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Charles Cairns

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Sarah M Perman; Anna Marie Chang; Judd E Hollander; David F Gaieski; Stephen Trzeciak; Robert Birkhahn; Ronny Otero; Tiffany M Osborn; Eugene Moretti; H Bryant Nguyen; Kyle J Gunnerson; David Milzman; Munish Goyal; Charles Cairns; Long Ngo; Emanuel P Rivers; Nathan I Shapiro
Relationship between B-type natriuretic peptide and adverse outcome in patients with clinical evidence of sepsis presenting to the emergency department.
Nathan I Shapiro; Stephen Trzeciak; Judd E Hollander; Robert Birkhahn; Ronny Otero; Tiffany M Osborn; Eugene Moretti; H Bryant Nguyen; Kyle J Gunnerson; David Milzman; David F Gaieski; Munish Goyal; Charles Cairns; Kenneth Kupfer; Seok-Won Lee; Emanuel P Rivers
The diagnostic accuracy of plasma neutrophil gelatinase-associated lipocalin in the prediction of acute kidney injury in emergency department patients with suspected sepsis.
Seth Glickman; Charles Cairns; Anita Y Chen; Eric D Peterson; Matthew T Roe
Delays in fibrinolysis as primary reperfusion therapy for acute ST-segment elevation myocardial infarction.

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All Publications

2011: Sarah M Perman; Anna Marie Chang; Judd E Hollander; David F Gaieski; Stephen Trzeciak; Robert Birkhahn; Ronny Otero; Tiffany M Osborn; Eugene Moretti; H Bryant Nguyen; Kyle J Gunnerson; David Milzman; Munish Goyal; Charles Cairns; Long Ngo; Emanuel P Rivers; Nathan I Shapiro
Relationship between B-type natriuretic peptide and adverse outcome in patients with clinical evidence of sepsis presenting to the emergency department.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2011;18(2):219-22.
2010: Nathan I Shapiro; Stephen Trzeciak; Judd E Hollander; Robert Birkhahn; Ronny Otero; Tiffany M Osborn; Eugene Moretti; H Bryant Nguyen; Kyle J Gunnerson; David Milzman; David F Gaieski; Munish Goyal; Charles Cairns; Kenneth Kupfer; Seok-Won Lee; Emanuel P Rivers
The diagnostic accuracy of plasma neutrophil gelatinase-associated lipocalin in the prediction of acute kidney injury in emergency department patients with suspected sepsis.
Annals of emergency medicine 2010;56(1):52-59.e1.
2010: Seth Glickman; Charles Cairns; Anita Y Chen; Eric D Peterson; Matthew T Roe
Delays in fibrinolysis as primary reperfusion therapy for acute ST-segment elevation myocardial infarction.
American heart journal 2010;159(6):998-1004.e2.
2010: Seth Glickman; Charles Cairns; Ronny M Otero; Christopher W Woods; Ephraim L Tsalik; Raymond J Langley; Jennifer C Van Velkinburgh; Lawrence Park; Lawrence T Glickman; Vance G Fowler; Stephen F Kingsmore; Emanuel P Rivers
Disease progression in hemodynamically stable patients presenting to the emergency department with sepsis.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2010;17(4):383-90.
2010: Michael A LaMantia; Timothy Plattsmills; Kevin Biese; Christine Khandelwal; Cory Forbach; Charles Cairns; Jan Busby-Whitehead; John S Kizer
Predicting hospital admission and returns to the emergency department for elderly patients.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2010;17(3):252-9.
2010: Timothy Plattsmills; Debbie A Travers; Kevin Biese; Brenda McCall; Steve Kizer; Michael LaMantia; Jan Busby-Whitehead; Charles Cairns
Accuracy of the Emergency Severity Index triage instrument for identifying elder emergency department patients receiving an immediate life-saving intervention.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2010;17(3):238-43.
2010: Gregory Mears; Drexdal Pratt; Seth Glickman; Jane H Brice; lawrence glickman; Jose G Cabañas; Charles Cairns
The North Carolina EMS Data System: a comprehensive integrated emergency medical services quality improvement program.
Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors 2010;14(1):85-94.
