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Mauro Carai

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Barbara Loi; Paolo Morazzoni; Antonella Riva; Ezio Bombardelli; Giancarlo Colombo; Noemi Fantini; Gian Luigi Gessa; Mauro A M Carai
Reducing effect of an extract of Phaseolus vulgaris on food intake in mice--focus on highly palatable foods.
Barbara Loi; Paola Maccioni; Pari Malherbe; Andrew W Thomas; Mauro A M Carai; Gian Luigi Gessa; Carla Lobina; Giancarlo Colombo
Reduction of alcohol intake by the positive allosteric modulator of the GABA(B) receptor, rac-BHFF, in alcohol-preferring rats.
Barbara Loi; Paolo Morazzoni; Antonella Riva; Ezio Bombardelli; Giancarlo Colombo; Noemi Fantini; Gian Luigi Gessa; Mauro A M Carai
Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on food intake and glycemia in rats.

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All Publications

2013: Barbara Loi; Paolo Morazzoni; Antonella Riva; Ezio Bombardelli; Giancarlo Colombo; Noemi Fantini; Gian Luigi Gessa; Mauro A M Carai
Reducing effect of an extract of Phaseolus vulgaris on food intake in mice--focus on highly palatable foods.
Fitoterapia 2013;85():14-9.
2013: Barbara Loi; Paola Maccioni; Pari Malherbe; Andrew W Thomas; Mauro A M Carai; Gian Luigi Gessa; Carla Lobina; Giancarlo Colombo
Reduction of alcohol intake by the positive allosteric modulator of the GABA(B) receptor, rac-BHFF, in alcohol-preferring rats.
Alcohol (Fayetteville, N.Y.) 2013;47(1):69-73.
2013: Barbara Loi; Paolo Morazzoni; Antonella Riva; Ezio Bombardelli; Giancarlo Colombo; Noemi Fantini; Gian Luigi Gessa; Mauro A M Carai
Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on food intake and glycemia in rats.
Phytotherapy research : PTR 2013;27(2):258-63.
2013: Yan Zhou; Jorge Manzanares; Keiichi Niikura; Mauro A M Carai; Giancarlo Colombo; Teresa Femenía; Maria S García-Gutiérrez; Gian Luigi Gessa; Ann Ho; Mary Jeanne Kreek
Voluntary alcohol drinking enhances proopiomelanocortin gene expression in nucleus accumbens shell and hypothalamus of Sardinian alcohol-preferring rats.
Alcoholism, clinical and experimental research 2013;37 Suppl 1():E131-40.
2012: Paola Maccioni; Claudia Mugnaini; Serena Pasquini; Alessandro Zaru; Federico Corelli; Gian Luigi Gessa; Petri Hyytiä; Carla Lobina; Barbara Loi; Lawrence Lumeng; Alessandro Capra; Mauro A M Carai; Giancarlo Colombo
Comparison of the effect of the GABA(B) receptor agonist, baclofen, and the positive allosteric modulator of the GABA(B) receptor, GS39783, on alcohol self-administration in 3 different lines of alcohol-preferring rats.
Alcoholism, clinical and experimental research 2012;36(10):1748-66.
2012: Roberta Agabio; Mauro A M Carai; Wolfgang Froestl; Gian Luigi Gessa; Paola Maccioni; Giancarlo Colombo
The development of medications for alcohol-use disorders targeting the GABAB receptor system.
Recent patents on CNS drug discovery 2012;7(2):113-28.
2012: M Paola Castelli; Paola Casti; Angelo Casu; Giancarlo Colombo; Gian Luigi Gessa; Daniela Giunta; Carla Lobina; Claudia Mugnaini; Serena Pasquini; Maurizio Solinas; Andrea Tafi; Simone Brogi; Mauro A M Carai; Federico Corelli
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA(B) receptor.
The Journal of pharmacology and experimental therapeutics 2012;340(3):529-38.
2012: Giancarlo Colombo; Mauro A M Carai; Gian Luigi Gessa
Suppression by γ-Hydroxybutyric Acid of "Alcohol Deprivation Effect" in Rats: Preclinical Evidence of its anti-Relapse Properties.
Frontiers in psychiatry / Frontiers Research Foundation 2012;3():95.
2012: Antonella Loche; Francesco Simonetti; Domenico Barone; Mauro A M Carai; M Paola Castelli; Giancarlo Colombo; Carla Lobina; Roberto Cacciaglia
Anti-Alcohol and Anxiolytic Properties of a New Chemical Entity, GET73.
Frontiers in psychiatry / Frontiers Research Foundation 2012;3():8.
