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Lon Cardon

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Colin F Spraggs; Laura R Budde; Linda P Briley; Nan Bing; Charles J Cox; Karen S King; John C Whittaker; Vincent E Mooser; Alaknanda J Preston; Steven H Stein; Lon R Cardon
HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer.
Geraldine M Clarke; Carl A Anderson; Fredrik H Pettersson; Lon R Cardon; Andrew P Morris; Krina T Zondervan
Basic statistical analysis in genetic case-control studies.
Josine L Min; Andrew P Morris; Chris Newton-Cheh; Markus Perola; Fredrik H Pettersson; Jiannis Ragoussis; J Brent Richards; Nicole Soranzo; Tim D Spector; Ida Surakka; Gabriela L Surdulescu; Jennifer M Taylor; Tim Watts; Kourosh R Ahmadi; John Broxholme; Lon R Cardon; Christian Gieger; Cecilia M Lindgren; Ernesto Lowy; Krina T Zondervan
The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits.

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All Publications

2011: Colin F Spraggs; Laura R Budde; Linda P Briley; Nan Bing; Charles J Cox; Karen S King; John C Whittaker; Vincent E Mooser; Alaknanda J Preston; Steven H Stein; Lon R Cardon
HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(6):667-73.
2011: Geraldine M Clarke; Carl A Anderson; Fredrik H Pettersson; Lon R Cardon; Andrew P Morris; Krina T Zondervan
Basic statistical analysis in genetic case-control studies.
Nature protocols 2011;6(2):121-33.
2011: Josine L Min; Andrew P Morris; Chris Newton-Cheh; Markus Perola; Fredrik H Pettersson; Jiannis Ragoussis; J Brent Richards; Nicole Soranzo; Tim D Spector; Ida Surakka; Gabriela L Surdulescu; Jennifer M Taylor; Tim Watts; Kourosh R Ahmadi; John Broxholme; Lon R Cardon; Christian Gieger; Cecilia M Lindgren; Ernesto Lowy; Krina T Zondervan
The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits.
PloS one 2011;6(7):e22070.
2010: Carl A Anderson; Fredrik H Pettersson; Geraldine M Clarke; Lon R Cardon; Andrew P Morris; Krina T Zondervan
Data quality control in genetic case-control association studies.
Nature protocols 2010;5(9):1564-73.
2010: J R Fraser Cummings; R M Cooney; G Clarke; John Beckly; A Geremia; saad pathan; Laura Hancock; Changcun Guo; Lon R Cardon; Derek P Jewell
The genetics of NOD-like receptors in Crohn's disease.
Tissue antigens 2010;76(1):48-56.
2010: Francisco-Javier Gamo; Laura M Sanz; Jaume Vidal; Cristina de Cozar; Emilio Alvarez; Jose-Luis Lavandera; Dana E Vanderwall; Darren V S Green; Vinod Kumar; Samiul Hasan; James R Brown; Catherine E Peishoff; Lon R Cardon; Jose F Garcia-Bustos
Thousands of chemical starting points for antimalarial lead identification.
Nature 2010;465(7296):305-10.
2010: Joanna J Zhuang; Krina T Zondervan; Fredrik Nyberg; Chris Harbron; Ansar Jawaid; Lon R Cardon; Bryan J Barratt; Andrew P Morris
Optimizing the power of genome-wide association studies by using publicly available reference samples to expand the control group.
Genetic epidemiology 2010;34(4):319-26.
2010: Geraldine M Clarke; Lon R Cardon
Aspects of observing and claiming allele flips in association studies.
Genetic epidemiology 2010;34(3):266-74.
2009: Teri A Manolio; Francis S Collins; Nancy J Cox; David B Goldstein; Lucia A Hindorff; David J Hunter; Mark I McCarthy; Erin M Ramos; Lon R Cardon; Aravinda Chakravarti; Judy H Cho; Alan E Guttmacher; Augustine Kong; Leonid Kruglyak; Elaine Mardis; Charles N Rotimi; Montgomery Slatkin; David Valle; Alice S Whittemore; Michael Boehnke; Andrew G Clark; Evan E Eichler; Greg Gibson; Jonathan L Haines; Trudy F C Mackay; Steven A McCarroll; Peter M Visscher
Finding the missing heritability of complex diseases.
