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takeshi sugaya

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Akihiko Kimura; Yuko Ishida; Takashi Wada; Tomoko Hisaoka; Yoshihiro Morikawa; takeshi sugaya; Naofumi Mukaida; Toshikazu Kondo
The absence of interleukin-6 enhanced arsenite-induced renal injury by promoting autophagy of tubular epithelial cells with aberrant extracellular signal-regulated kinase activation.
Stine E Nielsen; takeshi sugaya; Lise Tarnow; Maria Lajer; Katrine J Schjoedt; Anne Sofie Astrup; Tsuneharu Baba; Hans-Henrik Parving; Peter Rossing
Tubular and glomerular injury in diabetes and the impact of ACE inhibition.
Tsukasa Nakamura; Nobuharu Fujiwara; takeshi sugaya; Yoshihiko Ueda; Hikaru Koide
Effect of red wine on urinary protein, 8-hydroxydeoxyguanosine, and liver-type fatty acid-binding protein excretion in patients with diabetic nephropathy.

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2010: Akihiko Kimura; Yuko Ishida; Takashi Wada; Tomoko Hisaoka; Yoshihiro Morikawa; takeshi sugaya; Naofumi Mukaida; Toshikazu Kondo
The absence of interleukin-6 enhanced arsenite-induced renal injury by promoting autophagy of tubular epithelial cells with aberrant extracellular signal-regulated kinase activation.
The American journal of pathology 2010;176(1):40-50.
2009: Stine E Nielsen; takeshi sugaya; Lise Tarnow; Maria Lajer; Katrine J Schjoedt; Anne Sofie Astrup; Tsuneharu Baba; Hans-Henrik Parving; Peter Rossing
Tubular and glomerular injury in diabetes and the impact of ACE inhibition.
Diabetes care 2009;32(9):1684-8.
2009: Tsukasa Nakamura; Nobuharu Fujiwara; takeshi sugaya; Yoshihiko Ueda; Hikaru Koide
Effect of red wine on urinary protein, 8-hydroxydeoxyguanosine, and liver-type fatty acid-binding protein excretion in patients with diabetic nephropathy.
Metabolism: clinical and experimental 2009;58(8):1185-90.
2009: Tsukasa Nakamura; takeshi sugaya; Hikaru Koide
Urinary liver-type fatty acid-binding protein in septic shock: effect of polymyxin B-immobilized fiber hemoperfusion.
Shock (Augusta, Ga.) 2009;31(5):454-9.
2009: Eisei Noiri; Kent Doi; Kousuke Negishi; Tamami Tanaka; Yoshifumi Hamasaki; Toshiro Fujita; Didier Portilla; takeshi sugaya
Urinary fatty acid-binding protein 1: an early predictive biomarker of kidney injury.
American journal of physiology. Renal physiology 2009;296(4):F669-79.
2009: Atsuko Kamijo-Ikemori; takeshi sugaya; Ayako Sekizuka; Kazuaki Hirata; Kenjiro Kimura
Amelioration of diabetic tubulointerstitial damage in liver-type fatty acid-binding protein transgenic mice.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(3):788-800.
2008: M Tanaka; Yusuke Suzuki; Isao Shirato; Hisatsugu Takahara; T Shibata; takeshi sugaya; K Shimamoto; Satoshi Horikoshi; Yasuhiko Tomino
Tubular epithelial cells have the capacity to transdifferentiate into CD68-positive macrophage-like cells by oxidative stress.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2008;57(12):593-600.
2008: Tsukasa Nakamura; T Inoue; N Fujiwara; Yasuhiro Kawagoe; takeshi sugaya; Y Ueda; H Koide; K Node
Additional renoprotective effects of azelnidipine combined with angiotensin receptor blockers in patients with diabetic nephropathy.
Clinical nephrology 2008;70(5):385-92.
