FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Francesc Aviles

Research Profile

Chemicals & Drugs

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Physiology

Protein Folding

Procedures

Disorders

Protein Denaturation

Phenomena

Co-author Network

Publications

TOP 3
Maday Alonso-del-Rivero; Francesc Canals; Maria Angeles Chavez; Julieta Delfin; Joaquin Diaz; Yamile González-González; Mey L Reytor; Monica Rodriguez-de-la-Vega; Sebastian A Trejo; Francesc Aviles
Tri-domain bifunctional inhibitor of metallocarboxypeptidases A and serine proteases isolated from marine annelid Sabellastarte magnifica.
Sílvia Bronsoms; Dusica Gabrijelcic-Geiger; David Pantoja-Uceda; Laura Sanglas; Jorge Santoro; Christian P Sommerhoff; Francesc Aviles; Joan L Arolas
Oxidative folding and structural analyses of a Kunitz-related inhibitor and its disulfide intermediates: functional implications.
L Sanglas; Joan L Arolas; Zuzana Valnickova; Francesc Aviles; Jan J Enghild; F Xavier Gomis-Rüth
Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Francesc Aviles (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Maday Alonso-del-Rivero; Francesc Canals; Maria Angeles Chavez; Julieta Delfin; Joaquin Diaz; Yamile González-González; Mey L Reytor; Monica Rodriguez-de-la-Vega; Sebastian A Trejo; Francesc Aviles
Tri-domain bifunctional inhibitor of metallocarboxypeptidases A and serine proteases isolated from marine annelid Sabellastarte magnifica.
The Journal of biological chemistry 2012;287(19):15427-38.
2011: Sílvia Bronsoms; Dusica Gabrijelcic-Geiger; David Pantoja-Uceda; Laura Sanglas; Jorge Santoro; Christian P Sommerhoff; Francesc Aviles; Joan L Arolas
Oxidative folding and structural analyses of a Kunitz-related inhibitor and its disulfide intermediates: functional implications.
Journal of molecular biology 2011;414(3):427-41.
2010: L Sanglas; Joan L Arolas; Zuzana Valnickova; Francesc Aviles; Jan J Enghild; F Xavier Gomis-Rüth
Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor.
Journal of thrombosis and haemostasis : JTH 2010;8(5):1056-65.
2009: David Pantoja-Uceda; Joan L Arolas; Francesc Aviles; Jorge Santoro; Salvador Ventura; Christian P Sommerhoff
Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
The Journal of biological chemistry 2009;284(51):35612-20.
2009: Joan L Arolas; Virginia Castillo; Sílvia Bronsoms; Francesc Aviles; Salvador Ventura
Designing out disulfide bonds of leech carboxypeptidase inhibitor: implications for its folding, stability and function.
Journal of molecular biology 2009;392(2):529-46.
2009: Maday Alonso-del-Rivero; Sebastian A Trejo; Mónica Rodríguez de la Vega; Yamile González; Silvia Bronsoms; Francesc Canals; Julieta Delfín; Joaquin Diaz; Francesc Aviles; María A Chávez
A novel metallocarboxypeptidase-like enzyme from the marine annelid Sabellastarte magnifica--a step into the invertebrate world of proteases.
The FEBS journal 2009;276(17):4875-90.
2009: Joan L Arolas; Laura Sanglas; Julia Lorenzo; Sílvia Bronsoms; Francesc Aviles
Insights into the two-domain architecture of the metallocarboxypeptidase inhibitor from the Ascaris parasite inferred from the mechanism of its oxidative folding.
Biochemistry 2009;48(34):8225-32.
2009: Laura Sanglas; Francesc Aviles; Robert Huber; F Xavier Gomis-Rüth; Joan L Arolas
Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):1743-7.
2009: Antoni Hermoso; Jordi Espadaler; E Enrique Querol; Francesc Aviles; Michael J E Sternberg; baldomero oliva; Narcis Fernandez-Fuentes
