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Tino Krell

Research Profile

Chemicals & Drugs

Living Beings

Pseudomonas putida

Concepts & Ideas

Phenomena

Procedures

Calorimetry

Physiology

Gene Expression Regulation, Bacterial

Genes & Molecular Sequences

Occupations

Thermodynamics

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Publications

TOP 3
Emma Sevilla; Hortencia Silva-Jiménez; Estrella Duque; Tino Krell; Fernando Rojo
The Pseudomonas putida HskA hybrid sensor kinase controls the composition of the electron transport chain.
Estela Pineda-Molina; Juan L Ramos; José-Antonio Reyes-Darias; Juan Manuel García-Ruiz; Jose A. Gavira; Jesús Lacal; Tino Krell
Evidence for chemoreceptors with bimodular ligand-binding regions harboring two signal-binding sites.
Zulema Udaondo; Jesús de la Torre; M Antonia Molina-Henares; Amalia Roca; Ana Segura; Hortencia Silva-Jiménez; Patricia Bernal; Andreas Busch; Estrella Duque; Matilde Fernández; Tino Krell; Jesús Lacal; Miguel A Matilla; Lázaro Molina; Gloria Navarro-Avilés; José-Luis Niqui; Cecilia Pini; Juan-Luis Ramos
Analysis of solvent tolerance in Pseudomonas putida DOT-T1E based on its genome sequence and a collection of mutants.

