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Wolfgang Bernhard

Research Profile

Chemicals & Drugs

Phenomena

Surface Tension

Anatomy

Living Beings

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High Pressure Liquid Chromatography

Disorders

Cystic Fibrosis

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Publications

TOP 3
Wolfgang Bernhard; Anna Full; Christoph Maas; Christian F Poets; Jörg Arand; Axel R Franz
Choline supply of preterm infants: assessment of dietary intake and pathophysiological considerations.
Jens Gesche; Matthias Griese; Roland Koslowski; Florian M Ohler; Christian F Poets; Christopher J Pynn; Heinz Fehrenbach; Wolfgang Bernhard
rhKGF stimulates lung surfactant production in neonatal rats in vivo.
Wolfgang Bernhard; Christian Gille; Christopher J Pynn; Marco Raith; Erwin Schleicher; Guido Stichtenoth; Dieter Stoll; Christian F Poets
Increased palmitoyl-myristoyl-phosphatidylcholine in neonatal rat surfactant is lung specific and correlates with oral myristic acid supply.

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All Publications

2013: Wolfgang Bernhard; Anna Full; Christoph Maas; Christian F Poets; Jörg Arand; Axel R Franz
Choline supply of preterm infants: assessment of dietary intake and pathophysiological considerations.
European journal of nutrition 2013;52(3):1269-78.
2011: Jens Gesche; Matthias Griese; Roland Koslowski; Florian M Ohler; Christian F Poets; Christopher J Pynn; Heinz Fehrenbach; Wolfgang Bernhard
rhKGF stimulates lung surfactant production in neonatal rats in vivo.
Pediatric pulmonology 2011;46(9):882-95.
2011: Wolfgang Bernhard; Christian Gille; Christopher J Pynn; Marco Raith; Erwin Schleicher; Guido Stichtenoth; Dieter Stoll; Christian F Poets
Increased palmitoyl-myristoyl-phosphatidylcholine in neonatal rat surfactant is lung specific and correlates with oral myristic acid supply.
Journal of applied physiology (Bethesda, Md. : 1985) 2011;111(2):449-57.
2011: Christopher J Pynn; Neil G Henderson; Howard Clark; Grielof Koster; Wolfgang Bernhard; Anthony D Postle
Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo.
Journal of lipid research 2011;52(2):399-407.
2010: Christopher J Pynn; M Victoria Picardi; Tim Nicholson; Dorothee Wistuba; Christian F Poets; Erwin Schleicher; Jesus Perez-Gil; Wolfgang Bernhard
Myristate is selectively incorporated into surfactant and decreases dipalmitoylphosphatidylcholine without functional impairment.
American journal of physiology. Regulatory, integrative and comparative physiology 2010;299(5):R1306-16.
2009: Wolfgang Bernhard; Christopher J Pynn
Therapeutic lung surfactants as carriers for other therapeutics--a matter of vision, courage and determination.
Pediatric pulmonology 2009;44(12):1157-8.
2007: Wolfgang Bernhard; Andreas Schmiedl; Grielof Koster; Sandra Orgeig; Christa Acevedo; Christian F Poets; Anthony D Postle
Developmental changes in rat surfactant lipidomics in the context of species variability.
Pediatric pulmonology 2007;42(9):794-804.
2007: Andreas Schmiedl; Gertrud Vieten; Christian Mühlfeld; Wolfgang Bernhard
Distribution of intracellular and secreted surfactant during postnatal rat lung development.
Pediatric pulmonology 2007;42(6):548-62.
2007: Christian Gille; Bärbel Spring; Wolfgang Bernhard; Caroline Gebhard; Denise Basile; Kirsten Lauber; Christian F Poets; Thorsten W Orlikowsky
Differential effect of surfactant and its saturated phosphatidylcholines on human blood macrophages.
Journal of lipid research 2007;48(2):307-17.
2006: Heike Dombrowsky; Thomas Tschernig; Gertrud Vieten; Gunnar A Rau; Florian Ohler; Christa Acevedo; Clemens Behrens; Christian F Poets; Horst von der Hardt; Wolfgang Bernhard
Molecular and functional changes of pulmonary surfactant in response to hyperoxia.
Pediatric pulmonology 2006;41(11):1025-39.
2006: Anthony D Postle; Linda W Gonzales; Wolfgang Bernhard; Graeme Clark; Marye H Godinez; Rodolfo I Godinez; Philip L Ballard