2008: Tsukasa Nakamura; Teruo Inoue; takeshi sugaya; Yasuhiro Kawagoe; Tsukasa Suzuki; Yoshihiko Ueda; Koichi Node
Renoprotective effect of telmisartan in patients with chronic kidney disease.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2008;30(7):662-72.
2008: Katsutoshi Yayama; Ryoko Miyagi; Kaori Sugiyama; takeshi sugaya; Akiyoshi Fukamizu; Hiroshi Okamoto
Angiotensin II regulates liver regeneration via type 1 receptor following partial hepatectomy in mice.
Biological & pharmaceutical bulletin 2008;31(7):1356-61.
2008: Hideki Kato; Junji Ishida; Katsumasa Nagano; Kaori Honjo; takeshi sugaya; Norifumi Takeda; Fumihiro Sugiyama; Ken-ichi Yagami; Toshiro Fujita; Masaomi Nangaku; Akiyoshi Fukamizu
Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells.
Laboratory investigation; a journal of technical methods and pathology 2008;88(7):731-9.
2008: Hirokazu Okada; Tsutomu Inoue; Tomohiro Kikuta; Nobutaka Kato; Yoshihiko Kanno; Narumi Hirosawa; Yasushi Sakamoto; takeshi sugaya; Hiromichi Suzuki
Poly(ADP-ribose) polymerase-1 enhances transcription of the profibrotic CCN2 gene.
Journal of the American Society of Nephrology : JASN 2008;19(5):933-42.
2008: Kazuo Nakamura; Kimihiro Ito; Yukio Kato; takeshi sugaya; Yoshiyuki Kubo; Akira Tsuji
L-type fatty acid binding protein transgenic mouse as a novel tool to explore cytotoxicity to renal proximal tubules.
Drug metabolism and pharmacokinetics 2008;23(4):271-8.
2008: Kengo Furuichi; Takashi Wada; Shinji Kitajikma; Tadasi Toyama; Toshiya Okumura; Akinori Hara; Hiroshi Kawachi; Fujio Shimizu; takeshi sugaya; Naofumi Mukaida; Shosaku Narumi; Kouji Matsushima; Shuichi Kaneko
IFN-inducible protein 10 (CXCL10) regulates tubular cell proliferation in renal ischemia-reperfusion injury.
Nephron. Experimental nephrology 2008;109(1):c29-38.
2007: Rie Yamamoto; Hiroshi Akazawa; Kaoru Ito; Haruhiro Toko; Masanori Sano; Noritaka Yasuda; Yingjie Qin; Yoko Kudo; takeshi sugaya; Kenneth R Chien; Issei Komuro
Angiotensin II type 1a receptor signals are involved in the progression of heart failure in MLP-deficient mice.
Circulation journal : official journal of the Japanese Circulation Society 2007;71(12):1958-64.
2007: Tsukasa Nakamura; Teruo Inoue; takeshi sugaya; Yasuhiro Kawagoe; Tsukasa Suzuki; Yoshihiko Ueda; Hikaru Koide; Koichi Node
Beneficial effects of olmesartan and temocapril on urinary liver-type fatty acid-binding protein levels in normotensive patients with immunoglobin A nephropathy.
American journal of hypertension 2007;20(11):1195-201.
2007: Tokunori Yamamoto; Eisei Noiri; Yoshinari Ono; Kent Doi; Kousuke Negishi; Atsuko Kamijo; Kenjiro Kimura; Toshiro Fujita; Tsuneo Kinukawa; Hideki Taniguchi; Kazuo Nakamura; Momokazu Goto; Naoshi Shinozaki; Shinichi Ohshima; takeshi sugaya
Renal L-type fatty acid--binding protein in acute ischemic injury.
Journal of the American Society of Nephrology : JASN 2007;18(11):2894-902.