2010: Ephraim L Tsalik; Daphne Jones; Bradly Nicholson; Lynette Waring; Oliver Liesenfeld; Lawrence Park; Seth Glickman; Lauren B Caram; Raymond J Langley; Jennifer C Van Velkinburgh; Charles Cairns; Emanuel P Rivers; Ronny M Otero; Stephen F Kingsmore; Tahaniyat Lalani; Vance G Fowler; Christopher W Woods
Multiplex PCR to diagnose bloodstream infections in patients admitted from the emergency department with sepsis.
Journal of clinical microbiology 2010;48(1):26-33.
2009: Susan B Promes; Saumil M Chudgar; Colleen O'Connor Grochowski; Philip Shayne; Jennifer Isenhour; Seth Glickman; Charles Cairns
Gaps in procedural experience and competency in medical school graduates.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2009;16 Suppl 2():S58-62.
2009: James W Hoekstra; Brian J O'Neill; Yuri B Pride; Cedric Lefebvre; Deborah B Diercks; W Frank Peacock; Gregory J Fermann; C Michael Gibson; Duane Pinto; Jim Giglio; Abhinav Chandra; Charles Cairns; Marvin A Konstam; Joe Massaro; Mitchell Krucoff
Acute detection of ST-elevation myocardial infarction missed on standard 12-Lead ECG with a novel 80-lead real-time digital body surface map: primary results from the multicenter OCCULT MI trial.
Annals of emergency medicine 2009;54(6):779-788.e1.
2009: D Mark Courtney; Robert W Neumar; Arjun K Venkatesh; Amy H Kaji; Charles Cairns; Eric Lavonas; Lynne D Richardson
Unique characteristics of emergency care research: scope, populations, and infrastructure.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2009;16(10):990-4.
2009: Alexander T Limkakeng; Seth Glickman; Charles Cairns; Abhinav Chandra
Unsuspected pulmonary embolism in observation unit patients.
The western journal of emergency medicine 2009;10(3):130-4.
2009: J Perren Cobb; Charles Cairns; Eileen Bulger; Hector R Wong; Polly E Parsons; Derek C Angus; Nina T Gentile; David B Hoyt; Debra Anne Schwinn; jeanine wiener-kronish; Jeffrey S Upperman
The United States critical illness and injury trials group: an introduction.
The Journal of trauma 2009;67(2 Suppl):S159-60.
2009: Gregory Mears; Seth Glickman; Fionna Moore; Charles Cairns
Data based integration of critical illness and injury patient care from EMS to emergency department to intensive care unit.
Current opinion in critical care 2009;15(4):284-9.
2009: Abhinav Chandra; Seth Glickman; Fang-Shu Ou; W Frank Peacock; James K McCord; Charles Cairns; eric peterson; Erik Ohman; W Brian Gibler; Matthew T Roe
An analysis of the Association of Society of Chest Pain Centers Accreditation to American College of Cardiology/American Heart Association non-ST-segment elevation myocardial infarction guideline adherence.
Annals of emergency medicine 2009;54(1):17-25.
2009: Adam J Singer; Henry C Thode; Gary B Green; Robert Birkhahn; Nathan I Shapiro; Charles Cairns; Brigitte M Baumann; Richard Aghababian; Douglas Char; Judd E Hollander
The incremental benefit of a shortness-of-breath biomarker panel in emergency department patients with dyspnea.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2009;16(6):488-94.
2009: Seth Glickman; John G McHutchison; eric peterson; Charles Cairns; Robert A Harrington; Robert M Califf; Kevin Schulman
Ethical and scientific implications of the globalization of clinical research.
The New England journal of medicine 2009;360(8):816-23.
2009: Nathan I Shapiro; Stephen Trzeciak; Judd E Hollander; Robert Birkhahn; Ronny Otero; Tiffany M Osborn; Eugene Moretti; H Bryant Nguyen; Kyle J Gunnerson; David Milzman; David F Gaieski; Munish Goyal; Charles Cairns; Long Ngo; Emanuel P Rivers
A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis.
Critical care medicine 2009;37(1):96-104.
2008: Matthew T Roe; Anita Y Chen; Elizabeth R DeLong; William E Boden; James E Calvin; Charles Cairns; Sidney C Smith; Charles V Pollack; Ralph G Brindis; Robert M Califf; W Brian Gibler; Erik Ohman; eric peterson
Patterns of transfer for patients with non-ST-segment elevation acute coronary syndrome from community to tertiary care hospitals.
