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Marc Buyse

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Sara A Hurvitz; John Mackey; Omkar Marathe; Miguel Martin; Tadeusz Pienkowski; Emmanuel Quinaux; Nicholas J Robert; Somasekar Seshagiri; Dennis J Slamon; Mark X Sliwkowski; Howard M Stern; Jeremy Stinson; Valerie Bee; David J Betting; Adam Brufsky; Marc Buyse; John Crown; Sambasivarao Damaraju; Adrian Driga; Wolfgang Eiermann; Carla Falkson; Vicente Valero; Ying Zhao; John M Timmerman
Analysis of Fcγ receptor IIIa and IIa polymorphisms: lack of correlation with outcome in trastuzumab-treated breast cancer patients.
Stuart G Baker; Marc Buyse; Daniel J Sargent; Tomasz Burzykowski
Predicting treatment effect from surrogate endpoints and historical trials: an extrapolation involving probabilities of a binary outcome or survival to a specific time.
Daniel J Sargent; Marc Buyse; Aimery de Gramont; Richard M Goldberg; Alastair Matheson
The ARCAD clinical trials program: an update and invitation.

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2012: Sara A Hurvitz; John Mackey; Omkar Marathe; Miguel Martin; Tadeusz Pienkowski; Emmanuel Quinaux; Nicholas J Robert; Somasekar Seshagiri; Dennis J Slamon; Mark X Sliwkowski; Howard M Stern; Jeremy Stinson; Valerie Bee; David J Betting; Adam Brufsky; Marc Buyse; John Crown; Sambasivarao Damaraju; Adrian Driga; Wolfgang Eiermann; Carla Falkson; Vicente Valero; Ying Zhao; John M Timmerman
Analysis of Fcγ receptor IIIa and IIa polymorphisms: lack of correlation with outcome in trastuzumab-treated breast cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(12):3478-86.
2012: Stuart G Baker; Marc Buyse; Daniel J Sargent; Tomasz Burzykowski
Predicting treatment effect from surrogate endpoints and historical trials: an extrapolation involving probabilities of a binary outcome or survival to a specific time.
Biometrics 2012;68(1):248-57.
2012: Daniel J Sargent; Marc Buyse; Aimery de Gramont; Richard M Goldberg; Alastair Matheson
The ARCAD clinical trials program: an update and invitation.
The oncologist 2012;17(2):188-91.
2011: Benoist Chibaudel; Carmen J Allegra; Franck bonnetain; Marc Buyse; Richard M Goldberg; Daniel J Sargent; Qian Shi; Christophe Tournigand; Aimery de Gramont
Alternative end points to evaluate a therapeutic strategy in advanced colorectal cancer: evaluation of progression-free survival, duration of disease control, and time to failure of strategy--an Aide et Recherche en Cancerologie Digestive Group Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(31):4199-204.
2011: Dennis J Slamon; Isabelle Tabah-Fisch; Vicente Valero; Frances Visco; Gunter von Minckwitz; Valerie Bee; Belguendouz Bendahmane; Marc Buyse; Arlene Chan; John Crown; Wolfgang Eiermann; John Glaspy; Mary-Ann Lindsay; Mei-Ching Liu; John Mackey; Miguel Martin; Marek Pawlicki; Tadeusz Pienkowski; Tamas Pinter; Michael Press; Alessandro Riva; Nicholas Robert; Guido Sauter
Adjuvant trastuzumab in HER2-positive breast cancer.
The New England journal of medicine 2011;365(14):1273-83.
2011: Marc Buyse; Sylvie Castaigne; Kristoffer Hellstrand; Kathryn J Lucchesi; Stefan Michiels; Mats L Brune; Pierre Squifflet; Jacob M Rowe
Leukemia-free survival as a surrogate end point for overall survival in the evaluation of maintenance therapy for patients with acute myeloid leukemia in complete remission.
Haematologica 2011;96(8):1106-12.
2011: Marc Buyse; Sylvie Castaigne; Sylvie Chevret; Stephen L George; Jonathan E Kolitz; Beverly J Lange; Richard A Larson; Kathryn J Lucchesi; Dominique Maraninchi; Pierre Squifflet; Todd A Alonzo; Didier Blaise; Clara D Bloomfield; Tomasz Burzykowski
Individual patient data meta-analysis of randomized trials evaluating IL-2 monotherapy as remission maintenance therapy in acute myeloid leukemia.
Blood 2011;117(26):7007-13.
2011: Daniel Sargent; Q Shi; Greg Yothers; E Van Cutsem; J Cassidy; Leonard B Saltz; Norman Wolmark; B Bot; Axel Grothey; Marc Buyse; Aimery de Gramont
Two or three year disease-free survival (DFS) as a primary end-point in stage III adjuvant colon cancer trials with fluoropyrimidines with or without oxaliplatin or irinotecan: data from 12,676 patients from MOSAIC, X-ACT, PETACC-3, C-06, C-07 and C89803.
European journal of cancer (Oxford, England : 1990) 2011;47(7):990-6.
2011: Christine Desmedt; Angelo Di Leo; Evandro de Azambuja; Denis Larsimont; Benjamin Haibe-Kains; Jean Selleslags; Suzette Delaloge; Caroline Duhem; Jean-Pierre Kains; Birgit Carly; Marie Maerevoet; Anita Vindevoghel; Ghizlane Rouas; Françoise Lallemand; Virginie Durbecq; Fatima Cardoso; Roberto Salgado; Rodrigo Rovere; Gianluca Bontempi; Stefan Michiels; Marc Buyse; Jean-Marie Nogaret; Yuan Qi; Fraser Symmans; Lajos Pusztai; Véronique D'Hondt; Martine J Piccart-Gebhart; C Sotiriou
Multifactorial approach to predicting resistance to anthracyclines.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(12):1578-86.
2011: Marc Buyse; Stefan Michiels; Daniel J Sargent; Axel Grothey; Alastair Matheson; Aimery de Gramont
Integrating biomarkers in clinical trials.
Expert review of molecular diagnostics 2011;11(2):171-82.
2011: Michael F Press; Guido Sauter; Marc Buyse; Leslie Bernstein; Roberta Guzman; Angela Santiago; Ivonne E Villalobos; Wolfgang Eiermann; Tadeusz Pienkowski; Miguel Martin; Nicholas Robert; John Crown; Valerie Bee; Henry Taupin; Kerry J Flom; Isabelle Tabah-Fisch; Giovanni Pauletti; Mary-Ann Lindsay; Alessandro Riva; Dennis J Slamon
Alteration of topoisomerase II-alpha gene in human breast cancer: association with responsiveness to anthracycline-based chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(7):859-67.
2010: Aimery de Gramont; Joleen Hubbard; Qian Shi; Michael J O'Connell; Marc Buyse; Jacqueline K Benedetti; Brian Bot; Chris O'Callaghan; Greg Yothers; Richard M Goldberg; Charles D Blanke; Al Benson; Qiqi Deng; Steven R Alberts; Thierry Andre; Norman Wolmark; Axel Grothey; Daniel Sargent
Association between disease-free survival and overall survival when survival is prolonged after recurrence in patients receiving cytotoxic adjuvant therapy for colon cancer: simulations based on the 20,800 patient ACCENT data set.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(3):460-5.
