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Anastasia Nijnik

Research Profile

Chemicals & Drugs

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Physiology

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Immunomodulation

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Publications

TOP 3
Jason Kindrachuk; Shuhua Ma; Laure Magrangeas-Janot; Anastasia Nijnik; Mukesh Pasupuleti; Lisa Thorson; Manjeet Bains; Eefjan J Breukink; Donna M Easton; Melissa Elliott; Brett Finlay; Hans Georg-Sahl; Håvard Jenssen; Robert Ew Hancock
Manipulation of innate immunity by a bacterial secreted peptide: Lantibiotic nisin Z is selectively immunomodulatory.
Anastasia Nijnik; Claire Raisen; Ramiro Ramirez-Solis; Edward Ryder; Karen P Steel; Jacqueline K White; Mark Lucas; Lynda Mottram; Niels C Adams; Hibret Adissu; Jing Chen; Simon Clare; Gordon Dougan; Jeanne Estabel; Christine Hale; Robert E W Hancock
The role of sphingosine-1-phosphate transporter Spns2 in immune system function.
Robert E W Hancock; Anastasia Nijnik; Dana J Philpott
Modulating immunity as a therapy for bacterial infections.

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All Publications

2013: Jason Kindrachuk; Shuhua Ma; Laure Magrangeas-Janot; Anastasia Nijnik; Mukesh Pasupuleti; Lisa Thorson; Manjeet Bains; Eefjan J Breukink; Donna M Easton; Melissa Elliott; Brett Finlay; Hans Georg-Sahl; Håvard Jenssen; Robert Ew Hancock
Manipulation of innate immunity by a bacterial secreted peptide: Lantibiotic nisin Z is selectively immunomodulatory.
Innate immunity 2013;19(3):315-27.
2012: Anastasia Nijnik; Claire Raisen; Ramiro Ramirez-Solis; Edward Ryder; Karen P Steel; Jacqueline K White; Mark Lucas; Lynda Mottram; Niels C Adams; Hibret Adissu; Jing Chen; Simon Clare; Gordon Dougan; Jeanne Estabel; Christine Hale; Robert E W Hancock
The role of sphingosine-1-phosphate transporter Spns2 in immune system function.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(1):102-11.
2012: Robert E W Hancock; Anastasia Nijnik; Dana J Philpott
Modulating immunity as a therapy for bacterial infections.
Nature reviews. Microbiology 2012;10(4):243-54.
2012: Anastasia Nijnik; Jelena Pistolic; Alexander Ramin; Kenneth W Harder; Patricia Cho; Reza Falsafi; Niall C J Filewod; Robert E W Hancock
The role of the Src family kinase Lyn in the immunomodulatory activities of cathelicidin peptide LL-37 on monocytic cells.
Journal of leukocyte biology 2012;91(4):599-607.
2012: Anastasia Nijnik; Christine Podrini; Claire Raisen; Ramiro Ramirez-Solis; Jacqui K White; Kosuke Yusa; David J Adams; Niels Adams; Simon Clare; Jeanne Estabel; Aaron R Everitt; David Goulding; Christine Hale; Robert E W Hancock; Mark Lucas; Rebecca E McIntyre; Lynda Mottram; Gordon Dougan
The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation.
Blood 2012;119(6):1370-9.
2012: Anastasia Nijnik; Jelena Pistolic; Niall C J Filewod; Robert E W Hancock
Signaling pathways mediating chemokine induction in keratinocytes by cathelicidin LL-37 and flagellin.
Journal of innate immunity 2012;4(4):377-86.
2011: Gimano D Amatngalim; Pieter S Hiemstra; Anastasia Nijnik; Robert E W Hancock
Cathelicidin peptide LL-37 modulates TREM-1 expression and inflammatory responses to microbial compounds.
Inflammation 2011;34(5):412-25.
2011: Alexander Diehl; Alison Deckhut Augustine; Judith A Blake; Lindsay G Cowell; Elizabeth S Gold; Timothy A Gondré-Lewis; Anna Maria Masci; Terrence F Meehan; Penelope A Morel; Anastasia Nijnik; Bjoern Peters; Bali Pulendran; Richard H Scheuermann; Q Alison Yao; Martin S Zand; Christopher J Mungall
Hematopoietic cell types: prototype for a revised cell ontology.
Journal of biomedical informatics 2011;44(1):75-9.
2010: Anastasia Nijnik; Laurence Madera; Shuhua Ma; Matthew Waldbrook; Melissa R Elliott; Donna M Easton; Matthew Mayer; Sarah C Mullaly; Jason Kindrachuk; Håvard Jenssen; Robert E W Hancock
Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(5):2539-50.
2009: Anastasia Nijnik; Jelena Pistolic; Aaron Wyatt; Sheena Tam; Robert E W Hancock
Human cathelicidin peptide LL-37 modulates the effects of IFN-gamma on APCs.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(9):5788-98.
2009: Donna M Easton; Anastasia Nijnik; Matthew Mayer; Robert E W Hancock
Potential of immunomodulatory host defense peptides as novel anti-infectives.
Trends in biotechnology 2009;27(10):582-90.
2009: Neeloffer Mookherjee; Dustin N D Lippert; Pamela Hamill; Reza Falsafi; Anastasia Nijnik; Jason Kindrachuk; Jelena Pistolic; Jennifer Gardy; Pegah Miri; Misbah Naseer; Leonard J Foster; Robert E W Hancock
Intracellular receptor for human host defense peptide LL-37 in monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2688-96.
2009: Jason Kindrachuk; Håvard Jenssen; Melissa Elliott; Rebecca Townsend; Anastasia Nijnik; Song F Lee; Volker Gerdts; Lorne A Babiuk; Scott A Halperin; Robert E W Hancock
A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity.
Vaccine 2009;27(34):4662-71.
2009: Anastasia Nijnik; Sara Dawson; Tanya L Crockford; Lisa Woodbine; Supawan Visetnoi; Sophia Bennett; Margaret Jones; Gareth D H Turner; Penny A Jeggo; Christopher C Goodnow; Richard J Cornall
Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome.
The Journal of clinical investigation 2009;119(6):1696-705.
2009: Anastasia Nijnik; Rew Hancock
Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections.
Emerging health threats journal 2009;2():e1.
2009: Anastasia Nijnik; Robert E W Hancock
The roles of cathelicidin LL-37 in immune defences and novel clinical applications.
Current opinion in hematology 2009;16(1):41-7.
2007: Anastasia Nijnik; Lisa Woodbine; Caterina Marchetti; Sara Dawson; Teresa Lambe; Cong Liu; Neil P Rodrigues; Tanya L Crockford; Erik Cabuy; Alessandro Vindigni; Tariq Enver; John I Bell; Predrag Slijepcevic; Christopher C Goodnow; Penny A Jeggo; Richard J Cornall
DNA repair is limiting for haematopoietic stem cells during ageing.
Nature 2007;447(7145):686-90.
2007: Helen Ferry; Paul Potter; Tanya L Crockford; Anastasia Nijnik; Michael R Ehrenstein; Mark J Walport; Marina Botto; Richard J Cornall
Increased positive selection of B1 cells and reduced B cell tolerance to intracellular antigens in c1q-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):2916-22.
2006: Anastasia Nijnik; Helen Ferry; Graham Lewis; Eleni Rapsomaniki; Janson C H Leung; Angelika Daser; Teresa Lambe; Christopher C Goodnow; Richard J Cornall
Spontaneous B cell hyperactivity in autoimmune-prone MRL mice.
International immunology 2006;18(7):1127-37.
2006: Neil Hanchard; Mahamadou DIAKITE; Oliver Koch; Brendan J Keating; Margaret Pinder; Muminatou Jallow; Fatoumatta Sisay-Joof; Anastasia Nijnik; Jonathan Wilson; Irina A Udalova; Dominic Kwiatkowski; Kirk Rockett
Implications of inter-population linkage disequilibrium patterns on the approach to a disease association study in the human MHC class III.
Immunogenetics 2006;58(5-6):465-70.
2006: Helen Ferry; Janson C H Leung; Graham Lewis; Anastasia Nijnik; Karlee Silver; Teresa Lambe; Richard J Cornall
B-cell tolerance.
Transplantation 2006;81(3):308-15.
2006: Neil Hanchard; Kirk Rockett; Irina A Udalova; Jonathan Wilson; Brendan J Keating; Oliver Koch; Anastasia Nijnik; Mahamadou DIAKITE; M Herbert; Dominic Kwiatkowski
An investigation of transmission ratio distortion in the central region of the human MHC.
Genes and immunity 2006;7(1):51-8.
2003: Anastasia Nijnik; Richard Mott; Dominic P Kwiatkowski; Irina A Udalova
Comparing the fine specificity of DNA binding by NF-kappaB p50 and p52 using principal coordinates analysis.
Nucleic acids research 2003;31(5):1497-501.