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Holm Schneider

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Aisa Khodzhigorova; Veronika Lang; Georg Schett; Holm Schneider; Christian Beyer; Clara Dees; Alfiya Distler; Oliver Distler; Kolja Gelse; Jörg H W Distler
Inhibition of sumoylation prevents experimental fibrosis.
Fabian B Fahlbusch; Andrea Hartner; Carlos Menendez-Castro; Stephanie C Nögel; Wolfgang Rascher; Matthias Rübner; Ralf L Schild; Ekkehard Schleussner; Holm Schneider; Pamela L Strissel; Anja Tzschoppe; Matthias W Beckmann; Yousif Dawood; Helmuth G Dörr; Jörg Dötsch
Cullin 7 and Fbxw 8 expression in trophoblastic cells is regulated via oxygen tension: implications for intrauterine growth restriction?
Alfiya Akhmetshina; Christina Bergmann; Christian Beyer; Clara Dees; Oliver Distler; Angelika Horn; Trayana Kireva; Ormond A MacDougald; Katrin Palumbo; Marc-Oliver Riener; Anika Sadowski; Georg Schett; Holm Schneider; Paulius Venalis; Pawel Zerr; Jochen Zwerina; Jörg H W Distler
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis.

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All Publications

2012: Aisa Khodzhigorova; Veronika Lang; Georg Schett; Holm Schneider; Christian Beyer; Clara Dees; Alfiya Distler; Oliver Distler; Kolja Gelse; Jörg H W Distler
Inhibition of sumoylation prevents experimental fibrosis.
Annals of the rheumatic diseases 2012;71(11):1904-8.
2012: Fabian B Fahlbusch; Andrea Hartner; Carlos Menendez-Castro; Stephanie C Nögel; Wolfgang Rascher; Matthias Rübner; Ralf L Schild; Ekkehard Schleussner; Holm Schneider; Pamela L Strissel; Anja Tzschoppe; Matthias W Beckmann; Yousif Dawood; Helmuth G Dörr; Jörg Dötsch
Cullin 7 and Fbxw 8 expression in trophoblastic cells is regulated via oxygen tension: implications for intrauterine growth restriction?
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2012;25(11):2209-15.
2012: Alfiya Akhmetshina; Christina Bergmann; Christian Beyer; Clara Dees; Oliver Distler; Angelika Horn; Trayana Kireva; Ormond A MacDougald; Katrin Palumbo; Marc-Oliver Riener; Anika Sadowski; Georg Schett; Holm Schneider; Paulius Venalis; Pawel Zerr; Jochen Zwerina; Jörg H W Distler
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis.
Nature communications 2012;3():735.
2011: Frederic Pacho; Valentina Calabresi; Dimitra Kiritsi; Giovanna Zambruno; Holm Schneider
Efficiency of translation termination in humans is highly dependent upon nucleotides in the neighbourhood of a (premature) termination codon.
Journal of medical genetics 2011;48(9):640-4.
2011: Johanna E Hammersen; Valentin Neukam; Kai-Dietrich Nüsken; Holm Schneider
Systematic evaluation of exertional hyperthermia in children and adolescents with hypohidrotic ectodermal dysplasia: an observational study.
Pediatric research 2011;70(3):297-301.
2011: Holm Schneider; Johanna Hammersen; Sabine Preisler-Adams; Kenneth Huttner; Wolfgang Rascher; Axel Bohring
Sweating ability and genotype in individuals with X-linked hypohidrotic ectodermal dysplasia.
Journal of medical genetics 2011;48(6):426-32.
2011: Kai-Dietrich Nüsken; Holm Schneider; Christian Plank; Regina Trollmann; Eva Nüsken; Wolfgang Rascher; Jörg Dötsch
Fetal programming of gene expression in growth-restricted rats depends on the cause of low birth weight.
Endocrinology 2011;152(4):1327-35.
2011: Miguel Angel Alejandre Alcázar; Lisa Lendzian; Rory E Morty; Iris Oestreicher; Christian Plank; Holm Schneider; Christina Vohlen; Jörg Dötsch
Inhibition of TGF-β signaling and decreased apoptosis in IUGR-associated lung disease in rats.