2007: Keiko Ohwada; K Watanabe; Kaori Okuyama; Y Ohkawara; takeshi sugaya; Motoaki Takayanagi; Isao Ohno
The involvement of type 1a angiotensin II receptors in the regulation of airway inflammation in a murine model of allergic asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(11):1720-7.
2007: Tsukasa Nakamura; takeshi sugaya; Yasuhiro Kawagoe; Tsukasa Suzuki; Yoshihiko Ueda; Hikaru Koide; Teruo Inoue; Koichi Node
Azelnidipine reduces urinary protein excretion and urinary liver-type fatty acid binding protein in patients with hypertensive chronic kidney disease.
The American journal of the medical sciences 2007;333(6):321-6.
2007: T Nakamura; takeshi sugaya; H Koide
Angiotensin II receptor antagonist reduces urinary liver-type fatty acid-binding protein levels in patients with diabetic nephropathy and chronic renal failure.
Diabetologia 2007;50(2):490-2.
2007: Izaya Nakaya; Takashi Wada; Kengo Furuichi; Norihiko Sakai; Kiyoki Kitagawa; Hitoshi Yokoyama; Yuko Ishida; Toshikazu Kondo; takeshi sugaya; Hiroshi Kawachi; Fujio Shimizu; Shosaku Narumi; Makoto Haino; Craig Gerard; Kouji Matsushima; Shuichi Kaneko
Blockade of IP-10/CXCR3 promotes progressive renal fibrosis.
Nephron. Experimental nephrology 2007;107(1):e12-21.
2006: Atsuko Kamijo-Ikemori; takeshi sugaya; Kenjiro Kimura
Urinary fatty acid binding protein in renal disease.
Clinica chimica acta; international journal of clinical chemistry 2006;374(1-2):1-7.
2006: Hirokazu Okada; Tsutomu Inoue; Tomohiro Kikuta; Yusuke Watanabe; Yoshihiko Kanno; Shinichi Ban; takeshi sugaya; Masatsugu Horiuchi; Hiromichi Suzuki
A possible anti-inflammatory role of angiotensin II type 2 receptor in immune-mediated glomerulonephritis during type 1 receptor blockade.
The American journal of pathology 2006;169(5):1577-89.
2006: Akihiko Kimura; Yuko Ishida; Takahito Hayashi; Takashi Wada; Hitoshi Yokoyama; takeshi sugaya; Naofumi Mukaida; Toshikazu Kondo
Interferon-gamma plays protective roles in sodium arsenite-induced renal injury by up-regulating intrarenal multidrug resistance-associated protein 1 expression.
The American journal of pathology 2006;169(4):1118-28.
2006: Atsuko Kamijo-Ikemori; takeshi sugaya; Ayako Obama; Junya Hiroi; Hiroshi Miura; Minoru Watanabe; Toshio Kumai; Ritsuko Ohtani-Kaneko; Kazuaki Hirata; Kenjiro Kimura
Liver-type fatty acid-binding protein attenuates renal injury induced by unilateral ureteral obstruction.
The American journal of pathology 2006;169(4):1107-17.
2006: Kengo Furuichi; Takashi Wada; Yasunori Iwata; Satoshi Kokubo; Akinori Hara; Junya Yamahana; takeshi sugaya; Yoichiro Iwakura; Kouji Matsushima; Masahide Asano; Hitoshi Yokoyama; Shuichi Kaneko
Interleukin-1-dependent sequential chemokine expression and inflammatory cell infiltration in ischemia-reperfusion injury.
Critical care medicine 2006;34(9):2447-55.
2006: Tsukasa Nakamura; takeshi sugaya; Yasuhiro Kawagoe; Yoshihiko Ueda; Hikaru Koide
Effect of pioglitazone on urinary liver-type fatty acid-binding protein concentrations in diabetes patients with microalbuminuria.
Diabetes/metabolism research and reviews 2006;22(5):385-9.
2006: Tsukasa Nakamura; takeshi sugaya; Hikaru Koide
Cigarette smoking affects urinary liver-type fatty acid-binding protein concentration in patients with early diabetic nephropathy.
