FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Kevin Tracey

Research Profile

Chemicals & Drugs

Living Beings

Disorders

Anatomy

Physiology

Signal Transduction

Co-author Network

Publications

TOP 3
Colin Reardon; Mauricio Rosas-Ballina; Kevin Tracey; Michael W Tusche; Peder S Olofsson; Peder Olofsson; Dirk Brenner; Anne Brüstle; Gordon S Duncan; Tak W Mak
Lymphocyte-derived ACh regulates local innate but not adaptive immunity.
Ulf Andersson; Kevin Tracey
Neural reflexes in inflammation and immunity.
Kevin Tracey
Immune cells exploit a neural circuit to enter the CNS.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Kevin Tracey (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Colin Reardon; Mauricio Rosas-Ballina; Kevin Tracey; Michael W Tusche; Peder S Olofsson; Peder Olofsson; Dirk Brenner; Anne Brüstle; Gordon S Duncan; Tak W Mak
Lymphocyte-derived ACh regulates local innate but not adaptive immunity.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(4):1410-5.
2012: Ulf Andersson; Kevin Tracey
Neural reflexes in inflammation and immunity.
The Journal of experimental medicine 2012;209(6):1057-68.
2012: Kevin Tracey
Immune cells exploit a neural circuit to enter the CNS.
Cell 2012;148(3):392-4.
2012: Ulf Andersson; Kevin Tracey
Reflex principles of immunological homeostasis.
Annual review of immunology 2012;30():313-35.
2012: Peder S Olofsson; Valentin A Pavlov; Mauricio Rosas-Ballina; Kevin Tracey; Sergio I Valdés-Ferrer; David A Katz; Yaakov A Levine; Mahendar Ochani; Sangeeta S Chavan
α7 nicotinic acetylcholine receptor (α7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex.
Molecular medicine (Cambridge, Mass.) 2012;18():539-43.
2012: Huan Yang; Yousef Al-Abed; Ulf Andersson; Marco E Bianchi; Helena Erlandsson Harris; Peter Lundbäck; Lars Ottosson; Kevin Tracey; Emilie Venereau; Daniel J Antoine
Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1).
Molecular medicine (Cambridge, Mass.) 2012;18():250-9.
2012: Mark C Dessing; Peter P Nawroth; Huan Yang; Gwendoline J Teske; Angelika Bierhaus; Wilco P Pulskens; Tom van der Poll; Sandrine Florquin; Loes M Butter; Kevin Tracey; Jaklien C Leemans
RAGE does not contribute to renal injury and damage upon ischemia/reperfusion-induced injury.
Journal of innate immunity 2012;4(1):80-5.
2011: Mauricio Rosas-Ballina; Michael W Tusche; Sergio I Valdés-Ferrer; Ulf Andersson; Sangeeta Chavan; Yaakov A Levine; Tak W Mak; Mahendar Ochani; Peder S Olofsson; Valentin A Pavlov; Colin Reardon; Kevin Tracey
Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit.
Science (New York, N.Y.) 2011;334(6052):98-101.
2011: Betty Diamond; Patricio T Huerta; Kevin Tracey; Bruce T Volpe
It takes guts to grow a brain: Increasing evidence of the important role of the intestinal microflora in neuro- and immune-modulatory functions during development and adulthood.
BioEssays : news and reviews in molecular, cellular and developmental biology 2011;33(8):588-91.
2011: Yousef Al-Abed; Christine N Metz; Kai Fan Cheng; Bayan Aljabari; Sonya Vanpatten; Steven Blau; Hans Lee; Mahendar Ochani; Valentin A Pavlov; Thomas Coleman; Nathanlie Meurice; Kevin Tracey; Edmund J Miller
Thyroxine is a potential endogenous antagonist of macrophage migration inhibitory factor (MIF) activity.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(20):8224-7.
2011: Kevin Tracey
Cell biology. Ancient neurons regulate immunity.
Science (New York, N.Y.) 2011;332(6030):673-4.
2011: Wei Li; Shu Zhu; Jianhua Li; Andrei Assa; Arvin Jundoria; Jianying Xu; Saijun Fan; N Tony Eissa; Kevin Tracey; Andrew E Sama; Haichao Wang
EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages.
Biochemical pharmacology 2011;81(9):1152-63.
2011: Greg J Norman; John S Morris; kate karelina; Zachary Weil; Ning Zhang; Yousef Al-Abed; Holly M Brothers; Gary L Wenk; Valentin A Pavlov; Kevin Tracey; A Courtney DeVries
Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(9):3446-52.
2011: Betty Diamond; Kevin Tracey
Mapping the immunological homunculus.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(9):3461-2.
2011: Sanjaya K Satapathy; Kevin Tracey; Sergio I Valdes-Ferrer; Mauricio Rosas-Ballina; Jesse Roth; Sangeeta Chavan; Meghan Dancho; Yael Tobi Harris; Laqueta K Hudson; Mahendar Ochani; Peder S Olofsson; Valentin A Pavlov
Galantamine alleviates inflammation and other obesity-associated complications in high-fat diet-fed mice.
Molecular medicine (Cambridge, Mass.) 2011;17(7-8):599-606.
2011: Wei Li; Shu Zhu; Jianhua Li; Yan Huang; Rongrong Zhou; Xuegong Fan; Huan Yang; Xing Gong; N Tony Eissa; Willi Jahnen-Dechent; Ping Wang; Kevin Tracey; Andrew E Sama; Haichao Wang
A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation.
PloS one 2011;6(2):e16945.
2011: Ulf Andersson; Kevin Tracey
HMGB1 is a therapeutic target for sterile inflammation and infection.
Annual review of immunology 2011;29():139-62.
2011: Ulf Andersson; Kevin Tracey
Molecular basis of applied biological therapeutics.
Journal of internal medicine 2011;269(1):2-7.
2011: J M Huston; Kevin Tracey
The pulse of inflammation: heart rate variability, the cholinergic anti-inflammatory pathway and implications for therapy.
Journal of internal medicine 2011;269(1):45-53.
2011: Annette Bruchfeld; Mårten Wendt; Johan Bratt; Abdul Rashid Qureshi; Sangeeta Chavan; Kevin Tracey; Karin Palmblad; Iva Gunnarsson
High-mobility group box-1 protein (HMGB1) is increased in antineutrophilic cytoplasmatic antibody (ANCA)-associated vasculitis with renal manifestations.
Molecular medicine (Cambridge, Mass.) 2011;17(1-2):29-35.
2010: Mohamed Lamkanfi; Anasuya Sarkar; Lieselotte Vande Walle; Alberto C Vitari; Amal O Amer; Mark D Wewers; Kevin Tracey; Thirumala-Devi Kanneganti; Vishva M Dixit
Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(7):4385-92.
2010: D Tang; R Kang; C-W Cheh; K M Livesey; Xiaoyan Liang; N E Schapiro; R Benschop; L J Sparvero; Andrew A Amoscato; Kevin Tracey; Herbert J Zeh; Michael T Lotze
HMGB1 release and redox regulates autophagy and apoptosis in cancer cells.
Oncogene 2010;29(38):5299-310.
2010: Daolin Tang; Rui Kang; Kristen M Livesey; Chun-Wei Cheh; Adam Farkas; Patricia A Loughran; George Hoppe; Marco E Bianchi; Kevin Tracey; Herbert J Zeh; Michael T Lotze
Endogenous HMGB1 regulates autophagy.
The Journal of cell biology 2010;190(5):881-92.
2010: Lisa C Loram; Jacqueline A Harrison; Lindsey Chao; Frederick R Taylor; Anireddy Reddy; Carissa L Travis; Rona Giffard; Yousef Al-Abed; Kevin Tracey; Steven F Maier; Linda R Watkins
Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats.
Brain, behavior, and immunity 2010;24(6):959-67.
2010: Kevin Tracey
Understanding immunity requires more than immunology.
Nature immunology 2010;11(7):561-4.
2010: Grace H Kim; Christopher P Kellner; Zachary L Hickman; Brad E Zacharia; Robert M Starke; Brian Y Hwang; Andrew F Ducruet; Luis Fernandez; STEPHAN MAYER; Kevin Tracey; E Sander Connolly
A phase I clinical trial of tiopronin, a putative neuroprotective agent, in aneurysmal subarachnoid hemorrhage.
Neurosurgery 2010;67(1):182-5; discussion 186.
2010: A Bruchfeld; R S Goldstein; S Chavan; N B Patel; M Rosas-Ballina; N Kohn; Abdul Rashid Qureshi; Kevin Tracey
Whole blood cytokine attenuation by cholinergic agonists ex vivo and relationship to vagus nerve activity in rheumatoid arthritis.
Journal of internal medicine 2010;268(1):94-101.
2010: Huan Yang; Hulda S Hreggvidsdottir; Karin Palmblad; Haichao Wang; Mahendar Ochani; Jianhua Li; Ben Lu; Sangeeta Chavan; Mauricio Rosas-Ballina; Yousef Al-Abed; Shizuo Akira; Angelika Bierhaus; Helena Erlandsson Harris; Ulf Andersson; Kevin Tracey
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(26):11942-7.
2010: Marieke A D van Zoelen; Ahmed Achouiti; Ann-Marie Schmidt; Huan Yang; Sandrine Florquin; Kevin Tracey; Tom van der Poll
Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis.
Critical care medicine 2010;38(6):1414-22.
2010: Christopher Czura; Arthur Schultz; Martin Kaipel; Anna Khadem; Jared M Huston; Valentin A Pavlov; Heinz Redl; Kevin Tracey
Vagus nerve stimulation regulates hemostasis in swine.