Including Functional Annotations and Extending the Collection of Structural Classifications of Protein Loops (ArchDB).
Bioinformatics and biology insights 2009;1():77-90.
2008: Joan L Arolas; David Pantoja-Uceda; Salvador Ventura; Francisco J Blanco; Francesc Aviles
The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
The Journal of biological chemistry 2008;283(40):27110-20.
2008: Laura Sanglas; Zuzana Valnickova; Joan L Arolas; Irantzu Pallarés; Tibisay Guevara; Maria Solà; Torsten Kristensen; Jan J Enghild; Francesc Aviles; F Xavier Gomis-Rüth
Structure of activated thrombin-activatable fibrinolysis inhibitor, a molecular link between coagulation and fibrinolysis.
Molecular cell 2008;31(4):598-606.
2008: David Pantoja-Uceda; Joan L Arolas; Pascal García; Eva López-Hernández; Daniel Padró; Francesc Aviles; Francisco Jose Blanco
The NMR structure and dynamics of the two-domain tick carboxypeptidase inhibitor reveal flexibility in its free form and stiffness upon binding to human carboxypeptidase B.
Biochemistry 2008;47(27):7066-78.
2008: Xabier Arias-Moreno; Joan L Arolas; Francesc Aviles; javier sancho; Salvador Ventura
Scrambled isomers as key intermediates in the oxidative folding of ligand binding module 5 of the low density lipoprotein receptor.
The Journal of biological chemistry 2008;283(20):13627-37.
2008: Montse Morell; Alba Espargaro; Francesc Aviles; Salvador Ventura
Study and selection of in vivo protein interactions by coupling bimolecular fluorescence complementation and flow cytometry.
Nature protocols 2008;3(1):22-33.
2008: Joan L Arolas; Sílvia Bronsoms; Francesc Aviles; Salvador Ventura; Christian P Sommerhoff
Oxidative folding of leech-derived tryptase inhibitor via native disulfide-bonded intermediates.
Antioxidants & redox signaling 2008;10(1):77-85.
2007: Elena Kalinina; Reeta Biswas; Iryna Berezniuk; Antoni Hermoso; Francesc Aviles; Lloyd D Fricker
A novel subfamily of mouse cytosolic carboxypeptidases.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(3):836-50.
2007: Natalia Sánchez de Groot; Teodor Parella; Francesc Aviles; Josep Vendrell; Salvador Ventura
Ile-phe dipeptide self-assembly: clues to amyloid formation.
Biophysical journal 2007;92(5):1732-41.
2007: Oscar Yanes; Francesc Aviles; Peter Roepstorff; Thomas J D Jørgensen
Exploring the "intensity fading" phenomenon in the study of noncovalent interactions by MALDI-TOF mass spectrometry.
Journal of the American Society for Mass Spectrometry 2007;18(2):359-67.
2007: Oscar Yanes; Josep Villanueva; Enrique Querol; Francesc Aviles
Detection of non-covalent protein interactions by 'intensity fading' MALDI-TOF mass spectrometry: applications to proteases and protease inhibitors.
Nature protocols 2007;2(1):119-30.
2007: Joan L Arolas; Josep Vendrell; Francesc Aviles; Lloyd D Fricker
Metallocarboxypeptidases: emerging drug targets in biomedicine.
Current pharmaceutical design 2007;13(4):349-66.
2006: Oscar Yanes; Alexis Nazabal; Ryan Wenzel; Renato Zenobi; Francesc Aviles
Detection of noncovalent complexes in biological samples by intensity fading and high-mass detection MALDI-TOF mass spectrometry.
Journal of proteome research 2006;5(10):2711-9.
2006: Jordi Espadaler; Enrique Querol; Francesc Aviles; baldomero oliva
Identification of function-associated loop motifs and application to protein function prediction.
Bioinformatics (Oxford, England) 2006;22(18):2237-43.
2006: Joan L Arolas; Sílvia Bronsoms; Salvador Ventura; Francesc Aviles; Juan J Calvete
Characterizing the tick carboxypeptidase inhibitor: molecular basis for its two-domain nature.