Nature 2009;461(7265):747-53.
2009: D Brocklebank; Javier Gayán; J M Andresen; S A Roberts; Anne B Young; S R Snodgrass; J B Penney; M A Ramos-Arroyo; J J Cha; H D Rosas; Steven M Hersch; A Feigin; Stacey Cherny; N S Wexler; David E Housman; Lon R Cardon
Repeat instability in the 27-39 CAG range of the HD gene in the Venezuelan kindreds: Counseling implications.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(3):425-9.
2009: Robert Lawrence; Aaron G Day-Williams; Richard Mott; John Broxholme; Lon R Cardon; Eleftheria Zeggini
GLIDERS--a web-based search engine for genome-wide linkage disequilibrium between HapMap SNPs.
BMC bioinformatics 2009;10():367.
2009: Fredrik H Pettersson; Carl A Anderson; Geraldine M Clarke; Jeffrey C Barrett; Lon R Cardon; Andrew P Morris; Krina T Zondervan
Marker selection for genetic case-control association studies.
Nature protocols 2009;4(5):743-52.
2008: Simon Heath; Ivo Gut; Paul Brennan; James D McKay; Vladimir Bencko; Eleonora Fabianova; Lenka Foretova; Michael Georges; vladimir janout; Michael Kabesch; Hans E Krokan; Maiken B Elvestad; Jolanta Lissowska; Dana Mates; Peter Rudnai; Frank Skorpen; Stefan Schreiber; José M Soria; Ann-Christine Syvänen; Pierre Meneton; Serge Herçberg; Pilar Galan; Neonilia Szeszenia-Dabrowska; David Zaridze; Emmanuel Génin; Lon R Cardon; Mark Lathrop
Investigation of the fine structure of European populations with applications to disease association studies.
European journal of human genetics : EJHG 2008;16(12):1413-29.
2008: Carl A Anderson; Fredrik H Pettersson; Jeffrey C Barrett; Joanna J Zhuang; Jiannis Ragoussis; Lon R Cardon; Andrew P Morris
Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms.
American journal of human genetics 2008;83(1):112-9.
2008: Javier Gayán; Denise Brocklebank; J Michael Andresen; Gorka Alkorta-Aranburu; M Zameel Cader; Simone A Roberts; Stacey Cherny; Nancy S Wexler; Lon R Cardon; David E Housman
Genomewide linkage scan reveals novel loci modifying age of onset of Huntington's disease in the Venezuelan HD kindreds.
Genetic epidemiology 2008;32(5):445-53.
2008: David M Evans; Jeffrey C Barrett; Lon R Cardon
To what extent do scans of non-synonymous SNPs complement denser genome-wide association studies?
European journal of human genetics : EJHG 2008;16(6):718-23.
2008: Linda M Dong; John D Potter; Emily White; Cornelia M Ulrich; Lon R Cardon; Ulrike Peters
Genetic susceptibility to cancer: the role of polymorphisms in candidate genes.
JAMA : the journal of the American Medical Association 2008;299(20):2423-36.
2008: Mark I McCarthy; Goncalo Abecasis; Lon R Cardon; David B Goldstein; Julian Little; John Ioannidis; Joel N Hirschhorn
Genome-wide association studies for complex traits: consensus, uncertainty and challenges.
Nature reviews. Genetics 2008;9(5):356-69.
2008: Xiayi Ke; Martin Taylor; Lon R Cardon
Singleton SNPs in the human genome and implications for genome-wide association studies.
European journal of human genetics : EJHG 2008;16(4):506-15.
2008: Fredrik Pettersson; Andrew P Morris; Michael R Barnes; Lon R Cardon
Goldsurfer2 (Gs2): a comprehensive tool for the analysis and visualization of genome wide association studies.
BMC bioinformatics 2008;9():138.
2007: Geraldine M Clarke; Kim Carter; Lyle Palmer; Andrew P Morris; Lon R Cardon
Fine mapping versus replication in whole-genome association studies.
