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Rork Kuick

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Lesley A Rakowski; Sarah Caruso; Tomasz Cierpicki; Margaret Decker; Derek D Garagiola; Morgan Jones; Rork Kuick; Choi M Li; Ivan P Maillard; Mark Chiang
Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias.
Joanne H Heaton; Alex C Kim; Rork Kuick; Ana C Latronico; Antonio M Lerario; Lorena O Lima; Derek P Simon; Ibere C Soares; Elisabeth Starnes; Dafydd Thomas; Michelle A Wood; Madson Q Almeida; Ferdous M Barlaskar; Maria C B V Fragoso; Thomas J Giordano; Gary Hammer
Progression to adrenocortical tumorigenesis in mice and humans through insulin-like growth factor 2 and β-catenin.
Shan He; Koji Kato; Rork Kuick; Yongnian Liu; Ram-Shankar Mani; Victor E Marquez; Shin Mineishi; Kazuhiro Mochizuki; Evelyn Nieves; Sooryanarayana Lnu; J Wang; Fang Xie; Arul M Chinnaiyan; Yi Zhang
Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells.

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All Publications

2013: Lesley A Rakowski; Sarah Caruso; Tomasz Cierpicki; Margaret Decker; Derek D Garagiola; Morgan Jones; Rork Kuick; Choi M Li; Ivan P Maillard; Mark Chiang
Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias.
Cancer research 2013;73(2):930-41.
2012: Joanne H Heaton; Alex C Kim; Rork Kuick; Ana C Latronico; Antonio M Lerario; Lorena O Lima; Derek P Simon; Ibere C Soares; Elisabeth Starnes; Dafydd Thomas; Michelle A Wood; Madson Q Almeida; Ferdous M Barlaskar; Maria C B V Fragoso; Thomas J Giordano; Gary Hammer
Progression to adrenocortical tumorigenesis in mice and humans through insulin-like growth factor 2 and β-catenin.
The American journal of pathology 2012;181(3):1017-33.
2012: Shan He; Koji Kato; Rork Kuick; Yongnian Liu; Ram-Shankar Mani; Victor E Marquez; Shin Mineishi; Kazuhiro Mochizuki; Evelyn Nieves; Sooryanarayana Lnu; J Wang; Fang Xie; Arul M Chinnaiyan; Yi Zhang
Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells.
Blood 2012;119(5):1274-82.
2011: Ajaya Kumar Reka; Theodore J Standiford; Rork Kuick; Himabindu Kurapati; Gilbert S Omenn; Venkateshwar Keshamouni
Identifying inhibitors of epithelial-mesenchymal transition by connectivity map-based systems approach.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011;6(11):1784-92.
2011: Theodore J Standiford; Rork Kuick; Urvashi Bhan; Jun Chen; Michael W Newstead; Venkateshwar Keshamouni
TGF-β-induced IRAK-M expression in tumor-associated macrophages regulates lung tumor growth.
Oncogene 2011;30(21):2475-84.
2011: Chitra Subramanian; Jason A Jarzembowski; Sonja M Halsey; Rork Kuick; Anthony William Opipari Jr; Valerie P Castle; Roland P S Kwok
CLU blocks HDACI-mediated killing of neuroblastoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2011;32(2):285-94.
2010: Victoria R Kelly; Bin Xu; Rork Kuick; Ronald J Koenig; Gary Hammer
Dax1 up-regulates Oct4 expression in mouse embryonic stem cells via LRH-1 and SRA.
Molecular endocrinology (Baltimore, Md.) 2010;24(12):2281-91.
2010: Koji Kato; Shuaiying Cui; Rork Kuick; Shin Mineishi; Elizabeth Hexner; James L M Ferrara; Stephen G Emerson; Yi Zhang
Identification of stem cell transcriptional programs normally expressed in embryonic and neural stem cells in alloreactive CD8+ T cells mediating graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(6):751-71.
2010: Maureen Sartor; Vasudeva Mahavisno; Venkateshwar Keshamouni; James Cavalcoli; Zachary Wright; Alla Karnovsky; Rork Kuick; HV Jagadish; Barbara Mirel; Terry Weymouth; Brian D Athey; Gilbert S Omenn
ConceptGen: a gene set enrichment and gene set relation mapping tool.
Bioinformatics (Oxford, England) 2010;26(4):456-63.
2010: Bommer Guido; Ying Feng; Ayaka Iura; Thomas J Giordano; Rork Kuick; Hüseyin Kadikoy; Deanna Sikorski; Rong Wu; Kathleen R Cho; Guido Bommer
IRS1 regulation by Wnt/beta-catenin signaling and varied contribution of IRS1 to the neoplastic phenotype.
The Journal of biological chemistry 2010;285(3):1928-38.
2009: Aghiad Chamdin; Jason A Jarzembowski; Chitra Subramanian; Rork Kuick; Julia Shin-Jung Lee; Roland P S Kwok; Valerie P Castle; Anthony William Opipari Jr
Bcl6 is expressed in neuroblastoma: tumor cell type-specific expression predicts outcome.
Translational oncology 2009;2(3):128-37.
2009: Tobias Else; Alessia Trovato; Alex C Kim; Yipin Wu; David O Ferguson; Rork Kuick; Peter C Lucas; Gary Hammer
Genetic p53 deficiency partially rescues the adrenocortical dysplasia phenotype at the expense of increased tumorigenesis.
