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Ijaz Qureshi

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Marc Girardin; Philippe Goyette; Emile Levy; Ijaz Qureshi; John Rioux; Alain Bitton; Patrick Charlebois; Serge Dionne; Ihsan Elimrani; Ernest G Seidman
Expression and functional analysis of intestinal organic cation/L-carnitine transporter (OCTN) in Crohn's disease.
Karim Lahjouji; Ihsan Elimrani; Julie Lafond; Line Leduc; Ijaz Qureshi; Grant A Mitchell
L-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2.
Ihsan Elimrani; Karim Lahjouji; Ernest Seidman; Marie-Josee Roy; Grant A Mitchell; Ijaz Qureshi
Expression and localization of organic cation/carnitine transporter OCTN2 in Caco-2 cells.

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2012: Marc Girardin; Philippe Goyette; Emile Levy; Ijaz Qureshi; John Rioux; Alain Bitton; Patrick Charlebois; Serge Dionne; Ihsan Elimrani; Ernest G Seidman
Expression and functional analysis of intestinal organic cation/L-carnitine transporter (OCTN) in Crohn's disease.
Journal of Crohn's & colitis 2012;6(2):189-97.
2004: Karim Lahjouji; Ihsan Elimrani; Julie Lafond; Line Leduc; Ijaz Qureshi; Grant A Mitchell
L-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2.
American journal of physiology. Cell physiology 2004;287(2):C263-9.
2003: Ihsan Elimrani; Karim Lahjouji; Ernest Seidman; Marie-Josee Roy; Grant A Mitchell; Ijaz Qureshi
Expression and localization of organic cation/carnitine transporter OCTN2 in Caco-2 cells.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(5):G863-71.
2002: Karim Lahjouji; Ihsan Elimrani; Jie Wu; Grant A Mitchell; Ijaz Qureshi
A heterozygote phenotype is present in the jvs +/- mutant mouse livers.
Molecular genetics and metabolism 2002;76(1):76-80.
2002: Karim Lahjouji; Christiane Malo; Grant A Mitchell; Ijaz Qureshi
L-Carnitine transport in mouse renal and intestinal brush-border and basolateral membrane vesicles.
Biochimica et biophysica acta 2002;1558(1):82-93.
2001: Karim Lahjouji; Grant A Mitchell; Ijaz Qureshi
Carnitine transport by organic cation transporters and systemic carnitine deficiency.
Molecular genetics and metabolism 2001;73(4):287-97.
2001: R Benzerrouk; Ijaz Qureshi
Hepatic mitochondrial proteins in congenitally hyperammonemic spf mice: effect of acetyl-L-carnitine.
Bioscience, biotechnology, and biochemistry 2001;65(3):495-500.
2000: Rudi D'Hooge; Bart Marescau; Ijaz Qureshi; Peter Paul De Deyn
Impaired cognitive performance in ornithine transcarbamylase-deficient mice on arginine-free diet.
Brain research 2000;876(1-2):1-9.
1999: K V Rama Rao; Ijaz Qureshi
Reduction in the MK-801 binding sites of the NMDA sub-type of glutamate receptor in a mouse model of congenital hyperammonemia: prevention by acetyl-L-carnitine.
Neuropharmacology 1999;38(3):383-94.
1998: YR Mawal; KV Rama Rao; Ijaz Qureshi
Restoration of hepatic cytochrome c oxidase activity and expression with acetyl-L-carnitine treatment in spf mice with an ornithine transcarbamylase deficiency.
Biochemical pharmacology 1998;55(11):1853-60.
1998: K Qureshi; K V Rama Rao; Ijaz Qureshi
Differential inhibition by hyperammonemia of the electron transport chain enzymes in synaptosomes and non-synaptic mitochondria in ornithine transcarbamylase-deficient spf-mice: restoration by acetyl-L-carnitine.
Neurochemical research 1998;23(6):855-61.
1997: François Proulx; J Lacroix; Ijaz Qureshi; D Nadeau; M Gauthier; M Lambert
Acquired carnitine abnormalities in critically ill children.
European journal of pediatrics 1997;156(11):864-9.
1997: A Skarpetas; YR Mawal; Ijaz Qureshi
Developmental study of hepatic glutamine synthetase in a mouse model of congenital hyperammonemia.
Biochemistry and molecular biology international 1997;43(1):133-9.
1997: YR Mawal; K Paradis; Ijaz Qureshi
Developmental profile of mitochondrial glycine N-acyltransferase in human liver.