Shock (Augusta, Ga.) 2010;33(6):608-13.
2010: Haichao Wang; Wei Li; Shu Zhu; Jianhua Li; Jason D'Amore; Mary F Ward; Huan Yang; Rongqian Wu; Willi Jahnen-Dechent; Kevin Tracey; Ping Wang; Andrew E Sama
Peripheral administration of fetuin-A attenuates early cerebral ischemic injury in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(3):493-504.
2010: J Brian de Souza; Uduak Okomo; Neal D Alexander; Naveed Aziz; Benjamin Owens; Harparkash Kaur; Momodou Jasseh; Sant Muangnoicharoen; Percy F Sumariwalla; david charles warhurst; Stephen A Ward; David J Conway; Luis Ulloa; Kevin Tracey; Brian M J Foxwell; Paul M Kaye; Michael Walther
Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate.
PloS one 2010;5(4):e9867.
2010: Huan Yang; Kevin Tracey
Targeting HMGB1 in inflammation.
Biochimica et biophysica acta 2010;1799(1-2):149-56.
2009: Michael Miksa; Rongqian Wu; Weifeng Dong; Hidefumi Komura; Dhruv Amin; Youxin Ji; Zhimin Wang; Haichao Wang; Thanjavur S Ravikumar; Kevin Tracey; Ping Wang
Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor-factor VIII [corrected].
Journal of immunology (Baltimore, Md. : 1950) 2009;183(9):5983-90.
2009: Mauricio Rosas-Ballina; Kevin Tracey
The neurology of the immune system: neural reflexes regulate immunity.
Neuron 2009;64(1):28-32.
2009: Marieke A D van Zoelen; Koenraad F van der Sluijs; Ahmed Achouiti; Sandrine Florquin; Jennie M Braun-Pater; Huan Yang; Peter P Nawroth; Kevin Tracey; Angelika Bierhaus; Tom van der Poll
Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia.
Virology 2009;391(2):265-73.
2009: Stacey L Oke; Kevin Tracey
The inflammatory reflex and the role of complementary and alternative medical therapies.
Annals of the New York Academy of Sciences 2009;1172():172-80.
2009: Shu Zhu; Mala Ashok; Jianhua Li; Wei Li; Huan Yang; Ping Wang; Kevin Tracey; Andrew E Sama; Haichao Wang
Spermine protects mice against lethal sepsis partly by attenuating surrogate inflammatory markers.
Molecular medicine (Cambridge, Mass.) 2009;15(7-8):275-82.
2009: Mauricio Rosas-Ballina; Richard S Goldstein; Margot Gallowitsch-Puerta; Lihong Yang; Sergio Iván Valdés-Ferrer; Nirav B Patel; Sangeeta Chavan; Yousef Al-Abed; Huan Yang; Kevin Tracey
The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE.
Molecular medicine (Cambridge, Mass.) 2009;15(7-8):195-202.
2009: Jared M Huston; Mauricio Rosas-Ballina; Xiangying Xue; Oonagh Dowling; Kanta Ochani; Mahendar Ochani; Michael M Yeboah; Prodyot Chatterjee; Kevin Tracey; Christine N Metz
Cholinergic neural signals to the spleen down-regulate leukocyte trafficking via CD11b.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):552-9.
2009: Mauricio Rosas-Ballina; Kevin Tracey
Cholinergic control of inflammation.
Journal of internal medicine 2009;265(6):663-79.
2009: Franak M Batliwalla; Kevin Tracey
Introduction: The first Merinoff Symposium, 'Systemic Lupus: Bringing Science to the Patient'.
Journal of internal medicine 2009;265(6):622-4.
2009: Kevin Tracey
Reflex control of immunity.
Nature reviews. Immunology 2009;9(6):418-28.
2009: Marieke A D van Zoelen; Huan Yang; Sandrine Florquin; Joost C M Meijers; Shizuo Akira; Bernd Arnold; Peter P Nawroth; Angelika Bierhaus; Kevin Tracey; Tom van der Poll
Role of toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo.
Shock (Augusta, Ga.) 2009;31(3):280-4.
2009: Valentin A Pavlov; William R Parrish; Mauricio Rosas-Ballina; Mahendar Ochani; Margot Puerta; Kanta Ochani; Sangeeta Chavan; Yousef Al-Abed; Kevin Tracey
Brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway.
Brain, behavior, and immunity 2009;23(1):41-5.
2008: Sajjad Muhammad; Waleed Barakat; Stoyan Stoyanov; Sasidhar Murikinati; Huan Yang; Kevin Tracey; Martin Bendszus; Grazisa Rossetti; Peter P Nawroth; Angelika Bierhaus; Markus Schwaninger
The HMGB1 receptor RAGE mediates ischemic brain damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(46):12023-31.
2008: William R Parrish; Margot Gallowitsch-Puerta; Christopher Czura; Kevin Tracey
Experimental therapeutic strategies for severe sepsis: mediators and mechanisms.
Annals of the New York Academy of Sciences 2008;1144():210-36.
2008: jean-marc waldburger; David L Boyle; Valentin A Pavlov; Kevin Tracey; Gary S Firestein
Acetylcholine regulation of synoviocyte cytokine expression by the alpha7 nicotinic receptor.
Arthritis and rheumatism 2008;58(11):3439-49.
2008: jean-marc waldburger; David L Boyle; Meghan Edgar; Linda S Sorkin; Yaakov A Levine; Valentin A Pavlov; Kevin Tracey; Gary S Firestein
Spinal p38 MAP kinase regulates peripheral cholinergic outflow.
Arthritis and rheumatism 2008;58(9):2919-21.
2008: Jared Huston; Haichao Wang; Mahendar Ochani; Kanta Ochani; Mauricio Rosas-Ballina; Margot Gallowitsch-Puerta; Mala Ashok; Lihong Yang; Kevin Tracey; Huan Yang
Splenectomy protects against sepsis lethality and reduces serum HMGB1 levels.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(5):3535-9.
2008: William R Parrish; Mauricio Rosas-Ballina; Margot Gallowitsch-Puerta; Mahendar Ochani; Kanta Ochani; Li-Hong Yang; LaQueta Hudson; Xinchun Lin; Nirav Patel; Sarah M Johnson; Sangeeta Chavan; Richard S Goldstein; Christopher Czura; Edmund Miller; Yousef Al-Abed; Kevin Tracey; Valentin A Pavlov
Modulation of TNF release by choline requires alpha7 subunit nicotinic acetylcholine receptor-mediated signaling.
Molecular medicine (Cambridge, Mass.) 2008;14(9-10):567-74.
2008: Mauricio Rosas-Ballina; Mahendar Ochani; William R Parrish; Kanta Ochani; Yael T Harris; Jared Huston; Sangeeta Chavan; Kevin Tracey
Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):11008-13.
2008: M M Yeboah; X Xue; B Duan; M Ochani; Kevin Tracey; M Susin; C N Metz
Cholinergic agonists attenuate renal ischemia-reperfusion injury in rats.
Kidney international 2008;74(1):62-9.
2008: Annette Bruchfeld; Abdul Rashid Qureshi; Bengt Lindholm; Peter Barany; Lihong Yang; Peter Stenvinkel; Kevin Tracey
High Mobility Group Box Protein-1 correlates with renal function in chronic kidney disease (CKD).
Molecular medicine (Cambridge, Mass.) 2008;14(3-4):109-15.
2008: Stacey L Oke; Kevin Tracey
From CNI-1493 to the immunological homunculus: physiology of the inflammatory reflex.
Journal of leukocyte biology 2008;83(3):512-7.
2008: Jieping Yang; Rita Shah; Alexander G Robling; Evan Templeton; Huan Yang; Kevin Tracey; Joseph P Bidwell
HMGB1 is a bone-active cytokine.
Journal of cellular physiology 2008;214(3):730-9.
2007: Jared Huston; Margot Gallowitsch-Puerta; Mahendar Ochani; Kanta Ochani; Renqi Yuan; Mauricio Rosas-Ballina; Mala Ashok; Richard S Goldstein; Sangeeta Chavan; Valentin A Pavlov; Christine N Metz; Huan Yang; Christopher Czura; Haichao Wang; Kevin Tracey
Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis.
Critical care medicine 2007;35(12):2762-8.
2007: Deepak A Rao; Kevin Tracey; Jordan S Pober
IL-1alpha and IL-1beta are endogenous mediators linking cell injury to the adaptive alloimmune response.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):6536-46.
2007: Ryan M Levy; Kevin P Mollen; Jose M Prince; David J Kaczorowski; Raghuveer Vallabhaneni; Shiguang Liu; Kevin Tracey; Michael T Lotze; David J Hackam; Mitchell Fink; Yoram Vodovotz; Timothy R Billiar
Systemic inflammation and remote organ injury following trauma require HMGB1.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(4):R1538-44.
2007: Richard P Sloan; Peter A Shapiro; Ronald E Demeersman; Paula S McKinley; Kevin Tracey; Iordan Slavov; Yixin Fang; Pamela D Flood
Aerobic exercise attenuates inducible TNF production in humans.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;103(3):1007-11.
2007: Jie Fan; Yuehua Li; Ryan M Levy; Janet J Fan; David J Hackam; Yoram Vodovotz; Huan Yang; Kevin Tracey; Timothy R Billiar; Mark A Wilson
Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6573-80.
2007: Derek C Angus; Lihong Yang; Lan Kong; John A Kellum; Russell L Delude; Kevin Tracey; Lisa A Weissfeld
Circulating high-mobility group box 1 (HMGB1) concentrations are elevated in both uncomplicated pneumonia and pneumonia with severe sepsis.
