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Thomas Cardillo

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TOP 3
Xiaochuan Chen; David V Gold; Thomas M Cardillo; Chien-Hsing Chang; Rhona Stein; David M Goldenberg
Prevention of acute graft-versus-host disease in a xenogeneic SCID mouse model by the humanized anti-CD74 antagonistic antibody milatuzumab.
Robert M Sharkey; Catharina M van Rij; Otto C Boerman; Thomas M Cardillo; Chien-Hsing Chang; Cathelijne Frielink; Habibe Karacay; William J McBride; Celeste Regino; Edmund A Rossi; David M Goldenberg
A new Tri-Fab bispecific antibody for pretargeting Trop-2-expressing epithelial cancers.
Pankaj Gupta; Natarajan Muthusamy; Edmund A Rossi; John C Byrd; Thomas M Cardillo; Richard R Furman; David M Goldenberg; Chien-Hsing Chang
Dual-targeting immunotherapy of lymphoma: potent cytotoxicity of anti-CD20/CD74 bispecific antibodies in mantle cell and other lymphomas.

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All Publications

2013: Xiaochuan Chen; David V Gold; Thomas M Cardillo; Chien-Hsing Chang; Rhona Stein; David M Goldenberg
Prevention of acute graft-versus-host disease in a xenogeneic SCID mouse model by the humanized anti-CD74 antagonistic antibody milatuzumab.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2013;19(1):28-39.
2012: Robert M Sharkey; Catharina M van Rij; Otto C Boerman; Thomas M Cardillo; Chien-Hsing Chang; Cathelijne Frielink; Habibe Karacay; William J McBride; Celeste Regino; Edmund A Rossi; David M Goldenberg
A new Tri-Fab bispecific antibody for pretargeting Trop-2-expressing epithelial cancers.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(10):1625-32.
2012: Pankaj Gupta; Natarajan Muthusamy; Edmund A Rossi; John C Byrd; Thomas M Cardillo; Richard R Furman; David M Goldenberg; Chien-Hsing Chang
Dual-targeting immunotherapy of lymphoma: potent cytotoxicity of anti-CD20/CD74 bispecific antibodies in mantle cell and other lymphomas.
Blood 2012;119(16):3767-78.
2012: Chien-Hsing Chang; Tina Falkeborn; David M Goldenberg; Jorma Hinkula; Rongxiu Li; Meiyu Loo; Edmund A Rossi; Thomas M Cardillo; Britta Wahren
A novel class of anti-HIV agents with multiple copies of enfuvirtide enhances inhibition of viral replication and cellular transmission in vitro.
PloS one 2012;7(7):e41235.
2010: Rhona Stein; Pankaj Gupta; Xiaochuan Chen; Thomas M Cardillo; Richard R Furman; Susan Chen; Chien-Hsing Chang; David M Goldenberg
Therapy of B-cell malignancies by anti-HLA-DR humanized monoclonal antibody, IMMU-114, is mediated through hyperactivation of ERK and JNK MAP kinase signaling pathways.
Blood 2010;115(25):5180-90.
2009: Serengulam V Govindan; Thomas M Cardillo; Sung-Ju Moon; Hans J Hansen; David M Goldenberg
CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6052-61.
2009: David M Goldenberg; Edmund A Rossi; Rhona Stein; Thomas M Cardillo; Myron S Czuczman; Francisco J Hernandez-Ilizaliturri; Hans J Hansen; Chien-Hsing Chang
Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody.
Blood 2009;113(5):1062-70.
2008: Sung-Ju Moon; Serengulam V Govindan; Thomas M Cardillo; Christopher A D'Souza; Hans J Hansen; David M Goldenberg
Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy.
Journal of medicinal chemistry 2008;51(21):6916-26.
2008: David V Gold; David M Goldenberg; Habibe Karacay; Edmund A Rossi; Chien-Hsing Chang; Thomas M Cardillo; William J McBride; Robert M Sharkey
A novel bispecific, trivalent antibody construct for targeting pancreatic carcinoma.
Cancer research 2008;68(12):4819-26.
2007: Rhona Stein; M Jules Mattes; Thomas M Cardillo; Hans J Hansen; Chien-Hsing Chang; Jack Burton; Serengulam V Govindan; David M Goldenberg
CD74: a new candidate target for the immunotherapy of B-cell neoplasms.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(18 Pt 2):5556s-5563s.
2006: Dieter Moosmayer; Dietmar Berndorff; Chien-Hsing Chang; Robert M Sharkey; Axel Rother; Sandra Borkowski; Edmund A Rossi; William J McBride; Thomas M Cardillo; David M Goldenberg; Ludger M Dinkelborg
Bispecific antibody pretargeting of tumor neovasculature for improved systemic radiotherapy of solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(18):5587-95.
2006: Edmund A Rossi; David M Goldenberg; Thomas M Cardillo; William J McBride; Robert M Sharkey; Chien-Hsing Chang
Stably tethered multifunctional structures of defined composition made by the dock and lock method for use in cancer targeting.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(18):6841-6.
2006: David V Gold; David E Modrak; Zhiliang Ying; Thomas M Cardillo; Robert M Sharkey; David M Goldenberg
New MUC1 serum immunoassay differentiates pancreatic cancer from pancreatitis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(2):252-8.
2005: Robert M Sharkey; Thomas M Cardillo; Edmund A Rossi; Chien-Hsing Chang; Habibe Karacay; William J McBride; Hans J Hansen; Ivan D Horak; David M Goldenberg
Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody.
