongation of the telomeric single-stranded overhang, but does not prevent chromosome aberrations in human vascular endothelial cells.
Biochemical and biophysical research communications 2007;353(4):926-32.
2006: Louis Yuge; Teruyuki Kajiume; Hidetoshi Tahara; Yumi Kawahara; Chika Umeda; Reiko Yoshimoto; Shu-Liang Wu; Kazuko Yamaoka; Makoto Asashima; Katsuko Kataoka; Toshinori Ide
Microgravity potentiates stem cell proliferation while sustaining the capability of differentiation.
Stem cells and development 2006;15(6):921-9.
2006: Hua He; Asha S Multani; Wilfredo Cosme-Blanco; Hidetoshi Tahara; Jin Ma; Sen Pathak; Yibin Deng; Sandy Chang
POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination.
The EMBO journal 2006;25(21):5180-90.
2006: Akiko Takahashi; Naoko Ohtani; Kimi Yamakoshi; Shin-ichi Iida; Hidetoshi Tahara; Keiko Nakayama; Keiichi I Nakayama; Toshinori Ide; Hideyuki Saya; Eiji Hara
Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence.
Nature cell biology 2006;8(11):1291-7.
2006: Masae Kitagawa; Hidetoshi Tahara; Shoji Kitagawa; Hiroko Oka; Yasusei Kudo; Sunao Sato; Ikuko Ogawa; Mutsumi Miyaichi; Takashi Takata
Characterization of established cementoblast-like cell lines from human cementum-lining cells in vitro and in vivo.
Bone 2006;39(5):1035-42.
2006: Ling Wu; Asha S Multani; Hua He; Wilfredo Cosme-Blanco; Yu Deng; Jian Min Deng; Olga Bachilo; Sen Pathak; Hidetoshi Tahara; Susan M Bailey; Yibin Deng; Richard R Behringer; Sandy Chang
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres.
Cell 2006;126(1):49-62.
2006: Hidetoshi Tahara; K Shin-Ya; H Seimiya; H Yamada; Takashi Tsuruo; Toshinori Ide
G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells.
Oncogene 2006;25(13):1955-66.
2006: Hidetoshi Tahara; Toshinori Ide
[Telomere and telomerase in age related diseases].
Seikagaku. The Journal of Japanese Biochemical Society 2006;78(3):230-41.
2006: Shinya Matsuura; Yoshiyuki Matsumoto; Ken-ichi Morishima; Hideki Izumi; Hiroshi Matsumoto; Emi Ito; Keisuke Tsutsui; Junya Kobayashi; Hiroshi Tauchi; Yoshinori Kajiwara; Seiji Hama; Kaoru Kurisu; Hidetoshi Tahara; Mitsuo Oshimura; Kenshi Komatsu; Tatsuro Ikeuchi; Tadashi Kajii
Monoallelic BUB1B mutations and defective mitotic-spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome.
American journal of medical genetics. Part A 2006;140(4):358-67.
2006: Junya Taomoto; Kazuhiro Yoshida; Yoshiyuki Wada; Kazuaki Tanabe; Kazuo Konishi; Hidetoshi Tahara; Masakazu Fukushima
Overexpression of the orotate phosphoribosyl-transferase gene enhances the effect of 5-fluorouracil on gastric cancer cell lines.
Oncology 2006;70(6):458-64.
2005: Tomohisa Fujita; Yoko Otsuka-Tanaka; Hidetoshi Tahara; Toshinori Ide; Yoshimitsu Abiko; Junichi Mega
Establishment of immortalized clonal cells derived from periodontal ligament cells by induction of the hTERT gene.
Journal of oral science 2005;47(4):177-84.
2005: Naohiro Tsuyama; Inaho Danjoh; Ken-ichiro Otsuyama; Masanori Obata; Hidetoshi Tahara; Tsutomu Ohta; Hideaki Ishikawa
IL-6-induced Bcl6 variant 2 supports IL-6-dependent myeloma cell proliferation and survival through STAT3.
Biochemical and biophysical research communications 2005;337(1):201-8.
2005: Hidetoshi Tahara; Mayuko Kusunoki; Yusuke Yamanaka; Shusaku Matsumura; Toshinori Ide
G-tail telomere HPA: simple measurement of human single-stranded telomeric overhangs.
