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Erhe Gao

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Wenjun Yan; Lu Yang; Haifeng Zhang; Lijian Zhang; Haichang Wang; Han Wang; Lize Xiong; Ling Dong; Chao Gao; Erhe Gao; Feng Gao; Yunping Guo; Wayne Bond Lau; Kun Lian; Jingyi Liu; Peilin Liu; Yi Liu; Yan Qu; Lu Sun; Ling Tao
Impaired mitochondrial biogenesis due to dysfunctional adiponectin-AMPK-PGC-1α signaling contributing to increased vulnerability in diabetic heart.
Mai Chen; J Kurt Chuprun; Erhe Gao; Jessica Ibetti; Nicholas J Otis; Shi Pan; Raymond J Peroutka; Priscila Y Sato; Shey-Shing Sheu; Walter J Koch
Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting.
Jibin Zhou; Firdos Ahmad; John Farber; Theresa A Freeman; Erhe Gao; Hind Lal; Xin-Liang Ma; Emily Mangano; Xiying Shang; Ronald J Vagnozzi; Yajing Wang; James Woodgett; Thomas Force
GSK-3α is a central regulator of age-related pathologies in mice.

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2013: Wenjun Yan; Lu Yang; Haifeng Zhang; Lijian Zhang; Haichang Wang; Han Wang; Lize Xiong; Ling Dong; Chao Gao; Erhe Gao; Feng Gao; Yunping Guo; Wayne Bond Lau; Kun Lian; Jingyi Liu; Peilin Liu; Yi Liu; Yan Qu; Lu Sun; Ling Tao
Impaired mitochondrial biogenesis due to dysfunctional adiponectin-AMPK-PGC-1α signaling contributing to increased vulnerability in diabetic heart.
Basic research in cardiology 2013;108(3):329.
2013: Mai Chen; J Kurt Chuprun; Erhe Gao; Jessica Ibetti; Nicholas J Otis; Shi Pan; Raymond J Peroutka; Priscila Y Sato; Shey-Shing Sheu; Walter J Koch
Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting.
Circulation research 2013;112(8):1121-34.
2013: Jibin Zhou; Firdos Ahmad; John Farber; Theresa A Freeman; Erhe Gao; Hind Lal; Xin-Liang Ma; Emily Mangano; Xiying Shang; Ronald J Vagnozzi; Yajing Wang; James Woodgett; Thomas Force
GSK-3α is a central regulator of age-related pathologies in mice.
The Journal of clinical investigation 2013;123(4):1821-32.
2013: Barbara A Miller; Jianliang Song; JuFang Wang; Xue-Qian Zhang; Shu-jen Chen; Kathleen Conrad; Arthur M Feldman; Erhe Gao; Tongda Gu; Iwona Hirschler-Laszkiewicz; Kerry Keefer; Walter J Koch; Muniswamy Madesh; Karthik Mallilankaraman; Joseph Y Cheung
The second member of transient receptor potential-melastatin channel family protects hearts from ischemia-reperfusion injury.
American journal of physiology. Heart and circulatory physiology 2013;304(7):H1010-22.
2013: Wayne Bond Lau; Baojiang Liu; Bernard Lopez; Xin L Ma; Xiaoliang Wang; Theodore A Christopher; Erhe Gao; Walter J Koch; Yuexing Yuan; Yanqing Zhang; Jianli Zhao; Yajing Wang
Lymphotoxin-α is a novel adiponectin expression suppressor following myocardial ischemia/reperfusion.
American journal of physiology. Endocrinology and metabolism 2013;304(6):E661-7.
2013: Xiaoying Zhang; Lin Zhou; Xiaojie Ai; Qin Fu; Erhe Gao; Hui Gao; Xinyi Joy Ge; Jianguo Jin; Satya P Kunapuli; Ying Li; Catherine Makarewich; Christopher Szeto; Allen Tang; Mingxin Tang; Fang Wang; Jenny Wang; Kevin Yang Xiang; Chunyu Zeng; Xiongwen Chen
Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling.
Circulation research 2013;112(3):498-509.