Diabetes care 2006;29(7):1717.
2006: Atsuhiro Ichihara; Fumiaki Suzuki; Tsutomu Nakagawa; Yuki Kaneshiro; Tomoko Takemitsu; Mariyo Sakoda; A H M Nurun Nabi; Akira Nishiyama; takeshi sugaya; Matsuhiko Hayashi; Tadashi Inagami
Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice.
Journal of the American Society of Nephrology : JASN 2006;17(7):1950-61.
2006: Hirokazu Okada; Tomohiro Kikuta; Tsutomu Inoue; Yoshihiko Kanno; Shinichi Ban; takeshi sugaya; Masaharu Takigawa; Hiromichi Suzuki
Dexamethasone induces connective tissue growth factor expression in renal tubular epithelial cells in a mouse strain-specific manner.
The American journal of pathology 2006;168(3):737-47.
2006: Tsukasa Nakamura; takeshi sugaya; Koichi Node; Yoshihiko Ueda; Hikaru Koide
Urinary excretion of liver-type fatty acid-binding protein in contrast medium-induced nephropathy.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2006;47(3):439-44.
2006: Tsukasa Nakamura; takeshi sugaya; Yasuhiro Kawagoe; Tsukasa Suzuki; Yoshihiko Ueda; Hikaru Koide
Effect of erythropoietin on urinary liver-type fatty-acid-binding protein in patients with chronic renal failure and anemia.
American journal of nephrology 2006;26(3):276-80.
2006: Tsukasa Nakamura; takeshi sugaya; Yasuhiro Kawagoe; Tsukasa Suzuki; Teruo Inoue; Koichi Node
Effect of pitavastatin on urinary liver-type fatty-acid-binding protein in patients with nondiabetic mild chronic kidney disease.
American journal of nephrology 2006;26(1):82-6.
2006: Tsukasa Nakamura; takeshi sugaya; Yasuhiro Kawagoe; Yoshihiko Ueda; Shiwori Osada; Hikaru Koide
Urinary liver-type fatty acid-binding protein levels for differential diagnosis of idiopathic focal glomerulosclerosis and minor glomerular abnormalities and effect of low-density lipoprotein apheresis.
Clinical nephrology 2006;65(1):1-6.
2005: Hideki Kato; Junji Ishida; Shigehiko Imagawa; Tomoko Saito; Norio Suzuki; Toshiki Matsuoka; takeshi sugaya; Keiji Tanimoto; Takashi Yokoo; Osamu Ohneda; Fumihiro Sugiyama; Ken-ichi Yagami; Toshiro Fujita; Masayuki Yamamoto; Masaomi Nangaku; Akiyoshi Fukamizu
Enhanced erythropoiesis mediated by activation of the renin-angiotensin system via angiotensin II type 1a receptor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(14):2023-5.
2005: Tsukasa Nakamura; takeshi sugaya; Yasuhiro Kawagoe; Yoshihiko Ueda; Shiwori Osada; Hikaru Koide
Effect of pitavastatin on urinary liver-type fatty acid-binding protein levels in patients with early diabetic nephropathy.
Diabetes care 2005;28(11):2728-32.
2005: Tsukasa Nakamura; takeshi sugaya; Yasuhiro Kawagoe; Yoshihiko Ueda; Shiwori Osada; Hikaru Koide
Candesartan reduces urinary fatty acid-binding protein excretion in patients with autosomal dominant polycystic kidney disease.
The American journal of the medical sciences 2005;330(4):161-5.
2005: Tsukasa Nakamura; takeshi sugaya; Isao Ebihara; Hikaru Koide
Urinary liver-type fatty acid-binding protein: discrimination between IgA nephropathy and thin basement membrane nephropathy.
American journal of nephrology 2005;25(5):447-50.
