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Pere Puigserver

Research Profile

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Acetylation

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Francisca Vazquez; Hans R Widlund; Bruce M Spiegelman; Kavita Bhalla; Helen Chim; Clary B Clish; Geoffrey D Girnun; Scott R Granter; Ji-Hong Lim; Kerry Pierce; Pere Puigserver
PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress.
Ji-Hong Lim; Mitsuhisa Tabata; Yang K Xiang; John E Dominy; Zachary Gerhart-Hines; Sungjin Kim; Yoonjin Lee; Pere Puigserver
Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex.
Jessica A Hall; Yoonjin Lee; John E Dominy; Pere Puigserver
The sirtuin family's role in aging and age-associated pathologies.

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2013: Francisca Vazquez; Hans R Widlund; Bruce M Spiegelman; Kavita Bhalla; Helen Chim; Clary B Clish; Geoffrey D Girnun; Scott R Granter; Ji-Hong Lim; Kerry Pierce; Pere Puigserver
PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress.
Cancer cell 2013;23(3):287-301.
2013: Ji-Hong Lim; Mitsuhisa Tabata; Yang K Xiang; John E Dominy; Zachary Gerhart-Hines; Sungjin Kim; Yoonjin Lee; Pere Puigserver
Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex.
The Journal of biological chemistry 2013;288(10):7117-26.
2013: Jessica A Hall; Yoonjin Lee; John E Dominy; Pere Puigserver
The sirtuin family's role in aging and age-associated pathologies.
The Journal of clinical investigation 2013;123(3):973-9.
2012: John E Dominy; Jessica Feldman; Steven P Gygi; Mark P Jedrychowski; Michael J Jurczak; Yoonjin Lee; Raul Mostoslavsky; Kerry Pierce; Joao Paulo Camporez; Helen Chim; Clary B Clish; John M Denu; Hai-Bin Ruan; Gerald I Shulman; Xiaoyong Yang; Pere Puigserver
The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.
Molecular cell 2012;48(6):900-13.
2012: Li Ye; Jun Wu; Alexander S Banks; Pontus Boström; David E Clapham; Paul Cohen; Patrick R Griffin; Rana K Gupta; Theodore M Kamenecka; Melin J Khandekar; Sandra Kleiner; Dina Laznik; Wolfgang Liedtke; Rina J Mepani; Vamsi K Mootha; Pere Puigserver; Rajan Sah; Xinyi Song; Bruce M Spiegelman
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.
Cell 2012;151(1):96-110.
2012: Arkaitz Carracedo; Vincent C J de Boer; Ainara Egia; Lydia S Finley; Zachary Gerhart-Hines; Marcia C Haigis; Keisuke Ito; Gaelle Laurent; Amy K Leliaert; Towia Libermann; Elefteria Maratos-Flier; Pere Puigserver; Andrea L Richardson; Zachary T Schafer; Su Jung Song; Maria Sundvall; Dror Weiss; Andrew C Adams; Manoj Bhasin; Pier P Pandolfi
A metabolic prosurvival role for PML in breast cancer.
The Journal of clinical investigation 2012;122(9):3088-100.
2012: Sharon M Blättler; Helen Chim; John T Cunningham; Marc Liesa; Huifei Liu; Klaas Romanino; Markus A Rüegg; Yang Shi; orian shirihai; Francisca Vazquez; Francisco Verdeguer; Rutger O Vogel; Pere Puigserver
Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle.
Molecular and cellular biology 2012;32(16):3333-46.
2012: Sharon M Blättler; Helen Chim; John T Cunningham; Steven P Gygi; Wilhelm Haas; Huifei Liu; Klaas Romanino; Markus A Rüegg; Yang Shi; Francisco Verdeguer; Pere Puigserver
Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling.
Cell metabolism 2012;15(4):505-17.
2012: John E Dominy; Francisca Vazquez; Pere Puigserver
Glycine decarboxylase cleaves a "malignant" metabolic path to promote tumor initiation.
