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Myles Brown

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Min Ni; Yiwen Chen; Teng Fei; Dan Li; Elgene Lim; X Shirley Liu; Myles Brown
Amplitude modulation of androgen signaling by c-MYC.
Kexin Xu; Steven P Balk; Changmeng Cai; Laura Cato; Richard I Gregory; Anna C Groner; Housheng Hansen He; Philip W Kantoff; Rosina T Lis; Tao Liu; X Shirley Liu; Massimo Loda; Cristina Magi-Galluzzi; Rodolfo Montironi; Colm Morrissey; Edward C Stack; James E Thornton; Robert L Vessella; Xiaoqiu Wu; Zhenhua Jeremy Wu; Han Xu; Myles Brown
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent.
Shannon T Bailey; Xiaole Shirley Liu; Hyunjin Shin; Thomas Westerling; Myles Brown
Estrogen receptor prevents p53-dependent apoptosis in breast cancer.

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All Publications

2013: Min Ni; Yiwen Chen; Teng Fei; Dan Li; Elgene Lim; X Shirley Liu; Myles Brown
Amplitude modulation of androgen signaling by c-MYC.
Genes & development 2013;27(7):734-48.
2012: Kexin Xu; Steven P Balk; Changmeng Cai; Laura Cato; Richard I Gregory; Anna C Groner; Housheng Hansen He; Philip W Kantoff; Rosina T Lis; Tao Liu; X Shirley Liu; Massimo Loda; Cristina Magi-Galluzzi; Rodolfo Montironi; Colm Morrissey; Edward C Stack; James E Thornton; Robert L Vessella; Xiaoqiu Wu; Zhenhua Jeremy Wu; Han Xu; Myles Brown
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent.
Science (New York, N.Y.) 2012;338(6113):1465-9.
2012: Shannon T Bailey; Xiaole Shirley Liu; Hyunjin Shin; Thomas Westerling; Myles Brown
Estrogen receptor prevents p53-dependent apoptosis in breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(44):18060-5.
2012: Tong Sun; Ming Yang; Gwo-Shu Mary Lee; Mark Pomerantz; Steven Balk; Myles Brown; Shaoyong Chen; Chen-Lin Hsieh; Philip W Kantoff
The altered expression of MiR-221/-222 and MiR-23b/-27b is associated with the development of human castration resistant prostate cancer.
The Prostate 2012;72(10):1093-103.
2012: Housheng Hansen He; V Craig Jordan; Myles Brown; Mei Wei Chen; Clifford A Meyer; X Shirley Liu
Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics.
Genome research 2012;22(6):1015-25.
2011: Min Ni; David L Rimm; Hallie Wimberly; X Shirley Liu; Shannon T Bailey; Yiwen Chen; Yuuki Imai; Elgene Lim; Myles Brown
Targeting androgen receptor in estrogen receptor-negative breast cancer.
Cancer cell 2011;20(1):119-31.
2011: Clifford A Meyer; Myles Brown; Housheng H He; X Shirley Liu
BINOCh: binding inference from nucleosome occupancy changes.
Bioinformatics (Oxford, England) 2011;27(13):1867-8.
2011: Ming Yang; Steven Balk; Myles Brown; William Douglas Figg; Matthew Freedman; Gwo-Shu Mary Lee; Elahe Mostaghel; Mari Nakabayashi; William K Oh; Mark M Pomerantz; Meredith Regan; Robert Ross; Nima Sharifi; Tong Sun; Mary-Ellen Taplin; Lillian Werner; Wanling Xie; Philip W Kantoff
SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(18):2565-73.
2011: Richard Flavin; Jennifer Cook; Michelangelo Fiorentino; Dyane Bailey; Myles Brown; Massimo F Loda
β-Catenin is a useful adjunct immunohistochemical marker for the diagnosis of pulmonary lymphangioleiomyomatosis.
American journal of clinical pathology 2011;135(5):776-82.
2011: Aurélien A Sérandour; Stéphane Avner; Frédéric Percevault; Florence Demay; Maud Bizot; Céline Lucchetti-Miganeh; Frédérique Barloy-Hubler; Myles Brown; Mathieu Lupien; Raphaël Métivier; Gilles Salbert; Jérôme Eeckhoute
Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers.
Genome research 2011;21(4):555-65.
2011: Daniel E Frigo; Matthew K Howe; Bryan M Wittmann; Abigail M Brunner; Ian Cushman; Qianben Wang; Myles Brown; Anthony R Means; Donald P McDonnell
CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells.
Cancer research 2011;71(2):528-37.
