Peter Carmeliet

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Publications

TOP 3
Segura Inmaculada; De Smet Frederik; Hohensinner Philipp J; Almodovar Carmen Ruiz de; Carmeliet Peter
The neurovascular link in health and disease: an update.
Loges Sonja; Schmidt Thomas; Carmeliet Peter
"Antimyeloangiogenic" therapy for cancer by inhibiting PlGF.
De Bock Katrien; De Smet Frederik; Leite De Oliveira Rodrigo; Anthonis Kristof; Carmeliet Peter
Endothelial oxygen sensors regulate tumor vessel abnormalization by instructing phalanx endothelial cells.

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All Publications

2009: Segura Inmaculada; De Smet Frederik; Hohensinner Philipp J; Almodovar Carmen Ruiz de; Carmeliet Peter
The neurovascular link in health and disease: an update.
Trends in molecular medicine 2009;15(10):439-51.
2009: Loges Sonja; Schmidt Thomas; Carmeliet Peter
"Antimyeloangiogenic" therapy for cancer by inhibiting PlGF.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(11):3648-53.
2009: De Bock Katrien; De Smet Frederik; Leite De Oliveira Rodrigo; Anthonis Kristof; Carmeliet Peter
Endothelial oxygen sensors regulate tumor vessel abnormalization by instructing phalanx endothelial cells.
Journal of molecular medicine (Berlin, Germany) 2009;87(6):561-9.
2009: De Smet Frederik; Segura Inmaculada; De Bock Katrien; Hohensinner Philipp J; Carmeliet Peter
Mechanisms of vessel branching: filopodia on endothelial tip cells lead the way.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(5):639-49.
2009: Ruiz de Almodovar Carmen; Lambrechts Diether; Mazzone Massimiliano; Carmeliet Peter
Role and therapeutic potential of VEGF in the nervous system.
Physiological reviews 2009;89(2):607-48.
2009: Loges Sonja; Mazzone Massimiliano; Hohensinner Philipp; Carmeliet Peter
Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited.
Cancer cell 2009;15(3):167-70.
2009: Mazzone Massimiliano; Dettori Daniela; Leite de Oliveira Rodrigo; Loges Sonja; Schmidt Thomas; Jonckx Bart; Tian Ya-Min; Lanahan Anthony A; Pollard Patrick; Ruiz de Almodovar Carmen; De Smet Frederik; Vinckier Stefan; Aragonés Julián; Debackere Koen; Luttun Aernout; Wyns Sabine; Jordan Benedicte; Pisacane Alberto; Gallez Bernard; Lampugnani Maria Grazia; Dejana Elisabetta; Simons Michael; Ratcliffe Peter; Maxwell Patrick; Carmeliet Peter
Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.
Cell 2009;136(5):839-51.
2009: Zacchigna Serena; Oh Hideyasu; Wilsch-Bräuninger Michaela; Missol-Kolka Ewa; Jászai József; Jansen Sandra; Tanimoto Naoyuki; Tonagel Felix; Seeliger Mathias; Huttner Wieland B; Corbeil Denis; Dewerchin Mieke; Vinckier Stefan; Moons Lieve; Carmeliet Peter
Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(7):2297-308.
2009: Fraisl Peter; Mazzone Massimiliano; Schmidt Thomas; Carmeliet Peter
Regulation of angiogenesis by oxygen and metabolism.
Developmental cell 2009;16(2):167-79.
2009: Lähteenvuo Johanna E; Lähteenvuo Markku T; Kivelä Antti; Rosenlew Carolina; Falkevall Annelie; Klar Joakim; Heikura Tommi; Rissanen Tuomas T; Vähäkangas Elisa; Korpisalo Petra; Enholm Berndt; Carmeliet Peter; Alitalo Kari; Eriksson Ulf; Ylä-Herttuala Seppo
Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1- and neuropilin receptor-1-dependent mechanisms.
Circulation 2009;119(6):845-56.
2009: Fraisl Peter; Aragonés Julián; Carmeliet Peter
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease.
Nature reviews. Drug discovery 2009;8(2):139-52.
2009: Aragonés Julián; Fraisl Peter; Baes Myriam; Carmeliet Peter
Oxygen sensors at the crossroad of metabolism.
Cell metabolism 2009;9(1):11-22.
2009: Schellings Mark W M; Vanhoutte Davy; Swinnen Melissa; Cleutjens Jack P; Debets Jacques; van Leeuwen Rick E W; d'Hooge Jan; Van de Werf Frans; Carmeliet Peter; Pinto Yigal M; Sage E Helene; Heymans Stephane
Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction.
The Journal of experimental medicine 2009;206(1):113-23.
2009: Tintu Andrei; Rouwet Ellen; Verlohren Stefan; Brinkmann Joep; Ahmad Shakil; Crispi Fatima; van Bilsen Marc; Carmeliet Peter; Staff Anne Cathrine; Tjwa Marc; Cetin Irene; Gratacos Eduard; Hernandez-Andrade Edgar; Hofstra Leo; Jacobs Michael; Lamers Wouter H; Morano Ingo; Safak Erdal; Ahmed Asif; le Noble Ferdinand
Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism, intervention, and long-term consequences.
