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Zhou Zhu

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Yu Sam Kim; Y-Y Koh; W-H Lee; J Park; T-Y Roh; Zhou Zhu; E-J Choi; S-J Choi; Yong Song Gho; Y-K Jee; Yoon-Keun Kim
Extracellular vesicles, especially derived from Gram-negative bacteria, in indoor dust induce neutrophilic pulmonary inflammation associated with both Th1 and Th17 cell responses.
Li Zhou; Yuqi Zhou; Min Hee Oh; Sun-Young Oh; Clifford M Takemoto; Nico van Rooijen; Yefu Wang; Fan Wu; Baojun Yuan; Tao Zheng; Zhou Zhu
SHP-1 regulation of mast cell function in allergic inflammation and anaphylaxis.
Ying Wang; Jo Rae Wright; Zhou Zhu; Njira L Lugogo; Loretta G Que; Denise M Beaver; Tony D Church; Dave Francisco; Molly Huggins; Jennifer L Ingram; Monica Kraft
SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells.

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2013: Yu Sam Kim; Y-Y Koh; W-H Lee; J Park; T-Y Roh; Zhou Zhu; E-J Choi; S-J Choi; Yong Song Gho; Y-K Jee; Yoon-Keun Kim
Extracellular vesicles, especially derived from Gram-negative bacteria, in indoor dust induce neutrophilic pulmonary inflammation associated with both Th1 and Th17 cell responses.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2013;43(4):443-54.
2013: Li Zhou; Yuqi Zhou; Min Hee Oh; Sun-Young Oh; Clifford M Takemoto; Nico van Rooijen; Yefu Wang; Fan Wu; Baojun Yuan; Tao Zheng; Zhou Zhu
SHP-1 regulation of mast cell function in allergic inflammation and anaphylaxis.
PloS one 2013;8(2):e55763.
2012: Ying Wang; Jo Rae Wright; Zhou Zhu; Njira L Lugogo; Loretta G Que; Denise M Beaver; Tony D Church; Dave Francisco; Molly Huggins; Jennifer L Ingram; Monica Kraft
SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(7):3371-81.
2012: Meryem Aloulou; Sanae Ben Mkaddem; Marc Benhamou; Martine Biarnes-Pelicot; Ulrich Blank; Tarek Boussetta; Bruno Crestani; Pierre Launay; Elisabetta Rossato; Hervé Souchet; Zhou Zhu; Renato C Monteiro
IgG1 and IVIg induce inhibitory ITAM signaling through FcγRIII controlling inflammatory responses.
Blood 2012;119(13):3084-96.
2012: Jinho Yu; Zhou Zhu; Chen Dong; Allen C Myers; Min Hee Oh; Ju-Un Park; Tao Zheng
Epicutaneous exposure to staphylococcal superantigen enterotoxin B enhances allergic lung inflammation via an IL-17A dependent mechanism.
PloS one 2012;7(7):e39032.
2012: Seok Hyun Cho; Joan Lee; Sun-Young Oh; Zhou Zhu; Andrew Lane
Spontaneous eosinophilic nasal inflammation in a genetically-mutant mouse: comparative study with an allergic inflammation model.
PloS one 2012;7(4):e35114.
2011: An Chen; Beixue Gao; Sang-Myeong Lee; Stephen Shannon; Zhou Zhu; Deyu Fang
c-Abl-mediated tyrosine phosphorylation of the T-bet DNA-binding domain regulates CD4+ T-cell differentiation and allergic lung inflammation.
Molecular and cellular biology 2011;31(16):3445-56.
2011: MIN-HEE OH; Sun-Young Oh; Jinho Yu; Warren J Leonard; Yong Jun Liu; Allen C Myers; Zhou Zhu; Tao Zheng
IL-13 induces skin fibrosis in atopic dermatitis by thymic stromal lymphopoietin.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(12):7232-42.