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All Publications

2013: Emma Sevilla; Hortencia Silva-Jiménez; Estrella Duque; Tino Krell; Fernando Rojo
The Pseudomonas putida HskA hybrid sensor kinase controls the composition of the electron transport chain.
Environmental microbiology reports 2013;5(2):291-300.
2012: Estela Pineda-Molina; Juan L Ramos; José-Antonio Reyes-Darias; Juan Manuel García-Ruiz; Jose A. Gavira; Jesús Lacal; Tino Krell
Evidence for chemoreceptors with bimodular ligand-binding regions harboring two signal-binding sites.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(46):18926-31.
2012: Zulema Udaondo; Jesús de la Torre; M Antonia Molina-Henares; Amalia Roca; Ana Segura; Hortencia Silva-Jiménez; Patricia Bernal; Andreas Busch; Estrella Duque; Matilde Fernández; Tino Krell; Jesús Lacal; Miguel A Matilla; Lázaro Molina; Gloria Navarro-Avilés; José-Luis Niqui; Cecilia Pini; Juan-Luis Ramos
Analysis of solvent tolerance in Pseudomonas putida DOT-T1E based on its genome sequence and a collection of mutants.
FEBS letters 2012;586(18):2932-8.
2012: Tino Krell; Jesús Lacal; Francisco Muñoz-Martínez; Andreas Busch; Estrella Duque; Sandy Fillet; Cristina García-Fontana; Jesus Lacal; José A Reyes-Darías; Miriam Rico-Jiménez; Ana Segura; Hortencia Silva-Jiménez; Juan-Luis Ramos
Responses of Pseudomonas putida to toxic aromatic carbon sources.
Journal of biotechnology 2012;160(1-2):25-32.
2012: Hortencia Silva-Jiménez; Bilge Hilal Cadirci; Cristina García-Fontana; Juan Luis Ramos; María Isabel Ramos-González; Tino Krell
Study of the TmoS/TmoT two-component system: towards the functional characterization of the family of TodS/TodT like systems.
Microbial biotechnology 2012;5(4):489-500.
2012: Ana Segura; Patricia Bernal; Sandy Fillet; Tino Krell; Lázaro Molina; Jesús Muñoz-Rojas; Juan-Luis Ramos
Solvent tolerance in Gram-negative bacteria.
Current opinion in biotechnology 2012;23(3):415-21.
2012: Hortencia Silva-Jiménez; Juan Luis Ramos; Tino Krell
Construction of a prototype two-component system from the phosphorelay system TodS/TodT.
Protein engineering, design & selection : PEDS 2012;25(4):159-69.
2012: Francisco Muñoz-Martínez; Miriam Rico-Jiménez; Carlos Alfonso; Cristina García-Fontana; Tino Krell
Genes encoding Cher-TPR fusion proteins are predominantly found in gene clusters encoding chemosensory pathways with alternative cellular functions.
PloS one 2012;7(9):e45810.
2012: Abdelali Daddaoua; Matilde Fernández; Sandy Fillet; Tino Krell; Zulema Udaondo; Juan L Ramos
Genes for carbon metabolism and the ToxA virulence factor in Pseudomonas aeruginosa are regulated through molecular interactions of PtxR and PtxS.
PloS one 2012;7(7):e39390.
2012: Saray Santamaría-Hernando; Tino Krell; María Isabel Ramos-González
Identification of a novel calcium binding motif based on the detection of sequence insertions in the animal peroxidase domain of bacterial proteins.
PloS one 2012;7(7):e40698.
2011: Bernard Desbat; Tino Krell; Eloïse Lancelot; Marie-Claire Nicolaï; Michel Chevalier; Fred Vogel; Frédéric Ronzon
Effect of the β-propiolactone treatment on the adsorption and fusion of influenza A/Brisbane/59/2007 and A/New Caledonia/20/1999 virus H1N1 on a dimyristoylphosphatidylcholine/ganglioside GM3 mixed phospholipids monolayer at the air-water interface.
Langmuir : the ACS journal of surfaces and colloids 2011;27(22):13675-83.
2011: Nadège Moreno; Frédéric Ronzon; Michel Chevalier; Monique Dupuy; Tino Krell; Catherine Manin; Jean-Paul Rieu
Unbinding forces of single pertussis toxin-antibody complexes measured by atomic force spectroscopy correlate with their dissociation rates determined by surface plasmon resonance.
Journal of molecular recognition : JMR 2011;24(6):1105-14.
2011: Sandy Fillet; Tino Krell; Duo Lu; Bertrand Morel; Xiaodong Zhang; Juan L Ramos
Intramolecular signal transmission in a tetrameric repressor of the IclR family.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(37):15372-7.