The Journal of pediatrics 1997;130(6):1003-7.
1997: K V Rama Rao; Ijaz Qureshi
Decompensation of hepatic and cerebral acyl-CoA metabolism in BALB/cByJ mice by chronic riboflavin deficiency: restoration by acetyl-L-carnitine.
Canadian journal of physiology and pharmacology 1997;75(5):423-30.
1997: K V Rama Rao; YR Mawal; Ijaz Qureshi
Progressive decrease of cerebral cytochrome C oxidase activity in sparse-fur mice: role of acetyl-L-carnitine in restoring the ammonia-induced cerebral energy depletion.
Neuroscience letters 1997;224(2):83-6.
1997: Ijaz Qureshi; K V Rao
Sparse-fur (spf) mouse as a model of hyperammonemia: alterations in the neurotransmitter systems.
Advances in experimental medicine and biology 1997;420():143-58.
1996: L Ratnakumari; Ijaz Qureshi; Roger F Butterworth; B Marescau; P P De Deyn
Arginine-related guanidino compounds and nitric oxide synthase in the brain of ornithine transcarbamylase deficient spf mutant mouse: effect of metabolic arginine deficiency.
Neuroscience letters 1996;215(3):153-6.
1996: L Ratnakumari; Ijaz Qureshi; Roger F Butterworth
Central muscarinic cholinergic M1 and M2 receptor changes in congenital ornithine transcarbamylase deficiency.
Pediatric research 1996;40(1):25-8.
1996: Juan Carlos Feoli-Fonseca; Marie Lambert; G Mitchell; SB Melançon; Louis Dallaire; D S Millington; Ijaz Qureshi
Chronic sodium benzoate therapy in children with inborn errors of urea synthesis: effect on carnitine metabolism and ammonia nitrogen removal.
Biochemical and molecular medicine 1996;57(1):31-6.
1995: L Ratnakumari; Robert Audet; Ijaz Qureshi; Roger F Butterworth
Na+,K(+)-ATPase activities are increased in brain in both congenital and acquired hyperammonemic syndromes.
Neuroscience letters 1995;197(2):89-92.
1995: L Ratnakumari; Ijaz Qureshi; Roger F Butterworth
Loss of [3H]MK801 binding sites in brain in congenital ornithine transcarbamylase deficiency.
Metabolic brain disease 1995;10(3):249-55.
1995: T Uchino; Selma E Snyderman; M Lambert; Ijaz Qureshi; S K Shapira; Claude Sansaricq; L M Smit; C Jakobs; I Matsuda
Molecular basis of phenotypic variation in patients with argininemia.
Human genetics 1995;96(3):255-60.
1995: L Ratnakumari; Ijaz Qureshi; Dusica Maysinger; Roger F Butterworth
Developmental deficiency of the cholinergic system in congenitally hyperammonemic spf mice: effect of acetyl-L-carnitine.
The Journal of pharmacology and experimental therapeutics 1995;274(1):437-43.
1995: A Michalak; Ijaz Qureshi
Free and esterified coenzyme A in the liver and muscles of chronically hyperammonemic mice treated with sodium benzoate.
Biochemical and molecular medicine 1995;54(2):96-104.
1995: S Vasudevan; Ijaz Qureshi; M Lambert; Prema M Rao; Srinivasan Rajalakshmi; Dittakavi S R Sarma
Nucleotide pool imbalances in the livers of patients with urea cycle disorders associated with increased levels of orotic aciduria.
Biochemistry and molecular biology international 1995;35(3):685-90.
1995: A Michalak; Ijaz Qureshi
Tissue acylcarnitine and acyl-coenzyme A profiles in chronically hyperammonemic mice treated with sodium benzoate and supplementary L-carnitine.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1995;49(7-8):350-7.
1995: Peter Paul De Deyn; P Robitaille; M Vanasse; Ijaz Qureshi; Bart Marescau
Serum guanidino compound levels in uremic pediatric patients treated with hemodialysis or continuous cycle peritoneal dialysis. Correlations between nerve conduction velocities and altered guanidino compound concentrations.
Nephron 1995;69(4):411-7.
1994: YR Mawal; Ijaz Qureshi
Purification to homogeneity of mitochondrial acyl coa:glycine n-acyltransferase from human liver.
Biochemical and biophysical research communications 1994;205(2):1373-9.
1994: YR Mawal; Ijaz Qureshi
An immunodetection method for the quantitation of human acyl CoA:glycine N-acyltransferase in biological samples.