2011: Byung-Jae Lee; Hyung-Geun Moon; Tae-Seop Shin; Seong Gyu Jeon; Eun-Young Lee; Yong Song Gho; Chun Geun Lee; Zhou Zhu; Jack A Elias; Yoon-Keun Kim
Protective effects of basic fibroblast growth factor in the development of emphysema induced by interferon-γ.
Experimental & molecular medicine 2011;43(4):169-78.
2011: Tao Zheng; Jinho Yu; MIN-HEE OH; Zhou Zhu
The atopic march: progression from atopic dermatitis to allergic rhinitis and asthma.
Allergy, asthma & immunology research 2011;3(2):67-73.
2011: Sun-Young Oh; J-U Park; Tao Zheng; Yoon-Keun Kim; F Wu; S H Cho; D Barber; Josef M Penninger; Zhou Zhu
Cbl-b regulates airway mucosal tolerance to aeroallergen.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2011;41(3):434-42.
2011: Jin P Guo; Mary E Brummet; Allen C Myers; Ho Jeong Na; Elizabeth Rowland; Ronald Schnaar; Tao Zheng; Zhou Zhu; Bruce S Bochner
Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs.
American journal of respiratory cell and molecular biology 2011;44(2):238-43.
2011: Zhou Zhu; Yong Jun Liu; Min-Hee Oh; Jinho Yu; Tao Zheng
The Role of TSLP in IL-13-induced atopic march.
Scientific reports 2011;1():23.
2010: You-Sun Kim; Seng-Jin Choi; You-Me Tae; Byung-Jae Lee; Seong Gyu Jeon; Sun-Young Oh; Yong Song Gho; Zhou Zhu; Yoon-Keun Kim
Distinct roles of vascular endothelial growth factor receptor-1- and receptor-2-mediated signaling in T cell priming and Th17 polarization to lipopolysaccharide-containing allergens in the lung.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):5648-55.
2010: J-P Choi; Yu Sam Kim; Y-M Tae; E-J Choi; B-S Hong; Seong Gyu Jeon; Yong Song Gho; Zhou Zhu; Yoon-Keun Kim
A viral PAMP double-stranded RNA induces allergen-specific Th17 cell response in the airways which is dependent on VEGF and IL-6.
Allergy 2010;65(10):1322-30.
2010: T-S Shin; Jong-Hoon Kim; Yu Sam Kim; Seong Gyu Jeon; Zhou Zhu; Yong Song Gho; Yoon-Keun Kim
Extracellular vesicles are key intercellular mediators in the development of immune dysfunction to allergens in the airways.
Allergy 2010;65(10):1256-65.
2010: H-G Moon; Y-M Tae; Y-S Kim; S Gyu Jeon; Sun-Young Oh; Y Song Gho; Zhou Zhu; Yoon-Keun Kim
Conversion of Th17-type into Th2-type inflammation by acetyl salicylic acid via the adenosine and uric acid pathway in the lung.
Allergy 2010;65(9):1093-103.
2010: You-Sun Kim; Seng-Jin Choi; Jun-Pyo Choi; Seong Gyu Jeon; Sun-Young Oh; Byung-Jae Lee; Yong Song Gho; Chun Geun Lee; Zhou Zhu; Jack A Elias; Yoon-Keun Kim
IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model.
Experimental & molecular medicine 2010;42(8):533-46.
2010: Zhou Zhu; Sun-Young Oh; You Sook Cho; Li Zhang; Yoon-Keun Kim; Tao Zheng
Tyrosine phosphatase SHP-1 in allergic and anaphylactic inflammation.
Immunologic research 2010;47(1-3):3-13.
2010: Zhou Zhu; Sun-Young Oh; Tao Zheng; Y-K Kim
Immunomodulating effects of endotoxin in mouse models of allergic asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010;40(4):536-46.