Nature methods 2005;2(11):829-31.
2005: Masae Kitagawa; Shoji Kitagawa; Yasusei Kudo; Ikuko Ogawa; Mutsumi Miyauchi; Hidetoshi Tahara; Toshinori Ide; Takashi Takata
Establishment of cementoblast cell lines from rat cementum lining cells by transfection with temperature-sensitive simian virus-40 T-antigen gene.
Bone 2005;37(2):220-6.
2005: Eiichi Tahara; Hidetoshi Tahara; Masamoto Kanno; Kazuhito Naka; Yayoi Takeda; Takeshi Matsuzaki; Ryuta Yamazaki; Hiroto Ishihara; Wataru Yasui; J Carl Barrett; Toshinori Ide; Eiichi Tahara
G1P3, an interferon inducible gene 6-16, is expressed in gastric cancers and inhibits mitochondrial-mediated apoptosis in gastric cancer cell line TMK-1 cell.
Cancer immunology, immunotherapy : CII 2005;54(8):729-40.
2004: Tohru Higaki; Taro Watanabe; Ichiro Tamatomi; Hidetoshi Tahara; Masanobu Sugimoto; Yasuhiro Furuichi; Toshinori Ide
Terminal telomere repeats are actually short in telomerase-negative immortal human cells.
Biological & pharmaceutical bulletin 2004;27(12):1932-8.
2004: Masanobu Sugimoto; Hidetoshi Tahara; Minoru Okubo; Tetsuro Kobayashi; Makoto Goto; Toshinori Ide; Yasuhiro Furuichi
WRN gene and other genetic factors affecting immortalization of human B-lymphoblastoid cell lines transformed by Epstein-Barr virus.
Cancer genetics and cytogenetics 2004;152(2):95-100.
2004: Masanobu Sugimoto; Hidetoshi Tahara; Toshinori Ide; Yasuhiro Furuichi
Steps involved in immortalization and tumorigenesis in human B-lymphoblastoid cell lines transformed by Epstein-Barr virus.
Cancer research 2004;64(10):3361-4.
2003: Tomoko Takahashi; Tamae Kawabe; Yuichi Okazaki; Chie Itoh; Keisuke Noda; Manami Tajima; Misako Satoh; Makoto Goto; Youji Mitsui; Hidetoshi Tahara; Toshinori Ide; Yasuhiro Furuichi; Masanobu Sugimoto
In vitro establishment of tumorigenic human B-lymphoblastoid cell lines transformed by Epstein-Barr virus.
DNA and cell biology 2003;22(11):727-35.
2002: Takeki Tsutsui; Shin-ichi Kumakura; Akito Yamamoto; Hideaki Kanai; Yukiko Tamura; Takashi Kato; Masanori Anpo; Hidetoshi Tahara; J Carl Barrett
Association of p16(INK4a) and pRb inactivation with immortalization of human cells.
Carcinogenesis 2002;23(12):2111-7.
2002: Yasuo Yano; Kazuhiro Yoshida; Akihiko Osaki; Tetsuya Toge; Hidetoshi Tahara; Toshinori Ide; Wataru Yasui
Expression and distribution of human telomerase catalytic component, hTERT, in human breast tissues.
Anticancer research 2002;22(6C):4101-7.
2002: Sara A Carney; Hidetoshi Tahara; Carol D Swartz; John Risinger; Hong He; Alicia B Moore; Joseph K Haseman; J Carl Barrett; Darlene Dixon
Immortalization of human uterine leiomyoma and myometrial cell lines after induction of telomerase activity: molecular and phenotypic characteristics.
Laboratory investigation; a journal of technical methods and pathology 2002;82(6):719-28.
2001: Norimasa Matsutani; Hiroshi Yokozaki; Eiichi Tahara; Hidetoshi Tahara; Hiroki Kuniyasu; Ken Haruma; Kazuaki Chayama; Wataru Yasui; E Tahara
Expression of telomeric repeat binding factor 1 and 2 and TRF1-interacting nuclear protein 2 in human gastric carcinomas.
International journal of oncology 2001;19(3):507-12.