Biochemistry and molecular biology international 1994;34(3):595-601.
1994: L Ratnakumari; Ijaz Qureshi; Roger F Butterworth
Evidence for cholinergic neuronal loss in brain in congenital ornithine transcarbamylase deficiency.
Neuroscience letters 1994;178(1):63-5.
1994: V L Rao; Ijaz Qureshi; Roger F Butterworth
Activities of monoamine oxidase-A and -B are altered in the brains of congenitally hyperammonemic sparse-fur (spf) mice.
Neuroscience letters 1994;170(1):27-30.
1994: L Ratnakumari; Ijaz Qureshi; Roger F Butterworth
Regional amino acid neurotransmitter changes in brains of spf/Y mice with congenital ornithine transcarbamylase deficiency.
Metabolic brain disease 1994;9(1):43-51.
1993: V L Rao; Ijaz Qureshi; Roger F Butterworth
Increased densities of binding sites for the peripheral-type benzodiazepine receptor ligand [3H]PK 11195 in congenital ornithine transcarbamylase-deficient sparse fur mouse.
Pediatric research 1993;34(6):777-80.
1993: Ijaz Qureshi; L Ratnakumari; A Michalak; Robert Giguère; D Cyr; Roger F Butterworth
A profile of cerebral and hepatic carnitine, ammonia, and energy metabolism in a model of organic aciduria: BALB/cByJ mouse with short-chain acyl-CoA dehydrogenase deficiency.
Biochemical medicine and metabolic biology 1993;50(2):145-58.
1993: J Nelson; Ijaz Qureshi; S Vasudevan; D S Sarma
The effects of various inhibitors on the regulation of orotic acid excretion in sparse-fur mutant mice (spf/Y) deficient in ornithine transcarbamylase.
Chemico-biological interactions 1993;89(1):35-47.
1993: G C Tremblay; Ijaz Qureshi
The biochemistry and toxicology of benzoic acid metabolism and its relationship to the elimination of waste nitrogen.
Pharmacology & therapeutics 1993;60(1):63-90.
1993: L Ratnakumari; Ijaz Qureshi; Roger F Butterworth
Effect of L-carnitine on cerebral and hepatic energy metabolites in congenitally hyperammonemic sparse-fur mice and its role during benzoate therapy.
Metabolism: clinical and experimental 1993;42(8):1039-46.
1993: A Michalak; Ijaz Qureshi
[Carnitine levels in muscle in mice with hyperammonemia: effect of treatment with sodium benzoate].
Canadian journal of physiology and pharmacology 1993;71(7):439-46.
1993: J Nelson; Ijaz Qureshi; V S Ghole; D R Deshmukh
Regulation of orotic acid biosynthesis and excretion induced by oral glutamine administration in mice.
Biochemical medicine and metabolic biology 1993;49(3):338-50.
1993: Ijaz Qureshi; D Leblanc; D Cyr; Robert Giguère; G Mitchell
Breeding experiments to combine the X-linked sparse-fur (spf) mutation with the autosomal recessive BALB/cByJ strain: testing the biochemical phenotype of double-mutant mice as a model for ammonia: fatty acyl CoA synergism.
Biochemical and biophysical research communications 1993;191(2):744-9.
1993: J Christodoulou; Ijaz Qureshi; R R McInnes; Joe T R Clarke
Ornithine transcarbamylase deficiency presenting with strokelike episodes.
The Journal of pediatrics 1993;122(3):423-5.
1993: L Ratnakumari; Ijaz Qureshi; Roger F Butterworth
Effect of sodium benzoate on cerebral and hepatic energy metabolites in spf mice with congenital hyperammonemia.
Biochemical pharmacology 1993;45(1):137-46.
1993: A Michalak; Ijaz Qureshi
[Profile of hepatic and muscular acylcarnitines in chronically hyperammonemic mice after an acute treatment with sodium benzoate: dose-response study].
Annales de biologie clinique 1993;51(10-11):879-85.
1992: L Smith; M A Lambert; Pierre Brochu; G Jasmin; Ijaz Qureshi; E G Seidman
Hyperornithinemia, hyperammonemia, homocitrullinuria (HHH) syndrome: presentation as acute liver disease with coagulopathy.
Journal of pediatric gastroenterology and nutrition 1992;15(4):431-6.