2011: Yan Zhou; Mauro A M Carai; Giancarlo Colombo; Gian Luigi Gessa; Ann Ho; Mary Jeanne Kreek
Involvement of arginine vasopressin and V1b receptor in alcohol drinking in Sardinian alcohol-preferring rats.
Alcoholism, clinical and experimental research 2011;35(10):1876-83.
2011: Mauro A M Carai; Giancarlo Colombo; Noemi Fantini; Gian Luigi Gessa; Barbara Loi; Ezio Bombardelli; Antonella Riva; Paolo Morazzoni
Multiple cycles of repeated treatments with a Phaseolus vulgaris dry extract reduce food intake and body weight in obese rats.
The British journal of nutrition 2011;106(5):762-8.
2011: Noemi Fantini; Giancarlo Colombo; Andrea Giori; Antonella Riva; Paolo Morazzoni; Ezio Bombardelli; Mauro A M Carai
Evidence of glycemia-lowering effect by a Cynara scolymus L. extract in normal and obese rats.
Phytotherapy research : PTR 2011;25(3):463-6.
2010: Barbara Loi; Carla Lobina; Paola Maccioni; Noemi Fantini; Mauro A M Carai; Gian Luigi Gessa; Giancarlo Colombo
Increase in alcohol intake, reduced flexibility of alcohol drinking, and evidence of signs of alcohol intoxication in Sardinian alcohol-preferring rats exposed to intermittent access to 20% alcohol.
Alcoholism, clinical and experimental research 2010;34(12):2147-54.
2010: Paola Maccioni; Giancarlo Colombo; Antonella Riva; Paolo Morazzoni; Ezio Bombardelli; Gian Luigi Gessa; Mauro A M Carai
Reducing effect of a Phaseolus vulgaris dry extract on operant self-administration of a chocolate-flavoured beverage in rats.
The British journal of nutrition 2010;104(5):624-8.
2010: Paola Maccioni; Andrew W Thomas; Mauro A M Carai; Gian Luigi Gessa; Pari Malherbe; Giancarlo Colombo
The positive allosteric modulator of the GABA(B) receptor, rac-BHFF, suppresses alcohol self-administration.
Drug and alcohol dependence 2010;109(1-3):96-103.
2010: Paola Maccioni; Giancarlo Colombo; Mauro A M Carai
Blockade of the cannabinoid CB1 receptor and alcohol dependence: preclinical evidence and preliminary clinical data.
CNS & neurological disorders drug targets 2010;9(1):55-9.
2010: Paola Maccioni; Paolo Flore; Mauro A M Carai; Claudia Mugnaini; Serena Pasquini; Federico Corelli; Gian Luigi Gessa; Giancarlo Colombo
Reduction by the Positive Allosteric Modulator of the GABA(B) Receptor, GS39783, of Alcohol Self-Administration in Sardinian Alcohol-Preferring Rats Exposed to the "Sipper" Procedure.
Frontiers in psychiatry / Frontiers Research Foundation 2010;1():20.
2009: Noemi Fantini; Claudia Cabras; Carla Lobina; Giancarlo Colombo; Gian Luigi Gessa; Antonella Riva; Fabio Donzelli; Paolo Morazzoni; Ezio Bombardelli; Mauro A M Carai
Reducing effect of a Phaseolus vulgaris dry extract on food intake, body weight, and glycemia in rats.
Journal of agricultural and food chemistry 2009;57(19):9316-23.
2009: Paola Maccioni; Mauro A M Carai; Klemens Kaupmann; Sébastien Guery; Wolfgang Froestl; Kimberly A Leite-Morris; Gian Luigi Gessa; Giancarlo Colombo
Reduction of alcohol's reinforcing and motivational properties by the positive allosteric modulator of the GABA(B) receptor, BHF177, in alcohol-preferring rats.
Alcoholism, clinical and experimental research 2009;33(10):1749-56.
2009: Mauro A M Carai; Noemi Fantini; Barbara Loi; Giancarlo Colombo; Antonella Riva; Paolo Morazzoni
Potential efficacy of preparations derived from Phaseolus vulgaris in the control of appetite, energy intake, and carbohydrate metabolism.
Diabetes, metabolic syndrome and obesity : targets and therapy 2009;2():145-53.
2009: Marina Rubio; Rosario De Miguel; Javier Fernández-Ruiz; Dolores Gutiérrez-López; Mauro A M Carai; José A Ramos
Effects of a short-term exposure to alcohol in rats on FAAH enzyme and CB1 receptor in different brain areas.
Drug and alcohol dependence 2009;99(1-3):354-8.