Critical care medicine 2007;35(4):1061-7.
2007: Valentin A Pavlov; Mahendar Ochani; Li-Hong Yang; Margot Gallowitsch-Puerta; Kanta Ochani; Xinchun Lin; Jelena Levi; William R Parrish; Mauricio Rosas-Ballina; Christopher Czura; Greg La Rosa; Edmund Miller; Kevin Tracey; Yousef Al-Abed
Selective alpha7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis.
Critical care medicine 2007;35(4):1139-44.
2007: Wei Li; Jianhua Li; Mala Ashok; Rongqian Wu; Dazhi Chen; Lihong Yang; Huan Yang; Kevin Tracey; Ping Wang; Andrew E Sama; Haichao Wang
A cardiovascular drug rescues mice from lethal sepsis by selectively attenuating a late-acting proinflammatory mediator, high mobility group box 1.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3856-64.
2007: Richard S Goldstein; Annette Bruchfeld; Lihong Yang; Abdul Rashid Qureshi; Margot Gallowitsch-Puerta; Nirav B Patel; Brett J Huston; Sangeeta Chavan; Mauricio Rosas-Ballina; Peter K Gregersen; Christopher Czura; Richard P Sloan; Andrew E Sama; Kevin Tracey
Cholinergic anti-inflammatory pathway activity and High Mobility Group Box-1 (HMGB1) serum levels in patients with rheumatoid arthritis.
Molecular medicine (Cambridge, Mass.) 2007;13(3-4):210-5.
2007: Richard P Sloan; Heather McCreath; Kevin Tracey; Stephen Sidney; Kiang Liu; Teresa Seeman
RR interval variability is inversely related to inflammatory markers: the CARDIA study.
Molecular medicine (Cambridge, Mass.) 2007;13(3-4):178-84.
2007: Kevin Tracey
Physiology and immunology of the cholinergic antiinflammatory pathway.
The Journal of clinical investigation 2007;117(2):289-96.
2007: Haichao Wang; Wei Li; Richard Goldstein; Kevin Tracey; Andrew E Sama
HMGB1 as a potential therapeutic target.
Novartis Foundation symposium 2007;280():73-85; discussion 85-91, 160-4.
2007: Yasushi Sakata; Jian-Wen Dong; Jesus G Vallejo; Chien-Hua Huang; J Scott Baker; Kevin Tracey; Osamu Tacheuchi; Shizuo Akira; Douglas L Mann
Toll-like receptor 2 modulates left ventricular function following ischemia-reperfusion injury.
American journal of physiology. Heart and circulatory physiology 2007;292(1):H503-9.
2007: De Yang; Qian Chen; Huan Yang; Kevin Tracey; Michael Bustin; Joost J Oppenheim
High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin.
Journal of leukocyte biology 2007;81(1):59-66.
2006: Petar Popovic; Richard A DeMarco; Michael T Lotze; Steven E Winikoff; David L Bartlett; Arthur M Krieg; Z Sheng Guo; Charles K Brown; Kevin Tracey; Herbert J Zeh
High mobility group B1 protein suppresses the human plasmacytoid dendritic cell response to TLR9 agonists.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(12):8701-7.
2006: Valentin A Pavlov; Kevin Tracey
Controlling inflammation: the cholinergic anti-inflammatory pathway.
Biochemical Society transactions 2006;34(Pt 6):1037-40.
2006: Gloria Telusma; Sandip Datta; Ivan Mihajlov; Wenxue Ma; Jianhua Li; Huan Yang; Walter Newman; Bradley T Messmer; Boris Minev; Ingo G H Schmidt-Wolf; Kevin Tracey; Nicholas Chiorazzi; Davorka Messmer
Dendritic cell activating peptides induce distinct cytokine profiles.
International immunology 2006;18(11):1563-73.
2006: Man Yu; Haichao Wang; Aihao Ding; Douglas T Golenbock; Eicke Latz; Christopher Czura; Matthew J Fenton; Kevin Tracey; Huan Yang
HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.
Shock (Augusta, Ga.) 2006;26(2):174-9.
2006: Shixin Qin; Haichao Wang; Renqi Yuan; Hui Li; Mahendar Ochani; Kanta Ochani; Mauricio Rosas-Ballina; Christopher Czura; Jared Huston; Ed Miller; Xinchun Lin; Barbara Sherry; Anjali Kumar; Greg La Rosa; Walter Newman; Kevin Tracey; Huan Yang
Role of HMGB1 in apoptosis-mediated sepsis lethality.
The Journal of experimental medicine 2006;203(7):1637-42.
2006: Jared Huston; Mahendar Ochani; Mauricio Rosas-Ballina; Hong Liao; Kanta Ochani; Valentin A Pavlov; Margot Gallowitsch-Puerta; Mala Ashok; Christopher Czura; Brian Foxwell; Kevin Tracey; Luis Ulloa
Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis.
The Journal of experimental medicine 2006;203(7):1623-8.
2006: Kunihiko Izuishi; Allan Tsung; Geetha Jeyabalan; Nathan D Critchlow; Jianhua Li; Kevin Tracey; Richard A DeMarco; Michael T Lotze; Mitchell Fink; David A Geller; Timothy R Billiar
Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7154-8.
2006: Richard S Goldstein; Margot Gallowitsch-Puerta; Lihong Yang; Mauricio Rosas-Ballina; Jared Huston; Christopher Czura; David C Lee; Mary F Ward; Annette N Bruchfeld; Haichao Wang; Martin L Lesser; Adam L Church; Adam H Litroff; Andrew E Sama; Kevin Tracey
Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia.
Shock (Augusta, Ga.) 2006;25(6):571-4.
2006: David J van Westerloo; Ida A J Giebelen; Sandrine Florquin; Marco J Bruno; Greg La Rosa; Luis Ulloa; Kevin Tracey; Tom van der Poll
The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice.
Gastroenterology 2006;130(6):1822-30.
2006: Runkuan Yang; Tomoyuki Harada; Kevin P Mollen; Jose M Prince; Ryan M Levy; Joshua A Englert; Margot Gallowitsch-Puerta; LiHong Yang; Huan Yang; Kevin Tracey; Brian G Harbrecht; Timothy R Billiar; Mitchell Fink
Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock.
Molecular medicine (Cambridge, Mass.) 2006;12(4-6):105-14.
2006: Piotr Nowak; Babilonia Barqasho; Carl Johan Treutiger; Helena Erlandsson Harris; Kevin Tracey; Jan Andersson; Anders Sönnerborg
HMGB1 activates replication of latent HIV-1 in a monocytic cell-line, but inhibits HIV-1 replication in primary macrophages.
Cytokine 2006;34(1-2):17-23.
2006: Valentin A Pavlov; Mahendar Ochani; Margot Gallowitsch-Puerta; Kanta Ochani; Jared Huston; Christopher Czura; Yousef Al-Abed; Kevin Tracey
Central muscarinic cholinergic regulation of the systemic inflammatory response during endotoxemia.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(13):5219-23.
2006: Haichao Wang; Wei Li; Jianhua Li; Beatriz Rendon-Mitchell; Mahendar Ochani; Mala Ashok; Lihong Yang; Huan Yang; Kevin Tracey; Ping Wang; Andrew E Sama
The aqueous extract of a popular herbal nutrient supplement, Angelica sinensis, protects mice against lethal endotoxemia and sepsis.
The Journal of nutrition 2006;136(2):360-5.
2006: George Bowman; Robert H Bonneau; Vernon M Chinchilli; Kevin Tracey; Kevin M Cockroft
A novel inhibitor of inflammatory cytokine production (CNI-1493) reduces rodent post-hemorrhagic vasospasm.
Neurocritical care 2006;5(3):222-9.
2005: Margot Gallowitsch-Puerta; Kevin Tracey
Immunologic role of the cholinergic anti-inflammatory pathway and the nicotinic acetylcholine alpha 7 receptor.
Annals of the New York Academy of Sciences 2005;1062():209-19.
2005: Huan Yang; Kevin Tracey
High mobility group box 1 (HMGB1).
Critical care medicine 2005;33(12 Suppl):S472-4.
2005: Yousef Al-Abed; Darrin R Dabideen; Bayan Aljabari; Aline Valster; Davorka Messmer; Mahendar Ochani; Mahira Tanovic; Kanta Ochani; Michael Bacher; Ferdinando Nicoletti; Christine Metz; Valentin A Pavlov; Edmund Miller; Kevin Tracey
ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis.
The Journal of biological chemistry 2005;280(44):36541-4.
2005: Valentin A Pavlov; Kevin Tracey
The cholinergic anti-inflammatory pathway.
Brain, behavior, and immunity 2005;19(6):493-9.
2005: Kevin Tracey
Fat meets the cholinergic antiinflammatory pathway.
The Journal of experimental medicine 2005;202(8):1017-21.
2005: Weiwen Jiang; Jianhua Li; Margot Gallowitsch-Puerta; Kevin Tracey; David S Pisetsky
The effects of CpG DNA on HMGB1 release by murine macrophage cell lines.
Journal of leukocyte biology 2005;78(4):930-6.
2005: Ruben Zamora; Anatoly Grishin; Catarina Wong; Patricia Boyle; Jin Wang; David Hackam; Jeffrey Upperman; Kevin Tracey; Henri R Ford
High-mobility group box 1 protein is an inflammatory mediator in necrotizing enterocolitis: protective effect of the macrophage deactivator semapimod.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(4):G643-52.