American heart journal 2008;156(1):185-92.
2008: Kathleen J Clem; Susan B Promes; Seth Glickman; Anand Shah; Michelle A Finkel; Ricardo Pietrobon; Charles Cairns
Factors enhancing career satisfaction among female emergency physicians.
Annals of emergency medicine 2008;51(6):723-728.e8.
2008: Seth Glickman; Kevin J Anstrom; Li Lin; Abhinav Chandra; Daniel T Laskowitz; Christopher W Woods; Debra H Freeman; Monica Kraft; Laura M Beskow; Kevin P Weinfurt; Kevin Schulman; Charles Cairns
Challenges in enrollment of minority, pediatric, and geriatric patients in emergency and acute care clinical research.
Annals of emergency medicine 2008;51(6):775-780.e3.
2008: Seth Glickman; Kevin Schulman; Eric D Peterson; Michael B Hocker; Charles Cairns
Evidence-based perspectives on pay for performance and quality of patient care and outcomes in emergency medicine.
Annals of emergency medicine 2008;51(5):622-31.
2008: Seth Glickman; Kevin Schulman; Charles Cairns
Primary PCI in ST-segment elevation myocardial infarction.
The New England journal of medicine 2008;358(16):1751-2; author reply 1752-3.
2008: Mark D Piehl; James E Manning; Shane L McCurdy; Tim S Rhue; Keith Kocis; Charles Cairns; Bruce A Cairns
Pulse contour cardiac output analysis in a piglet model of severe hemorrhagic shock.
Critical care medicine 2008;36(4):1189-95.
2008: Abhinav Chandra; Ronny Otero; Debra Freeman; Charles Cairns
BNP-mediated vasodilatation for dialysis-dependent patient with acute heart failure syndrome in the emergency department.
Renal failure 2008;30(1):45-50.
2008: Monica Kraft; Kenneth B Adler; Jennifer L Ingram; Anne L Crews; T P Atkinson; Charles Cairns; Duncan C Krause; Hong Wei Chu
Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma.
The European respiratory journal 2008;31(1):43-6.
2007: Henry Halperin; Norman Paradis; Vincent N Mosesso; Graham Nichol; Michael R Sayre; Joseph P Ornato; Mike Gerardi; Vinay M Nadkarni; Robert A Berg; Lance Becker; Mark Siegler; Megan Collins; Charles Cairns; Michelle H Biros; Terry Vanden Hoek; Mary Ann Peberdy
Recommendations for implementation of community consultation and public disclosure under the Food and Drug Administration's "Exception from informed consent requirements for emergency research": a special report from the American Heart Association Emergency Cardiovascular Care Committee and Council on Cardiopulmonary, Perioperative and Critical Care: endorsed by the American College of Emergency Physicians and the Society for Academic Emergency Medicine.
Circulation 2007;116(16):1855-63.
2007: Brian J O'connor; Claes-Göran AH Löfdahl; Meyer Balter; Andrew Szczeklik; Louis-Philippe Boulet; Charles Cairns
Zileuton added to low-dose inhaled beclomethasone for the treatment of moderate to severe persistent asthma.
Respiratory medicine 2007;101(6):1088-96.
2007: W Berger; M T M De Chandt; Charles Cairns
Zileuton: clinical implications of 5-Lipoxygenase inhibition in severe airway disease.
International journal of clinical practice 2007;61(4):663-76.
2007: Charles Cairns
Food and Drug Administration public hearing on the conduct of emergency clinical research: testimony of the American College of Emergency Physicians.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2007;14(4):e31-2.
2007: David J Berkoff; Charles Cairns; Leon D Sanchez; Claude T Moorman
Heart rate variability in elite American track-and-field athletes.
Journal of strength and conditioning research / National Strength & Conditioning Association 2007;21(1):227-31.
2006: Monica Kraft; Charles Cairns; Misoo C Ellison; Juno Pak; Charles Irvin; Sally Wenzel
Improvements in distal lung function correlate with asthma symptoms after treatment with oral montelukast.
Chest 2006;130(6):1726-32.