2013: Yanqing Zhang; Jianli Zhao; Yuexing Yuan; Erhe Gao; Li-Yuan Jiao; Walter J Koch; Wayne Bond Lau; Baojiang Liu; Xin-Liang Ma; Xiaoliang Wang; Yajing Wang
Tumor Necrosis Factor-α and Lymphotoxin-α Mediate Myocardial Ischemic Injury via TNF Receptor 1, but Are Cardioprotective When Activating TNF Receptor 2.
PloS one 2013;8(5):e60227.
2013: Jessica I Gold; Jonathan Hullmann; Donald M Bers; Julie Bossuyt; J Kurt Chuprun; Erhe Gao; Linda Lee; Jeffrey S Martini; Joseph E Rabinowitz; Douglas G Tilley; Walter J Koch
Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process.
PloS one 2013;8(3):e57324.
2013: Jufang Wang; Xue-Qian Zhang; Tung O Chan; Arthur M Feldman; Erhe Gao; Walter J Koch; Xiying Shang; Jianliang Song; Joseph Y Cheung
Induced overexpression of Na(+)/Ca(2+) exchanger does not aggravate myocardial dysfunction induced by transverse aortic constriction.
Journal of cardiac failure 2013;19(1):60-70.
2013: Joseph Y Cheung; Arthur M Feldman; Erhe Gao; Walter J Koch; Joseph E Rabinowitz; Jianliang Song; Tung O Chan; Xue-Qian Zhang; JuFang Wang
Coordinated regulation of cardiac Na(+)/Ca (2+) exchanger and Na (+)-K (+)-ATPase by phospholemman (FXYD1).
Advances in experimental medicine and biology 2013;961():175-90.
2013: Hui Su; Xiaoliang Wang; Xiao-Ming Wang; Yajing Wang; Yuexing Yuan; Erhe Gao; Walter J Koch; Wayne Bond Lau; Xin-Liang Ma
Inhibition of CTRP9, a novel and cardiac-abundantly expressed cell survival molecule, by TNFα-initiated oxidative signaling contributes to exacerbated cardiac injury in diabetic mice.
Basic research in cardiology 2013;108(1):315.
2012: David M Thal; Emily K Wu; Jun Chen; Joseph Y Cheung; J Kurt Chuprun; Erhe Gao; Patricia M Hinkle; Kristoff T Homan; Z Maggie Huang; Walter J Koch; Larry A Sklar; Jianliang Song; John J G Tesmer
Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility.
ACS chemical biology 2012;7(11):1830-9.
2012: Yi Liu; Xiaoyan Lu; Yanzhuo Ma; Yan Qu; Lu Sun; Chao Gao; Erhe Gao; Walter J Koch; Wayne B Lau; Kun Lian; Jingyi Liu; Haichang Wang; Rutao Wang; Chenhai Xia; Aibing Xu; Lu Yang; Ling Tao
The alternative crosstalk between RAGE and nitrative thioredoxin inactivation during diabetic myocardial ischemia-reperfusion injury.
American journal of physiology. Endocrinology and metabolism 2012;303(7):E841-52.
2012: Jessica I Gold; Richard T Premont; Xiying Shang; Erhe Gao; Walter J Koch
Determining the absolute requirement of G protein-coupled receptor kinase 5 for pathological cardiac hypertrophy: short communication.
Circulation research 2012;111(8):1048-53.
2012: A Kathleen McClendon; Christopher A Reed; Dayana B Rivadeneira; Justine E Yu; Jeffry L Dean; John L Farber; Thomas Force; Erhe Gao; Walter J Koch; Erik S Knudsen
CDK4/6 inhibition antagonizes the cytotoxic response to anthracycline therapy.
Cell cycle (Georgetown, Tex.) 2012;11(14):2747-55.
2012: Wei Yi; Yuexing Yuan; Qijun Zheng; Erhe Gao; Walter J Koch; Wayne Bond Lau; Xiying Shang; Yang Sun; Xiaoliang Wang; Yajing Wang; Xin-Liang Ma
C1q/tumor necrosis factor-related protein-3, a newly identified adipokine, is a novel antiapoptotic, proangiogenic, and cardioprotective molecule in the ischemic mouse heart.
Circulation 2012;125(25):3159-69.