2005: Xinchun Lin; Huan Yang; Tohru Sakuragi; Maowen Hu; Lin L Mantell; Shinichiro Hayashi; Yousef Al-Abed; Kevin Tracey; Luis Ulloa; Edmund Miller
Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis.
American journal of physiology. Lung cellular and molecular physiology 2005;289(4):L583-90.
2005: Jessica Jones-Carson; Giamila Fantuzzi; Britta Siegmund; Charles Dinarello; Kevin Tracey; Haichao Wang; Ferric C Fang; Andrés Vazquez-Torres
Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock.
The Journal of infectious diseases 2005;192(6):1039-46.
2005: Christine N Metz; Kevin Tracey
It takes nerve to dampen inflammation.
Nature immunology 2005;6(8):756-7.
2005: Huan Yang; Haichao Wang; Christopher Czura; Kevin Tracey
The cytokine activity of HMGB1.
Journal of leukocyte biology 2005;78(1):1-8.
2005: David J van Westerloo; Ida A J Giebelen; Sandrine Florquin; Joost Daalhuisen; Marco J Bruno; Alex F de Vos; Kevin Tracey; Tom van der Poll
The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis.
The Journal of infectious diseases 2005;191(12):2138-48.
2005: Rubina W Saeed; Santosh Varma; Tina Peng-Nemeroff; Barbara Sherry; David Balakhaneh; Jared Huston; Kevin Tracey; Yousef Al-Abed; Christine N Metz
Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation.
The Journal of experimental medicine 2005;201(7):1113-23.
2005: Allan Tsung; Rohit Sahai; Hiroyuki Tanaka; Atsunori Nakao; Mitchell Fink; Michael T Lotze; Huan Yang; Jianhua Li; Kevin Tracey; David A Geller; Timothy R Billiar
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion.
The Journal of experimental medicine 2005;201(7):1135-43.
2005: Michael T Lotze; Kevin Tracey
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal.
Nature reviews. Immunology 2005;5(4):331-42.
2005: Guoqian Chen; Jianhua Li; Xiaoling Qiang; Christopher Czura; Mahendar Ochani; Kanta Ochani; Luis Ulloa; Huan Yang; Kevin Tracey; Ping Wang; Andrew E Sama; Haichao Wang
Suppression of HMGB1 release by stearoyl lysophosphatidylcholine:an additional mechanism for its therapeutic effects in experimental sepsis.
Journal of lipid research 2005;46(4):623-7.
2005: Jonas Sundén-Cullberg; Anna Norrby-Teglund; Ari Rouhiainen; Heikki Rauvala; Gunilla Herman; Kevin Tracey; Martin L Lee; Jan Andersson; Leif Tokics; Carl Johan Treutiger
Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock.
Critical care medicine 2005;33(3):564-73.
2005: Lisa M Alleva; H Yang; Kevin Tracey; Ian A Clark
High mobility group box 1 (HMGB1) protein: possible amplification signal in the pathogenesis of falciparum malaria.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2005;99(3):171-4.
2005: Xiaoxuan Cui; Rongqian Wu; Mian Zhou; Weifeng Dong; Luis Ulloa; Huan Yang; Haichao Wang; Kevin Tracey; H Hank Simms; Ping Wang
Adrenomedullin and its binding protein attenuate the proinflammatory response after hemorrhage.
Critical care medicine 2005;33(2):391-8.
2005: Luis Ulloa; Kevin Tracey
The "cytokine profile": a code for sepsis.
Trends in molecular medicine 2005;11(2):56-63.
2005: Christopher Czura; Kevin Tracey
Autonomic neural regulation of immunity.
Journal of internal medicine 2005;257(2):156-66.
2004: Gail E Mullins; J Sunden-Cullberg; A-S Johansson; Ari Rouhiainen; H Erlandsson-Harris; H Yang; Kevin Tracey; Heikki Rauvala; J Palmblad; Jan Andersson; Carl Johan Treutiger
Activation of human umbilical vein endothelial cells leads to relocation and release of high-mobility group box chromosomal protein 1.
Scandinavian journal of immunology 2004;60(6):566-73.
2004: Rubina W Saeed; Santosh Varma; Tina Peng; Kevin Tracey; Barbara Sherry; Christine N Metz
Ethanol blocks leukocyte recruitment and endothelial cell activation in vivo and in vitro.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6376-83.
2004: Hong Wang; Hong Liao; Mahendar Ochani; Marilou Justiniani; Xinchun Lin; Lihong Yang; Yousef Al-Abed; Haichao Wang; Christine Metz; Edmund Miller; Kevin Tracey; Luis Ulloa
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis.
Nature medicine 2004;10(11):1216-21.
2004: Guoqian Chen; Jianhua Li; Mahendar Ochani; Beatriz Rendon-Mitchell; Xiaoling Qiang; Srinivas M Susarla; Luis Ulloa; Huan Yang; Saijun Fan; Sanna Goyert; Ping Wang; Kevin Tracey; Andrew E Sama; Haichao Wang
Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms.
Journal of leukocyte biology 2004;76(5):994-1001.
2004: Valentin A Pavlov; Kevin Tracey
Neural regulators of innate immune responses and inflammation.
Cellular and molecular life sciences : CMLS 2004;61(18):2322-31.
2004: Ulf Andersson; Kevin Tracey
HMGB1 as a mediator of necrosis-induced inflammation and a therapeutic target in arthritis.
Rheumatic diseases clinics of North America 2004;30(3):627-37, xi.
2004: Davorka Messmer; Huan Yang; Gloria Telusma; Faye Knoll; Jianhua Li; Bradley T Messmer; Kevin Tracey; Nicholas Chiorazzi
High mobility group box protein 1: an endogenous signal for dendritic cell maturation and Th1 polarization.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(1):307-13.
2004: Jianhua Li; Haichao Wang; James M Mason; Jacob Levine; Man Yu; Luis Ulloa; Christopher Czura; Kevin Tracey; Huan Yang
Recombinant HMGB1 with cytokine-stimulating activity.
Journal of immunological methods 2004;289(1-2):211-23.
2004: Kevin Tracey; H Shaw Warren
Human genetics: an inflammatory issue.
Nature 2004;429(6987):35-7.
2004: Frédéric Catez; Huan Yang; Kevin Tracey; Raymond Reeves; Tom Misteli; Michael Bustin
Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin.
Molecular and cellular biology 2004;24(10):4321-8.
2004: H Wang; H Yang; Kevin Tracey
Extracellular role of HMGB1 in inflammation and sepsis.
Journal of internal medicine 2004;255(3):320-31.
2004: U G Andersson; Kevin Tracey
HMGB1, a pro-inflammatory cytokine of clinical interest: introduction.
Journal of internal medicine 2004;255(3):318-9.
2004: Haichao Wang; Christopher Czura; Kevin Tracey
Lipid unites disparate syndromes of sepsis.
Nature medicine 2004;10(2):124-5.
2004: Huan Yang; Mahendar Ochani; Jianhua Li; Xiaoling Qiang; Mahira Tanovic; Helena Erlandsson Harris; Srinivas M Susarla; Luis Ulloa; Hong Wang; Robert DiRaimo; Christopher Czura; Haichao Wang; Jesse Roth; H Shaw Warren; Mitchell Fink; Matthew J Fenton; Ulf Andersson; Kevin Tracey
Reversing established sepsis with antagonists of endogenous high-mobility group box 1.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):296-301.
2004: Guoqian Chen; Da-Zhi Chen; Jianhua Li; Christopher Czura; Kevin Tracey; Andrew E Sama; Haichao Wang
Pathogenic role of HMGB1 in SARS?
Medical hypotheses 2004;63(4):691-5.
2004: Christopher Czura; Huan Yang; Carol Ann Amella; Kevin Tracey
HMGB1 in the immunology of sepsis (not septic shock) and arthritis.
Advances in immunology 2004;84():181-200.
2003: Kevin A O'Connor; Michael K Hansen; C Rachal Pugh; Molly M Deak; Joseph C Biedenkapp; Erin D Milligan; John D Johnson; Haichao Wang; Steven F Maier; Kevin Tracey; Linda R Watkins
Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects.
Cytokine 2003;24(6):254-65.
2003: Carl Johan Treutiger; Gail E Mullins; A-S M Johansson; Ari Rouhiainen; Heikki Rauvala; H Erlandsson-Harris; Ulf Andersson; H Yang; Kevin Tracey; Jan Andersson; J E W Palmblad
High mobility group 1 B-box mediates activation of human endothelium.
Journal of internal medicine 2003;254(4):375-85.
2003: Mojgan H Naghavi; Piotr Nowak; Jan Andersson; Anders Sönnerborg; Huan Yang; Kevin Tracey; Anders Vahlne
Intracellular high mobility group B1 protein (HMGB1) represses HIV-1 LTR-directed transcription in a promoter- and cell-specific manner.
Virology 2003;314(1):179-89.
2003: Riikka Kokkola; Jianhua Li; Erik Sundberg; Ann-Charlotte Aveberger; Karin Palmblad; Huan Yang; Kevin Tracey; Ulf Andersson; Helena Erlandsson Harris
Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity.
Arthritis and rheumatism 2003;48(7):2052-8.
2003: Christopher Czura; Huan Yang; Kevin Tracey
High mobility group box-1 as a therapeutic target downstream of tumor necrosis factor.
The Journal of infectious diseases 2003;187 Suppl 2():S391-6.
2003: Valentin A Pavlov; Hong Wang; Christopher Czura; Steven G Friedman; Kevin Tracey
The cholinergic anti-inflammatory pathway: a missing link in neuroimmunomodulation.