2008: Paola Maccioni; Noemi Fantini; Wolfgang Froestl; Mauro A M Carai; Gian Luigi Gessa; Giancarlo Colombo
Specific reduction of alcohol's motivational properties by the positive allosteric modulator of the GABAB receptor, GS39783--comparison with the effect of the GABAB receptor direct agonist, baclofen.
Alcoholism, clinical and experimental research 2008;32(9):1558-64.
2008: Paola Maccioni; Przemyslaw Bienkowski; Mauro A M Carai; Gian Luigi Gessa; Giancarlo Colombo
Baclofen attenuates cue-induced reinstatement of alcohol-seeking behavior in Sardinian alcohol-preferring (sP) rats.
Drug and alcohol dependence 2008;95(3):284-7.
2008: Paola Maccioni; Daniela Pes; Mauro A M Carai; Gian Luigi Gessa; Giancarlo Colombo
Suppression by the cannabinoid CB1 receptor antagonist, rimonabant, of the reinforcing and motivational properties of a chocolate-flavoured beverage in rats.
Behavioural pharmacology 2008;19(3):197-209.
2008: Paola Maccioni; Daniela Pes; Noemi Fantini; Mauro A M Carai; Gian Luigi Gessa; Giancarlo Colombo
gamma-Hydroxybutyric acid (GHB) suppresses alcohol's motivational properties in alcohol-preferring rats.
Alcohol (Fayetteville, N.Y.) 2008;42(2):107-13.
2008: Mauro A M Carai; Carla Lobina; Paola Maccioni; Claudia Cabras; Giancarlo Colombo; Gian Luigi Gessa
Gamma-aminobutyric acidB (GABAB)-receptor mediation of different in vivo effects of gamma-butyrolactone.
Journal of pharmacological sciences 2008;106(2):199-207.
2007: Alessandro Orrù; Carla Lobina; Paola Maccioni; Gian Luigi Gessa; Mauro A M Carai; Giancarlo Colombo
Repeated exposure to alcoholic beer does not induce long-lasting changes in alcohol self-administration and intake in Sardinian alcohol-preferring and Sardinian non-preferring rats.
Alcohol and alcoholism (Oxford, Oxfordshire) 2007;42(6):513-24.
2007: Giancarlo Colombo; Alessandro Orrù; Paola Lai; Claudia Cabras; Paola Maccioni; Marina Rubio; Gian Luigi Gessa; Mauro A M Carai
The cannabinoid CB1 receptor antagonist, rimonabant, as a promising pharmacotherapy for alcohol dependence: preclinical evidence.
Molecular neurobiology 2007;36(1):102-12.
2007: Paola Maccioni; Daniela Pes; Alessandro Orrù; Wolfgang Froestl; Gian Luigi Gessa; Mauro A M Carai; Giancarlo Colombo
Reducing effect of the positive allosteric modulator of the GABA(B) receptor, GS39,783, on alcohol self-administration in alcohol-preferring rats.
Psychopharmacology 2007;193(2):171-8.
2007: Paola Maccioni; Alessandro Orrú; Agnieszka Korkosz; Gian Luigi Gessa; Mauro A M Carai; Giancarlo Colombo; Przemyslaw Bienkowski
Cue-induced reinstatement of ethanol seeking in Sardinian alcohol-preferring rats.
Alcohol (Fayetteville, N.Y.) 2007;41(1):31-9.
2006: Giancarlo Colombo; Salvatore Serra; Giovanni Vacca; Mauro A M Carai; Gian Luigi Gessa
Baclofen-induced suppression of alcohol deprivation effect in Sardinian alcohol-preferring (sP) rats exposed to different alcohol concentrations.
European journal of pharmacology 2006;550(1-3):123-6.
2006: Giancarlo Colombo; Carla Lobina; Mauro A M Carai; Gian Luigi Gessa
Phenotypic characterization of genetically selected Sardinian alcohol-preferring (sP) and -non-preferring (sNP) rats.
Addiction biology 2006;11(3-4):324-38.
2006: Lawrence S Quang; Giancarlo Colombo; Carla Lobina; Paola Maccioni; Alessandro Orru; Gian Luigi Gessa; Timothy J Maher; Mauro A M Carai
Evaluation for the withdrawal syndrome from gamma-hydroxybutyric acid (GHB), gamma-butyrolactone (GBL), and 1,4-butanediol (1,4-BD) in different rat lines.
Annals of the New York Academy of Sciences 2006;1074():545-58.
2006: Mauro A M Carai; Giancarlo Colombo; Gian Luigi Gessa; Ratnakumar Yalamanchili; Balapal S Basavarajappa; Balapal S Basavarajppa; Basalingappa L Hungund
Investigation on the relationship between cannabinoid CB1 and opioid receptors in gastrointestinal motility in mice.