2011: Jesús Lacal; Miguel Matilla; Francisco Muñoz-Martínez; José-J Ortega Calvo; Estrella Duque; Celía Jímenez-Sánchez; Tino Krell; José-Antonio Reyes-Darías; Ana Segura; Juan L Ramos
Bacterial chemotaxis towards aromatic hydrocarbons in Pseudomonas.
Environmental microbiology 2011;13(7):1733-44.
2011: Tino Krell; Jesus Lacal; Francisco Muñoz-Martínez; José Antonio Reyes-Darias; Bilge Hilal Cadirci; Cristina García-Fontana; Juan Luis Ramos
Diversity at its best: bacterial taxis.
Environmental microbiology 2011;13(5):1115-24.
2011: Jesus Lacal; Cristina García-Fontana; Carla Callejo-García; Juan-Luis Ramos; Tino Krell
Physiologically relevant divalent cations modulate citrate recognition by the McpS chemoreceptor.
Journal of molecular recognition : JMR 2011;24(2):378-85.
2010: Duo Lu; Sandy Fillet; Cuixiang Meng; Yilmaz Alguel; Patrik Kloppsteck; Julien Bergeron; Tino Krell; María-Trinidad Gallegos; Juan Ramos; Xiaodong Zhang
Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators.
Genes & development 2010;24(22):2556-65.
2010: Jesus Lacal; Cristina García-Fontana; Francisco Muñoz-Martínez; Juan-Luis Ramos; Tino Krell
Sensing of environmental signals: classification of chemoreceptors according to the size of their ligand binding regions.
Environmental microbiology 2010;12(11):2873-84.
2010: Andreas Busch; Jesus Lacal; Hortencia Silva-Jímenez; Tino Krell; Juan L Ramos
Catabolite repression of the TodS/TodT two-component system and effector-dependent transphosphorylation of TodT as the basis for toluene dioxygenase catabolic pathway control.
Journal of bacteriology 2010;192(16):4246-50.
2010: Tino Krell; Jesus Lacal; Andreas Busch; Hortencia Silva-Jiménez; María-Eugenia Guazzaroni; Juan Luis Ramos
Bacterial sensor kinases: diversity in the recognition of environmental signals.
Annual review of microbiology 2010;64():539-59.
2009: M Carmen HERRERA; Tino Krell; Xiaodong Zhang; Juan L Ramos
PhhR binds to target sequences at different distances with respect to RNA polymerase in order to activate transcription.
Journal of molecular biology 2009;394(3):576-86.
2009: Craig Daniels; Carmen Michán; Tino Krell; Amalia Roca; Juan L Ramos
The heat, drugs and knockout systems of microbial biotechnology.
Microbial biotechnology 2009;2(6):598-600.
2009: Abdelali Daddaoua; Tino Krell; Juan-Luis Ramos
Regulation of glucose metabolism in Pseudomonas: the phosphorylative branch and entner-doudoroff enzymes are regulated by a repressor containing a sugar isomerase domain.
The Journal of biological chemistry 2009;284(32):21360-8.
2009: Andreas Busch; Jesus Lacal; Jesús Lacal; Juan L Ramos; Tino Krell
The sensor kinase TodS operates by a multiple step phosphorelay mechanism involving two autokinase domains.
The Journal of biological chemistry 2009;284(16):10353-60.
2009: Juan L Ramos; Tino Krell; Craig Daniels; Ana Segura; Estrella Duque
Responses of Pseudomonas to small toxic molecules by a mosaic of domains.
Current opinion in microbiology 2009;12(2):215-20.
2008: Jesús Lacal; Jesus Lacal; Paloma Gutiérrez-del-Arroyo; Andreas Busch; Marisela Vélez; Tino Krell; Juan L Ramos
Two levels of cooperativeness in the binding of TodT to the tod operon promoter.
Journal of molecular biology 2008;384(5):1037-47.
2008: Tino Krell
Microcalorimetry: a response to challenges in modern biotechnology.
Microbial biotechnology 2008;1(2):126-36.
2008: Jesús Lacal; Jesus Lacal; Andreas Busch; Tino Krell; Juan L Ramos
Hierarchical binding of the TodT response regulator to its multiple recognition sites at the tod pathway operon promoter.
Journal of molecular biology 2008;376(2):325-37.
2008: Sergio Barranco-Medina; Tino Krell; Laura Bernier-Villamor; Francisca Sevilla; Juan-José Lázaro; Karl-Josef Dietz
Hexameric oligomerization of mitochondrial peroxiredoxin PrxIIF and formation of an ultrahigh affinity complex with its electron donor thioredoxin Trx-o.
Journal of experimental botany 2008;59(12):3259-69.