2011: Tao Liu; Myles Brown; Yiwen Chen; Bernett Lee; Ying Lei; Jian Ma; Clifford A Meyer; Jorge A Ortiz; Utz J Pape; Michael Poidinger; Hyunjin Shin; Len Taing; Yaron Turpaz; Swee S Wong; Kevin Yeung; Yong Zhang; X Shirley Liu
Cistrome: an integrative platform for transcriptional regulation studies.
Genome biology 2011;12(8):R83.
2010: Michael P Verzi; Hyunjin Shin; H Hansen He; Rita Sulahian; Clifford A Meyer; Robert K Montgomery; James C Fleet; Myles Brown; X Shirley Liu; Ramesh A Shivdasani
Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2.
Developmental cell 2010;19(5):713-26.
2010: Mathieu Lupien; Clifford A Meyer; Shannon T Bailey; Jérôme Eeckhoute; Jennifer Cook; Thomas Westerling; Xiaoyang Zhang; Jason S Carroll; Daniel R Rhodes; X Shirley Liu; Myles Brown
Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistance.
Genes & development 2010;24(19):2219-27.
2010: Michael P Verzi; Pantelis Hatzis; Rita Sulahian; Juliet Philips; Jurian Schuijers; Hyunjin Shin; Ellen Freed; John P Lynch; Duyen T Dang; Myles Brown; Hans Clevers; X Shirley Liu; Ramesh A Shivdasani
TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(34):15157-62.
2010: Nasim Ahmadiyeh; Mark M Pomerantz; Chiara Grisanzio; Paula Herman; Li Jia; VANESSA ALMENDRO; Housheng Hansen He; Myles Brown; X Shirley Liu; Matt Davis; Jennifer L Caswell; Christine A Beckwith; Adam Hills; Laura Macconaill; Gerhard A Coetzee; Meredith M Regan; Matthew L Freedman
8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(21):9742-6.
2010: Maria Torres-Arzayus; Jin Zhao; Roderick Bronson; Myles Brown
Estrogen-dependent and estrogen-independent mechanisms contribute to AIB1-mediated tumor formation.
Cancer research 2010;70(10):4102-11.
2010: Hilary E Wade; Sakiko Kobayashi; Matthew L Eaton; Michelle S Jansen; Edward K Lobenhofer; Mathieu Lupien; Timothy R Geistlinger; Wencheng Zhu; Joseph R Nevins; Myles Brown; Deborah C Otteson; Donald P McDonnell
Multimodal regulation of E2F1 gene expression by progestins.
Molecular and cellular biology 2010;30(8):1866-77.
2010: Anita Wolfer; Ben S Wittner; daniel irimia; Richard J Flavin; Mathieu Lupien; Ruwanthi N Gunawardane; Clifford A Meyer; Eric S Lightcap; Pablo Tamayo; Jill P Mesirov; X Shirley Liu; Toshi Shioda; Mehmet Toner; Massimo Loda; Myles Brown; Joan S Brugge; Sridhar Ramaswamy
MYC regulation of a "poor-prognosis" metastatic cancer cell state.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(8):3698-703.
2009: Qing Zhang; Jinming Gu; Lianjie Li; Jiayun Liu; Biao Luo; Hiu Wing Cheung; Jesse S Boehm; Min Ni; Christoph Geisen; David E Root; Kornelia Polyak; Myles Brown; Andrea L Richardson; William C Hahn; William G Kaelin; Archana Bommi-Reddy
Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase.
Cancer cell 2009;16(5):413-24.
2009: Joanna Boros; Ian J Donaldson; Amanda O'Donnell; Zaneta A Odrowaz; Leo A H Zeef; Mathieu Lupien; Clifford A Meyer; X Shirley Liu; Myles Brown; Andrew D Sharrocks
Elucidation of the ELK1 target gene network reveals a role in the coordinate regulation of core components of the gene regulation machinery.
Genome research 2009;19(11):1963-73.
2009: Daniel E Frigo; Andrea B Sherk; Bryan M Wittmann; John D Norris; Qianben Wang; James D Joseph; Aidan P Toner; Myles Brown; Donald P McDonnell
Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro.
Molecular endocrinology (Baltimore, Md.) 2009;23(9):1385-96.
2009: Poornima Bhat-Nakshatri; Guohua Wang; Nikail R Collins; Michael J Thomson; Tim R Geistlinger; Jason S Carroll; Myles Brown; Scott M Hammond; Edward F Srour; Yunlong Liu; Harikrishna Nakshatri
Estradiol-regulated microRNAs control estradiol response in breast cancer cells.