PloS one 2011;6(10):e26371.
2011: Kolja Gelse; Holm Schneider
In vivo evaluation of gene transfer into mesenchymal cells (in view of cartilage repair).
Methods in molecular biology (Clifton, N.J.) 2011;737():391-405.
2010: Anja Mühle; Christiane Mühle; Kerstin Amann; Jörg Dötsch; Kai-Dietrich Nüsken; Johannes Boltze; Holm Schneider
No juvenile arterial hypertension in sheep multiples despite reduced nephron numbers.
Pediatric nephrology (Berlin, Germany) 2010;25(9):1653-61.
2010: Gert Blüschke; Kai-Dietrich Nüsken; Holm Schneider
Prevalence and prevention of severe complications of hypohidrotic ectodermal dysplasia in infancy.
Early human development 2010;86(7):397-9.
2009: Stephanie C Nögel; Martin Chada; Ana-Marija Schmidt; Stephan Bosselmann; Michael Kandler; Horst Schweer; Bernhard Watzer; Holm Schneider; Andre Gessner; Wolfgang Rascher
Parecoxib does not suppress thromboxane synthesis in newborn piglets with group B streptococcal sepsis.
Prostaglandins & other lipid mediators 2009;90(1-2):7-12.
2009: Kai-Dietrich Nüsken; Maurice Petrasch; Manfred Rauh; Wolfgang Stöhr; Eva Nüsken; Holm Schneider; Jörg Dötsch
Active visfatin is elevated in serum of maintenance haemodialysis patients and correlates inversely with circulating HDL cholesterol.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(9):2832-8.
2009: Benjamin Frey; Luis E Munoz; Friederike Pausch; Renate Sieber; Sandra Franz; Bent Brachvogel; Ernst Poschl; Holm Schneider; Franz Rödel; Rolf Sauer; Rainer Fietkau; Martin Herrmann; Udo S Gaipl
The immune reaction against allogeneic necrotic cells is reduced in Annexin A5 knock out mice whose macrophages display an anti-inflammatory phenotype.
Journal of cellular and molecular medicine 2009;13(7):1391-9.
2009: Holm Schneider; Christiane Mühle
X-chromosomal insertions at a recurrent site causing ectodermal dysplasia.
European journal of dermatology : EJD 2009;19(2):178-9.
2009: Jung Park; Viviane Setter; Viktor Wixler; Holm Schneider
Umbilical cord blood stem cells: induction of differentiation into mesenchymal lineages by cell-cell contacts with various mesenchymal cells.
Tissue engineering. Part A 2009;15(2):397-406.
2008: Kolja Gelse; Christiane Mühle; K Knaup; Bernd Swoboda; Michael S Wiesener; Friedrich F Hennig; Alexander Olk; Holm Schneider
Chondrogenic differentiation of growth factor-stimulated precursor cells in cartilage repair tissue is associated with increased HIF-1alpha activity.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2008;16(12):1457-65.
2008: Jung Park; Carola Will; Bernd Martin; Lucia Gullotti; Nicolaus Friedrichs; Reinhard Buettner; Holm Schneider; Stephan Ludwig; Viktor Wixler
Deficiency in the LIM-only protein FHL2 impairs assembly of extracellular matrix proteins.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(7):2508-20.
2008: Holm Schneider; Christiane Muehle
Gene symbol: LAMC2. Disease: Epidermolysis Bullosa, Herlitz.
Human genetics 2008;123(5):544.
2008: Kai-Dietrich Nüsken; Jörg Dötsch; Manfred Rauh; Wolfgang Rascher; Holm Schneider
Uteroplacental insufficiency after bilateral uterine artery ligation in the rat: impact on postnatal glucose and lipid metabolism and evidence for metabolic programming of the offspring by sham operation.
Endocrinology 2008;149(3):1056-63.
2008: Kolja Gelse; Christiane Mühle; Oliver Franke; Jung Park; Marc Jehle; Karsten Durst; Mathias Göken; Friedrich F Hennig; Klaus von der Mark; Holm Schneider
Cell-based resurfacing of large cartilage defects: long-term evaluation of grafts from autologous transgene-activated periosteal cells in a porcine model of osteoarthritis.