2001: T Minamoto; T Buschmann; H Habelhah; E Matusevich; Hidetoshi Tahara; A L Boerresen-Dale; C Harris; David Sidransky; Ze'ev Ronai
Distinct pattern of p53 phosphorylation in human tumors.
Oncogene 2001;20(26):3341-7.
2001: Norimasa Matsutani; Hiroshi Yokozaki; E Tahara; Hidetoshi Tahara; Hiroki Kuniyasu; Yasuhiko Kitadai; Ken Haruma; Kazuaki Chayama; Eiichi Tahara; Wataru Yasui
Expression of MRE11 complex (MRE11, RAD50, NBS1) and hRap1 and its relation with telomere regulation, telomerase activity in human gastric carcinomas.
Pathobiology : journal of immunopathology, molecular and cellular biology 2001;69(4):219-24.
2000: S O Mueller; Hidetoshi Tahara; J C Barrett; K S Korach
Immortalization of mammary cells from estrogen receptor alpha knock-out and wild-type mice.
In vitro cellular & developmental biology. Animal 2000;36(10):620-4.
2000: K Harada; K Kurisu; Hidetoshi Tahara; E Tahara; T Ide; E Tahara
Telomerase activity in primary and secondary glioblastomas multiforme as a novel molecular tumor marker.
Journal of neurosurgery 2000;93(4):618-25.
2000: Y Kawakami; Mikiya Kitamoto; T Nakanishi; Wataru Yasui; E Tahara; J Nakayama; F Ishikawa; Hidetoshi Tahara; Toshinori Ide; G Kajiyama
Immuno-histochemical detection of human telomerase reverse transcriptase in human liver tissues.
Oncogene 2000;19(34):3888-93.
2000: K Harada; Kaoru Kurisu; T Sadatomo; Hidetoshi Tahara; Eiichi Tahara; Toshinori Ide; E Tahara
Growth inhibition of human glioma cells by transfection-induced P21 and its effects on telomerase activity.
Journal of neuro-oncology 2000;47(1):39-46.
2000: K Harada; Kazunori Arita; Kaoru Kurisu; Hidetoshi Tahara
Telomerase activity and the expression of telomerase components in pituitary adenoma with malignant transformation.
Surgical neurology 2000;53(3):267-74.
2000: Shoichi Takahashi; Mikiya Kitamoto; H Takaishi; Hiroshi Aikata; Y Kawakami; Toshio Nakanishi; Fumio Shimamoto; E Tahara; Hidetoshi Tahara; Toshinori Ide; Goro Kajiyama
Expression of telomerase component genes in hepatocellular carcinomas.
European journal of cancer (Oxford, England : 1990) 2000;36(4):496-502.
2000: J Fujimoto; Wataru Yasui; Hidetoshi Tahara; Eiichi Tahara; Yasusei Kudo; Hiroshi Yokozaki; E Tahara
DNA hypermethylation at the pS2 promoter region is associated with early stage of stomach carcinogenesis.
Cancer letters 2000;149(1-2):125-34.
2000: Hiroshi Yokozaki; Hidetoshi Tahara; Naohide Oue; Eiichi Tahara
Cloning of a human hepatocyte growth factor/scatter factor transcription variant from a gastric cancer cell line HSC-39.
International journal of oncology 2000;16(1):105-8.
1999: Y Nakamura; E Tahara; Hidetoshi Tahara; W Yasui; T Ide
Quantitative reevaluation of telomerase activity in cancerous and noncancerous gastrointestinal tissues.
Molecular carcinogenesis 1999;26(4):312-20.
1999: Y Ishii; Naohiro Tsuyama; S Maeda; Hidetoshi Tahara; Toshinori Ide
Telomerase activity in hybrids between telomerase-negative and telomerase-positive immortal human cells is repressed in the different complementation groups but not in the same complementation group of immortality.
Mechanisms of ageing and development 1999;110(3):175-93.
1999: K Harada; Kaoru Kurisu; Kazunori Arita; T Sadatomo; Hidetoshi Tahara; Eiichi Tahara; Toshinori Ide; T Uozumi
Telomerase activity in central nervous system malignant lymphoma.
