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Alastair Cardno

Research Profile

Disorders

Physiology

Activities & Behaviors

Schizophrenic Psychology

Genes & Molecular Sequences

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Great Britain

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Monozygotic Twins

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Publications

TOP 3
Marian Hamshere; Peter Holmans; Lisa A Jones; Geraldine M McCarthy; Peter McGuffin; Kieran C Murphy; Nadine Norton; Michael C O'Donovan; Michael J Owen; Robert D Sanders; Hywel J Williams; Nigel M Williams; Stanley Zammit; Nicholas Craddock; MY Gray; Alastair G Cardno
Phenotype evaluation and genomewide linkage study of clinical variables in schizophrenia.
Frühling Rijsdijk; Irving GOTTESMAN; Peter McGuffin; Alastair G Cardno
Heritability estimates for psychotic symptom dimensions in twins with psychotic disorders.
Charlotte L Allan; Alastair G Cardno; Frühling V Rijsdijk; Sridevi Kalidindi; Anne Farmer; Robin M Murray; Peter McGuffin
Twin study of illness history variables in psychosis.

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All Publications

2011: Marian Hamshere; Peter Holmans; Lisa A Jones; Geraldine M McCarthy; Peter McGuffin; Kieran C Murphy; Nadine Norton; Michael C O'Donovan; Michael J Owen; Robert D Sanders; Hywel J Williams; Nigel M Williams; Stanley Zammit; Nicholas Craddock; MY Gray; Alastair G Cardno
Phenotype evaluation and genomewide linkage study of clinical variables in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(8):929-40.
2011: Frühling Rijsdijk; Irving GOTTESMAN; Peter McGuffin; Alastair G Cardno
Heritability estimates for psychotic symptom dimensions in twins with psychotic disorders.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(1):89-98.
2009: Charlotte L Allan; Alastair G Cardno; Frühling V Rijsdijk; Sridevi Kalidindi; Anne Farmer; Robin M Murray; Peter McGuffin
Twin study of illness history variables in psychosis.
Schizophrenia research 2009;115(2-3):237-44.
2008: Alastair G Cardno; Frühling V Rijsdijk; Robin M Murray; Peter McGuffin
Twin study refining psychotic symptom dimensions as phenotypes for genetic research.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(7):1213-21.
2008: Charlotte L Allan; Alastair G Cardno; Peter McGuffin
Schizophrenia: from genes to phenes to disease.
Current psychiatry reports 2008;10(4):339-43.
2006: Marian Hamshere; Nigel M Williams; Nadine Norton; Hywel Williams; Alastair G Cardno; Stanley Zammit; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; G McCarthy; MY Gray; G Jones; Peter Holmans; Michael C O'Donovan; Michael J Owen; Nick Craddock
Genome wide significant linkage in schizophrenia conditioning on occurrence of depressive episodes.
Journal of medical genetics 2006;43(7):563-7.
2006: Nigel M Williams; Elaine K Green; Stuart Macgregor; Sarah Dwyer; Nadine Norton; Hywel Williams; Rachel Raybould; Detelina Grozeva; Marian Hamshere; Stanley Zammit; Lisa Jones; Alastair G Cardno; George Kirov; Ian Jones; Michael C O'Donovan; Michael J Owen; Nick Craddock
Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder.
Archives of general psychiatry 2006;63(4):366-73.
2006: Alastair G Cardno; Peter McGuffin
Genetics and delusional disorder.
Behavioral sciences & the law 2006;24(3):257-76.
2005: Marian Hamshere; Philip Bennett; Nigel Williams; Ricardo Segurado; Alastair G Cardno; Nadine Norton; David Lambert; Hywel Williams; George Kirov; Aiden Corvin; Peter Holmans; Lisa Jones; Ian Jones; Michael Gill; Michael C O'Donovan; Michael J Owen; Nick Craddock
Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13.
Archives of general psychiatry 2005;62(10):1081-8.
2004: Stanley Zammit; Gaynor Jones; Susan J Jones; Nadine Norton; Robert D Sanders; Charis Milham; Geraldine M McCarthy; Lisa Anne Jones; Alastair G Cardno; Marion Gray; Kieran C Murphy; Michael C O'Donovan; Michael J Owen
Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;128B(1):19-20.
2003: Nigel M Williams; Nadine Norton; Hywel Williams; Birgit Ekholm; Marian Hamshere; Y Lindblom; Kodavali V Chowdari; Alastair G Cardno; Stanley Zammit; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; G McCarthy; MY Gray; G Jones; Peter Holmans; Vishwajit L Nimgaonkar; R Adolfson; Urban Osby; L Terenius; Göran C Sedvall; Michael C O'Donovan; Michael J Owen
A systematic genomewide linkage study in 353 sib pairs with schizophrenia.
American journal of human genetics 2003;73(6):1355-67.
2003: C Whitehead; S Moss; Alastair G Cardno; Glyn Lewis
Antidepressants for the treatment of depression in people with schizophrenia: a systematic review.
Psychological medicine 2003;33(4):589-99.
2003: Peter McGuffin; Frühling Rijsdijk; Martin Andrew; Pak Sham; Randy Katz; Alastair G Cardno
The heritability of bipolar affective disorder and the genetic relationship to unipolar depression.
Archives of general psychiatry 2003;60(5):497-502.
2002: Alastair G Cardno; Frühling Rijsdijk; Pak C Sham; Robin M Murray; Peter McGuffin
A twin study of genetic relationships between psychotic symptoms.
The American journal of psychiatry 2002;159(4):539-45.
2002: Alastair G Cardno; Katherine Thomas; Peter McGuffin
Clinical variables and genetic loading for schizophrenia: analysis of published Danish adoption study data.
Schizophrenia bulletin 2002;28(3):393-9.
2002: Nigel M Williams; Gillian Spurlock; Nadine Norton; Hywel J Williams; Marian Hamshere; Michael Krawczak; George Kirov; Ivan Nikolov; Lyudmila Georgieva; Sue Jones; Alastair G Cardno; Michael C O'Donovan; Michael J Owen
Mutation screening and LD mapping in the VCFS deleted region of chromosome 22q11 in schizophrenia using a novel DNA pooling approach.
Molecular psychiatry 2002;7(10):1092-100.
2002: R J Anney; Mark I Rees; E Bryan; Gillian Spurlock; Nigel Williams; Nadine Norton; Hywel Williams; Alastair G Cardno; Stanley Zammit; Sue Jones; G Jones; Bastiaan Hoogendoorn; Kaye Smith; Marian Hamshere; S Coleman; Carol Guy; Michael C O'Donovan; Michael J Owen; Paul R Buckland
Characterisation, mutation detection, and association analysis of alternative promoters and 5' UTRs of the human dopamine D3 receptor gene in schizophrenia.
Molecular psychiatry 2002;7(5):493-502.
2002: C Whitehead; S Moss; Alastair G Cardno; G Lewis
Antidepressants for people with both schizophrenia and depression.
Cochrane database of systematic reviews (Online) 2002;(2):CD002305.
2002: E O'Mahony; Aiden Corvin; R O'Connell; C Comerford; B Larsen; R Jones; Fiona McCandless; George Kirov; Alastair G Cardno; Nick Craddock; Michael Gill
Sibling pairs with affective disorders: resemblance of demographic and clinical features.
Psychological medicine 2002;32(1):55-61.
2002: Alastair G Cardno; Pak C Sham; Anne E Farmer; Robin M Murray; Peter McGuffin
Heritability of Schneider's first-rank symptoms.
The British journal of psychiatry : the journal of mental science 2002;180():35-8.
2001: Gaynor Jones; Stanley Zammit; Nadine Norton; Marian Hamshere; S J Jones; Charis Milham; Robert D Sanders; Geraldine M McCarthy; Lisa Anne Jones; Alastair G Cardno; Marion Gray; Kieran C Murphy; Michael J Owen
Aggressive behaviour in patients with schizophrenia is associated with catechol-O-methyltransferase genotype.
The British journal of psychiatry : the journal of mental science 2001;179():351-5.
2001: Alastair G Cardno; Peter Holmans; Mark I Rees; Lisa Anne Jones; Geraldine M McCarthy; Marian Hamshere; Nigel M Williams; Nadine Norton; Hywel J Williams; Iain Fenton; Kieran C Murphy; Robert D Sanders; MY Gray; Michael C O'Donovan; Peter McGuffin; Michael J Owen
A genomewide linkage study of age at onset in schizophrenia.
American journal of medical genetics 2001;105(5):439-45.
2001: Alastair G Cardno; Pak C Sham; Robin M Murray; Peter McGuffin
Twin study of symptom dimensions in psychoses.