British journal of pharmacology 2006;148(8):1043-50.
2006: Giancarlo Colombo; Salvatore Serra; Giovanni Vacca; Alessandro Orrù; Paola Maccioni; Paolo Morazzoni; Ezio Bombardelli; Antonella Riva; Gian Luigi Gessa; Mauro A M Carai
Identification of miltirone as active ingredient of Salvia miltiorrhiza responsible for the reducing effect of root extracts on alcohol intake in rats.
Alcoholism, clinical and experimental research 2006;30(5):754-62.
2006: Gian Luigi Gessa; Alessandro Orrù; Paola Lai; Paola Maccioni; Rossella Lecca; Carla Lobina; Mauro A M Carai; Giancarlo Colombo
Lack of tolerance to the suppressing effect of rimonabant on chocolate intake in rats.
Psychopharmacology 2006;185(2):248-54.
2006: Mauro A M Carai; Giancarlo Colombo; Lawrence S Quang; Timothy J Maher; Gian Luigi Gessa
Resuscitative treatments on 1,4-butanediol mortality in mice.
Annals of emergency medicine 2006;47(2):184-9.
2006: Mauro A M Carai; Giancarlo Colombo; Paola Maccioni; Gian Luigi Gessa
Efficacy of rimonabant and other cannabinoid CB1 receptor antagonists in reducing food intake and body weight: preclinical and clinical data.
CNS drug reviews 2006;12(2):91-9.
2005: Alessandro Orrù; Paola Lai; Carla Lobina; Paola Maccioni; Patrizia Piras; Laura Scanu; Wolfgang Froestl; Gian Luigi Gessa; Mauro A M Carai; Giancarlo Colombo
Reducing effect of the positive allosteric modulators of the GABA(B) receptor, CGP7930 and GS39783, on alcohol intake in alcohol-preferring rats.
European journal of pharmacology 2005;525(1-3):105-11.
2005: M Paola Castelli; Fabio Pibiri; A Paola Piras; Giovanni Carboni; Alessandro Orrù; Gian Luigi Gessa; Mauro A M Carai; Giancarlo Colombo
Differential G-protein coupling to GABAB receptor in limbic areas of alcohol-preferring and -nonpreferring rats.
European journal of pharmacology 2005;523(1-3):67-70.
2005: Mauro A M Carai; Giancarlo Colombo; Gian Luigi Gessa
Rimonabant: the first therapeutically relevant cannabinoid antagonist.
Life sciences 2005;77(19):2339-50.
2005: Paola Maccioni; Salvatore Serra; Giovanni Vacca; Alessandro Orrù; Daniela Pes; Roberta Agabio; Giovanni Addolorato; Mauro A M Carai; Gian Luigi Gessa; Giancarlo Colombo
Baclofen-induced reduction of alcohol reinforcement in alcohol-preferring rats.
Alcohol (Fayetteville, N.Y.) 2005;36(3):161-8.
2005: Maria Luisa Barbaccia; Mauro A M Carai; Giancarlo Colombo; Carla Lobina; Robert H Purdy; Gian Luigi Gessa
Endogenous gamma-aminobutyric acid (GABA)(A) receptor active neurosteroids and the sedative/hypnotic action of gamma-hydroxybutyric acid (GHB): a study in GHB-S (sensitive) and GHB-R (resistant) rat lines.
Neuropharmacology 2005;49(1):48-58.
2005: Mauro A M Carai; Lawrence S Quang; Sergio Atzeri; Carla Lobina; Paola Maccioni; Alessandro Orrù; Gian Luigi Gessa; Timothy J Maher; Giancarlo Colombo
Withdrawal syndrome from gamma-hydroxybutyric acid (GHB) and 1,4-butanediol (1,4-BD) in Sardinian alcohol-preferring rats.
Brain research. Brain research protocols 2005;15(2):75-8.
2005: Mauro A M Carai; Giancarlo Colombo; Gian Luigi Gessa
Resuscitative effect of a gamma-aminobutyric acid B receptor antagonist on gamma-hydroxybutyric acid mortality in mice.
Annals of emergency medicine 2005;45(6):614-9.
2005: Giancarlo Colombo; Salvatore Serra; Giovanni Vacca; Mauro A M Carai; Gian Luigi Gessa
Endocannabinoid system and alcohol addiction: pharmacological studies.
Pharmacology, biochemistry, and behavior 2005;81(2):369-80.
2005: Fabio Pibiri; Giovanni Carboni; Mauro A M Carai; Gian Luigi Gessa; M Paola Castelli
Up-regulation of GABA(B) receptors by chronic administration of the GABA(B) receptor antagonist SCH 50,911.