2007: Wilson Terán; Antonia Felipe; Sandy Fillet; María-Eugenia Guazzaroni; Tino Krell; Raquel Ruiz; Juan L Ramos; María-Trinidad Gallegos
Complexity in efflux pump control: cross-regulation by the paralogues TtgV and TtgT.
Molecular microbiology 2007;66(6):1416-28.
2007: Sergio Barranco-Medina; Tino Krell; Iris Finkemeier; Francisca Sevilla; Juan-José Lázaro; Karl-Josef Dietz
Biochemical and molecular characterization of the mitochondrial peroxiredoxin PsPrxII F from Pisum sativum.
Plant physiology and biochemistry : PPB / Société française de physiologie végétale 2007;45(10-11):729-39.
2007: Andreas Busch; Jesus Lacal; Ariadna Martos; Juan L Ramos; Tino Krell
Bacterial sensor kinase TodS interacts with agonistic and antagonistic signals.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(34):13774-9.
2007: Tino Krell; Wilson Terán; Obdulio López Mayorga; Germán Rivas; Mercedes Jiménez; Craig Daniels; Antonio J Molina-Henares; Manuel Martínez-Bueno; María-Trinidad Gallegos; Juan L Ramos
Optimization of the palindromic order of the TtgR operator enhances binding cooperativity.
Journal of molecular biology 2007;369(5):1188-99.
2007: María-Eugenia Guazzaroni; Tino Krell; Paloma Gutiérrez del Arroyo; Marisela Vélez; Mercedes Jiménez; Germán Rivas; Juan L Ramos
The transcriptional repressor TtgV recognizes a complex operator as a tetramer and induces convex DNA bending.
Journal of molecular biology 2007;369(4):927-39.
2007: Yilmaz Alguel; Cuixiang Meng; Wilson Terán; Tino Krell; Juan L Ramos; María-Trinidad Gallegos; Xiaodong Zhang
Crystal structures of multidrug binding protein TtgR in complex with antibiotics and plant antimicrobials.
Journal of molecular biology 2007;369(3):829-40.
2007: María-Eugenia Guazzaroni; María-Trinidad Gallegos; Juan L Ramos; Tino Krell
Different modes of binding of mono- and biaromatic effectors to the transcriptional regulator TTGV: role in differential derepression from its cognate operator.
The Journal of biological chemistry 2007;282(22):16308-16.
2006: Jesús Lacal; Andreas Busch; Jesus Lacal; Tino Krell; Juan L Ramos
The TodS-TodT two-component regulatory system recognizes a wide range of effectors and works with DNA-bending proteins.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8191-6.
2006: Tino Krell; Antonio J Molina-Henares; Juan L Ramos
The IclR family of transcriptional activators and repressors can be defined by a single profile.
Protein science : a publication of the Protein Society 2006;15(5):1207-13.
2006: Wilson Terán; Tino Krell; Juan L Ramos; María-Trinidad Gallegos
Effector-repressor interactions, binding of a single effector molecule to the operator-bound TtgR homodimer mediates derepression.
The Journal of biological chemistry 2006;281(11):7102-9.
2006: Antonio J Molina-Henares; Tino Krell; Maria Eugenia Guazzaroni; Ana Segura; Juan L Ramos
Members of the IclR family of bacterial transcriptional regulators function as activators and/or repressors.
FEMS microbiology reviews 2006;30(2):157-86.
2005: Tino Krell; Catherine Manin; Marie-Claire Nicolaï; Catherine Pierre-Justin; Yves Bérard; Olivier Brass; Lionel Gérentes; Patricia Leung-Tack; Michel Chevalier
Characterization of different strains of poliovirus and influenza virus by differential scanning calorimetry.
Biotechnology and applied biochemistry 2005;41(Pt 3):241-6.
2005: María-Eugenia Guazzaroni; Tino Krell; Antonia Felipe; Raquel Ruiz; Cuixiang Meng; Xiaodong Zhang; María-Trinidad Gallegos; Juan L Ramos
The multidrug efflux regulator TtgV recognizes a wide range of structurally different effectors in solution and complexed with target DNA: evidence from isothermal titration calorimetry.
The Journal of biological chemistry 2005;280(21):20887-93.
2005: Bruno Guy; Tino Krell; Violette Sanchez; Audrey Kennel; Catherine Manin; Régis Sodoyer
Do Th1 or Th2 sequence motifs exist in proteins? Identification of amphipatic immunomodulatory domains in Helicobacter pylori catalase.
Immunology letters 2005;96(2):261-75.