1992: Bart Marescau; Peter Paul De Deyn; Ijaz Qureshi; Marc E De Broe; I Antonozzi; S D Cederbaum; R Cerone; N Chamoles; R Gatti; S S Kang
The pathobiochemistry of uremia and hyperargininemia further demonstrates a metabolic relationship between urea and guanidinosuccinic acid.
Metabolism: clinical and experimental 1992;41(9):1021-4.
1992: S Vasudevan; Ijaz Qureshi; L Mores; Prema M Rao; Srinivasan Rajalakshmi; Dittakavi S R Sarma
Abnormal hepatic nucleotide pools in sparse fur (spf) mutant mice deficient in ornithine transcarbamylase.
Biochemical medicine and metabolic biology 1992;47(3):274-8.
1992: Bart Marescau; D R Deshmukh; M Kockx; I Possemiers; Ijaz Qureshi; P Wiechert; Peter Paul De Deyn
Guanidino compounds in serum, urine, liver, kidney, and brain of man and some ureotelic animals.
Metabolism: clinical and experimental 1992;41(5):526-32.
1992: L Ratnakumari; Ijaz Qureshi; Roger F Butterworth
Effects of congenital hyperammonemia on the cerebral and hepatic levels of the intermediates of energy metabolism in spf mice.
Biochemical and biophysical research communications 1992;184(2):746-51.
1992: J Nelson; Ijaz Qureshi; S Vasudevan
[Mechanism of the effect of serine and threonine on ammoniagenesis and biosynthesis of orotate in the mouse].
Clinical and investigative medicine. Médecine clinique et experimentale 1992;15(2):113-21.
1992: Michael B Robinson; N J Anegawa; E Gorry; Ijaz Qureshi; J T Coyle; I Lucki; M L Batshaw
Brain serotonin2 and serotonin1A receptors are altered in the congenitally hyperammonemic sparse fur mouse.
Journal of neurochemistry 1992;58(3):1016-22.
1992: A Ali; Ijaz Qureshi
Benzoyl-CoA ligase activity in the liver and kidney cortex of weanling guinea pigs treated with various inducers: relationship with hippurate synthesis and carnitine levels.
Developmental pharmacology and therapeutics 1992;18(1-2):55-64.
1991: M A Lambert; B Marescau; Michel Desjardins; M Laberge; J L Dhondt; Louis Dallaire; P P De Deyn; Ijaz Qureshi
Hyperargininemia: intellectual and motor improvement related to changes in biochemical data.
The Journal of pediatrics 1991;118(3):420-4.
1990: A Michalak; M A Lambert; Louis Dallaire; S B Melançon; R Laframboise; Bernard Lemieux; Ijaz Qureshi
[Hypocarnitinemia in patients affected by a primary defect of ammonia metabolism treated with sodium benzoate].
Diabète & métabolisme 1990;16(3):226-33.
1990: Adriana Michalak; Ijaz Qureshi
Plasma and urinary levels of carnitine in different experimental models of hyperammonemia and the effect of sodium benzoate treatment.
Biochemical medicine and metabolic biology 1990;43(2):163-74.
1990: Bart Marescau; Peter Paul De Deyn; A Lowenthal; Ijaz Qureshi; I Antonozzi; C Bachmann; S D Cederbaum; R Cerone; N Chamoles; J P Colombo
Guanidino compound analysis as a complementary diagnostic parameter for hyperargininemia: follow-up of guanidino compound levels during therapy.
Pediatric research 1990;27(3):297-303.
1989: Ijaz Qureshi; P Clermont; J Letarte
The importance of glyoxylate and other glycine precursors in the hepatic and renal conjugation of benzoate in normal and hyperammonemic mice.
Canadian journal of physiology and pharmacology 1989;67(11):1426-30.
1989: Ijaz Qureshi; S Lebel; J Letarte
Development and inducibility of the hepatic and renal hippurate-synthesizing system in sparse-fur (spf) mutant mice with ornithine transcarbamylase deficiency.
Biochemistry international 1989;19(3):657-66.
1988: H M Heick; R G Peterson; M Dalpe-Scott; Ijaz Qureshi
Insect repellent, N,N-diethyl-m-toluamide, effect on ammonia metabolism.
Pediatrics 1988;82(3):373-6.
1988: Mark L Batshaw; S L Hyman; Joseph T Coyle; Michael B Robinson; Ijaz Qureshi; E D Mellits; SA Quaskey
Effect of sodium benzoate and sodium phenylacetate on brain serotonin turnover in the ornithine transcarbamylase-deficient sparse-fur mouse.