Molecular medicine (Cambridge, Mass.) 2003;9(5-8):125-34.
2003: Steven G Friedman; Christopher Czura; Kevin Tracey
The gesture life of high mobility group box 1.
Current opinion in clinical nutrition and metabolic care 2003;6(3):283-7.
2003: Wei Li; Xi-Ming Yuan; Svetlana Ivanova; Kevin Tracey; John W Eaton; Ulf T Brunk
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin.
The Biochemical journal 2003;371(Pt 2):429-36.
2003: Luis Ulloa; Franak M Batliwalla; Ulf Andersson; Peter K Gregersen; Kevin Tracey
High mobility group box chromosomal protein 1 as a nuclear protein, cytokine, and potential therapeutic target in arthritis.
Arthritis and rheumatism 2003;48(4):876-81.
2003: Michael A Matthay; Guy A Zimmerman; Charles Esmon; Jahar Bhattacharya; Barry S Coller; Claire Doerschuk; Joanna Floros; Michael A Gimbrone; Eric Hoffman; Rolf D Hubmayr; Mark Leppert; Sadis Matalon; Robert Munford; Polly Parsons; Arthur Slutsky; Kevin Tracey; Peter Ward; Dorothy B Gail; Andrea L Harabin
Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group.
American journal of respiratory and critical care medicine 2003;167(7):1027-35.
2003: Beatriz Rendon-Mitchell; Mahendar Ochani; Jianhua Li; Jialian Han; Haichao Wang; Huan Yang; Srinivas M Susarla; Christopher Czura; Robert A Mitchell; Guoqian Chen; Andrew E Sama; Kevin Tracey; Haichao Wang
IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(7):3890-7.
2003: Jong Sung Park; John Arcaroli; Ho-Kee Yum; Huan Yang; Haichao Wang; Kuang-Yao Yang; Kang-Hyeon Choe; Derek Strassheim; Todd M Pitts; Kevin Tracey; Edward Abraham
Activation of gene expression in human neutrophils by high mobility group box 1 protein.
American journal of physiology. Cell physiology 2003;284(4):C870-9.
2003: Erin D Milligan; Carin M Twining; Marucia Chacur; Joseph C Biedenkapp; Kevin O'Connor; Stephen Poole; Kevin Tracey; David Martin; Steven F Maier; Linda R Watkins
Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(3):1026-40.
2003: Hong Wang; Man Yu; Mahendar Ochani; Carol Ann Amella; Mahira Tanovic; Srinivas M Susarla; Jian Hua Li; Haichao Wang; Huan Yang; Luis Ulloa; Yousef Al-Abed; Christopher Czura; Kevin Tracey
Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation.
Nature 2003;421(6921):384-8.
2003: Christopher Czura; Steven G Friedman; Kevin Tracey
Neural inhibition of inflammation: the cholinergic anti-inflammatory pathway.
Journal of endotoxin research 2003;9(6):409-13.
2003: Ulf Andersson; Kevin Tracey
HMGB1 in sepsis.
Scandinavian journal of infectious diseases 2003;35(9):577-84.
2003: Jianhua Li; Riikka Kokkola; Siamak Tabibzadeh; Runkuan Yang; Mahendar Ochani; Xiaoling Qiang; Helena Erlandsson Harris; Christopher Czura; Hong Wang; Luis Ulloa; Haichao Wang; H Shaw Warren; Lyle L Moldawer; Mitchell Fink; Ulf Andersson; Kevin Tracey; Huan Yang
Structural basis for the proinflammatory cytokine activity of high mobility group box 1.
Molecular medicine (Cambridge, Mass.) 2003;9(1-2):37-45.
2003: Christopher Czura; Kevin Tracey
Targeting high mobility group box 1 as a late-acting mediator of inflammation.
Critical care medicine 2003;31(1 Suppl):S46-50.
2002: Kevin Tracey
The inflammatory reflex.
Nature 2002;420(6917):853-9.
2002: Ulf Andersson; Helena Erlandsson Harris; Huan Yang; Kevin Tracey
HMGB1 as a DNA-binding cytokine.
Journal of leukocyte biology 2002;72(6):1084-91.
2002: Thomas R Bernik; Steven G Friedman; Mahendar Ochani; Robert DiRaimo; Srinivas M Susarla; Christopher Czura; Kevin Tracey
Cholinergic antiinflammatory pathway inhibition of tumor necrosis factor during ischemia reperfusion.
Journal of vascular surgery 2002;36(6):1231-6.
2002: Riikka Kokkola; Erik Sundberg; Ann-Kristin Ulfgren; Karin Palmblad; Jianhua Li; Hong Wang; Luis Ulloa; Huan Yang; Joy (Xiao-Jie) Yan; Richard Furie; Nicholas Chiorazzi; Kevin Tracey; Ulf Andersson; Helena Erlandsson Harris
High mobility group box chromosomal protein 1: a novel proinflammatory mediator in synovitis.
Arthritis and rheumatism 2002;46(10):2598-603.
2002: Luis Ulloa; Mahendar Ochani; Huan Yang; Mahira Tanovic; Daniel Halperin; Runkuan Yang; Christopher Czura; Mitchell Fink; Kevin Tracey
Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12351-6.
2002: Penny L Sappington; Runkuan Yang; Huan Yang; Kevin Tracey; Russell L Delude; Mitchell Fink
HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice.
Gastroenterology 2002;123(3):790-802.
2002: Robert S Munford; Kevin Tracey
Is severe sepsis a neuroendocrine disease?
Molecular medicine (Cambridge, Mass.) 2002;8(8):437-42.
2002: Huan Yang; Hong Wang; Thomas R Bernik; Svetlana Ivanova; Haichao Wang; Luis Ulloa; Jesse Roth; John W Eaton; Kevin Tracey
Globin attenuates the innate immune response to endotoxin.
Shock (Augusta, Ga.) 2002;17(6):485-90.
2002: Davide Agnello; Haichao Wang; Huan Yang; Kevin Tracey; Pietro Ghezzi
HMGB-1, a DNA-binding protein with cytokine activity, induces brain TNF and IL-6 production, and mediates anorexia and taste aversion.
Cytokine 2002;18(4):231-6.
2002: Kevin Tracey
Lethal weight loss: the focus shifts to signal transduction.
Science's STKE : signal transduction knowledge environment 2002;2002(130):pe21.
2002: Svetlana Ivanova; Franak M Batliwalla; JD Mocco; Szilard Kiss; Judy Huang; William J Mack; Alexander L Coon; John W Eaton; Yousef Al-Abed; Peter K Gregersen; Esther Shohami; E Sander Connolly; Kevin Tracey
Neuroprotection in cerebral ischemia by neutralization of 3-aminopropanal.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5579-84.
2002: Thomas R Bernik; Steven G Friedman; Mahendar Ochani; Robert DiRaimo; Luis Ulloa; Huan Yang; Samridhi Sudan; Christopher Czura; Svetlana M Ivanova; Kevin Tracey
Pharmacological stimulation of the cholinergic antiinflammatory pathway.
The Journal of experimental medicine 2002;195(6):781-8.
2002: Huan Yang; Haichao Wang; Christopher Czura; Kevin Tracey
HMGB1 as a cytokine and therapeutic target.
Journal of endotoxin research 2002;8(6):469-72.
2001: Erin D Milligan; Kevin A O'Connor; C B Armstrong; Michael K Hansen; David Martin; Kevin Tracey; Steven F Maier; Linda R Watkins
Systemic administration of CNI-1493, a p38 mitogen-activated protein kinase inhibitor, blocks intrathecal human immunodeficiency virus-1 gp120-induced enhanced pain states in rats.
The journal of pain : official journal of the American Pain Society 2001;2(6):326-33.
2001: Marucia Chacur; Erin D Milligan; Lawrence S Gazda; C Armstrong; H Wang; Kevin Tracey; Steven F Maier; Linda R Watkins
A new model of sciatic inflammatory neuritis (SIN): induction of unilateral and bilateral mechanical allodynia following acute unilateral peri-sciatic immune activation in rats.
Pain 2001;94(3):231-44.
2001: Hong Wang; Huan Yang; Christopher Czura; Andrew E Sama; Kevin Tracey
HMGB1 as a late mediator of lethal systemic inflammation.
American journal of respiratory and critical care medicine 2001;164(10 Pt 1):1768-73.
2001: Kevin Tracey; Christopher Czura; Svetlana Ivanova
Mind over immunity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(9):1575-6.
2001: Huan Yang; Hong Wang; Kevin Tracey
HMG-1 rediscovered as a cytokine.
Shock (Augusta, Ga.) 2001;15(4):247-53.
2001: Michael Ombrellino; Hong Wang; Huan Yang; M Zhang; JM Vishnubhakat; A Frazier; Larry A Scher; Steven G Friedman; Kevin Tracey
Fetuin, a negative acute phase protein, attenuates TNF synthesis and the innate inflammatory response to carrageenan.
Shock (Augusta, Ga.) 2001;15(3):181-5.
2001: Karin Palmblad; Helena Erlandsson Harris; Kevin Tracey; U Andersson
Dynamics of early synovial cytokine expression in rodent collagen-induced arthritis : a therapeutic study using a macrophage-deactivating compound.
The American journal of pathology 2001;158(2):491-500.
2001: Christopher Czura; Hong Wang; Kevin Tracey
Dual roles for HMGB1: DNA binding and cytokine.
Journal of endotoxin research 2001;7(4):315-21.