Cancer 1999;86(6):1050-5.
1999: Wataru Yasui; Hiroshi Yokozaki; F Shimamoto; Hidetoshi Tahara; Eiichi Tahara
Molecular-pathological diagnosis of gastrointestinal tissues and its contribution to cancer histopathology.
Pathology international 1999;49(9):763-74.
1999: Wataru Yasui; Eiichi Tahara; Hidetoshi Tahara; J Fujimoto; K Naka; J Nakayama; F Ishikawa; T Ide; E Tahara
Immunohistochemical detection of human telomerase reverse transcriptase in normal mucosa and precancerous lesions of the stomach.
Japanese journal of cancer research : Gann 1999;90(6):589-95.
1999: Hidetoshi Tahara; Wataru Yasui; E Tahara; J Fujimoto; K Ito; Katsuyuki Tamai; J Nakayama; F Ishikawa; E Tahara; Toshinori Ide
Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections.
Oncogene 1999;18(8):1561-7.
1999: K Naka; Hiroshi Yokozaki; Wataru Yasui; Hidetoshi Tahara; Eiichi Tahara; E Tahara
Effect of antisense human telomerase RNA transfection on the growth of human gastric cancer cell lines.
Biochemical and biophysical research communications 1999;255(3):753-8.
1998: M Hirose; J Abe-Hashimoto; Hidetoshi Tahara; T Ide; T Yoshimura
New method to measure telomerase activity by transcription-mediated amplification and hybridization protection assay.
Clinical chemistry 1998;44(12):2446-52.
1998: T Hiyama; Hiroshi Yokozaki; Yasuhiko Kitadai; Eiichi Tahara; Hidetoshi Tahara; T Ide; K Haruma; Wataru Yasui; G Kajiyama; E Tahara
In situ mRNA hybridization technique for analysis of human telomerase RNA in gastric precancerous and cancerous lesions.
Japanese journal of cancer research : Gann 1998;89(11):1187-94.
1998: Wataru Yasui; Hidetoshi Tahara; Eiichi Tahara; J Fujimoto; J Nakayama; F Ishikawa; T Ide; E Tahara
Expression of telomerase catalytic component, telomerase reverse transcriptase, in human gastric carcinomas.
Japanese journal of cancer research : Gann 1998;89(11):1099-103.
1998: Kenjiro Aogi; K Kitahara; Ian D Buley; M Backdahl; Hidetoshi Tahara; Takashi Sugino; David Tarin; Steve Goodison
Telomerase activity in lesions of the thyroid: application to diagnosis of clinical samples including fine-needle aspirates.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(8):1965-70.
1998: Y Tokutake; Takehisa Matsumoto; T Watanabe; S Maeda; Hidetoshi Tahara; S Sakamoto; Hiroyuki Niida; M Sugimoto; T Ide; Yasuhiro Furuichi
Extra-chromosomal telomere repeat DNA in telomerase-negative immortalized cell lines.
Biochemical and biophysical research communications 1998;247(3):765-72.
1998: H C Li; Hidetoshi Tahara; Naohiro Tsuyama; Toshinori Ide
A hVti1 homologue: its expression depends on population doubling levels in both normal and SV40-transformed human fibroblasts.
Biochemical and biophysical research communications 1998;247(1):70-4.
1998: Toru Hiyama; Hiroshi Yokozaki; Yasuhiko Kitadai; Hidetoshi Tahara; Wataru Yasui; Eiichi Tahara
[Analysis of expression of human telomerase RNA in gastric precancerous and cancerous lesions by using in situ mRNA hybridization].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(5):1190-3.
1998: K Naka; Hiroshi Yokozaki; Hidetoshi Tahara; Eiichi Tahara
[Application of antisense human telomerase RNA toward cancer therapy].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(5):1131-5.
1998: J Nakayama; Hidetoshi Tahara; E Tahara; M Saito; K Ito; H Nakamura; T Nakanishi; E Tahara; T Ide; Fuyuki Ishikawa
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas.
Nature genetics 1998;18(1):65-8.
1997: H Kataoka; Hidetoshi Tahara; T Watanabe; M Sugawara; T Ide; M Goto; Yasuhiro Furuichi; M Sugimoto
Immortalization of immunologically committed Epstein-Barr virus-transformed human B-lymphoblastoid cell lines accompanied by a strong telomerase activity.