2010: Mitch Dowsett; Jack Cuzick; Jim Ingle; Alan Coates; John Forbes; Judith M Bliss; Marc Buyse; Michael Baum; Aman Buzdar; Marco Colleoni; Charles Coombes; Claire Snowdon; Michael Gnant; Raimund Jakesz; Manfred Kaufmann; Francesco Boccardo; Jon Godwin; Christina Davies; Richard Peto
Meta-analysis of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(3):509-18.
2010: E D Saad; A Katz; P M Hoff; Marc Buyse
Progression-free survival as surrogate and as true end point: insights from the breast and colorectal cancer literature.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2010;21(1):7-12.
2009: Marc Buyse
Use of meta-analysis for the validation of surrogate endpoints and biomarkers in cancer trials.
Cancer journal (Sudbury, Mass.) 2009;15(5):421-5.
2009: B Chibaudel; C Tournigand; P Artru; T André; A Cervantes; A Figer; G Lledo; M Flesch; Marc Buyse; L Mineur; E Carola; F Rivera; N Perez-Staub; C Louvet; A de Gramont
FOLFOX in patients with metastatic colorectal cancer and high alkaline phosphatase level: an exploratory cohort of the GERCOR OPTIMOX1 study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(8):1383-6.
2009: Hubert Piessevaux; Marc Buyse; W De Roock; H Prenen; M Schlichting; Eric Van Cutsem; S Tejpar
Radiological tumor size decrease at week 6 is a potent predictor of outcome in chemorefractory metastatic colorectal cancer treated with cetuximab (BOND trial).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(8):1375-82.
2009: Marc Buyse
Contributions of meta-analyses based on individual patient data to therapeutic progress in colorectal cancer.
International journal of clinical oncology 2009;14(2):95-101.
2009: Stefan Michiels; Aurélie Le Maître; Marc Buyse; Tomasz Burzykowski; Emilie Maillard; Jan Bogaerts; Jan B Vermorken; Wilfried Budach; Thomas F Pajak; Kian K Ang; Jean Bourhis; Jean-Pierre Pignon
Surrogate endpoints for overall survival in locally advanced head and neck cancer: meta-analyses of individual patient data.
The lancet oncology 2009;10(4):341-50.
2009: Christine Desmedt; Jeff Sperinde; Fanny Piette; Weidong Huang; Xueguang Jin; Yuping Tan; Virginie Durbecq; Denis Larsimont; Rosa Giuliani; Colombe Chappey; Marc Buyse; John Winslow; Martine Piccart; C Sotiriou; Christos Petropoulos; Michael Bates
Quantitation of HER2 expression or HER2:HER2 dimers and differential survival in a cohort of metastatic breast cancer patients carefully selected for trastuzumab treatment primarily by FISH.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2009;18(1):22-9.
2009: Daniel Sargent; Alberto Sobrero; Axel Grothey; Michael J O'Connell; Marc Buyse; Thierry Andre; Yan Zheng; Erin Green; Roberto Labianca; Chris O'Callaghan; Jean Francois Seitz; Guido Francini; Daniel Haller; Greg Yothers; Richard M Goldberg; Aimery de Gramont
Evidence for cure by adjuvant therapy in colon cancer: observations based on individual patient data from 20,898 patients on 18 randomized trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(6):872-7.
2008: Marc Buyse; Tomasz Burzykowski; Stefan Michiels; Kevin Carroll
Individual- and trial-level surrogacy in colorectal cancer.
Statistical methods in medical research 2008;17(5):467-75.
2008: Christine Desmedt; Benjamin Haibe-Kains; Pratyaksha Wirapati; Marc Buyse; Denis Larsimont; Gianluca Bontempi; Mauro Delorenzi; Martine Piccart; C Sotiriou
Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(16):5158-65.
2008: Stephanie R Land; Judith Abrams; Marc Buyse; Richard J Chappell
Statistics in oncology.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(22):3668.
2008: Pascal Piedbois; Marc Buyse
Endpoints and surrogate endpoints in colorectal cancer: a review of recent developments.
Current opinion in oncology 2008;20(4):466-71.
2008: Tomasz Burzykowski; Marc Buyse; Martine J Piccart-Gebhart; George Sledge; James Carmichael; Hans-Joachim Lück; John R Mackey; Jean-Marc Nabholtz; Robert Paridaens; Laura Biganzoli; Jacek Jassem; Marijke Bontenbal; Jacques Bonneterre; Stephen Chan; Gul Atalay Basaran; Patrick Therasse
Evaluation of tumor response, disease control, progression-free survival, and time to progression as potential surrogate end points in metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(12):1987-92.
2008: Martine J Piccart-Gebhart; Tomasz Burzykowski; Marc Buyse; George Sledge; James Carmichael; Hans-Joachim Lück; John R Mackey; Jean-Marc Nabholtz; Robert Paridaens; Laura Biganzoli; Jacek Jassem; Marijke Bontenbal; Jacques Bonneterre; Stephen Chan; Gul Atalay Basaran; Patrick Therasse
Taxanes alone or in combination with anthracyclines as first-line therapy of patients with metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(12):1980-6.
2008: Tomasz Burzykowski; Marc Buyse; Greg Yothers; Junichi Sakamoto; Dan Sargent
Exploring and validating surrogate endpoints in colorectal cancer.
Lifetime data analysis 2008;14(1):54-64.
2008: P Francis; John Crown; Angelo Di Leo; Marc Buyse; Ana Balil; Michael Andersson; Bo Nordenskjöld; Istvan Lang; Raimund Jakesz; Daniel Vorobiof; Jorge Gutiérrez; Guy Van Hazel; Stella Dolci; Sophie Jamin; Belguendouz Bendahmane; Richard D Gelber; Aron Goldhirsch; Monica Castiglione-Gertsch; Martine Piccart-Gebhart
Adjuvant chemotherapy with sequential or concurrent anthracycline and docetaxel: Breast International Group 02-98 randomized trial.
Journal of the National Cancer Institute 2008;100(2):121-33.
2008: Marc Buyse
Reformulating the hazard ratio to enhance communication with clinical investigators.
Clinical trials (London, England) 2008;5(6):641-2.
2008: Benjamin Haibe-Kains; Christine Desmedt; Fanny Piette; Marc Buyse; Fatima Cardoso; Laura Van't Veer; Martine Piccart; Gianluca Bontempi; Christos Sotiriou
Comparison of prognostic gene expression signatures for breast cancer.
BMC genomics 2008;9():394.
2008: Colin Baigent; Frank E Harrell; Marc Buyse; Jonathan R Emberson; Douglas Altman
Ensuring trial validity by data quality assurance and diversification of monitoring methods.
Clinical trials (London, England) 2008;5(1):49-55.
2007: Laurence Collette; Marc Buyse; Tomasz Burzykowski
Are prostate-specific antigen changes valid surrogates for survival in hormone-refractory prostate cancer? A meta-analysis is needed!
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(35):5673-4; author reply 5674.
2007: Marc Buyse; Tomasz Burzykowski; Kevin Carroll; Stefan Michiels; Daniel J Sargent; Langdon L Miller; Gary L Elfring; Jean-Pierre Pignon; Pascal Piedbois
Progression-free survival is a surrogate for survival in advanced colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(33):5218-24.