Cancer cell 2012;21(2):143-5.
2011: Zachary Gerhart-Hines; Steven P Gygi; Alexander S Banks; Mark P Jedrychowski; Helen Chim; John E Dominy; Ji-Hong Lim; Sharon M Blättler; Pere Puigserver
The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).
Molecular cell 2011;44(6):851-63.
2011: Klaas Romanino; Agnès Conjard-Duplany; Francesco Zorzato; Verena Albert; C Florian Bentzinger; Yann-Gaël Gangloff; Pere Puigserver; Laetitia Mazelin; Shuo Lin; Christoph Handschin; Laurent Schaeffer; Markus A Rüegg
Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(51):20808-13.
2011: Kavita Bhalla; Laszlo Boros; Ruby E Dewi; Hongbin Fang; Bor-Jang Hwang; Lihui Ou; Pere Puigserver; William Twaddel; Scott B Vafai; Francesca Vazquez; Geoffrey D Girnun
PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis.
Cancer research 2011;71(21):6888-98.
2011: Timothy J Kelly; Clary B Clish; Amanda L Souza; Pere Puigserver
A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1alpha stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like.
Molecular and cellular biology 2011;31(13):2696-706.
2011: Joseph T Rodgers; Rutger O Vogel; Pere Puigserver
Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt.
Molecular cell 2011;41(4):471-9.
2011: J E Dominy; Zachary Gerhart-Hines; Pere Puigserver
Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming.
Cold Spring Harbor symposia on quantitative biology 2011;76():203-9.
2010: John E Dominy; Pere Puigserver
Nuclear FoxO1 inflames insulin resistance.
The EMBO journal 2010;29(24):4068-9.
2010: John E Dominy; Yoonjin Lee; Zachary Gerhart-Hines; Pere Puigserver
Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5.
Biochimica et biophysica acta 2010;1804(8):1676-83.
2010: Amy K Walker; Fajun Yang; Karen Jiang; Jun-Yuan Ji; Jennifer L Watts; Aparna Purushotham; Olivier Boss; Michael L Hirsch; Scott Ribich; Jesse J Smith; Kristine Israelian; Christoph H Westphal; Joseph T Rodgers; Toshi Shioda; Sarah L Elson; Peter Mulligan; Hani Najafi-Shoushtari; Josh C Black; Jitendra K Thakur; Lisa C Kadyk; Johnathan R Whetstine; Raul Mostoslavsky; Pere Puigserver; Xiaoling Li; Nicholas J Dyson; Anne C Hart; Anders M Näär
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.
Genes & development 2010;24(13):1403-17.
2010: Joseph T Rodgers; Wilhelm Haas; Steven P Gygi; Pere Puigserver
Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis.
Cell metabolism 2010;11(1):23-34.
2009: Zhiyong Cheng; Shaodong Guo; Kyle Copps; Xiaochen Dong; Ramya Kollipara; Joseph T Rodgers; Ronald A DePinho; Pere Puigserver; Morris F White
Foxo1 integrates insulin signaling with mitochondrial function in the liver.
Nature medicine 2009;15(11):1307-11.
2009: Zachary T Schafer; Alexandra R Grassian; Loling Song; Zhenyang Jiang; Zachary Gerhart-Hines; Hanna Yoko Irie; Sizhen Gao; Pere Puigserver; Joan S Brugge
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment.
Nature 2009;461(7260):109-13.
2009: Timothy J Kelly; Carles Lerin; Wilhelm Haas; Steven P Gygi; Pere Puigserver
GCN5-mediated transcriptional control of the metabolic coactivator PGC-1beta through lysine acetylation.
The Journal of biological chemistry 2009;284(30):19945-52.
2009: Carles Cantó; Zachary Gerhart-Hines; Jerome N Feige; Marie Lagouge; Lilia Noriega; Jill C Milne; Peter J Elliott; Pere Puigserver; Johan Auwerx
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity.