2010: Min Kyoung Jang; Sae-Hoon Kim; Ki-Young Lee; Tae-Bum Kim; Keun Ae Moon; Chan Sun Park; Yun Jeong Bae; Zhou Zhu; Hee-Bom Moon; You Sook Cho
The tyrosine phosphatase, SHP-1, is involved in bronchial mucin production during oxidative stress.
Biochemical and biophysical research communications 2010;393(1):137-43.
2010: Li Zhang; Sun-Young Oh; Xinxing Wu; MIN-HEE OH; Fan Wu; John T Schroeder; Clifford M Takemoto; Tao Zheng; Zhou Zhu
SHP-1 deficient mast cells are hyperresponsive to stimulation and critical in initiating allergic inflammation in the lung.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(3):1180-90.
2010: Sukit Roongapinun; Sun-Young Oh; Fan Wu; Ampai Panthong; Tao Zheng; Zhou Zhu
Role of SHIP-1 in the adaptive immune responses to aeroallergen in the airway.
PloS one 2010;5(11):e14174.
2010: Yueh-Chiao Yeh; Liping Xie; Jacqueline M Langdon; Allen C Myers; Sun-Young Oh; Zhou Zhu; Susan M MacDonald
The effects of overexpression of histamine releasing factor (HRF) in a transgenic mouse model.
PloS one 2010;5(6):e11077.
2009: You-Sun Kim; Sung-Wook Hong; Jun-Pyo Choi; Tae-Seop Shin; Hyung-Geun Moon; Eun-Jung Choi; Seong Gyu Jeon; Sun-Young Oh; Yong Song Gho; Zhou Zhu; Yoon-Keun Kim
Vascular endothelial growth factor is a key mediator in the development of T cell priming and its polarization to type 1 and type 17 T helper cells in the airways.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(8):5113-20.
2009: Qing Yu; Archna Sharma; Sun-Young Oh; Hyung-Geun Moon; M Zulfiquer Hossain; Theresa M Salay; Karen E Leeds; Hansen Du; Beibei Wu; Marian L Waterman; Zhou Zhu; Jyoti Misra Sen
T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma.
Nature immunology 2009;10(9):992-9.
2009: Seong Gyu Jeon; H-G Moon; Y-S Kim; J-P Choi; T-S Shin; Sun Woo Hong; Y-M Tae; S-H Kim; Zhou Zhu; Yong Song Gho; Yoon-Keun Kim
15-lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(6):908-17.
2009: Sun-Young Oh; Tao Zheng; Yoon-Keun Kim; Lauren Cohn; Robert J Homer; Andrew N J McKenzie; Zhou Zhu
A critical role of SHP-1 in regulation of type 2 inflammation in the lung.
American journal of respiratory cell and molecular biology 2009;40(5):568-74.
2009: Tao Zheng; MIN-HEE OH; Sun-Young Oh; John T Schroeder; Adam B Glick; Zhou Zhu
Transgenic expression of interleukin-13 in the skin induces a pruritic dermatitis and skin remodeling.
The Journal of investigative dermatology 2009;129(3):742-51.
2008: You Sook Cho; Sun-Young Oh; Zhou Zhu
Tyrosine phosphatase SHP-1 in oxidative stress and development of allergic airway inflammation.
American journal of respiratory cell and molecular biology 2008;39(4):412-9.
2008: Xuexian O Yang; Seon Hee Chang; Heon Park; Roza I Nurieva; Bhavin Shah; Luis Acero; Yi-Hong Wang; Kimberly Schluns; Russell R Broaddus; Zhou Zhu; Chen Dong
Regulation of inflammatory responses by IL-17F.
The Journal of experimental medicine 2008;205(5):1063-75.
2008: Tao Zheng; Wei Liu; Sun-Young Oh; Zhou Zhu; Buqu Hu; Robert J Homer; Lauren Cohn; Michael J Grusby; Jack A Elias
IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):522-9.
2007: Seong Gyu Jeon; Sun-Young Oh; Hye-Kyung Park; You-Sun Kim; Eun-Jin Shim; Hyun-Seung Lee; MIN-HEE OH; Boram Bang; Eun-Young Chun; Sang-Heon Kim; Yong Song Gho; Zhou Zhu; You-Young Kim; Yoon-Keun Kim
TH2 and TH1 lung inflammation induced by airway allergen sensitization with low and high doses of double-stranded RNA.
The Journal of allergy and clinical immunology 2007;120(4):803-12.
2007: Pornpimon Angkasekwinai; Heon Park; Yui-Hsi Wang; Yi-Hong Wang; Seon Hee Chang; David B Corry; Yong-Jun Liu; Zhou Zhu; Chen Dong
Interleukin 25 promotes the initiation of proallergic type 2 responses.
The Journal of experimental medicine 2007;204(7):1509-17.
2007: Yoon-Keun Kim; Sun-Young Oh; Seong Gyu Jeon; Heung-Woo Park; Soo-Yeon Lee; Eun-Young Chun; Boram Bang; Hyun-Seung Lee; MIN-HEE OH; You-Sun Kim; Jong-Hoon Kim; Yong Song Gho; Sang-Heon Cho; Kyung-Up Min; You-Young Kim; Zhou Zhu
Airway exposure levels of lipopolysaccharide determine type 1 versus type 2 experimental asthma.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):5375-82.
2007: Sun-Young Oh; Tao Zheng; Monica L Bailey; Dwayne Barber; John T Schroeder; Yoon-Keun Kim; Zhou Zhu
Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.
The Journal of allergy and clinical immunology 2007;119(1):123-31.
2006: Weisong Zhou; Koichi Hashimoto; Martin L Moore; Jack A Elias; Zhou Zhu; Joan Durbin; Giuseppe N Colasurdo; John A Rutigliano; Constance L Chiappetta; Kasia Goleniewska; Jamye F O'Neal; Barney S Graham; R Stokes Peebles
IL-13 is associated with reduced illness and replication in primary respiratory syncytial virus infection in the mouse.
Microbes and infection / Institut Pasteur 2006;8(14-15):2880-9.
2006: Vineet Bhandari; Rayman Choo-Wing; Chun Geun Lee; Zhou Zhu; Jonathan H Nedrelow; Geoffrey L Chupp; Xucher Zhang; Michael A Matthay; Lorraine B Ware; Robert J Homer; Patty J Lee; Anke Geick; Antonin R de Fougerolles; Jack A Elias
Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death.
Nature medicine 2006;12(11):1286-93.
2006: Robert J Homer; Zhou Zhu; Lauren Cohn; Chun Gun Lee; Wendy I White; Suping Chen; Jack A Elias
Differential expression of chitinases identify subsets of murine airway epithelial cells in allergic inflammation.
American journal of physiology. Lung cellular and molecular physiology 2006;291(3):L502-11.
2006: Yun M Shim; Zhou Zhu; Tao Zheng; Chun G Lee; Robert J Homer; Bing Ma; Jack A Elias
Role of 5-lipoxygenase in IL-13-induced pulmonary inflammation and remodeling.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1918-24.
2006: Patty J Lee; Xuchen Zhang; Peiying Shan; Bing Ma; Chun Geun Lee; Robert J Homer; Zhou Zhu; Mercedes Rincon; Brooke T Mossman; Jack A Elias
ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo.
The Journal of clinical investigation 2006;116(1):163-73.
2005: Heon Park; Zhaoxia Li; Xuexian O Yang; Seon Hee Chang; Roza I Nurieva; Yi-Hong Wang; Ying Wang; Leroy Hood; Zhou Zhu; Qiang Tian; Chen Dong
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17.
Nature immunology 2005;6(11):1133-41.