PloS one 2009;4(4):e5155.
2008: Fischer Christian; Mazzone Massimiliano; Jonckx Bart; Carmeliet Peter
FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?
Nature reviews. Cancer 2008;8(12):942-56.
2008: Fu Jianxin; Gerhardt Holger; McDaniel J Michael; Xia Baoyun; Liu Xiaowei; Ivanciu Lacramioara; Ny Annelii; Hermans Karlien; Silasi-Mansat Robert; McGee Samuel; Nye Emma; Ju Tongzhong; Ramirez Maria I; Carmeliet Peter; Cummings Richard D; Lupu Florea; Xia Lijun
Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice.
The Journal of clinical investigation 2008;118(11):3725-37.
2008: Freitas-Andrade Moises; Carmeliet Peter; Stanimirovic Danica B; Moreno Maria
VEGFR-2-mediated increased proliferation and survival in response to oxygen and glucose deprivation in PlGF knockout astrocytes.
Journal of neurochemistry 2008;107(3):756-67.
2008: Tjwa Marc; Janssens Stefan; Carmeliet Peter
Plasmin therapy enhances mobilization of HPCs after G-CSF.
Blood 2008;112(10):4048-50.
2008: Poesen Koen; Lambrechts Diether; Van Damme Philip; Dhondt Joke; Bender Florian; Frank Nicolas; Bogaert Elke; Claes Bart; Heylen Line; Verheyen An; Raes Katrien; Tjwa Marc; Eriksson Ulf; Shibuya Masabumi; Nuydens Rony; Van Den Bosch Ludo; Meert Theo; D'Hooge Rudi; Sendtner Michael; Robberecht Wim; Carmeliet Peter
Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(42):10451-9.
2008: Yano Kiichiro; Okada Yoshiaki; Beldi Guido; Shih Shou-Ching; Bodyak Natalya; Okada Hitomi; Kang Peter M; Luscinskas William; Robson Simon C; Carmeliet Peter; Karumanchi S Ananth; Aird William C
Elevated levels of placental growth factor represent an adaptive host response in sepsis.
The Journal of experimental medicine 2008;205(11):2623-31.
2008: Murakami Masahiro; Nguyen Loc T; Zhuang Zhen W; Moodie Karen L; Carmeliet Peter; Stan Radu V; Simons Michael
The FGF system has a key role in regulating vascular integrity.
The Journal of clinical investigation 2008;118(10):3355-66.
2008: Lutgens E; Tjwa M; Garcia de Frutos P; Wijnands E; Beckers L; Dahlbäck B; Daemen M J A P; Carmeliet P; Moons L
Genetic loss of Gas6 induces plaque stability in experimental atherosclerosis.
The Journal of pathology 2008;216(1):55-63.
2008: Li Xuri; Tjwa Marc; Van Hove Inge; Enholm Berndt; Neven Elke; Paavonen Karri; Jeltsch Michael; Juan Toni Diez; Sievers Richard E; Chorianopoulos Emmanuel; Wada Hiromichi; Vanwildemeersch Maarten; Noel Agnes; Foidart Jean-Michel; Springer Matthew L; von Degenfeld Georges; Dewerchin Mieke; Blau Helen M; Alitalo Kari; Eriksson Ulf; Carmeliet Peter; Moons Lieve
Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(9):1614-20.
2008: Ny Annelii; Koch Marta; Vandevelde Wouter; Schneider Martin; Fischer Christian; Diez-Juan Antonio; Neven Elke; Geudens Ilse; Maity Sunit; Moons Lieve; Plaisance Stéphane; Lambrechts Diether; Carmeliet Peter; Dewerchin Mieke
Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles.
Blood 2008;112(5):1740-9.
2008: Vidal Berta; Serrano Antonio L; Tjwa Marc; Suelves Mònica; Ardite Esther; De Mori Roberta; Baeza-Raja Bernat; Martínez de Lagrán María; Lafuste Peggy; Ruiz-Bonilla Vanessa; Jardí Mercè; Gherardi Romain; Christov Christo; Dierssen Mara; Carmeliet Peter; Degen Jay L; Dewerchin Mieke; Muñoz-Cánoves Pura
Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathway.
Genes & development 2008;22(13):1747-52.
2008: Mazzone Massimiliano; Carmeliet Peter
Drug discovery: a lifeline for suffocating tissues.
Nature 2008;453(7199):1194-5.
2008: Carmeliet Peter; Baes Myriam
Metabolism and therapeutic angiogenesis.
The New England journal of medicine 2008;358(23):2511-2.
2008: Binder Michele D; Cate Holly S; Prieto Anne L; Kemper Dennis; Butzkueven Helmut; Gresle Melissa M; Cipriani Tania; Jokubaitis Vilija G; Carmeliet Peter; Kilpatrick Trevor J
Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone-induced demyelination.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(20):5195-206.
2008: Rolny Charlotte; Capparuccia Lorena; Casazza Andrea; Mazzone Massimiliano; Vallario Antonella; Cignetti Alessandro; Medico Enzo; Carmeliet Peter; Comoglio Paolo M; Tamagnone Luca
The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment.
The Journal of experimental medicine 2008;205(5):1155-71.