Differentiation; research in biological diversity 1997;62(4):203-11.
1997: Hidetoshi Tahara; Eiichi Tahara; E Tahara; T Ide
[Telomere and telomerase associated genes].
Gan to kagaku ryoho. Cancer & chemotherapy 1997;24(15):2196-201.
1997: Hidetoshi Tahara; Y Tokutake; S Maeda; H Kataoka; T Watanabe; M Satoh; T Matsumoto; M Sugawara; Toshinori Ide; M Goto; Y Furuichi; M Sugimoto
Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus.
Oncogene 1997;15(16):1911-20.
1997: J Murakami; N Nagai; K Ohama; Hidetoshi Tahara; Toshinori Ide
Telomerase activity in ovarian tumors.
Cancer 1997;80(6):1085-92.
1997: K Nakabayashi; T Ogata; Michihiko Fujii; Hidetoshi Tahara; T Ide; R Wadhwa; S C Kaul; Y Mitsui; Dai Ayusawa
Decrease in amplified telomeric sequences and induction of senescence markers by introduction of human chromosome 7 or its segments in SUSM-1.
Experimental cell research 1997;235(2):345-53.
1997: Toshinori Ide; Hidetoshi Tahara
[Human senescence, cancer and telomerase].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(9):1351-74.
1997: S Kannan; Hidetoshi Tahara; H Yokozaki; Babu Mathew; K R Nalinakumari; M Krishnan Nair; E Tahara
Telomerase activity in premalignant and malignant lesions of human oral mucosa.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(6):413-20.
1997: R Nakashio; Mikiya Kitamoto; Hidetoshi Tahara; Toshio Nakanishi; T Ide; Goro Kajiyama
Significance of telomerase activity in the diagnosis of small differentiated hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 1997;74(2):141-7.
1997: Hiroki Kuniyasu; T Domen; T Hamamoto; Hiroshi Yokozaki; Wataru Yasui; Hidetoshi Tahara; Eiichi Tahara
Expression of human telomerase RNA is an early event of stomach carcinogenesis.
Japanese journal of cancer research : Gann 1997;88(2):103-7.
1997: K Yoshida; Takashi Sugino; Hidetoshi Tahara; Anthony C Woodman; J Bolodeoku; V Nargund; G Fellows; Steve Goodison; E Tahara; David Tarin
Telomerase activity in bladder carcinoma and its implication for noninvasive diagnosis by detection of exfoliated cancer cells in urine.
Cancer 1997;79(2):362-9.
1997: M Hirose; J Abe-Hashimoto; K Ogura; Hidetoshi Tahara; T Ide; T Yoshimura
A rapid, useful and quantitative method to measure telomerase activity by hybridization protection assay connected with a telomeric repeat amplification protocol.
Journal of cancer research and clinical oncology 1997;123(6):337-44.
1996: Toshinori Ide; Hidetoshi Tahara; R Nakashio; Mikiya Kitamoto; Toshio Nakanishi; Goro Kajiyama
Telomerase in hepatocellular carcinogenesis.
Human cell 1996;9(4):283-6.
1996: Takashi Sugino; K Yoshida; J Bolodeoku; Hidetoshi Tahara; Ian D Buley; S Manek; C Wells; Steve Goodison; T Ide; T Suzuki; E Tahara; David Tarin
Telomerase activity in human breast cancer and benign breast lesions: diagnostic applications in clinical specimens, including fine needle aspirates.
International journal of cancer. Journal international du cancer 1996;69(4):301-6.
1996: Yoshihiko Akama; Wataru Yasui; Hiroki Kuniyasu; Hiroshi Yokozaki; M Akagi; Hidetoshi Tahara; T Ishikawa; Eiichi Tahara
Genetic status and expression of the cyclin-dependent kinase inhibitors in human gastric carcinoma cell lines.
Japanese journal of cancer research : Gann 1996;87(8):824-30.
1996: S Yasumoto; C Kunimura; K Kikuchi; Hidetoshi Tahara; H Ohji; H Yamamoto; T Ide; T Utakoji
Telomerase activity in normal human epithelial cells.
