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Pedro Majano

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María Luisa Pérez-Lozano; Angela Rynne-Vidal; José A Sánchez-Tomero; Pilar Sandoval; Rafael Selgas; Abelardo Aguilera; Patricia Albar-Vizcaíno; José Antonio Jiménez-Heffernan; Pedro Majano; Manuel López-Cabrera
Functional Relevance of the Switch of VEGF Receptors/Co-Receptors during Peritoneal Dialysis-Induced Mesothelial to Mesenchymal Transition.
Ignacio Benedicto; Luisa García-Buey; Virgínia Gondar; Manuel López-Cabrera; Francisca Molina-Jiménez; Ricardo Moreno-Otero; Pedro Majano
Role of tight junctions in hepatitis C virus infection.
Francisca Molina-Jimenez; Ricardo Moreno-Otero; Jose J Marin; Rafael Aldabe; Thomas F Baumert; Ignacio Benedicto; Oscar Briz; François-Loïc Cosset; Viet Loan Dao Thi; Virginia Gondar; Dimitri Lavillette; Manuel Lopez-Cabrera; Pedro Majano
Matrigel-embedded 3D culture of Huh-7 cells as a hepatocyte-like polarized system to study hepatitis C virus cycle.

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All Publications

2013: María Luisa Pérez-Lozano; Angela Rynne-Vidal; José A Sánchez-Tomero; Pilar Sandoval; Rafael Selgas; Abelardo Aguilera; Patricia Albar-Vizcaíno; José Antonio Jiménez-Heffernan; Pedro Majano; Manuel López-Cabrera
Functional Relevance of the Switch of VEGF Receptors/Co-Receptors during Peritoneal Dialysis-Induced Mesothelial to Mesenchymal Transition.
PloS one 2013;8(4):e60776.
2012: Ignacio Benedicto; Luisa García-Buey; Virgínia Gondar; Manuel López-Cabrera; Francisca Molina-Jiménez; Ricardo Moreno-Otero; Pedro Majano
Role of tight junctions in hepatitis C virus infection.
Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva 2012;104(5):255-63.
2012: Francisca Molina-Jimenez; Ricardo Moreno-Otero; Jose J Marin; Rafael Aldabe; Thomas F Baumert; Ignacio Benedicto; Oscar Briz; François-Loïc Cosset; Viet Loan Dao Thi; Virginia Gondar; Dimitri Lavillette; Manuel Lopez-Cabrera; Pedro Majano
Matrigel-embedded 3D culture of Huh-7 cells as a hepatocyte-like polarized system to study hepatitis C virus cycle.
Virology 2012;425(1):31-9.
2011: Jesús Loureiro; Pedro Majano; María Luisa Pérez-Lozano; Fernando Rodríguez-Pascual; Vicente Ruiz-Carpio; Pilar Sandoval; Rafael Selgas; Abelardo Aguilera; Patricia Albar-Vizcaíno; Francisco Borras-Cuesta; Javier Dotor; Santiago Lamas; Manuel López-Cabrera
Blocking TGF-β1 protects the peritoneal membrane from dialysate-induced damage.
Journal of the American Society of Nephrology : JASN 2011;22(9):1682-95.
2011: Ignacio Benedicto; Manuel López-Cabrera; Francisca Molina-Jiménez; Ricardo Moreno-Otero; Pedro Majano
Interplay among cellular polarization, lipoprotein metabolism and hepatitis C virus entry.
World journal of gastroenterology : WJG 2011;17(22):2683-90.
2010: Francisca Molina-Jiménez; Ignacio Benedicto; Miki Murata; Samuel Martín-Vílchez; Toshihito Seki; José Antonio Pintor-Toro; María Tortolero; Ricardo Moreno-Otero; Kazuichi Okazaki; Kazuhiko Koike; José Luchi Barbero; Koichi Matsuzaki; Pedro Majano; Manuel López-Cabrera
Expression of pituitary tumor-transforming gene 1 (PTTG1)/securin in hepatitis B virus (HBV)-associated liver diseases: evidence for an HBV X protein-mediated inhibition of PTTG1 ubiquitination and degradation.