Lipidomics of cellular and secreted phospholipids from differentiated human fetal type II alveolar epithelial cells.
Journal of lipid research 2006;47(6):1322-31.
2005: Carol J Lang; Anthony D Postle; Sandra Orgeig; Fred Possmayer; Wolfgang Bernhard; Amiya Kumar Panda; Klaus D Jürgens; William K Milsom; Kaushik Nag; Christopher B Daniels
Dipalmitoylphosphatidylcholine is not the major surfactant phospholipid species in all mammals.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;289(5):R1426-39.
2004: Wolfgang Bernhard; Christopher J Pynn; Andreas Jaworski; Gunnar A Rau; Jens Hohlfeld; Joachim Freihorst; Christian F Poets; Dieter Stoll; Anthony D Postle
Mass spectrometric analysis of surfactant metabolism in human volunteers using deuteriated choline.
American journal of respiratory and critical care medicine 2004;170(1):54-8.
2004: Roger G Spragg; Paul J Ponganis; James J Marsh; Gunnar A Rau; Wolfgang Bernhard
Surfactant from diving aquatic mammals.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;96(5):1626-32.
2004: Gunnar A Rau; Gertrud Vieten; Jack J Haitsma; Joachim Freihorst; Christian F Poets; Benno M Ure; Wolfgang Bernhard
Surfactant in newborn compared with adolescent pigs: adaptation to neonatal respiration.
American journal of respiratory cell and molecular biology 2004;30(5):694-701.
2004: Wolfgang Bernhard; Patricia L Haslam; Joanna Floros
From birds to humans: new concepts on airways relative to alveolar surfactant.
American journal of respiratory cell and molecular biology 2004;30(1):6-11.
2003: Gunnar A Rau; Heike Dombrowsky; Andreas Gebert; Hubert Thole; Horst von der Hardt; Joachim Freihorst; Wolfgang Bernhard
Phosphatidylcholine metabolism of rat trachea in relation to lung parenchyma and surfactant.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;95(3):1145-52.
2003: Heike Dombrowsky; Graeme Clark; Gunnar A Rau; Wolfgang Bernhard; Anthony D Postle
Molecular species compositions of lung and pancreas phospholipids in the cftr(tm1HGU/tm1HGU) cystic fibrosis mouse.
Pediatric research 2003;53(3):447-54.
2002: Ann Mander; Simon Langton Hewer; Wolfgang Bernhard; John O Warner; Anthony D Postle
Altered phospholipid composition and aggregate structure of lung surfactant is associated with impaired lung function in young children with respiratory infections.
American journal of respiratory cell and molecular biology 2002;27(6):714-21.
2002: M Larbig; Silke Jansen; Martina Dorsch; Wolfgang Bernhard; Bernd Bellmann; J R Dorin; D J Porteous; Horst von der Hardt; I Steinmetz; Hans J Hedrich; B Tuemmler; Thomas Tschernig
Residual cftr expression varies with age in cftr(tm1Hgu) cystic fibrosis mice: impact on morphology and physiology.
Pathobiology : journal of immunopathology, molecular and cellular biology 2002;70(2):89-97.
2001: Wolfgang Bernhard; S Hoffmann; Heike Dombrowsky; Gunnar A Rau; A Kamlage; Martin Kappler; Jack J Haitsma; Joachim Freihorst; Horst von der Hardt; Christian F Poets
Phosphatidylcholine molecular species in lung surfactant: composition in relation to respiratory rate and lung development.
American journal of respiratory cell and molecular biology 2001;25(6):725-31.
2001: Wolfgang Bernhard; Andreas Gebert; Gertrud Vieten; Gunnar A Rau; Jens Hohlfeld; Anthony D Postle; Joachim Freihorst
Pulmonary surfactant in birds: coping with surface tension in a tubular lung.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(1):R327-37.
2001: Wolfgang Bernhard; A Bertling; Heike Dombrowsky; Gertrud Vieten; Gunnar A Rau; Horst von der Hardt; Joachim Freihorst
Metabolism of surfactant phosphatidylcholine molecular species in cftr(tm1HGU/tm1HGU) mice compared to MF-1 mice.
Experimental lung research 2001;27(4):349-66.
2001: Wolfgang Bernhard; Anthony D Postle; Gunnar A Rau; Joachim Freihorst
Pulmonary and gastric surfactants. A comparison of the effect of surface requirements on function and phospholipid composition.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2001;129(1):173-82.