2012: Philip Raake; Mingxin Tang; Leif Erik Vinge; Xiaoying Zhang; Yingxin Li; Patrick Most; Henriette Brinks; Xiongwen Chen; Gerald W Dorn; Erhe Gao; Steven R Houser; Naser Jaleel; Hugo A Katus; Walter J Koch
Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction.
Circulation 2012;125(17):2108-18.
2012: Yajing Wang; Wei Yi; Yuexin Yuan; Xiaoliang Wang; Kurt Chuprun; Erhe Gao; Jean-François Jasmin; Walter J Koch; Wayne Bond Lau; Rong Li; Michael P Lisanti; Xin-Liang Ma
Essential role of caveolin-3 in adiponectin signalsome formation and adiponectin cardioprotection.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(4):934-42.
2012: Hongyu Zhang; Remus M Berretta; Xiongwen Chen; Jason M Duran; Erhe Gao; Walter J Koch; Hajime Kubo; Ying Li; Catherine A Makarewich; Héctor H Valdivia; Wei Wang; Steven R Houser
Hyperphosphorylation of the cardiac ryanodine receptor at serine 2808 is not involved in cardiac dysfunction after myocardial infarction.
Circulation research 2012;110(6):831-40.
2012: David Swope; Lan Cheng; Erhe Gao; Jifen Li; Glenn L Radice
Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis.
Molecular and cellular biology 2012;32(6):1056-67.
2012: Jifen Li; Lan Cheng; Riet De Rycke; Erhe Gao; Steven Goossens; Xiying Shang; Koen Tyberghein; Jolanda van Hengel; Frans van Roy; Glenn L Radice
Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia.
Journal of cell science 2012;125(Pt 4):1058-67.
2012: Jianliang Song; Jufang Wang; Xue-Qian Zhang; Tung O Chan; Arthur M Feldman; Erhe Gao; Jeffrey I Joseph; Walter J Koch; Blaise Z Peterson; Xiying Shang; Joseph Y Cheung
Constitutive overexpression of phosphomimetic phospholemman S68E mutant results in arrhythmias, early mortality, and heart failure: potential involvement of Na+/Ca2+ exchanger.
American journal of physiology. Heart and circulatory physiology 2012;302(3):H770-81.
2012: Weizhong Zhu; Aizhi Zhao; Khalid Chakir; J Kurt Chuprun; Gerald W Dorn; Arthur M Feldman; Erhe Gao; Walter J Koch; Edward G Lakatta; Natalia Petrashevskaya; Shuxun Ren; Mark Talan; Yibin Wang; Rui-Ping Xiao
Gi-biased β2AR signaling links GRK2 upregulation to heart failure.
Circulation research 2012;110(2):265-74.
2012: Eman A Hamad; Walter J Koch; Xue Li; Valerie Myers; Jianliang Song; Jin Zhang; Xue-Qian Zhang; Weizhong Zhu; Tung O Chan; Joseph Y Cheung; Erhe Gao; Arthur M Feldman
Cardioprotection of controlled and cardiac-specific over-expression of A(2A)-adenosine receptor in the pressure overload.
PloS one 2012;7(7):e39919.
2011: Xue Li; Deana Mikhalkova; Valerie Myers; Karsten Peppel; Jianliang Song; Jin Zhang; Carmen Zincarelli; Joseph Y Cheung; Arthur M Feldman; Erhe Gao; Walter J Koch; Yonghong Lei; Tung O Chan
Myocardial injury after ischemia-reperfusion in mice deficient in Akt2 is associated with increased cardiac macrophage density.
American journal of physiology. Heart and circulatory physiology 2011;301(5):H1932-40.
2011: Wei Yi; Yuexing Yuan; Qijun Zheng; Erhe Gao; Walter J Koch; Wayne Bond Lau; Rong Li; Yang Sun; Ling Tao; Xiaoliang Wang; Yajing Wang; Xufeng Wei; Xin-Liang Ma
Reduced cardioprotective action of adiponectin in high-fat diet-induced type II diabetic mice and its underlying mechanisms.
Antioxidants & redox signaling 2011;15(7):1779-88.