2004: Geneviève Renauld-Mongénie; David Poncet; Michèle Mignon; Sophie Fraysse; Christophe Chabanel; Bernard Danve; Tino Krell; Marie-José Quentin-Millet
Role of transferrin receptor from a Neisseria meningitidis tbpB isotype II strain in human transferrin binding and virulence.
Infection and immunity 2004;72(6):3461-70.
2004: Tino Krell; Frédéric Greco; Olivier Engel; Jean Dubayle; Joseline Dubayle; Audrey Kennel; Benoit Charloteaux; Robert Brasseur; Michel Chevalier; Régis Sodoyer; Raphaelle El Habib
HIV-1 gp41 and gp160 are hyperthermostable proteins in a mesophilic environment. Characterization of gp41 mutants.
European journal of biochemistry / FEBS 2004;271(8):1566-79.
2004: Geneviève Renauld-Mongénie; laurence lins; Tino Krell; Laure Laffly; Michèle Mignon; Monique Dupuy; Rose-May Delrue; Françoise Guinet-Morlot; Robert Brasseur; Ling Lissolo
Transferrin-binding protein B of Neisseria meningitidis: sequence-based identification of the transferrin-Binding site confirmed by site-directed mutagenesis.
Journal of bacteriology 2004;186(3):850-7.
2003: Tino Krell; Frédéric Greco; Marie-Claire Nicolaï; Jean Dubayle; Geneviève Renauld-Mongénie; Nadège Poisson; Isabelle Bernard
The use of microcalorimetry to characterize tetanus neurotoxin, pertussis toxin and filamentous haemagglutinin.
Biotechnology and applied biochemistry 2003;38(Pt 3):241-51.
2003: Tino Krell; Geneviève Renauld-Mongénie; Marie-Claire Nicolaï; Sophie Fraysse; Michel Chevalier; Yves Bérard; Jonathan Oakhill; Robert W Evans; Andrew R Gorringe; Ling Lissolo
Insight into the structure and function of the transferrin receptor from Neisseria meningitidis using microcalorimetric techniques.
The Journal of biological chemistry 2003;278(17):14712-22.
2002: Aleksander W Roszak; David A Robinson; Tino Krell; Iain S Hunter; Martyn Fredrickson; Chris Abell; John R Coggins; Adrian J Lapthorn
The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.
Structure (London, England : 1993) 2002;10(4):493-503.
2002: Tino Krell; Michel Chevalier; Ling Lissolo
Affinity-purification of Transferrin-binding protein B under nondenaturing conditions.
Protein expression and purification 2002;24(3):323-8.
2002: Craig William Roberts; Fiona Roberts; Russell E Lyons; Michael J Kirisits; Ernest J Mui; John Finnerty; Jennifer J Johnson; David J P Ferguson; John R Coggins; Tino Krell; Graham H Coombs; Wilbur K Milhous; Dennis E Kyle; Saul Tzipori; John W Barnwell; John B Dame; Jane Carlton; Rima McLeod
The shikimate pathway and its branches in apicomplexan parasites.
The Journal of infectious diseases 2002;185 Suppl 1():S25-36.
2002: P P Pastoret; R Sitrin; O W Merten; J C Vincent Falquet; M Schwanig; M Welin; I Hegger; R Neeleman; T van der Velden; A Urital; S Rene; Marie-Emmanuelle BEHR-GROSS; M Smith; J McArdle; S Prior; C Schmidt; Tino Krell; Michel Chevalier; H Klein; U Rosskopf-Streicher; C Jaekel
New vaccine production technologies and their impact on the use of animals.
Developments in biologicals 2002;111():219-20.
2001: H de Wet; D B McIntosh; Gwenaëlle Conseil; Hélène Baubichon-Cortay; Tino Krell; Jean-Michel Jault; Jean-Baptiste Daskiewicz; Denis Barron; Attilio Di Pietro
Sequence requirements of the ATP-binding site within the C-terminal nucleotide-binding domain of mouse P-glycoprotein: structure-activity relationships for flavonoid binding.
Biochemistry 2001;40(34):10382-91.
2001: Tino Krell; John Maclean; Deborah J Boam; Alan Cooper; Marina Resmini; Keith Brocklehurst; Sharon M Kelly; Nicholas C Price; Adrian J Lapthorn; John R Coggins
Biochemical and X-ray crystallographic studies on shikimate kinase: the important structural role of the P-loop lysine.
Protein science : a publication of the Protein Society 2001;10(6):1137-49.
1999: Attilio Di Pietro; Guila Dayan; Gwenaëlle Conseil; Emmanuelle Steinfels; Tino Krell; Doriane Trompier; Hélène Baubichon-Cortay; Jean-Michel Jault
P-glycoprotein-mediated resistance to chemotherapy in cancer cells: using recombinant cytosolic domains to establish structure-function relationships.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1999;32(8):925-39.