Pediatric research 1988;23(4):368-74.
1986: Ijaz Qureshi; J Letarte; S Lebel; R Ouellet
[Variability of enzyme activity and urinary orotic acid in ornithine transcarbamylase deficient spf/+ heterozygotic mice].
Diabète & métabolisme 1986;12(5):250-5.
1986: Ijaz Qureshi; J Letarte; B Tuchweber; I Yousef; S R Qureshi
The role of hepatic ornithine transcarbamylase deficiency in the orotic aciduria of pregnant mice.
European journal of obstetrics, gynecology, and reproductive biology 1986;22(3):183-91.
1986: C Malo; Ijaz Qureshi; J Letarte
Postnatal maturation of enterocytes in sparse-fur mutant mice.
The American journal of physiology 1986;250(2 Pt 1):G177-84.
1986: Ijaz Qureshi; J Letarte; R Ouellet; B Lemieux; L Cathelineau
Kinetic abnormalities of carbamyl phosphate synthetase-I in a case of congenital hyperammonaemia.
Journal of inherited metabolic disease 1986;9(3):253-60.
1985: Ijaz Qureshi; J Letarte; B Tuchweber; I Yousef; S R Qureshi
Hepatotoxicity of sodium valproate in ornithine transcarbamylase-deficient mice.
Toxicology letters 1985;25(3):297-306.
1985: J Letarte; Ijaz Qureshi; R Ouellet; M Godard
Chronic benzoate therapy in a boy with partial ornithine transcarbamylase deficiency.
The Journal of pediatrics 1985;106(5):794-7.
1985: Bart Marescau; Ijaz Qureshi; P De Deyn; J Letarte; R Ryba; A Lowenthal
Guanidino compounds in plasma, urine and cerebrospinal fluid of hyperargininemic patients during therapy.
Clinica chimica acta; international journal of clinical chemistry 1985;146(1):21-7.
1985: Ijaz Qureshi; J Letarte; R Ouellet
Expression of ornithine transcarbamylase deficiency in the small intestine and colon of sparse-fur mutant mice.
Journal of pediatric gastroenterology and nutrition 1985;4(1):118-24.
1984: G Call; A R Seay; R Sherry; Ijaz Qureshi
Clinical features of carbamyl phosphate synthetase-I deficiency in an adult.
Annals of neurology 1984;16(1):90-3.
1984: Ijaz Qureshi; J Letarte; R Ouellet; M L Batshaw; S Brusilow
Treatment of hyperargininemia with sodium benzoate and arginine-restricted diet.
The Journal of pediatrics 1984;104(3):473-6.
1983: Ijaz Qureshi; J Letarte; R Ouellet; J Larochelle; B Lemieux
A new French-Canadian family affected by hyperargininaemia.
Journal of inherited metabolic disease 1983;6(4):179-82.
1982: Ijaz Qureshi; J Letarte; R Ouellet
Activity of orotate metabolizing enzyme complex and various urea-cycle enzymes in mutant mice with ornithine transcarbamylase deficiency.
Experientia 1982;38(3):308-9.
1982: Ijaz Qureshi; J Letarte; R Ouellet
Spontaneous animal models of ornithine transcarbamylase deficiency: studies on serum and urinary nitrogenous metabolites.
Advances in experimental medicine and biology 1982;153():173-83.
1981: Ijaz Qureshi; J Letarte; R Ouellet; M Lelièvre; C Laberge
Ammonia metabolism in a family affected by hyperargininemia.
Diabète & métabolisme 1981;7(1):5-11.
1980: J C Le Guennec; Ijaz Qureshi; Harry Bard; J Y Siriez; J Letarte
Transient hyperammonemia in an early preterm infant.
The Journal of pediatrics 1980;96(3 Pt 1):470-2.
1979: Ijaz Qureshi; J Letarte; R Ouellet
Ornithine transcarbamylase deficiency in mutant mice I. Studies on the characterization of enzyme defect and suitability as animal model of human disease.
Pediatric research 1979;13(7):807-11.
1978: Ijaz Qureshi; J Letarte; R Quellet
Study of enzyme defect in a case of ornithine transcarbamylase deficiency.
Diabète & métabolisme 1978;4(4):239-41.
1978: Ijaz Qureshi; J Letarte; R Ouellet; B Lemieux
Enzymologic and metabolic studies in two families affected by argininosuccinic aciduria.
Pediatric research 1978;12(4 Pt 1):256-62.