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Rajat Singh

Research Profile

Physiology

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Publications

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Fnu Nagajyothi; Jeffrey E Pessin; Philipp E Scherer; Gary J Schwartz; Rajat Singh; Louis M Weiss; Dazhi Zhao; Chris Albanese; Mahalia S Desruisseaux; Stephen M Factor; Huan Huang; Regina Kuliawat; Christine M Kusminski; Feng Li; Michael P Lisanti; Fabiana S Machado; Herbert B Tanowitz
Alterations in glucose homeostasis in a murine model of Chagas disease.
Susmita Kaushik; Hyok Joon Kwon; Nuria Martinez Lopez; Jeffrey Pessin; Srabani Sahu; Gary J Schwartz; Esperanza Arias; Diana Athonvarangkul; Rajat Singh
Loss of autophagy in hypothalamic POMC neurons impairs lipolysis.
Eijiro Yamada; Rajat Singh
Mapping autophagy on to your metabolic radar.

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All Publications

2013: Fnu Nagajyothi; Jeffrey E Pessin; Philipp E Scherer; Gary J Schwartz; Rajat Singh; Louis M Weiss; Dazhi Zhao; Chris Albanese; Mahalia S Desruisseaux; Stephen M Factor; Huan Huang; Regina Kuliawat; Christine M Kusminski; Feng Li; Michael P Lisanti; Fabiana S Machado; Herbert B Tanowitz
Alterations in glucose homeostasis in a murine model of Chagas disease.
The American journal of pathology 2013;182(3):886-94.
2012: Susmita Kaushik; Hyok Joon Kwon; Nuria Martinez Lopez; Jeffrey Pessin; Srabani Sahu; Gary J Schwartz; Esperanza Arias; Diana Athonvarangkul; Rajat Singh
Loss of autophagy in hypothalamic POMC neurons impairs lipolysis.
EMBO reports 2012;13(3):258-65.
2012: Eijiro Yamada; Rajat Singh
Mapping autophagy on to your metabolic radar.
Diabetes 2012;61(2):272-80.
2012: Rajat Singh; Ana Maria Cuervo
Lipophagy: connecting autophagy and lipid metabolism.
International journal of cell biology 2012;2012():282041.
2011: Rajat Singh
Hypothalamic lipophagy and energetic balance.
Aging 2011;3(10):934-42.
2011: Susmita Kaushik; Roberta Kiffin; Jose Antonio Rodriguez-Navarro; Srabani Sahu; Gary J Schwartz; Esperanza Arias; Ana Maria Cuervo; Rajat Singh
Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance.
Cell metabolism 2011;14(2):173-83.
2011: Rajat Singh; Ana Maria Cuervo
Autophagy in the cellular energetic balance.
Cell metabolism 2011;13(5):495-504.
2010: Vanessa M Hubbard; Rut Valdor; Bindi Patel; Rajat Singh; Ana Maria Cuervo; Fernando Macian-Juan
Macroautophagy regulates energy metabolism during effector T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(12):7349-57.
2010: Yongjun Wang; Rajat Singh; Youqing Xiang; Linda E Greenbaum; Mark J Czaja
Nuclear factor κB up-regulation of CCAAT/enhancer-binding protein β mediates hepatocyte resistance to tumor necrosis factor α toxicity.
Hepatology (Baltimore, Md.) 2010;52(6):2118-26.
2010: S Kaushik; Rajat Singh; Ana Maria Cuervo
Autophagic pathways and metabolic stress.
Diabetes, obesity & metabolism 2010;12 Suppl 2():4-14.
2010: Yongjun Wang; Rajat Singh; Youqing Xiang; Mark J Czaja
Macroautophagy and chaperone-mediated autophagy are required for hepatocyte resistance to oxidant stress.
Hepatology (Baltimore, Md.) 2010;52(1):266-77.
2010: Rajat Singh
Autophagy and regulation of lipid metabolism.
Results and problems in cell differentiation 2010;52():35-46.
2009: Rajat Singh; Yongjun Wang; Jörn M Schattenberg; Youqing Xiang; Mark J Czaja
Chronic oxidative stress sensitizes hepatocytes to death from 4-hydroxynonenal by JNK/c-Jun overactivation.
American journal of physiology. Gastrointestinal and liver physiology 2009;297(5):G907-17.
2009: Rajat Singh; Youqing Xiang; Yongjun Wang; Kiran Baikati; Ana Maria Cuervo; Yen K Luu; Yan Tang; Jeffrey Pessin; Gary J Schwartz; Mark J Czaja
Autophagy regulates adipose mass and differentiation in mice.
The Journal of clinical investigation 2009;119(11):3329-39.
2009: Rajat Singh; Susmita Kaushik; Yongjun Wang; Youqing Xiang; Inna Novak; Masaaki Komatsu; Keiji Tanaka; Ana Maria Cuervo; Mark J Czaja
Autophagy regulates lipid metabolism.
Nature 2009;458(7242):1131-5.
2009: Rajat Singh; Yongjun Wang; Youqing Xiang; Kathryn Tanaka; William A Gaarde; Mark J Czaja
Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance.
Hepatology (Baltimore, Md.) 2009;49(1):87-96.
2008: Rajat Singh; Mark J Czaja
Compensatory mechanisms and the type of injury determine the fate of cells with impaired macroautophagy.
Autophagy 2008;4(4):516-8.
2008: Yongjun Wang; Rajat Singh; Ashish C Massey; Saul S Kane; Susmita Kaushik; Taneisha Grant; Youqing Xiang; Ana Maria Cuervo; Mark J Czaja
Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus.
The Journal of biological chemistry 2008;283(8):4766-77.
2007: Rajat Singh; Mark J Czaja
Regulation of hepatocyte apoptosis by oxidative stress.
Journal of gastroenterology and hepatology 2007;22 Suppl 1():S45-8.
2006: Yongjun Wang; Rajat Singh; Jay H Lefkowitch; Raina M Rigoli; Mark J Czaja
Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathway.
The Journal of biological chemistry 2006;281(22):15258-67.
2006: Jörn M Schattenberg; Rajat Singh; Yongjun Wang; Jay H Lefkowitch; Raina M Rigoli; Philipp E Scherer; Mark J Czaja
JNK1 but not JNK2 promotes the development of steatohepatitis in mice.
Hepatology (Baltimore, Md.) 2006;43(1):163-72.
2005: Rajat Singh; Mark J Czaja
Capitalizing on AKT signaling to inhibit hepatocellular carcinoma cell proliferation.
Cancer biology & therapy 2005;4(12):1419-21.
2005: Jörn M Schattenberg; Yongjun Wang; Rajat Singh; Raina M Rigoli; Mark J Czaja
Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling.
The Journal of biological chemistry 2005;280(11):9887-94.