2008: Bruyère Françoise; Melen-Lamalle Laurence; Blacher Silvia; Roland Guy; Thiry Marc; Moons Lieve; Frankenne Francis; Carmeliet Peter; Alitalo Kari; Libert Claude; Sleeman Jonathan P; Foidart Jean-Michel; Noël Agnès
Modeling lymphangiogenesis in a three-dimensional culture system.
Nature methods 2008;5(5):431-7.
2008: Bishop Tammie; Gallagher Denis; Pascual Alberto; Lygate Craig A; de Bono Joseph P; Nicholls Lynn G; Ortega-Saenz Patricia; Oster Henrik; Wijeyekoon Bhathiya; Sutherland Andrew I; Grosfeld Alexandra; Aragones Julian; Schneider Martin; van Geyte Katie; Teixeira Dania; Diez-Juan Antonio; Lopez-Barneo Jose; Channon Keith M; Maxwell Patrick H; Pugh Christopher W; Davies Alun M; Carmeliet Peter; Ratcliffe Peter J
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice.
Molecular and cellular biology 2008;28(10):3386-400.
2008: van den Akker Nynke M S; Caolo Vincenza; Wisse Lambertus J; Peters Patricia P W M; Poelmann Robert E; Carmeliet Peter; Molin Daniël G M; Gittenberger-de Groot Adriana C
Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.
Cardiovascular research 2008;78(2):366-75.
2008: Van Damme Philip; Van Hoecke Annelies; Lambrechts Diether; Vanacker Peter; Bogaert Elke; van Swieten John; Carmeliet Peter; Van Den Bosch Ludo; Robberecht Wim
Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival.
The Journal of cell biology 2008;181(1):37-41.
2008: Mikhaylova Olga; Ignacak Monika L; Barankiewicz Teresa J; Harbaugh Svetlana V; Yi Ying; Maxwell Patrick H; Schneider Martin; Van Geyte Katie; Carmeliet Peter; Revelo Monica P; Wyder Michael; Greis Kenneth D; Meller Jarek; Czyzyk-Krzeska Maria F
The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress.
Molecular and cellular biology 2008;28(8):2701-17.
2008: Renckens R; Roelofs J J T H; Stegenga M E; Florquin S; Levi M; Carmeliet P; Van't Veer C; van der Poll T
Transgenic tissue-type plasminogen activator expression improves host defense during Klebsiella pneumonia.
Journal of thrombosis and haemostasis : JTH 2008;6(4):660-8.
2008: Tjwa Marc; Bellido-Martin Lola; Lin Yuan; Lutgens Esther; Plaisance Stéphane; Bono Françoise; Delesque-Touchard Nathalie; Hervé Caroline; Moura Rute; Billiau An D; Aparicio Cristina; Levi Marcel; Daemen Mat; Dewerchin Mieke; Lupu Florea; Arnout Jef; Herbert Jean-Marc; Waer Mark; García de Frutos Pablo; Dahlbäck Björn; Carmeliet Peter; Hoylaerts Marc F; Moons Lieve
Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
Blood 2008;111(8):4096-105.
2008: Fraisl Peter; Baes Myriam; Carmeliet Peter
Hungry for blood vessels: linking metabolism and angiogenesis.
Developmental cell 2008;14(3):313-4.
2008: Zacchigna Serena; Lambrechts Diether; Carmeliet Peter
Neurovascular signalling defects in neurodegeneration.
Nature reviews. Neuroscience 2008;9(3):169-81.
2008: Li Lizhen; Lundkvist Andrea; Andersson Daniel; Wilhelmsson Ulrika; Nagai Nobuo; Pardo Andrea C; Nodin Christina; Ståhlberg Anders; Aprico Karina; Larsson Kerstin; Yabe Takeshi; Moons Lieve; Fotheringham Andrew; Davies Ioan; Carmeliet Peter; Schwartz Joan P; Pekna Marcela; Kubista Mikael; Blomstrand Fredrik; Maragakis Nicholas; Nilsson Michael; Pekny Milos
Protective role of reactive astrocytes in brain ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(3):468-81.
2008: Angelillo-Scherrer Anne; Burnier Laurent; Lambrechts Diether; Fish Richard J; Tjwa Marc; Plaisance Stéphane; Sugamele Rocco; DeMol Maria; Martinez-Soria Eduardo; Maxwell Patrick H; Lemke Greg; Goff Stephen P; Matsushima Glenn K; Earp H Shelton; Chanson Marc; Collen Désiré; Izui Shozo; Schapira Marc; Conway Edward M; Carmeliet Peter
Role of Gas6 in erythropoiesis and anemia in mice.
The Journal of clinical investigation 2008;118(2):583-96.
2008: Hill Peter; Shukla Deepa; Tran Maxine G B; Aragones Julian; Cook H Terence; Carmeliet Peter; Maxwell Patrick H
Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury.
Journal of the American Society of Nephrology : JASN 2008;19(1):39-46.