European journal of pharmacology 2005;515(1-3):94-8.
2005: Gabriele Murineddu; Stefania Ruiu; Jean-Mario Mussinu; Giovanni Loriga; Giuseppe E Grella; Mauro A M Carai; Paolo Lazzari; Luca Pani; Gérard A Pinna
Tricyclic pyrazoles. Part 2: Synthesis and biological evaluation of novel 4,5-dihydro-1H-benzo[g]indazole-based ligands for cannabinoid receptors.
Bioorganic & medicinal chemistry 2005;13(9):3309-20.
2005: Carla Lobina; Giancarlo Colombo; Alessandro Orrù; Paola Maccioni; Gian Luigi Gessa; Mauro A M Carai
GHB-C rats: the control line of GHB-sensitive (GHB-S) and GHB-resistant (GHB-R) rats.
Brain research. Brain research protocols 2005;15(1):1-5.
2005: Carla Lobina; Giancarlo Colombo; Gian Luigi Gessa; Mauro A M Carai
Different sensitivity to the motor incoordinating effects of gamma-hydroxybutyric acid (GHB) and baclofen in GHB-sensitive and GHB-resistant rats.
Brain research 2005;1033(1):109-12.
2005: Giancarlo Colombo; Salvatore Serra; Giovanni Vacca; Mauro A M Carai; Gian Luigi Gessa
Effect of the combination of naltrexone and baclofen, on acquisition of alcohol drinking behavior in alcohol-preferring rats.
Drug and alcohol dependence 2005;77(1):87-91.
2005: Giancarlo Colombo; Carla Lobina; Paola Maccioni; M Francesca Mascia; Alessandro Orrù; Gian Luigi Gessa; Mauro A M Carai
Suppression of maintenance of alcohol-drinking behavior by the concurrent availability of saccharin in Sardinian alcohol-preferring (sP) rats.
Alcohol (Fayetteville, N.Y.) 2005;35(1):35-41.
2005: Giancarlo Colombo; Carla Lobina; Paola Maccioni; M Francesca Mascia; Alessandro Orrù; Gian Luigi Gessa; Mauro A M Carai
Suppression of acquisition of alcohol-drinking behavior by the concurrent availability of saccharin in Sardinian alcohol-preferring (sP) rats.
Alcohol (Fayetteville, N.Y.) 2005;35(1):27-33.
2005: Gian Luigi Gessa; Salvatore Serra; Giovanni Vacca; Mauro A M Carai; Giancarlo Colombo
Suppressing effect of the cannabinoid CB1 receptor antagonist, SR147778, on alcohol intake and motivational properties of alcohol in alcohol-preferring sP rats.
Alcohol and alcoholism (Oxford, Oxfordshire) 2005;40(1):46-53.
2004: Mauro A M Carai; Giancarlo Colombo; Wolfgang Froestl; Gian Luigi Gessa
In vivo effectiveness of CGP7930, a positive allosteric modulator of the GABAB receptor.
European journal of pharmacology 2004;504(3):213-6.
2004: Mauro A M Carai; Giancarlo Colombo; Gian Luigi Gessa
Protection by the GABAB receptor antagonist, SCH 50911, of gamma-hydroxybutyric acid-induced mortality in mice.
European journal of pharmacology 2004;503(1-3):77-80.
2004: Giancarlo Colombo; Giovanni Vacca; Salvatore Serra; Mauro A M Carai; Gian Luigi Gessa
Suppressing effect of the cannabinoid CB1 receptor antagonist, SR 141716, on alcohol's motivational properties in alcohol-preferring rats.
European journal of pharmacology 2004;498(1-3):119-23.
2004: Mauro A M Carai; Giovanni Vacca; Salvatore Serra; Giancarlo Colombo; Wolfgang Froestl; Gian Luigi Gessa
Suppression of GABA(B) receptor function in vivo by disulfide reducing agent, DL-dithiothreitol (DTT).
Psychopharmacology 2004;174(2):283-90.
2004: Mauro A M Carai; Giancarlo Colombo; Gian Luigi Gessa
Rapid tolerance to the intestinal prokinetic effect of cannabinoid CB1 receptor antagonist, SR 141716 (Rimonabant).
European journal of pharmacology 2004;494(2-3):221-4.
2004: Giancarlo Colombo; Salvatore Serra; Giovanni Vacca; Gian Luigi Gessa; Mauro A M Carai
Suppression by baclofen of the stimulation of alcohol intake induced by morphine and WIN 55,212-2 in alcohol-preferring rats.
European journal of pharmacology 2004;492(2-3):189-93.
2004: Carla Lobina; Giancarlo Colombo; Gian Luigi Gessa; Mauro A M Carai
Completion by the 10th generation of the bidirectional selective breeding of GHB-sensitive and GHB-resistant rats.