The Journal of biological chemistry 2006;281(32):22906-16.
2006: Alex Bayés; Mónica Rodríguez de la Vega; Josep Vendrell; Francesc Aviles; Maarten Jongsma; Jules Beekwilder
Response of the digestive system of Helicoverpa zea to ingestion of potato carboxypeptidase inhibitor and characterization of an uninhibited carboxypeptidase B.
Insect biochemistry and molecular biology 2006;36(8):654-64.
2006: Joan L Arolas; Francesc Aviles; Jui-Yoa Chang; Salvador Ventura
Folding of small disulfide-rich proteins: clarifying the puzzle.
Trends in biochemical sciences 2006;31(5):292-301.
2006: Natalia Sánchez de Groot; Francesc Aviles; Josep Vendrell; Salvador Ventura
Mutagenesis of the central hydrophobic cluster in Abeta42 Alzheimer's peptide. Side-chain properties correlate with aggregation propensities.
The FEBS journal 2006;273(3):658-68.
2005: Alex Bayés; Mireia Comellas-Bigler; Monica Rodríguez de la Vega; Klaus Maskos; Wolfram Bode; Francesc Aviles; Maarten Jongsma; Jules Beekwilder; Josep Vendrell
Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16602-7.
2005: Oscar Yanes; Josep Villanueva; Enrique Querol; Francesc Aviles
Functional screening of serine protease inhibitors in the medical leech Hirudo medicinalis monitored by intensity fading MALDI-TOF MS.
Molecular & cellular proteomics : MCP 2005;4(10):1602-13.
2005: Joan L Arolas; Grzegorz M Popowicz; Sílvia Bronsoms; Francesc Aviles; Robert Huber; Tad A Holak; Salvador Ventura
Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond.
Journal of molecular biology 2005;352(4):961-75.
2005: Narcis Fernandez-Fuentes; Enrique Querol; Francesc Aviles; Michael J E Sternberg; baldomero oliva
Prediction of the conformation and geometry of loops in globular proteins: testing ArchDB, a structural classification of loops.
Proteins 2005;60(4):746-57.
2005: Joan L Arolas; Loyola D'Silva; Grzegorz M Popowicz; Francesc Aviles; Tad A Holak; Salvador Ventura
NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor.
Structure (London, England : 1993) 2005;13(8):1193-202.
2005: Joan L Arolas; Grzegorz M Popowicz; Julia Lorenzo; Christian P Sommerhoff; Robert Huber; Francesc Aviles; Tad A Holak
The three-dimensional structures of tick carboxypeptidase inhibitor in complex with A/B carboxypeptidases reveal a novel double-headed binding mode.
Journal of molecular biology 2005;350(3):489-98.
2005: Joan L Arolas; Julia Lorenzo; Ana Rovira; Joaquim Castellà; Francesc Aviles; Christian P Sommerhoff
A carboxypeptidase inhibitor from the tick Rhipicephalus bursa: isolation, cDNA cloning, recombinant expression, and characterization.
The Journal of biological chemistry 2005;280(5):3441-8.
2004: Joan L Arolas; Sílvia Bronsoms; Julia Lorenzo; Francesc Aviles; Jui-Yoa Chang; Salvador Ventura
Role of kinetic intermediates in the folding of leech carboxypeptidase inhibitor.
The Journal of biological chemistry 2004;279(36):37261-70.
2004: Narcis Fernandez-Fuentes; Antoni Hermoso; Jordi Espadaler; Enrique Querol; Francesc Aviles; baldomero oliva
Classification of common functional loops of kinase super-families.
Proteins 2004;56(3):539-55.
2004: Daniel Aguilar; Francesc Aviles; Enrique Querol; Michael J E Sternberg
Analysis of phenetic trees based on metabolic capabilites across the three domains of life.
Journal of molecular biology 2004;340(3):491-512.
2004: Joan L Arolas; Julia Lorenzo; Ana Rovira; Josep Vendrell; Francesc Aviles; Salvador Ventura