Nature 2009;458(7241):1056-60.
2009: Joseph T Rodgers; Pere Puigserver
Insulin resistance: beta-arrestin development.
Cell research 2009;19(3):275-6.
2009: Michael P Housley; Namrata D Udeshi; Joseph T Rodgers; Jeffrey Shabanowitz; Pere Puigserver; Donald F Hunt; Gerald W Hart
A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose.
The Journal of biological chemistry 2009;284(8):5148-57.
2009: Gabriela Suchankova; Lauren E Nelson; Zachary Gerhart-Hines; Meghan Kelly; Marie-Soleil Gauthier; Asish K Saha; Yasuo Ido; Pere Puigserver; Neil B Ruderman
Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells.
Biochemical and biophysical research communications 2009;378(4):836-41.
2008: Agnès Coste; Jean-Francois Louet; Marie Lagouge; Carles Lerin; Maria Cristina Antal; H Meziane; Kristina Schoonjans; Pere Puigserver; Bert W O'Malley; Johan Auwerx
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(44):17187-92.
2008: Michael P Housley; Joseph T Rodgers; Namrata D Udeshi; Timothy J Kelly; Jeffrey Shabanowitz; Donald F Hunt; Pere Puigserver; Gerald W Hart
O-GlcNAc regulates FoxO activation in response to glucose.
The Journal of biological chemistry 2008;283(24):16283-92.
2008: Joseph T Rodgers; Carles Lerin; Zachary Gerhart-Hines; Pere Puigserver
Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways.
FEBS letters 2008;582(1):46-53.
2007: John T Cunningham; Joseph T Rodgers; Daniel H Arlow; Francisca Vazquez; Vamsi K Mootha; Pere Puigserver
mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
Nature 2007;450(7170):736-40.
2007: Joseph T Rodgers; Pere Puigserver
Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(31):12861-6.
2007: Dohoon Kim; Minh Dang Nguyen; Matthew M Dobbin; Andre Fischer; Farahnaz Sananbenesi; Joseph T Rodgers; Ivana Delalle; Joseph A Baur; Guangchao Sui; Sean M Armour; Pere Puigserver; David A Sinclair; Li-Huei Tsai
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.
The EMBO journal 2007;26(13):3169-79.
2007: Zachary Gerhart-Hines; Joseph T Rodgers; Olivia Bare; Carles Lerin; Seung-Hee Kim; Raul Mostoslavsky; Frederick W Alt; Zhidan Wu; Pere Puigserver
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha.
The EMBO journal 2007;26(7):1913-23.
2007: Joseph T Rodgers; Pere Puigserver
Receptor feasts on sugar and cholesterol.
Nature medicine 2007;13(2):128-9.
2006: Marie Lagouge; Carmen Argmann; Zachary Gerhart-Hines; Hamid Meziane; Carles Lerin; Frédéric Daussin; Nadia Messadeq; Jill Milne; Philip Lambert; Peter Elliott; Bernard Geny; Markku Laakso; Pere Puigserver; Johan Auwerx
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
Cell 2006;127(6):1109-22.
2006: Joseph A Baur; Kevin J Pearson; Nathan L Price; Hamish A Jamieson; Carles Lerin; Avash Kalra; Vinayakumar V Prabhu; Joanne S Allard; Guillermo Lopez-LLuch; Kaitlyn Lewis; Paul J Pistell; Suresh Poosala; Kevin G Becker; Olivier Boss; Dana Gwinn; Mingyi Wang; Sharan Ramaswamy; Kenneth W Fishbein; RICHARD SPENCER; Edward G Lakatta; DAVID LE COUTEUR; Reuben J. Shaw; Plácido Navas; Pere Puigserver; Donald Ingram; Rafael de Cabo; David A Sinclair
Resveratrol improves health and survival of mice on a high-calorie diet.
Nature 2006;444(7117):337-42.