American journal of human genetics 2007;81(5):995-1005.
2007: J R Fraser Cummings; Tariq Ahmad; Alessandra Geremia; John Beckly; Rachel Cooney; Laura Hancock; saad pathan; Changcun Guo; Lon R Cardon; Derek P Jewell
Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype.
Inflammatory bowel diseases 2007;13(9):1063-8.
2007: J R Fraser Cummings; Rachel Cooney; saad pathan; Carl A Anderson; Jeffrey C Barrett; John Beckly; Alessandra Geremia; Laura Hancock; Changcun Guo; Tariq Ahmad; Lon R Cardon; Derek P Jewell
Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene.
Inflammatory bowel diseases 2007;13(8):941-6.
2007: David A van Heel; Lude Franke; Karen A Hunt; Rhian Gwilliam; Alexandra Zhernakova; Mike Inouye; Martin C Wapenaar; M C N M Barnardo; Graeme Bethel; G K T Holmes; Conleth Feighery; Derek Jewell; Dermot Kelleher; Parveen Kumar; Simon Travis; Julian R F Walters; David S Sanders; Peter Howdle; Jill Swift; Raymond J Playford; William M McLaren; M Luisa Mearin; Chris J J Mulder; Ross McManus; Ralph McGinnis; Lon R Cardon; Panos Deloukas; Cisca Wijmenga
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.
Nature genetics 2007;39(7):827-9.
2007: Eleftheria Zeggini; Michael N Weedon; Cecilia M Lindgren; Timothy M Frayling; Katherine S Elliott; Hana Lango; Nicholas J Timpson; John R B Perry; Nigel W Rayner; Michael Weedon; Jeffrey C Barrett; Beverley Shields; Andrew P Morris; Sian Ellard; Christopher J Groves; Lorna W Harries; Jonathan Marchini; Katharine R Owen; Beatrice Knight; Lon R Cardon; Mark Walker; Graham A Hitman; Andrew D Morris; Alex S F Doney; Mark I McCarthy; Andrew T Hattersley
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
Science (New York, N.Y.) 2007;316(5829):1336-41.
2007: J Michael Andresen; Javier Gayán; Luc Djoussé; Simone Roberts; Denise Brocklebank; Stacey Cherny; Lon R Cardon; James Gusella; Marcy E MacDonald; Richard H Myers; David E Housman; Nancy S Wexler
The relationship between CAG repeat length and age of onset differs for Huntington's disease patients with juvenile onset or adult onset.
Annals of human genetics 2007;71(Pt 3):295-301.
2007: Krina T Zondervan; Susan A Treloar; Jianghai Lin; Daniel E Weeks; Dale R Nyholt; Jon Mangion; Ian J Mackay; Lon R Cardon; Nicholas G Martin; Stephen Kennedy; Grant W Montgomery
Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13-15.
Human reproduction (Oxford, England) 2007;22(3):717-28.
2007: Krina T Zondervan; Lon R Cardon
Designing candidate gene and genome-wide case-control association studies.
Nature protocols 2007;2(10):2492-501.
2007: J M Andresen; Javier Gayán; Stacey Cherny; D Brocklebank; G Alkorta-Aranburu; E A Addis; Lon R Cardon; David E Housman; Nancy S Wexler
Replication of twelve association studies for Huntington's disease residual age of onset in large Venezuelan kindreds.
Journal of medical genetics 2007;44(1):44-50.
2006: Lon R Cardon
Genetics. Delivering new disease genes.
Science (New York, N.Y.) 2006;314(5804):1403-5.
2006: David M Evans; Andrew P Morris; Lon R Cardon; P C Sham
A note on the power to detect transmission distortion in parent-child trios via the transmission disequilibrium test.
Behavior genetics 2006;36(6):947-50.
2006: Jon W Gregersen; Kamil R Kranc; Xiayi Ke; Pia Svendsen; Lars S Madsen; Allan Randrup Thomsen; Lon R Cardon; John I Bell; Lars Fugger
Functional epistasis on a common MHC haplotype associated with multiple sclerosis.