Arthritis and rheumatism 2008;58(2):475-88.
2007: Christiane Mühle; Holm Schneider
Novel human pathological mutations. Gene symbol: LAMA3. Disease: junctional epidermolysis bullosa.
Human genetics 2007;122(5):549.
2007: Holm Schneider; Christiane Mühle; Frederic Pacho
Biological function of laminin-5 and pathogenic impact of its deficiency.
European journal of cell biology 2007;86(11-12):701-17.
2007: O Franke; K Durst; V Maier; M Göken; Torsten Birkholz; Holm Schneider; Friedrich F Hennig; Kolja Gelse
Mechanical properties of hyaline and repair cartilage studied by nanoindentation.
Acta biomaterialia 2007;3(6):873-81.
2007: Christiane Mühle; Martin Zenker; Nadia Chuzhanova; Holm Schneider
Recurrent inversion with concomitant deletion and insertion events in the coagulation factor VIII gene suggests a new mechanism for X-chromosomal rearrangements causing hemophilia A.
Human mutation 2007;28(10):1045.
2007: Benedikt Hartwig; Bodo Borm; Holm Schneider; Meral J Arin; Gregor Kirfel; Volker Herzog
Laminin-5-deficient human keratinocytes: defective adhesion results in a saltatory and inefficient mode of migration.
Experimental cell research 2007;313(8):1575-87.
2007: Viktor Wixler; Stephanie Hirner; Judith M Müller; Lucia Gullotti; Carola Will; Jutta Kirfel; Thomas Günther; Holm Schneider; Anja Bosserhoff; Hubert Schorle; Jung Park; Roland Schüle; Reinhard Buettner
Deficiency in the LIM-only protein Fhl2 impairs skin wound healing.
The Journal of cell biology 2007;177(1):163-72.
2007: Kai-Dietrich Nüsken; Christina Warnecke; Karl F Hilgers; Holm Schneider
Intrauterine growth after uterine artery ligation in rats: dependence on the fetal position in the uterine horn and need for prenatal marking of the animals.
Journal of hypertension 2007;25(1):247-8.
2006: Christiane Mühle; A Neuner; Jung Park; Frederic Pacho; Q Jiang; Simon Waddington; Holm Schneider
Evaluation of prenatal intra-amniotic LAMB3 gene delivery in a mouse model of Herlitz disease.
Gene therapy 2006;13(23):1665-76.
2006: K Gelse; Holm Schneider
Ex vivo gene therapy approaches to cartilage repair.
Advanced drug delivery reviews 2006;58(2):259-84.
2006: Jung Park; Kolja Gelse; Susi Frank; Klaus von der Mark; Thomas Aigner; Holm Schneider
Transgene-activated mesenchymal cells for articular cartilage repair: a comparison of primary bone marrow-, perichondrium/periosteum- and fat-derived cells.
The journal of gene medicine 2006;8(1):112-25.
2005: Holm Schneider; C Muehle
Gene symbol: LAMB3. Disease: junctional epidermolysis bullosa, Herlitz variant.
Human genetics 2005;118(3-4):545.
2005: Suzanne Buckley; Simon Waddington; Sarah Jezzard; Lorraine Lawrence; Holm Schneider; Maxine V Holder; Michael Themis; Charles Coutelle
Factors influencing adenovirus-mediated airway transduction in fetal mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(3):484-92.
2005: Holm Schneider; C Muehle
Gene symbol: KRT14. Disease: Epidermolysis bullosa simplex.
Human genetics 2005;117(2-3):298.
2005: Marcus Jakob; Christiane Mühle; Jung Park; Susi Weiss; Simon Waddington; Holm Schneider
No evidence for germ-line transmission following prenatal and early postnatal AAV-mediated gene delivery.
The journal of gene medicine 2005;7(5):630-7.
2005: Jürgen Kopp; Raimund E Horch; Klaus-Daniel Stachel; Wolfgang Holter; Michael A Kandler; Holger Hertzberg; Wolfgang Rascher; Valentina Campean; Roman Carbon; Holm Schneider
Hematopoietic stem cell transplantation and subsequent 80% skin exchange by grafts from the same donor in a patient with Herlitz disease.