2006: Seung Hun Cha; Joseph T Rodgers; Pere Puigserver; Shigeru Chohnan; M Daniel Lane
Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(42):15410-5.
2006: Weiping Qin; Tianle Yang; Lap Ho; Rudy Zhao; Jun Wang; Linghong Chen; Wei Zhao; Meenakshisundaram Thiyagarajan; Donal MacGrogan; Joseph T Rodgers; Pere Puigserver; Junichi Sadoshima; Haiteng Deng; Steve Pedrini; Sam Gandy; Anthony A Sauve; Giulio Maria Pasinetti
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction.
The Journal of biological chemistry 2006;281(31):21745-54.
2006: Carles Lerin; Joseph T Rodgers; Dario E Kalume; Seung-hee Kim; Akhilesh Pandey; Pere Puigserver
GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha.
Cell metabolism 2006;3(6):429-38.
2006: Joseph T Rodgers; Pere Puigserver
Certainly can't live without this: SIRT6.
Cell metabolism 2006;3(2):77-8.
2006: Pere Puigserver; Joseph T Rodgers
Foxa2, a novel transcriptional regulator of insulin sensitivity.
Nature medicine 2006;12(1):38-9.
2005: Joseph T Rodgers; Carles Lerin; Wilhelm Haas; Steven P Gygi; Bruce M Spiegelman; Pere Puigserver
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.
Nature 2005;434(7029):113-8.
2005: Pere Puigserver
Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-alpha.
International journal of obesity (2005) 2005;29 Suppl 1():S5-9.
2004: Vamsi K Mootha; Christoph Handschin; Dan Arlow; Xiaohui Xie; Julie St Pierre; Smita Sihag; Wenli Yang; David Altshuler; Pere Puigserver; Nick Patterson; Patricia J Willy; Ira G Schulman; Richard A Heyman; Eric S Lander; Bruce M Spiegelman
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(17):6570-5.
2004: Wenhong Cao; Kiefer W Daniel; jacques robidoux; Pere Puigserver; Alexander Medvedev; Xu Bai; Lisa M Floering; Bruce M Spiegelman; Sheila Collins
p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene.
Molecular and cellular biology 2004;24(7):3057-67.
2004: Melina Fan; James Rhee; Julie St-Pierre; Christoph Handschin; Pere Puigserver; Jiandie Lin; Sibylle Jäeger; Hediye Erdjument-Bromage; Paul Tempst; Bruce M Spiegelman
Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK.
Genes & development 2004;18(3):278-89.
2003: Jiandie Lin; Paul T Tarr; Ruojing Yang; James Rhee; Pere Puigserver; Christopher B Newgard; Bruce M Spiegelman
PGC-1beta in the regulation of hepatic glucose and energy metabolism.
The Journal of biological chemistry 2003;278(33):30843-8.
2003: J Cliff Yoon; Gang Xu; Jude T Deeney; Shao-Nian Yang; James Rhee; Pere Puigserver; Adah R Levens; Ruojing Yang; Chen-Yu zhang; Bradford B Lowell; Per-Olof Berggren; Christopher B Newgard; Susan Bonner-Weir; Gordon Weir; Bruce M Spiegelman
Suppression of beta cell energy metabolism and insulin release by PGC-1alpha.
Developmental cell 2003;5(1):73-83.
2003: Vamsi K Mootha; Cecilia M Lindgren; Karl-Fredrik Eriksson; Aravind Subramanian; Smita Sihag; Joseph Lehar; Pere Puigserver; Emma Carlsson; Martin Ridderstråle; Esa Laurila; Nicholas Houstis; Mark J Daly; Nick Patterson; Jill P Mesirov; Todd R Golub; Pablo Tamayo; Bruce M Spiegelman; Eric S Lander; Joel N Hirschhorn; David Altshuler; Leif C Groop
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.
Nature genetics 2003;34(3):267-73.