2011: Yanzhuo Ma; Haifeng Pei; Yan Qu; Lu Sun; Yanjie Cao; Erhe Gao; Wayne Bond Lau; Kun Lian; Shaowei Liu; Yi Liu; Xiaoyan Lu; Haichang Wang; Rutao Wang; Chenhai Xia; Lu Yang; Tao Yin; Ling Tao
Dynamic alteration of adiponectin/adiponectin receptor expression and its impact on myocardial ischemia/reperfusion in type 1 diabetic mice.
American journal of physiology. Endocrinology and metabolism 2011;301(3):E447-55.
2011: Risto Kerkelä; Eileen O'Leary; Jarkko Piuhola; Raisa Serpi; Jianliang Song; Kathleen C Woulfe; Raihana Zaka; Joseph V Bonventre; Matthieu Boucher; Joseph Y Cheung; Erhe Gao; David Harris; Thomas Force
Cytosolic phospholipase A(2)α protects against ischemia/reperfusion injury in the heart.
Clinical and translational science 2011;4(4):236-42.
2011: Shaowei Liu; Yi Liu; Yanzhuo Ma; Haifeng Pei; Yan Qu; Lu Sun; Erhe Gao; Walter J Koch; Wayne Bond Lau; Kun Lian; Haichang Wang; Rutao Wang; Xufeng Wei; Chenhai Xia; Wei Yi; Tao Yin; Ling Tao
Downregulation of adiponectin induced by tumor necrosis factor α is involved in the aggravation of posttraumatic myocardial ischemia/reperfusion injury.
Critical care medicine 2011;39(8):1935-43.
2011: Michele Ciccarelli; J Kurt Chuprun; Giuseppe Rengo; Erhe Gao; Zhengyu Wei; Raymond J Peroutka; Jessica I Gold; Anna Gumpert; Mai Chen; Nicholas J Otis; Gerald W Dorn; Bruno Trimarco; guido iaccarino; Walter J Koch
G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia.
Circulation 2011;123(18):1953-62.
2011: Jufang Wang; Erhe Gao; Joseph Rabinowitz; Jianliang Song; Xue-Qian Zhang; Walter J Koch; Amy L Tucker; Tung O Chan; Arthur M Feldman; Joseph Y Cheung
Regulation of in vivo cardiac contractility by phospholemman: role of Na+/Ca2+ exchange.
American journal of physiology. Heart and circulatory physiology 2011;300(3):H859-68.
2010: Erhe Gao; Yong Hong Lei; Xiying Shang; Z Maggie Huang; Lin Zuo; Matthieu Boucher; Qian Fan; J Kurt Chuprun; Xin L Ma; Walter J Koch
A novel and efficient model of coronary artery ligation and myocardial infarction in the mouse.
Circulation research 2010;107(12):1445-53.
2010: Henriette Brinks; Matthieu Boucher; Erhe Gao; J Kurt Chuprun; Stéphanie Pesant; Philip W Raake; Z Maggie Huang; Xiaoliang Wang; Gang Qiu; Anna Gumpert; David M Harris; Andrea D Eckhart; Patrick Most; Walter J Koch
Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms.
Circulation research 2010;107(9):1140-9.
2010: Hongyu Zhang; Xiongwen Chen; Erhe Gao; Scott M MacDonnell; Wei Wang; Mikhail Kolpakov; Hiroyuki Nakayama; Xiaoying Zhang; Naser Jaleel; David M Harris; Yingxin Li; Mingxin Tang; Remus M Berretta; Annarosa Leri; Jan Kajstura; Abdelkarim Sabri; Walter J Koch; Jeffery D Molkentin; Steven R Houser
Increasing cardiac contractility after myocardial infarction exacerbates cardiac injury and pump dysfunction.
Circulation research 2010;107(6):800-9.
2010: Joseph Y Cheung; Xue-Qian Zhang; Jianliang Song; Erhe Gao; Joseph E Rabinowitz; Tung O Chan; Jufang Wang
Phospholemman: a novel cardiac stress protein.
Clinical and translational science 2010;3(4):189-96.
2010: Jibin Zhou; Hind Lal; Xiongwen Chen; Xiying Shang; Jianliang Song; Yingxin Li; Risto Kerkela; Bradley Doble; Katrina MacAulay; Morgan DeCaul; Walter J Koch; John Farber; James R Woodgett; Erhe Gao; Thomas Force
GSK-3alpha directly regulates beta-adrenergic signaling and the response of the heart to hemodynamic stress in mice.