2000: Wolfgang Bernhard; J Mottaghian; Andreas Gebert; Gunnar A Rau; Horst von der Hardt; Christian F Poets
Commercial versus native surfactants. Surface activity, molecular components, and the effect of calcium.
American journal of respiratory and critical care medicine 2000;162(4 Pt 1):1524-33.
1998: N Pallua; K Warbanow; E M Noah; Thomas Lange; Christian F Poets; Wolfgang Bernhard; A Berger
Intrabronchial surfactant application in cases of inhalation injury: first results from patients with severe burns and ARDS.
Burns : journal of the International Society for Burn Injuries 1998;24(3):197-206.
1997: Wolfgang Bernhard; J Y Wang; Thomas Tschernig; Burkhard Tümmler; Hans J Hedrich; Horst von der Hardt
Lung surfactant in a cystic fibrosis animal model: increased alveolar phospholipid pool size without altered composition and surface tension function in cftrm1HGU/m1HGU mice.
Thorax 1997;52(8):723-30.
1997: Wolfgang Bernhard; H P Haagsman; Thomas Tschernig; Christian F Poets; Anthony D Postle; Martin van Eijk; Horst von der Hardt
Conductive airway surfactant: surface-tension function, biochemical composition, and possible alveolar origin.
American journal of respiratory cell and molecular biology 1997;17(1):41-50.
1997: Christian F Poets; A Arning; Wolfgang Bernhard; Christa Acevedo; Horst von der Hardt
Active surfactant in pharyngeal aspirates of term neonates: lipid biochemistry and surface tension function.
European journal of clinical investigation 1997;27(4):293-8.
1996: K Raymondos; I Martin-Carrera; Wolfgang Bernhard; Christian F Poets; H von der Hardt
A method for the isolation and preparation of surfactant from tracheobronchial aspirates in infants and children for quantitative and pulsating bubble analysis.
European journal of clinical investigation 1996;26(11):983-8.
1996: Wolfgang Bernhard; H Schulte; M Piller; K F Sewing
Synthesis and release of phosphatidylcholine by isolated porcine gastric mucous cells in primary culture.
European journal of clinical investigation 1996;26(9):797-802.
1996: Wolfgang Bernhard; A D Postle; M Linck; KF Sewing
Rat gastric hydrophobic barrier: modulation of phosphatidylcholine molecular species by dietary lipids.
Lipids 1996;31(5):507-11.
1995: Wolfgang Bernhard; A D Postle; M Linck; KF Sewing
Composition of phospholipid classes and phosphatidylcholine molecular species of gastric mucosa and mucus.
Biochimica et biophysica acta 1995;1255(2):99-104.
1994: Wolfgang Bernhard; M Linck; H Creutzburg; A D Postle; A Arning; I Martin-Carrera; KF Sewing
High-performance liquid chromatographic analysis of phospholipids from different sources with combined fluorescence and ultraviolet detection.
Analytical biochemistry 1994;220(1):172-80.
1994: Wolfgang Bernhard; B Müller; P Von Wichert
beta-Adrenergic priming of rats in vivo modulates the effect of beta-agonist in vitro on surfactant phospholipid metabolism of isolated lungs.
European journal of clinical investigation 1994;24(6):393-9.
1994: Wolfgang Bernhard; M Linck; M Beinborn; P Schünemann; KF Sewing
Phospholipid synthesis in isolated porcine gastric mucous cells.
Pharmacology 1994;48(3):176-86.
1993: Reiner Mengel; Wolfgang Bernhard; P Barth; Peter von Wichert; Bernd Müller
Impaired regulation of surfactant phospholipid metabolism in the isolated rat lung after nitrogen dioxide inhalation.
Toxicology and applied pharmacology 1993;120(2):216-23.
1993: A Gbarah; David Mirelman; P J Sansonetti; R Verdon; Wolfgang Bernhard; N Sharon
Shigella flexneri transformants expressing type 1 (mannose-specific) fimbriae bind to, activate, and are killed by phagocytic cells.
Infection and immunity 1993;61(5):1687-93.
1992: Wolfgang Bernhard; A Gbarah; N Sharon
Lectinophagocytosis of type 1 fimbriated (mannose-specific) Escherichia coli in the mouse peritoneum.
Journal of leukocyte biology 1992;52(3):343-8.