2003: Pere Puigserver; James Rhee; Jerry Donovan; Christopher J Walkey; J Cliff Yoon; Francesco Oriente; Yukari Kitamura; Jennifer Altomonte; Hengjiang Dong; Domenico Accili; Bruce M Spiegelman
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.
Nature 2003;423(6939):550-5.
2003: James Rhee; Yusuke Inoue; J Cliff Yoon; Pere Puigserver; Melina Fan; Frank J Gonzalez; Bruce M Spiegelman
Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4012-7.
2003: Pere Puigserver; Bruce M Spiegelman
Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator.
Endocrine reviews 2003;24(1):78-90.
2003: Nicholas A Tritos; Jason W Mastaitis; Efi Kokkotou; Pere Puigserver; Bruce M Spiegelman; Eleftheria Maratos-Flier
Characterization of the peroxisome proliferator activated receptor coactivator 1 alpha (PGC 1alpha) expression in the murine brain.
Brain research 2003;961(2):255-60.
2002: Jiandie Lin; Hai Wu; Paul T Tarr; Chen-Yu zhang; Zhidan Wu; Olivier Boss; Laura F Michael; Pere Puigserver; Eiji Isotani; Eric N Olson; Bradford B Lowell; Rhonda Bassel-Duby; Bruce M Spiegelman
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres.
Nature 2002;418(6899):797-801.
2002: Jiandie Lin; Pere Puigserver; Jerry Donovan; Paul Tarr; Bruce M Spiegelman
Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor.
The Journal of biological chemistry 2002;277(3):1645-8.
2001: Pere Puigserver; James Rhee; Jiandie Lin; Zhidan Wu; J Cliff Yoon; Chen-Yu zhang; S Krauss; Vamsi K Mootha; Bradford B Lowell; Bruce M Spiegelman
Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1.
Molecular cell 2001;8(5):971-82.
2001: Stephan Herzig; Fanxin Long; Ulupi S Jhala; Susan Hedrick; R Quinn; anton bauer; D Rudolph; G Schutz; C Yoon; Pere Puigserver; Bruce M Spiegelman; Marc Montminy
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1.
Nature 2001;413(6852):179-83.
2001: J Cliff Yoon; Pere Puigserver; G Chen; J Donovan; Zhidan Wu; James Rhee; G Adelmant; J Stafford; C R Kahn; Daryl K Granner; Christopher B Newgard; Bruce M Spiegelman
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1.
Nature 2001;413(6852):131-8.
2001: L F Michael; Zhidan Wu; R B Cheatham; Pere Puigserver; G Adelmant; J J Lehman; D P Kelly; Bruce M Spiegelman
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3820-5.
2000: Bruce M Spiegelman; Pere Puigserver; Z Wu
Regulation of adipogenesis and energy balance by PPARgamma and PGC-1.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24 Suppl 4():S8-10.
2000: M Monsalve; Zhidan Wu; G Adelmant; Pere Puigserver; M Fan; Bruce M Spiegelman
Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1.
Molecular cell 2000;6(2):307-16.
2000: E D Rosen; C J Walkey; Pere Puigserver; Bruce M Spiegelman
Transcriptional regulation of adipogenesis.
Genes & development 2000;14(11):1293-307.
2000: Irina Tcherepanova; Pere Puigserver; John D Norris; Bruce M Spiegelman; Donald P McDonnell
Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1.
The Journal of biological chemistry 2000;275(21):16302-8.
1999: Z Wu; Pere Puigserver; Bruce M Spiegelman
Transcriptional activation of adipogenesis.
Current opinion in cell biology 1999;11(6):689-94.
1999: Pere Puigserver; G Adelmant; Zhidan Wu; M Fan; Jianming Xu; Bert W O'Malley; Bruce M Spiegelman
Activation of PPARgamma coactivator-1 through transcription factor docking.
Science (New York, N.Y.) 1999;286(5443):1368-71.
1999: Zhidan Wu; Pere Puigserver; Ulf Andersson; C Zhang; G Adelmant; Vamsi K Mootha; AE Troy; Saverio Cinti; Bradford B Lowell; R C Scarpulla; Bruce M Spiegelman
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1.