Oncogene 1996;13(2):433-9.
1996: Eiichi Tahara; S Semba; Hidetoshi Tahara
Molecular biological observations in gastric cancer.
Seminars in oncology 1996;23(3):307-15.
1996: Nobutaka Nagai; J Murakami; Hidetoshi Tahara
[Telomerase activity of uterine cancer examined by telomeric repeat amplification protocol assay].
Nihon Sanka Fujinka Gakkai zasshi 1996;48(4):277-8.
1996: M Akagi; Wataru Yasui; Yoshihiko Akama; Hiroshi Yokozaki; Hidetoshi Tahara; Ken Haruma; Goro Kajiyama; Eiichi Tahara
Inhibition of cell growth by transforming growth factor beta 1 is associated with p53-independent induction of p21 in gastric carcinoma cells.
Japanese journal of cancer research : Gann 1996;87(4):377-84.
1996: Eiji Hara; R Smith; D Parry; Hidetoshi Tahara; S Stone; Gordon Peters
Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence.
Molecular and cellular biology 1996;16(3):859-67.
1996: T Ide; Hidetoshi Tahara
[Telomerase].
Gan to kagaku ryoho. Cancer & chemotherapy 1996;23(3):247-56.
1995: Hidetoshi Tahara; Hiroki Kuniyasu; H Yokozaki; W Yasui; Jerry W Shay; T Ide; E Tahara
Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(11):1245-51.
1995: H Ohmura; Hidetoshi Tahara; M Suzuki; T Ide; M Shimizu; M A Yoshida; E Tahara; J W Shay; J Carl Barrett; Mitsuo Oshimura
Restoration of the cellular senescence program and repression of telomerase by human chromosome 3.
Japanese journal of cancer research : Gann 1995;86(10):899-904.
1995: Hidetoshi Tahara; K Kamada; E Sato; Naohiro Tsuyama; J K Kim; E Hara; K Oda; Toshinori Ide
Increase in expression levels of interferon-inducible genes in senescent human diploid fibroblasts and in SV40-transformed human fibroblasts with extended lifespan.
Oncogene 1995;11(6):1125-32.
1995: M Fujii; Toshinori Ide; R Wadhwa; Hidetoshi Tahara; Sunil C Kaul; Y Mitsui; T Ogata; M Oishi; D Ayusawa
Inhibitors of cGMP-dependent protein kinase block senescence induced by inactivation of T antigen in SV40-transformed immortal human fibroblasts.
Oncogene 1995;11(4):627-34.
1995: Hidetoshi Tahara; Toshio Nakanishi; Mikiya Kitamoto; R Nakashio; Jerry W Shay; Eiichi Tahara; Goro Kajiyama; Toshinori Ide
Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas.
Cancer research 1995;55(13):2734-6.
1995: Yoshihiko Akama; Wataru Yasui; Hiroki Kuniyasu; Hiroshi Yokozaki; Hidetoshi Tahara; A Noda; Eiichi Tahara
[Expression of sdi1, a potent inhibitor of cdk2 kinase, cdk2 and G1 cyclins and mutation of sdi1 in human gastric carcinomas].
Gan to kagaku ryoho. Cancer & chemotherapy 1995;22 Suppl 2():180.
1995: Hidetoshi Tahara; E Sato; A Noda; Toshinori Ide
Increase in expression level of p21sdi1/cip1/waf1 with increasing division age in both normal and SV40-transformed human fibroblasts.
Oncogene 1995;10(5):835-40.
1994: Hidetoshi Tahara; E Hara; Naohiro Tsuyama; K Oda; Toshinori Ide
Preparation of a subtractive cDNA library enriched in cDNAs which expressed at a high level in cultured senescent human fibroblasts.
Biochemical and biophysical research communications 1994;199(3):1108-12.
1993: E Hara; T Yamaguchi; Hidetoshi Tahara; Naohiro Tsuyama; H Tsurui; T Ide; K Oda
DNA-DNA subtractive cDNA cloning using oligo(dT)30-Latex and PCR: identification of cellular genes which are overexpressed in senescent human diploid fibroblasts.
Analytical biochemistry 1993;214(1):58-64.