2000: LV Borovikova; Svetlana Ivanova; D Nardi; M Zhang; Huan Yang; Michael Ombrellino; Kevin Tracey
Role of vagus nerve signaling in CNI-1493-mediated suppression of acute inflammation.
Autonomic neuroscience : basic & clinical 2000;85(1-3):141-7.
2000: Edward Abraham; John Arcaroli; A Carmody; Haichao Wang; Kevin Tracey
HMG-1 as a mediator of acute lung inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):2950-4.
2000: Carl Granert; H Abdalla; Lars Lindquist; A Diab; M Bahkiet; Kevin Tracey; Jan Andersson
Suppression of macrophage activation with CNI-1493 increases survival in infant rats with systemic Haemophilus influenzae infection.
Infection and immunity 2000;68(9):5329-34.
2000: Ulf Andersson; Hong Wang; Karin Palmblad; Ann-Charlotte Aveberger; O Bloom; Helena Erlandsson Harris; A Janson; Riikka Kokkola; M Zhang; Huan Yang; Kevin Tracey
High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes.
The Journal of experimental medicine 2000;192(4):565-70.
2000: W Denham; Juhua Yang; H Wang; G Botchkina; Kevin Tracey; J Norman
Inhibition of p38 mitogen activate kinase attenuates the severity of pancreatitis-induced adult respiratory distress syndrome.
Critical care medicine 2000;28(7):2567-72.
2000: LV Borovikova; Svetlana Ivanova; M Zhang; Huan Yang; GI Botchkina; L R Watkins; Hong Wang; N Abumrad; John W Eaton; Kevin Tracey
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin.
Nature 2000;405(6785):458-62.
2000: Erin D Milligan; K K Mehmert; JL Hinde; LO Harvey; David Martin; Kevin Tracey; Steven F Maier; Linda R Watkins
Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120.
Brain research 2000;861(1):105-16.
2000: M Zhang; Hong Wang; Kevin Tracey
Regulation of macrophage activation and inflammation by spermine: a new chapter in an old story.
Critical care medicine 2000;28(4 Suppl):N60-6.
1999: Michael Ombrellino; Hong Wang; M S Ajemian; A Talhouk; Larry A Scher; Steven G Friedman; Kevin Tracey
Increased serum concentrations of high-mobility-group protein 1 in haemorrhagic shock.
Lancet 1999;354(9188):1446-7.
1999: Martin J D'Souza; Carl W Oettinger; GV Milton; Kevin Tracey
Prevention of lethality and suppression of proinflammatory cytokines in experimental septic shock by microencapsulated CNI-1493.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999;19(10):1125-33.
1999: M Zhang; LV Borovikova; Hong Wang; Christine Metz; Kevin Tracey
Spermine inhibition of monocyte activation and inflammation.
Molecular medicine (Cambridge, Mass.) 1999;5(9):595-605.
1999: Hong Wang; JM Vishnubhakat; O Bloom; M Zhang; Michael Ombrellino; Andrew E Sama; Kevin Tracey
Proinflammatory cytokines (tumor necrosis factor and interleukin 1) stimulate release of high mobility group protein-1 by pituicytes.
Surgery 1999;126(2):389-92.
1999: Juhua Yang; C Murphy; W Denham; G Botchkina; Kevin Tracey; J Norman
Evidence of a central role for p38 map kinase induction of tumor necrosis factor alpha in pancreatitis-associated pulmonary injury.
Surgery 1999;126(2):216-22.
1999: Hong Wang; O Bloom; M Zhang; JM Vishnubhakat; Michael Ombrellino; Jiantu Che; A Frazier; Huan Yang; Svetlana Ivanova; LV Borovikova; K R Manogue; E Faist; Edward Abraham; J Andersson; U Andersson; Patricia E Molina; Naji N Abumrad; Andrew E Sama; Kevin Tracey
HMG-1 as a late mediator of endotoxin lethality in mice.
Science (New York, N.Y.) 1999;285(5425):248-51.
1999: GI Botchkina; E Geimonen; M L Bilof; O Villarreal; Kevin Tracey
Loss of NF-kappaB activity during cerebral ischemia and TNF cytotoxicity.
Molecular medicine (Cambridge, Mass.) 1999;5(6):372-81.
1999: Carol K Petito; Rebecca Adkins; Kevin Tracey; B Roberts; Jorge Torres-Munoz; Micheline McCarthy; C Czeisler
Chronic systemic administration of tumor necrosis factor alpha and HIV gp120: effects on adult rodent brain and blood-brain barrier.
Journal of neurovirology 1999;5(3):314-8.
1999: C Mendez; AA Kramer; KF Salhab; G A Valdes; James G Norman; Kevin Tracey; Larry C Carey
Tolerance to shock: an exploration of mechanism.
Annals of surgery 1999;229(6):843-9; discussion 849-50.
1999: Abigail E Hunt; Ferdinand V Lali; JD Lord; Brad H Nelson; T Miyazaki; Kevin Tracey; Brian M J Foxwell
Role of interleukin (IL)-2 receptor beta-chain subdomains and Shc in p38 mitogen-activated protein (MAP) kinase and p54 MAP kinase (stress-activated protein Kinase/c-Jun N-terminal kinase) activation. IL-2-driven proliferation is independent of p38 and p54 MAP kinase activation.
The Journal of biological chemistry 1999;274(11):7591-7.
1999: Kevin Tracey; Edward Abraham
From mouse to man: or what have we learned about cytokine-based anti-inflammatory therapies?
Shock (Augusta, Ga.) 1999;11(3):224-5.
1999: K kerlund; H Erlandsson Harris; Kevin Tracey; H Wang; T Fehniger; L Klareskog; J Andersson; U Andersson
Anti-inflammatory effects of a new tumour necrosis factor-alpha (TNF-alpha) inhibitor (CNI-1493) in collagen-induced arthritis (CIA) in rats.
Clinical and experimental immunology 1999;115(1):32-41.
1998: O Bloom; Hong Wang; Svetlana Ivanova; JM Vishnubhakat; Michael Ombrellino; Kevin Tracey
Hypophysectomy, high tumor necrosis factor levels, and hemoglobinemia in lethal endotoxemic shock.
Shock (Augusta, Ga.) 1998;10(6):395-400.
1998: Hong Wang; M Zhang; M Bianchi; B Sherry; A Sama; Kevin Tracey
Fetuin (alpha2-HS-glycoprotein) opsonizes cationic macrophagedeactivating molecules.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14429-34.
1998: Patricia E Molina; L Qian; D Schuhlein; RJ Naukam; Hong Wang; Kevin Tracey; Naji N Abumrad
CNI-1493 attenuates hemodynamic and pro-inflammatory responses to LPS.
Shock (Augusta, Ga.) 1998;10(5):329-34.
1998: Juhua Yang; W Denham; Gay Carter; Kevin Tracey; J Norman
Macrophage pacification reduces rodent pancreatitis-induced hepatocellular injury through down-regulation of hepatic tumor necrosis factor alpha and interleukin-1beta.
Hepatology (Baltimore, Md.) 1998;28(5):1282-8.
1998: Juhua Yang; W Denham; Kevin Tracey; H Wang; AA Kramer; KF Salhab; J Norman
The physiologic consequences of macrophage pacification during severe acute pancreatitis.
Shock (Augusta, Ga.) 1998;10(3):169-75.
1998: Svetlana Ivanova; GI Botchkina; Yousef Al-Abed; ME Meistrell; Franak M Batliwalla; J M Dubinsky; costantino iadecola; Hong Wang; Peter K Gregersen; John W Eaton; Kevin Tracey
Cerebral ischemia enhances polyamine oxidation: identification of enzymatically formed 3-aminopropanal as an endogenous mediator of neuronal and glial cell death.
The Journal of experimental medicine 1998;188(2):327-40.
1998: X Yang; Matthias Szabolcs; OP Minanov; Ningsheng Ma; Robert R Sciacca; M Bianchi; Kevin Tracey; Robert Michler; Paul J Cannon
CNI-1493 prolongs survival and reduces myocyte loss, apoptosis, and inflammation during rat cardiac allograft rejection.
Journal of cardiovascular pharmacology 1998;32(1):146-55.
1998: JA Martiney; AJ Rajan; Peter Charles; Anthony Cerami; PC Ulrich; S Macphail; Kevin Tracey; Celia F Brosnan
Prevention and treatment of experimental autoimmune encephalomyelitis by CNI-1493, a macrophage-deactivating agent.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5588-95.
1998: M M Kemeny; Galina I Botchkina; Mahendar Ochani; M Bianchi; C Urmacher; Kevin Tracey
The tetravalent guanylhydrazone CNI-1493 blocks the toxic effects of interleukin-2 without diminishing antitumor efficacy.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4561-6.
1998: Sung Ho Hyon; Kevin Tracey; Dixon B Kaufman
Specific inhibition of macrophage-derived proinflammatory cytokine synthesis with a tetravalent guanylhydrazone CNI-1493 accelerates early islet graft function posttransplant.
Transplantation proceedings 1998;30(2):409-10.
1998: Kevin Tracey
Suppression of TNF and other proinflammatory cytokines by the tetravalent guanylhydrazone CNI-1493.
Progress in clinical and biological research 1998;397():335-43.
1997: F Amiot; C Fitting; Kevin Tracey; J M Cavaillon; François Dautry
Lipopolysaccharide-induced cytokine cascade and lethality in LT alpha/TNF alpha-deficient mice.
Molecular medicine (Cambridge, Mass.) 1997;3(12):864-75.
1997: W Denham; G Fink; Juhua Yang; P Ulrich; Kevin Tracey; J Norman
Small molecule inhibition of tumor necrosis factor gene processing during acute pancreatitis prevents cytokine cascade progression and attenuates pancreatitis severity.