Cancer cell 2009;15(6):465-76.
2009: A Kim; Thomas J Giordano; Rork Kuick; K Serecky; Gary Hammer
Wnt/betacatenin signaling in adrenocortical stem/progenitor cells: implications for adrenocortical carcinoma.
Annales d'endocrinologie 2009;70(3):156.
2009: Eduardo Vilar; Bhramar Mukherjee; Rork Kuick; Leonid Raskin; David E Misek; Jeremy Taylor; Thomas J Giordano; Samir M Hanash; Eric R Fearon; Gad Rennert; Stephen B Gruber
Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(8):2829-39.
2009: Ying Liu; Rork Kuick; Samir Hanash; Bruce C Richardson
DNA methylation inhibition increases T cell KIR expression through effects on both promoter methylation and transcription factors.
Clinical immunology (Orlando, Fla.) 2009;130(2):213-24.
2009: Thomas J Giordano; Rork Kuick; Tobias Else; Paul G Gauger; Michelle Vinco; Juliane Bauersfeld; Donita Sanders; Dafydd Thomas; Gerard M Doherty; Gary Hammer
Molecular classification and prognostication of adrenocortical tumors by transcriptome profiling.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(2):668-76.
2009: Sophie Paczesny; Oleg I Krijanovski; Thomas M Braun; Sung Won Choi; Shawn G Clouthier; Rork Kuick; David E Misek; Kenneth R Cooke; Carrie L Kitko; Angela Weyand; Daniel Bickley; Dawn Jones; Joel Whitfield; Pavan Reddy; John E Levine; Samir M Hanash; James L M Ferrara
A biomarker panel for acute graft-versus-host disease.
Blood 2009;113(2):273-8.
2009: Venkateshwar Keshamouni; Pratik Jagtap; George Michailidis; John R Strahler; Rork Kuick; Ajaya Kumar Reka; Panagiotis Papoulias; Rashmi Krishnapuram; Anjaiah Srirangam; Theodore J Standiford; Philip C Andrews; Gilbert S Omenn
Temporal quantitative proteomics by iTRAQ 2D-LC-MS/MS and corresponding mRNA expression analysis identify post-transcriptional modulation of actin-cytoskeleton regulators during TGF-beta-Induced epithelial-mesenchymal transition.
Journal of proteome research 2009;8(1):35-47.
2009: Ferdous M Barlaskar; Aaron C Spalding; Joanne H Heaton; Rork Kuick; Alex C Kim; Dafydd Thomas; Thomas J Giordano; Edgar Ben-Josef; Gary Hammer
Preclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma.
The Journal of clinical endocrinology and metabolism 2009;94(1):204-12.
2008: Navneet Sangha; Rong Wu; Rork Kuick; Scott Powers; David Mu; Diane Fiander; Kit Yuen; Hidetaka Katabuchi; Hironori Tashiro; Eric R Fearon; Kathleen R Cho
Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.
Neoplasia (New York, N.Y.) 2008;10(12):1362-72, following 1372.
2008: Melanie Ehrlich; Cecilia Sanchez; Chunbo Shao; Rie Nishiyama; John Kehrl; Rork Kuick; Takeo Kubota; Samir M Hanash
ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation.
Autoimmunity 2008;41(4):253-71.
2008: Juan Madoz-Gúrpide; Rork Kuick; Hong Wang; David E Misek; Samir M Hanash
Integral protein microarrays for the identification of lung cancer antigens in sera that induce a humoral immune response.
Molecular & cellular proteomics : MCP 2008;7(2):268-81.
2007: Sandra R Pereira-Faca; Rork Kuick; Eric Puravs; Qing Zhang; Alexei L Krasnoselsky; Douglas Phanstiel; Ji Qiu; David E Misek; Robert Hinderer; Martin Tammemagi; Maria Teresa Landi; Neil Caporaso; Ruth Pfeiffer; Cim Edelstein; Gary Goodman; Matt Barnett; Mark D Thornquist; Dean E Brenner; Samir M Hanash
Identification of 14-3-3 theta as an antigen that induces a humoral response in lung cancer.
Cancer research 2007;67(24):12000-6.
2007: Yali Zhai; Rork Kuick; Bin Nan; Ichiro Ota; Stephen J Weiss; Cornelia L Trimble; Eric R Fearon; Kathleen R Cho
Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion.
Cancer research 2007;67(21):10163-72.
2007: Su He Wang; Mary Van Antwerp; Rork Kuick; Paul G Gauger; Gerard M Doherty; Yang-Yi Fan; James R Baker Jr
Microarray analysis of cytokine activation of apoptosis pathways in the thyroid.
Endocrinology 2007;148(10):4844-52.
2007: Sara Forrester; Kenneth E Hung; Rork Kuick; Raju Kucherlapati; Brian B Haab
Low-volume, high-throughput sandwich immunoassays for profiling plasma proteins in mice: identification of early-stage systemic inflammation in a mouse model of intestinal cancer.
Molecular oncology 2007;1(2):216-25.
2007: Bommer Guido; Isabelle Gerin; Ying Feng; Andrew J Kaczorowski; Rork Kuick; Robert E Love; Yali Zhai; Thomas J Giordano; Zhaohui S Qin; Bethany B Moore; Ormond A MacDougald; Kathleen R Cho; Guido Bommer
p53-mediated activation of miRNA34 candidate tumor-suppressor genes.