2005: Chiaki Tanifuji; Yusuke Suzuki; Wong Mu Geot; Satoshi Horikoshi; takeshi sugaya; Marta Ruiz-Ortega; jesus egido; Yasuhiko Tomino
Reactive oxygen species-mediated signaling pathways in angiotensin II-induced MCP-1 expression of proximal tubular cells.
Antioxidants & redox signaling 2005;7(9-10):1261-8.
2005: Tomokazu Matsuura; Hiroo Kumagai; Hiroshi Onimaru; Akira Kawai; Kamon Iigaya; Toshiko Onami; Katsufumi Sakata; Naoki Oshima; takeshi sugaya; Takao Saruta
Electrophysiological properties of rostral ventrolateral medulla neurons in angiotensin II 1a receptor knockout mice.
Hypertension 2005;46(2):349-54.
2005: Hirokazu Tsukahara; takeshi sugaya; Kazuyo Hayakawa; Yukiko Mori; Masahiro Hiraoka; Atsuko Hata; Mitsufumi Mayumi
Quantification of L-type fatty acid binding protein in the urine of preterm neonates.
Early human development 2005;81(7):643-6.
2005: Tatsuya Kobayashi; Tsutomu Inoue; Hirokazu Okada; Tomohiro Kikuta; Yoshihiko Kanno; Takashi Nishida; Masaharu Takigawa; takeshi sugaya; Hiromichi Suzuki
Connective tissue growth factor mediates the profibrotic effects of transforming growth factor-beta produced by tubular epithelial cells in response to high glucose.
Clinical and experimental nephrology 2005;9(2):114-21.
2005: Taku Shimizu; Takayuki Oishi; Akane Omori; Akiko Sugiura; Keiko Hirota; Hisanori Aoyama; Tomoko Saito; takeshi sugaya; Yasuhiro Kon; James Douglas Engel; Akiyoshi Fukamizu; Keiji Tanimoto
Identification of cis-regulatory sequences in the human angiotensinogen gene by transgene coplacement and site-specific recombination.
Molecular and cellular biology 2005;25(8):2938-45.
2005: Takeshi Tsujino; Yoshiro Naito; Daizo Kawasaki; Satoshi Okuda; Tsuyoshi Sakoda; Yoshio Fujioka; takeshi sugaya; Mitsumasa Ohyanagi
Circadian expression of plasminogen activator inhibitor-1 in angiotensin II type 1a receptor knockout mice.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2005;27(2-3):159-68.
2005: Hirokazu Okada; Tomohiro Kikuta; Tatsuya Kobayashi; Tsutomu Inoue; Yoshihiko Kanno; Masaharu Takigawa; takeshi sugaya; Jeffrey Kopp; Hiromichi Suzuki
Connective tissue growth factor expressed in tubular epithelium plays a pivotal role in renal fibrogenesis.
Journal of the American Society of Nephrology : JASN 2005;16(1):133-43.
2004: Atsuko Kamijo; Kenjiro Kimura; takeshi sugaya
[Urinary excretion of liver type fatty acid binding protein (L-FABP)].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 11():123-5.
2004: Hirokazu Okada; Yusuke Watanabe; Tomohiro Kikuta; Tatsuya Kobayashi; Yoshihiko Kanno; takeshi sugaya; Hiromichi Suzuki
Bradykinin decreases plasminogen activator inhibitor-1 expression and facilitates matrix degradation in the renal tubulointerstitium under angiotensin-converting enzyme blockade.
Journal of the American Society of Nephrology : JASN 2004;15(9):2404-13.
2004: Yoshikuni Nagashio; Hiroshi Asaumi; Shiro Watanabe; Yoko Nomiyama; Masashi Taguchi; Mitsuo Tashiro; takeshi sugaya; Makoto Otsuki
Angiotensin II type 1 receptor interaction is an important regulator for the development of pancreatic fibrosis in mice.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(1):G170-7.