2005: Yuka Mizue; S Ghani; Lin Leng; Courtney McDonald; P Kong; John A Baugh; S J Lane; Joe Craft; Jun Nishihira; Seamas C Donnelly; Zhou Zhu; Richard Bucala
Role for macrophage migration inhibitory factor in asthma.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(40):14410-5.
2005: Tao Zheng; Morgan Rabach; ningyuan chen; Lesley A Rabach; Xiaoxia Hu; Jack A Elias; Zhou Zhu
Molecular cloning and functional characterization of mouse chitotriosidase.
Gene 2005;357(1):37-46.
2005: Tao Zheng; Zhou Zhu
Lessons from murine models of atopic dermatitis.
Current allergy and asthma reports 2005;5(4):291-7.
2005: Tao Zheng; Min Jong Kang; Kristina Crothers; Zhou Zhu; Wei Liu; Chun Geun Lee; Lesley A Rabach; Harold A Chapman; Robert J Homer; David Aldous; George T De Sanctis; George Desanctis; Stephen Underwood; Michael Graupe; Richard A Flavell; John A Schmidt; Jack A Elias
Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):8106-15.
2005: Chuan Hua He; Aaron B Waxman; Chun Geun Lee; Holger W Link; Morgan E Rabach; Bing Ma; Qingsheng Chen; Zhou Zhu; Mei Zhong; Keiko Nakayama; Keiichi I Nakayama; Robert J Homer; Jack A Elias
Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury.
The Journal of clinical investigation 2005;115(4):1039-48.
2004: Dianhua Jiang; Jiurong Liang; Jennifer Hodge; Bao Lu; Zhou Zhu; Shuang Yu; Juan Fan; Yunfei Gao; Zhinan Yin; Robert J Homer; Craig Gerard; Paul W Noble
Regulation of pulmonary fibrosis by chemokine receptor CXCR3.
The Journal of clinical investigation 2004;114(2):291-9.
2004: Zhou Zhu; Tao Zheng; Robert J Homer; Yoon-Keun Kim; ningyuan chen; Lauren Cohn; Qutayba Hamid; Jack A Elias
Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation.
Science (New York, N.Y.) 2004;304(5677):1678-82.
2004: Bing Ma; Zhou Zhu; Robert J Homer; Craig Gerard; Robert M Strieter; Jack A Elias
The C10/CCL6 chemokine and CCR1 play critical roles in the pathogenesis of IL-13-induced inflammation and remodeling.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1872-81.
2003: Jingming Wang; Qingsheng Chen; Jonathan Corne; Zhou Zhu; Chun Geun Lee; Vineet Bhandari; Robert J Homer; Jack A Elias
Pulmonary expression of leukemia inhibitory factor induces B cell hyperplasia and confers protection in hyperoxia.
The Journal of biological chemistry 2003;278(33):31226-32.
2003: Janci Chunn Lindsay; Chun Geun Lee; Hays W J Young; Zhou Zhu; Janci L Chunn; Min Jong Kang; Suman K Banerjee; Jack A Elias
Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway.
The Journal of clinical investigation 2003;112(3):332-44.
2003: Tao Zheng; Zhou Zhu; Wei Liu; Chun Geun Lee; Qingsheng Chen; Robert J Homer; Jack A Elias
Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro.
The Journal of allergy and clinical immunology 2003;111(4):720-8.
2003: Jack A Elias; Chun Geun Lee; Tao Zheng; Yun Shim; Zhou Zhu
Interleukin-13 and leukotrienes: an intersection of pathogenetic schema.
American journal of respiratory cell and molecular biology 2003;28(4):401-4.
2003: Zhou Zhu; Goran Enhorning; Tao Zheng; Qingsheng Chen; ningyuan chen; Robert J Homer; Jack A Elias
Interleukin-13 induces surfactant function abnormality in the murine lung.
Chest 2003;123(3 Suppl):375S-6S.
2003: Jack A Elias; Tao Zheng; Chun Geun Lee; Robert J Homer; Qingsheng Chen; Bing Ma; Michael Blackburn; Zhou Zhu
Transgenic modeling of interleukin-13 in the lung.