2007: Daniel J Sargent; Smitha Patiyil; Greg Yothers; Daniel G Haller; Richard Gray; Jacqueline K Benedetti; Marc Buyse; Roberto Labianca; Jean Francois Seitz; Christopher J O'Callaghan; Guido Francini; Axel Grothey; Michael O'Connell; Paul J Catalano; David Kerr; Erin Green; H Samuel Wieand; Richard M Goldberg; Aimery de Gramont
End points for colon cancer adjuvant trials: observations and recommendations based on individual patient data from 20,898 patients enrolled onto 18 randomized trials from the ACCENT Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(29):4569-74.
2007: Thierry André; Emmanuel Quinaux; Christophe Louvet; Philippe Colin; Erick Gamelin; Olivier Bouche; Emmanuel Achille; Pascal Piedbois; Nicole Tubiana-Mathieu; Arnaud Boutan-Laroze; Michel Flesch; Gérard Lledo; Yves Raoul; Isabelle Debrix; Marc Buyse; Aimery de Gramont
Phase III study comparing a semimonthly with a monthly regimen of fluorouracil and leucovorin as adjuvant treatment for stage II and III colon cancer patients: final results of GERCOR C96.1.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(24):3732-8.
2007: Carmen Allegra; Charles D Blanke; Marc Buyse; Richard M Goldberg; Axel Grothey; Neal J Meropol; Leonard B Saltz; Alan P Venook; Greg Yothers; Daniel Sargent
End points in advanced colon cancer clinical trials: a review and proposal.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(24):3572-5.
2007: Aimery de Gramont; Marc Buyse; Jose Cortinas Abrahantes; Tomasz Burzykowski; Emmanuel Quinaux; Andrés Cervantes; Arie Figer; Gérard Lledo; Michel Flesch; Laurent Mineur; Elisabeth Carola; Pierre-Luc Etienne; Fernando Rivera; Isabel Chirivella; Nathalie Perez-Staub; Christophe Louvet; Thierry André; Isabelle Tabah-Fisch; Christophe Tournigand
Reintroduction of oxaliplatin is associated with improved survival in advanced colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(22):3224-9.
2007: Cornelis J A Punt; Marc Buyse; Claus-Henning Köhne; Peter Hohenberger; Roberto Labianca; Hans J Schmoll; Lars Påhlman; Alberto Sobrero; Jean-Yves Douillard
Endpoints in adjuvant treatment trials: a systematic review of the literature in colon cancer and proposed definitions for future trials.
Journal of the National Cancer Institute 2007;99(13):998-1003.
2007: Christine Desmedt; Fanny Piette; Sherene Loi; Yixin Wang; Françoise Lallemand; Benjamin Haibe-Kains; Giuseppe Viale; Mauro Delorenzi; Yi Zhang; Mahasti Saghatchian d'Assignies; Jonas Bergh; Rosette Lidereau; Paul Ellis; Adrian L Harris; Jan G M Klijn; John A Foekens; Fatima Cardoso; Martine J Piccart; Marc Buyse; Christos Sotiriou
Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(11):3207-14.
2007: Sherene Loi; Benjamin Haibe-Kains; Christine Desmedt; Françoise Lallemand; Andrew M Tutt; Cheryl Gillet; Paul Ellis; Adrian Harris; Jonas Bergh; John A Foekens; Jan G M Klijn; Denis Larsimont; Marc Buyse; Gianluca Bontempi; Mauro Delorenzi; Martine J Piccart; Christos Sotiriou
Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(10):1239-46.
2007: Marissa Lassere; Kent Johnson; Michael Hughes; Doug Altman; Marc Buyse; Sally Galbraith; George Wells
Simulation studies of surrogate endpoint validation using single trial and multitrial statistical approaches.
The Journal of rheumatology 2007;34(3):616-9.
2007: Marissa Lassere; Kent R Johnson; Maarten Boers; Peter Tugwell; Peter Brooks; Lee Simon; Vibeke Strand; Philip Conaghan; Mikkel Ostergaard; Walter P Maksymowych; Robert Landewe; Barry Bresnihan; Paul P Tak; Richard J Wakefield; Philip J Mease; Clifton O Bingham; Michael Hughes; Doug Altman; Marc Buyse; Sally Galbraith; George Wells
Definitions and validation criteria for biomarkers and surrogate endpoints: development and testing of a quantitative hierarchical levels of evidence schema.
The Journal of rheumatology 2007;34(3):607-15.
2007: Joseph R. Zelefsky; Muthaiah Srinivasan; Arunava Kundu; Thomas Lietman; John P Whitcher; Kun Wang; Marc Buyse; Emmett T Cunningham
Hookworm infestation as a risk factor for Mooren's ulcer in South India.
Ophthalmology 2007;114(3):450-3.
2007: Pascal Piedbois; Daniel Serin; Frank Priou; P Laplaige; S Greget; E Angellier; E Teissier; J-F Berdah; M Fabbro; B Valenza; P Herait; V Jehl; Marc Buyse
Dose-dense adjuvant chemotherapy in node-positive breast cancer: docetaxel followed by epirubicin/cyclophosphamide (T/EC), or the reverse sequence (EC/T), every 2 weeks, versus docetaxel, epirubicin and cyclophosphamide (TEC) every 3 weeks. AERO B03 randomized phase II study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(1):52-7.
2006: Christine Desmedt; Frank El Ouriaghli; Virginie Durbecq; Anne Soree; Mariantonietta Colozza; Evandro Azambuja; Marianne Paesmans; Denis Larsimont; Marc Buyse; Adrian Harris; Martine Piccart; Philippe Martiat; Christos Sotiriou
Impact of cyclins E, neutrophil elastase and proteinase 3 expression levels on clinical outcome in primary breast cancer patients.
International journal of cancer. Journal international du cancer 2006;119(11):2539-45.
2006: Jan Bogaerts; Fatima Cardoso; Marc Buyse; Sofia Braga; Sherene Loi; Jillian A Harrison; Jacques Bines; Stella Mook; Nuria Decker; Peter M Ravdin; Patrick Therasse; Emiel Rutgers; Laura J van 't Veer; Martine Piccart
Gene signature evaluation as a prognostic tool: challenges in the design of the MINDACT trial.
Nature clinical practice. Oncology 2006;3(10):540-51.
2006: Marc Buyse; Sherene Loi; Laura J van't Veer; Giuseppe Viale; Mauro Delorenzi; Annuska M Glas; Mahasti Saghatchian d'Assignies; Jonas Bergh; Rosette Lidereau; Paul Ellis; Adrian Harris; Jan Bogaerts; Patrick Therasse; Arno N Floore; Mohamed Amakrane; Fanny Piette; Emiel Rutgers; Christos Sotiriou; Fatima Cardoso; Martine J Piccart
Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer.
Journal of the National Cancer Institute 2006;98(17):1183-92.
2006: Rob Glynne-Jones; Suzannah Mawdsley; T Pearce; Marc Buyse
Alternative clinical end points in rectal cancer--are we getting closer?
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(8):1239-48.
2006: Tomasz Burzykowski; Marc Buyse
Surrogate threshold effect: an alternative measure for meta-analytic surrogate endpoint validation.