The Journal of clinical investigation 2010;120(7):2280-91.
2010: Kathleen C Woulfe; Erhe Gao; Hind Lal; David Harris; Qian Fan; Ronald Vagnozzi; Morgan DeCaul; Xiying Shang; Satish Patel; James R Woodgett; Thomas Force; Jibin Zhou
Glycogen synthase kinase-3beta regulates post-myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivo.
Circulation research 2010;106(10):1635-45.
2010: Anastasios Lymperopoulos; Giuseppe Rengo; Erhe Gao; Steven N Ebert; Gerald W Dorn; Walter J Koch
Reduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarction.
The Journal of biological chemistry 2010;285(21):16378-86.
2010: Yajing Wang; Wayne Bond Lau; Erhe Gao; Ling Tao; Yuexing Yuan; Rong Li; Xiaoliang Wang; Walter J Koch; Xin-Liang Ma
Cardiomyocyte-derived adiponectin is biologically active in protecting against myocardial ischemia-reperfusion injury.
American journal of physiology. Endocrinology and metabolism 2010;298(3):E663-70.
2010: JuFang Wang; Erhe Gao; Jianliang Song; Xue-Qian Zhang; Jifen Li; Walter J Koch; Amy L Tucker; Kenneth D Philipson; Tung O Chan; Arthur M Feldman; Joseph Y Cheung
Phospholemman and beta-adrenergic stimulation in the heart.
American journal of physiology. Heart and circulatory physiology 2010;298(3):H807-15.
2010: Ling Tao; Yajing Wang; Erhe Gao; Hangxiang Zhang; Yuexing Yuan; Wayne B Lau; Lawrence Chan; Walter J Koch; Xin L Ma
Adiponectin: an indispensable molecule in rosiglitazone cardioprotection following myocardial infarction.
Circulation research 2010;106(2):409-17.
2009: JuFang Wang; Tung O Chan; Xue-Qian Zhang; Erhe Gao; Jianliang Song; Walter J Koch; Arthur M Feldman; Joseph Y Cheung
Induced overexpression of Na+/Ca2+ exchanger transgene: altered myocyte contractility, [Ca2+]i transients, SR Ca2+ contents, and action potential duration.
American journal of physiology. Heart and circulatory physiology 2009;297(2):H590-601.
2009: Erhe Gao; Walter J Koch
Is erythropoietin behind maladaptive anemic heart failure?
American journal of physiology. Heart and circulatory physiology 2009;296(3):H559-60.
2009: Xiang-Ying Jiao; Erhe Gao; Yuexin Yuan; Yajing Wang; Wayne Bond Lau; Walter J Koch; Xin-Liang Ma; Ling Tao
INO-4885 [5,10,15,20-tetra[N-(benzyl-4'-carboxylate)-2-pyridinium]-21H,23H-porphine iron(III) chloride], a peroxynitrite decomposition catalyst, protects the heart against reperfusion injury in mice.
The Journal of pharmacology and experimental therapeutics 2009;328(3):777-84.
2009: Yajing Wang; Erhe Gao; Ling Tao; Wayne Bond Lau; Yuexin Yuan; Barry J Goldstein; Bernard L Lopez; Theodore A Christopher; Rong Tian; Walter J Koch; Xin-Liang Ma
AMP-activated protein kinase deficiency enhances myocardial ischemia/reperfusion injury but has minimal effect on the antioxidant/antinitrative protection of adiponectin.
Circulation 2009;119(6):835-44.
2009: Hui-Rong Liu; Ling Tao; Erhe Gao; Yan Qu; Wayne Bond Lau; Bernard L Lopez; Theodore A Christopher; Walter J Koch; Tian-Li Yue; Xin-Liang Ma
Rosiglitazone inhibits hypercholesterolaemia-induced myeloperoxidase upregulation--a novel mechanism for the cardioprotective effects of PPAR agonists.
Cardiovascular research 2009;81(2):344-52.