Hepatology (Baltimore, Md.) 2010;51(3):777-87.
2009: Ignacio Benedicto; Francisca Molina-Jiménez; Birke Bartosch; François-Loïc Cosset; Dimitri Lavillette; Jesús Prieto; Ricardo Moreno-Otero; Agustín Valenzuela-Fernández; Rafael Aldabe; Manuel López-Cabrera; Pedro Majano
The tight junction-associated protein occludin is required for a postbinding step in hepatitis C virus entry and infection.
Journal of virology 2009;83(16):8012-20.
2009: Natalia Dionisio; Maria V Garcia-Mediavilla; Sonia Sanchez-Campos; Pedro Majano; Ignacio Benedicto; Juan A Rosado; Gines M Salido; Javier González-Gallego
Hepatitis C virus NS5A and core proteins induce oxidative stress-mediated calcium signalling alterations in hepatocytes.
Journal of hepatology 2009;50(5):872-82.
2008: Ignacio Benedicto; Francisca Molina-Jiménez; Olga Barreiro; Alejandra Maldonado-Rodríguez; Jesús Prieto; Ricardo Moreno-Otero; Rafael Aldabe; Manuel López-Cabrera; Pedro Majano
Hepatitis C virus envelope components alter localization of hepatocyte tight junction-associated proteins and promote occludin retention in the endoplasmic reticulum.
Hepatology (Baltimore, Md.) 2008;48(4):1044-53.
2008: Samuel Martín-Vílchez; Paloma Sanz-Cameno; Yolanda Rodríguez-Muñoz; Pedro Majano; Francisca Molina-Jiménez; Manuel López-Cabrera; Ricardo Moreno-Otero; Enrique Lara-Pezzi
The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells.
Hepatology (Baltimore, Md.) 2008;47(6):1872-83.
2008: S Martín-Vilchez; F Molina-Jiménez; J L Alonso-Lebrero; P Sanz-Cameno; Y Rodríguez-Muñoz; I Benedicto; P Roda-Navarro; María Trapero-Marugán; L Aragoneses-Fenoll; S González; J P Pivel; A L Corbí; M López-Cabrera; R Moreno-Otero; Pedro Majano
AM3, a natural glycoconjugate, induces the functional maturation of human dendritic cells.
British journal of pharmacology 2008;154(3):698-708.
2007: Susana Ovalle; María Dolores Gutiérrez-López; Nieves Olmo; Javier Turnay; M Antonia Lizarbe; Pedro Majano; Francisca Molina-Jiménez; Manuel López-Cabrera; María Yáñez-Mó; Francisco Sánchez-Madrid; Carlos Cabañas
The tetraspanin CD9 inhibits the proliferation and tumorigenicity of human colon carcinoma cells.
International journal of cancer. Journal international du cancer 2007;121(10):2140-52.
2006: L Gombau; F García; Agustin Lahoz; Myriam Fabre; Pedro Roda-Navarro; Pedro Majano; José Luis Alonso-Lebrero; Juan Pablo Pivel; José V Castell; M J Gómez-Lechon; Salvador González
Polypodium leucotomos extract: antioxidant activity and disposition.
Toxicology in vitro : an international journal published in association with BIBRA 2006;20(4):464-71.
2005: María V García-Mediavilla; Sonia Sánchez-Campos; Pilar González-Pérez; Marta Gómez-Gonzalo; Pedro Majano; Manuel López-Cabrera; Gerardo Clemente; Carmelo García-Monzón; Javier González-Gallego
Differential contribution of hepatitis C virus NS5A and core proteins to the induction of oxidative and nitrosative stress in human hepatocyte-derived cells.
Journal of hepatology 2005;43(4):606-13.
2005: Pedro Majano; José Luis Alonso-Lebrero; Agnieszka Janczyk; Samuel Martín-Vichez; Francisca Molina-Jiménez; Aurora Brieva; Juan Pablo Pivel; Salvador González; Manuel López-Cabrera; Ricardo Moreno-Otero
AM3 inhibits LPS-induced iNOS expression in mice.
International immunopharmacology 2005;5(7-8):1165-70.