Chest 2003;123(3 Suppl):339S-45S.
2003: Jack A Elias; Chun Geun Lee; Tao Zheng; Bing Ma; Robert J Homer; Zhou Zhu
New insights into the pathogenesis of asthma.
The Journal of clinical investigation 2003;111(3):291-7.
2002: Sophie Lanone; Tao Zheng; Zhou Zhu; Wei Liu; Chun Geun Lee; Bing Ma; Qingsheng Chen; Robert J Homer; Jingming Wang; Lesley A Rabach; Morgan E Rabach; J Michael Shipley; Steven D Shapiro; Robert M Senior; Jack A Elias
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling.
The Journal of clinical investigation 2002;110(4):463-74.
2002: Douglas Kuperman; Xiaozhu Huang; Laura L Koth; Grace H Chang; Gregory M Dolganov; Zhou Zhu; Jack A Elias; Dean Sheppard; David J Erle
Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma.
Nature medicine 2002;8(8):885-9.
2002: Robert J Homer; Tao Zheng; Geoffrey L Chupp; Susan He; Zhou Zhu; Quingshen Chen; Bing Ma; R Duncan Hite; Laurice I Gobran; Seamus A Rooney; Jack A Elias
Pulmonary type II cell hypertrophy and pulmonary lipoproteinosis are features of chronic IL-13 exposure.
American journal of physiology. Lung cellular and molecular physiology 2002;283(1):L52-9.
2002: Zhou Zhu; Tao Zheng; Chun Geun Lee; Robert J Homer; Jack A Elias
Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling.
Seminars in cell & developmental biology 2002;13(2):121-8.
2002: Zhou Zhu; Bing Ma; Tao Zheng; Robert J Homer; Chun Geun Lee; Israel F Charo; Paul Noble; Jack A Elias
IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(6):2953-62.
2001: Zhou Zhu; Chun Geun Lee; Tao Zheng; Geoffrey L Chupp; Jingming Wang; Robert J Homer; Paul W Noble; Qutayba Hamid; Jack A Elias
Airway inflammation and remodeling in asthma. Lessons from interleukin 11 and interleukin 13 transgenic mice.
American journal of respiratory and critical care medicine 2001;164(10 Pt 2):S67-70.
2001: Jerry S Hu; Kirsten A Frait; F Reich; Zhou Zhu; J A Elias; Stephen W Chensue
IL-13 transgene state impairs mycobacterial (type-1) and schistosomal (type-2) antigen-elicited responses.
Cellular immunology 2001;213(2):114-21.
2001: Tao Zheng; Zhou Zhu; Jingming Wang; Robert J Homer; Jack A Elias
IL-11: insights in asthma from overexpression transgenic modeling.
The Journal of allergy and clinical immunology 2001;108(4):489-96.
2001: Chun Geun Lee; Robert J Homer; Zhou Zhu; Sophie Lanone; X Wang; V Koteliansky; J Michael Shipley; Philip J Gotwals; Paul Noble; Quingshen Chen; Robert M Senior; Jack A Elias
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).
The Journal of experimental medicine 2001;194(6):809-21.
2001: Zhou Zhu; Bing Ma; Robert J Homer; Tao Zheng; Jack A Elias
Use of the tetracycline-controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice.
The Journal of biological chemistry 2001;276(27):25222-9.
2000: Z Wang; Tao Zheng; Zhou Zhu; Robert J Homer; Richard J Riese; Harold A Chapman; Steven D Shapiro; Jack A Elias
Interferon gamma induction of pulmonary emphysema in the adult murine lung.
The Journal of experimental medicine 2000;192(11):1587-600.
2000: Tao Zheng; Zhou Zhu; Z Wang; Robert J Homer; Bing Ma; Richard J Riese; Harold A Chapman; Steven D Shapiro; Jack A Elias
Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema.