2008: Brent R DeGeorge; Marc Rosenberg; Volker Eckstein; Erhe Gao; Nicole Herzog; Hugo A Katus; Walter J Koch; Norbert Frey; Patrick Most
BMP-2 and FGF-2 synergistically facilitate adoption of a cardiac phenotype in somatic bone marrow c-kit+/Sca-1+ stem cells.
Clinical and translational science 2008;1(2):116-25.
2008: Jeffrey S Martini; Philip Raake; Leif Erik Vinge; Brent R DeGeorge; Brent DeGeorge; J Kurt Chuprun; David M Harris; Erhe Gao; Andrea D Eckhart; Julie A Pitcher; Walter J Koch
Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(34):12457-62.
2008: Philip W Raake; Leif Erik Vinge; Erhe Gao; Matthieu Boucher; Giuseppe Rengo; Xiongwen Chen; Brent R DeGeorge; Scot Matkovich; Steven R Houser; Patrick Most; Andrea D Eckhart; Gerald W Dorn; Walter J Koch
G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.
Circulation research 2008;103(4):413-22.
2008: Matthieu Boucher; Stéphanie Pesant; Yong Hong Lei; Natasha Nanton; Patrick Most; Andrea D Eckhart; Walter J Koch; Erhe Gao
Simultaneous administration of insulin-like growth factor-1 and darbepoetin alfa protects the rat myocardium against myocardial infarction and enhances angiogenesis.
Clinical and translational science 2008;1(1):13-20.
2008: Brent R DeGeorge; Erhe Gao; Matthieu Boucher; Leif E Vinge; Jeffrey S Martini; Philip W Raake; J Kurt Chuprun; David M Harris; Gilbert W Kim; Stephen Soltys; Andrea D Eckhart; Walter J Koch
Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress.
Circulation 2008;117(11):1378-87.
2008: Aihua Hu; Xiangying Jiao; Erhe Gao; Yonghai Li; Said Sharifi-Azad; Zvi Grunwald; Xin L Ma; Jian-Zhong Sun
Tonic beta-adrenergic drive provokes proinflammatory and proapoptotic changes in aging mouse heart.
Rejuvenation research 2008;11(1):215-26.
2007: Hangxiang Zhang; Ling Tao; Xiangying Jiao; Erhe Gao; Bernard L Lopez; Theodore A Christopher; Walter J Koch; Xin L Ma
Nitrative thioredoxin inactivation as a cause of enhanced myocardial ischemia/reperfusion injury in the aging heart.
Free radical biology & medicine 2007;43(1):39-47.
2007: Erhe Gao; Matthieu Boucher; J Kurt Chuprun; Rui-Hai Zhou; Andrea D Eckhart; Walter J Koch
Darbepoetin alfa, a long-acting erythropoietin analog, offers novel and delayed cardioprotection for the ischemic heart.
American journal of physiology. Heart and circulatory physiology 2007;293(1):H60-8.
2007: Sven T Pleger; Patrick Most; Matthieu Boucher; Stephen Soltys; J Kurt Chuprun; Wiebke Pleger; Erhe Gao; Abhijit Dasgupta; Giuseppe Rengo; Andrew Remppis; Hugo A Katus; Andrea D Eckhart; Joseph E Rabinowitz; Walter J Koch
Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue.
Circulation 2007;115(19):2506-15.
2007: Ling Tao; Erhe Gao; Xiangying Jiao; Yuexing Yuan; Shuzhuang Li; Theodore A Christopher; Bernard L Lopez; Walter J Koch; Lawrence Chan; Barry J Goldstein; Xin L Ma
Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress.
Circulation 2007;115(11):1408-16.
2006: Ling Tao; Erhe Gao; Aihua Hu; C Coletti; Y Wang; Theodore A Christopher; Bernard L Lopez; Walter J Koch; Xin L Ma
Thioredoxin reduces post-ischemic myocardial apoptosis by reducing oxidative/nitrative stress.
British journal of pharmacology 2006;149(3):311-8.
2006: Ling Tao; Xiangying Jiao; Erhe Gao; Wayne B Lau; Yuexing Yuan; Bernard Lopez; Theodore A Christopher; Satish P RamachandraRao; William Williams; Garry J Southan; Kumar Sharma; Walter J Koch; Xin L Ma
Nitrative inactivation of thioredoxin-1 and its role in postischemic myocardial apoptosis.