Nature 2006;443(7111):574-7.
2006: Dermot P B McGovern; Helen Butler; Tariq Ahmad; Marta Paolucci; David A van Heel; Kenichi Negoro; Pirro Hysi; Jiannis Ragoussis; S P L Travis; Lon R Cardon; Derek P Jewell
TUCAN (CARD8) genetic variants and inflammatory bowel disease.
Gastroenterology 2006;131(4):1190-6.
2006: David M Evans; Jonathan Marchini; Andrew P Morris; Lon R Cardon
Two-stage two-locus models in genome-wide association.
PLoS genetics 2006;2(9):e157.
2006: Yeon-Kyeong Yoo; Xiayi Ke; Sungwoo Hong; Hye-Yoon Jang; Kyunghee Park; Sook Kim; TaeJin Ahn; Yeun-Du Lee; Okryeol Song; Na-Young Rho; Moon Sue Lee; Yeon-Su Lee; Jaeheup Kim; Young J Kim; Jun-Mo Yang; Kyuyoung Song; Kuchan Kimm; Bruce Weir; Lon R Cardon; Jong-Eun Lee; Jung-Joo Hwang
Fine-scale map of encyclopedia of DNA elements regions in the Korean population.
Genetics 2006;174(1):491-7.
2006: David M Evans; Lon R Cardon
Genome-wide association: a promising start to a long race.
Trends in genetics : TIG 2006;22(7):350-4.
2006: Jeffrey C Barrett; Lon R Cardon
Evaluating coverage of genome-wide association studies.
Nature genetics 2006;38(6):659-62.
2006: Anna González-Neira; Xiayi Ke; Oscar Lao; Francesc Calafell; Arcadi Navarro; David Comas; Howard Cann; Suzannah Bumpstead; Jilur Ghori; Sarah Hunt; Panos Deloukas; Carl Bruder; Lon R Cardon; Jaume Bertranpetit
The portability of tagSNPs across populations: a worldwide survey.
Genome research 2006;16(3):323-30.
2005: Eleftheria Zeggini; William Rayner; Andrew P Morris; Andrew T Hattersley; Mark Walker; Graham A Hitman; Panos Deloukas; Lon R Cardon; Mark I McCarthy
An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets.
Nature genetics 2005;37(12):1320-2.
2005: Geraldine M Clarke; Lon R Cardon
Disentangling linkage disequilibrium and linkage from dense single-nucleotide polymorphism trio data.
Genetics 2005;171(4):2085-95.
2005: Robert Lawrence; David M Evans; Andrew P Morris; Xiayi Ke; Sarah Hunt; Marta Paolucci; Jiannis Ragoussis; Panos Deloukas; David Bentley; Lon R Cardon
Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants.
Genome research 2005;15(11):1503-10.
2005: Bruce S Weir; Lon R Cardon; Amy D Anderson; Dahlia M Nielsen; William G Hill
Measures of human population structure show heterogeneity among genomic regions.
Genome research 2005;15(11):1468-76.
2005: Lyle Palmer; Lon R Cardon
Shaking the tree: mapping complex disease genes with linkage disequilibrium.
Lancet 2005;366(9492):1223-34.
2005: Javier Gayán; Erik G Willcutt; Simon E Fisher; Clyde Francks; Lon R Cardon; Richard K Olson; Bruce F Pennington; Shelley D Smith; Anthony P Monaco; John C DeFries
Bivariate linkage scan for reading disability and attention-deficit/hyperactivity disorder localizes pleiotropic loci.
Journal of child psychology and psychiatry, and allied disciplines 2005;46(10):1045-56.
2005: Xiayi Ke; Marcos M Miretti; John Broxholme; Sarah Hunt; Stephan Beck; David R Bentley; Panos Deloukas; Lon R Cardon
A comparison of tagging methods and their tagging space.
Human molecular genetics 2005;14(18):2757-67.
2005: Robert W Lawrence; David M Evans; Lon R Cardon
Prospects and pitfalls in whole genome association studies.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2005;360(1460):1589-95.
2005: Jonathan Marchini; Peter Donnelly; Lon R Cardon
Genome-wide strategies for detecting multiple loci that influence complex diseases.