2006: Steven N Vaslef; Charles Cairns; John M Falletta
Ethical and regulatory challenges associated with the exception from informed consent requirements for emergency research: from experimental design to institutional review board approval.
Archives of surgery (Chicago, Ill. : 1960) 2006;141(10):1019-23; discussion 1024.
2006: Charles Cairns
Acute asthma exacerbations: phenotypes and management.
Clinics in chest medicine 2006;27(1):99-108, vi-vii.
2003: Michael Yaron; Susan Niermeyer; Kjell Norwood Lindgren; Benjamin Honigman; John D Strain; Charles Cairns
Physiologic response to moderate altitude exposure among infants and young children.
High altitude medicine & biology 2003;4(1):53-9.
2002: Charles Cairns; Paul E Pepe; Lance B Becker
Resuscitation of cells and systems: the PULSE research initiative. Post Resuscitative and Initial Utility of Life Saving Efforts.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2002;9(6):613-4.
2002: Brian D Shames; Hazel H Barton; Leonid L Reznikov; Charles Cairns; Anirban Banerjee; Alden H Harken; Xianzhong Meng
Ischemia alone is sufficient to induce TNF-alpha mRNA and peptide in the myocardium.
Shock (Augusta, Ga.) 2002;17(2):114-9.
2001: Charles Cairns
Rude unhinging of the machinery of life: metabolic approaches to hemorrhagic shock.
Current opinion in critical care 2001;7(6):437-43.
2001: Kennon Heard; B S Cain; Richard C Dart; Charles Cairns
Tricyclic antidepressants directly depress human myocardial mechanical function independent of effects on the conduction system.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2001;8(12):1122-7.
2001: Robert E Hill; Kennon Heard; Gregory M Bogdan; Charles Cairns; Richard C Dart
Attenuation of verapamil-induced myocardial toxicity in an ex-vivo rat model using a verapamil-specific ovine immunoglobin.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2001;8(10):950-5.
2001: Kennon Heard; Robert E Hill; Charles Cairns; Richard C Dart
Calcium neutralizes fluoride bioavailability in a lethal model of fluoride poisoning.
Journal of toxicology. Clinical toxicology 2001;39(4):349-53.
2000: Charles Cairns; Norman Paradis
Empiric lidocaine: Déjà vu (all over again?)
Annals of emergency medicine 2000;36(6):626-7.
2000: Thomas N Robinson; T D Morrell; Benjamin J Pomerantz; Julie K Heimbach; Charles Cairns; Alden H Harken
Therapeutically accessible clinical cardiac states.
Journal of the American College of Surgeons 2000;191(4):452-63.
2000: Charles Cairns; Edward A Panacek; Alden H Harken; Anirban Banerjee
Bench to bedside: tumor necrosis factor-alpha: from inflammation to resuscitation.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2000;7(8):930-41.
2000: Edward A Panacek; Charles Cairns
The emergency physician as integrative physiologist: inauguration of the academic emergency medicine "bench to bedside" series.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2000;7(3):284.
1999: James T Niemann; Charles Cairns
Hyperkalemia and ionized hypocalcemia during cardiac arrest and resuscitation: possible culprits for postcountershock arrhythmias?
Annals of emergency medicine 1999;34(1):1-7.
1999: Nirmal Veeramachaneni; Alden H Harken; Charles Cairns
Clinical implications of hemoglobin as a nitric oxide carrier.
Archives of surgery (Chicago, Ill. : 1960) 1999;134(4):434-7.
1999: C V Pollack; Charles Cairns
The Emergency Medicine Foundation: 25 years of advancing education and research.
Annals of emergency medicine 1999;33(4):448-50.
1999: J Cochrane; B T Williams; A Banerjee; A H Harken; Thomas J Burke; Charles Cairns; Joseph Shapiro
Ischemic preconditioning attenuates functional, metabolic, and morphologic injury from ischemic acute renal failure in the rat.
Renal failure 1999;21(2):135-45.
1999: E M Ketcham; Charles Cairns
Hemoglobin-based oxygen carriers: development and clinical potential.
Annals of emergency medicine 1999;33(3):326-37.
1998: Charles Cairns
Apoptosis: only the good die young?
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 1998;5(10):948-50.