The British journal of psychiatry : the journal of mental science 2001;179():39-45.
2001: Pamela Sklar; Sibylle G Schwab; Nigel M Williams; Mark J Daly; Stephen F Schaffner; W Maier; Margot Albus; Mátyás Trixler; P Eichhammer; Bernard Lerer; Joachim Hallmayer; Nadine Norton; H Williams; Stanley Zammit; Alastair G Cardno; S Jones; G McCarthy; vihra milanova; George Kirov; M C O'Donovan; Eric S Lander; Michael J Owen; Dieter B Wildenauer
Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls.
Nature genetics 2001;28(2):126-8.
2001: Timothy Bowen; N Williams; Nadine Norton; Gillian Spurlock; Oliver H Wittekindt; Deborah J Morris-Rosendahl; Hywel Williams; L Brzustowicz; Bastiaan Hoogendoorn; Stanley Zammit; G Jones; Robert D Sanders; Lisa Anne Jones; G McCarthy; S Jones; A Bassett; Alastair G Cardno; Michael J Owen; Michael C O'Donovan
Mutation screening of the KCNN3 gene reveals a rare frameshift mutation.
Molecular psychiatry 2001;6(3):259-60.
2001: Lisa Anne Jones; Alastair G Cardno; Robert D Sanders; Michael J Owen; J Williams
Sustained and selective attention as measures of genetic liability to schizophrenia.
Schizophrenia research 2001;48(2-3):263-72.
2000: Lisa Anne Jones; Alastair G Cardno; Kieran C Murphy; Robert D Sanders; MY Gray; G McCarthy; Peter McGuffin; Michael J Owen; J Williams
The kings schizotypy questionnaire as a quantitative measure of schizophrenia liability.
Schizophrenia research 2000;45(3):213-21.
2000: J Austin; Paul R Buckland; Alastair G Cardno; Nigel Williams; Gillian Spurlock; Bastiaan Hoogendoorn; Stanley Zammit; G Jones; R Sanders; Lesley Jones; G McCarthy; Sue Jones; Nicholas J Bray; Peter McGuffin; Michael J Owen; Michael C O'Donovan
The high affinity neurotensin receptor gene (NTSR1): comparative sequencing and association studies in schizophrenia.
Molecular psychiatry 2000;5(5):552-7.
2000: Nicholas J Bray; Nigel M Williams; Timothy Bowen; Alastair G Cardno; Marion Gray; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; Gillian Spurlock; M C Odonovan; Michael J Owen
No evidence for association between a non-synonymous polymorphism in the gene encoding human metabotropic glutamate receptor 7 and schizophrenia.
Psychiatric genetics 2000;10(2):83-6.
2000: G Speight; Darko Turic; J Austin; Bastiaan Hoogendoorn; Alastair G Cardno; Lesley Jones; Kieran C Murphy; R Sanders; G McCarthy; Ian Jones; Fiona McCandless; Peter McGuffin; Nick Craddock; Michael J Owen; Paul R Buckland; Michael C O'Donovan
Comparative sequencing and association studies of aromatic L-amino acid decarboxylase in schizophrenia and bipolar disorder.
Molecular psychiatry 2000;5(3):327-31.
2000: Timothy Bowen; Carol A Guy; Alastair G Cardno; John B Vincent; James L Kennedy; Lisa Anne Jones; Marion Gray; Robert D Sanders; G McCarthy; Kieran C Murphy; Michael J Owen; Michael C O'Donovan
Repeat sizes at CAG/CTG loci CTG18.1, ERDA1 and TGC13-7a in schizophrenia.
Psychiatric genetics 2000;10(1):33-7.
2000: J Austin; Bastiaan Hoogendoorn; Paul R Buckland; G Speight; Alastair G Cardno; Timothy Bowen; Nigel Williams; Gillian Spurlock; R Sanders; Lesley Jones; K Murphy; G McCarthy; Peter McGuffin; Michael J Owen; Michael C O'Donovan
Comparative sequencing of the proneurotensin gene and association studies in schizophrenia.
Molecular psychiatry 2000;5(2):208-12.
2000: Alastair G Cardno; Irving Gottesman
Twin studies of schizophrenia: from bow-and-arrow concordances to star wars Mx and functional genomics.
American journal of medical genetics 2000;97(1):12-7.
2000: Michael J Owen; Alastair G Cardno; Michael C O'Donovan
Psychiatric genetics: back to the future.
Molecular psychiatry 2000;5(1):22-31.
1999: Hywel J Williams; Nicholas J Bray; Kieran C Murphy; Alastair G Cardno; Lisa Anne Jones; Michael J Owen
No evidence for allelic association between schizophrenia and a functional variant of the human dopamine beta-hydroxylase gene (DBH).
American journal of medical genetics 1999;88(5):557-9.