Nature genetics 2005;37(4):413-7.
2005: Marcos M Miretti; Emily C Walsh; Xiayi Ke; Marcos Delgado; Mark Griffiths; Sarah Hunt; Jonathan Morrison; Pamela Whittaker; Eric S Lander; Lon R Cardon; David R Bentley; John D Rioux; Stephan Beck; Panos Deloukas
A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms.
American journal of human genetics 2005;76(4):634-46.
2005: David M Evans; Lon R Cardon
A comparison of linkage disequilibrium patterns and estimated population recombination rates across multiple populations.
American journal of human genetics 2005;76(4):681-7.
2005: Krina T Zondervan; Lon R Cardon; Stephen Kennedy; Nicholas G Martin; Susan A Treloar
Multivariate genetic analysis of chronic pelvic pain and associated phenotypes.
Behavior genetics 2005;35(2):177-88.
2005: Steven Wiltshire; Andrew P Morris; Mark I McCarthy; Lon R Cardon
How useful is the fine-scale mapping of complex trait linkage peaks? Evaluating the impact of additional microsatellite genotyping on the posterior probability of linkage.
Genetic epidemiology 2005;28(1):1-10.
2004: David M Evans; Lon R Cardon; Andrew P Morris
Genotype prediction using a dense map of SNPs.
Genetic epidemiology 2004;27(4):375-84.
2004: Bruce S Weir; William G Hill; Lon R Cardon
Allelic association patterns for a dense SNP map.
Genetic epidemiology 2004;27(4):442-50.
2004: Clyde Francks; Silvia Paracchini; Shelley D Smith; Alexandra Richardson; Thomas Scerri; Lon R Cardon; Angela J Marlow; I Laurence MacPhie; Janet Walter; Bruce F Pennington; Simon E Fisher; Richard K Olson; John C DeFries; John Stein; Anthony P Monaco
A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States.
American journal of human genetics 2004;75(6):1046-58.
2004: Fredrik Pettersson; Oskar Jonsson; Lon R Cardon
GOLDsurfer: three dimensional display of linkage disequilibrium.
Bioinformatics (Oxford, England) 2004;20(17):3241-3.
2004: Xiayi Ke; Caroline Durrant; Andrew P Morris; Sarah Hunt; David R Bentley; Panos Deloukas; Lon R Cardon
Efficiency and consistency of haplotype tagging of dense SNP maps in multiple samples.
Human molecular genetics 2004;13(21):2557-65.
2004: David M Evans; Lon R Cardon
Guidelines for genotyping in genomewide linkage studies: single-nucleotide-polymorphism maps versus microsatellite maps.
American journal of human genetics 2004;75(4):687-92.
2004: Andrew Timms; Alison M Crane; Anne-Marie Sims; Heather J Cordell; Linda Bradbury; Aaron Abbott; Mark R E Coyne; Owen Beynon; Ibi Herzberg; Gordon W Duff; Andrei Calin; Lon R Cardon; B Paul Wordsworth; Matthew A Brown
The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis.
American journal of human genetics 2004;75(4):587-95.
2004: Caroline Durrant; Krina T Zondervan; Lon R Cardon; Sarah Hunt; Panos Deloukas; Andrew P Morris
Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes.
American journal of human genetics 2004;75(1):35-43.
2004: Jonathan Marchini; Lon R Cardon; Michael S Phillips; Peter Donnelly
The effects of human population structure on large genetic association studies.
Nature genetics 2004;36(5):512-7.
2004: Xiayi Ke; Sarah Hunt; William Tapper; Robert Lawrence; George Stavrides; Jilur Ghori; Pamela Whittaker; ANDREW COLLINS; Andrew P Morris; David Bentley; Lon R Cardon; Panos Deloukas
The impact of SNP density on fine-scale patterns of linkage disequilibrium.
Human molecular genetics 2004;13(6):577-88.