1999: David G Gourley; Annette K Shrive; Igor Polikarpov; Tino Krell; John R Coggins; Alastair R Hawkins; N W Isaacs; Lindsay Sawyer
The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction.
Nature structural biology 1999;6(6):521-5.
1999: Nicholas C Price; Deborah J Boam; Sharon M Kelly; D Duncan; Tino Krell; David G Gourley; John R Coggins; R Virden; Alastair R Hawkins
The folding and assembly of the dodecameric type II dehydroquinases.
The Biochemical journal 1999;338 ( Pt 1)():195-202.
1998: Fiona Roberts; Craig William Roberts; Jennifer J Johnson; Dennis E Kyle; Tino Krell; John R Coggins; Graham H Coombs; Wilbur K Milhous; Saul Tzipori; David J P Ferguson; Debopam Chakrabarti; Rima McLeod
Evidence for the shikimate pathway in apicomplexan parasites.
Nature 1998;393(6687):801-5.
1998: Tino Krell; John R Coggins; Adrian J Lapthorn
The three-dimensional structure of shikimate kinase.
Journal of molecular biology 1998;278(5):983-97.
1998: Tino Krell; S Chackrewarthy; Andrew Pitt; A Elwell; John R Coggins
Chemical modification monitored by electrospray mass spectrometry: a rapid and simple method for identifying and studying functional residues in enzymes.
The journal of peptide research : official journal of the American Peptide Society 1998;51(3):201-9.
1997: C Idziak; Nicholas C Price; Sharon M Kelly; Tino Krell; Deborah J Boam; Adrian J Lapthorn; John R Coggins
The interaction of shikimate kinase from Erwinia chrystanthemi with substrates.
Biochemical Society transactions 1997;25(4):S627.
1997: Tino Krell; J E Coyle; M J Horsburgh; John R Coggins; Adrian J Lapthorn
Crystallization and preliminary X-ray crystallographic analysis of shikimate kinase from Erwinia chrysanthemi.
Acta crystallographica. Section D, Biological crystallography 1997;53(Pt 5):612-4.
1997: Deborah J Boam; Nicholas C Price; Sharon M Kelly; Tino Krell; John R Coggins
Evidence that the active site in type II dehydroquinase from Streptomyces coelicolor is near the single tryptophan.
Biochemical Society transactions 1997;25(1):348; replaces 93S.
1996: Tino Krell; M J Horsburgh; Alan Cooper; Sharon M Kelly; John R Coggins
Localization of the active site of type II dehydroquinases. Identification of a common arginine-containing motif in the two classes of dehydroquinases.
The Journal of biological chemistry 1996;271(40):24492-7.
1996: Jacqueline Nairn; Nicholas C Price; Sharon M Kelly; Daniel J Rigden; Linda A Fothergill-Gilmore; Tino Krell
Phosphoglycerate mutase from Schizosaccharomyces pombe: development of an expression system and characterisation of three histidine mutants of the enzyme.
Biochimica et biophysica acta 1996;1296(1):69-75.
1996: M Conner; Tino Krell; J Gordon Lindsay
Identification and purification of a distinct dihydrolipoamide dehydrogenase from pea chloroplasts.
Planta 1996;200(2):195-202.
1995: Thomas Arendt; Martina K Brückner; Tino Krell; sonia pagliusi; L Kruska; R Heumann
Degeneration of rat cholinergic basal forebrain neurons and reactive changes in nerve growth factor expression after chronic neurotoxic injury--II. Reactive expression of the nerve growth factor gene in astrocytes.
Neuroscience 1995;65(3):647-59.
1995: Thomas Arendt; Martina K Brückner; sonia pagliusi; Tino Krell
Degeneration of rat cholinergic basal forebrain neurons and reactive changes in nerve growth factor expression after chronic neurotoxic injury--I. Degeneration and plastic response of basal forebrain neurons.
Neuroscience 1995;65(3):633-45.
1995: Tino Krell; Andrew Pitt; John R Coggins
The use of electrospray mass spectrometry to identify an essential arginine residue in type II dehydroquinases.
FEBS letters 1995;360(1):93-6.
1995: Jacqueline Nairn; Tino Krell; John R Coggins; Andrew Pitt; Linda A Fothergill-Gilmore; R Walter; Nicholas C Price
The use of mass spectrometry to examine the formation and hydrolysis of the phosphorylated form of phosphoglycerate mutase.
FEBS letters 1995;359(2-3):192-4.