Brain research. Brain research protocols 2004;13(1):53-6.
2004: Giancarlo Colombo; Giovanni Addolorato; Roberta Agabio; Mauro A M Carai; Fabio Pibiri; Salvatore Serra; Giovanni Vacca; Gian Luigi Gessa
Role of GABA(B) receptor in alcohol dependence: reducing effect of baclofen on alcohol intake and alcohol motivational properties in rats and amelioration of alcohol withdrawal syndrome and alcohol craving in human alcoholics.
Neurotoxicity research 2004;6(5):403-14.
2003: M Paola Castelli; Luca Ferraro; Ignazia Mocci; Francesca Carta; Mauro A M Carai; Tiziana Antonelli; Sergio Tanganelli; Giorgio Cignarella; Gian Luigi Gessa
Selective gamma-hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of gamma-hydroxybutyric acid.
Journal of neurochemistry 2003;87(3):722-32.
2003: Salvatore Serra; Giovanni Vacca; Silvia Tumatis; Angela Carrucciu; Paolo Morazzoni; Ezio Bombardelli; Giancarlo Colombo; Gian Luigi Gessa; Mauro A M Carai
Anti-relapse properties of IDN 5082, a standardized extract of Salvia miltiorrhiza, in alcohol-preferring rats.
Journal of ethnopharmacology 2003;88(2-3):249-52.
2003: Giuliana Brunetti; Salvatore Serra; Giovanni Vacca; Carla Lobina; Tiziana Curreli; Mauro A M Carai; Giancarlo Colombo; Gian Luigi Gessa
Long-term exposure to a sweetened alcoholic solution does not alter genetic aversion to ethanol in Sardinian alcohol-nonpreferring (sNP) rats.
Alcohol (Fayetteville, N.Y.) 2003;30(1):29-34.
2003: Giovanni Vacca; Giancarlo Colombo; Giuliana Brunetti; Samuele Melis; Daniela Molinari; Salvatore Serra; Roberto Seghizzi; Paolo Morazzoni; Ezio Bombardelli; Gian Luigi Gessa; Mauro A M Carai
Reducing effect of Salvia miltiorrhiza extracts on alcohol intake: influence of vehicle.
Phytotherapy research : PTR 2003;17(5):537-41.
2003: Giancarlo Colombo; Salvatore Serra; Giuliana Brunetti; Giovanni Vacca; Mauro A M Carai; Gian Luigi Gessa
Suppression by baclofen of alcohol deprivation effect in Sardinian alcohol-preferring (sP) rats.
Drug and alcohol dependence 2003;70(1):105-8.
2003: Giancarlo Colombo; Giovanni Vacca; Salvatore Serra; Giuliana Brunetti; Mauro A M Carai; Gian Luigi Gessa
Baclofen suppresses motivation to consume alcohol in rats.
Psychopharmacology 2003;167(3):221-4.
2003: Luciano Tedeschi; Mauro A M Carai; Giampietro Frison; Donata Favretto; Giancarlo Colombo; Santo Davide Ferrara; Gian Luigi Gessa
Endogenous gamma-hydroxybutyric acid is in the rat, mouse and human gastrointestinal tract.
Life sciences 2003;72(22):2481-8.
2003: Giuliana Brunetti; Salvatore Serra; Giovanni Vacca; Carla Lobina; Paolo Morazzoni; Ezio Bombardelli; Giancarlo Colombo; Gian Luigi Gessa; Mauro A M Carai
IDN 5082, a standardized extract of Salvia miltiorrhiza, delays acquisition of alcohol drinking behavior in rats.
Journal of ethnopharmacology 2003;85(1):93-7.
2003: Salvatore Serra; Giuliana Brunetti; Giovanni Vacca; Carla Lobina; Mauro A M Carai; Gian Luigi Gessa; Giancarlo Colombo
Stable preference for high ethanol concentrations after ethanol deprivation in Sardinian alcohol-preferring (sP) rats.
Alcohol (Fayetteville, N.Y.) 2003;29(2):101-8.
2003: Jean-Mario Mussinu; Stefania Ruiu; Antonio C Mulè; Amedeo Pau; Mauro A M Carai; Giovanni Loriga; Gabriele Murineddu; Gérard A Pinna
Tricyclic pyrazoles. Part 1: synthesis and biological evaluation of novel 1,4-dihydroindeno[1,2-c]pyrazol-based ligands for CB1and CB2 cannabinoid receptors.
Bioorganic & medicinal chemistry 2003;11(2):251-63.