Nucleic acids research 2009;37(14):4850-61.
2009: Qianben Wang; Wei Li; Yong Zhang; Xin Yuan; Kexin Xu; Jindan YU; Zhong Chen; Rameen Beroukhim; Hongyun Wang; Mathieu Lupien; Tao Wu; Meredith M Regan; Clifford A Meyer; Jason S Carroll; Arjun Kumar Manrai; Olli A Jänne; Steven P Balk; Rohit Mehra; Bo Han; Arul M Chinnaiyan; Mark A Rubin; Lawrence True; Michelangelo Fiorentino; Christopher Fiore; Massimo Loda; Philip W Kantoff; X Shirley Liu; Myles Brown
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer.
Cell 2009;138(2):245-56.
2009: Carmelo Nucera; Jerome Eeckhoute; Stephen Finn; Jason S Carroll; Azra H Ligon; Carmen Priolo; Guido Fadda; Mary Toner; Orla Sheils; Marco Attard; Alfredo Pontecorvi; Vania Nose; Massimo Loda; Myles Brown
FOXA1 is a potential oncogene in anaplastic thyroid carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(11):3680-9.
2009: Mathieu Lupien; Myles Brown
Cistromics of hormone-dependent cancer.
Endocrine-related cancer 2009;16(2):381-9.
2009: Mathieu Lupien; Jérôme Eeckhoute; Clifford A Meyer; Susan A Krum; Daniel R Rhodes; X Shirley Liu; Myles Brown
Coactivator function defines the active estrogen receptor alpha cistrome.
Molecular and cellular biology 2009;29(12):3413-23.
2009: Tong Sun; Qianben Wang; Steven Balk; Myles Brown; Gwo-Shu Mary Lee; Philip Kantoff
The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines.
Cancer research 2009;69(8):3356-63.
2009: Jerome C Nwachukwu; Paolo Mita; Rachel Ruoff; Susan Ha; Qianben Wang; S Joseph Huang; Samir S Taneja; Myles Brown; William L Gerald; Michael J Garabedian; Susan K Logan
Genome-wide impact of androgen receptor trapped clone-27 loss on androgen-regulated transcription in prostate cancer cells.
Cancer research 2009;69(7):3140-7.
2009: Xiaobo Xia; Madeleine E Lemieux; Wei LI; Jason S Carroll; Myles Brown; X Shirley Liu; Andrew L Kung
Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(11):4260-5.
2009: Jérôme Eeckhoute; Mathieu Lupien; Clifford A Meyer; Michael P Verzi; Ramesh A Shivdasani; X Shirley Liu; Myles Brown
Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers.
Genome research 2009;19(3):372-80.
2009: Jérôme Eeckhoute; Mathieu Lupien; Myles Brown
Combining chromatin immunoprecipitation and oligonucleotide tiling arrays (ChIP-Chip) for functional genomic studies.
Methods in molecular biology (Clifton, N.J.) 2009;556():155-64.
2008: Antoni Hurtado; Kelly A Holmes; Timothy R Geistlinger; Iain R Hutcheson; Robert I Nicholson; Myles Brown; Jie Jiang; William J Howat; Simak Ali; Jason S Carroll
Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen.
Nature 2008;456(7222):663-6.
2008: Poornima Bhat-Nakshatri; Guohua Wang; APPAIAH N HITESH; Nikhil Luktuke; Jason S Carroll; Tim R Geistlinger; Myles Brown; Sunil Badve; Yunlong Liu; Harikrishna Nakshatri
AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer.
Molecular and cellular biology 2008;28(24):7487-503.
2008: Susan A Krum; Gustavo A Miranda-Carboni; Mathieu Lupien; Jérôme Eeckhoute; Jason S Carroll; Myles Brown
Unique ERalpha cistromes control cell type-specific gene regulation.
Molecular endocrinology (Baltimore, Md.) 2008;22(11):2393-406.
2008: Irina U Agoulnik; William E Bingman; Manjula Nakka; Wei LI; Qianben Wang; X Shirley Liu; Myles Brown; Nancy L Weigel
Target gene-specific regulation of androgen receptor activity by p42/p44 mitogen-activated protein kinase.
Molecular endocrinology (Baltimore, Md.) 2008;22(11):2420-32.
2008: Kelly A Holmes; Jun S Song; Xiaole S Liu; Myles Brown; Jason S Carroll
Nkx3-1 and LEF-1 function as transcriptional inhibitors of estrogen receptor activity.
Cancer research 2008;68(18):7380-5.