2008: Wei Changli; Möller Clemens C; Altintas Mehmet M; Li Jing; Schwarz Karin; Zacchigna Serena; Xie Liang; Henger Anna; Schmid Holger; Rastaldi Maria P; Cowan Peter; Kretzler Matthias; Parrilla Roberto; Bendayan Moïse; Gupta Vineet; Nikolic Boris; Kalluri Raghu; Carmeliet Peter; Mundel Peter; Reiser Jochen
Modification of kidney barrier function by the urokinase receptor.
Nature medicine 2008;14(1):55-63.
2008: Zacchigna Serena; Ruiz de Almodovar Carmen; Carmeliet Peter
Similarities between angiogenesis and neural development: what small animal models can tell us.
Current topics in developmental biology 2008;80():1-55.
2007: Esguerra Camila V; Nelles Luc; Vermeire Liesbeth; Ibrahimi Abdelilah; Crawford Alexander D; Derua Rita; Janssens Els; Waelkens Etienne; Carmeliet Peter; Collen Desiré; Huylebroeck Danny
Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination.
Development (Cambridge, England) 2007;134(24):4381-93.
2007: Tugues Sònia; Fernandez-Varo Guillermo; Muñoz-Luque Javier; Ros Josefa; Arroyo Vicente; Rodés Juan; Friedman Scott L; Carmeliet Peter; Jiménez Wladimiro; Morales-Ruiz Manuel
Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats.
Hepatology (Baltimore, Md.) 2007;46(6):1919-26.
2007: Fischer Christian; Jonckx Bart; Mazzone Massimiliano; Zacchigna Serena; Loges Sonja; Pattarini Lucia; Chorianopoulos Emmanuel; Liesenborghs Laurens; Koch Marta; De Mol Maria; Autiero Monica; Wyns Sabine; Plaisance Stephane; Moons Lieve; van Rooijen Nico; Giacca Mauro; Stassen Jean-Marie; Dewerchin Mieke; Collen Desire; Carmeliet Peter
Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels.
Cell 2007;131(3):463-75.
2007: Tirziu Daniela; Chorianopoulos Emmanuel; Moodie Karen L; Palac Robert T; Zhuang Zhen W; Tjwa Marc; Roncal Carmen; Eriksson Ulf; Fu Qiangwei; Elfenbein Arye; Hall Amy E; Carmeliet Peter; Moons Lieve; Simons Michael
Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice.
The Journal of clinical investigation 2007;117(11):3188-97.
2007: Mazzone Massimiliano; Ruiz de Almodovar Carmen; Carmeliet Peter
Building in resistance to endothelial cell death.
Nature genetics 2007;39(11):1308-9.
2007: Larrivée Bruno; Freitas Catarina; Trombe Marc; Lv Xiang; Delafarge Benjamin; Yuan Li; Bouvrée Karine; Bréant Christiane; Del Toro Raquel; Bréchot Nicolas; Germain Stéphane; Bono Françoise; Dol Frédérique; Claes Filip; Fischer Christian; Autiero Monica; Thomas Jean-Léon; Carmeliet Peter; Tessier-Lavigne Marc; Eichmann Anne
Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis.
Genes & development 2007;21(19):2433-47.
2007: Lambrechts Diether; Robberecht Wim; Carmeliet Peter
Heterogeneity in motoneuron disease.
Trends in neurosciences 2007;30(10):536-44.
2007: Jost Maud; Maillard Catherine; Lecomte Julie; Lambert Vincent; Tjwa Marc; Blaise Pierre; Alvarez Gonzalez Maria-Luz; Bajou Khalid; Blacher Silvia; Motte Patrick; Humblet Chantal; Defresne Marie Paule; Thiry Marc; Frankenne Francis; Gothot André; Carmeliet Peter; Rakic Jean-Marie; Foidart Jean-Michel; Noël Agnès
Tumoral and choroidal vascularization: differential cellular mechanisms involving plasminogen activator inhibitor type I.
The American journal of pathology 2007;171(4):1369-80.
2007: Lemmens Robin; Van Hoecke Annelies; Hersmus Nicole; Geelen Veerle; D'Hollander Isabel; Thijs Vincent; Van Den Bosch Ludo; Carmeliet Peter; Robberecht Wim
Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish.
Human molecular genetics 2007;16(19):2359-65.
2007: Van Damme Philip; Bogaert Elke; Dewil Maarten; Hersmus Nicole; Kiraly Dora; Scheveneels Wendy; Bockx Ilse; Braeken Dries; Verpoorten Nathalie; Verhoeven Kristien; Timmerman Vincent; Herijgers Paul; Callewaert Geert; Carmeliet Peter; Van Den Bosch Ludo; Robberecht Wim
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(37):14825-30.
2007: Suelves Mònica; Vidal Berta; Serrano Antonio L; Tjwa Marc; Roma Josep; López-Alemany Roser; Luttun Aernout; de Lagrán María Martínez; Díaz-Ramos Angels; Jardí Mercè; Roig Manuel; Dierssen Mara; Dewerchin Mieke; Carmeliet Peter; Muñoz-Cánoves Pura
uPA deficiency exacerbates muscular dystrophy in MDX mice.
The Journal of cell biology 2007;178(6):1039-51.
2007: Sonoda Koh-Hei; Nakamura Takahiko; Young Howard A; Hart David; Carmeliet Peter; Stein-Streilein Joan
NKT cell-derived urokinase-type plasminogen activator promotes peripheral tolerance associated with eye.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2215-22.