The American surgeon 1997;63(12):1045-9; discussion 1049-50.
1997: Galina I Botchkina; ME Meistrell; Inna L Botchkina; Kevin Tracey
Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia.
Molecular medicine (Cambridge, Mass.) 1997;3(11):765-81.
1997: ME Meistrell; Galina I Botchkina; Hong Wang; E Di Santo; K M Cockroft; O Bloom; JM Vishnubhakat; Pietro Ghezzi; Kevin Tracey
Tumor necrosis factor is a brain damaging cytokine in cerebral ischemia.
Shock (Augusta, Ga.) 1997;8(5):341-8.
1997: Lars Björk; Kevin Tracey; PC Ulrich; M Bianchi; PS Cohen; K Akerlund; T E Fehniger; U Andersson; Jan Andersson
Targeted suppression of cytokine production in monocytes but not in T lymphocytes by a tetravalent guanylhydrazone (CNI-1493).
The Journal of infectious diseases 1997;176(5):1303-12.
1997: J A Boockvar; K Black; S Malik; A Stanek; Kevin Tracey
Subacute paraparesis induced by venous thrombosis of a spinal angiolipoma: a case report.
Spine 1997;22(19):2304-8.
1997: H Wang; M Zhang; K Soda; Andrew E Sama; Kevin Tracey
Fetuin protects the fetus from TNF.
Lancet 1997;350(9081):861-2.
1997: Linda R Watkins; David Martin; P Ulrich; Kevin Tracey; Steven F Maier
Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat.
Pain 1997;71(3):225-35.
1997: M Zhang; T Caragine; Hong Wang; PS Cohen; GI Botchkina; K Soda; M Bianchi; PC Ulrich; Anthony Cerami; Barbara Sherry; Kevin Tracey
Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: a counterregulatory mechanism that restrains the immune response.
The Journal of experimental medicine 1997;185(10):1759-68.
1997: PS Cohen; Helena Schmidtmayerova; J Dennis; Larisa Dubrovsky; Barbara Sherry; Hong Wang; Michael Bukrinsky; Kevin Tracey
The critical role of p38 MAP kinase in T cell HIV-1 replication.
Molecular medicine (Cambridge, Mass.) 1997;3(5):339-46.
1996: K M Cockroft; M Meistrell; G A Zimmerman; D Risucci; O Bloom; A Cerami; Kevin Tracey
Cerebroprotective effects of aminoguanidine in a rodent model of stroke.
Stroke; a journal of cerebral circulation 1996;27(8):1393-8.
1996: P S Cohen; Harikrishna Nakshatri; J Dennis; T Caragine; M Bianchi; Anthony Cerami; Kevin Tracey
CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):3967-71.
1996: Kevin Tracey
Repairing the broken heart of dilated cardiomyopathy.
Lancet 1996;347(9009):1129-30.
1996: M Bianchi; O Bloom; T Raabe; P S Cohen; Jason Chesney; Barbara Sherry; Helena Schmidtmayerova; T Calandra; X Zhang; Michael Bukrinsky; PC Ulrich; Anthony Cerami; Kevin Tracey
Suppression of proinflammatory cytokines in monocytes by a tetravalent guanylhydrazone.
The Journal of experimental medicine 1996;183(3):927-36.
1996: Carla Cerami Hand; X Zhang; P Ulrich; M Bianchi; Kevin Tracey; BJ Berger
High-performance liquid chromatographic method for guanylhydrazone compounds.
Journal of chromatography. B, Biomedical applications 1996;675(1):71-5.
1995: Kevin Tracey
TNF and Mae West or: death from too much of a good thing.
Lancet 1995;345(8942):75-6.
1995: B A Sherry; G Alava; Kevin Tracey; J Martiney; Anthony Cerami; A F Slater
Malaria-specific metabolite hemozoin mediates the release of several potent endogenous pyrogens (TNF, MIP-1 alpha, and MIP-1 beta) in vitro, and altered thermoregulation in vivo.
Journal of inflammation 1995;45(2):85-96.
1994: Kevin Tracey; Anthony Cerami
Tumor necrosis factor: a pleiotropic cytokine and therapeutic target.
Annual review of medicine 1994;45():491-503.
1993: Jürgen Bernhagen; T Calandra; R A Mitchell; S B Martin; Kevin Tracey; Wolfgang Voelter; K R Manogue; Anthony Cerami; Richard Bucala
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia.
Nature 1993;365(6448):756-9.
1993: Kevin Tracey; A Cerami
Tumor necrosis factor: an updated review of its biology.
Critical care medicine 1993;21(10 Suppl):S415-22.
1993: E Vlachopapadopoulou; Kevin Tracey; M Capella; C Gilker; D E Matthews
Increased energy expenditure in a patient with diencephalic syndrome.
The Journal of pediatrics 1993;122(6):922-4.
1993: Kevin Tracey; Anthony Cerami
Tumor necrosis factor, other cytokines and disease.
Annual review of cell biology 1993;9():317-43.
1992: Kevin Tracey; A Cerami
Tumor necrosis factor in the malnutrition (cachexia) of infection and cancer.
The American journal of tropical medicine and hygiene 1992;47(1 Pt 2):2-7.
1992: Kevin Tracey; A Cerami
Tumor necrosis factor and regulation of metabolism in infection: role of systemic versus tissue levels.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1992;200(2):233-9.
1992: T J Fahey; Kevin Tracey; P Tekamp-Olson; L S Cousens; W G Jones; G T Shires; Anthony Cerami; Barbara Sherry
Macrophage inflammatory protein 1 modulates macrophage function.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(9):2764-9.
1992: Kevin Tracey
TNF and other cytokines in the metabolism of septic shock and cachexia.
Clinical nutrition (Edinburgh, Scotland) 1992;11(1):1-11.
1992: Kevin Tracey; A Cerami
Pleiotropic effects of TNF in infection and neoplasia: beneficial, inflammatory, catabolic, or injurious.
Immunology series 1992;56():431-52.
1992: H Jen; Kevin Tracey; Z Catz; A McEwan
Bone scan appearance of diastasis pubis in association with congenital extrophy of the bladder.
Clinical nuclear medicine 1992;17(1):47.
1992: Kevin Tracey; A Cerami
Tumor necrosis factor in metabolism of disease: hormonal actions versus local tissue effects.
Nouvelle revue française d'hématologie 1992;34 Suppl():S37-42.
1991: Yuman Fong; J D Albert; Kevin Tracey; D G Hesse; S Calvano; D E Matthews; Stephen F Lowry
The influence of substrate background on the acute metabolic response to epinephrine and cortisol.
The Journal of trauma 1991;31(11):1467-76.
1991: Kevin Tracey
Tumor necrosis factor (cachectin) in the biology of septic shock syndrome.
Circulatory shock 1991;35(2):123-8.
1991: M N Teng; Ben Ho Park; H Koeppen; Kevin Tracey; B M Fendly; Hans Schreiber
Long-term inhibition of tumor growth by tumor necrosis factor in the absence of cachexia or T-cell immunity.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3535-9.
1991: R Bucala; Kevin Tracey; Anthony Cerami
Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.
The Journal of clinical investigation 1991;87(2):432-8.
1990: Kevin Tracey; S Morgello; B Koplin; T J Fahey; J Fox; A Aledo; K R Manogue; Anthony Cerami
Metabolic effects of cachectin/tumor necrosis factor are modified by site of production. Cachectin/tumor necrosis factor-secreting tumor in skeletal muscle induces chronic cachexia, while implantation in brain induces predominantly acute anorexia.
The Journal of clinical investigation 1990;86(6):2014-24.
1990: T J Fahey; B Sherry; Kevin Tracey; S van Deventer; W G Jones; J P Minei; S Morgello; G Tom Shires; A Cerami
Cytokine production in a model of wound healing: the appearance of MIP-1, MIP-2, cachectin/TNF and IL-1.
Cytokine 1990;2(2):92-9.
1990: Yuman Fong; Kevin Tracey; D G Hesse; J D Albert; Philip Barie; Stephen F Lowry
Influence of enterectomy on peripheral tissue glutamine efflux in critically ill patients.
Surgery 1990;107(3):321-6.
1990: Kevin Tracey; Stephen F Lowry
The role of cytokine mediators in septic shock.
Advances in surgery 1990;23():21-56.
1990: M A Marano; Yuman Fong; Lyle L Moldawer; H Wei; S E Calvano; Kevin Tracey; Philip Barie; K Manogue; A Cerami; G Tom Shires
Serum cachectin/tumor necrosis factor in critically ill patients with burns correlates with infection and mortality.
Surgery, gynecology & obstetrics 1990;170(1):32-8.
1990: Kevin Tracey; A Cerami
Metabolic responses to cachectin/TNF. A brief review.
Annals of the New York Academy of Sciences 1990;587():325-31.
1989: Yuman Fong; Kevin Tracey; Lyle L Moldawer; D G Hesse; K B Manogue; J S Kenney; A T Lee; G C Kuo; A C Allison; Stephen F Lowry
Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia.
The Journal of experimental medicine 1989;170(5):1627-33.
1989: Kevin Tracey; Anthony Cerami
The role of cachectin/tumor necrosis factor in AIDS.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1989;1(2):62-3.
1989: R P Richardson; C D Rhyne; Yuman Fong; D G Hesse; Kevin Tracey; M A Marano; Stephen F Lowry; A C Antonacci; S E Calvano
Peripheral blood leukocyte kinetics following in vivo lipopolysaccharide (LPS) administration to normal human subjects. Influence of elicited hormones and cytokines.