2008: Sunita R Setlur; Kirsten D Mertz; Yujin Hoshida; Francesca Demichelis; Mathieu Lupien; Sven Perner; Andrea Sboner; Yudi Pawitan; Ove Andrén; Laura A Johnson; Jeff Tang; Hans-Olov Adami; Stefano Calza; Arul M Chinnaiyan; Daniel R Rhodes; Scott A Tomlins; Katja Fall; Lorelei A Mucci; Philip W Kantoff; Meir J Stampfer; Swen-Olof Andersson; Eberhard Varenhorst; Jan-Erik Johansson; Myles Brown; Todd R Golub; Mark A Rubin
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.
Journal of the National Cancer Institute 2008;100(11):815-25.
2008: Bo-Ying Bao; Bin-Fay Chuang; Qianben Wang; Oliver Sartor; Steven P Balk; Myles Brown; Philip W Kantoff; Gwo-Shu Mary Lee
Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.
The Prostate 2008;68(8):839-48.
2008: Susan A Krum; Myles Brown
Unraveling estrogen action in osteoporosis.
Cell cycle (Georgetown, Tex.) 2008;7(10):1348-52.
2008: Xavier Leleu; Jérôme Eeckhoute; Xiaoying Jia; Aldo Roccaro; Anne-Sophie Moreau; Mena Farag; Antonio Sacco; Hai T Ngo; Judith M Runnels; Molly R Melhem; Nicolas Burwick; Abdelkareem Azab; Feda Azab; Zachary Hunter; Evdoxia Hatjiharissi; Daniel R Carrasco; Steve P Treon; Thomas E Witzig; Teru Hideshima; Myles Brown; Kenneth C Anderson; Irene M Ghobrial
Targeting NF-kappaB in Waldenstrom macroglobulinemia.
Blood 2008;111(10):5068-77.
2008: Xiuwei H Yang; Andrea L Richardson; Maria Torres-Arzayus; Pengcheng Zhou; Chandan Sharma; Alexander R Kazarov; Milena M Andzelm; Jack L Strominger; Myles Brown; Martin Helmer
CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization.
Cancer research 2008;68(9):3204-13.
2008: Mathieu Lupien; Jérôme Eeckhoute; Clifford A Meyer; Qianben Wang; Yong Zhang; Wei Li; Jason S Carroll; Xiaole (Shirley) Liu; Myles Brown
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription.
Cell 2008;132(6):958-70.
2008: David S Johnson; Wei LI; D Benjamin Gordon; Arindam Bhattacharjee; Bo Curry; Jayati Ghosh; leonardo brizuela; Jason S Carroll; Myles Brown; Paul Flicek; Christoph M Koch; Ian Dunham; Mark Bieda; Xiaoqin Xu; Peggy J Farnham; Philipp Kapranov; David A Nix; Thomas Gingeras; Xinmin Zhang; Heather Holster; Nan Jiang; Roland D Green; Jun S Song; Scott A McCuine; Elizabeth Anton; Loan Nguyen; Nathan D Trinklein; Zhen Ye; Keith Ching; David Hawkins; Bing Ren; Peter C Scacheri; Joel Rozowsky; Alexander Karpikov; Ghia Euskirchen; Sherman Weissman; Mark Gerstein; Michael Snyder; Annie Yang; Zarmik Moqtaderi; Heather A. Hirsch; Hennady P Shulha; Yutao Fu; Zhiping Weng; Kevin Struhl; Richard Myers; Jason Dillon Lieb; X Shirley Liu
Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets.
Genome research 2008;18(3):393-403.
2008: Susan A Krum; Gustavo A Miranda-Carboni; Peter V Hauschka; Jason S Carroll; Timothy F Lane; Leonard P Freedman; Myles Brown
Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival.
The EMBO journal 2008;27(3):535-45.
2008: Yong Zhang; Tao Liu; Clifford A Meyer; Jérôme Eeckhoute; David S Johnson; Bradley E Bernstein; Chad Nusbaum; Richard Myers; Myles Brown; Wei Li; Xiaole (Shirley) Liu
Model-based analysis of ChIP-Seq (MACS).
Genome biology 2008;9(9):R137.
2008: Wei Li; Jason S Carroll; Myles Brown; x Shirley Liu
xMAN: extreme MApping of OligoNucleotides.
BMC genomics 2008;9 Suppl 1():S20.
2008: Seth Frietze; Mathieu Lupien; Pamela A Silver; Myles Brown
CARM1 regulates estrogen-stimulated breast cancer growth through up-regulation of E2F1.
Cancer research 2008;68(1):301-6.