2004: Junji Ishida; Tatsuo Hashimoto; Yasumi Hashimoto; Shiro Nishiwaki; Taku Iguchi; Shuichi Harada; takeshi sugaya; Hitomi Matsuzaki; Rie Yamamoto; Naotaka Shiota; Hideki Okunishi; Minoru Kihara; Satoshi Umemura; Fumihiro Sugiyama; Ken-ichi Yagami; Yoshitoshi Kasuya; Naoki Mochizuki; Akiyoshi Fukamizu
Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo.
The Journal of biological chemistry 2004;279(25):26274-9.
2004: Vanesa Esteban; Oscar Lorenzo; Mónica Rupérez; Yusuke Suzuki; Sergio Mezzano; Julia Blanco; Matthias Kretzler; takeshi sugaya; jesus egido; Marta Ruiz-Ortega
Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction.
Journal of the American Society of Nephrology : JASN 2004;15(6):1514-29.
2004: Hirokazu Ohashi; Hitoshi Takagi; Hideyasu Oh; Kiyoshi Suzuma; Izumi Suzuma; Noriko Miyamoto; Akiyoshi Uemura; Daisuke Watanabe; Tomoaki Murakami; takeshi sugaya; Akiyoshi Fukamizu; Yoshihito Honda
Phosphatidylinositol 3-kinase/Akt regulates angiotensin II-induced inhibition of apoptosis in microvascular endothelial cells by governing survivin expression and suppression of caspase-3 activity.
Circulation research 2004;94(6):785-93.
2004: Haruhiro Toko; Yunzeng Zou; Tohru Minamino; Masanori Masaya; Mutsuo Harada; Toshio Nagai; takeshi sugaya; Fumio Terasaki; Yasushi Kitaura; Issei Komuro
Angiotensin II type 1a receptor is involved in cell infiltration, cytokine production, and neovascularization in infarcted myocardium.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(4):664-70.
2004: Hideaki Nakajima; Masaru Takenaka; Jun-Ya Kaimori; Takayuki Hamano; Hirotsugu Iwatani; takeshi sugaya; Takahito Ito; Masatsugu Hori; Enyu Imai
Activation of the signal transducer and activator of transcription signaling pathway in renal proximal tubular cells by albumin.
Journal of the American Society of Nephrology : JASN 2004;15(2):276-85.
2004: Kazuya Shinozaki; Kazuhide Ayajiki; Yoshihiko Nishio; takeshi sugaya; Atsunori Kashiwagi; Tomio Okamura
Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance.
Hypertension 2004;43(2):255-62.
2004: Tomoko Saito; Junji Ishida; Eriko Takimoto-Ohnishi; Shoko Takamine; Taku Shimizu; takeshi sugaya; Hideki Kato; Toshiki Matsuoka; Masaomi Nangaku; Yasuhiro Kon; Fumihiro Sugiyama; Ken-ichi Yagami; Akiyoshi Fukamizu
An essential role for angiotensin II type 1a receptor in pregnancy-associated hypertension with intrauterine growth retardation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(2):388-90.
2003: Mikio Kakishita; Kazufumi Nakamura; Masato Asanuma; Hiroshi Morita; Hironori Saito; Kengo Kusano; Yoichi Nakamura; Tetsuro Emori; Hiromi Matsubara; takeshi sugaya; Norio Ogawa; Tohru Ohe
Direct evidence for increased hydroxyl radicals in angiotensin II-induced cardiac hypertrophy through angiotensin II type 1a receptor.
Journal of cardiovascular pharmacology 2003;42 Suppl 1():S67-70.
2003: Hirokazu Okada; Yusuke Watanabe; Tsutomu Inoue; Tatsuya Kobayashi; Yoshihiko Kanno; Goshi Shiota; Toshikazu Nakamura; takeshi sugaya; Akiyoshi Fukamizu; Hiromichi Suzuki
Transgene-derived hepatocyte growth factor attenuates reactive renal fibrosis in aristolochic acid nephrotoxicity.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(12):2515-23.
