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Lenka Švihálková-Šindlerová

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Lenka Švihálková-Šindlerová; Vendula Foltinová; Alena Vaculová; Viktor Horváth; Karel Soucek; Petr Sova; Jirina Hofmanová; Alois Kozubík
LA-12 overcomes confluence-dependent resistance of HT-29 colon cancer cells to Pt (II) compounds.
Miroslav Machala; Lenka Švihálková-Šindlerová; K Pencíková; P Krcmár; Jan Topinka; A Milcová; Z Nováková; Alois Kozubík; Jan Vondrácek
Effects of methylated chrysenes on AhR-dependent and -independent toxic events in rat liver epithelial cells.
Jan Vondrácek; Lenka Švihálková-Šindlerová; Katerina Pencíková; Sona Marvanová; Pavel Krcmár; Miroslav Ciganek; Jirí Neca; James E Trosko; Brad L Upham; Alois Kozubík; Miroslav Machala
Concentrations of methylated naphthalenes, anthracenes, and phenanthrenes occurring in Czech river sediments and their effects on toxic events associated with carcinogenesis in rat liver cell lines.

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All Publications

2010: Lenka Švihálková-Šindlerová; Vendula Foltinová; Alena Vaculová; Viktor Horváth; Karel Soucek; Petr Sova; Jirina Hofmanová; Alois Kozubík
LA-12 overcomes confluence-dependent resistance of HT-29 colon cancer cells to Pt (II) compounds.
Anticancer research 2010;30(4):1183-8.
2008: Miroslav Machala; Lenka Švihálková-Šindlerová; K Pencíková; P Krcmár; Jan Topinka; A Milcová; Z Nováková; Alois Kozubík; Jan Vondrácek
Effects of methylated chrysenes on AhR-dependent and -independent toxic events in rat liver epithelial cells.
Toxicology 2008;247(2-3):93-101.
2007: Jan Vondrácek; Lenka Švihálková-Šindlerová; Katerina Pencíková; Sona Marvanová; Pavel Krcmár; Miroslav Ciganek; Jirí Neca; James E Trosko; Brad L Upham; Alois Kozubík; Miroslav Machala
Concentrations of methylated naphthalenes, anthracenes, and phenanthrenes occurring in Czech river sediments and their effects on toxic events associated with carcinogenesis in rat liver cell lines.
Environmental toxicology and chemistry / SETAC 2007;26(11):2308-16.
2007: Viktor Horváth; Karel Soucek; Lenka Švihálková-Šindlerová; Jan Vondrácek; Olga Blanárová; Jirina Hofmanová; Petr Sova; Alois Kozubík
Different cell cycle modulation following treatment of human ovarian carcinoma cells with a new platinum(IV) complex vs cisplatin.
Investigational new drugs 2007;25(5):435-43.
2007: Jirina Zatloukalová; Lenka Švihálková-Šindlerová; Alois Kozubík; Pavel Krcmár; Miroslav Machala; Jan Vondrácek
beta-Naphthoflavone and 3'-methoxy-4'-nitroflavone exert ambiguous effects on Ah receptor-dependent cell proliferation and gene expression in rat liver 'stem-like' cells.
Biochemical pharmacology 2007;73(10):1622-34.
2007: Lenka Švihálková-Šindlerová; Miroslav Machala; Katerina Pencíková; Sona Marvanová; Jirí Neca; Jan Topinka; Oksana Sevastyanova; Alois Kozubík; Jan Vondrácek
Dibenzanthracenes and benzochrysenes elicit both genotoxic and nongenotoxic events in rat liver 'stem-like' cells.
Toxicology 2007;232(1-2):147-59.
2007: Zdenek Andrysík; Jan Vondrácek; Miroslav Machala; Pavel Krcmár; Lenka Švihálková-Šindlerová; Anne Kranz; Carsten Weiss; Dagmar Faust; Alois Kozubík; Cornelia Dietrich
The aryl hydrocarbon receptor-dependent deregulation of cell cycle control induced by polycyclic aromatic hydrocarbons in rat liver epithelial cells.
Mutation research 2007;615(1-2):87-97.
2006: Viktor Horváth; Olga Blanárová; Lenka Švihálková-Šindlerová; Karel Soucek; Jirina Hofmanová; Petr Sova; Ales Kroutil; Peter Fedorocko; Alois Kozubík
Platinum(IV) complex with adamantylamine overcomes intrinsic resistance to cisplatin in ovarian cancer cells.
Gynecologic oncology 2006;102(1):32-40.
2006: Jan Vondrácek; Lenka Švihálková-Šindlerová; Katerina Pencíková; Pavel Krcmár; Zdenek Andrysík; Katerina Chramostová; Sona Marvanová; Zuzana Valovicová; Alois Kozubík; Alena Gábelová; Miroslav Machala
7H-Dibenzo[c,g]carbazole and 5,9-dimethyldibenzo[c,g]carbazole exert multiple toxic events contributing to tumor promotion in rat liver epithelial 'stem-like' cells.
Mutation research 2006;596(1-2):43-56.
2005: Alois Kozubík; Viktor Horváth; Lenka Švihálková-Šindlerová; Karel Soucek; Jirina Hofmanová; Petr Sova; Ales Kroutil; Frantisek Zák; Adolf Mistr; Jaroslav Turánek
High effectiveness of platinum(IV) complex with adamantylamine in overcoming resistance to cisplatin and suppressing proliferation of ovarian cancer cells in vitro.
Biochemical pharmacology 2005;69(3):373-83.
2004: Jaroslav Turánek; Andrea Kasná; Dana Záluská; Jirí Neca; Veronika Kvardová; Pavlína Knötigová; Viktor Horváth; Lenka Švihálková-Šindlerová; Alois Kozubík; Petr Sova; Ales Kroutil; Frantisek Zák; Adolf Mistr
New platinum(IV) complex with adamantylamine ligand as a promising anti-cancer drug: comparison of in vitro cytotoxic potential towards A2780/cisR cisplatin-resistant cell line within homologous series of platinum(IV) complexes.
Anti-cancer drugs 2004;15(5):537-43.
2004: Katerina Chramostová; Jan Vondrácek; Lenka Švihálková-Šindlerová; Borivoj Vojtesek; Alois Kozubík; Miroslav Machala
Polycyclic aromatic hydrocarbons modulate cell proliferation in rat hepatic epithelial stem-like WB-F344 cells.
Toxicology and applied pharmacology 2004;196(1):136-48.
2004: Frantisek Zák; Jaroslav Turánek; Ales Kroutil; Petr Sova; Adolf Mistr; Anna Poulová; Petr Mikolin; Zdirad Zák; Andrea Kasná; Dana Záluská; Jirí Neca; Lenka Švihálková-Šindlerová; Alois Kozubík
Platinum(IV) complex with adamantylamine as nonleaving amine group: synthesis, characterization, and in vitro antitumor activity against a panel of cisplatin-resistant cancer cell lines.
Journal of medicinal chemistry 2004;47(3):761-3.