2007: Qianben Wang; Wei Li; Xiaole (Shirley) Liu; Jason S Carroll; Olli A Jänne; Erika Krasnickas Keeton; Arul M Chinnaiyan; Kenneth J Pienta; Myles Brown
A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth.
Molecular cell 2007;27(3):380-92.
2007: Jérôme Eeckhoute; Erika Krasnickas Keeton; Mathieu Lupien; Susan A Krum; Jason S Carroll; Myles Brown
Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer.
Cancer research 2007;67(13):6477-83.
2007: Mathieu Durand; Adrianne Kolpak; Timothy Farrell; Nathan A Elliott; Wenlin Shao; Myles Brown; Michael R Volkert
The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins.
BMC cell biology 2007;8():13.
2006: Maria Torres-Arzayus; Jing Yuan; Jamie L DellaGatta; Heidi Lane; Andrew L Kung; Myles Brown
Targeting the AIB1 oncogene through mammalian target of rapamycin inhibition in the mammary gland.
Cancer research 2006;66(23):11381-8.
2006: Jason S Carroll; Clifford A Meyer; Jun Song; Wei Li; Timothy Geistlinger; Jérôme Eeckhoute; Alexander S Brodsky; Erika Krasnickas Keeton; Kirsten C Fertuck; Giles F Hall; Qianben Wang; Stefan Bekiranov; Victor Sementchenko; Edward A Fox; Pamela A Silver; Thomas Gingeras; Xiaole (Shirley) Liu; Myles Brown
Genome-wide analysis of estrogen receptor binding sites.
Nature genetics 2006;38(11):1289-97.
2006: Jérôme Eeckhoute; Jason S Carroll; Timothy Geistlinger; Maria Torres-Arzayus; Myles Brown
A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer.
Genes & development 2006;20(18):2513-26.
2006: W Evan Johnson; Wei Li; Clifford A Meyer; Raphael Gottardo; Jason S Carroll; Myles Brown; Xiaole (Shirley) Liu
Model-based analysis of tiling-arrays for ChIP-chip.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12457-62.
2006: Jason S Carroll; Myles Brown
Estrogen receptor target gene: an evolving concept.
Molecular endocrinology (Baltimore, Md.) 2006;20(8):1707-14.
2006: Danielle K Carroll; Jason S Carroll; Chee-Onn Leong; Fang Cheng; Myles Brown; Alea A Mills; Joan S Brugge; Leif W Ellisen
p63 regulates an adhesion programme and cell survival in epithelial cells.
Nature cell biology 2006;8(6):551-61.
2006: Susan Colilla; Philip W Kantoff; Susan L Neuhausen; Andrew K Godwin; Mary B Daly; Steven A Narod; Judy E Garber; Henry T Lynch; Myles Brown; Barbara L Weber; Timothy R Rebbeck
The joint effect of smoking and AIB1 on breast cancer risk in BRCA1 mutation carriers.
Carcinogenesis 2006;27(3):599-605.
2006: Andrea L Richardson; Zhigang C Wang; Arcangela De Nicolo; Xin Lu; Myles Brown; alexander miron; Xiaodong Liao; J Dirk Iglehart; David M Livingston; Shridar Ganesan
X chromosomal abnormalities in basal-like human breast cancer.
Cancer cell 2006;9(2):121-32.
2006: Steven E Come; Aman U Buzdar; James N Ingle; Carlos L Arteaga; Myles Brown; Mitch Dowsett; Susan G Hilsenbeck; Rakesh Kumar; Stephen R D Johnston; Adrian V Lee; Soonmyung Paik; Kathleen I Pritchard; Eric P Winer; Carol Hart
Proceedings of the Fifth International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer: conference summary statement.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(3 Pt 2):997s-1000s.
2006: Qian-fei Wang; Shyam Prabhakar; Qianben Wang; Alan M Moses; Sumita Chanan; Myles Brown; Michael B Eisen; Jan-Fang Cheng; Edward M Rubin; Dario Boffelli
Primate-specific evolution of an LDLR enhancer.
Genome biology 2006;7(8):R68.
2005: Serban P Georgescu; Joyce H Li; Qing Lu; Richard H Karas; Myles Brown; Michael Mendelsohn
Modulator recognition factor 1, an AT-rich interaction domain family member, is a novel corepressor for estrogen receptor alpha.
Molecular endocrinology (Baltimore, Md.) 2005;19(10):2491-501.
2005: Qianben Wang; Jason S Carroll; Myles Brown
Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking.
Molecular cell 2005;19(5):631-42.
