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Guenter Auerbach

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Iris M Fritze; Lars Linden; Jörg Freigang; Guenter Auerbach; Robert Huber; Stefan Steinbacher
The crystal structures of Zea mays and Arabidopsis 4-hydroxyphenylpyruvate dioxygenase.
Stefan Gerhardt; Stefanie Echt; Marco Busch; Jörg Freigang; Guenter Auerbach; Gerd Bader; William F Martin; Adelbert Bacher; Robert Huber; Markus Fischer
Structure and properties of an engineered transketolase from maize.
Jorge Rebelo; Guenter Auerbach; Gerd Bader; Andreas Bracher; Herbert Nar; Cornelia Hösl; Nicholas Schramek; Johannes Kaiser; Adelbert Bacher; Robert Huber; Markus Fischer
Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I.

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All Publications

2004: Iris M Fritze; Lars Linden; Jörg Freigang; Guenter Auerbach; Robert Huber; Stefan Steinbacher
The crystal structures of Zea mays and Arabidopsis 4-hydroxyphenylpyruvate dioxygenase.
Plant physiology 2004;134(4):1388-400.
2003: Stefan Gerhardt; Stefanie Echt; Marco Busch; Jörg Freigang; Guenter Auerbach; Gerd Bader; William F Martin; Adelbert Bacher; Robert Huber; Markus Fischer
Structure and properties of an engineered transketolase from maize.
Plant physiology 2003;132(4):1941-9.
2003: Jorge Rebelo; Guenter Auerbach; Gerd Bader; Andreas Bracher; Herbert Nar; Cornelia Hösl; Nicholas Schramek; Johannes Kaiser; Adelbert Bacher; Robert Huber; Markus Fischer
Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I.
Journal of molecular biology 2003;326(2):503-16.
2002: Nicholas Schramek; Andreas Bracher; Markus Fischer; Guenter Auerbach; Herbert Nar; Robert Huber; Adelbert Bacher
Reaction mechanism of GTP cyclohydrolase I: single turnover experiments using a kinetically competent reaction intermediate.
Journal of molecular biology 2002;316(3):829-37.
2001: Gerd Bader; S Schiffmann; A Herrmann; Markus Fischer; M Gütlich; Guenter Auerbach; Ploom Tarmo; Adelbert Bacher; Robert Huber; T Lemm
Crystal structure of rat GTP cyclohydrolase I feedback regulatory protein, GFRP.
Journal of molecular biology 2001;312(5):1051-7.
2000: Guenter Auerbach; A Herrmann; Andreas Bracher; Gerd Bader; M Gutlich; Markus Fischer; M Neukamm; Marta Garrido-Franco; J Richardson; Herbert Nar; Robert Huber; Adelbert Bacher
Zinc plays a key role in human and bacterial GTP cyclohydrolase I.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(25):13567-72.
2000: Beat Thöny; Guenter Auerbach; N Blau
Tetrahydrobiopterin biosynthesis, regeneration and functions.
The Biochemical journal 2000;347 Pt 1():1-16.
2000: T Dams; Guenter Auerbach; Gerd Bader; Uwe Jacob; Ploom Tarmo; Robert Huber; Rainer Jaenicke
The crystal structure of dihydrofolate reductase from Thermotoga maritima: molecular features of thermostability.
Journal of molecular biology 2000;297(3):659-72.
1999: Andreas Bracher; Markus Fischer; Wolfgang Eisenreich; H Ritz; Nicholas Schramek; P Boyle; P Gentili; Robert Huber; Herbert Nar; Guenter Auerbach; Adelbert Bacher
Histidine 179 mutants of GTP cyclohydrolase I catalyze the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone triphosphate.
The Journal of biological chemistry 1999;274(24):16727-35.
1999: Ploom Tarmo; Beat Thöny; J Yim; S Lee; Herbert Nar; Walter Leimbacher; J Richardson; Robert Huber; Guenter Auerbach
Crystallographic and kinetic investigations on the mechanism of 6-pyruvoyl tetrahydropterin synthase.
Journal of molecular biology 1999;286(3):851-60.
1998: Guenter Auerbach; R Ostendorp; L Prade; I Korndörfer; T Dams; Robert Huber; Rainer Jaenicke
Lactate dehydrogenase from the hyperthermophilic bacterium thermotoga maritima: the crystal structure at 2.1 A resolution reveals strategies for intrinsic protein stabilization.
Structure (London, England : 1993) 1998;6(6):769-81.
1998: T Dams; G Böhm; Guenter Auerbach; Gerd Bader; H Schurig; Rainer Jaenicke
Homo-dimeric recombinant dihydrofolate reductase from Thermotoga maritima shows extreme intrinsic stability.
Biological chemistry 1998;379(3):367-71.
1997: Guenter Auerbach; A Herrmann; M Gütlich; Markus Fischer; Uwe Jacob; Adelbert Bacher; Robert Huber
The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters.
The EMBO journal 1997;16(24):7219-30.
1997: Guenter Auerbach; Robert Huber; M Grättinger; K Zaiss; H Schurig; Rainer Jaenicke; Uwe Jacob
Closed structure of phosphoglycerate kinase from Thermotoga maritima reveals the catalytic mechanism and determinants of thermal stability.
Structure (London, England : 1993) 1997;5(11):1475-83.
1997: Guenter Auerbach; Uwe Jacob; M Grättinger; H Schurig; Rainer Jaenicke
Crystallographic analysis of phosphoglycerate kinase from the hyperthermophilic bacterium Thermotoga maritima.
Biological chemistry 1997;378(3-4):327-9.
1997: Guenter Auerbach; Herbert Nar
The pathway from GTP to tetrahydrobiopterin: three-dimensional structures of GTP cyclohydrolase I and 6-pyruvoyl tetrahydropterin synthase.
Biological chemistry 1997;378(3-4):185-92.
1996: R Ostendorp; Guenter Auerbach; Rainer Jaenicke
Extremely thermostable L(+)-lactate dehydrogenase from Thermotoga maritima: cloning, characterization, and crystallization of the recombinant enzyme in its tetrameric and octameric state.
Protein science : a publication of the Protein Society 1996;5(5):862-73.
1995: Herbert Nar; Robert Huber; Guenter Auerbach; Markus Fischer; C Hösl; H Ritz; Andreas Bracher; Winfried Meining; Sabine Eberhardt; Adelbert Bacher
Active site topology and reaction mechanism of GTP cyclohydrolase I.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12120-5.
1995: Guenter Auerbach; F Gaill; Rainer Jaenicke; T Schulthess; Rupert Timpl; J Engel
Pressure dependence of collagen melting.
Matrix biology : journal of the International Society for Matrix Biology 1995;14(7):589-92.
1993: M Gross; Guenter Auerbach; Rainer Jaenicke
The catalytic activities of monomeric enzymes show complex pressure dependence.
FEBS letters 1993;321(2-3):256-60.