Current biology : CB 2007;17(15):1298-307.
2007: Rork Kuick; David E Misek; David J Monsma; Craig Webb; Hong Wang; Kelli J Peterson; Michael Pisano; Gilbert S Omenn; Samir M Hanash
Discovery of cancer biomarkers through the use of mouse models.
Cancer letters 2007;249(1):40-8.
2007: Rong Wu; Neali Hendrix-Lucas; Rork Kuick; Yali Zhai; Donald R Schwartz; Aytekin Akyol; Samir Hanash; David E Misek; Hidetaka Katabuchi; Bart Williams; Eric R Fearon; Kathleen R Cho
Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.
Cancer cell 2007;11(4):321-33.
2006: Ugljesa Djuric; Osman El-Maarri; Barbara Lamb; Rork Kuick; Muhieddine Seoud; Philippe Coullin; Johannes Oldenburg; Samir Hanash; Rima Slim
Familial molar tissues due to mutations in the inflammatory gene, NALP7, have normal postzygotic DNA methylation.
Human genetics 2006;120(3):390-5.
2006: Constanze H Kubisch; Ilya Gukovsky; Aurelia Lugea; Stephen J Pandol; Rork Kuick; David E Misek; Samir M Hanash; Craig D Logsdon
Long-term ethanol consumption alters pancreatic gene expression in rats: a possible connection to pancreatic injury.
Pancreas 2006;33(1):68-76.
2006: Thomas J Giordano; Amy Y M Au; Rork Kuick; Dafydd Thomas; Daniel R Rhodes; Kenneth G Wilhelm; Michelle Vinco; David E Misek; Donita Sanders; Zhaowen Zhu; Raffaele Ciampi; Samir Hanash; Arul M Chinnaiyan; Roderick J Clifton-Bligh; Bruce G Robinson; Yuri E Nikiforov; Ronald J Koenig
Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(7 Pt 1):1983-93.
2006: Sharlene Murdoch; Ugljesa Djuric; Batool Mazhar; Muhieddine Seoud; Rabia Khan; Rork Kuick; Rashmi Bagga; Renate Kircheisen; Asangla Ao; Bhawna Ratti; Samir Hanash; Guy Rouleau; Rima Slim
Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans.
Nature genetics 2006;38(3):300-2.
2006: Neali D Hendrix; Rong Wu; Rork Kuick; Donald R Schwartz; Eric R Fearon; Kathleen R Cho
Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas.
Cancer research 2006;66(3):1354-62.
2005: Thomas J Giordano; Rork Kuick; Dafydd Thomas; David E Misek; Michelle Vinco; Donita Sanders; Zhaowen Zhu; Raffaele Ciampi; Michael H Roh; Kerby Shedden; Paul G Gauger; Gerard M Doherty; Norman W Thompson; Samir Hanash; Ronald J Koenig; Yuri E Nikiforov
Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis.
Oncogene 2005;24(44):6646-56.
2005: Jocelyn E Wiggins; Meera Goyal; Silja K Sanden; Bryan L Wharram; Kerby Shedden; David E Misek; Rork Kuick; Roger C Wiggins
Podocyte hypertrophy, "adaptation," and "decompensation" associated with glomerular enlargement and glomerulosclerosis in the aging rat: prevention by calorie restriction.
Journal of the American Society of Nephrology : JASN 2005;16(10):2953-66.
2005: David E Misek; Rork Kuick; Hong Wang; Vladimir Galchev; Bin Deng; Rong Zhao; John Tra; Michael R Pisano; Ravi Amunugama; David Allen; Angela Walker; John R Strahler; Philip C Andrews; Gilbert S Omenn; Samir M Hanash
A wide range of protein isoforms in serum and plasma uncovered by a quantitative intact protein analysis system.
Proteomics 2005;5(13):3343-52.
2005: Laura S Rozek; Steven M Lipkin; Eric R Fearon; Samir Hanash; Thomas J Giordano; Joel K Greenson; Rork Kuick; David E Misek; Jeremy Taylor; Julie A Douglas; Gad Rennert; Stephen B Gruber
CDX2 polymorphisms, RNA expression, and risk of colorectal cancer.
Cancer research 2005;65(13):5488-92.
2005: Ji-yao Li; Rork Kuick; Robert C Thompson; David E Misek; Yu-Mei Lai; Y-Q Liu; Biaoxin Chai; Samir M Hanash; Ira Gantz
Arcuate nucleus transcriptome profiling identifies ankyrin repeat and suppressor of cytokine signalling box-containing protein 4 as a gene regulated by fasting in central nervous system feeding circuits.
Journal of neuroendocrinology 2005;17(6):394-404.
2005: Takao Hinoi; Galina Gesina; Aytekin Akyol; Rork Kuick; Samir Hanash; Thomas J Giordano; Stephen B Gruber; Eric R Fearon
CDX2-regulated expression of iron transport protein hephaestin in intestinal and colonic epithelium.
Gastroenterology 2005;128(4):946-61.
2005: Thomas M Williams; Melissa E Williams; Rork Kuick; David E Misek; Kevin T McDonagh; Samir Hanash; Jeffrey W Innis
Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability.