Transplantation 2005;79(2):255-6.
2005: Christiane Mühle; Qiu-Jie Jiang; Alexandra Charlesworth; Leena Bruckner-Tuderman; Guerrino Meneguzzi; Holm Schneider
Novel and recurrent mutations in the laminin-5 genes causing lethal junctional epidermolysis bullosa: molecular basis and clinical course of Herlitz disease.
Human genetics 2005;116(1-2):33-42.
2004: Christiane Mühle; Stefan Schulz-Drost; Alexey V Khrenov; Evgueni L Saenko; Jens Klinge; Holm Schneider
Epitope mapping of polyclonal clotting factor VIII-inhibitory antibodies using phage display.
Thrombosis and haemostasis 2004;91(3):619-25.
2003: Kolja Gelse; Klaus von der Mark; Holm Schneider
Cartilage regeneration by gene therapy.
Current gene therapy 2003;3(4):305-17.
2003: Jung Park; J Ries; Kolja Gelse; Frank Rudolf Kloss; Klaus von der Mark; Jörg Wiltfang; Friedrich Wilhelm Neukam; Holm Schneider
Bone regeneration in critical size defects by cell-mediated BMP-2 gene transfer: a comparison of adenoviral vectors and liposomes.
Gene therapy 2003;10(13):1089-98.
2003: Anna David; Terry Cook; Simon Waddington; Donald M Peebles; Megha Nivsarkar; Holly J Knapton; Maznu Miah; Thomas Dahse; David Noakes; Holm Schneider; Charles Rodeck; Charles Coutelle; Michael Themis
Ultrasound-guided percutaneous delivery of adenoviral vectors encoding the beta-galactosidase and human factor IX genes to early gestation fetal sheep in utero.
Human gene therapy 2003;14(4):353-64.
2003: Simon Waddington; Suzanne Buckley; Megha Nivsarkar; Sarah Jezzard; Holm Schneider; Thomas Dahse; Geoffrey Kemball-Cook; Maznu Miah; Nicholas P Tucker; Margaret J Dallman; Michael Themis; Charles Coutelle
In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor.
Blood 2003;101(4):1359-66.
2003: Kolja Gelse; Klaus von der Mark; Thomas Aigner; Jung Park; Holm Schneider
Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells.
Arthritis and rheumatism 2003;48(2):430-41.
2002: Qiu-Jie Jiang; Jan Izakovic; Martin Zenker; Manige Fartasch; Guerrino Meneguzzi; Wolfgang Rascher; Holm Schneider
Treatment of two patients with Herlitz junctional epidermolysis bullosa with artificial skin bioequivalents.
The Journal of pediatrics 2002;141(4):553-9.
2002: Holm Schneider; Christiane Mühle; Anne-Marie Douar; Simon Waddington; Qiu-Jie Jiang; Klaus von der Mark; Charles Coutelle; Wolfgang Rascher
Sustained delivery of therapeutic concentrations of human clotting factor IX--a comparison of adenoviral and AAV vectors administered in utero.
The journal of gene medicine 2002;4(1):46-53.
2001: Kolja Gelse; Qiu-Jie Jiang; Thomas Aigner; T Ritter; K Wagner; Ernst Pöschl; Klaus von der Mark; Holm Schneider
Fibroblast-mediated delivery of growth factor complementary DNA into mouse joints induces chondrogenesis but avoids the disadvantages of direct viral gene transfer.
Arthritis and rheumatism 2001;44(8):1943-53.
2001: P J Jost; Richard P Harbottle; A Knight; Andrew D Miller; Charles Coutelle; Holm Schneider
A novel peptide, THALWHT, for the targeting of human airway epithelia.
FEBS letters 2001;489(2-3):263-9.
2001: Charles Coutelle; Michael Themis; Holm Schneider; T Kiserud; Terry Cook; Anne-Marie Douar; M Hanson; A Pavirani; Charles Rodeck
Fetal somatic gene therapy--a preventive approach to the treatment of genetic disease: the case for.
Ernst Schering Research Foundation workshop 2001;(33):99-114.