2003: Maria Antonietta Casu; Anna Porcella; Stefania Ruiu; Pierluigi Saba; Giorgio Marchese; Mauro A M Carai; Roberta Reali; Gian Luigi Gessa; Luca Pani
Differential distribution of functional cannabinoid CB1 receptors in the mouse gastroenteric tract.
European journal of pharmacology 2003;459(1):97-105.
2002: Giovanni Vacca; Salvatore Serra; Giuliana Brunetti; Mauro A M Carai; Herman H Samson; Gian Luigi Gessa; Giancarlo Colombo
Operant self-administration of ethanol in Sardinian alcohol-preferring rats.
Alcoholism, clinical and experimental research 2002;26(11):1678-85.
2002: Giancarlo Colombo; Salvatore Serra; Giuliana Brunetti; Giuliana Atzori; Marialaura Pani; Giovanni Vacca; Giovanni Addolorato; Wolfgang Froestl; Mauro A M Carai; Gian Luigi Gessa
The GABA(B) receptor agonists baclofen and CGP 44532 prevent acquisition of alcohol drinking behaviour in alcohol-preferring rats.
Alcohol and alcoholism (Oxford, Oxfordshire) 2002;37(5):499-503.
2002: Mauro A M Carai; Giuliana Brunetti; Carla Lobina; Salvatore Serra; Giovanni Vacca; Giovanna Minardi; Giancarlo Colombo; Gian Luigi Gessa
Proconvulsive effect of the GABA(B) receptor antagonist, SCH 50911, in rats undergoing ethanol withdrawal syndrome.
European journal of pharmacology 2002;445(3):195-9.
2002: Giovanni Vacca; Salvatore Serra; Giuliana Brunetti; Mauro A M Carai; Gian Luigi Gessa; Giancarlo Colombo
Boosting effect of morphine on alcohol drinking is suppressed not only by naloxone but also by the cannabinoid CB1 receptor antagonist, SR 141716.
European journal of pharmacology 2002;445(1-2):55-9.
2002: Salvatore Serra; Giuliana Brunetti; Marialaura Pani; Giovanni Vacca; Mauro A M Carai; Gian Luigi Gessa; Giancarlo Colombo
Blockade by the cannabinoid CB(1) receptor antagonist, SR 141716, of alcohol deprivation effect in alcohol-preferring rats.
European journal of pharmacology 2002;443(1-3):95-7.
2002: Mauro A M Carai; Roberta Agabio; Carla Lobina; Roberta Reali; Giovanni Vacca; Giancarlo Colombo; Gian Luigi Gessa
GABA(B)-receptor mediation of the inhibitory effect of gamma-hydroxybutyric acid on intestinal motility in mice.
Life sciences 2002;70(25):3059-67.
2002: Maria Luisa Barbaccia; Giancarlo Colombo; D Affricano; Mauro A M Carai; Giovanni Vacca; Samuele Melis; Robert H Purdy; Gian Luigi Gessa
GABA(B) receptor-mediated increase of neurosteroids by gamma-hydroxybutyric acid.
Neuropharmacology 2002;42(6):782-91.
2002: Mauro A M Carai; Giancarlo Colombo; Roberta Reali; Salvatore Serra; Ignazia Mocci; M Paola Castelli; Giorgio Cignarella; Gian Luigi Gessa
Central effects of 1,4-butanediol are mediated by GABA(B) receptors via its conversion into gamma-hydroxybutyric acid.
European journal of pharmacology 2002;441(3):157-63.
2002: Giuliana Brunetti; Mauro A M Carai; Carla Lobina; Samuele Melis; Salvatore Serra; Giovanni Vacca; Gian Luigi Gessa; Giancarlo Colombo
Differences in ethanol-induced conditioned taste aversion in Sardinian alcohol-preferring and Sardinian alcohol-nonpreferring rats.
Alcohol (Fayetteville, N.Y.) 2002;26(3):167-72.
2002: Salvatore Serra; Giancarlo Colombo; Samuele Melis; Giovanni Vacca; Mauro A M Carai; Gian Luigi Gessa
Gamma-hydroxybutyric acid versus alcohol preference in Sardinian alcohol-preferring rats.
Alcohol and alcoholism (Oxford, Oxfordshire) 2002;37(2):128-31.
2001: Giancarlo Colombo; Samuele Melis; Giuliana Brunetti; Salvatore Serra; Giovanni Vacca; Mauro A M Carai; Gian Luigi Gessa
GABA(B) receptor inhibition causes locomotor stimulation in mice.
European journal of pharmacology 2001;433(1):101-4.