Nature medicine 2005;11(11):1250-5.
2005: Edmund A Rossi; Chien-Hsing Chang; Michele J Losman; Robert M Sharkey; Habibe Karacay; William McBride; Thomas M Cardillo; Hans J Hansen; Zhengxing Qu; Ivan D Horak; David M Goldenberg
Pretargeting of carcinoembryonic antigen-expressing cancers with a trivalent bispecific fusion protein produced in myeloma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(19 Pt 2):7122s-7129s.
2005: Robert M Sharkey; Habibe Karacay; Thomas M Cardillo; Chien-Hsing Chang; William J McBride; Edmund A Rossi; Ivan D Horak; David M Goldenberg
Improving the delivery of radionuclides for imaging and therapy of cancer using pretargeting methods.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(19 Pt 2):7109s-7121s.
2005: Puja Sapra; Rhona Stein; Jennifer Pickett; Zhengxing Qu; Serengulam V Govindan; Thomas M Cardillo; Hans J Hansen; Ivan D Horak; Gary L Griffiths; David M Goldenberg
Anti-CD74 antibody-doxorubicin conjugate, IMMU-110, in a human multiple myeloma xenograft and in monkeys.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(14):5257-64.
2005: David E Modrak; Habibe Karacay; Thomas M Cardillo; Guy Newsome; David M Goldenberg; David V Gold
Identification of a Mu-9 (anti-colon-specific antigen-p)-reactive peptide having homology to CA125 (MUC16).
International journal of oncology 2005;26(6):1591-6.
2004: Rhona Stein; Zhengxing Qu; Thomas M Cardillo; Susan Chen; Adriane Rosario; Ivan D Horak; Hans J Hansen; David M Goldenberg
Antiproliferative activity of a humanized anti-CD74 monoclonal antibody, hLL1, on B-cell malignancies.
Blood 2004;104(12):3705-11.
2004: David E Modrak; Thomas M Cardillo; Guy A Newsome; David M Goldenberg; David V Gold
Synergistic interaction between sphingomyelin and gemcitabine potentiates ceramide-mediated apoptosis in pancreatic cancer.
Cancer research 2004;64(22):8405-10.
2004: Jack D Burton; Scott Ely; Praveen K Reddy; Rhona Stein; David V Gold; Thomas M Cardillo; David M Goldenberg
CD74 is expressed by multiple myeloma and is a promising target for therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(19):6606-11.
2004: Thomas M Cardillo; Habibe Karacay; David M Goldenberg; Dion Yeldell; Chien-Hsing Chang; David E Modrak; Robert M Sharkey; David V Gold
Improved targeting of pancreatic cancer: experimental studies of a new bispecific antibody, pretargeting enhancement system for immunoscintigraphy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(10):3552-61.
2004: David V Gold; David E Modrak; Keith Schutsky; Thomas M Cardillo
Combined 90Yttrium-DOTA-labeled PAM4 antibody radioimmunotherapy and gemcitabine radiosensitization for the treatment of a human pancreatic cancer xenograft.
International journal of cancer. Journal international du cancer 2004;109(4):618-26.
2003: David V Gold; Keith Schutsky; David E Modrak; Thomas M Cardillo
Low-dose radioimmunotherapy ((90)Y-PAM4) combined with gemcitabine for the treatment of experimental pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 2):3929S-37S.
2003: P K Reddy; David V Gold; Thomas M Cardillo; David M Goldenberg; H Li; Jack D Burton
Interferon-gamma upregulates MUC1 expression in haematopoietic and epithelial cancer cell lines, an effect associated with MUC1 mRNA induction.
European journal of cancer (Oxford, England : 1990) 2003;39(3):397-404.
2002: Thomas M Cardillo; Rosalyn Blumenthal; Zhiliang Ying; David V Gold
Combined gemcitabine and radioimmunotherapy for the treatment of pancreatic cancer.
International journal of cancer. Journal international du cancer 2002;97(3):386-92.
2001: Thomas M Cardillo; Zhiliang Ying; David V Gold
Therapeutic advantage of (90)yttrium- versus (131)iodine-labeled PAM4 antibody in experimental pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(10):3186-92.
2001: David V Gold; Thomas M Cardillo; David M Goldenberg; Robert M Sharkey
Localization of pancreatic cancer with radiolabeled monoclonal antibody PAM4.
Critical reviews in oncology/hematology 2001;39(1-2):147-54.
2001: David V Gold; Thomas M Cardillo
Monoclonal antibody G47 engineered to be reactive with colorectal tumor mucin.
Hybridoma and hybridomics 2001;20(5-6):343-50.
1999: Jack Burton; D Mishina; Thomas M Cardillo; K Lew; A Rubin; David M Goldenberg; David V Gold
Epithelial mucin-1 (MUC1) expression and MA5 anti-MUC1 monoclonal antibody targeting in multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10 Suppl):3065s-3072s.
1997: David V Gold; Thomas M Cardillo; Y Vardi; R Blumenthal
Radioimmunotherapy of experimental pancreatic cancer with 131I-labeled monoclonal antibody PAM4.
International journal of cancer. Journal international du cancer 1997;71(4):660-7.
1994: David V Gold; K Lew; R Maliniak; M Hernandez; Thomas M Cardillo
Characterization of monoclonal antibody PAM4 reactive with a pancreatic cancer mucin.
International journal of cancer. Journal international du cancer 1994;57(2):204-10.

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