2005: Jason S Carroll; Xiaole (Shirley) Liu; Alexander S Brodsky; Wei Li; Clifford A Meyer; Anna J Szary; Jérôme Eeckhoute; Wenlin Shao; Eli V Hestermann; Timothy Geistlinger; Edward A Fox; Pamela A Silver; Myles Brown
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1.
Cell 2005;122(1):33-43.
2005: Erika Krasnickas Keeton; Myles Brown
Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT.
Molecular endocrinology (Baltimore, Md.) 2005;19(6):1543-54.
2005: Phillip G Febbo; Mark Lowenberg; Aaron R Thorner; Myles Brown; Massimo Loda; Todd R Golub
Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer.
The Journal of urology 2005;173(5):1772-7.
2004: Maria Torres-Arzayus; Jaime Font de Mora; Jing Yuan; Francisca Vazquez; Roderick Bronson; Montserrat Rue; William R Sellers; Myles Brown
High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene.
Cancer cell 2004;6(3):263-74.
2004: Wenlin Shao; Erika Krasnickas Keeton; Donald P McDonnell; Myles Brown
Coactivator AIB1 links estrogen receptor transcriptional activity and stability.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11599-604.
2004: Steven E Come; Aman U Buzdar; Carlos L Arteaga; Mina J Bissell; Myles Brown; Matthew J Ellis; Paul E Goss; Jeffrey E Green; James N Ingle; Adrian V Lee; Daniel Medina; Robert I Nicholson; Richard J Santen; Rachel Schiff; Carol S Hart
Proceedings of the Third International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(1 Pt 2):327S-330S.
2004: Wenlin Shao; Myles Brown
Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapy.
Breast cancer research : BCR 2004;6(1):39-52.
2003: Eli V Hestermann; Myles Brown
Agonist and chemopreventative ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor.
Molecular and cellular biology 2003;23(21):7920-5.
2003: Erika Krasnickas Keeton; Myles Brown
Coregulator expression and breast cancer: improving the predictive power of estrogen receptor alpha.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(4):1229-30.
2002: Peter R Carroll; Philip W Kantoff; Steven P Balk; Myles Brown; Anthony V D'amico; Daniel J George; Gary D Grossfeld; Candace S Johnson; W Kevin Kelly; Laurence Klotz; W Robert Lee; Deborah P Lubeck; David G Mcleod; William K Oh; Alan Pollack; Oliver Sartor; Matthew R Smith; Carol Hart
Overview consensus statement. Newer approaches to androgen deprivation therapy in prostate cancer.
Urology 2002;60(3 Suppl 1):1-6.
2002: Wenlin Shao; Shlomit Halachmi; Myles Brown
ERAP140, a conserved tissue-specific nuclear receptor coactivator.
Molecular and cellular biology 2002;22(10):3358-72.
2002: Yongfeng Shang; Myles Brown
Molecular determinants for the tissue specificity of SERMs.
Science (New York, N.Y.) 2002;295(5564):2465-8.
2002: Yongfeng Shang; Molly Myers; Myles Brown
Formation of the androgen receptor transcription complex.
Molecular cell 2002;9(3):601-10.
2002: Christopher A Haiman; Myles Brown; Susan E Hankinson; Donna Spiegelman; GRaham Colditz; Walter C Willett; Philip W Kantoff; David J Hunter
The androgen receptor CAG repeat polymorphism and risk of breast cancer in the Nurses' Health Study.
Cancer research 2002;62(4):1045-9.
2002: Christopher A Haiman; Susan E Hankinson; Donna Spiegelman; Myles Brown; David J Hunter
No association between a single nucleotide polymorphism in CYP19 and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(2):215-6.
2002: James DiRenzo; Sabina Signoretti; Noriaki Nakamura; Ramon Rivera-Gonzalez; William R Sellers; Massimo Loda; Myles Brown
Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line.
Cancer research 2002;62(1):89-98.
2001: Tetsuro Yahata; W Shao; H Endoh; Jingyung Hur; Kathryn R Coser; H Sun; Y Ueda; S Kato; Kurt J Isselbacher; Myles Brown; Toshi Shioda
Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein.
Genes & development 2001;15(19):2598-612.
2001: Timothy R Rebbeck; Yiting Wang; Philip W Kantoff; K Krithivas; Susan L Neuhausen; Andrew K Godwin; Mary B Daly; Steven A Narod; Jean-Sebastien Brunet; Danny Vesprini; Judy E Garber; Henry T Lynch; Barbara L Weber; Myles Brown
Modification of BRCA1- and BRCA2-associated breast cancer risk by AIB1 genotype and reproductive history.
