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Michael Trakselis

Research Profile

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Physiology

DNA Replication

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Publications

TOP 3
Robert J Bauer; Brian W Graham; Michael Trakselis
Novel interaction of the bacterial-Like DnaG primase with the MCM helicase in archaea.
Michael Trakselis; Brian W Graham
Biochemistry: Molecular hurdles cleared with ease.
Hsiang-Kai Lin; Susan F Chase; Linda Jen-Jacobson; Thomas M Laue; Michael Trakselis
Differential temperature-dependent multimeric assemblies of replication and repair polymerases on DNA increase processivity.

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All Publications

2013: Robert J Bauer; Brian W Graham; Michael Trakselis
Novel interaction of the bacterial-Like DnaG primase with the MCM helicase in archaea.
Journal of molecular biology 2013;425(8):1259-73.
2012: Michael Trakselis; Brian W Graham
Biochemistry: Molecular hurdles cleared with ease.
Nature 2012;492(7428):195-7.
2012: Hsiang-Kai Lin; Susan F Chase; Linda Jen-Jacobson; Thomas M Laue; Michael Trakselis
Differential temperature-dependent multimeric assemblies of replication and repair polymerases on DNA increase processivity.
Biochemistry 2012;51(37):7367-82.
2012: Robert J Bauer; Michael T Begley; Michael Trakselis
Kinetics and fidelity of polymerization by DNA polymerase III from Sulfolobus solfataricus.
Biochemistry 2012;51(9):1996-2007.
2011: Brian W Graham; Sanford H Leuba; Grant D Schauer; Michael Trakselis
Steric exclusion and wrapping of the excluded DNA strand occurs along discrete external binding paths during MCM helicase unwinding.
Nucleic acids research 2011;39(15):6585-95.
2011: Zhongfeng Zuo; Hsiang-Kai Lin; Michael Trakselis
Strand annealing and terminal transferase activities of a B-family DNA polymerase.
Biochemistry 2011;50(23):5379-90.
2010: Zhongfeng Zuo; Cory J Rodgers; Andrey L Mikheikin; Michael Trakselis
Characterization of a functional DnaG-type primase in archaea: implications for a dual-primase system.
Journal of molecular biology 2010;397(3):664-76.
2009: Andrey L Mikheikin; Hsiang-Kai Lin; Preeti Mehta; Linda Jen-Jacobson; Michael Trakselis
A trimeric DNA polymerase complex increases the native replication processivity.
Nucleic acids research 2009;37(21):7194-205.
2007: Eli Rothenberg; Michael Trakselis; Steve Bell; Taekjip Ha
MCM forked substrate specificity involves dynamic interaction with the 5'-tail.
The Journal of biological chemistry 2007;282(47):34229-34.
2005: Adam T McGeoch; Michael Trakselis; Ronald A Laskey; Steve Bell
Organization of the archaeal MCM complex on DNA and implications for the helicase mechanism.
Nature structural & molecular biology 2005;12(9):756-62.
2005: Michael Trakselis; Stephen C Alley; Faoud T Ishmael
Identification and mapping of protein-protein interactions by a combination of cross-linking, cleavage, and proteomics.
Bioconjugate chemistry 2005;16(4):741-50.
2005: Mona T Norcum; J Anthony Warrington; Michelle M Spiering; Faoud T Ishmael; Michael Trakselis; Stephen J Benkovic
Architecture of the bacteriophage T4 primosome: electron microscopy studies of helicase (gp41) and primase (gp61).
Proceedings of the National Academy of Sciences of the United States of America 2005;102(10):3623-6.
2005: Zhiquan Zhang; Michelle M Spiering; Michael Trakselis; Faoud T Ishmael; Jun Xi; Stephen J Benkovic; Gordon G Hammes
Assembly of the bacteriophage T4 primosome: single-molecule and ensemble studies.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3254-9.
2004: David Millar; Michael Trakselis; Stephen J Benkovic
On the solution structure of the T4 sliding clamp (gp45).
Biochemistry 2004;43(40):12723-7.
2004: Zhihao Zhuang; Michelle M Spiering; Anthony J Berdis; Michael Trakselis; Stephen J Benkovic
'Screw-cap' clamp loader proteins that thread.
Nature structural & molecular biology 2004;11(7):580-1.
2004: Michael Trakselis; Steve Bell
Molecular biology: the loader of the rings.
Nature 2004;429(6993):708-9.
2004: Jingsong Yang; Zhihao Zhuang; Rosa Maria Roccasecca; Michael Trakselis; Stephen J Benkovic
The dynamic processivity of the T4 DNA polymerase during replication.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(22):8289-94.
2003: Michael Trakselis; Rosa Maria Roccasecca; Jingsong Yang; Ann M Valentine; Stephen J Benkovic
Dissociative properties of the proteins within the bacteriophage T4 replisome.
The Journal of biological chemistry 2003;278(50):49839-49.
2003: Jingsong Yang; Michael Trakselis; Rosa Maria Roccasecca; Stephen J Benkovic
The application of a minicircle substrate in the study of the coordinated T4 DNA replication.
The Journal of biological chemistry 2003;278(50):49828-38.
2003: Michael Trakselis; Anthony J Berdis; Stephen J Benkovic
Examination of the role of the clamp-loader and ATP hydrolysis in the formation of the bacteriophage T4 polymerase holoenzyme.
Journal of molecular biology 2003;326(2):435-51.
2003: Faoud T Ishmael; Michael Trakselis; Stephen J Benkovic
Protein-protein interactions in the bacteriophage T4 replisome. The leading strand holoenzyme is physically linked to the lagging strand holoenzyme and the primosome.
The Journal of biological chemistry 2003;278(5):3145-52.
2001: Michael Trakselis; Stephen J Benkovic
Intricacies in ATP-dependent clamp loading: variations across replication systems.
Structure (London, England : 1993) 2001;9(11):999-1004.
2001: Stephen C Alley; Michael Trakselis; Uljana Mayer; Faoud T Ishmael; A Daniel Jones; Stephen J Benkovic
Building a replisome solution structure by elucidation of protein-protein interactions in the bacteriophage T4 DNA polymerase holoenzyme.
The Journal of biological chemistry 2001;276(42):39340-9.
2001: Michael Trakselis; Uljana Mayer; Faoud T Ishmael; Rosa Maria Roccasecca; Stephen J Benkovic
Dynamic protein interactions in the bacteriophage T4 replisome.
Trends in biochemical sciences 2001;26(9):566-72.
2001: Michael Trakselis; Stephen C Alley; Ernesto Abel-Santos; Stephen J Benkovic
Creating a dynamic picture of the sliding clamp during T4 DNA polymerase holoenzyme assembly by using fluorescence resonance energy transfer.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8368-75.