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David Carbone

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Nicholas J Giacalone; Pierre P Massion; Sandra J Olson; David P Carbone; Heidi Chen; Robert B Den; Rosana Eisenberg; Bo Lu
ALDH7A1 expression is associated with recurrence in patients with surgically resected non-small-cell lung carcinoma.
Leora Horn; Vicki L Keedy; Alan Sandler; Brady Spencer; Norma Campbell; David P Carbone; Gabe Garcia; Amy Hayes; David H Johnson
Identifying barriers associated with enrollment of patients with lung cancer into clinical trials.
Takefumi Kikuchi; Ming Li; Daniel C Liebler; Qinfeng Liu; Pierre P Massion; S M Jamshedur Rahman; Yu Shyr; Robbert J C Slebos; Xueqiong Zhang; Lisa J Zimmerman; Adriana L Gonzalez; Bradford K Harris; Mohamed Hassanein; Megan D Hoeksema; Jacob M Kaufman; Joseph M Amann; David P Carbone
In-depth proteomic analysis of nonsmall cell lung cancer to discover molecular targets and candidate biomarkers.

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2013: Nicholas J Giacalone; Pierre P Massion; Sandra J Olson; David P Carbone; Heidi Chen; Robert B Den; Rosana Eisenberg; Bo Lu
ALDH7A1 expression is associated with recurrence in patients with surgically resected non-small-cell lung carcinoma.
Future oncology (London, England) 2013;9(5):737-45.
2013: Leora Horn; Vicki L Keedy; Alan Sandler; Brady Spencer; Norma Campbell; David P Carbone; Gabe Garcia; Amy Hayes; David H Johnson
Identifying barriers associated with enrollment of patients with lung cancer into clinical trials.
Clinical lung cancer 2013;14(1):14-8.
2012: Takefumi Kikuchi; Ming Li; Daniel C Liebler; Qinfeng Liu; Pierre P Massion; S M Jamshedur Rahman; Yu Shyr; Robbert J C Slebos; Xueqiong Zhang; Lisa J Zimmerman; Adriana L Gonzalez; Bradford K Harris; Mohamed Hassanein; Megan D Hoeksema; Jacob M Kaufman; Joseph M Amann; David P Carbone
In-depth proteomic analysis of nonsmall cell lung cancer to discover molecular targets and candidate biomarkers.
Molecular & cellular proteomics : MCP 2012;11(10):916-32.
2012: Malvi Savani; Yan Guo; David P Carbone; Ildiko Csiki
Sonic hedgehog pathway expression in non-small cell lung cancer.
Therapeutic advances in medical oncology 2012;4(5):225-33.
2012: Roman Uzhachenko; Kelli Boyd; David P Carbone; Natalia Issaeva; Sergey V Ivanov; Alla V Ivanova
Tumour suppressor Fus1 provides a molecular link between inflammatory response and mitochondrial homeostasis.
The Journal of pathology 2012;227(4):456-69.
2012: Debangshu Samanta; Jacob Kaufman; David P Carbone; Pran K Datta
Long-term smoking mediated down-regulation of Smad3 induces resistance to carboplatin in non-small cell lung cancer.
Neoplasia (New York, N.Y.) 2012;14(7):644-55.
2012: Debangshu Samanta; Fei Ye; David P Carbone; Adriana L Gonzalez; Nagaraj Nagathihalli; Pran K Datta
Smoking attenuates transforming growth factor-β-mediated tumor suppression function through downregulation of Smad3 in lung cancer.
Cancer prevention research (Philadelphia, Pa.) 2012;5(3):453-63.
2012: Yunguang Sun; Artour Torossian; Zhongming Zhao; Siyuan Zheng; David P Carbone; Nicholas J Giacalone; Stephen Schleicher; Christina K Speirs; Bo Lu
Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells.
International journal of radiation oncology, biology, physics 2012;82(3):e563-72.
2012: Hirokazu Ohashi; Hiromu Suzuki; Hiroaki Taniguchi; Hiroyuki Yamamoto; Yasushi Adachi; Yoshiaki Arimura; David P Carbone; Kohzoh Imai; Katsuhiko Nosho; Yasuhisa Shinomura
Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers.
Cancer science 2012;103(2):252-61.
2011: Sunil K Halder; Amy-Joan L Ham; Govindaraj Anumanthan; David P Carbone; Yong-Jig Cho; Arunima Datta; Pran K Datta
Elucidating the mechanism of regulation of transforming growth factor β Type II receptor expression in human lung cancer cell lines.
Neoplasia (New York, N.Y.) 2011;13(10):912-22.
2011: David P Carbone
Translating cancer complexity to clinical decisions.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011;6(9):1455-6; author reply 1456-7.
2011: Hua Li; Yongfen Min; Hirokazu Ohashi; Yasushi Adachi; Yoshiaki Arimura; David P Carbone; Takao Endo; Masanori Ii; Kohzoh Imai; Choon-Taek Lee; Hiroyuki Yamamoto; Yasuhisa Shinomura
Insulin-like growth factor-I receptor blockade reduces tumor angiogenesis and enhances the effects of bevacizumab for a human gastric cancer cell line, MKN45.
Cancer 2011;117(14):3135-47.
2011: S M Jamshedur Rahman; Adriana L Gonzalez; Ming Li; Erin H Seeley; Lisa J Zimmerman; Xueqiong J Zhang; M Lisa Manier; Sandra J Olson; Ronak N Shah; Alison N Miller; Joe B Putnam; York E Miller; Wilbur A Franklin; William J Blot; David P Carbone; Yu Shyr; Richard M Caprioli; Pierre P Massion
Lung cancer diagnosis from proteomic analysis of preinvasive lesions.