Cancer research 2001;61(14):5420-4.
2000: Y Shang; X Hu; J DiRenzo; Mitchell Lazar; Myles Brown
Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription.
Cell 2000;103(6):843-52.
2000: J Font de Mora; Myles Brown
AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor.
Molecular and cellular biology 2000;20(14):5041-7.
2000: G Poelzl; Y Kasai; N Mochizuki; P W Shaul; Myles Brown; Michael Mendelsohn
Specific association of estrogen receptor beta with the cell cycle spindle assembly checkpoint protein, MAD2.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2836-9.
2000: Christopher A Haiman; Susan E Hankinson; Donna Spiegelman; GRaham Colditz; Walter C Willett; F E Speizer; Myles Brown; David J Hunter
Polymorphic repeat in AIB1 does not alter breast cancer risk.
Breast cancer research : BCR 2000;2(5):378-85.
1999: K Krithivas; S M Yurgalevitch; B A Mohr; C J Wilcox; S J Batter; Myles Brown; Christopher Longcope; J B McKinlay; Philip W Kantoff
Evidence that the CAG repeat in the androgen receptor gene is associated with the age-related decline in serum androgen levels in men.
The Journal of endocrinology 1999;162(1):137-42.
1999: Timothy R Rebbeck; Philip W Kantoff; K Krithivas; Susan L Neuhausen; M Anne Blackwood; Andrew K Godwin; Mary B Daly; Steven A Narod; Judy E Garber; Henry T Lynch; Barbara L Weber; Myles Brown
Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat.
American journal of human genetics 1999;64(5):1371-7.
1999: B Hanstein; H Liu; M C Yancisin; Myles Brown
Functional analysis of a novel estrogen receptor-beta isoform.
Molecular endocrinology (Baltimore, Md.) 1999;13(1):129-37.
1998: Phillip G Febbo; Philip W Kantoff; E Giovannucci; Myles Brown; G Chang; C H Hennekens; M Stampfer
Debrisoquine hydroxylase (CYP2D6) and prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(12):1075-8.
1998: Philip W Kantoff; E Giovannucci; Myles Brown
The androgen receptor CAG repeat polymorphism and its relationship to prostate cancer.
Biochimica et biophysica acta 1998;1378(3):C1-5.
1998: W Seol; B Hanstein; Myles Brown; David D Moore
Inhibition of estrogen receptor action by the orphan receptor SHP (short heterodimer partner).
Molecular endocrinology (Baltimore, Md.) 1998;12(10):1551-7.
1998: Elizabeth A Platz; Edward Giovannucci; DM Dahl; K Krithivas; Charles H Hennekens; Myles Brown; Meir J Stampfer; Philip W Kantoff
The androgen receptor gene GGN microsatellite and prostate cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(5):379-84.
1997: E Neuman; MH Ladha; Nancy U Lin; TM Upton; S J Miller; James DiRenzo; R G Pestell; Philip W Hinds; S F Dowdy; Myles Brown; Mark E Ewen
Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4.
Molecular and cellular biology 1997;17(9):5338-47.
1997: N Peloux; Myles Brown; A Sergeant
Human estrogen receptor (ER) gene promoter-P1: estradiol-independent activity and estradiol inducibility in ER+ and ER- cells.
Molecular endocrinology (Baltimore, Md.) 1997;11(9):1319-31.
1997: Edward Giovannucci; Meir J Stampfer; K Krithivas; Myles Brown; DM Dahl; A Brufsky; J Talcott; Charles H Hennekens; Philip W Kantoff
The CAG repeat within the androgen receptor gene and its relationship to prostate cancer.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3320-3.
1997: Philip W Kantoff; P G Febbo; Edward Giovannucci; K Krithivas; DM Dahl; G Chang; Charles H Hennekens; Myles Brown; Meir J Stampfer
A polymorphism of the 5 alpha-reductase gene and its association with prostate cancer: a case-control analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(3):189-92.
1997: Z Tang; I Treilleux; Myles Brown
A transcriptional enhancer required for the differential expression of the human estrogen receptor in breast cancers.
Molecular and cellular biology 1997;17(3):1274-80.
1996: B Hanstein; R Eckner; J DiRenzo; Shlomit Halachmi; H Liu; B Searcy; R Kurokawa; Myles Brown
p300 is a component of an estrogen receptor coactivator complex.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11540-5.
1996: Ralph Scully; S Ganesan; Myles Brown; J A De Caprio; S A Cannistra; Jean Feunteun; S Schnitt; David M Livingston
Location of BRCA1 in human breast and ovarian cancer cells.