2004: Steven Wiltshire; Timothy M Frayling; Christopher J Groves; Jonathan C Levy; Graham A Hitman; Mike Sampson; Mark Walker; Stephan Menzel; Andrew T Hattersley; Lon R Cardon; Mark I McCarthy
Evidence from a large U.K. family collection that genes influencing age of onset of type 2 diabetes map to chromosome 12p and to the MODY3/NIDDM2 locus on 12q24.
Diabetes 2004;53(3):855-60.
2004: Krina T Zondervan; Daniel E Weeks; Ricki Colman; Lon R Cardon; Ruth Hadfield; Joan Schleffler; Amanda Goudy Trainor; Christopher L Coe; Joseph W Kemnitz; Stephen Kennedy
Familial aggregation of endometriosis in a large pedigree of rhesus macaques.
Human reproduction (Oxford, England) 2004;19(2):448-55.
2004: Krina T Zondervan; Lon R Cardon
The complex interplay among factors that influence allelic association.
Nature reviews. Genetics 2004;5(2):89-100.
2003: David A van Heel; Bryan M Dechairo; Gary Dawson; Dermot P B McGovern; Kenichi Negoro; Alisoun Carey; Lon R Cardon; Ian Mackay; Derek P Jewell; Nicholas J Lench
The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease-associated variants.
Human molecular genetics 2003;12(20):2569-75.
2003: Emma L Duncan; Lon R Cardon; Janet S Sinsheimer; J A H Wass; Matthew A Brown
Site and gender specificity of inheritance of bone mineral density.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(8):1531-8.
2003: Loukia-Maria Mitsos; Lon R Cardon; Lynn Ryan; Ronald LaCourse; Robert J North; Philippe Gros
Susceptibility to tuberculosis: a locus on mouse chromosome 19 (Trl-4) regulates Mycobacterium tuberculosis replication in the lungs.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(11):6610-5.
2003: Kenichi Negoro; Dermot P B McGovern; Y Kinouchi; S Takahashi; Nicholas J Lench; T Shimosegawa; Alisoun Carey; Lon R Cardon; Derek P Jewell; David A van Heel
Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease.
Gut 2003;52(4):541-6.
2003: Lon R Cardon; Goncalo Abecasis
Using haplotype blocks to map human complex trait loci.
Trends in genetics : TIG 2003;19(3):135-40.
2003: Angela J Marlow; Simon E Fisher; Clyde Francks; I Laurence MacPhie; Stacey Cherny; Alexandra Richardson; Joel B Talcott; John Stein; Anthony P Monaco; Lon R Cardon
Use of multivariate linkage analysis for dissection of a complex cognitive trait.
American journal of human genetics 2003;72(3):561-70.
2003: Lon R Cardon; Lyle Palmer
Population stratification and spurious allelic association.
Lancet 2003;361(9357):598-604.
2003: Xiayi Ke; Lon R Cardon
Efficient selective screening of haplotype tag SNPs.
Bioinformatics (Oxford, England) 2003;19(2):287-8.
2002: Steven Wiltshire; Lon R Cardon; Mark I McCarthy
Evaluating the results of genomewide linkage scans of complex traits by locus counting.
American journal of human genetics 2002;71(5):1175-82.
2002: Katherine M Kirk; Lon R Cardon
The impact of genotyping error on haplotype reconstruction and frequency estimation.
European journal of human genetics : EJHG 2002;10(10):616-22.
2002: David A van Heel; Dermot P B McGovern; Lon R Cardon; Bryan M Dechairo; Nicholas J Lench; Alisoun Carey; Derek P Jewell
Fine mapping of the IBD1 locus did not identify Crohn disease-associated NOD2 variants: implications for complex disease genetics.
American journal of medical genetics 2002;111(3):253-9.
2002: Elisabeth Dawson; Goncalo Abecasis; Suzannah Bumpstead; Yuan Chen; Sarah Hunt; David M Beare; Jagjit Pabial; Thomas Dibling; Emma Tinsley; Susan Kirby; David Carter; Marianna Papaspyridonos; Simon Livingstone; Rocky Ganske; Elin Lõhmussaar; Jana Zernant; Neeme Tõnisson; Maido Remm; Reedik Mägi; Tarmo Puurand; Jaak Vilo; Ants Kurg; Kate Rice; Panos Deloukas; Richard Mott; Andres Metspalu; David R Bentley; Lon R Cardon; Carl Bruder
A first-generation linkage disequilibrium map of human chromosome 22.