Cancer research 2011;71(8):3009-17.
2011: Yunguang Sun; Luigi Moretti; Nicholas J Giacalone; Stephen Schleicher; Christina K Speirs; David P Carbone; Bo Lu
Inhibition of JAK2 signaling by TG101209 enhances radiotherapy in lung cancer models.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011;6(4):699-706.
2010: Sergey V Novitskiy; Ildiko Csiki; Yuhui Huang; David H Johnson; Eva M Harth; David P Carbone; Mikhail M Dikov
Anti-vascular endothelial growth factor treatment in combination with chemotherapy delays hematopoietic recovery due to decreased proliferation of bone marrow hematopoietic progenitor cells.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010;5(9):1410-5.
2010: David P Carbone; J Stuart Salmon; Dean Billheimer; Heidi Chen; Alan B Sandler; Heinrich Roder; Joanna Roder; Maxim Tsypin; Roy S Herbst; Anne S Tsao; Hai T Tran; Thao P Dang
VeriStrat classifier for survival and time to progression in non-small cell lung cancer (NSCLC) patients treated with erlotinib and bevacizumab.
Lung cancer (Amsterdam, Netherlands) 2010;69(3):337-40.
2010: Yujun Gan; Yue Zhang; Douglas J DiGirolamo; Jing Jiang; Xiangdong Wang; Xuemei Cao; Kurt R Zinn; David P Carbone; Thomas Landes Clemens; Stuart J Frank
Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling.
Molecular endocrinology (Baltimore, Md.) 2010;24(3):644-56.
2010: Christine H Chung; Erin H Seeley; Heinrich Roder; Julia Grigorieva; Maxim Tsypin; Joanna Roder; Barbara A Burtness; Athanassios Argiris; Arlene A Forastiere; Jill Gilbert; Barbara Murphy; Richard M Caprioli; David P Carbone; Ezra E W Cohen
Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(2):358-65.
2010: Joseph M Amann; Ju-Whei Lee; Heinrich Roder; Julie R Brahmer; Adriana Gonzalez; Joan H Schiller; David P Carbone
Genetic and proteomic features associated with survival after treatment with erlotinib in first-line therapy of non-small cell lung cancer in Eastern Cooperative Oncology Group 3503.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010;5(2):169-78.
2010: Yu Wang; Yasushi Adachi; arisa imsumran; Hiroyuki Yamamoto; Wenhua Piao; Hua Li; Masanori Ii; Yoshiaki Arimura; Mi Young Park; Dalrae Kim; Choon-Taek Lee; David P Carbone; Kohzoh Imai; Yasuhisa Shinomura
Targeting for insulin-like growth factor-I receptor with short hairpin RNA for human digestive/gastrointestinal cancers.
Journal of gastroenterology 2010;45(2):159-70.
2010: J Konishi; F Yi; X Chen; H Vo; David P Carbone; Thao P Dang
Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim.
Oncogene 2010;29(4):589-96.
2010: Luping Lin; Raymond L Mernaugh; Fuming Yi; David Blum; David P Carbone; Thao P Dang
Targeting specific regions of the Notch3 ligand-binding domain induces apoptosis and inhibits tumor growth in lung cancer.
Cancer research 2010;70(2):632-8.
2009: Luigi Moretti; David S Yu; Heidi Chen; David P Carbone; David H Johnson; Vicki L Keedy; Joe B Putnam; Alan B Sandler; Yu Shyr; Bo Lu
Prognostic factors for resected non-small cell lung cancer with pN2 status: implications for use of postoperative radiotherapy.
The oncologist 2009;14(11):1106-15.
2009: David P Carbone
Profiles in variation: lung carcinogenesis.
Cancer prevention research (Philadelphia, Pa.) 2009;2(8):695-7.
2009: Yasushi Adachi; Rong Li; Hiroyuki Yamamoto; Yongfen Min; Wenhua Piao; Yu Wang; arisa imsumran; Hua Li; Yoshiaki Arimura; Choon-Taek Lee; Kohzoh Imai; David P Carbone; Yasuhisa Shinomura
Insulin-like growth factor-I receptor blockade reduces the invasiveness of gastrointestinal cancers via blocking production of matrilysin.
Carcinogenesis 2009;30(8):1305-13.
2009: Robert Mutter; Bo Lu; David P Carbone; Ildiko Csiki; Luigi Moretti; David H Johnson; Jason D Morrow; Alan B Sandler; Yu Shyr; Fei Ye; Hak Choy
A phase II study of celecoxib in combination with paclitaxel, carboplatin, and radiotherapy for patients with inoperable stage IIIA/B non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(6):2158-65.
2008: Baogang J Xu; Adriana L Gonzalez; Takefumi Kikuchi; Kiyoshi Yanagisawa; Pierre P Massion; Huiyun Wu; Stephen E Mason; Sandra J Olson; Yu Shyr; David P Carbone; Richard M Caprioli
MALDI-MS derived prognostic protein markers for resected non-small cell lung cancer.
Proteomics. Clinical applications 2008;2(10-11):1508-17.
2008: Vicki Keedy; Wei Wang; Joan Schiller; Sunil Chada; Bonnie S Slovis; Keith Coffee; John Worrell; Lyn A Thet; David H Johnson; David P Carbone
Phase I study of adenovirus p53 administered by bronchoalveolar lavage in patients with bronchioloalveolar cell lung carcinoma: ECOG 6597.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(25):4166-71.