2003: Rui Chen; Masaru Iwai; Lan Wu; Jun Suzuki; Li-Juan Min; Tetsuya Shiuchi; takeshi sugaya; Hong-Wei Liu; Tai-Xing Cui; Masatsugu Horiuchi
Important role of nitric oxide in the effect of angiotensin-converting enzyme inhibitor imidapril on vascular injury.
Hypertension 2003;42(4):542-7.
2003: Jun-ya Kaimori; Masaru Takenaka; Hideaki Nakajima; Takayuki Hamano; Masaru Horio; takeshi sugaya; Takahito Ito; Masatsugu Hori; Kousaku Okubo; Enyu Imai
Induction of glia maturation factor-beta in proximal tubular cells leads to vulnerability to oxidative injury through the p38 pathway and changes in antioxidant enzyme activities.
The Journal of biological chemistry 2003;278(35):33519-27.
2003: Kimiyasu Egami; Toyoaki Murohara; Toshifumi Shimada; Ken-Ichiro Sasaki; Satoshi Shintani; takeshi sugaya; Masahiro Ishii; Teiji Akagi; Hisao Ikeda; Toyojiro Matsuishi; Tsutomu Imaizumi
Role of host angiotensin II type 1 receptor in tumor angiogenesis and growth.
The Journal of clinical investigation 2003;112(1):67-75.
2003: Kiho Takaya; Daisuke Koya; Motohide Isono; Toshiro Sugimoto; takeshi sugaya; Atsunori Kashiwagi; Masakazu Haneda
Involvement of ERK pathway in albumin-induced MCP-1 expression in mouse proximal tubular cells.
American journal of physiology. Renal physiology 2003;284(5):F1037-45.
2003: Hidenori Hattori; Mamoru Shibata; takeshi sugaya; Junichi Hamada; Yasuo Fukuuchi
Delayed phosphorylation of p38 mitogen-activated protein kinase in the AT1a knock-out mouse striatal neurons during middle cerebral artery occlusion and reperfusion.
Neuroscience letters 2003;341(1):9-12.
2003: Keiko Hirota; Hiroaki Daitoku; Hitomi Matsuzaki; Natsumi Araya; Kazuyuki Yamagata; Sachie Asada; takeshi sugaya; Akiyoshi Fukamizu
Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor.
The Journal of biological chemistry 2003;278(15):13056-60.
2002: Atsuhiro Ichihara; Matsuhiko Hayashi; Yukako Koura; Yuko Tada; takeshi sugaya; Nobuhisa Hirota; Takao Saruta
Blunted tubuloglomerular feedback by absence of angiotensin type 1A receptor involves neuronal NOS.
Hypertension 2002;40(6):934-9.
2002: Yusuke Suzuki; Carmen Gómez-Guerrero; Isao Shirato; Oscar López-Franco; Purificación Hernández-Vargas; Guillermo Sanjuán; Marta Ruiz-Ortega; takeshi sugaya; Ko Okumura; Yasuhiko Tomino; Chisei Ra; jesus egido
Susceptibility to T cell-mediated injury in immune complex disease is linked to local activation of renin-angiotensin system: the role of NF-AT pathway.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4136-46.
2002: Jun Suzuki; Masaru Iwai; Hironori Nakagami; Lan Wu; Rui Chen; takeshi sugaya; Mareomi Hamada; Kunio Hiwada; Masatsugu Horiuchi
Role of angiotensin II-regulated apoptosis through distinct AT1 and AT2 receptors in neointimal formation.
Circulation 2002;106(7):847-53.
2002: Haruhiro Toko; Toru Oka; Yunzeng Zou; Masaya Sakamoto; Miho Mizukami; Masanori Sano; Rie Yamamoto; takeshi sugaya; Issei Komuro
Angiotensin II type 1a receptor mediates doxorubicin-induced cardiomyopathy.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(4):597-603.