Nature 2002;418(6897):544-8.
2002: Krina T Zondervan; Lon R Cardon; Stephen Kennedy
What makes a good case-control study? Design issues for complex traits such as endometriosis.
Human reproduction (Oxford, England) 2002;17(6):1415-23.
2002: David A van Heel; Irina A Udalova; Arjuna P De Silva; Dermot P B McGovern; Yoshitaka Kinouchi; Jeremy Hull; Nicholas J Lench; Lon R Cardon; Alisoun Carey; Derek P Jewell; Dominic Kwiatkowski
Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors.
Human molecular genetics 2002;11(11):1281-9.
2002: Erik G Willcutt; Bruce F Pennington; Shelley D Smith; Lon R Cardon; Javier Gayán; Valerie S Knopik; Richard K Olson; John C DeFries
Quantitative trait locus for reading disability on chromosome 6p is pleiotropic for attention-deficit/hyperactivity disorder.
American journal of medical genetics 2002;114(3):260-8.
2002: Roy Pettipher; Lon R Cardon
The application of genetics to the discovery of better medicines.
Pharmacogenomics 2002;3(2):257-63.
2002: Steven Wiltshire; Timothy M Frayling; Andrew T Hattersley; Graham A Hitman; Mark Walker; Jonathan C Levy; Stephen O'Rahilly; Christopher J Groves; Stephan Menzel; Lon R Cardon; Mark I McCarthy
Evidence for linkage of stature to chromosome 3p26 in a large U.K. Family data set ascertained for type 2 diabetes.
American journal of human genetics 2002;70(2):543-6.
2002: Simon E Fisher; Clyde Francks; Angela J Marlow; I Laurence MacPhie; Dianne F Newbury; Lon R Cardon; Yumiko Ishikawa-Brush; Alexandra Richardson; Joel B Talcott; Javier Gayán; Richard K Olson; Bruce F Pennington; Shelley D Smith; John C DeFries; John Stein; Anthony P Monaco
Independent genome-wide scans identify a chromosome 18 quantitative-trait locus influencing dyslexia.
Nature genetics 2002;30(1):86-91.
2002: Goncalo Abecasis; Stacey Cherny; William O Cookson; Lon R Cardon
Merlin--rapid analysis of dense genetic maps using sparse gene flow trees.
Nature genetics 2002;30(1):97-101.
2001: C J Davis; Javier Gayán; Valerie S Knopik; Shelley D Smith; Lon R Cardon; Bruce F Pennington; Richard K Olson; John C DeFries
Etiology of reading difficulties and rapid naming: the Colorado Twin Study of Reading Disability.
Behavior genetics 2001;31(6):625-35.
2001: Anny Fortin; Lon R Cardon; Mifong Tam; Emil Skamene; Mary M Stevenson; Philippe Gros
Identification of a new malaria susceptibility locus (Char4) in recombinant congenic strains of mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10793-8.
2001: Steven Wiltshire; Andrew T Hattersley; Graham A Hitman; Mark Walker; Jonathan C Levy; M Sampson; Stephen O'Rahilly; Timothy M Frayling; J I Bell; G Mark Lathrop; Amanda Bennett; R Dhillon; C Fletcher; Christopher J Groves; E Jones; P Prestwich; N Simecek; PV Rao; Marie Wishart; Gian Franco Bottazzo; R Foxon; S Howell; Damian Smedley; Lon R Cardon; Stephan Menzel; Mark I McCarthy
A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q.
American journal of human genetics 2001;69(3):553-69.
2001: Goncalo Abecasis; Stacey Cherny; William O C M Cookson; Lon R Cardon
GRR: graphical representation of relationship errors.
Bioinformatics (Oxford, England) 2001;17(8):742-3.
2001: Jasmin Hamersma; Lon R Cardon; Linda Bradbury; Sinead Brophy; Irene E van der Horst-Bruinsma; Andrei Calin; Matthew A Brown
Is disease severity in ankylosing spondylitis genetically determined?