2005: Arantxa Apolinario; Pedro Majano; R Lorente; Oscar Núñez; Gerardo Clemente; Carmelo García-Monzón
Gene expression profile of T-cell-specific chemokines in human hepatocyte-derived cells: evidence for a synergistic inducer effect of cytokines and hepatitis C virus proteins.
Journal of viral hepatitis 2005;12(1):27-37.
2004: Oscar Núñez; Amalia Fernández-Martínez; Pedro Majano; Arantxa Apolinario; Marta Gómez-Gonzalo; Ignacio Benedicto; Manuel López-Cabrera; Lisardo Boscá; Gerardo Clemente; Carmelo García-Monzón; Paloma Martín-Sanz
Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins.
Gut 2004;53(11):1665-72.
2004: María-Encarnación Fernández-Contreras; Beatriz Jiménez De Ayala; María-Luisa García De Paredes; Amalia Velasco; Pedro Majano; José Palacios; Carlos Gamallo
Thymidylate synthase expression pattern is a prognostic factor in patients of colorectal cancer treated with 5-fluorouracil.
International journal of oncology 2004;25(4):877-85.
2004: Pedro Majano; Pedro Roda-Navarro; José Luis Alonso-Lebrero; Aurora Brieva; Cristina Casal; Juan Pablo Pivel; Manuel López-Cabrera; Ricardo Moreno-Otero
AM3 inhibits HBV replication through activation of peripheral blood mononuclear cells.
International immunopharmacology 2004;4(7):921-7.
2004: Pedro Majano; Jesús Medina; Itxaso Zubía; Lourdes Sunyer; Enrique Lara-Pezzi; Alejandra Maldonado-Rodríguez; Manuel López-Cabrera; Ricardo Moreno-Otero
N-Acetyl-cysteine modulates inducible nitric oxide synthase gene expression in human hepatocytes.
Journal of hepatology 2004;40(4):632-7.
2004: Arantxa Apolinario; Moisés Diago; Oreste Lo Iacono; R Lorente; C Pérez; Pedro Majano; Gerardo Clemente; Carmelo García-Monzón
Increased circulating and intrahepatic T-cell-specific chemokines in chronic hepatitis C: relationship with the type of virological response to peginterferon plus ribavirin combination therapy.
Alimentary pharmacology & therapeutics 2004;19(5):551-62.
2003: Jesús Medina; Luis Caveda; Paloma Sanz-Cameno; Alicia G Arroyo; Samuel Martín-Vílchez; Pedro Majano; Luisa García-Buey; Francisco Sánchez-Madrid; Ricardo Moreno-Otero
Hepatocyte growth factor activates endothelial proangiogenic mechanisms relevant in chronic hepatitis C-associated neoangiogenesis.
Journal of hepatology 2003;38(5):660-7.
2003: Juan J Díaz-Gil; Pedro Majano; Manuel López-Cabrera; Vicente Sánchez-López; Carmen Rúa; Celia Machín; Carolina Trilla; Rafael García-Cañero; Ricardo Moreno-Otero
The mitogenic activity of the liver growth factor is mediated by tumor necrosis factor alpha in rat liver.
Journal of hepatology 2003;38(5):598-604.
2003: Pedro Majano; Carmelo Garcia-Monzon
Does nitric oxide play a pathogenic role in hepatitis C virus infection?
Cell death and differentiation 2003;10 Suppl 1():S13-5.
2002: Arantxa Apolinario; Pedro Majano; Eduardo Alvarez-Pérez; Alicia Saez; Carlos Lozano; Javier Vargas; Carmelo García-Monzón
Increased expression of T cell chemokines and their receptors in chronic hepatitis C: relationship with the histological activity of liver disease.
The American journal of gastroenterology 2002;97(11):2861-70.
2001: Pedro Majano; Carmelo García-Monzón; Elena R García-Trevijano; Fernando J Corrales; J Cámara; P Ortiz; José M Mato; Matías A Avila; Ricardo Moreno-Otero
S-Adenosylmethionine modulates inducible nitric oxide synthase gene expression in rat liver and isolated hepatocytes.