Pharmaceutical statistics 2006;5(3):173-86.
2006: Patrick Therasse; Elizabeth A Eisenhauer; Marc Buyse
Update in methodology and conduct of cancer clinical trials.
European journal of cancer (Oxford, England : 1990) 2006;42(10):1322-30.
2006: Thierry André; Daniel Sargent; Josep Tabernero; Michael O'Connell; Marc Buyse; Alberto Sobrero; Jean-Louis Misset; Corrado Boni; Aimery de Gramont
Current issues in adjuvant treatment of stage II colon cancer.
Annals of surgical oncology 2006;13(6):887-98.
2006: Christos Sotiriou; Pratyaksha Wirapati; Sherene Loi; Adrian Harris; Steve Fox; Johanna Smeds; Hans Nordgren; Pierre Farmer; Viviane Praz; Benjamin Haibe-Kains; Christine Desmedt; Denis Larsimont; Fatima Cardoso; Hans L Peterse; Dimitry S A Nuyten; Marc Buyse; Marc J van de Vijver; Jonas Bergh; Martine Piccart; Mauro Delorenzi
Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis.
Journal of the National Cancer Institute 2006;98(4):262-72.
2006: Sherene Loi; Christos Sotiriou; Marc Buyse; Emiel Rutgers; Laura J van't Veer; Martine Piccart; Fatima Cardoso
Molecular forecasting of breast cancer: time to move forward with clinical testing.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(4):721-2; author reply 722-3.
2006: Ariel Alonso; Geert Molenberghs; Helena Geys; Marc Buyse; Tony Vangeneugden
A unifying approach for surrogate marker validation based on Prentice's criteria.
Statistics in medicine 2006;25(2):205-21.
2006: Christophe Tournigand; Andrés Cervantes; Arie Figer; Gérard Lledo; Michel Flesch; Marc Buyse; Laurent Mineur; Elisabeth Carola; Pierre-Luc Etienne; Fernando Rivera; Isabel Chirivella; Nathalie Perez-Staub; Christophe Louvet; Thierry André; Isabelle Tabah-Fisch; Aimery de Gramont
OPTIMOX1: a randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer--a GERCOR study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(3):394-400.
2006: J-L Liénard; Emmanuel Quinaux; Elizabeth Fabre-Guillevin; Pascal Piedbois; A Jouhaud; G Decoster; Marc Buyse
Impact of on-site initiation visits on patient recruitment and data quality in a randomized trial of adjuvant chemotherapy for breast cancer.
Clinical trials (London, England) 2006;3(5):486-92.
2005: Daniel J Sargent; H Samuel Wieand; Daniel G Haller; Richard Gray; Jacqueline K Benedetti; Marc Buyse; Roberto Labianca; Jean Francois Seitz; Christopher J O'Callaghan; Guido Francini; Axel Grothey; Michael O'Connell; Paul J Catalano; Charles D Blanke; David Kerr; Erin Green; Norman Wolmark; Thierry Andre; Richard M Goldberg; Aimery de Gramont
Disease-free survival versus overall survival as a primary end point for adjuvant colon cancer studies: individual patient data from 20,898 patients on 18 randomized trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(34):8664-70.
2004: Véronique Diéras; Pierre Fumoleau; Gilles Romieu; Michèle Tubiana-Hulin; Moïse Namer; Louis Mauriac; Jean-Paul Guastalla; Eric Pujade-Lauraine; Pierre Kerbrat; Philippe Maillart; Frédérique Pénault-Llorca; Marc Buyse; Pierre Pouillart
Randomized parallel study of doxorubicin plus paclitaxel and doxorubicin plus cyclophosphamide as neoadjuvant treatment of patients with breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(24):4958-65.
2004: Sherene Loi; Marc Buyse; Christos Sotiriou; Fatima Cardoso
Challenges in breast cancer clinical trial design in the postgenomic era.
Current opinion in oncology 2004;16(6):536-41.
2004: Pascal Piedbois; Marc Buyse
Meta-analyses based on abstracted data: a step in the right direction, but only a first step.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(19):3839-41.
2004: P Thirion; Stefan Michiels; Jean-Pierre Pignon; Marc Buyse; Anne-Chantal Braud; R W Carlson; M O'Connell; P Sargent; Pascal Piedbois
Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: an updated meta-analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(18):3766-75.
2004: Ariel Alonso; Geert Molenberghs; Tomasz Burzykowski; Didier Renard; Helena Geys; Ziv Shkedy; Fabián Tibaldi; José Cortiñas Abrahantes; Marc Buyse
Prentice's approach and the meta-analytic paradigm: a reflection on the role of statistics in the evaluation of surrogate endpoints.
Biometrics 2004;60(3):724-8.
2004: Geert Molenberghs; Tomasz Burzykowski; Ariel Alonso; Marc Buyse
A perspective on surrogate endpoints in controlled clinical trials.
Statistical methods in medical research 2004;13(3):177-206.
2004: A Di Leo; Marc Buyse; H Bleiberg
Is overall survival a realistic primary end point in advanced colorectal cancer studies? A critical assessment based on four clinical trials comparing fluorouracil plus leucovorin with the same treatment combined either with oxaliplatin or with CPT-11.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(4):545-9.
2004: Junichi Sakamoto; Yasuo Ohashi; Chikuma Hamada; Marc Buyse; Tomasz Burzykowski; Pascal Piedbois
Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(3):484-92.
2004: Christophe Tournigand; Thierry André; Emmanuel Achille; Gérard Lledo; Michel Flesh; Dominique Mery-Mignard; Emmanuel Quinaux; Corinne Couteau; Marc Buyse; Gérard Ganem; Bruno Landi; Philippe Colin; Christophe Louvet; Aimery de Gramont
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(2):229-37.
2003: Elizabeth Fabre-Guillevin; Pascal Piedbois; Marc Buyse
Progress in the medical treatment of advanced colorectal cancer.
Expert review of anticancer therapy 2003;3(5):711-6.
2003: Laurent Zelek; Roland Bugat; Daniel Cherqui; Gérard Ganem; P Valleur; Rosine Guimbaud; O Dupuis; T Aziza; Pierre-Louis Fagniez; Jean Auroux; Hicham Kobeiter; Claude Tayar; Anne-Chantal Braud; E Haddad; Alain Piolot; Marc Buyse; Pascal Piedbois
Multimodal therapy with intravenous biweekly leucovorin, 5-fluorouracil and irinotecan combined with hepatic arterial infusion pirarubicin in non-resectable hepatic metastases from colorectal cancer (a European Association for Research in Oncology trial).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(10):1537-42.
2003: Thierry Andre; Philippe Colin; Christophe Louvet; Erick Gamelin; Olivier Bouche; Emmanuel Achille; Nicolas Colbert; Catherine Boaziz; Pascal Piedbois; Nicole Tubiana-Mathieu; Arnaud Boutan-Laroze; Michel Flesch; Marc Buyse; Aimery de Gramont
Semimonthly versus monthly regimen of fluorouracil and leucovorin administered for 24 or 36 weeks as adjuvant therapy in stage II and III colon cancer: results of a randomized trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(15):2896-903.