Arthritis and rheumatism 2001;44(6):1396-400.
2001: Goncalo Abecasis; W O Cookson; Lon R Cardon
The power to detect linkage disequilibrium with quantitative traits in selected samples.
American journal of human genetics 2001;68(6):1463-74.
2001: Angela J Marlow; Simon E Fisher; Alexandra Richardson; Clyde Francks; Joel B Talcott; Anthony P Monaco; John Stein; Lon R Cardon
Investigation of quantitative measures related to reading disability in a large sample of sib-pairs from the UK.
Behavior genetics 2001;31(2):219-30.
2001: Goncalo Abecasis; Stacey Cherny; Lon R Cardon
The impact of genotyping error on family-based analysis of quantitative traits.
European journal of human genetics : EJHG 2001;9(2):130-4.
2001: Lon R Cardon; J I Bell
Association study designs for complex diseases.
Nature reviews. Genetics 2001;2(2):91-9.
2001: Goncalo Abecasis; Lon R Cardon; William O C M Cookson; P C Sham; Stacey Cherny
Association analysis in a variance components framework.
Genetic epidemiology 2001;21 Suppl 1():S341-6.
2001: Stacey Cherny; Goncalo Abecasis; William O C M Cookson; P C Sham; Lon R Cardon
The effect of genotype and pedigree error on linkage analysis: analysis of three asthma genome scans.
Genetic epidemiology 2001;21 Suppl 1():S117-22.
2001: Goncalo Abecasis; E Noguchi; Andrea Heinzmann; James A Traherne; Sumit Bhattacharyya; Nicholas I Leaves; Gavin G Anderson; Youming Zhang; Nicholas J Lench; Alisoun Carey; Lon R Cardon; Miriam F Moffatt; William O C M Cookson
Extent and distribution of linkage disequilibrium in three genomic regions.
American journal of human genetics 2001;68(1):191-197.
2000: Loukia-Maria Mitsos; Lon R Cardon; Anny Fortin; Lynn Ryan; Ronald LaCourse; Robert J North; Philippe Gros
Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice.
Genes and immunity 2000;1(8):467-77.
2000: Lon R Cardon
A sib-pair regression model of linkage disequilibrium for quantitative traits.
Human heredity 2000;50(6):350-8.
2000: Goncalo Abecasis; W O Cookson; Lon R Cardon
Pedigree tests of transmission disequilibrium.
European journal of human genetics : EJHG 2000;8(7):545-51.
2000: Lon R Cardon; Chad Garner; Simon T Bennett; Ian J Mackay; R M Edwards; Jillian Cornish; Madhuri Hegde; MA Murray; Ian R Reid; Tim Cundy
Evidence for a major gene for bone mineral density in idiopathic osteoporotic families.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(6):1132-7.
2000: Lon R Cardon; Goncalo Abecasis
Some properties of a variance components model for fine-mapping quantitative trait loci.
Behavior genetics 2000;30(3):235-43.
2000: Stéphane Chavanas; Chad Garner; Christine Bodemer; M Ali; D H Teillac; J Wilkinson; Jean-Louis Bonafé; M Paradisi; D P Kelsell; Shin-ichi Ansai; Yoshihiko Mitsuhashi; M Larrègue; I M Leigh; John I Harper; Alain Taïeb; Y d Prost; Lon R Cardon; Alain Hovnanian
Localization of the Netherton syndrome gene to chromosome 5q32, by linkage analysis and homozygosity mapping.
American journal of human genetics 2000;66(3):914-21.
2000: Goncalo Abecasis; Lon R Cardon; William O C M Cookson
A general test of association for quantitative traits in nuclear families.
American journal of human genetics 2000;66(1):279-92.
1999: Javier Gayán; Shelley D Smith; Stacey Cherny; Lon R Cardon; DW Fulker; AM Brower; Richard K Olson; Bruce F Pennington; John C DeFries
Quantitative-trait locus for specific language and reading deficits on chromosome 6p.
American journal of human genetics 1999;64(1):157-64.