Secondary binding site of the potato carboxypeptidase inhibitor. Contribution to its structure, folding, and biological properties.
Biochemistry 2004;43(24):7973-82.
2004: Alex Bayés; Theodoros Tsetsenis; Salvador Ventura; Josep Vendrell; Francesc Aviles; Georgia Sotiropoulou
Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation.
Biological chemistry 2004;385(6):517-24.
2004: Salvador Ventura; Jesús Zurdo; Saravanakumar Narayanan; Matilde Parreño; Bafalluy Mangues; Bernd Reif; Fabrizio Chiti; Elisa Giannoni; Christopher M Dobson; Francesc Aviles; Luis Serrano
Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7258-63.
2004: Jordi Espadaler; Narcis Fernandez-Fuentes; Antoni Hermoso; Enrique Querol; Francesc Aviles; Michael J E Sternberg; baldomero oliva
ArchDB: automated protein loop classification as a tool for structural genomics.
Nucleic acids research 2004;32(Database issue):D185-8.
2004: Antoni Hermoso; Daniel Aguilar; Francesc Aviles; Enrique Querol
TrSDB: a proteome database of transcription factors.
Nucleic acids research 2004;32(Database issue):D171-3.
2003: Daniel Aguilar; baldomero oliva; Francesc Aviles; Enrique Querol
SNOW: standard nomenclature wizard to help searching for (bio) chemical standardized names.
Bioinformatics (Oxford, England) 2003;19(18):2492-3.
2003: Sílvia Bronsoms; Josep Villanueva; Francesc Canals; Enrique Querol; Francesc Aviles
Analysis of the effect of potato carboxypeptidase inhibitor pro-sequence on the folding of the mature protein.
European journal of biochemistry / FEBS 2003;270(17):3641-50.
2003: Josep Villanueva; Gregorio Fernández-Ballester; Enrique Querol; Francesc Aviles; Luis Serrano
Ligand screening by exoproteolysis and mass spectrometry in combination with computer modelling.
Journal of molecular biology 2003;330(5):1039-48.
2003: Josep Villanueva; Oscar Yanes; Enrique Querol; Luis Serrano; Francesc Aviles
Identification of protein ligands in complex biological samples using intensity-fading MALDI-TOF mass spectrometry.
Analytical chemistry 2003;75(14):3385-95.
2003: Alex Bayés; Anka Sonnenschein; Xavier Daura; Josep Vendrell; Francesc Aviles
Procarboxypeptidase A from the insect pest Helicoverpa armigera and its derived enzyme. Two forms with new functional properties.
European journal of biochemistry / FEBS 2003;270(14):3026-35.
2003: Silvia Salamanca; Li Li; Josep Vendrell; Francesc Aviles; Jui-Yoa Chang
Major kinetic traps for the oxidative folding of leech carboxypeptidase inhibitor.
Biochemistry 2003;42(22):6754-61.
2002: Silvia Salamanca; Virtudes Villegas; Josep Vendrell; Li Li; Francesc Aviles; Jui-Yoa Chang
The unfolding pathway of leech carboxypeptidase inhibitor.
The Journal of biological chemistry 2002;277(20):17538-43.
2002: Patrick Aloy; baldomero oliva; Enrique Querol; Francesc Aviles; Robert B Russell
Structural similarity to link sequence space: new potential superfamilies and implications for structural genomics.
Protein science : a publication of the Protein Society 2002;11(5):1101-16.
2002: Suwen Wei; Sonia Segura; Josep Vendrell; Francesc Aviles; Edith Lanoue; Robert Day; Yun Feng; Lloyd D Fricker
Identification and characterization of three members of the human metallocarboxypeptidase gene family.
The Journal of biological chemistry 2002;277(17):14954-64.
2002: Daniel Aguilar; baldomero oliva; Francesc Aviles; Enrique Querol
TranScout: prediction of gene expression regulatory proteins from their sequences.
Bioinformatics (Oxford, England) 2002;18(4):597-607.
2001: Patrick Aloy; Enrique Querol; Francesc Aviles; Michael J E Sternberg