Science (New York, N.Y.) 1996;272(5258):123-6.
1995: K Yu; W Bayona; CB Kallen; H P Harding; C P Ravera; G McMahon; Myles Brown; Mitchell Lazar
Differential activation of peroxisome proliferator-activated receptors by eicosanoids.
The Journal of biological chemistry 1995;270(41):23975-83.
1995: R Kurokawa; M Söderström; A Hörlein; Shlomit Halachmi; Myles Brown; Michael G Rosenfeld; Christopher K Glass
Polarity-specific activities of retinoic acid receptors determined by a co-repressor.
Nature 1995;377(6548):451-4.
1994: Shlomit Halachmi; E Marden; G Martin; H MacKay; C Abbondanza; Myles Brown
Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription.
Science (New York, N.Y.) 1994;264(5164):1455-8.
1994: Myles Brown
Estrogen receptor molecular biology.
Hematology/oncology clinics of North America 1994;8(1):101-12.
1993: James H Segars; Michael S Marks; S Hirschfeld; P H Driggers; E Martinez; J F Grippo; Myles Brown; Walter Wahli; Keiko Ozato
Inhibition of estrogen-responsive gene activation by the retinoid X receptor beta: evidence for multiple inhibitory pathways.
Molecular and cellular biology 1993;13(4):2258-68.
1991: J Kjems; Myles Brown; D D Chang; Phillip A Sharp
Structural analysis of the interaction between the human immunodeficiency virus Rev protein and the Rev response element.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(3):683-7.
1990: Myles Brown; Phillip A Sharp
Human estrogen receptor forms multiple protein-DNA complexes.
The Journal of biological chemistry 1990;265(19):11238-43.
1988: V Cherington; Myles Brown; E Paucha; J St Louis; Bruce M Spiegelman; Thomas M Roberts
Separation of simian virus 40 large-T-antigen-transforming and origin-binding functions from the ability to block differentiation.
Molecular and cellular biology 1988;8(3):1380-4.
1987: Myles Brown; J Figge; U Hansen; C Wright; K T Jeang; G Khoury; David M Livingston; Thomas M Roberts
lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells.
Cell 1987;49(5):603-12.
1987: I Bikel; X Montano; M E Agha; Myles Brown; M McCormack; J Boltax; David M Livingston
SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen.
Cell 1987;48(2):321-30.
1986: Myles Brown; M McCormack; K G Zinn; M P Farrell; I Bikel; David M Livingston
A recombinant murine retrovirus for simian virus 40 large T cDNA transforms mouse fibroblasts to anchorage-independent growth.
Journal of virology 1986;60(1):290-3.
1985: Dennis C Lynch; T S Zimmerman; C J Collins; Myles Brown; M J Morin; E H Ling; David M Livingston
Molecular cloning of cDNA for human von Willebrand factor: authentication by a new method.
Cell 1985;41(1):49-56.
1981: N Goldman; Myles Brown; G Khoury
Modification of SV40 T antigen by poly ADP-ribosylation.
Cell 1981;24(2):567-72.
1977: F J Ferdinand; Myles Brown; G Khoury
Characterization of early simian virus 40 transcriptional complexes: late transcription in the absence of detectable DNA replication.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(12):5443-7.
1977: J M Kuster; P T Mora; Myles Brown; G Khoury
Immunologic selection against simian virus-40 transformed cells: concomitnat loss of viral antigens and early viral gene sequences.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(11):4796-800.
1977: F J Ferdinand; Myles Brown; G Khoury
Synthesis and characterization of late lytic simian virus 40 RNA from transcriptional complexes.
Virology 1977;78(1):150-61.
1977: L J Rosenthal; Myles Brown
The control of SV40 transcription during a lytic infection: late RNA synthesis in the presence of inhibitors of DNA replication.
Nucleic acids research 1977;4(3):551-65.
1976: G Khoury; B J Carter; F J Ferdinand; Peter M Howley; Myles Brown; Malcolm Martin
Genome localization of simian virus 40 RNA species.
Journal of virology 1976;17(3):832-40.
1975: G Khoury; Peter M Howley; Myles Brown; Malcolm Martin
The detection and quantitation of SV40 nucleic acid sequences using single-stranded SV40 DNA probes.
Cold Spring Harbor symposia on quantitative biology 1975;39 Pt 1():147-52.
1969: S Kit; Myles Brown
Rescue of Simian Virus 40 from Cell Lines Transformed at High and at Low Input Multiplicities by Unirradiated or Ultraviolet-irradiated Virus.
Journal of virology 1969;4(3):226-30.