2003: Angelo Di Leo; Harry Bleiberg; Marc Buyse
Overall survival is not a realistic end point for clinical trials of new drugs in advanced solid tumors: a critical assessment based on recently reported phase III trials in colorectal and breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(10):2045-7.
2003: Marc Buyse; Tomasz Burzykowski; Mahesh Parmar; Valter Torri; George Omura; Nicoletta Colombo; Chris Williams; Pierfranco Conte; Jan Vermorken
Using the expected survival to explain differences between the results of randomized trials: a case in advanced ovarian cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(9):1682-7.
2003: Marc Buyse
Phase III clinical trials in oncology. 20-21 January 2003, London, UK.
IDrugs : the investigational drugs journal 2003;6(3):187-90.
2003: Philippe Autier; Peter Boyle; Marc Buyse; Harry Bleiberg
Is FOB screening really the answer for lowering mortality in colorectal cancer?
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;163():254-63; discussion 264-6.
2002: Geert Molenberghs; Marc Buyse; Helena Geys; Didier Renard; Tomasz Burzykowski; Ariel Alonso
Statistical challenges in the evaluation of surrogate endpoints in randomized trials.
Controlled clinical trials 2002;23(6):607-25.
2002: Laurent Zelek; Pascal Piedbois; Marc Buyse
Contribution of meta-analyses to the evaluation of treatments for advanced colorectal cancer.
Expert review of anticancer therapy 2002;2(4):417-25.
2002: V Trillet-Lenoir; P Piedbois; Marc Buyse
The role of colony stimulating factors in small cell lung cancer: why the question is still unsolved.
Lung cancer (Amsterdam, Netherlands) 2002;37(2):125-6.
2002: Angelo Di Leo; Marc Buyse
Equivalence between ovarian suppression and chemotherapy in the adjuvant treatment of endocrine-responsive breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(7):1954-5.
2001: Geert Molenberghs; Helena Geys; Marc Buyse
Evaluation of surrogate endpoints in randomized experiments with mixed discrete and continuous outcomes.
Statistics in medicine 2001;20(20):3023-38.
2001: Marc Buyse; P Thirion; R W Carlson; Tomasz Burzykowski; G Molenberghs; Pascal Piedbois
Re: A model to select chemotherapy regimens for phase III trials for extensive-stage small-cell lung cancer.
Journal of the National Cancer Institute 2001;93(5):399-401.
2001: P Thirion; Pascal Piedbois; Marc Buyse; P J O'Dwyer; D Cunningham; A Man; F A Greco; G Colucci; C H Köhne; F Di Constanzo; A Piga; S Palmeri; P Dufour; A Cassano; G Pajkos; R A Pensel; N F Aykan; J Marsh; M T Seymour
Alpha-interferon does not increase the efficacy of 5-fluorouracil in advanced colorectal cancer.
British journal of cancer 2001;84(5):611-20.
2001: Thierry André; Philippe Colin; Christophe Louvet; Erick Gamelin; Olivier Bouche; Emmanuel Achille; N Colbert; Catherine Boaziz; Pascal Piedbois; Nicole Tubiana-Mathieu; Arnaud Boutan-Laroze; Michel Flesch; V Billiau; Marc Buyse; A Gramont
Randomized adjuvant study comparing two schemes of 5-fluorouracil and leucovorin in stage B2 and C colon adenocarcinoma: study design and preliminary safety results. Groupe d'Etude et de Recherche Clinique en Oncologie Radiotherapies.
Seminars in oncology 2001;28(1 Suppl 1):35-40.
2001: Marc Buyse; Pascal Piedbois
Should Dukes' B patients receive adjuvant therapy? A statistical perspective.
Seminars in oncology 2001;28(1 Suppl 1):20-4.
2001: Martine J Piccart; Caroline Lohrisch; Luc Duchateau; Marc Buyse
Taxanes in the adjuvant treatment of breast cancer: why not yet?
Journal of the National Cancer Institute. Monographs 2001;(30):88-95.
2000: Jonas Ranstam; Marc Buyse; S L George; S Evans; N L Geller; B Scherrer; E Lesaffre; G Murray; L Edler; Jane L Hutton; T Colton; P Lachenbruch
Fraud in medical research: an international survey of biostatisticians. ISCB Subcommittee on Fraud.
Controlled clinical trials 2000;21(5):415-27.
2000: Marc Buyse; Youri Piedbois; Pascal Piedbois; Richard Gray
Tumour site, sex, and survival in colorectal cancer.
Lancet 2000;356(9232):858.
2000: Marc Buyse; P Thirion; R W Carlson; Tomasz Burzykowski; G Molenberghs; Pascal Piedbois
Relation between tumour response to first-line chemotherapy and survival in advanced colorectal cancer: a meta-analysis. Meta-Analysis Group in Cancer.
Lancet 2000;356(9227):373-8.
2000: P Piedbois; Marc Buyse
Recent meta-analyses in colorectal cancer.
Current opinion in oncology 2000;12(4):362-7.
2000: Marc Buyse; Pascal Piedbois; Youri Piedbois; R W Carlson
Meta-analysis: methods, strengths, and weaknesses.
Oncology (Williston Park, N.Y.) 2000;14(3):437-43; discussion 444, 447.
2000: Marc Buyse
R(2): a useful measure of model performance when predicting a dichotomous outcome.
Statistics in medicine 2000;19(2):271-4.
2000: D Sharma; Marc Buyse; Bertram Pitt; E J Rucinska
Meta-analysis of observed mortality data from all-controlled, double-blind, multiple-dose studies of losartan in heart failure. Losartan Heart Failure Mortality Meta-analysis Study Group.
The American journal of cardiology 2000;85(2):187-92.
1999: Marc Buyse; S L George; S Evans; N L Geller; Jonas Ranstam; B Scherrer; E Lesaffre; G Murray; L Edler; Jane L Hutton; T Colton; P Lachenbruch; B L Verma
The role of biostatistics in the prevention, detection and treatment of fraud in clinical trials.
Statistics in medicine 1999;18(24):3435-51.
1999: P Thirion; N Wolmark; E Haddad; Marc Buyse; Pascal Piedbois
Survival impact of chemotherapy in patients with colorectal metastases confined to the liver: a re-analysis of 1458 non-operable patients randomised in 22 trials and 4 meta-analyses. Meta-Analysis Group in Cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(11):1317-20.
1999: I Durand-Zaleski; B Roche; Marc Buyse; R Carlson; M O'Connell; P Rougier; Alfred E Chang; vernon sondak; M Kemeny; T Allen-Mersh; Pierre-Louis Fagniez; Jean-Paul Le Bourgeois; Pascal Piedbois
Economic implications of hepatic arterial infusion versus intravenous chemotherapy or symptom palliation in the treatment of nonresectable colorectal liver metastases. Meta-Analysis Group In Cancer.
Critical reviews in oncology/hematology 1999;32(2):125-31.
1999: Jean-Pierre Boissel; Michel Cucherat; G Chatellier; Marc Buyse; W Li; Florent Boutitie; Patrice Nony; François Gueyffier; Margaret Haugh; G Mignot
[Outline of the problem of indices of therapeutic efficacy. 4. Expression of efficacy when the underlying illness is incurable. Study Group for the Indices of Efficacy].
Thérapie 1999;54(5):519-23.
