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Andreas Till

Research Profile

Chemicals & Drugs

Disorders

Crohn's Disease

Physiology

Anatomy

Co-author Network

Publications

TOP 3
Christian Sina; Andreas Till; Paul Saftig; Stefan Schreiber; Konrad Aden; Olga Gavrilova; Robert Haesler; Simone Lipinski; Michael A McGuckin; Ulf Meyer-Hoffert; Emilie Midtling; Rainer Podschun; Katrin Pütsep; Ateequr Rehman; Andrea Rittger; Philip Rosenstiel
Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice.
Stefanie Derer; Nils Grabe; Joachim Groetzinger; Robert Haesler; Sascha Jung; Tanja Kuehbacher; Susanna Nikolaus; Stefan Rose-John; Philip Rosenstiel; Christian Sina; Andreas Till; Stefan Schreiber
mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease.
Simone Lipinski; Maren Paulsen; Stefan Schreiber; Andreas Till; Konrad Aden; Alexander Arlt; Susanne Billmann-Born; Kai Sven Erdmann; Nils Grabe; Nina Hagemann; Robert Häsler; Gunnar Jacobs; Lars Kraemer; Philip Rosenstiel
RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition.

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All Publications

2013: Christian Sina; Andreas Till; Paul Saftig; Stefan Schreiber; Konrad Aden; Olga Gavrilova; Robert Haesler; Simone Lipinski; Michael A McGuckin; Ulf Meyer-Hoffert; Emilie Midtling; Rainer Podschun; Katrin Pütsep; Ateequr Rehman; Andrea Rittger; Philip Rosenstiel
Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice.
Gut 2013;62(4):520-30.
2013: Stefanie Derer; Nils Grabe; Joachim Groetzinger; Robert Haesler; Sascha Jung; Tanja Kuehbacher; Susanna Nikolaus; Stefan Rose-John; Philip Rosenstiel; Christian Sina; Andreas Till; Stefan Schreiber
mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease.
Gut 2013;62(3):376-86.
2012: Simone Lipinski; Maren Paulsen; Stefan Schreiber; Andreas Till; Konrad Aden; Alexander Arlt; Susanne Billmann-Born; Kai Sven Erdmann; Nils Grabe; Nina Hagemann; Robert Häsler; Gunnar Jacobs; Lars Kraemer; Philip Rosenstiel
RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(52):21426-31.
2012: Robert Häsler; Gunnar Jacobs; kaiqin lao; Susanna Nikolaus; Christian Cordes; Nils Grabe; Stefan Schreiber; Andreas Till; Philip Rosenstiel
Microbial pattern recognition causes distinct functional micro-RNA signatures in primary human monocytes.
PloS one 2012;7(2):e31151.
2011: M Laudien; S Lipinski; Rainer Podschun; Philip Rosenstiel; Petra Ambrosch; J Böck; L Bremer; Robert Häsler; P Lamprecht; J Wohlers; Andreas Till
Molecular signatures of a disturbed nasal barrier function in the primary tissue of Wegener's granulomatosis.
Mucosal immunology 2011;4(5):564-73.
2011: Susanne Billmann-Born; Simone Lipinski; Janne Böck; Andreas Till; Philip Rosenstiel; Stefan Schreiber
The complex interplay of NOD-like receptors and the autophagy machinery in the pathophysiology of Crohn disease.
European journal of cell biology 2011;90(6-7):593-602.
2011: Susanne Billmann-Born; Andreas Till; Alexander Arlt; Simone Lipinski; Christian Sina; Anna Latiano; Vito Annese; Robert Häsler; Martin Kerick; Thomas Manke; Dirk Seegert; Adedayo Hanidu; Heiner Schäfer; David van Heel; Jun Li; Stefan Schreiber; Philip Rosenstiel
Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(7):4027-38.
2010: Oliver von Kampen; Simone Lipinski; Andreas Till; Seamus J Martin; Wilfried Nietfeld; Hans Lehrach; Stefan Schreiber; Philip Rosenstiel
Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling.
The Journal of biological chemistry 2010;285(26):19921-6.
2010: Sven Kuenzel; Andreas Till; Michael Winkler; Robert Häsler; Simone Lipinski; Sascha Jung; Joachim Grötzinger; Helmut Fickenscher; Stefan Schreiber; Philip Rosenstiel
The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(4):1990-2000.
2010: Marlo Möller; Friederike Flachsbart; Andreas Till; Thorsten Thye; Rolf D Horstmann; Christian G Meyer; Ivy Osei; Paul D van Helden; Eileen G Hoal; Stefan Schreiber; Almut Nebel; Andre Franke
A functional haplotype in the 3'untranslated region of TNFRSF1B is associated with tuberculosis in two African populations.
American journal of respiratory and critical care medicine 2010;181(4):388-93.
2009: Christian Sina; Olga Gavrilova; Matti Förster; Andreas Till; Stefanie Derer; Friederike Hildebrand; Björn Raabe; Athena Chalaris; Jürgen Scheller; Ateequr Rehmann; Andre Franke; Stephan Ott; Robert Häsler; Susanna Nikolaus; Ulrich R Fölsch; Stefan Rose-John; Hui-Ping Jiang; Jun Li; Stefan Schreiber; Philip Rosenstiel
G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(11):7514-22.
2009: Simone Lipinski; Andreas Till; Christian Sina; Alexander Arlt; Helmut Grasberger; Stefan Schreiber; Philip Rosenstiel
DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses.
Journal of cell science 2009;122(Pt 19):3522-30.
2009: Almut Nebel; Friederike Flachsbart; Andreas Till; Amke Caliebe; Hélène Blanché; Alexander Arlt; Robert Häsler; Gunnar Jacobs; Rabea Kleindorp; Andre Franke; Binghui Shen; Susanna Nikolaus; Michael Krawczak; Philip Rosenstiel; Stefan Schreiber
A functional EXO1 promoter variant is associated with prolonged life expectancy in centenarians.
Mechanisms of ageing and development 2009;130(10):691-9.
2009: A Brosbøl-Ravnborg; C L Hvas; Jørgen Agnholt; Jens F Dahlerup; I Vind; Andreas Till; Philip Rosenstiel; Per Höllsberg
Toll-like receptor-induced granulocyte-macrophage colony-stimulating factor secretion is impaired in Crohn's disease by nucleotide oligomerization domain 2-dependent and -independent pathways.
Clinical and experimental immunology 2009;155(3):487-95.
2008: Andre Franke; Annegret Fischer; Michael Nothnagel; Christian Becker; Nils Grabe; Andreas Till; Tim Lu; Joachim Müller-Quernheim; Michael Wittig; Alexander Hermann; Tobias Balschun; Sylvia Hofmann; Regina Niemiec; Sabrina Schulz; Jochen Hampe; Susanna Nikolaus; Peter Nürnberg; Michael Krawczak; Manfred Schürmann; Philip Rosenstiel; Almut Nebel; Stefan Schreiber
Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2.
Gastroenterology 2008;135(4):1207-15.
2008: M Laudien; Petra Ambrosch; Andreas Till; Rainer Podschun; P Lamprecht
[Diagnosis, therapy and current research aspects of selected chronic inflammatory diseases with head and neck involvement].
Zeitschrift für Rheumatologie 2008;67(5):397-406.
2008: Philip Rosenstiel; G Jacobs; Andreas Till; S Schreiber
NOD-like receptors: ancient sentinels of the innate immune system.
Cellular and molecular life sciences : CMLS 2008;65(9):1361-77.
2008: P Lamprecht; Andreas Till; D Kabelitz
[New aspects of the pathogenesis of gout. Danger signals, autoinflammation and beyond].
Zeitschrift für Rheumatologie 2008;67(2):151-6.
2008: Philip Rosenstiel; Stefanie Derer; Andreas Till; Robert Häsler; H Eberstein; Burkhard Bewig; S Nikolaus; Almut Nebel; Stefan Schreiber