2008: Sergey Ryzhov; Sergey Novitskiy; Rinat Zaynagetdinov; Anna E Goldstein; David P Carbone; Italo Biaggioni; Mikhail M Dikov; Igor Feoktistov
Host A(2B) adenosine receptors promote carcinoma growth.
Neoplasia (New York, N.Y.) 2008;10(9):987-95.
2008: Wenhua Piao; Yu Wang; Yasushi Adachi; Hiroyuki Yamamoto; Rong Li; arisa imsumran; Hua Li; Tadateru Maehata; Masanori Ii; Yoshiaki Arimura; Choon-Taek Lee; Yasuhisa Shinomura; David P Carbone; Kohzoh Imai
Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas.
Molecular cancer therapeutics 2008;7(6):1483-93.
2008: Li Yang; Jianhua Huang; Xiubao Ren; Agnieszka E Gorska; Anna Chytil; Mary E Aakre; David P Carbone; Lynn M Matrisian; Ann Richmond; P Charles Lin; Harold L Moses
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis.
Cancer cell 2008;13(1):23-35.
2007: Pinar Yildiz; Yu Shyr; Jamshedur S M Rahman; Noel R Wardwell; Lisa J Zimmerman; Bashar Shakhtour; William H Gray; Shuo Chen; Ming Li; Heinrich Roder; Daniel C Liebler; William L Bigbee; Jill M Siegfried; Joel L Weissfeld; Adriana L Gonzalez; Mathew Ninan; David H Johnson; David P Carbone; Richard M Caprioli; Pierre P Massion
Diagnostic accuracy of MALDI mass spectrometric analysis of unfractionated serum in lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2007;2(10):893-901.
2007: Jeffrey M Albert; Adriana Gonzalez; Pierre P Massion; Heidi Chen; Sandra J Olson; Yu Shyr; Roberto Diaz; Eric S Lambright; Alan B Sandler; David P Carbone; Joe B Putnam; David H Johnson; Bo Lu
Cytoplasmic clusterin expression is associated with longer survival in patients with resected non small cell lung cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(9):1845-51.
2007: Jun Konishi; Keiko S Kawaguchi; Huan Vo; Nobuhiro Haruki; Adriana Gonzalez; David P Carbone; Thao P Dang
Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.
Cancer research 2007;67(17):8051-7.
2007: Li Yang; Joseph M Amann; Takefumi Kikuchi; Rut Porta; Marta Guix; Adriana Gonzalez; Kyung-Ho Park; Dean Billheimer; Carlos L Arteaga; Hsin-Hsiung Tai; Raymond DuBois; David P Carbone; David H Johnson
Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer.
Cancer research 2007;67(12):5587-93.
2007: Fumiko Taguchi; Benjamin Solomon; Vanesa Gregorc; Heinrich Roder; Robert Gray; Kazuo Kasahara; Makoto Nishio; Julie R Brahmer; Anna Spreafico; Vienna Ludovini; Pierre P Massion; Rafal Dziadziuszko; Joan Schiller; Julia Grigorieva; Maxim Tsypin; Stephen W Hunsucker; Richard Caprioli; Mark W Duncan; Fred R Hirsch; Paul A Bunn; David P Carbone
Mass spectrometry to classify non-small-cell lung cancer patients for clinical outcome after treatment with epidermal growth factor receptor tyrosine kinase inhibitors: a multicohort cross-institutional study.
Journal of the National Cancer Institute 2007;99(11):838-46.
2007: arisa imsumran; Yasushi Adachi; Hiroyuki Yamamoto; Rong Li; Yu Wang; Yongfen Min; Wenhua Piao; Katsuhiko Nosho; Yoshiaki Arimura; Yasuhisa Shinomura; Masao Hosokawa; Choon-Taek Lee; David P Carbone; Kohzoh Imai
Insulin-like growth factor-I receptor as a marker for prognosis and a therapeutic target in human esophageal squamous cell carcinoma.
Carcinogenesis 2007;28(5):947-56.
2007: Yoon-Jin Lee; arisa imsumran; Mi-Young Park; Sung-Youn Kwon; Ho Il Yoon; Jae-Ho Lee; Chul-Gyu Yoo; Young Whan Kim; Sung Koo Han; Young-Soo Shim; Wenhua Piao; Hiroyuki Yamamoto; Yasushi Adachi; David P Carbone; Choon-Taek Lee
Adenovirus expressing shRNA to IGF-1R enhances the chemosensitivity of lung cancer cell lines by blocking IGF-1 pathway.
Lung cancer (Amsterdam, Netherlands) 2007;55(3):279-86.
2007: Eric T Shinohara; Adriana Gonzalez; Pierre P Massion; Sandra J Olson; Jeffrey M Albert; Yu Shyr; David P Carbone; David H Johnson; Dennis E Hallahan; Bo Lu
PDGFR-beta expression in small cell lung cancer patients.
International journal of radiation oncology, biology, physics 2007;67(2):431-7.
2007: Takefumi Kikuchi; David P Carbone
Proteomics analysis in lung cancer: challenges and opportunities.
Respirology (Carlton, Vic.) 2007;12(1):22-8.
2007: Christine H Chung; Shawn Levy; Pierre Chaurand; David P Carbone
Genomics and proteomics: emerging technologies in clinical cancer research.
Critical reviews in oncology/hematology 2007;61(1):1-25.
2006: Joseph M Amann; Pierre Chaurand; Adriana Gonzalez; James A Mobley; Pierre P Massion; David P Carbone; Richard M Caprioli
Selective profiling of proteins in lung cancer cells from fine-needle aspirates by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(17):5142-50.
2006: Heath Acuff Elrod; Mark Sinnamon; Barbara Fingleton; Braden Boone; Shawn Levy; Xiwu Chen; Ambra Pozzi; David P Carbone; Donald R Schwartz; Kamiar Moin; Bonnie F Sloane; Lynn M Matrisian
Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer.
Cancer research 2006;66(16):7968-75.
2006: David I Rosenthal; Clifton David Fuller; Mitchell Machtay; Kenneth M Algazy; Dan M Meyer; Larry R Kaiser; Denise A Yardley; Megan E Loiacano; David P Carbone
Phase I study of Paclitaxel given by seven-week continuous infusion concurrent with radiation therapy for locally advanced non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006;1(1):38-45.
2006: Choon-Taek Lee; Yoon-Jin Lee; Sung-Youn Kwon; Jaeho Lee; Kwang Il Kim; Kyung-Ho Park; Joo Hyun Kang; Chul-Gyu Yoo; Young Whan Kim; Sung Koo Han; June-Key Chung; Young-Soo Shim; David T Curiel; David P Carbone
In vivo imaging of adenovirus transduction and enhanced therapeutic efficacy of combination therapy with conditionally replicating adenovirus and adenovirus-p27.
Cancer research 2006;66(1):372-7.
2006: Ildiko Csiki; Kiyoshi Yanagisawa; Nobuhiro Haruki; Sorena Nadaf; Jason D Morrow; David H Johnson; David P Carbone
Thioredoxin-1 modulates transcription of cyclooxygenase-2 via hypoxia-inducible factor-1alpha in non-small cell lung cancer.
Cancer research 2006;66(1):143-50.
2005: S M Jamshedur Rahman; Yu Shyr; Pinar Yildiz; Adriana L Gonzalez; Huiming Li; Xueqiong Zhang; Pierre Chaurand; Kiyoshi Yanagisawa; Bonnie S Slovis; Robert F Miller; Mathew Ninan; York E Miller; Wilbur A Franklin; Richard M Caprioli; David P Carbone; Pierre P Massion
Proteomic patterns of preinvasive bronchial lesions.
American journal of respiratory and critical care medicine 2005;172(12):1556-62.
2005: Govindaraj Anumanthan; Sunil K Halder; H Osada; T Takahashi; Pierre P Massion; David P Carbone; Pran K Datta
Restoration of TGF-beta signalling reduces tumorigenicity in human lung cancer cells.
British journal of cancer 2005;93(10):1157-67.
2005: Ildiko Csiki; Jason D Morrow; Alan B Sandler; Yu Shyr; John Oates; Myles K Williams; Thao Dang; David P Carbone; David H Johnson
Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: a phase II trial of celecoxib and docetaxel.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(18):6634-40.
2005: David P Carbone; I Frank Ciernik; Michael J Kelley; M Charles Smith; Sorena Nadaf; Denise Kavanaugh; V Ellen Maher; Michael Stipanov; David Contois; Bruce E Johnson; C David Pendleton; Burkhardt Seifert; Charley Carter; Elizabeth J Read; Jay Greenblatt; Lois E Top; Morris I Kelsey; John D Minna; Jay A Berzofsky
Immunization with mutant p53- and K-ras-derived peptides in cancer patients: immune response and clinical outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(22):5099-107.
2005: Nobuhiro Haruki; Keiko S Kawaguchi; Shannon Eichenberger; Pierre P Massion; Sandra Olson; Adriana Gonzalez; David P Carbone; Thao P Dang
Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers.
Cancer research 2005;65(9):3555-61.
2005: Yongfen Min; Yasushi Adachi; Hiroyuki Yamamoto; arisa imsumran; Yoshiaki Arimura; Toshiaki Endo; Yuji Hinoda; Choon-Taek Lee; Sorena Nadaf; David P Carbone; Kohzoh Imai
Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts.
Gut 2005;54(5):591-600.
2005: Eric T Shinohara; Adriana Gonzalez; Pierre P Massion; Heidi Chen; Ming Li; Andrea S Freyer; Sandra J Olson; Jeremiah J Andersen; Yu Shyr; David P Carbone; David H Johnson; Dennis E Hallahan; Bo Lu
Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma.
Cancer 2005;103(8):1685-92.
2005: Roy S Herbst; David H Johnson; Eric Mininberg; David P Carbone; Ted Henderson; Edward S Kim; George R Blumenschein; Jack J Lee; Diane D Liu; Mylene T Truong; Waun Ki Hong; Hai Tran; Anne S Tsao; Dong Xie; David A Ramies; Robert Mass; Somasekar Seshagiri; David A Eberhard; Sean K Kelley; Alan B Sandler
Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(11):2544-55.
2005: Mikhail M Dikov; Joyce E Ohm; Neelanjan Ray; Elena E Tchekneva; Jared Burlison; Drew Moghanaki; Sorena Nadaf; David P Carbone
Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(1):215-22.
2004: Li Yang; Laura M DeBusk; Koari Fukuda; Barbara Fingleton; Brenda Green-Jarvis; Yu Shyr; Lynn M Matrisian; David P Carbone; P Charles Lin
Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis.
Cancer cell 2004;6(4):409-21.
2004: Choon-Taek Lee; Kyung-Ho Park; Kiyoshi Yanagisawa; Yasushi Adachi; Joyce E Ohm; Sorena Nadaf; Mikhail M Dikov; David T Curiel; David P Carbone
Combination therapy with conditionally replicating adenovirus and replication defective adenovirus.
Cancer research 2004;64(18):6660-5.
2004: B Lu; A Gonzalez; Pierre P Massion; Yu Shyr; Bashar Shaktour; David P Carbone; Dennis E Hallahan
Nuclear survivin as a biomarker for non-small-cell lung cancer.
British journal of cancer 2004;91(3):537-40.
2004: Pierre P Massion; Peter M Taflan; S M Jamshedur Rahman; Pinar Yildiz; Yu Shyr; David P Carbone; Adriana L Gonzalez
Role of p63 amplification and overexpression in lung cancer development.
Chest 2004;125(5 Suppl):102S.
2004: Yasushi Adachi; Choon-Taek Lee; David P Carbone
Genetic blockade of the insulin-like growth factor 1 receptor for human malignancy.
Novartis Foundation symposium 2004;262():177-89; discussion 190-2, 265-8.
2004: Li Yang; David P Carbone
Tumor-host immune interactions and dendritic cell dysfunction.
Advances in cancer research 2004;92():13-27.
2003: Pierre P Massion; Peter M Taflan; S M Jamshedur Rahman; Pinar Yildiz; Yu Shyr; Mary Edgerton; Matthew D Westfall; John R Roberts; Jennifer A Pietenpol; David P Carbone; Adriana L Gonzalez
Significance of p63 amplification and overexpression in lung cancer development and prognosis.
Cancer research 2003;63(21):7113-21.
2003: Noboru Yamagata; Yu Shyr; Kiyoshi Yanagisawa; Mary Edgerton; Thao P Dang; Adriana Gonzalez; Sorena Nadaf; Paul Larsen; John R Roberts; Jonathan C Nesbitt; Roy Jensen; Shawn Levy; Jason Moore; John D Minna; David P Carbone
A training-testing approach to the molecular classification of resected non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):4695-704.
2003: Yongfen Min; Yasushi Adachi; Hiroyuki Yamamoto; Hideto Ito; Fumio Itoh; Choon-Taek Lee; Sorena Nadaf; David P Carbone; Kohzoh Imai
Genetic blockade of the insulin-like growth factor-I receptor: a promising strategy for human pancreatic cancer.
Cancer research 2003;63(19):6432-41.
2003: Roy S Herbst; Lisa A Hammond; David P Carbone; Hai T Tran; Kenneth J Holroyd; Avinash Desai; Jon I Williams; B Nebiyou Bekele; Howard Hait; Victoria Allgood; Stephen Solomon; Joan H Schiller
A phase I/IIA trial of continuous five-day infusion of squalamine lactate (MSI-1256F) plus carboplatin and paclitaxel in patients with advanced non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(11):4108-15.
2003: Kiyoshi Yanagisawa; Baogang J Xu; David P Carbone; Richard M Caprioli
Molecular fingerprinting in human lung cancer.
Clinical lung cancer 2003;5(2):113-8.
2003: Kiyoshi Yanagisawa; Yu Shyr; Baogang J Xu; Pierre P Massion; Paul H Larsen; Bill C White; John R Roberts; Mary Edgerton; Adriana Gonzalez; Sorena Nadaf; Jason Moore; Richard M Caprioli; David P Carbone
Proteomic patterns of tumour subsets in non-small-cell lung cancer.
Lancet 2003;362(9382):433-9.
2003: Joyce E Ohm; Dmitry I Gabrilovich; Gregory D Sempowski; Ekaterina Kisseleva; Kelly S Parman; Sorena Nadaf; David P Carbone
VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression.
Blood 2003;101(12):4878-86.
2003: Thao P Dang; Shannon Eichenberger; Adriana Gonzalez; Sandra Olson; David P Carbone
Constitutive activation of Notch3 inhibits terminal epithelial differentiation in lungs of transgenic mice.
Oncogene 2003;22(13):1988-97.
2003: Li Yang; Noboru Yamagata; Rajwardhan Yadav; Suzanne Brandon; Regina L Courtney; Jason D Morrow; Yu Shyr; Mark Boothby; Sebastian JOYCE; David P Carbone; Richard M Breyer
Cancer-associated immunodeficiency and dendritic cell abnormalities mediated by the prostaglandin EP2 receptor.
The Journal of clinical investigation 2003;111(5):727-35.
2003: Pierre P Massion; David P Carbone
The molecular basis of lung cancer: molecular abnormalities and therapeutic implications.
Respiratory research 2003;4():12.
2003: Choon-Taek Lee; Kyung-Ho Park; Yasushi Adachi; Ja Young Seol; Chul-Gyu Yoo; Young Whan Kim; Sung Koo Han; Young-Soo Shim; Keith Coffee; Mikhail M Dikov; David P Carbone
Recombinant adenoviruses expressing dominant negative insulin-like growth factor-I receptor demonstrate antitumor effects on lung cancer.
Cancer gene therapy 2003;10(1):57-63.
2002: Yasushi Adachi; Choon-Taek Lee; Keith Coffee; Noboru Yamagata; Joyce E Ohm; Kyung-Ho Park; Mikhail M Dikov; Sorena Nadaf; Carlos L Arteaga; David P Carbone
Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines.
Gastroenterology 2002;123(4):1191-204.
2002: Dmitry I Gabrilovich; Pingyan Cheng; Yuhong Fan; Bin Yu; Ekaterina Nikitina; Allen Sirotkin; Michael R Shurin; Tsunehiro Oyama; Yasushi Adachi; Sorena Nadaf; David P Carbone; Arthur I Skoultchi
H1(0) histone and differentiation of dendritic cells. A molecular target for tumor-derived factors.
Journal of leukocyte biology 2002;72(2):285-96.
2002: Stephen G Swisher; Jack A Roth; David P Carbone
Genetic and immunologic therapies for lung cancer.
Seminars in oncology 2002;29(1 Suppl 4):95-101.
2002: Joyce E Ohm; David P Carbone
Immune dysfunction in cancer patients.
Oncology (Williston Park, N.Y.) 2002;16(1 Suppl 1):11-8.
2001: Mikhail M Dikov; T Oyama; P Cheng; T Takahashi; K Takahashi; T Sepetavec; B Edwards; Yasushi Adachi; Sorena Nadaf; T Daniel; Dmitry I Gabrilovich; David P Carbone
Vascular endothelial growth factor effects on nuclear factor-kappaB activation in hematopoietic progenitor cells.
Cancer research 2001;61(5):2015-21.
2001: David I Rosenthal; Jason H Lee; Robert J Sinard; Denise Yardley; Mitchell Machtay; D M Rosen; Merrill J Egorin; Randal S Weber; Gregory S Weinstein; Ara A Chalian; L K Miller; Eugene P Frenkel; David P Carbone
Phase I study of paclitaxel given by seven-week continuous infusion concurrent with radiation therapy for locally advanced squamous cell carcinoma of the head and neck.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(5):1363-73.
2001: Joyce E Ohm; David P Carbone
VEGF as a mediator of tumor-associated immunodeficiency.
Immunologic research 2001;23(2-3):263-72.
2001: B Almand; David P Carbone
Biological considerations in lung cancer.
Cancer treatment and research 2001;105():1-30.
2001: Madan H Jagasia; C J Langer; David H Johnson; F Yunus; J S Rodgers; LL Schlabach; A G Cohen; Yu Shyr; David P Carbone; Russell F DeVore
Weekly irinotecan and cisplatin in advanced non-small cell lung cancer: a multicenter phase II study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(1):68-73.
2001: Ekaterina Nikitina; JI Clark; J Van Beynen; S Chada; A K Virmani; David P Carbone; Dmitry I Gabrilovich
Dendritic cells transduced with full-length wild-type p53 generate antitumor cytotoxic T lymphocytes from peripheral blood of cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(1):127-35.
2001: B Almand; JI Clark; Ekaterina Nikitina; J van Beynen; Nicholas R English; Stella C Knight; David P Carbone; Dmitry I Gabrilovich
Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):678-89.
2000: David I Rosenthal; Carlos R Becerra; R D Toto; David P Carbone; Eugene P Frenkel
Reversible renal toxicity resulting from high single doses of the new radiosensitizer gadolinium texaphyrin.
American journal of clinical oncology 2000;23(6):593-8.
2000: Masaki Terabe; S Matsui; Nancy Noben-Trauth; H Chen; C Watson; Debra D Donaldson; David P Carbone; William Paul; Jay A Berzofsky
NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway.
Nature immunology 2000;1(6):515-20.
2000: Thao P Dang; A F Gazdar; A K Virmani; T Sepetavec; K R Hande; John D Minna; John R Roberts; David P Carbone
Chromosome 19 translocation, overexpression of Notch3, and human lung cancer.
Journal of the National Cancer Institute 2000;92(16):1355-7.
2000: B Almand; John R Resser; B Lindman; Sorena Nadaf; JI Clark; E D Kwon; David P Carbone; Dmitry I Gabrilovich
Clinical significance of defective dendritic cell differentiation in cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):1755-66.
1999: David P Carbone
Molecular modalities in the treatment of lung cancer.
Oncology (Williston Park, N.Y.) 1999;13(10 Suppl 5):142-7.
1999: Dmitry I Gabrilovich; T Ishida; Sorena Nadaf; Joyce E Ohm; David P Carbone
Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10):2963-70.
1999: Joyce E Ohm; Michael R Shurin; Clemens Esche; Michael T Lotze; David P Carbone; Dmitry I Gabrilovich
Effect of vascular endothelial growth factor and FLT3 ligand on dendritic cell generation in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3260-8.
1999: T Ishida; S Chada; M Stipanov; Sorena Nadaf; F I Ciernik; Dmitry I Gabrilovich; David P Carbone
Dendritic cells transduced with wild-type p53 gene elicit potent anti-tumour immune responses.
Clinical and experimental immunology 1999;117(2):244-51.
1999: S Matsui; Jeffrey D Ahlers; A O Vortmeyer; Masaki Terabe; T Tsukui; David P Carbone; L A Liotta; Jay A Berzofsky
A model for CD8+ CTL tumor immunosurveillance and regulation of tumor escape by CD4 T cells through an effect on quality of CTL.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):184-93.
1999: George P Amorino; Michael L Freeman; David P Carbone; D E Lebwohl; Hak Choy
Radiopotentiation by the oral platinum agent, JM216: role of repair inhibition.
International journal of radiation oncology, biology, physics 1999;44(2):399-405.
1999: David I Rosenthal; P Nurenberg; Carlos R Becerra; Eugene P Frenkel; David P Carbone; B L Lum; R Miller; J Engel; S Young; D Miles; Markus F Renschler
A phase I single-dose trial of gadolinium texaphyrin (Gd-Tex), a tumor selective radiation sensitizer detectable by magnetic resonance imaging.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(4):739-45.
1999: J E Dowell; Robert J Sinard; Denise Yardley; Victor M Aviles; Mitchell Machtay; Randal S Weber; Gregory S Weinstein; Ara A Chalian; David P Carbone; David I Rosenthal
Seven-week continuous-infusion paclitaxel concurrent with radiation therapy for locally advanced non-small cell lung and head and neck cancers.
Seminars in radiation oncology 1999;9(2 Suppl 1):97-101.
1998: Dmitry I Gabrilovich; T Ishida; T Oyama; S Ran; Vladimir Kravtsov; Sorena Nadaf; David P Carbone
Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo.
Blood 1998;92(11):4150-66.
1998: T Ishida; T Oyama; David P Carbone; Dmitry I Gabrilovich
Defective function of Langerhans cells in tumor-bearing animals is the result of defective maturation from hemopoietic progenitors.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4842-51.
1998: J H Lee; Choon-Taek Lee; Chul-Gyu Yoo; Y K Hong; C M Kim; Sung Koo Han; Young-Soo Shim; David P Carbone; Young Whan Kim
The inhibitory effect of adenovirus-mediated p16INK4a gene transfer on the proliferation of lung cancer cell line.
Anticancer research 1998;18(5A):3257-61.
1998: John R Resser; David P Carbone
Immunotherapy of head and neck cancer.
Current opinion in oncology 1998;10(3):226-32.
1998: T Oyama; S Ran; T Ishida; Sorena Nadaf; LD Kerr; David P Carbone; Dmitry I Gabrilovich
Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(3):1224-32.
1997: David I Rosenthal; Robert J Sinard; O Okani; J Corak; Denise Kavanaugh; B Kamen; FM Vuitch; AF Gazdar; J Griener; E P Frenkel; David P Carbone
Seven-week continuous-infusion paclitaxel with concurrent radiotherapy for locally advanced head and neck squamous cell cancer: a phase I study.
Seminars in oncology 1997;24(6 Suppl 19):S19-67-S19-71.
1997: David I Rosenthal; O Okani; J Corak; Denise Kavanaugh; B Kamen; FM Vuitch; AF Gazdar; J Greiner; E F Frenkel; David P Carbone
Seven-week continuous-infusion paclitaxel plus concurrent radiation therapy for locally advanced non-small cell lung cancer: a phase I study.
Seminars in oncology 1997;24(4 Suppl 12):S12-96-S12-100.
1997: David P Carbone
The biology of lung cancer.
Seminars in oncology 1997;24(4):388-401.
1997: M C Smith; C David Pendleton; V Ellen Maher; M J Kelley; David P Carbone; Jay A Berzofsky
Oncogenic mutations in ras create HLA-A2.1 binding peptides but affect their extracellular antigen processing.
International immunology 1997;9(8):1085-93.
1997: Dmitry I Gabrilovich; J Corak; I Frank Ciernik; Denise Kavanaugh; David P Carbone
Decreased antigen presentation by dendritic cells in patients with breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(3):483-90.
1997: David I Rosenthal; O Okani; J M Truelson; H Fathallah-Shaykh; FM Vuitch; AF Gazdar; J Griener; M Landay; D Mendelsohn; J Tourville; L Hamilton; K Y Orr; J McWhorter; David P Carbone
Intensive radiation therapy concurrent with up to 7-week continuous-infusion paclitaxel for locally advanced solid tumors: phase I studies.
Seminars in oncology 1997;24(1 Suppl 2):S2-81-S2-84.
1996: Dmitry I Gabrilovich; H T Cunningham; David P Carbone
IL-12 and mutant P53 peptide-pulsed dendritic cells for the specific immunotherapy of cancer.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1996;19(6):414-8.
1996: Dmitry I Gabrilovich; H L Chen; K R Girgis; H T Cunningham; G M Meny; Sorena Nadaf; Denise Kavanaugh; David P Carbone
Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells.
Nature medicine 1996;2(10):1096-103.
1996: H L Chen; Dmitry I Gabrilovich; Arvind K Virmani; I Ratnani; K R Girgis; S Nadaf-Rahrov; M Fernandez-Viña; David P Carbone
Structural and functional analysis of beta2 microglobulin abnormalities in human lung and breast cancer.
International journal of cancer. Journal international du cancer 1996;67(6):756-63.
1996: T Tsukui; Allan Hildesheim; Mark Schiffman; Joseph Lucci; D Contois; P Lawler; Brenda B Rush; Attila T Lorincz; A Corrigan; Robert D Burk; W Qu; M A Marshall; Dean L Mann; Mary Carrington; M Clerici; G M Shearer; David P Carbone; David R Scott; R A Houghten; Jay A Berzofsky
Interleukin 2 production in vitro by peripheral lymphocytes in response to human papillomavirus-derived peptides: correlation with cervical pathology.
Cancer research 1996;56(17):3967-74.
1996: Denise Kavanaugh; David P Carbone
Immunologic dysfunction in cancer.
Hematology/oncology clinics of North America 1996;10(4):927-51.
1996: C T Lee; I F Ciernik; S Wu; De-chu C Tang; H L Chen; John M Truelson; David P Carbone
Increased immunogenicity of tumors bearing mutant p53 and P1A epitopes after transduction of B7-1 via recombinant adenovirus.
Cancer gene therapy 1996;3(4):238-44.
1996: C T Lee; S Wu; Dmitry I Gabrilovich; H Chen; S Nadaf-Rahrov; I F Ciernik; David P Carbone
Antitumor effects of an adenovirus expressing antisense insulin-like growth factor I receptor on human lung cancer cell lines.
Cancer research 1996;56(13):3038-41.
1996: Dmitry I Gabrilovich; Sorena Nadaf; J Corak; J A Berzofsky; David P Carbone
Dendritic cells in antitumor immune responses. II. Dendritic cells grown from bone marrow precursors, but not mature DC from tumor-bearing mice, are effective antigen carriers in the therapy of established tumors.
Cellular immunology 1996;170(1):111-9.
1996: Dmitry I Gabrilovich; I F Ciernik; David P Carbone
Dendritic cells in antitumor immune responses. I. Defective antigen presentation in tumor-bearing hosts.
Cellular immunology 1996;170(1):101-10.
1996: I F Ciernik; B H Krayenbühl; David P Carbone
Puncture-mediated gene transfer to the skin.
Human gene therapy 1996;7(8):893-9.
1996: I F Ciernik; J A Berzofsky; David P Carbone
Human lung cancer cells endogenously expressing mutant p53 process and present the mutant epitope and are lysed by mutant-specific cytotoxic T lymphocytes.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(5):877-82.
1996: I F Ciernik; J A Berzofsky; David P Carbone
Induction of cytotoxic T lymphocytes and antitumor immunity with DNA vaccines expressing single T cell epitopes.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(7):2369-75.
1996: De-chu C Tang; A F Gazdar; David P Carbone
In vivo cytotoxicity assay for assessing immunity.
Journal of immunological methods 1996;189(2):173-82.
1995: Joseph T Santoso; De-chu C Tang; S B Lane; Jaclyn Y Hung; D J Reed; Carolyn Y Muller; David P Carbone; Joseph Lucci; David S Miller; J Michael Mathis
Adenovirus-based p53 gene therapy in ovarian cancer.
Gynecologic oncology 1995;59(2):171-8.
1995: I F Ciernik; B H Krayenbühl Ciernik; Clay J Cockerell; John D Minna; Adi F Gazdar; David P Carbone
Expression of transforming growth factor beta and transforming growth factor beta receptors on AIDS-associated Kaposi's sarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(10):1119-24.
1995: I F Ciernik; J Berzofsky; David P Carbone
Mutant oncopeptide immunization induces CTL specifically lysing tumor cells endogenously expressing the corresponding intact mutant p53.
Hybridoma 1995;14(2):139-42.
1995: David I Rosenthal; David P Carbone
Taxol plus radiation for head and neck cancer.
The Journal of infusional chemotherapy 1995;5(2):46-54.
1994: Yoshitaka Sekido; SA Bader; David P Carbone; Bruce E Johnson; John D Minna
Molecular analysis of the HuD gene encoding a paraneoplastic encephalomyelitis antigen in human lung cancer cell lines.
Cancer research 1994;54(18):4988-92.
1994: E A Wiedenfeld; M Fernandez-Viña; J A Berzofsky; David P Carbone
Evidence for selection against human lung cancers bearing p53 missense mutations which occur within the HLA A*0201 peptide consensus motif.
Cancer research 1994;54(5):1175-7.
1994: De-chu C Tang; Stephan Johnston; David P Carbone
Butyrate-inducible and tumor-restricted gene expression by adenovirus vectors.
Cancer gene therapy 1994;1(1):15-20.
1994: Adi F Gazdar; SA Bader; Jaclyn Y Hung; Y Kishimoto; Yoshitaka Sekido; K Sugio; Arvind K Virmani; Jason Fleming; David P Carbone; John D Minna
Molecular genetic changes found in human lung cancer and its precursor lesions.
Cold Spring Harbor symposia on quantitative biology 1994;59():565-72.
1993: S F Winter; Yoshitaka Sekido; John D Minna; D McIntire; Bruce E Johnson; Adi F Gazdar; David P Carbone
Antibodies against autologous tumor cell proteins in patients with small-cell lung cancer: association with improved survival.
Journal of the National Cancer Institute 1993;85(24):2012-8.
1993: De-chu C Tang; David P Carbone
Potential application of gene therapy to lung cancer.
Seminars in oncology 1993;20(4):368-73.
1993: M Yanuck; David P Carbone; C David Pendleton; T Tsukui; S F Winter; John D Minna; Jay A Berzofsky
A mutant p53 tumor suppressor protein is a target for peptide-induced CD8+ cytotoxic T-cells.
Cancer research 1993;53(14):3257-61.
1993: David P Carbone
Oncogenes and tumor suppressor genes.
Hospital practice (Office ed.) 1993;28(6):145-8, 153-6, 161.
1992: S F Winter; John D Minna; Bruce E Johnson; T Takahashi; Adi F Gazdar; David P Carbone
Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation.
Cancer research 1992;52(15):4168-74.
1992: D D'Amico; David P Carbone; Bruce E Johnson; Meltzer Stephen J.; John D Minna
Polymorphic sites within the MCC and APC loci reveal very frequent loss of heterozygosity in human small cell lung cancer.
Cancer research 1992;52(7):1996-9.
1992: David P Carbone; John D Minna
The molecular genetics of lung cancer.
Advances in internal medicine 1992;37():153-71.
1991: David P Carbone; A M Koros; RI Linnoila; P Jewett; Adi F Gazdar
Neural cell adhesion molecule expression and messenger RNA splicing patterns in lung cancer cell lines are correlated with neuroendocrine phenotype and growth morphology.
Cancer research 1991;51(22):6142-9.