1999: Jean-Pierre Boissel; Michel Cucherat; W Li; G Chatellier; François Gueyffier; Marc Buyse; Florent Boutitie; Patrice Nony; Margaret Haugh; G Mignot
[The problem of therapeutic efficacy indices. 3. Comparison of the indices and their use].
Thérapie 1999;54(4):405-11.
1999: Jean-Pierre Boissel; Marc Buyse; Michel Cucherat; Florent Boutitie; François Gueyffier; G Chatellier; W Li; Patrice Nony; Margaret Haugh; G Mignot
[The problem of therapeutic efficacy indices. 2. Description of the indices].
Thérapie 1999;54(3):309-14.
1999: Marc Buyse; R W Carlson; P Piedbois
Meta-analyses of published results are unreliable.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(5):1646-7.
1999: Jean-Pierre Boissel; Michel Cucherat; François Gueyffier; G Chatellier; Marc Buyse; W Li; Florent Boutitie; Patrice Nony; Margaret Haugh; G Mignot
[The problem of therapeutic efficacy indices. 1. Elements of the problem].
Thérapie 1999;54(2):203-7.
1999: Jan B Vermorken; P G Harper; Marc Buyse
The role of anthracyclines in epithelial ovarian cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10 Suppl 1():43-50.
1999: Godehard Friedel; U Pastorino; Marc Buyse; R J Ginsberg; P Girard; P Goldstraw; M Johnston; P McCormack; Harvey I Pass; J B Putnam; Heikki Toomes
[Resection of lung metastases: long-term results and prognostic analysis based on 5206 cases--the International Registry of Lung Metastases].
Zentralblatt für Chirurgie 1999;124(2):96-103.
1998: P Piedbois; Marc Buyse
[Randomizations!].
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique 1998;2(6):663-4.
1998: K Aabo; M Adams; P Adnitt; D S Alberts; A Athanazziou; V Barley; D R Bell; U Bianchi; Giorgio Bolis; M F Brady; H S Brodovsky; H Bruckner; Marc Buyse; R Canetta; V Chylak; C J Cohen; Nicoletta Colombo; P F Conte; D Crowther; J H Edmonson; C Gennatas; E Gilbey; M Gore; D Guthrie; B Y Yeap
Chemotherapy in advanced ovarian cancer: four systematic meta-analyses of individual patient data from 37 randomized trials. Advanced Ovarian Cancer Trialists' Group.
British journal of cancer 1998;78(11):1479-87.
1998: H Bleiberg; F Hulstaert; Marc Buyse; P De Keyser
Tropisetron in the prevention of acute and delayed nausea and vomiting over six courses of emetogenic chemotherapy.
Anti-cancer drugs 1998;9(9):773-7.
1998: Jacques Bartholeyns; jean-loup romet-lemonne; Mohamed Chokri; Marc Buyse; Thierry Velu; Catherine Bruyns; J J Van de Winkel; Jonathan Luke Heeney; Gerrit Koopman; M Malmsten; D De Groote; Michel Monsigny; Patrick Midoux; B Alarcon
Cellular vaccines.
Research in immunology 1998;149(7-8):647-9.
1998: Marc Buyse; G Molenberghs
Criteria for the validation of surrogate endpoints in randomized experiments.
Biometrics 1998;54(3):1014-29.
1998: Francis Corazza; Y Beguin; Pierre Bergmann; M André; Alina Ferster; Christine Devalck; Pierre Fondu; Marc Buyse; Eric Sariban
Anemia in children with cancer is associated with decreased erythropoietic activity and not with inadequate erythropoietin production.
Blood 1998;92(5):1793-8.
1997: Marc Buyse
A biostatistical tribute to Ignaz Philip Semmelweis.
Statistics in medicine 1997;16(24):2767-72.
1997: F Pezzella; Ugo Pastorino; Elda Tagliabue; Salvatore Andreola; Gabriella Sozzi; G Gasparini; S Menard; K C Gatter; A L Harris; S Fox; Marc Buyse; Silvana Pilotti; Marco A Pierotti; F Rilke
Non-small-cell lung carcinoma tumor growth without morphological evidence of neo-angiogenesis.
The American journal of pathology 1997;151(5):1417-23.
1997: Marc Buyse; P Piedbois
Artificial neural networks.
Lancet 1997;350(9085):1175-6.
1997: Ugo Pastorino; Salvatore Andreola; Elda Tagliabue; F Pezzella; Matteo Incarbone; Gabriella Sozzi; Marc Buyse; S Menard; Marco A Pierotti; F Rilke
Immunocytochemical markers in stage I lung cancer: relevance to prognosis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(8):2858-65.
1997: I Durand-Zaleski; B Roche; Marc Buyse; R Carlson; M J O'Connell; P Rougier; Alfred E Chang; vernon sondak; M M Kemeny; T G Allen-Mersh; Pierre-Louis Fagniez; Jean-Paul Le Bourgeois; Pascal Piedbois
Economic implications of hepatic arterial infusion chemotherapy in treatment of nonresectable colorectal liver metastases. Meta-Analysis Group in Cancer.
Journal of the National Cancer Institute 1997;89(11):790-5.
1997: R Peto; R Collins; D Sackett; Janet Darbyshire; A Babiker; Marc Buyse; H Stewart; Michael Baum; A Goldhirsch; G Bonadonna; P Valagussa; L Rutqvist; Diana Elbourne; C Davies; Otilia Dalesio; M Parmar; C Hill; Mike Clarke; Richard Gray; R Doll
The trials of Dr. Bernard Fisher: a European perspective on an American episode.
Controlled clinical trials 1997;18(1):1-13.
1996: Marc Buyse; P Piedbois
On the relationship between response to treatment and survival time.
Statistics in medicine 1996;15(24):2797-812.
1996: F A Greco; R Figlin; M York; L Einhorn; R Schilsky; E M Marshall; S S Buys; M J Froimtchuk; J Schuller; L Schuchter; Marc Buyse; L Ritter; A Man; A K Yap
Phase III randomized study to compare interferon alfa-2a in combination with fluorouracil versus fluorouracil alone in patients with advanced colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(10):2674-81.
1996: Alina Ferster; C Vermylen; G Cornu; Marc Buyse; Francis Corazza; Christine Devalck; Pierre Fondu; Michèle Toppet; Eric Sariban
Hydroxyurea for treatment of severe sickle cell anemia: a pediatric clinical trial.
Blood 1996;88(6):1960-4.
1995: Mario Lise; Donato Nitti; Alberto Marchet; TM Sahmoud; Marc Buyse; N Duez; M Fiorentino; J G Dos Santos; Roberto Labianca; P Rougier
Final results of a phase III clinical trial of adjuvant chemotherapy with the modified fluorouracil, doxorubicin, and mitomycin regimen in resectable gastric cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(11):2757-63.
1995: H Pouleur; Marc Buyse
Effects of dipyridamole in combination with anticoagulant therapy on survival and thromboembolic events in patients with prosthetic heart valves. A meta-analysis of the randomized trials.
The Journal of thoracic and cardiovascular surgery 1995;110(2):463-72.
1995: Marc Buyse; J L Poplavsky
Clinical evaluation of virus safety and inhibitor incidence: statistical considerations.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1995;6 Suppl 2():S86-92.
1995: S Schreiber; Marc Buyse
The CRP initial response to treatment as prognostic factor in patients with polymyalgia rheumatica.
Clinical rheumatology 1995;14(3):315-8.
1995: M E L van der Burg; M van Lent; Marc Buyse; A Kobierska; N Colombo; G Favalli; A J Lacave; M Nardi; J Renard; S Pecorelli
The effect of debulking surgery after induction chemotherapy on the prognosis in advanced epithelial ovarian cancer. Gynecological Cancer Cooperative Group of the European Organization for Research and Treatment of Cancer.
The New England journal of medicine 1995;332(10):629-34.
1995: S J Van Belle; Veronique Cocquyt; H Bleiberg; J L Canon; Marc Buyse; F Hulstaert; M De Witte; P De Keyser; K Westelinck
Optimal combination therapy with Navoban (tropisetron) in patients with incomplete control of chemotherapy-induced nausea and vomiting. The Belgian Navoban Group.
Anti-cancer drugs 1995;6 Suppl 1():22-30.
1995: P Piedbois; Marc Buyse
[A critical reading and interpretation of the results of phase III trials and meta-analysis].
Bulletin du cancer. Radiothérapie : journal de la Société française du cancer : organe de la société française de radiothérapie oncologique 1995;82(2):73-8.
1994: Pascal Piedbois; Marc Buyse
[Are meta-analyses reliable?].
La Revue du praticien 1994;44(18):2401-3.
1994: F Hulstaert; S Van Belle; H Bleiberg; J L Canon; M Dewitte; Marc Buyse; P De Keyser; K J Westelinck
Optimal combination therapy with tropisetron in 445 patients with incomplete control of chemotherapy-induced nausea and vomiting.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(11):2439-46.
1994: D Civalleri; J C Pector; L Håkansson; J P Arnaud; N Duez; Marc Buyse
Treatment of patients with irresectable liver metastases from colorectal cancer by chemo-occlusion with degradable starch microspheres.
The British journal of surgery 1994;81(9):1338-41.
1994: P Piedbois; Marc Buyse
Meta-analyses need time, collaboration, and funding.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(4):878-80.
1994: A Lowenthal; Marc Buyse
Secondary prevention of stroke: does dipyridamole add to aspirin?
Acta neurologica Belgica 1994;94(1):24-34.
1993: Marc Buyse
Meta-analysis of randomized clinical trials in cancer.
Gan to kagaku ryoho. Cancer & chemotherapy 1993;20(16):2501-6.
1993: Marc Buyse
Anecdotal clinical trials of the past.
Gan to kagaku ryoho. Cancer & chemotherapy 1993;20(16):2496-500.
1993: Ugo Pastorino; Maurizio Valentino Infante; M Maioli; G Chiesa; Marc Buyse; P Firket; N Rosmentz; M Clerici; E Soresi; M Valente
Adjuvant treatment of stage I lung cancer with high-dose vitamin A.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993;11(7):1216-22.
1993: Marc Buyse
Interim analyses, stopping rules and data monitoring in clinical trials in Europe.
Statistics in medicine 1993;12(5-6):509-20.
1993: Marc Buyse
Meta-analyses, use and misuse.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993;11(2):382.
1993: Pascal Piedbois; Marc Buyse
What can we learn from a meta-analysis of trials testing the modulation of 5-FU by leucovorin? Advanced Colorectal Meta-analysis Project.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1993;4 Suppl 2():15-9.
1993: Pascal Piedbois; E Lévy; J P Le Bourgeois; Marc Buyse
[Chemotherapy of metastasizing cancers of the colon and rectum].
Annales de chirurgie 1993;47(6):480-3.
1992: P Piedbois; Marc Buyse; Jean-Paul Le Bourgeois
[Meta-analysis, tool for synthesis and observation].
Bulletin du cancer 1992;79(10):951-6.
1991: Marc Buyse
Randomized clinical trials in surgical oncology.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1991;17(5):421-8.
1991: A Gerard; Marc Buyse; J C Pector; H Bleiberg; J P Arnaud; G Willems; G Delvaux; Mario Lise; Donato Nitti; G Depadt
Hepatic artery ligation with and without portal infusion of 5-FU. A randomized study in patients with unresectable liver metastases from colorectal carcinoma. The E.O.R.T.C. Gastrointestinal Cancer Cooperative Group (G.I. Group).
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1991;17(3):289-94.
1991: Jacques A Wils; H O Klein; D J Wagener; H Bleiberg; H Reis; Friedrich Korsten; Thierry Conroy; M Fickers; S Leyvraz; Marc Buyse
Sequential high-dose methotrexate and fluorouracil combined with doxorubicin--a step ahead in the treatment of advanced gastric cancer: a trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cooperative Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(5):827-31.
1990: Marc Buyse
The case of loose inclusion criteria in clinical trials.
Acta chirurgica Belgica 1990;90(3):129-31.
1990: J Hildebrand; F Bourgeois; Marc Buyse; Serge Przedborski; S Goldman
Reproducibility of monoamine metabolite measurements in human cerebrospinal fluid.
Acta neurologica Scandinavica 1990;81(5):427-30.
1990: Harry Bleiberg; B Vanderlinden; Marc Buyse; P Haegele; Bernard Paillot; A Tagnon; Jacques A Wils; G Cartei; A Fornasiero; N Duez
Randomized phase II study of a combination of cisplatin (DDP), 5-fluorouracil (5-FU), and allopurinol (HPP) versus 5-FU in advanced colorectal carcinoma. An EORTC Gastrointestinal Tract Cancer Cooperative Group study.
Cancer investigation 1990;8(5):471-5.
1990: Geert H Blijham; H Bleiberg; N Duez; Marc Buyse
An EORTC phase II study of sequential methotrexate-fluorouracil in locally advanced or metastatic gastric cancer. The EORTC Gastrointestinal Cancer Cooperative Group.
European journal of cancer (Oxford, England : 1990) 1990;26(1):63-5.
1989: H Bleiberg; J C Goffin; O Dalesio; Marc Buyse; J C Pector; M Gignoux; A Roussel; G Samana; J Michel; A Gerard
Adjuvant radiotherapy and chemotherapy in resectable gastric cancer. A randomized trial of the gastro-intestinal tract cancer cooperative group of the EORTC.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1989;15(6):535-43.
1989: Marc Buyse; M K Parmar
A meta-analysis of prognostic factors in advanced ovarian cancer with median survival and overall survival.
European journal of cancer & clinical oncology 1989;25(12):1901.
1989: Marc Buyse
Analysis of clinical trial outcomes: some comments on subgroup analyses.
Controlled clinical trials 1989;10(4 Suppl):187S-194S.
1989: P Recloux; P F Dodion; Guy Andry; G Chantrain; P Dor; Marc Buyse; P van Houtte; M Lemort; P Haesendonck; Denis Larsimont
Neoadjuvant chemotherapy with cisplatin, methotrexate, bleomycin and vincristine (CABO) in patients with stage III and IV squamous cell carcinoma of the head and neck.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1989;15(6):568-74.