Annals of surgery 1989;210(2):239-45.
1989: M Rosenbaum; Yuman Fong; D G Hesse; Kevin Tracey; R L Hintz; Stephen F Lowry; J M Gertner
Intravenous refeeding blocks growth hormone (GH)-provoked rises in serum free fatty acids and blunting of somatotroph response to GH-releasing hormone in normal men.
The Journal of clinical endocrinology and metabolism 1989;69(2):310-6.
1989: J D Albert; D E Matthews; A Legaspi; Kevin Tracey; M Jeevanandam; Murray F Brennan; Stephen F Lowry
Exercise-mediated peripheral tissue and whole-body amino acid metabolism during intravenous feeding in normal man.
Clinical science (London, England : 1979) 1989;77(1):113-20.
1989: Kevin Tracey; H Vlassara; A Cerami
Cachectin/tumour necrosis factor.
Lancet 1989;1(8647):1122-6.
1989: Yuman Fong; M Rosenbaum; Kevin Tracey; G Raman; D G Hesse; D E Matthews; R L Leibel; J M Gertner; D A Fischman; Stephen F Lowry
Recombinant growth hormone enhances muscle myosin heavy-chain mRNA accumulation and amino acid accrual in humans.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3371-4.
1989: Yuman Fong; Lyle L Moldawer; M Marano; H Wei; A Barber; K Manogue; Kevin Tracey; G Kuo; D A Fischman; A Cerami
Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins.
The American journal of physiology 1989;256(3 Pt 2):R659-65.
1989: Kevin Tracey; A Cerami
Cachectin/tumor necrosis factor and other cytokines in infectious disease.
Current opinion in immunology 1989;1(3):454-61.
1989: Kevin Tracey; A Cerami
Studies of cachexia in parasitic infection.
Annals of the New York Academy of Sciences 1989;569():211-8.
1988: Kevin Tracey; S F Lowry; A Cerami
Cachetin/TNF-alpha in septic shock and septic adult respiratory distress syndrome.
The American review of respiratory disease 1988;138(6):1377-9.
1988: John Meyer; R W Yurt; R Duhaney; D G Hesse; Kevin Tracey; Yuman Fong; M Verma; G Tom Shires; P Dineen; Stephen F Lowry
Tumor necrosis factor-enhanced leukotriene B4 generation and chemotaxis in human neutrophils.
Archives of surgery (Chicago, Ill. : 1960) 1988;123(12):1454-8.
1988: J Meyer; R W Yurt; R Duhaney; D G Hesse; Kevin Tracey; Yuman Fong; D Richardson; S Calvano; P Dineen; G Tom Shires
Differential neutrophil activation before and after endotoxin infusion in enterally versus parenterally fed volunteers.
Surgery, gynecology & obstetrics 1988;167(6):501-9.
1988: Yuman Fong; M Rosenbaum; D G Hesse; Kevin Tracey; J Gertner; Stephen F Lowry
Influence of substrate background on peripheral tissue responses to growth hormone.
The Journal of surgical research 1988;44(6):702-8.
1988: Kevin Tracey; Stephen F Lowry; A Cerami
The pathophysiologic role of cachectin/TNF in septic shock and cachexia.
Annales de l'Institut Pasteur. Immunology 1988;139(3):311-7.
1988: Kevin Tracey; H Wei; K R Manogue; Yuman Fong; D G Hesse; H T Nguyen; G C Kuo; Bruce Beutler; R S Cotran; A Cerami
Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation.
The Journal of experimental medicine 1988;167(3):1211-27.
1988: Kevin Tracey; S F Lowry; A Cerami
Cachectin: a hormone that triggers acute shock and chronic cachexia.
The Journal of infectious diseases 1988;157(3):413-20.
1988: A Legaspi; J P Roberts; G D Horowitz; J D Albert; Kevin Tracey; G Tom Shires; Stephen F Lowry
Effect of starvation and total parenteral nutrition on electrolyte homeostasis in normal man.
JPEN. Journal of parenteral and enteral nutrition 1988;12(2):109-15.
1988: Yuman Fong; D G Hesse; Kevin Tracey; J D Albert; A Legaspi; Murray F Brennan; Stephen F Lowry
Submaximal exercise during intravenous hyperalimentation of depleted subjects.
Annals of surgery 1988;207(3):297-304.
1988: A Legaspi; J P Roberts; J D Albert; Kevin Tracey; G Tom Shires; Stephen F Lowry
The effect of starvation and total parenteral nutrition on skeletal muscle amino acid content and membrane potential difference in normal man.
Surgery, gynecology & obstetrics 1988;166(3):233-40.
1988: J D Albert; A Legaspi; G D Horowitz; S H Kubo; Kevin Tracey; robert cody; Stephen F Lowry
Preservation of functional aerobic capacity with daily submaximal exercise during intravenous feeding in hospitalized normal man.
World journal of surgery 1988;12(1):123-31.
1988: Kevin Tracey; A Legaspi; J D Albert; M Jeevanandam; D E Matthews; Murray F Brennan; Stephen F Lowry
Protein and substrate metabolism during starvation and parenteral refeeding.
Clinical science (London, England : 1979) 1988;74(2):123-32.
1988: D G Hesse; Kevin Tracey; Yuman Fong; K R Manogue; M A Palladino; A Cerami; G Tom Shires; Stephen F Lowry
Cytokine appearance in human endotoxemia and primate bacteremia.
Surgery, gynecology & obstetrics 1988;166(2):147-53.
1988: Kevin Tracey; Stephen F Lowry; A Cerami
Cachectin/TNF mediates the pathophysiological effects of bacterial endotoxin/lipopolysaccharide (LPS).
Progress in clinical and biological research 1988;272():77-88.
1987: Kevin Tracey; Yuman Fong; D G Hesse; K R Manogue; A T Lee; G C Kuo; Stephen F Lowry; A Cerami
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia.
Nature 1987;330(6149):662-4.
1987: G A Fantini; J P Roberts; Stephen F Lowry; J D Albert; Kevin Tracey; A Legaspi; J P Minei; J Chiao; G Tom Shires
Effect of hormonal and substrate backgrounds on cell membrane function in normal males.
Journal of applied physiology (Bethesda, Md. : 1985) 1987;63(3):1107-13.
1987: Stephen F Lowry; A Legaspi; J D Albert; G D Horowitz; Kevin Tracey
Thermogenic and nitrogen response to submaximal exercise in parenterally repleted normal man.
The American journal of clinical nutrition 1987;46(2):237-42.
1987: S E Calvano; J D Albert; A Legaspi; B C Organ; Kevin Tracey; Stephen F Lowry; G Tom Shires; A C Antonacci
Comparison of numerical and phenotypic leukocyte changes during constant hydrocortisone infusion in normal humans with those in thermally injured patients.
Surgery, gynecology & obstetrics 1987;164(6):509-20.
1987: Kevin Tracey; Stephen F Lowry; T J Fahey; J D Albert; Yuman Fong; D Hesse; Bruce Beutler; K R Manogue; S Calvano; H Wei
Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog.
Surgery, gynecology & obstetrics 1987;164(5):415-22.
1987: A Cerami; Kevin Tracey; S F Lowry; Bruce Beutler
Cachectin: a pluripotent hormone released during the host response to invasion.
Recent progress in hormone research 1987;43():99-112.
1987: Kevin Tracey; Stephen F Lowry; Anthony Cerami
Physiological responses to cachectin.
Ciba Foundation symposium 1987;131():88-108.
1986: J D Albert; A Legaspi; G D Horowitz; Kevin Tracey; Murray F Brennan; Stephen F Lowry
Extremity amino acid metabolism during starvation and intravenous refeeding in humans.
The American journal of physiology 1986;251(5 Pt 1):E604-10.
1986: Kevin Tracey; Bruce Beutler; Stephen F Lowry; J Merryweather; S Wolpe; I W Milsark; R J Hariri; T J Fahey; A Zentella; J D Albert
Shock and tissue injury induced by recombinant human cachectin.
Science (New York, N.Y.) 1986;234(4775):470-4.
1986: Kevin Tracey; S F Lowry; Bruce Beutler; A Cerami; J D Albert; G T Shires
Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential.
The Journal of experimental medicine 1986;164(4):1368-73.
1986: J D Albert; A Legaspi; G D Horowitz; Kevin Tracey; Murray F Brennan; Stephen F Lowry
Peripheral tissue metabolism in man with varied disease states and similar weight loss.
The Journal of surgical research 1986;40(4):374-81.
1984: Kevin Tracey; M J O'Brien; L F Williams; M Klibaner; P K George; C A Saravis; N Zamcheck
Signet ring carcinoma of the pancreas, a rare variant with very high CEA values. Immunohistologic comparison with adenocarcinoma.
Digestive diseases and sciences 1984;29(6):573-6.
1983: James O Menzoian; J C Sequeira; J E Doyle; NL Cantelmo; M Nowak; Kevin Tracey; R Zimmerman; P J Mozden
Therapeutic and clinical course of deep vein thrombosis.
American journal of surgery 1983;146(5):581-5.
1983: D Acker; B P Sachs; Kevin Tracey; W E Wise
Abruptio placentae associated with cocaine use.
American journal of obstetrics and gynecology 1983;146(2):220-1.
1983: Kevin Tracey; R Mutkoski; J A Lopez; W Franzblau; C Franzblau
Radioimmunoassay for methotrexate using hydroxyethylmethacrylate hydrogel.
Cancer chemotherapy and pharmacology 1983;10(2):96-9.