Systematic expression profiling of innate immune genes defines a complex pattern of immunosenescence in peripheral and intestinal leukocytes.
Genes and immunity 2008;9(2):103-14.
2008: Andreas Till; Philip Rosenstiel; Karen Bräutigam; Christian Sina; Gunnar Jacobs; Hans-Heinrich Oberg; Dirk Seegert; Trinad Chakraborty; Stefan Schreiber
A role for membrane-bound CD147 in NOD2-mediated recognition of bacterial cytoinvasion.
Journal of cell science 2008;121(Pt 4):487-95.
2007: Peter Lamprecht; Andreas Till; Jörg Steinmann; Peer M Aries; Wolfgang L Gross
Current state of biologicals in the management of systemic vasculitis.
Annals of the New York Academy of Sciences 2007;1110():261-70.
2007: Philip Rosenstiel; Christian Sina; Caroline End; Marcus Renner; Stefan Lyer; Andreas Till; Stephan Hellmig; Susanna Nikolaus; Ulrich R Fölsch; Burkhard Helmke; Frank Autschbach; Peter Schirmacher; Petra Kioschis; Mathias Hafner; Annemarie Poustka; Jan Mollenhauer; Stefan Schreiber
Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):8203-11.
2007: Philip Rosenstiel; Andreas Till; Stefan Schreiber
NOD-like receptors and human diseases.
Microbes and infection / Institut Pasteur 2007;9(5):648-57.
2007: Jochen Hampe; Andre Franke; Philip Rosenstiel; Andreas Till; Markus Teuber; Klaus Huse; Mario Albrecht; Gabriele Mayr; Francisco M De La Vega; Jason Briggs; Simone Günther; Natalie Prescott; Clive M Onnie; Robert Häsler; Bence Sipos; Ulrich R Fölsch; Thomas Lengauer; Matthias Platzer; Christopher G Mathew; Michael Krawczak; Stefan Schreiber
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1.
Nature genetics 2007;39(2):207-11.
2006: Philip Rosenstiel; Stephan Hellmig; Jochen Hampe; Stephan Ott; Andreas Till; Wolfgang Fischbach; Hany Sahly; Ralph Lucius; Ulrich R Fölsch; Dana Philpott; Stefan Schreiber
Influence of polymorphisms in the NOD1/CARD4 and NOD2/CARD15 genes on the clinical outcome of Helicobacter pylori infection.
Cellular microbiology 2006;8(7):1188-98.
2006: Philip Rosenstiel; Klaus Huse; Andreas Till; Jochen Hampe; Stephan Hellmig; Christian Sina; Susanne Billmann; Oliver von Kampen; Georg H Waetzig; Matthias Platzer; Dirk Seegert; Stefan Schreiber
A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3280-5.
2005: Andreas Till; Philip Rosenstiel; Anja Krippner-Heidenreich; Silvia Mascheretti-Croucher; Peter J P Croucher; Heiner Schäfer; Peter Scheurich; Dirk Seegert; Stefan Schreiber
The Met-196 -> Arg variation of human tumor necrosis factor receptor 2 (TNFR2) affects TNF-alpha-induced apoptosis by impaired NF-kappaB signaling and target gene expression.
The Journal of biological chemistry 2005;280(7):5994-6004.
2005: Georg H Waetzig; Philip Rosenstiel; Alexander Arlt; Andreas Till; Karen Bräutigam; Heiner Schäfer; Stefan Rose-John; Dirk Seegert; Stefan Schreiber
Soluble tumor necrosis factor (TNF) receptor-1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor-beta1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(1):91-3.
2004: Stefan Thomsen; Andreas Till; Jörg Wittlieb; christian beetz; Konstantin Khalturin; Thomas C G Bosch
Control of foot differentiation in Hydra: in vitro evidence that the NK-2 homeobox factor CnNK-2 autoregulates its own expression and uses pedibin as target gene.
Mechanisms of development 2004;121(2):195-204.