1998: Charles Cairns; James Walther; Alden H Harken; Anirban Banerjee
Mitochondrial oxidative phosphorylation thermodynamic efficiencies reflect physiological organ roles.
The American journal of physiology 1998;274(5 Pt 2):R1376-83.
1998: Charles Cairns; J T Niemann
Hemodynamic effects of repeated doses of epinephrine after prolonged cardiac arrest and CPR: preliminary observations in an animal model.
Resuscitation 1998;36(3):181-5.
1998: Charles Cairns; H G Garrison; Jerris R Hedges; D L Schriger; T D Valenzuela
Development of new methods to assess the outcomes of emergency care.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 1998;5(2):157-61.
1997: Charles Cairns
Implications of basic science research for emergency medicine.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 1997;4(12):1172.
1997: Charles Cairns; A A Ferroggiaro; James Walther; Alden H Harken; Anirban Banerjee
Postischemic administration of succinate reverses the impairment of oxidative phosphorylation after cardiac ischemia and reperfusion injury.
Circulation 1997;96(9 Suppl):II-260-5.
1997: T F Rehring; P R Bender; Charles Cairns; K Joo; R S Friese; Joseph Shapiro; Joseph C Cleveland; Anirban Banerjee
Different preconditioning stimuli invoke disparate electromechanical and energetic responses to global ischemia in rat hearts.
Canadian journal of physiology and pharmacology 1997;75(4):335-42.
1997: Charles Cairns; Frederick A Moore; J B Haenel; B L Gallea; J P Ortner; S J Rose; Ernest E Moore
Evidence for early supply independent mitochondrial dysfunction in patients developing multiple organ failure after trauma.
The Journal of trauma 1997;42(3):532-6.
1996: Charles Cairns; Monica Kraft
Magnesium attenuates the neutrophil respiratory burst in adult asthmatic patients.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 1996;3(12):1093-7.
1996: R V Aghababian; William G Barsan; W H Bickell; Michelle H Biros; C G Brown; Charles Cairns; M L Callaham; D L Carden; W H Cordell; R C Dart; S H Dronen; H G Garrison; Lewis Goldfrank; Jerris R Hedges; Gabor D Kelen; A L Kellermann; L M Lewis; R G Lewis; L J Ling; J A Marx; J B McCabe; A B Sanders; D L Schriger; D P Sklar
Research directions in emergency medicine.
The American journal of emergency medicine 1996;14(7):681-3.
1996: M Yaron; P Padyk; M Hutsinpiller; Charles Cairns
Utility of the expiratory capnogram in the assessment of bronchospasm.
Annals of emergency medicine 1996;28(4):403-7.
1995: P L Henneman; D M Birnbaumer; Charles Cairns
Measles pneumonitis.
Annals of emergency medicine 1995;26(3):278-82.
1995: M Yaron; M H Erin; W Huffer; Charles Cairns
Efficacy of tissue glue for laceration repair in an animal model.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 1995;2(4):259-63.
1993: Anirban Banerjee; C Locke-Winter; K B Rogers; Max B Mitchell; E C Brew; Charles Cairns; Denis D Bensard; Alden H Harken
Preconditioning against myocardial dysfunction after ischemia and reperfusion by an alpha 1-adrenergic mechanism.
Circulation research 1993;73(4):656-70.
1992: James T Niemann; Charles Cairns; J Sharma; R J Lewis
Treatment of prolonged ventricular fibrillation. Immediate countershock versus high-dose epinephrine and CPR preceding countershock.
Circulation 1992;85(1):281-7.
1992: Charles Cairns; J T Niemann; Harry P Selker; M M Laks
Computerized version of the time-insensitive predictive instrument. Use of the Q wave, ST-segment, T wave, and patient history in the diagnosis of acute myocardial infarction by the computerized ECG.
Journal of electrocardiology 1992;24 Suppl():46-9.
1991: Charles Cairns; James T Niemann; P C Pelikan; J Sharma
Ionized hypocalcemia during prolonged cardiac arrest and closed-chest CPR in a canine model.
Annals of emergency medicine 1991;20(11):1178-82.
1991: Charles Cairns; James T Niemann
Intravenous adenosine in the emergency department management of paroxysmal supraventricular tachycardia.
Annals of emergency medicine 1991;20(7):717-21.