2002: Oscar Lorenzo; Marta Ruiz-Ortega; Yusuke Suzuki; Mónica Rupérez; Vanesa Esteban; takeshi sugaya; jesus egido
Angiotensin III activates nuclear transcription factor-kappaB in cultured mesangial cells mainly via AT(2) receptors: studies with AT(1) receptor-knockout mice.
Journal of the American Society of Nephrology : JASN 2002;13(5):1162-71.
2002: Ken Sasaki; Toyoaki Murohara; Hisao Ikeda; takeshi sugaya; Toshifumi Shimada; Satoshi Shintani; Tsutomu Imaizumi
Evidence for the importance of angiotensin II type 1 receptor in ischemia-induced angiogenesis.
The Journal of clinical investigation 2002;109(5):603-11.
2001: Yusuke Suzuki; O Lopez-Franco; D Gomez-Garre; Nuria Tejera; Carmen Gomez-Guerrero; takeshi sugaya; R Bernal; Julia Blanco; Luis Ortega; jesus egido
Renal tubulointerstitial damage caused by persistent proteinuria is attenuated in AT1-deficient mice: role of endothelin-1.
The American journal of pathology 2001;159(5):1895-904.
2001: Y Hisada; takeshi sugaya; S Tanaka; Y Suzuki; C Ra; K Kimura; A Fukamizu
An essential role of angiotensin II receptor type 1a in recipient kidney, not in transplanted peripheral blood leukocytes, in progressive immune-mediated renal injury.
Laboratory investigation; a journal of technical methods and pathology 2001;81(9):1243-51.
2001: S Inokuchi; K Kimura; takeshi sugaya; K Inokuchi; K Murakami; T Sakai
Hyperplastic vascular smooth muscle cells of the intrarenal arteries in angiotensin II type 1a receptor null mutant mice.
Kidney international 2001;60(2):722-31.
2001: M Satoh; N Kashihara; Yasushi Yamasaki; K Maruyama; K Okamoto; Yohei Maeshima; Hitoshi Sugiyama; takeshi sugaya; K Murakami; Hirofumi Makino
Renal interstitial fibrosis is reduced in angiotensin II type 1a receptor-deficient mice.
Journal of the American Society of Nephrology : JASN 2001;12(2):317-25.
2000: Y Hisada; Hiroaki Sakurai; takeshi sugaya
Cell to cell interaction between mesangial cells and macrophages induces the expression of monocyte chemoattractant protein-1 through nuclear factor-kappaB activation.
Biochemical and biophysical research communications 2000;269(2):309-16.
1999: K Harada; takeshi sugaya; K Murakami; Yoshio Yazaki; Issei Komuro
Angiotensin II type 1A receptor knockout mice display less left ventricular remodeling and improved survival after myocardial infarction.
Circulation 1999;100(20):2093-9.
1999: Y Hisada; takeshi sugaya; M Yamanouchi; H Uchida; H Fujimura; Hiroaki Sakurai; A Fukamizu; K Murakami
Angiotensin II plays a pathogenic role in immune-mediated renal injury in mice.
The Journal of clinical investigation 1999;103(5):627-35.
1998: K Harada; Issei Komuro; Ichiro Shiojima; Doubun Hayashi; Sumiyo Kudoh; T Mizuno; K Kijima; H Matsubara; takeshi sugaya; K Murakami; Yoshio Yazaki
Pressure overload induces cardiac hypertrophy in angiotensin II type 1A receptor knockout mice.
Circulation 1998;97(19):1952-9.
1998: K Harada; Issei Komuro; Doubun Hayashi; takeshi sugaya; K Murakami; Yoshio Yazaki
Angiotensin II type 1a receptor is involved in the occurrence of reperfusion arrhythmias.
Circulation 1998;97(4):315-7.