1999: Nigel M Williams; Mark I Rees; Peter Holmans; Nadine Norton; Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; G McCarthy; MY Gray; Iain Fenton; Peter McGuffin; Michael J Owen
A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs.
Human molecular genetics 1999;8(9):1729-39.
1999: Mark I Rees; Iain Fenton; Nigel M Williams; Peter Holmans; Nadine Norton; Alastair G Cardno; Philip Asherson; Gillian Spurlock; E Roberts; E Parfitt; R Mant; Homero Vallada; E Dawson; M W Li; DA Collier; John F Powell; S Nanko; Michael Gill; Peter McGuffin; Michael J Owen
Autosome search for schizophrenia susceptibility genes in multiply affected families.
Molecular psychiatry 1999;4(4):353-9.
1999: Michael J Owen; Alastair G Cardno
Psychiatric genetics: progress, problems, and potential.
Lancet 1999;354 Suppl 1():SI11-4.
1999: Alastair G Cardno; Timothy Bowen; Carol A Guy; Lisa Anne Jones; G McCarthy; Nigel M Williams; Kieran C Murphy; Gillian Spurlock; Marion Gray; Robert D Sanders; Nick Craddock; Peter McGuffin; Michael J Owen; Michael C O'Donovan
CAG repeat length in the hKCa3 gene and symptom dimensions in schizophrenia.
Biological psychiatry 1999;45(12):1592-6.
1999: Alastair G Cardno; E J Marshall; B Coid; A M Macdonald; T R Ribchester; N J Davies; P Venturi; Lisa Anne Jones; Shon Lewis; Pak C Sham; Irving Gottesman; Anne E Farmer; Peter McGuffin; A M Reveley; Robin M Murray
Heritability estimates for psychotic disorders: the Maudsley twin psychosis series.
Archives of general psychiatry 1999;56(2):162-8.
1999: Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; Philip Asherson; Michael J Owen; Peter McGuffin
Dimensions of psychosis in affected sibling pairs.
Schizophrenia bulletin 1999;25(4):841-50.
1998: Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; Philip Asherson; Michael J Owen; Peter McGuffin
Sibling pairs with schizophrenia or schizoaffective disorder: associations of subtypes, symptoms and demographic variables.
Psychological medicine 1998;28(4):815-23.
1998: Philip Asherson; R Mant; Nigel Williams; Alastair G Cardno; Lesley Jones; K Murphy; DA Collier; S Nanko; Nick Craddock; S Morris; Walter Muir; B Blackwood; Peter McGuffin; Michael J Owen
A study of chromosome 4p markers and dopamine D5 receptor gene in schizophrenia and bipolar disorder.
Molecular psychiatry 1998;3(4):310-20.
1998: Timothy Bowen; Carol A Guy; Nick Craddock; Alastair G Cardno; Nigel M Williams; Gillian Spurlock; Kieran C Murphy; Lisa Anne Jones; Marion Gray; Robert D Sanders; G McCarthy; K George Chandy; Emmanuelle Fantino; Katalin Kalman; George A Gutman; J Jay Gargus; Julie Williams; Peter McGuffin; Michael J Owen; Michael C O'Donovan
Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia.
Molecular psychiatry 1998;3(3):266-9.
1998: Julie Williams; Gillian Spurlock; Peter Holmans; R Mant; K Murphy; Lesley Jones; Alastair G Cardno; Philip Asherson; D H R Blackwood; Walter Muir; Kurt Meszaros; Harald N Aschauer; J Mallet; C Laurent; P Pekkarinen; J Seppala; Costas N Stefanis; George N Papadimitriou; Fabio Macciardi; M Verga; C Pato; H Azevedo; M A Crocq; Hugh M D Gurling; Michael J Owen
A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia.
Molecular psychiatry 1998;3(2):141-9.
1998: Alastair G Cardno; Kieran C Murphy; Lisa Anne Jones; A M Cobb; Jonathon Gray; Peter McGuffin; Michael J Owen
Polydactyly and psychosis. Five cases of co-occurrence.
The British journal of psychiatry : the journal of mental science 1998;172():184-5.
1998: Alastair G Cardno; Fiona McCandless; Timothy Bowen; Carol A Guy; Lisa Anne Jones; Kieran C Murphy; Peter McGuffin; Michael J Owen; Nick Craddock; Michael C O'Donovan
Association between functional psychosis and expanded CAG/CTG repeats is not explained by health stratification.
Psychiatric genetics 1998;8(1):29-32.