Circulation 2006;114(13):1395-402.
2006: Patrick Most; Hanna Seifert; Erhe Gao; Hajime Funakoshi; Mirko Völkers; Jörg Heierhorst; Andrew Remppis; Sven T Pleger; Brent R DeGeorge; Andrea D Eckhart; Arthur M Feldman; Walter J Koch
Cardiac S100A1 protein levels determine contractile performance and propensity toward heart failure after myocardial infarction.
Circulation 2006;114(12):1258-68.
2006: Aihua Hu; Xiangying Jiao; Erhe Gao; Walter J Koch; Said Sharifi-Azad; Zvi Grunwald; Xin L Ma; Jian-Zhong Sun
Chronic beta-adrenergic receptor stimulation induces cardiac apoptosis and aggravates myocardial ischemia/reperfusion injury by provoking inducible nitric-oxide synthase-mediated nitrative stress.
The Journal of pharmacology and experimental therapeutics 2006;318(2):469-75.
2005: Sven T Pleger; Andrew Remppis; Beatrix Heidt; Mirko Völkers; J Kurt Chuprun; Matthew Kuhn; Rui-Hai Zhou; Erhe Gao; Gabor Szabo; Dieter Weichenhan; Oliver J Müller; Andrea D Eckhart; Hugo A Katus; Walter J Koch; Patrick Most
S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(6):1120-9.
2005: Erhe Gao; Justin L Kaplan; Michelle S Victain; William C Dalsey; Lawrence de Garavilla
Adenosine A1 antagonism attenuates beta-adrenergic-resistant sudden hypoxic cardiac insufficiency.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2005;12(5):389-95.
2005: Hui-Rong Liu; Erhe Gao; Aihua Hu; Ling Tao; Yan Qu; Patrick Most; Walter J Koch; Theodore A Christopher; Bernard L Lopez; Emad S Alnemri; Antonis S Zervos; Xin L Ma
Role of Omi/HtrA2 in apoptotic cell death after myocardial ischemia and reperfusion.
Circulation 2005;111(1):90-6.
2004: F Gao; L Tao; W Yan; Erhe Gao; Hui-Rong Liu; Bernard L Lopez; Theodore A Christopher; Xin L Ma
Early anti-apoptosis treatment reduces myocardial infarct size after a prolonged reperfusion.
Apoptosis : an international journal on programmed cell death 2004;9(5):553-9.
2004: Rosanna Botta; Erhe Gao; Giorgio Stassi; Désirée Bonci; Elvira Pelosi; Donna Zwas; Mariella Patti; Lucrezia Colonna; Marta Baiocchi; Simona Coppola; Xin Ma; Gianluigi Condorelli; Cesare Peschle
Heart infarct in NOD-SCID mice: therapeutic vasculogenesis by transplantation of human CD34+ cells and low dose CD34+KDR+ cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(12):1392-4.
2004: Ling Tao; Erhe Gao; Nathan S Bryan; Yan Qu; Hui-Rong Liu; Aihua Hu; Theodore A Christopher; Bernard L Lopez; Junji Yodoi; Walter J Koch; Martin Feelisch; Xin L Ma
Cardioprotective effects of thioredoxin in myocardial ischemia and reperfusion: role of S-nitrosation [corrected].
Proceedings of the National Academy of Sciences of the United States of America 2004;101(31):11471-6.
2004: Hui-Rong Liu; Feng Gao; Ling Tao; Wen-Li Yan; Erhe Gao; Theodore A Christopher; Bernard L Lopez; Aihua Hu; Xin L Ma
Antiapoptotic mechanisms of benidipine in the ischemic/reperfused heart.
British journal of pharmacology 2004;142(4):627-34.
2004: Feng Liang; Erhe Gao; Ling Tao; Huirong Liu; Yan Qu; Theodore A Christopher; Bernard L Lopez; Xin L Ma
Critical timing of L-arginine treatment in post-ischemic myocardial apoptosis-role of NOS isoforms.
Cardiovascular research 2004;62(3):568-77.
