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Stefan Leitgeb

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Ulrich Roessl; Johanna Wiesbauer; Ruth Birner-Gruenberger; Stefan Leitgeb; Bernd Nidetzky
Non-native aggregation of recombinant human granulocyte-colony stimulating factor under simulated process stress conditions.
Birgit Unterweger; Thomas Stoisser; Ruth Birner-Gruenberger; Stefan Leitgeb; Bernd Nidetzky
Engineering of Aerococcus viridans L-lactate oxidase for site-specific PEGylation: characterization and selective bioorthogonal modification of a S218C mutant.
Stefan Leitgeb; Bernd Nidetzky
Enzyme catalytic promiscuity: the nonheme Fe2+ center of beta-diketone-cleaving dioxygenase Dke1 promotes hydrolysis of activated esters.

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2012: Ulrich Roessl; Johanna Wiesbauer; Ruth Birner-Gruenberger; Stefan Leitgeb; Bernd Nidetzky
Non-native aggregation of recombinant human granulocyte-colony stimulating factor under simulated process stress conditions.
Biotechnology journal 2012;7(8):1014-24.
2012: Birgit Unterweger; Thomas Stoisser; Ruth Birner-Gruenberger; Stefan Leitgeb; Bernd Nidetzky
Engineering of Aerococcus viridans L-lactate oxidase for site-specific PEGylation: characterization and selective bioorthogonal modification of a S218C mutant.
Bioconjugate chemistry 2012;23(7):1406-14.
2010: Stefan Leitgeb; Bernd Nidetzky
Enzyme catalytic promiscuity: the nonheme Fe2+ center of beta-diketone-cleaving dioxygenase Dke1 promotes hydrolysis of activated esters.
Chembiochem : a European journal of chemical biology 2010;11(4):502-5.
2009: Stefan Leitgeb; Grit D Straganz; Bernd Nidetzky
Functional characterization of an orphan cupin protein from Burkholderia xenovorans reveals a mononuclear nonheme Fe2+-dependent oxygenase that cleaves beta-diketones.
The FEBS journal 2009;276(20):5983-97.
2009: Stefan Leitgeb; Grit D Straganz; Bernd Nidetzky
Biochemical characterization and mutational analysis of the mononuclear non-haem Fe2+ site in Dke1, a cupin-type dioxygenase from Acinetobacter johnsonii.
The Biochemical journal 2009;418(2):403-11.
2008: Stefan Leitgeb; Bernd Nidetzky
Structural and functional comparison of 2-His-1-carboxylate and 3-His metallocentres in non-haem iron(II)-dependent enzymes.
Biochemical Society transactions 2008;36(Pt 6):1180-6.
2006: Regina Kratzer; Stefan Leitgeb; David K Wilson; Bernd Nidetzky
Probing the substrate binding site of Candida tenuis xylose reductase (AKR2B5) with site-directed mutagenesis.
The Biochemical journal 2006;393(Pt 1):51-8.
2005: Stefan Leitgeb; Barbara Petschacher; David K Wilson; Bernd Nidetzky
Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274-->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+ and NADP+.
FEBS letters 2005;579(3):763-7.
2005: Barbara Petschacher; Stefan Leitgeb; Kathryn L Kavanagh; David K Wilson; Bernd Nidetzky
The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography.
The Biochemical journal 2005;385(Pt 1):75-83.