Cell 1999;98(1):115-24.
1999: Francisca Serra; M Luisa Bonet; Pere Puigserver; Jordi Oliver; Andreu Palou
Stimulation of uncoupling protein 1 expression in brown adipocytes by naturally occurring carotenoids.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23(6):650-5.
1998: Catalina Picó; Pere Puigserver; Paula Oliver; Andreu Palou
2-Methoxyestradiol, an endogenous metabolite of 17beta-estradiol, inhibits adipocyte proliferation.
Molecular and cellular biochemistry 1998;189(1-2):1-7.
1998: Pere Puigserver; Joan Ribot; Francisca Serra; Magdalena Gianotti; M Luisa Bonet; B Nadal-Ginard; Andreu Palou
Involvement of the retinoblastoma protein in brown and white adipocyte cell differentiation: functional and physical association with the adipogenic transcription factor C/EBPalpha.
European journal of cell biology 1998;77(2):117-23.
1998: Pere Puigserver; Zhidan Wu; C W Park; R Graves; Margaret E. Wright; Bruce M Spiegelman
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.
Cell 1998;92(6):829-39.
1997: F J Garcia-Palmer; J Pericas; J C Matamala; Pere Puigserver; M Luisa Bonet; Andreu Palou; Magdalena Gianotti
Diminished response to food deprivation of the rat brown adipose tissue mitochondrial uncoupling system with age.
Biochemistry and molecular biology international 1997;42(6):1151-61.
1997: M Luisa Bonet; Pere Puigserver; Francisca Serra; Joan Ribot; F Vázquez; C Pico; Andreu Palou
Retinoic acid modulates retinoid X receptor alpha and retinoic acid receptor alpha levels of cultured brown adipocytes.
FEBS letters 1997;406(1-2):196-200.
1996: Pere Puigserver; F Vázquez; M Luisa Bonet; Catalina Picó; Andreu Palou
In vitro and in vivo induction of brown adipocyte uncoupling protein (thermogenin) by retinoic acid.
The Biochemical journal 1996;317 ( Pt 3)():827-33.
1996: Pere Puigserver; Catalina Picó; M J Stock; Andreu Palou
Effect of selective beta-adrenoceptor stimulation on UCP synthesis in primary cultures of brown adipocytes.
Molecular and cellular endocrinology 1996;117(1):7-16.
1994: M Moreno; Pere Puigserver; J Llull; Magdalena Gianotti; Antonia Lanni; Fernando Goglia; Andreu Palou
Cold exposure induces different uncoupling-protein thermogenin masking/unmasking processes in brown adipose tissue depending on mitochondrial subtypes.
The Biochemical journal 1994;300 ( Pt 2)():463-8.
1992: Pere Puigserver; Andreu Palou; Magdalena Gianotti
Dietary regulation of fasting-induced mitochondrial protein degradation in adult rat brown adipose tissue.
Biochemistry international 1992;27(6):1037-46.
1992: Pere Puigserver; D Herron; Magdalena Gianotti; Andreu Palou; Barbara Cannon; Jan Nedergaard
Induction and degradation of the uncoupling protein thermogenin in brown adipocytes in vitro and in vivo. Evidence for a rapidly degradable pool.
The Biochemical journal 1992;284 ( Pt 2)():393-8.
1992: Pere Puigserver; Magdalena Gianotti; Andreu Palou
Impaired starvation-induced loss of mitochondrial protein in the brown adipose tissue of dietary obese rats.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1992;16(4):255-61.
1991: Pere Puigserver; Isabel Lladó; Andreu Palou; Magdalena Gianotti
Evidence for masking of brown adipose tissue mitochondrial GDP-binding sites in response to fasting in rats made obese by dietary manipulation. Effects of reversion to standard diet.
The Biochemical journal 1991;279 ( Pt 2)():575-9.