2004: Hui-Rong Liu; Ling Tao; Erhe Gao; Bernard L Lopez; Theodore A Christopher; Robert N Willette; Eliot ohlstein; Tian-Li Yue; Xin L Ma
Anti-apoptotic effects of rosiglitazone in hypercholesterolemic rabbits subjected to myocardial ischemia and reperfusion.
Cardiovascular research 2004;62(1):135-44.
2003: Ling Tao; Hui-Rong Liu; Erhe Gao; Zhi-Ping Teng; Bernard L Lopez; Theodore A Christopher; Xin L Ma; Ines Batinic-Haberle; Robert N Willette; Eliot ohlstein; Tian-Li Yue
Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia.
Circulation 2003;108(22):2805-11.
2003: Takeshi Tsuda; Erhe Gao; Lucia Evangelisti; Dessislava Markova; Xinliang Ma; Mon-Li Chu
Post-ischemic myocardial fibrosis occurs independent of hemodynamic changes.
Cardiovascular research 2003;59(4):926-33.
2003: Justin L Kaplan; Erhe Gao; Lawrence de Garavilla; Michelle S Victain; Bohdan Minczak; William C Dalsey
Adenosine A1 antagonism attenuates atropine-resistant hypoxic bradycardia in rats.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2003;10(9):923-30.
2002: Theodore A Christopher; Bernard L Lopez; Jason C Stillwagon; Feng Gao; Erhe Gao; Xin L Ma; Eliot ohlstein; Tian-Li Yue
Idoxifene causes endothelium-dependent, nitric oxide-mediated vasorelaxation in male rats.
European journal of pharmacology 2002;446(1-3):139-43.
2002: Feng Gao; Chen-Lin Yao; Erhe Gao; Qi-Zhong Mo; Wen-Li Yan; Richard McLaughlin; Bernard L Lopez; Theodore A Christopher; Xin L Ma
Enhancement of glutathione cardioprotection by ascorbic acid in myocardial reperfusion injury.
The Journal of pharmacology and experimental therapeutics 2002;301(2):543-50.
2002: Feng Gao; Erhe Gao; Tian-Li Yue; Eliot ohlstein; Bernard L Lopez; Theodore A Christopher; Xin L Ma
Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation.
Circulation 2002;105(12):1497-502.
2001: Erhe Gao; Justin L Kaplan; Y Shi; Michelle S Victain; William C Dalsey; Lawrence de Garavilla
Adenosine A1 receptor antagonist prolongs survival in the hypoxic rat.
Journal of cardiovascular pharmacology 2001;38(3):384-94.
2000: J Cummings; Justin L Kaplan; Erhe Gao; D Clas; William C Dalsey; Lawrence de Garavilla
Antagonism of the cardiodepressant effects of adenosine during acute hypoxia.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2000;7(6):618-24.
1999: J Xu; F Gao; X L Ma; Erhe Gao; E Friedman; David L Snyder; J Horwitz; A Pelleg
Effect of aging on the negative chronotropic and anti-beta-adrenergic actions of adenosine in the rat heart.
Journal of cardiovascular pharmacology 1999;34(6):904-12.
1998: GL Liu; Theodore A Christopher; Bernard L Lopez; Feng Gao; Y Guo; Erhe Gao; K Knuettel; M Feelisch; Xin L Ma
SP/W-5186, A cysteine-containing nitric oxide donor, attenuates postischemic myocardial injury.
The Journal of pharmacology and experimental therapeutics 1998;287(2):527-37.
1998: Erhe Gao; David L Snyder; Jay Roberts; E Friedman; G Cai; A Pelleg; J Horwitz
Age-related decline in beta adrenergic and adenosine A1 receptor function in the heart are attenuated by dietary restriction.
The Journal of pharmacology and experimental therapeutics 1998;285(1):186-92.
1997: G Cai; H Y Wang; Erhe Gao; J Horwitz; David L Snyder; A Pelleg; Jay Roberts; E Friedman
Reduced adenosine A1 receptor and G alpha protein coupling in rat ventricular myocardium during aging.
Circulation research 1997;81(6):1065-71.
1997: Erhe Gao; David L Snyder; M D Johnson; E Friedman; Jay Roberts; J Horwitz
The effect of age on adenosine A1 receptor function in the rat heart.
Journal of molecular and cellular cardiology 1997;29(2):593-602.