Automated structure-based prediction of functional sites in proteins: applications to assessing the validity of inheriting protein function from homology in genome annotation and to protein docking.
Journal of molecular biology 2001;311(2):395-408.
2001: Patrick Aloy; V Companys; Josep Vendrell; Francesc Aviles; Lloyd D Fricker; Miquel Coll; F Xavier Gomis-Rüth
The crystal structure of the inhibitor-complexed carboxypeptidase D domain II and the modeling of regulatory carboxypeptidases.
The Journal of biological chemistry 2001;276(19):16177-84.
2001: G Venhudova; Francesc Canals; Enrique Querol; Francesc Aviles
Mutations in the N- and C-terminal tails of potato carboxypeptidase inhibitor influence its oxidative refolding process at the reshuffling stage.
The Journal of biological chemistry 2001;276(15):11683-90.
2000: MA Martí-Renom; R H Stote; Enrique Querol; Francesc Aviles; M Karplus
Structures of scrambled disulfide forms of the potato carboxypeptidase inhibitor predicted by molecular dynamics simulations with constraints.
Proteins 2000;40(3):482-93.
2000: Jui-Yoa Chang; Li Li; Francesc Canals; Francesc Aviles
The unfolding pathway and conformational stability of potato carboxypeptidase inhibitor.
The Journal of biological chemistry 2000;275(19):14205-11.
1998: Patrick Aloy; G Moont; HA Gabb; Enrique Querol; Francesc Aviles; Michael J E Sternberg
Modelling repressor proteins docking to DNA.
Proteins 1998;33(4):535-49.
1998: Michael J E Sternberg; Patrick Aloy; HA Gabb; RM Jackson; G Moont; Enrique Querol; Francesc Aviles
A computational system for modelling flexible protein-protein and protein-DNA docking.
Proceedings / ... International Conference on Intelligent Systems for Molecular Biology ; ISMB. International Conference on Intelligent Systems for Molecular Biology 1998;6():183-92.
1992: M Billeter; Josep Vendrell; Gerhard Wider; Francesc Aviles; Miquel Coll; Alicia Guasch; Robert Huber; K Wuthrich
Comparison of the NMR solution structure with the X-ray crystal structure of the activation domain from procarboxypeptidase B.
Journal of biomolecular NMR 1992;2(1):1-10.
1991: Francisco Conejero-Lara; Pedro L Mateo; Francesc Aviles; Jose M Sanchez-Ruiz
Effect of Zn2+ on the thermal denaturation of carboxypeptidase B.
Biochemistry 1991;30(8):2067-72.
1989: R Pascual; F J Burgos; M Salva; F Soriano; E Mendez; Francesc Aviles
Purification and properties of five different forms of human procarboxypeptidases.
European journal of biochemistry / FEBS 1989;179(3):609-16.
1988: Jose M Sanchez-Ruiz; J L Lopez-Lacomba; Pedro L Mateo; M Vilanova; M A Serra; Francesc Aviles
Analysis of the thermal unfolding of porcine procarboxypeptidase A and its functional pieces by differential scanning calorimetry.
European journal of biochemistry / FEBS 1988;176(1):225-30.
1982: Josep Vendrell; Francesc Aviles; B San Segundo; C M Cuchillo
Isolation and re-association of the subunits from the pro-(carboxypeptidase A)-pro-(proteinase E) binary complex from pgi pancreas.
The Biochemical journal 1982;205(2):449-52.
1982: E I Tiktopulo; P L Privalov; T I Odintsova; T M Ermokhina; I A Krasheninnikov; Francesc Aviles; P D Cary; Colyn Crane-Robinson
The central tryptic fragment of histones H1 and H5 is a fully compacted domain and is the only folded region in the polypeptide chain. A thermodynamic study.
European journal of biochemistry / FEBS 1982;122(2):327-31.
1980: J Allan; P G Hartman; Colyn Crane-Robinson; Francesc Aviles
The structure of histone H1 and its location in chromatin.
Nature 1980;288(5792):675-9.