1989: Jacques A Wils; H Bleiberg; Marc Buyse; D T Wagener; T Splinter; C Veenhof; M Herben; N Duez
An EORTC Gastrointestinal Group phase II evaluation of epirubicin combined with ifosfamide in advanced adenocarcinoma of the pancreas. EORTC Gastrointestinal Group.
European journal of cancer & clinical oncology 1989;25(7):1119-20.
1989: A Gerard; U Metzger; Marc Buyse
Adjuvant therapy in colorectal cancer.
Anticancer research 1989;9(4):1033-5.
1989: Mario Lise; Donato Nitti; Marc Buyse; Alberto Marchet; M Fiorentino; J G Dos Santos; N Duez
Adjuvant FAM2 in resectable gastric cancer.
Anticancer research 1989;9(4):1017-21.
1989: J P Arnaud; Marc Buyse; B Nordlinger; F Martin; J C Pector; P Zeitoun; A Adloff; N Duez
Adjuvant therapy of poor prognosis colon cancer with levamisole: results of an EORTC double-blind randomized clinical trial.
The British journal of surgery 1989;76(3):284-9.
1989: Marc Buyse
Potential and pitfalls of randomized clinical trials in cancer research.
Cancer surveys 1989;8(1):91-105.
1989: Marc Buyse; A Zeleniuch-Jacquotte; T C Chalmers
[Adjuvant chemotherapy of colorectal cancer: what can be learned from meta-analysis?].
Bulletin du cancer 1989;76(9):1021-8.
1989: H O Klein; J Wils; H Bleiberg; Marc Buyse; N Duez
An EORTC gastrointestinal (GI) group randomized evaluation of the toxicity of sequential high dose methotrexate and 5-fluorouracil combined with adriamycin (FAMTX) vs 5-fluorouracil, adriamycin and mitomycin (FAM) in advanced gastric cancer.
Medical oncology and tumor pharmacotherapy 1989;6(2):171-4.
1988: A Gérard; Marc Buyse; B Nordlinger; J Loygue; F Pène; P Kempf; J F Bosset; M Gignoux; J P Arnaud; C Desaive
Preoperative radiotherapy as adjuvant treatment in rectal cancer. Final results of a randomized study of the European Organization for Research and Treatment of Cancer (EORTC).
Annals of surgery 1988;208(5):606-14.
1988: Marc Buyse; A Zeleniuch-Jacquotte; T C Chalmers
Adjuvant therapy of colorectal cancer. Why we still don't know.
JAMA : the journal of the American Medical Association 1988;259(24):3571-8.
1988: Mario Lise; Donato Nitti; Marc Buyse; G Cartei; A Fornasiero; J Guimaraes dos Santos; N Duez
Phase-III clinical trial of adjuvant FAM2 (5-FU, adriamycin and mitomycin C) vs control in resectable gastric cancer: a study of the EORTC Gastrointestinal Tract Cancer Cooperative Group.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1988;110():36-43.
1988: A Gerard; J L Berrod; F Pene; J Loygue; A Laugier; R Bruckner; G Camelot; J P Arnaud; U Metzger; Marc Buyse
Preoperative radiotherapy and radical surgery as combined treatment in rectal cancer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1988;110():130-3.
1988: J P Arnaud; Marc Buyse; M Adloff; B Nordlinger; J C Pector; N Duez
Interim analysis of a double-blind phase-III clinical trial of adjuvant levamisole versus control in resectable Dukes-C colon cancer: a study of the EORTC Gastrointestinal Tract Cancer Cooperative Group.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1988;110():101-3.
1988: M Gignoux; A Roussel; Bernard Paillot; M Gillet; P Schlag; O Dalesio; Marc Buyse; N Duez
The value of preoperative radiotherapy in esophageal cancer: results of a study by the EORTC.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1988;110():1-13.
1987: Mario Lise; A Gerard; Donato Nitti; D Zane; Marc Buyse; N Duez; J P Arnaud; U Metzger
Adjuvant therapy for colorectal cancer. The EORTC experience and a review of the literature.
Diseases of the colon and rectum 1987;30(11):847-54.
1987: M Gignoux; A Roussel; Bernard Paillot; M Gillet; P Schlag; J P Favre; O Dalesio; Marc Buyse; N Duez
The value of preoperative radiotherapy in esophageal cancer: results of a study of the E.O.R.T.C.
World journal of surgery 1987;11(4):426-32.
1987: Marc Buyse; H Bleiberg
Counting and sampling errors: (mis)interpretation of data from tritiated thymidine labelled human tumors.
European journal of cancer & clinical oncology 1987;23(7):895-6.
1987: Marc Buyse; Louise M Ryan
Issues of efficiency in combining proportions of deaths from several clinical trials.
Statistics in medicine 1987;6(5):565-76.
1985: H Bleiberg; Marc Buyse; P Galand
Cell kinetic indicators of premalignant stages of colorectal cancer.
Cancer 1985;56(1):124-9.
1985: A Gerard; J L Berrod; F Pene; J Loygue; A Laugier; R Bruckner; G Camelot; J P Arnaud; U Metzger; Marc Buyse
Interim analysis of a phase III study on preoperative radiation therapy in resectable rectal carcinoma. Trial of the Gastrointestinal Tract Cancer Cooperative Group of the European Organization for Research on Treatment of Cancer (EORTC).
Cancer 1985;55(10):2373-9.
1984: S Boulis-Wassif; A Gerard; J Loygue; D Camelot; Marc Buyse; N Duez
Final results of a randomized trial on the treatment of rectal cancer with preoperative radiotherapy alone or in combination with 5-fluorouracil, followed by radical surgery. Trial of the European Organization on Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group.
Cancer 1984;53(9):1811-8.
1984: H Bleiberg; Marc Buyse; B van den Heule; P Galand
Cell cycle parameters and prognosis of colorectal cancer.
European journal of cancer & clinical oncology 1984;20(3):391-6.
1982: M Gignoux; Marc Buyse; P Segol; A Roussel; Bernard Paillot; A Kunlin; N Duez
[Multicenter randomized study comparing preoperative radiotherapy with surgery only in cases of resectable oesophageal cancer (author's transl)].
Acta chirurgica Belgica 1982;82(4):373-9.
1981: Alistair Cochran; Marc Buyse; F J Lejeune; E Macher; J Revuz; P Rümke
Adjuvant reactivity predicts survival in patients with "high-risk" primary malignant melanoma treated with systemic BCG. EORTC Malignant Melanoma Cooperative Group Writing Committee.
International journal of cancer. Journal international du cancer 1981;28(5):543-50.
1981: R J Sylvester; HERBERT PINEDO; M De Pauw; M J Staquet; Marc Buyse; J Renard; G Bonadonna
Quality of institutional participation in multicenter clinical trials.
The New England journal of medicine 1981;305(15):852-5.
1981: R Abele; J Bernheim; E Cumps; Marc Buyse; Y Kenis
Re-evaluation of the combination of CCNU, vincristine, and bleomycin in the treatment of malignant disseminated melanoma.
Cancer treatment reports 1981;65(5-6):505-6.
1981: A Gérard; M Gignoux; A Roussel; J C Goffin; A Brugarolas; P Zeitoun; F Martin; Marc Buyse; N Duez
Prospective and controlled studies on multidisciplinary treatment in gastrointestinal cancer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1981;79():19-27.