1998: Timothy Bowen; Nadine Norton; NJ Jacobsen; Carol Guy; johanna k macpherson; Robert D Sanders; Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Peter McGuffin; Nick Craddock; Michael C O'Donovan; Michael J Owen
Linked polymorphisms upstream of exons 1 and 2 of the human cholecystokinin gene are not associated with schizophrenia or bipolar disorder.
Molecular psychiatry 1998;3(1):67-71.
1998: Gillian Spurlock; A Heils; Peter Holmans; Julie Williams; UM D'Souza; Alastair G Cardno; Kieran C Murphy; Lesley Jones; Paul R Buckland; Peter McGuffin; K P Lesch; Michael J Owen
A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter.
Molecular psychiatry 1998;3(1):42-9.
1997: johanna k macpherson; Gillian Spurlock; Nigel M Williams; Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Philip Asherson; Peter Holmans; Iain Fenton; Peter McGuffin; Michael J Owen
Linkage study of chromosome 6p in sib-pairs with schizophrenia.
American journal of medical genetics 1997;74(3):319-23.
1997: Alastair G Cardno; Peter Holmans; I Harvey; M B Williams; Michael J Owen; Peter McGuffin
Factor-derived subsyndromes of schizophrenia and familial morbid risks.
Schizophrenia research 1997;23(3):231-8.
1997: Nigel M Williams; Lisa Anne Jones; Kieran C Murphy; Alastair G Cardno; Philip Asherson; Julie Williams; Peter McGuffin; Michael J Owen
No evidence for an allelic association between schizophrenia and markers D22S278 and D22S283.
American journal of medical genetics 1997;74(1):37-9.
1997: Nigel M Williams; Alastair G Cardno; Kieran C Murphy; Lisa Anne Jones; Philip Asherson; Peter McGuffin; Michael J Owen
Association between schizophrenia and a microsatellite polymorphism at the dopamine D5 receptor gene.
Psychiatric genetics 1997;7(2):83-5.
1996: Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Philip Asherson; L C Scott; J Williams; Michael J Owen; Peter McGuffin
Factor analysis of schizophrenic symptoms using the OPCRIT checklist.
Schizophrenia research 1996;22(3):233-9.
1996: Alastair G Cardno; Kieran C Murphy; Lisa Anne Jones; Carol A Guy; Philip Asherson; M H De Azevedo; Isabel Coelho; A J de Macedo e Santos; C N Pato; Peter McGuffin; Michael J Owen; Michael C O'Donovan
Expanded CAG/CTG repeats in schizophrenia. A study of clinical correlates.
The British journal of psychiatry : the journal of mental science 1996;169(6):766-71.
1996: Timothy Bowen; Carol Guy; G Speight; L Jones; Alastair G Cardno; K Murphy; Peter McGuffin; Michael J Owen; Michael C O'Donovan
Expansion of 50 CAG/CTG repeats excluded in schizophrenia by application of a highly efficient approach using repeat expansion detection and a PCR screening set.
American journal of human genetics 1996;59(4):912-7.
1996: Philip Asherson; R Mant; Peter Holmans; Julie Williams; Alastair G Cardno; K Murphy; Lesley Jones; David Collier; Peter McGuffin; Michael J Owen
Linkage, association and mutational analysis of the dopamine D3 receptor gene in schizophrenia.
Molecular psychiatry 1996;1(2):125-32.
1996: johanna k macpherson; Nigel M Williams; Julie Williams; Lisa Anne Jones; Alastair G Cardno; Kieran C Murphy; Gillian Spurlock; B Riley; P Scambler; Philip Asherson; Peter McGuffin; Michael J Owen
No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol O-methyltransferase activity.
The American journal of psychiatry 1996;153(2):268-70.
1996: Kieran C Murphy; Alastair G Cardno; Peter McGuffin
The molecular genetics of schizophrenia.
Journal of molecular neuroscience : MN 1996;7(2):147-57.
1995: Alastair G Cardno; A E Farmer
The case for or against heterogeneity in the etiology of schizophrenia. The genetic evidence.
Schizophrenia research 1995;17(2):153-9.
1995: Michael C O'Donovan; C Guy; N Craddock; Kieran C Murphy; Alastair G Cardno; L A Jones; Michael J Owen; Peter McGuffin
Expanded CAG repeats in schizophrenia and bipolar disorder.
Nature genetics 1995;10(4):380-1.
1994: Alastair G Cardno; Peter McGuffin
The molecular genetics of schizophrenia.
Neuropathology and applied neurobiology 1994;20(4):344-9.