2000: Antje Böttner; A Haidan; Graeme Eisenhofer; K Kristensen; A L Castle; Werner A Scherbaum; Holm Schneider; George Chrousos; Stefan R Bornstein
Increased body fat mass and suppression of circulating leptin levels in response to hypersecretion of epinephrine in phenylethanolamine-N-methyltransferase (PNMT)-overexpressing mice.
Endocrinology 2000;141(11):4239-46.
2000: Holm Schneider; M Groves; Christiane Mühle; P N Reynolds; Andrew Knight; Michael Themis; Jaime Carvajal; F Scaravilli; D T Curiel; Neil Fairweather; Charles Coutelle
Retargeting of adenoviral vectors to neurons using the Hc fragment of tetanus toxin.
Gene therapy 2000;7(18):1584-92.
2000: K Sinha; Michael Box; Giovanna Lalli; Giampietro Schiavo; Holm Schneider; M Groves; G Siligardi; Neil Fairweather
Analysis of mutants of tetanus toxin Hc fragment: ganglioside binding, cell binding and retrograde axonal transport properties.
Molecular microbiology 2000;37(5):1041-51.
2000: Morvane Colin; Sylviane Moritz; Holm Schneider; Jacqueline Capeau; Charles Coutelle; Marie Christiane Brahimi-Horn
Haemoglobin interferes with the ex vivo luciferase luminescence assay: consequence for detection of luciferase reporter gene expression in vivo.
Gene therapy 2000;7(15):1333-6.
1999: Yasuyuki Yokosaki; N Matsuura; T Sasaki; Isao Murakami; Holm Schneider; S Higashiyama; Y Saitoh; M Yamakido; Y Taooka; Dean Sheppard
The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin.
The Journal of biological chemistry 1999;274(51):36328-34.
1999: Holm Schneider; S Adebakin; Michael Themis; Terry Cook; Anne-Marie Douar; A Pavirani; Charles Coutelle
Therapeutic plasma concentrations of human factor IX in mice after gene delivery into the amniotic cavity: a model for the prenatal treatment of haemophilia B.
The journal of gene medicine 1999;1(6):424-32.
1999: Holm Schneider; Richard P Harbottle; Yasuyuki Yokosaki; P Jost; Charles Coutelle
Targeted gene delivery into alpha9beta1-integrin-displaying cells by a synthetic peptide.
FEBS letters 1999;458(3):329-32.
1999: Michael Themis; Holm Schneider; T Kiserud; Terry Cook; S Adebakin; Sarah Jezzard; Stuart Forbes; M Hanson; A Pavirani; Charles Rodeck; Charles Coutelle
Successful expression of beta-galactosidase and factor IX transgenes in fetal and neonatal sheep after ultrasound-guided percutaneous adenovirus vector administration into the umbilical vein.
Gene therapy 1999;6(7):1239-48.
1999: Holm Schneider; Charles Coutelle
In utero gene therapy: the case for.
Nature medicine 1999;5(3):256-7.
1999: Andrew Knight; Jaime Carvajal; Holm Schneider; Charles Coutelle; Susan Chamberlain; Neil Fairweather
Non-viral neuronal gene delivery mediated by the HC fragment of tetanus toxin.
European journal of biochemistry / FEBS 1999;259(3):762-9.
1998: Holm Schneider; Richard P Harbottle; Yasuyuki Yokosaki; J Kunde; D Sheppard; Charles Coutelle
A novel peptide, PLAEIDGIELTY, for the targeting of alpha9beta1-integrins.
FEBS letters 1998;429(3):269-73.
1996: Holm Schneider; K Huse
Arterial gene therapy.
Lancet 1996;348(9038):1380-1; author reply 1381-2.
1996: Holm Schneider; Klaus Huse; Gerd Birkenmeier; Andreas Otto; Gerhard Scholz
Gene transfer mediated by alpha2-macroglobulin.
Nucleic acids research 1996;24(19):3873-4.
1996: Holm Schneider; W Barth; H J Böhme
Cloning and characterization of another lignin peroxidase gene from the white-rot fungus Phanerochaete chrysosporium.
Biological chemistry Hoppe-Seyler 1996;377(6):399-402.