Journal of hepatology 2001;35(6):692-9.
2001: Pedro Majano; Enrique Lara-Pezzi; Manuel López-Cabrera; Arantxa Apolinario; Ricardo Moreno-Otero; Carmelo García-Monzón
Hepatitis B virus X protein transactivates inducible nitric oxide synthase gene promoter through the proximal nuclear factor kappaB-binding site: evidence that cytoplasmic location of X protein is essential for gene transactivation.
Hepatology (Baltimore, Md.) 2001;34(6):1218-24.
2001: Marian Mellen; Esther Larrea; Iosu Sola; Pedro Majano; C Jiménez; Maria Pilar Civeira; Jesús Prieto
Nuclear factor-kappa B in the liver of patients with chronic hepatitis C: decreased RelA expression is associated with enhanced fibrosis progression.
Hepatology (Baltimore, Md.) 2001;34(5):1041-8.
2001: Enrique Lara-Pezzi; Pedro Majano; María Yáñez-Mó; Marta Gómez-Gonzalo; Marta Carretero; Ricardo Moreno-Otero; Francisco Sánchez-Madrid; Manuel López-Cabrera
Effect of the hepatitis B virus HBx protein on integrin-mediated adhesion to and migration on extracellular matrix.
Journal of hepatology 2001;34(3):409-15.
2001: M Romero; Carmelo García-Monzón; Gerardo Clemente; M Salcedo; E Alvarez; Pedro Majano; Ricardo Moreno-Otero
Intrahepatic expression of inducible nitric oxide synthase in acute liver allograft rejection: evidence of modulation by corticosteroids.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2001;7(1):16-21.
2000: Carmelo García-Monzón; E Martín-Pérez; OL Iacono; Miguel Fernández-Bermejo; Pedro Majano; Arantxa Apolinario; E Larrañaga; Ricardo Moreno-Otero
Characterization of pathogenic and prognostic factors of nonalcoholic steatohepatitis associated with obesity.
Journal of hepatology 2000;33(5):716-24.
2000: Carmelo García-Monzón; Pedro Majano; I Zubia; P Sanz; Arantxa Apolinario; Ricardo Moreno-Otero
Intrahepatic accumulation of nitrotyrosine in chronic viral hepatitis is associated with histological severity of liver disease.
Journal of hepatology 2000;32(2):331-8.
1998: Enrique Lara-Pezzi; Angel L Armesilla; Pedro Majano; Juan Miguel Redondo; Manuel López-Cabrera
The hepatitis B virus X protein activates nuclear factor of activated T cells (NF-AT) by a cyclosporin A-sensitive pathway.
The EMBO journal 1998;17(23):7066-77.
1998: Enrique Lara-Pezzi; Pedro Majano; Marta Gómez-Gonzalo; Carmelo García-Monzón; Ricardo Moreno-Otero; M Levrero; Manuel López-Cabrera
The hepatitis B virus X protein up-regulates tumor necrosis factor alpha gene expression in hepatocytes.
Hepatology (Baltimore, Md.) 1998;28(4):1013-21.
1998: Carmelo García-Monzón; Pedro Majano; JA Solís; S Rodríguez; Francisco Colina; Miguel López-Botet; Enrique Moreno-González; Ricardo Moreno-Otero
Intrahepatic enhanced expression of beta2-microglobulin conformational epitope in acute liver allograft rejection: evidence of modulation by glucocorticoids.
Digestive diseases and sciences 1998;43(8):1755-62.
1998: Pedro Majano; Carmelo García-Monzón; Manuel López-Cabrera; Enrique Lara-Pezzi; Elena Fernández-Ruiz; C García-Iglesias; María J Borque; Ricardo Moreno-Otero
Inducible nitric oxide synthase expression in chronic viral hepatitis. Evidence for a virus-induced gene upregulation.
The Journal of clinical investigation 1998;101(7):1343-52.
1995: Carmelo Garcia-Monzon; Luisa Garcia-Buey; Pedro Majano; Ricardo Moreno-Otero
Integrins: structure, biological functions and relevance in viral chronic hepatitis.
European journal of clinical investigation 1995;25(2):71-8.