2001: Salvatore Serra; Mauro A M Carai; Giuliana Brunetti; R Gomez; Samuele Melis; Giovanni Vacca; Giancarlo Colombo; Gian Luigi Gessa
The cannabinoid receptor antagonist SR 141716 prevents acquisition of drinking behavior in alcohol-preferring rats.
European journal of pharmacology 2001;430(2-3):369-71.
2001: Mauro A M Carai; Giancarlo Colombo; Giuliana Brunetti; Samuele Melis; Salvatore Serra; Giovanni Vacca; S Mastinu; A M Pistuddi; C Solinas; Giorgio Cignarella; G Minardi; Gian Luigi Gessa
Role of GABA(B) receptors in the sedative/hypnotic effect of gamma-hydroxybutyric acid.
European journal of pharmacology 2001;428(3):315-21.
2001: Carla Lobina; Giancarlo Colombo; Giuliana Brunetti; Giacomo Diaz; Samuele Melis; Marialaura Pani; Salvatore Serra; Giovanni Vacca; Gian Luigi Gessa; Mauro A M Carai
Procedure of bidirectional selective outbreeding for production of two rat lines differing in sensitivity to the sedative/hypnotic effect of gamma-hydroxybutyric acid.
Brain research. Brain research protocols 2001;8(1):74-81.
2001: Giancarlo Colombo; Carla Lobina; Roberta Agabio; Giuliana Brunetti; Giacomo Diaz; M Littera; Samuele Melis; Marialaura Pani; Roberta Reali; Salvatore Serra; Giovanni Vacca; Mauro A M Carai; Gian Luigi Gessa
Selective breeding of two rat lines differing in sensitivity to GHB and baclofen.
Brain research 2001;902(1):127-30.
2001: Roberta Agabio; Mauro A M Carai; Carla Lobina; Marialaura Pani; Roberta Reali; Giovanni Vacca; Gian Luigi Gessa; Giancarlo Colombo
Alcohol stimulates motor activity in selectively bred Sardinian alcohol-preferring (sP), but not in Sardinian alcohol-nonpreferring (sNP), rats.
Alcohol (Fayetteville, N.Y.) 2001;23(2):123-6.
2000: Giancarlo Colombo; Roberta Agabio; Mauro A M Carai; Carla Lobina; Marialaura Pani; Roberta Reali; Giovanni Vacca; Gian Luigi Gessa
Different sensitivity to ethanol in alcohol-preferring sP and -nonpreferring sNP rats.
Alcoholism, clinical and experimental research 2000;24(11):1603-8.
2000: Mauro A M Carai; Roberta Agabio; Ezio Bombardelli; I Bourov; Gian Luigi Gessa; Carla Lobina; Paolo Morazzoni; Marialaura Pani; Roberta Reali; Giovanni Vacca; Giancarlo Colombo
Potential use of medicinal plants in the treatment of alcoholism.
Fitoterapia 2000;71 Suppl 1():S38-42.
2000: Roberta Agabio; Mauro A M Carai; Carla Lobina; Marialaura Pani; Roberta Reali; Giovanni Vacca; Gian Luigi Gessa; Giancarlo Colombo
Development of short-lasting alcohol deprivation effect in sardinian alcohol-preferring rats.
Alcohol (Fayetteville, N.Y.) 2000;21(1):59-62.
2000: Gian Luigi Gessa; Roberta Agabio; Mauro A M Carai; Carla Lobina; Marialaura Pani; Roberta Reali; Giancarlo Colombo
Mechanism of the antialcohol effect of gamma-hydroxybutyric acid.
Alcohol (Fayetteville, N.Y.) 2000;20(3):271-6.
2000: Giancarlo Colombo; Roberta Agabio; Mauro A M Carai; Carla Lobina; Marialaura Pani; Roberta Reali; Gian Luigi Gessa
Characterization of the discriminative stimulus effects of gamma-hydroxybutyric acid as a means for unraveling the neurochemical basis of gamma-hydroxybutyric acid actions and its similarities to those of ethanol.
Alcohol (Fayetteville, N.Y.) 2000;20(3):237-45.
2000: Giancarlo Colombo; Roberta Agabio; Mauro A M Carai; Carla Lobina; Marialaura Pani; Roberta Reali; Giovanni Addolorato; Gian Luigi Gessa
Ability of baclofen in reducing alcohol intake and withdrawal severity: I--Preclinical evidence.
Alcoholism, clinical and experimental research 2000;24(1):58-66.
2000: Roberta Agabio; Mauro A M Carai; Carla Lobina; Marialaura Pani; Roberta Reali; I Bourov; Gian Luigi Gessa; Giancarlo Colombo
Dissociation of ethanol and saccharin preference in sP and sNP rats.
Alcoholism, clinical and experimental research 2000;24(1):24-9.