The Journal of clinical investigation 2000;106(9):1081-93.
2000: Chun Geun Lee; Ho Joo Yoon; Zhou Zhu; Holger W Link; Z Wang; JM Gwaltney; M Landry; Jack A Elias
Respiratory syncytial virus stimulation of vascular endothelial cell growth Factor/Vascular permeability factor.
American journal of respiratory cell and molecular biology 2000;23(5):662-9.
2000: J Corne; Geoffrey L Chupp; Chun Geun Lee; Robert J Homer; Zhou Zhu; Quingshen Chen; Bing Ma; Y Du; F Roux; J McArdle; Aaron B Waxman; Jack A Elias
IL-13 stimulates vascular endothelial cell growth factor and protects against hyperoxic acute lung injury.
The Journal of clinical investigation 2000;106(6):783-91.
2000: C Kuhn; R J Homer; Zhou Zhu; N Ward; J A Elias
Morphometry explains variation in airway responsiveness in transgenic mice overexpressing interleukin-6 and interleukin-11 in the lung.
Chest 2000;117(5 Suppl 1):260S-2S.
2000: C Kuhn; R J Homer; Zhou Zhu; N Ward; R A Flavell; Gregory P Geba; J A Elias
Airway hyperresponsiveness and airway obstruction in transgenic mice. Morphologic correlates in mice overexpressing interleukin (IL)-11 and IL-6 in the lung.
American journal of respiratory cell and molecular biology 2000;22(3):289-95.
2000: EM Minshall; Jamila Chakir; Michel Laviolette; Sophie Molet; Zhou Zhu; Ron Olivenstein; J A Elias; Qutayba Hamid
IL-11 expression is increased in severe asthma: association with epithelial cells and eosinophils.
The Journal of allergy and clinical immunology 2000;105(2 Pt 1):232-8.
1999: Jack A Elias; Zhou Zhu; Geoffrey L Chupp; Robert J Homer
Airway remodeling in asthma.
The Journal of clinical investigation 1999;104(8):1001-6.
1999: Ho Joo Yoon; Zhou Zhu; JM Gwaltney; Jack A Elias
Rhinovirus regulation of IL-1 receptor antagonist in vivo and in vitro: a potential mechanism of symptom resolution.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7461-9.
1999: Zhou Zhu; Robert J Homer; Z Wang; Quingshen Chen; Gregory P Geba; Jingming Wang; Y Zhang; Jack A Elias
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production.
The Journal of clinical investigation 1999;103(6):779-88.
1999: Jingming Wang; Zhou Zhu; R Nolfo; Jack A Elias
Dexamethasone regulation of lung epithelial cell and fibroblast interleukin-11 production.
The American journal of physiology 1999;276(1 Pt 1):L175-85.
1997: Zhou Zhu; W Tang; JM Gwaltney; Y Wu; Jack A Elias
Rhinovirus stimulation of interleukin-8 in vivo and in vitro: role of NF-kappaB.
The American journal of physiology 1997;273(4 Pt 1):L814-24.
1996: O Einarsson; Gregory P Geba; Zhou Zhu; M Landry; Jack A Elias
Interleukin-11: stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness.
The Journal of clinical investigation 1996;97(4):915-24.
1996: Zhou Zhu; W Tang; Anuradha Ray; Y Wu; O Einarsson; Marie L Landry; J Gwaltney; Jack A Elias
Rhinovirus stimulation of interleukin-6 in vivo and in vitro. Evidence for nuclear factor kappa B-dependent transcriptional activation.
The Journal of clinical investigation 1996;97(2):421-30.
1995: O Einarsson; Gregory P Geba; J R Panuska; Zhou Zhu; M Landry; Jack A Elias
Asthma-associated viruses specifically induce lung stromal cells to produce interleukin-11, a mediator of airways hyperreactivity.
Chest 1995;107(3 Suppl):132S-133S.