2007: Cacquevel Mathias; Launay Séverine; Castel Hervé; Benchenane Karim; Chéenne Simon; Buée Luc; Moons Lieve; Delacourte André; Carmeliet Peter; Vivien Denis
Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms.
Neurobiology of disease 2007;27(2):164-73.
2007: Buysschaert I; Carmeliet P; Dewerchin M
Clinical and fundamental aspects of angiogenesis and anti-angiogenesis.
Acta clinica Belgica 2007;62(3):162-9.
2007: Leroux P; Hennebert O; Legros H; Laudenbach V; Carmeliet P; Marret S
Role of tissue-plasminogen activator (t-PA) in a mouse model of neonatal white matter lesions: interaction with plasmin inhibitors and anti-inflammatory drugs.
Neuroscience 2007;146(2):670-8.
2007: Tayade Chandrakant; Hilchie David; He Hong; Fang Yuan; Moons Lieve; Carmeliet Peter; Foster Robert A; Croy B Anne
Genetic deletion of placenta growth factor in mice alters uterine NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4267-75.
2007: Laudenbach Vincent; Fontaine Romain H; Medja Fadia; Carmeliet Peter; Hicklin Daniel J; Gallego Jorge; Leroux Philippe; Marret Stéphane; Gressens Pierre
Neonatal hypoxic preconditioning involves vascular endothelial growth factor.
Neurobiology of disease 2007;26(1):243-52.
2007: van den Akker Nynke M S; Molin Daniël G M; Peters Patricia P W M; Maas Saskia; Wisse Lambertus J; van Brempt Ronald; van Munsteren Conny J; Bartelings Margot M; Poelmann Robert E; Carmeliet Peter; Gittenberger-de Groot Adriana C
Tetralogy of fallot and alterations in vascular endothelial growth factor-A signaling and notch signaling in mouse embryos solely expressing the VEGF120 isoform.
Circulation research 2007;100(6):842-9.
2007: Renckens Rosemarijn; Roelofs Joris J T H; Bonta Peter I; Florquin Sandrine; de Vries Carlie J M; Levi Marcel; Carmeliet Peter; van't Veer Cornelis; van der Poll Tom
Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia.
Blood 2007;109(4):1593-601.
2007: Vanhoutte Davy; Schellings Mark W M; Götte Martin; Swinnen Melissa; Herias Veronica; Wild Martin K; Vestweber Dietmar; Chorianopoulos Emmanuel; Cortés Víctor; Rigotti Attilio; Stepp Mary-Ann; Van de Werf Frans; Carmeliet Peter; Pinto Yigal M; Heymans Stephane
Increased expression of syndecan-1 protects against cardiac dilatation and dysfunction after myocardial infarction.
Circulation 2007;115(4):475-82.
2007: Giacobini Paolo; Messina Andrea; Wray Susan; Giampietro Costanza; Crepaldi Tiziana; Carmeliet Peter; Fasolo Aldo
Hepatocyte growth factor acts as a motogen and guidance signal for gonadotropin hormone-releasing hormone-1 neuronal migration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(2):431-45.
2006: Remme Carol Ann; Verkerk Arie O; Nuyens Dieter; van Ginneken Antoni C G; van Brunschot Sandra; Belterman Charly N W; Wilders Ronald; van Roon Marian A; Tan Hanno L; Wilde Arthur A M; Carmeliet Peter; de Bakker Jacques M T; Veldkamp Marieke W; Bezzina Connie R
Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD.
Circulation 2006;114(24):2584-94.
2006: Masuyama Ritsuko; Stockmans Ingrid; Torrekens Sophie; Van Looveren Riet; Maes Christa; Carmeliet Peter; Bouillon Roger; Carmeliet Geert
Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts.
The Journal of clinical investigation 2006;116(12):3150-9.
2006: Fredj Sandra; Lindegger Nicolas; Sampson Kevin J; Carmeliet Peter; Kass Robert S
Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytes.
Circulation research 2006;99(11):1225-32.
2006: Lambrechts Diether; Carmeliet Peter
VEGF at the neurovascular interface: therapeutic implications for motor neuron disease.
Biochimica et biophysica acta 2006;1762(11-12):1109-21.
2006: Lijnen H Roger; Christiaens Valerie; Scroyen Ilse; Voros Gabor; Tjwa Marc; Carmeliet Peter; Collen Désiré
Impaired adipose tissue development in mice with inactivation of placental growth factor function.
Diabetes 2006;55(10):2698-704.
2006: He Yun; Luo Yan; Tang Shibo; Rajantie Iiro; Salven Petri; Heil Matthias; Zhang Rong; Luo Dianhong; Li Xianghong; Chi Hongbo; Yu Jun; Carmeliet Peter; Schaper Wolfgang; Sinusas Albert J; Sessa William C; Alitalo Kari; Min Wang
Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis.
The Journal of clinical investigation 2006;116(9):2344-55.
2006: Heymans Stephane; Pauschinger Matthias; De Palma Armando; Kallwellis-Opara Angela; Rutschow Susanne; Swinnen Melissa; Vanhoutte Davy; Gao Fangye; Torpai Raimund; Baker Andrew H; Padalko Elisabeth; Neyts Johan; Schultheiss Heinz-Peter; Van de Werf Frans; Carmeliet Peter; Pinto Yigal M
Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis.
Circulation 2006;114(6):565-73.
2006: Lambrechts Diether; Lafuste Peggy; Carmeliet Peter; Conway Edward M
Another angiogenic gene linked to amyotrophic lateral sclerosis.
Trends in molecular medicine 2006;12(8):345-7.
2006: Cochran David M; Fukumura Dai; Ancukiewicz Marek; Carmeliet Peter; Jain Rakesh K
Evolution of oxygen and glucose concentration profiles in a tissue-mimetic culture system of embryonic stem cells.
Annals of biomedical engineering 2006;34(8):1247-58.
2006: Vangheluwe Peter; Tjwa Marc; Van Den Bergh An; Louch William E; Beullens Monique; Dode Leonard; Carmeliet Peter; Kranias Evangelia; Herijgers Paul; Sipido Karin R; Raeymaekers Luc; Wuytack Frank
A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span.
Journal of molecular and cellular cardiology 2006;41(2):308-17.
2006: Schneider Martin; Ny Annelii; Ruiz de Almodovar Carmen; Carmeliet Peter
A new mouse model to study acquired lymphedema.
PLoS medicine 2006;3(7):e264.
2006: Fischer Christian; Carmeliet Peter; Conway Edward M
VEGF inhibitors make blood.
Nature medicine 2006;12(7):732-4.
2006: Renckens Rosemarijn; Roelofs Joris J T H; Florquin Sandrine; de Vos Alex F; Pater Jennie M; Lijnen H Roger; Carmeliet Peter; van 't Veer Cornelis; van der Poll Tom
Endogenous tissue-type plasminogen activator is protective during Escherichia coli-induced abdominal sepsis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1189-96.
2006: Li Bin; Sharpe Emerson E; Maupin Amanda B; Teleron Amylynn A; Pyle Amy L; Carmeliet Peter; Young Pampee P
VEGF and PlGF promote adult vasculogenesis by enhancing EPC recruitment and vessel formation at the site of tumor neovascularization.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(9):1495-7.
2006: Chittenden Thomas W; Claes Filip; Lanahan Anthony A; Autiero Monica; Palac Robert T; Tkachenko Eugene V; Elfenbein Arye; Ruiz de Almodovar Carmen; Dedkov Eduard; Tomanek Robert; Li Weiming; Westmore Michael; Singh Jai Pal; Horowitz Arie; Mulligan-Kehoe Mary Jo; Moodie Karen L; Zhuang Zhen W; Carmeliet Peter; Simons Michael
Selective regulation of arterial branching morphogenesis by synectin.
Developmental cell 2006;10(6):783-95.
2006: Yano Kiichiro; Liaw Patricia C; Mullington Janet M; Shih Shu-Ching; Okada Hitomi; Bodyak Natalya; Kang Peter M; Toltl Lisa; Belikoff Bryan; Buras Jon; Simms Benjamin T; Mizgerd Joseph P; Carmeliet Peter; Karumanchi S Ananth; Aird William C
Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality.
The Journal of experimental medicine 2006;203(6):1447-58.
2006: Aerts Stein; Lambrechts Diether; Maity Sunit; Van Loo Peter; Coessens Bert; De Smet Frederik; Tranchevent Leon-Charles; De Moor Bart; Marynen Peter; Hassan Bassem; Carmeliet Peter; Moreau Yves
Gene prioritization through genomic data fusion.
Nature biotechnology 2006;24(5):537-44.
2006: De Smet Frederik; Carmeliet Peter; Autiero Monica
Fishing and frogging for anti-angiogenic drugs.
Nature chemical biology 2006;2(5):228-9.
2006: Maes Christa; Coenegrachts Lieve; Stockmans Ingrid; Daci Evis; Luttun Aernout; Petryk Anna; Gopalakrishnan Rajaram; Moermans Karen; Smets Nico; Verfaillie Catherine M; Carmeliet Peter; Bouillon Roger; Carmeliet Geert
Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair.
The Journal of clinical investigation 2006;116(5):1230-42.
2006: Tjwa Marc; Carmeliet Peter; Moons Lieve
Novel transgenic rabbit model sheds light on the puzzling role of matrix metalloproteinase-12 in atherosclerosis.
Circulation 2006;113(16):1929-32.
2006: Le Bras Barbara; Barallobre Maria-José; Homman-Ludiye Jihane; Ny Annelii; Wyns Sabine; Tammela Tuomas; Haiko Paula; Karkkainen Marika J; Yuan Li; Muriel Marie-Paule; Chatzopoulou Elli; Bréant Christiane; Zalc Bernard; Carmeliet Peter; Alitalo Kari; Eichmann Anne; Thomas Jean-Léon
VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain.
Nature neuroscience 2006;9(3):340-8.
2006: Rossignol P; Luttun A; Martin-Ventura J L; Lupu F; Carmeliet P; Collen D; Anglès-Cano E; Lijnen H R
Plasminogen activation: a mediator of vascular smooth muscle cell apoptosis in atherosclerotic plaques.
Journal of thrombosis and haemostasis : JTH 2006;4(3):664-70.
2006: Alva Jackelyn A; Zovein Ann C; Monvoisin Arnaud; Murphy Thomas; Salazar Anthony; Harvey Natasha L; Carmeliet Peter; Iruela-Arispe M Luisa
VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells.
Developmental dynamics : an official publication of the American Association of Anatomists 2006;235(3):759-67.
2006: Ny Annelii; Autiero Monica; Carmeliet Peter
Zebrafish and Xenopus tadpoles: small animal models to study angiogenesis and lymphangiogenesis.
Experimental cell research 2006;312(5):684-93.
2006: Vinores Stanley A; Xiao Wei-Hong; Aslam Sadia; Shen Jikui; Oshima Yuji; Nambu Hiroyuki; Liu Hansheng; Carmeliet Peter; Campochiaro Peter A
Implication of the hypoxia response element of the Vegf promoter in mouse models of retinal and choroidal neovascularization, but not retinal vascular development.
Journal of cellular physiology 2006;206(3):749-58.
2006: Ruiz de Almodovar Carmen; Luttun Aernout; Carmeliet Peter
An SDF-1 trap for myeloid cells stimulates angiogenesis.
Cell 2006;124(1):18-21.
2006: Fischer C; Schneider M; Carmeliet P
Principles and therapeutic implications of angiogenesis, vasculogenesis and arteriogenesis.
Handbook of experimental pharmacology 2006;(176 Pt 2):157-212.
2005: Roy Himadri; Bhardwaj Shalini; Babu Mohan; Jauhiainen Suvi; Herzig Karl-Heinz; Bellu Anna R; Haisma Hidde J; Carmeliet Peter; Alitalo Kari; Ylä-Herttuala Seppo
Adenovirus-mediated gene transfer of placental growth factor to perivascular tissue induces angiogenesis via upregulation of the expression of endogenous vascular endothelial growth factor-A.
Human gene therapy 2005;16(12):1422-8.
2005: Carmeliet Peter
Angiogenesis in life, disease and medicine.
Nature 2005;438(7070):932-6.
2005: Krag Søren; Danielsen Carl Christian; Carmeliet Peter; Nyengaard Jens; Wogensen Lise
Plasminogen activator inhibitor-1 gene deficiency attenuates TGF-beta1-induced kidney disease.
Kidney international 2005;68(6):2651-66.
2005: Cowden Dahl Karen D; Fryer Benjamin H; Mack Fiona A; Compernolle Veerle; Maltepe Emin; Adelman David M; Carmeliet Peter; Simon M Celeste
Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation.
Molecular and cellular biology 2005;25(23):10479-91.
2005: Schneider Martin; Conway Edward M; Carmeliet Peter
Lymph makes you fat.
Nature genetics 2005;37(10):1023-4.
2005: de Giorgio-Miller Alexander; Bottoms Steve; Laurent Geoffrey; Carmeliet Peter; Herrick Sarah
Fibrin-induced skin fibrosis in mice deficient in tissue plasminogen activator.
The American journal of pathology 2005;167(3):721-32.
2005: Ny Annelii; Koch Marta; Schneider Martin; Neven Elke; Tong Ricky T; Maity Sunit; Fischer Christian; Plaisance Stephane; Lambrechts Diether; Héligon Christophe; Terclavers Sven; Ciesiolka Malgorzata; Kälin Roland; Man Wing Yan; Senn Irena; Wyns Sabine; Lupu Florea; Brändli André; Vleminckx Kris; Collen Désiré; Dewerchin Mieke; Conway Edward M; Moons Lieve; Jain Rakesh K; Carmeliet Peter
A genetic Xenopus laevis tadpole model to study lymphangiogenesis.
Nature medicine 2005;11(9):998-1004.
2005: Heymans Stephane; Schroen Blanche; Vermeersch Pieter; Milting Hendrik; Gao Fangye; Kassner Astrid; Gillijns Hilde; Herijgers Paul; Flameng Willem; Carmeliet Peter; Van de Werf Frans; Pinto Yigal M; Janssens Stefan
Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart.
Circulation 2005;112(8):1136-44.
2005: Acker Till; Diez-Juan Antonio; Aragones Julian; Tjwa Marc; Brusselmans Koen; Moons Lieve; Fukumura Dai; Moreno-Murciano Maria Paz; Herbert Jean-Marc; Burger Angelika; Riedel Johanna; Elvert Gerd; Flamme Ingo; Maxwell Patrick H; Collen Désiré; Dewerchin Mieke; Jain Rakesh K; Plate Karl H; Carmeliet Peter
Genetic evidence for a tumor suppressor role of HIF-2alpha.
Cancer cell 2005;8(2):131-41.
2005: Ott Ilka; Michaelis Cornelia; Schuermann Maren; Steppich Birgit; Seitz Isabell; Dewerchin Mieke; Zohlnhofer Dietlind; Wessely Rainer; Rudelius Martina; Schömig Albert; Carmeliet Peter
Vascular remodeling in mice lacking the cytoplasmic domain of tissue factor.
Circulation research 2005;97(3):293-8.
2005: Müller Susanna M; Terszowski Grzegorz; Blum Carmen; Haller Corinne; Anquez Viviane; Kuschert Stephen; Carmeliet Peter; Augustin Hellmut G; Rodewald Hans-Reimer
Gene targeting of VEGF-A in thymus epithelium disrupts thymus blood vessel architecture.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(30):10587-92.
2005: Carmeliet Peter; Tessier-Lavigne Marc
Common mechanisms of nerve and blood vessel wiring.
Nature 2005;436(7048):193-200.
2005: Melis Els; Moons Lieve; Arnout Jef; Hoylaerts Marc F; Collen Désiré; Carmeliet Peter; Dewerchin Mieke
Thrombophilia in mice expressing a tissue factor variant lacking its transmembrane and cytosolic domain.
Biochemical and biophysical research communications 2005;333(2):488-95.
2005: Zanetta Lucia; Corada Monica; Grazia Lampugnani Maria; Zanetti Adriana; Breviario Ferruccio; Moons Lieve; Carmeliet Peter; Pepper Michael S; Dejana Elisabetta
Downregulation of vascular endothelial-cadherin expression is associated with an increase in vascular tumor growth and hemorrhagic complications.
Thrombosis and haemostasis 2005;93(6):1041-6.
2005: Khurana Rohit; Moons Lieve; Shafi Shahida; Luttun Aernout; Collen Désiré; Martin John F; Carmeliet Peter; Zachary Ian C
Placental growth factor promotes atherosclerotic intimal thickening and macrophage accumulation.
Circulation 2005;111(21):2828-36.
2005: Renckens R; Roelofs J J T H; de Waard V; Florquin S; Lijnen H R; Carmeliet P; van der Poll T
The role of plasminogen activator inhibitor type 1 in the inflammatory response to local tissue injury.
Journal of thrombosis and haemostasis : JTH 2005;3(5):1018-25.
2005: Rossenbacker T; Schollen E; Kuipéri C; de Ravel T J L; Devriendt K; Matthijs G; Collen D; Heidbüchel H; Carmeliet P
Unconventional intronic splice site mutation in SCN5A associates with cardiac sodium channelopathy.
Journal of medical genetics 2005;42(5):e29.
2005: Maquoi Erik; Vörös Gabor; Carmeliet Peter; Collen Désiré; Lijnen H Roger
Role of Gas-6 in adipogenesis and nutritionally induced adipose tissue development in mice.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(5):1002-7.
2005: Taylor Michael R; Kikkawa Satoshi; Diez-Juan Antonio; Ramamurthy Visvanathan; Kawakami Koichi; Carmeliet Peter; Brockerhoff Susan E
The zebrafish pob gene encodes a novel protein required for survival of red cone photoreceptor cells.
Genetics 2005;170(1):263-73.
2005: Rossenbacker Tom; Mubagwa Kanigula; Jongbloed Roselie J; Vereecke Johan; Devriendt Koen; Gewillig Marc; Carmeliet Edward; Collen Désiré; Heidbüchel Hein; Carmeliet Peter
Novel mutation in the Per-Arnt-Sim domain of KCNH2 causes a malignant form of long-QT syndrome.
Circulation 2005;111(8):961-8.
2005: Eichmann Anne; Le Noble Ferdinand; Autiero Monica; Carmeliet Peter
Guidance of vascular and neural network formation.
Current opinion in neurobiology 2005;15(1):108-15.
2005: Autiero Monica; De Smet Frederik; Claes Filip; Carmeliet Peter
Role of neural guidance signals in blood vessel navigation.
Cardiovascular research 2005;65(3):629-38.
2005: Angelillo-Scherrer Anne; Burnier Laurent; Flores Nathalie; Savi Pierre; DeMol Maria; Schaeffer Paul; Herbert Jean-Marc; Lemke Greg; Goff Stephen P; Matsushima Glenn K; Earp H Shelton; Vesin Christian; Hoylaerts Marc F; Plaisance Stéphane; Collen Désiré; Conway Edward M; Wehrle-Haller Bernhard; Carmeliet Peter
Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.
The Journal of clinical investigation 2005;115(2):237-46.
2005: Brusselmans Koen; Bono Françoise; Collen Désiré; Herbert Jean-Marc; Carmeliet Peter; Dewerchin Mieke
A novel role for vascular endothelial growth factor as an autocrine survival factor for embryonic stem cells during hypoxia.
The Journal of biological chemistry 2005;280(5):3493-9.
2005: Maillard Catherine; Jost Maud; Rømer Maria Unni; Brunner Nils; Houard Xavier; Lejeune Annabelle; Munaut Carine; Bajou Khalid; Melen Laurence; Dano Keld; Carmeliet Peter; Fusenig Norbert E; Foidart Jean Michel; Noel Agnès
Host plasminogen activator inhibitor-1 promotes human skin carcinoma progression in a stage-dependent manner.
Neoplasia (New York, N.Y.) 2005;7(1):57-66.
2005: Kryczek Ilona; Lange Andrzej; Mottram Peter; Alvarez Xavier; Cheng Pui; Hogan Melina; Moons Lieve; Wei Shuang; