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Ralph Carvalho

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Alexander B Mohseny; Herman P Spaink; Wei Xiao; Ralph Carvalho; Pancras C W Hogendoorn; Anne-Marie Cleton-Jansen
An osteosarcoma zebrafish model implicates Mmp-19 and Ets-1 as well as reduced host immune response in angiogenesis and migration.
Ralph Carvalho; Jan de Sonneville; Oliver W Stockhammer; Nigel D L Savage; Wouter J Veneman; Tom H M Ottenhoff; Ron P Dirks; Annemarie H Meijer; Herman P Spaink
A high-throughput screen for tuberculosis progression.
Anya N A Milne; R Leguit; W E Corver; Folkert H Morsink; M Polak; Wendy W J De Leng; Ralph Carvalho; G Johan A Offerhaus
Loss of CDC4/FBXW7 in gastric carcinoma.

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2012: Alexander B Mohseny; Herman P Spaink; Wei Xiao; Ralph Carvalho; Pancras C W Hogendoorn; Anne-Marie Cleton-Jansen
An osteosarcoma zebrafish model implicates Mmp-19 and Ets-1 as well as reduced host immune response in angiogenesis and migration.
The Journal of pathology 2012;227(2):245-53.
2011: Ralph Carvalho; Jan de Sonneville; Oliver W Stockhammer; Nigel D L Savage; Wouter J Veneman; Tom H M Ottenhoff; Ron P Dirks; Annemarie H Meijer; Herman P Spaink
A high-throughput screen for tuberculosis progression.
PloS one 2011;6(2):e16779.
2010: Anya N A Milne; R Leguit; W E Corver; Folkert H Morsink; M Polak; Wendy W J De Leng; Ralph Carvalho; G Johan A Offerhaus
Loss of CDC4/FBXW7 in gastric carcinoma.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2010;32(5-6):347-59.
2009: Tihomir Todorov; Antoniya Todorova; Anders O H Nygren; Iliana Boneva; Ralph Carvalho; Boyan Dimitrov; Andrey Kirov; Vanio Mitev
Fragile X mosaic male full mutation/normal allele detected by PCR/MS-MLPA.
BMJ case reports 2009;2009():.
2008: Anders O H Nygren; Sylvia I Lens; Ralph Carvalho
Methylation-specific multiplex ligation-dependent probe amplification enables a rapid and reliable distinction between male FMR1 premutation and full-mutation alleles.
The Journal of molecular diagnostics : JMD 2008;10(6):496-501.
2008: W A van Hattem; Lodewijk A A Brosens; Wendy W J De Leng; F H Morsink; S Lens; Ralph Carvalho; Francis M Giardiello; G Johan A Offerhaus
Large genomic deletions of SMAD4, BMPR1A and PTEN in juvenile polyposis.
Gut 2008;57(5):623-7.
2008: Anya N A Milne; Ralph Carvalho; Marnix Jansen; E K Kranenbarg; C J H van de Velde; F M Morsink; Alex R Musler; Marian A J Weterman; G Johan A Offerhaus
Cyclin E low molecular weight isoforms occur commonly in early-onset gastric cancer and independently predict survival.
Journal of clinical pathology 2008;61(3):311-6.
2008: W Arnout van Hattem; Ralph Carvalho; Ang Li; G Johan A Offerhaus; Michael Goggins
Amplification of EMSY gene in a subset of sporadic pancreatic adenocarcinomas.
International journal of clinical and experimental pathology 2008;1(4):343-51.
2007: Wendy W J De Leng; Marnix Jansen; Ralph Carvalho; M Polak; Alex R Musler; Anya N A Milne; Josbert J Keller; Fred H Menko; Felix W M de Rooij; Christine A Iacobuzio-Donahue; Francis M Giardiello; Marian A J Weterman; G Johan A Offerhaus
Genetic defects underlying Peutz-Jeghers syndrome (PJS) and exclusion of the polarity-associated MARK/Par1 gene family as potential PJS candidates.
Clinical genetics 2007;72(6):568-73.
2007: Anya N A Milne; Robert Sitarz; Ralph Carvalho; Mirjam M Polak; M J L Ligtenberg; Patrick Pauwels; G Johan A Offerhaus; Marian A J Weterman
Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis.
Human pathology 2007;38(6):903-13.
2007: Anya N A Milne; Robert Sitarz; Ralph Carvalho; Fátima Carneiro; G Johan A Offerhaus
Early onset gastric cancer: on the road to unraveling gastric carcinogenesis.
Current molecular medicine 2007;7(1):15-28.
2006: Ralph Carvalho; Anya N A Milne; Mirjam Polak; G Johan A Offerhaus; Marian A J Weterman
A novel region of amplification at 11p12-13 in gastric cancer, revealed by representational difference analysis, is associated with overexpression of CD44v6, especially in early-onset gastric carcinomas.
Genes, chromosomes & cancer 2006;45(10):967-75.
2006: Anya N A Milne; Ralph Carvalho; Folkert M Morsink; Alex R Musler; Wendy W J De Leng; Ari Ristimäki; G Johan A Offerhaus
Early-onset gastric cancers have a different molecular expression profile than conventional gastric cancers.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006;19(4):564-72.
2005: Ralph Carvalho; Anya N A Milne; Mirjam Polak; Willem E Corver; G Johan A Offerhaus; Marian A J Weterman
Exclusion of RUNX3 as a tumour-suppressor gene in early-onset gastric carcinomas.
Oncogene 2005;24(56):8252-8.
2005: Lodewijk A A Brosens; Christine A Iacobuzio-Donahue; Josbert J Keller; Steven R Hustinx; Ralph Carvalho; Folkert H Morsink; Linda M Hylind; G Johan A Offerhaus; Francis M Giardiello; Michael Goggins
Increased cyclooxygenase-2 expression in duodenal compared with colonic tissues in familial adenomatous polyposis and relationship to the -765G -> C COX-2 polymorphism.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(11):4090-6.
2005: Noriyoshi Fukushima; Jens Koopmann; Norihiro Sato; Nijaguna B Prasad; Ralph Carvalho; Steven D Leach; Ralph Hruban; Michael Goggins
Gene expression alterations in the non-neoplastic parenchyma adjacent to infiltrating pancreatic ductal adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(6):779-87.
2004: Anya N A Milne; Ralph Carvalho; Bastiaan P van Rees; J J B van Lanschot; G Johan A Offerhaus; Marian A J Weterman
Do collision tumors of the gastroesophageal junction exist? A molecular analysis.
The American journal of surgical pathology 2004;28(11):1492-8.
2004: Ralph Carvalho; Anya N A Milne; Bastiaan P van Rees; Eric Caspers; Luís Cirnes; Ceu Figueiredo; G Johan A Offerhaus; Marian A J Weterman
Early-onset gastric carcinomas display molecular characteristics distinct from gastric carcinomas occurring at a later age.
The Journal of pathology 2004;204(1):75-83.
2003: José Carlos Machado; Ceu Figueiredo; Paulo Canedo; Paul Pharoah; Ralph Carvalho; Sérgio Nabais; Catarina Castro Alves; Maria Luisa Campos; Leen-Jan van Doorn; Carlos Caldas; Raquel Seruca; Fátima Carneiro; Manuel Sobrinho-Simões
A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma.
Gastroenterology 2003;125(2):364-71.
2002: Ceu Figueiredo; José Carlos Machado; Paul Pharoah; Raquel Seruca; Sónia Sousa; Ralph Carvalho; Ana Filipa Capelinha; Wim Quint; Carlos Caldas; Leen-Jan van Doorn; Fátima Carneiro; Manuel Sobrinho-Simões
Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma.
Journal of the National Cancer Institute 2002;94(22):1680-7.
2002: Ralph Carvalho; Tuncay Kayademir; Paula Soares; Paulo Canedo; Sónia Sousa; Carla Oliveira; Peter Leistenschneider; Raquel Seruca; Peter Gött; nikolaus blin; Fátima Carneiro; José Carlos Machado
Loss of heterozygosity and promoter methylation, but not mutation, may underlie loss of TFF1 in gastric carcinoma.
Laboratory investigation; a journal of technical methods and pathology 2002;82(10):1319-26.
2001: José Carlos Machado; Paul Pharoah; Sónia Sousa; Ralph Carvalho; Carla Oliveira; Ceu Figueiredo; António Amorim; Raquel Seruca; Carlos Caldas; Fátima Carneiro; Manuel Sobrinho-Simões
Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma.
Gastroenterology 2001;121(4):823-9.
2001: José Carlos Machado; Carla Oliveira; Ralph Carvalho; Paula Soares; G Berx; Carlos Caldas; Raquel Seruca; Fátima Carneiro; M Sobrinho-Simöes
E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma.
Oncogene 2001;20(12):1525-8.