Developmental biology 2005;279(2):462-80.
2005: Myeong J Nam; Mee K Kee; Rork Kuick; Samir M Hanash
Identification of defensin alpha6 as a potential biomarker in colon adenocarcinoma.
The Journal of biological chemistry 2005;280(9):8260-5.
2005: Chad J Creighton; Jennifer L Bromberg-White; David E Misek; David J Monsma; Franck Brichory; Rork Kuick; Thomas J Giordano; Weimin Gao; Gilbert S Omenn; Craig Webb; Samir M Hanash
Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation.
Molecular cancer research : MCR 2005;3(3):119-29.
2005: Wei-Min Gao; Rork Kuick; Randal P Orchekowski; David E Misek; Ji Qiu; Alissa K Greenberg; William N Rom; Dean E Brenner; Gilbert S Omenn; Brian B Haab; Samir M Hanash
Distinctive serum protein profiles involving abundant proteins in lung cancer patients based upon antibody microarray analysis.
BMC cancer 2005;5():110.
2005: Kerby Shedden; Wei Chen; Rork Kuick; Debashis Ghosh; James Macdonald; Kathleen R Cho; Thomas J Giordano; Stephen B Gruber; Eric R Fearon; Jeremy Taylor; Samir Hanash
Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data.
BMC bioinformatics 2005;6():26.
2005: David E Misek; Rork Kuick; Samir M Hanash; Craig D Logsdon
Oligonucleotide-directed microarray gene profiling of pancreatic adenocarcinoma.
Methods in molecular medicine 2005;103():175-87.
2004: Benjamin Marcus; Douglas Arenberg; Julia Lee; Celina G Kleer; Douglas B Chepeha; Cecelia E Schmalbach; Mozaffarul Islam; Supriti Paul; Quintin Pan; Samir Hanash; Rork Kuick; Sofia D Merajver; Theodoros N Teknos
Prognostic factors in oral cavity and oropharyngeal squamous cell carcinoma.
Cancer 2004;101(12):2779-87.
2004: Charles E Binkley; Lizhi Zhang; Joel K Greenson; Thomas J Giordano; Rork Kuick; David E Misek; Samir Hanash; Craig D Logsdon; Diane M Simeone
The molecular basis of pancreatic fibrosis: common stromal gene expression in chronic pancreatitis and pancreatic adenocarcinoma.
Pancreas 2004;29(4):254-63.
2004: Jun-ichi Asakawa; Rork Kuick; Mieko Kodaira; Nori Nakamura; Hiroaki Katayama; Donald Pierce; Sachiyo Funamoto; Dale Preston; Chiyoko Satoh; James V Neel; Samir Hanash
A genome scanning approach to assess the genetic effects of radiation in mice and humans.
Radiation research 2004;161(4):380-90.
2004: Andrea Zatkova; Reinhard Ullmann; Jean-Marie Rouillard; Barbara J Lamb; Rork Kuick; Samir M Hanash; Susanne Schnittger; Claudia Schoch; Christa Fonatsch; Katharina Wimmer
Distinct sequences on 11q13.5 and 11q23-24 are frequently coamplified with MLL in complexly organized 11q amplicons in AML/MDS patients.
Genes, chromosomes & cancer 2004;39(4):263-76.
2004: Ji Qiu; Juan Madoz-Gurpide; David E Misek; Rork Kuick; Dean E Brenner; George Michailidis; Brian B Haab; Gilbert S Omenn; Samir Hanash
Development of natural protein microarrays for diagnosing cancer based on an antibody response to tumor antigens.
Journal of proteome research 2004;3(2):261-7.
2004: Cecelia E Schmalbach; Douglas B Chepeha; Thomas J Giordano; Mark A Rubin; Theodoros N Teknos; Carol R Bradford; Gregory T Wolf; Rork Kuick; David E Misek; Douglas K Trask; Samir Hanash
Molecular profiling and the identification of genes associated with metastatic oral cavity/pharynx squamous cell carcinoma.
Archives of otolaryngology--head & neck surgery 2004;130(3):295-302.
2004: Andrea Zatkova; Jean-Marie Rouillard; Wolfgang Hartmann; Barbara J Lamb; Rork Kuick; Markus Eckart; Dietrich von Schweinitz; Arend Koch; Christa Fonatsch; Torsten Pietsch; Samir M Hanash; Katharina Wimmer
Amplification and overexpression of the IGF2 regulator PLAG1 in hepatoblastoma.
Genes, chromosomes & cancer 2004;39(2):126-37.
2003: Guoan Chen; Tarek G Gharib; Hong Wang; Chiang-Ching Huang; Rork Kuick; Dafydd Thomas; Kerby Shedden; David E Misek; Jeremy Taylor; Thomas J Giordano; Sharon L R Kardia; Mark D Iannettoni; John Yee; Philip J Hogg; Mark B Orringer; Samir M Hanash; David G Beer
Protein profiles associated with survival in lung adenocarcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13537-42.
2003: Myeong J Nam; Juan Madoz-Gurpide; Hong Wang; Pascal A Lescure; Cecelia E Schmalbach; Rong Zhao; David E Misek; Rork Kuick; Dean E Brenner; Samir M Hanash
Molecular profiling of the immune response in colon cancer using protein microarrays: occurrence of autoantibodies to ubiquitin C-terminal hydrolase L3.
Proteomics 2003;3(11):2108-15.
2003: Kerby Shedden; Jeremy Taylor; Thomas J Giordano; Rork Kuick; David E Misek; Gad Rennert; Donald R Schwartz; Stephen B Gruber; Craig D Logsdon; Diane M Simeone; Sharon L R Kardia; Joel K Greenson; Kathleen R Cho; David G Beer; Eric R Fearon; Samir Hanash
Accurate molecular classification of human cancers based on gene expression using a simple classifier with a pathological tree-based framework.
The American journal of pathology 2003;163(5):1985-95.
2003: Annabelle Julius; David E Misek; Rork Kuick; Samir Hanash; James J Mulé
Inducible expression of macrophage receptor Marco by dendritic cells following phagocytic uptake of dead cells uncovered by oligonucleotide arrays.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):2879-88.
2003: Jörg van den Boom; Marietta Wolter; Rork Kuick; David E Misek; Andrew S Youkilis; Daniel Steven Wechsler; Clemens Sommer; Guido Reifenberger; Samir M Hanash
Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction.
The American journal of pathology 2003;163(3):1033-43.
2003: Tamotsu Ichiba; Takanori Teshima; Rork Kuick; David E Misek; Chen Liu; Yuichiro Takada; Yoshinobu Maeda; Pavan Reddy; Debra L Williams; Samir M Hanash; James L M Ferrara
Early changes in gene expression profiles of hepatic GVHD uncovered by oligonucleotide microarrays.
Blood 2003;102(2):763-71.
2003: Baoan Ji; Xue-qing Chen; David E Misek; Rork Kuick; Samir Hanash; Stephen A Ernst; Rebecca Najarian; Craig D Logsdon
Pancreatic gene expression during the initiation of acute pancreatitis: identification of EGR-1 as a key regulator.
Physiological genomics 2003;14(1):59-72.
2003: Donald R Schwartz; Rong Wu; Sharon L R Kardia; Al Levin; Chiang-Ching Huang; Kerby Shedden; Rork Kuick; David E Misek; Samir M Hanash; Jeremy Taylor; Heather Reed; Neali Hendrix; Yali Zhai; Eric R Fearon; Kathleen R Cho
Novel candidate targets of beta-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas.
Cancer research 2003;63(11):2913-22.
2003: Craig D Logsdon; Diane M Simeone; Charles E Binkley; Thiruvengadam Arumugam; Joel K Greenson; Thomas J Giordano; David E Misek; Rork Kuick; Samir Hanash
Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer.
Cancer research 2003;63(10):2649-57.
2003: Rong Wu; Lin Lin; David G Beer; Lora Hedrick Ellenson; Barbara J Lamb; Jean-Marie Rouillard; Rork Kuick; Samir Hanash; Donald R Schwartz; Eric R Fearon; Kathleen R Cho
Amplification and overexpression of the L-MYC proto-oncogene in ovarian carcinomas.
The American journal of pathology 2003;162(5):1603-10.
2003: Guoan Chen; Tarek G Gharib; Dafydd Thomas; Chiang-Ching Huang; David E Misek; Rork Kuick; Thomas J Giordano; Mark D Iannettoni; Mark B Orringer; Samir M Hanash; David G Beer
Proteomic analysis of eIF-5A in lung adenocarcinomas.
Proteomics 2003;3(4):496-504.
2003: Guoan Chen; Hong Wang; Tarek G Gharib; Chiang-Ching Huang; Dafydd Thomas; Kerby Shedden; Rork Kuick; Jeremy Taylor; Sharon L R Kardia; David E Misek; Thomas J Giordano; Mark D Iannettoni; Mark B Orringer; Samir M Hanash; David G Beer
Overexpression of oncoprotein 18 correlates with poor differentiation in lung adenocarcinomas.
Molecular & cellular proteomics : MCP 2003;2(2):107-16.
2003: Thomas J Giordano; Dafydd Thomas; Rork Kuick; Michelle L Lizyness; David E Misek; Angela L Smith; Donita Sanders; Rima T Aljundi; Paul G Gauger; Norman W Thompson; Jeremy Taylor; Samir M Hanash
Distinct transcriptional profiles of adrenocortical tumors uncovered by DNA microarray analysis.
The American journal of pathology 2003;162(2):521-31.
2003: Chad J Creighton; Rork Kuick; David E Misek; David S Rickman; Franck Brichory; Jean-Marie Rouillard; Gilbert S Omenn; Samir Hanash
Profiling of pathway-specific changes in gene expression following growth of human cancer cell lines transplanted into mice.
Genome biology 2003;4(7):R46.
2002: Takao Hinoi; Peter C Lucas; Rork Kuick; Samir Hanash; Kathleen R Cho; Eric R Fearon
CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia.
Gastroenterology 2002;123(5):1565-77.
2002: John Tra; Tadashi Kondo; Qianjin Lu; Rork Kuick; Samir Hanash; Bruce C Richardson
Infrequent occurrence of age-dependent changes in CpG island methylation as detected by restriction landmark genome scanning.
Mechanisms of ageing and development 2002;123(11):1487-503.
2002: David E Misek; Christina L Chang; Rork Kuick; Robert Hinderer; Thomas J Giordano; David G Beer; Samir M Hanash
Transforming properties of a Q18-->E mutation of the microtubule regulator Op18.
Cancer cell 2002;2(3):217-28.
2002: Xiaoxiang Zhu; Katharina Wimmer; Rork Kuick; Barbara J Lamb; Stephanie Motyka; Rama Jasty; Valerie P Castle; Samir M Hanash
N-myc modulates expression of p73 in neuroblastoma.
Neoplasia (New York, N.Y.) 2002;4(5):432-9.
2002: Donald R Schwartz; Sharon L R Kardia; Kerby Shedden; Rork Kuick; George Michailidis; Jeremy Taylor; David E Misek; Rong Wu; Yali Zhai; Danielle M Darrah; Heather Reed; Lora Hedrick Ellenson; Thomas J Giordano; Eric R Fearon; Samir M Hanash; Kathleen R Cho
Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas.
Cancer research 2002;62(16):4722-9.
2002: Sarah E Ross; Robin L Erickson; Isabelle Gerin; Paul M DeRose; Laszlo Bajnok; Kenneth Longo; David E Misek; Rork Kuick; Samir M Hanash; Kevin Atkins; Sissel M Andresen; Hilde I Nebb; Lise Madsen; Karsten Kristiansen; Ormond A MacDougald
Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism.
Molecular and cellular biology 2002;22(16):5989-99.
2002: David G Beer; Sharon L R Kardia; Chiang-Ching Huang; Thomas J Giordano; Al Levin; David E Misek; Lin Lin; Guoan Chen; Tarek G Gharib; Dafydd Thomas; Michelle L Lizyness; Rork Kuick; Satoru Hayasaka; Jeremy Taylor; Mark D Iannettoni; Mark B Orringer; Samir Hanash
Gene-expression profiles predict survival of patients with lung adenocarcinoma.
Nature medicine 2002;8(8):816-24.
2002: Janet Y Leung; Frank T Kolligs; Rong Wu; Yali Zhai; Rork Kuick; Samir Hanash; Kathleen R Cho; Eric R Fearon
Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling.
The Journal of biological chemistry 2002;277(24):21657-65.
2002: Ji-yao Li; Pascal A Lescure; David E Misek; Yu-Mei Lai; Biaoxin Chai; Rork Kuick; Robert C Thompson; Rebecca M Demo; David M Kurnit; George Michailidis; Samir M Hanash; Ira Gantz
Food deprivation-induced expression of minoxidil sulfotransferase in the hypothalamus uncovered by microarray analysis.
The Journal of biological chemistry 2002;277(11):9069-76.
2002: Katharina Wimmer; Xiao-xiang Zhu Xx; Jean-Marie Rouillard; Peter F Ambros; Barbara J Lamb; Rork Kuick; Markus Eckart; Andreas Weinhaeusel; Christa Fonatsch; Samir M Hanash
Combined restriction landmark genomic scanning and virtual genome scans identify a novel human homeobox gene, ALX3, that is hypermethylated in neuroblastoma.
Genes, chromosomes & cancer 2002;33(3):285-94.
2002: Samir M Hanash; Miroslav P Bobek; David S Rickman; Tom Williams; Jean-Marie Rouillard; Rork Kuick; Eric Puravs
Integrating cancer genomics and proteomics in the post-genome era.
Proteomics 2002;2(1):69-75.
2001: Melanie Ehrlich; K L Buchanan; F Tsien; Guanchao Jiang; B Sun; William C Uicker; Corry M R Weemaes; Dominique Smeets; Karl Sperling; B H Belohradsky; Niels Tommerup; David E Misek; Jean-Marie Rouillard; Rork Kuick; Samir M Hanash
DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes.
Human molecular genetics 2001;10(25):2917-31.
2001: J M Oh; Franck Brichory; Eric Puravs; Rork Kuick; C Wood; Jean-Marie Rouillard; John Tra; S Kardia; David G Beer; Samir Hanash
A database of protein expression in lung cancer.
Proteomics 2001;1(10):1303-19.
2001: Thomas J Giordano; Kerby Shedden; Donald R Schwartz; Rork Kuick; Jeremy Taylor; N Lee; David E Misek; Joel K Greenson; Sharon L R Kardia; David G Beer; Gad Rennert; Kathleen R Cho; Stephen B Gruber; Eric R Fearon; Samir Hanash
Organ-specific molecular classification of primary lung, colon, and ovarian adenocarcinomas using gene expression profiles.
The American journal of pathology 2001;159(4):1231-8.
2001: David S Rickman; Miroslav P Bobek; David E Misek; Rork Kuick; Mila Blaivas; David M Kurnit; Jeremy Taylor; Samir M Hanash
Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis.
Cancer research 2001;61(18):6885-91.
2001: Jean-Marie Rouillard; Ayse E Erson; Rork Kuick; Jun-ichi Asakawa; Katharina Wimmer; Martine Muleris; Elizabeth M Petty; Samir Hanash
Virtual genome scan: a tool for restriction landmark-based scanning of the human genome.
Genome research 2001;11(8):1453-9.
2001: Katharina Wimmer; XX Zhu; Barbara J Lamb; Rork Kuick; Peter F Ambros; Heinrich Kovar; Didier Thoraval; A Elkahloun; P Meltzer; Samir M Hanash
Two-dimensional DNA electrophoresis identifies novel CpG islands frequently coamplified with MYCN in neuroblastoma.
Medical and pediatric oncology 2001;36(1):75-9.
2000: Lin Lin; Michael S Prescott; Zhaowen Zhu; P Singh; SY Chun; Rork Kuick; Samir M Hanash; Mark B Orringer; Thomas W Glover; David G Beer
Identification and characterization of a 19q12 amplicon in esophageal adenocarcinomas reveals cyclin E as the best candidate gene for this amplicon.
Cancer research 2000;60(24):7021-7.
2000: T Kondo; Miroslav P Bobek; Rork Kuick; B Lamb; X Zhu; Ajita Narayan; Déborah Bourc'his; Evani Viegas-Péquignot; M Ehrlich; Samir M Hanash
Whole-genome methylation scan in ICF syndrome: hypomethylation of non-satellite DNA repeats D4Z4 and NBL2.
Human molecular genetics 2000;9(4):597-604.
1999: Xiaoxiang Zhu; Chun Deng; Rork Kuick; Raymond L Yung; Barbara J Lamb; James V Neel; Bruce C Richardson; Samir Hanash
Analysis of human peripheral blood T cells and single-cell-derived T cell clones uncovers extensive clonal CpG island methylation heterogeneity throughout the genome.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):8058-63.
1999: Oliver S Soldes; Rork Kuick; I A Thompson; SJ Hughes; Mark B Orringer; Mark D Iannettoni; S M Hanash; David G Beer
Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas.
British journal of cancer 1999;79(3-4):595-603.
1999: Katharina Wimmer; XX Zhu; Barbara J Lamb; Rork Kuick; Peter F Ambros; Heinrich Kovar; Didier Thoraval; S Motyka; J R Alberts; Samir M Hanash
Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma.
Oncogene 1999;18(1):233-8.
1998: S J Hughes; Thomas W Glover; XX Zhu; Rork Kuick; Didier Thoraval; Mark B Orringer; David G Beer; Samir Hanash
A novel amplicon at 8p22-23 results in overexpression of cathepsin B in esophageal adenocarcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12410-5.
1998: L J Curtis; Y Li; Michelle Gerbault-Seureau; Rork Kuick; Anne-Marie Dutrillaux; Gérard Goubin; J Fawcett; S Cram; Bernard Dutrillaux; Samir Hanash; Martine Muleris
Amplification of DNA sequences from chromosome 19q13.1 in human pancreatic cell lines.
Genomics 1998;53(1):42-55.
1997: R Melhem; N Hailat; Rork Kuick; Samir M Hanash
Quantitative analysis of Op18 phosphorylation in childhood acute leukemia.
Leukemia 1997;11(10):1690-5.
1997: Luis Alberto Diaz; A W Friedman; X He; Rork Kuick; S M Hanash; David A Fox
Monocyte-dependent regulation of T lymphocyte activation through CD98.
International immunology 1997;9(9):1221-31.
1997: Katharina Wimmer; Didier Thoraval; Rork Kuick; Barbara J Lamb; Samir M Hanash
Identification of amplifications, deletions and methylation changes in cancer by means of two-dimensional analysis of genomic digests: application to neuroblastoma.
Biochemical Society transactions 1997;25(1):262-7.
1996: Katharina Wimmer; Didier Thoraval; J Asakawa; Rork Kuick; M Kodaira; Barbara J Lamb; J Fawcett; Thomas W Glover; S Cram; S Hanash
Two-dimensional separation and cloning of chromosome 1 NotI-EcoRV-derived genomic fragments.
Genomics 1996;38(2):124-32.
1996: Didier Thoraval; J Asakawa; Katharina Wimmer; Rork Kuick; Barbara J Lamb; Bruce C Richardson; Peter F Ambros; Thomas W Glover; S Hanash
Demethylation of repetitive DNA sequences in neuroblastoma.
Genes, chromosomes & cancer 1996;17(4):234-44.
1996: Katharina Wimmer; Rork Kuick; Didier Thoraval; S M Hanash
Two-dimensional separations of the genome and proteome of neuroblastoma cells.
Electrophoresis 1996;17(11):1741-51.
1996: Rork Kuick; J Asakawa; James V Neel; M Kodaira; C Satoh; Didier Thoraval; I L Gonzalez; S M Hanash
Studies of the inheritance of human ribosomal DNA variants detected in two-dimensional separations of genomic restriction fragments.
Genetics 1996;144(1):307-16.
1996: C Satoh; N Takahashi; J Asakawa; M Kodaira; Rork Kuick; S M Hanash; James V Neel
Genetic analysis of children of atomic bomb survivors.
Environmental health perspectives 1996;104 Suppl 3():511-9.
1996: Didier Thoraval; J Asakawa; M Kodaira; C Chang; Eric H. Radany; Rork Kuick; Barbara J Lamb; Bruce C Richardson; James V Neel; Thomas W Glover; S Hanash
A methylated human 9-kb repetitive sequence on acrocentric chromosomes is homologous to a subtelomeric repeat in chimpanzees.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4442-7.
1995: J Asakawa; Rork Kuick; James V Neel; M Kodaira; C Satoh; S M Hanash
Quantitative and qualitative genetic variation in two-dimensional DNA gels of human lymphocytoid cell lines.
Electrophoresis 1995;16(2):241-52.
1995: Rork Kuick; J Asakawa; James V Neel; C Satoh; S M Hanash
High yield of restriction fragment length polymorphisms in two-dimensional separations of human genomic DNA.
Genomics 1995;25(2):345-53.
1994: J Asakawa; Rork Kuick; James V Neel; M Kodaira; C Satoh; S M Hanash
Genetic variation detected by quantitative analysis of end-labeled genomic DNA fragments.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):9052-6.
1994: D R Ungar; N Hailat; J R Strahler; Rork Kuick; G M Brodeur; Robert C Seeger; Charles Patrick Reynolds; S M Hanash
Hsp27 expression in neuroblastoma: correlation with disease stage.
Journal of the National Cancer Institute 1994;86(10):780-4.
1993: S M Hanash; J R Strahler; Y Chan; Rork Kuick; D Teichroew; James V Neel; N Hailat; D R Keim; J Gratiot-Deans; D Ungar
Data base analysis of protein expression patterns during T-cell ontogeny and activation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3314-8.
1993: D R Keim; N Hailat; Rork Kuick; Charles Patrick Reynolds; G M Brodeur; Robert C Seeger; S M Hanash
PCNA levels in neuroblastoma are increased in tumors with an amplified N-myc gene and in metastatic stage tumors.
Clinical & experimental metastasis 1993;11(1):83-90.
1992: J R Strahler; N Hailat; Barbara J Lamb; K P Rogers; J A Underhill; R F Melhem; D R Keim; X Zhu; Rork Kuick; David A Fox
Activation of resting peripheral blood lymphocytes through the T cell receptor induces rapid phosphorylation of Op18.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(4):1191-8.
1992: Rork Kuick; James V Neel; J R Strahler; E H Chu; R Bargal; David A Fox; S M Hanash
Similarity of spontaneous germinal and in vitro somatic cell mutation rates in humans: implications for carcinogenesis and for the role of exogenous factors in "spontaneous" germinal mutagenesis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):7036-40.
1991: I Ali; Y Chan; Rork Kuick; D Teichroew; S M Hanash
Implementation of a two-dimensional electrophoresis-related laboratory information processing system: database aspects.
Electrophoresis 1991;12(10):747-61.
1991: Rork Kuick; M M Skolnick; S M Hanash; James V Neel
A two-dimensional electrophoresis-related laboratory information processing system: spot matching.
Electrophoresis 1991;12(10):736-46.
1991: Angelika Görg; W Postel; C Friedrich; Rork Kuick; J R Strahler; S M Hanash
Temperature-dependent spot positional variability in two-dimensional polypeptide patterns.
Electrophoresis 1991;12(9):653-8.
1991: J R Strahler; Rork Kuick; S M Hanash
Diminished phosphorylation of a heat shock protein (HSP 27) in infant acute lymphoblastic leukemia.
Biochemical and biophysical research communications 1991;175(1):134-42.
1990: J R Strahler; Rork Kuick; C Eckerskorn; F Lottspeich; Bruce C Richardson; David A Fox; Lloyd M Stoolman; C A Hanson; D Nichols; H J Tueche
Identification of two related markers for common acute lymphoblastic leukemia as heat shock proteins.
The Journal of clinical investigation 1990;85(1):200-7.
1989: S M Hanash; Rork Kuick; J Strahler; Bruce C Richardson; G Reaman; Lloyd M Stoolman; C Hanson; D Nichols; H J Tueche
Identification of a cellular polypeptide that distinguishes between acute lymphoblastic leukemia in infants and in older children.
Blood 1989;73(2):527-32.
1988: S M Hanash; Rork Kuick; D Nichols; Lloyd M Stoolman
Quantitative analysis of a new marker for common acute lymphoblastic leukemia detected by two-dimensional electrophoresis.
Disease markers 1988;6(4):209-20.
1988: S M Hanash; J R Strahler; Rork Kuick; E H Chu; D Nichols
Identification of a polypeptide associated with the malignant phenotype in acute leukemia.
The Journal of biological chemistry 1988;263(26):12813-5.
1988: E H Chu; M Boehnke; S M Hanash; Rork Kuick; Barbara J Lamb; James V Neel; W Niezgoda; S Pivirotto; G Sundling
Estimation of mutation rates based on the analysis of polypeptide constituents of cultured human lymphoblastoid cells.
Genetics 1988;119(3):693-703.
1988: Rork Kuick; S M Hanash; J R Strahler
Somatic mutation studies in human lymphoid cells: the detectability of quantitative genetic variants in two-dimensional gels.
Electrophoresis 1988;9(4):192-8.
1988: S M Hanash; M Boehnke; E H Chu; James V Neel; Rork Kuick
Nonrandom distribution of structural mutants in ethylnitrosourea-treated cultured human lymphoblastoid cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(1):165-9.
1988: Angelika Görg; W Postel; S Günther; J Weser; J R Strahler; S M Hanash; L Somerlot; Rork Kuick
Approach to stationary two-dimensional pattern: influence of focusing time and immobiline/carrier ampholytes concentrations.
Electrophoresis 1988;9(1):37-46.
1987: S M Hanash; E H Chu; Rork Kuick; M Skolnick; James V Neel; J Strahler; S Pivirotto; W Niezgoda
Detection of human somatic cell structural gene mutations by two-dimensional electrophoresis.
Proteins 1987;2(1):13-9.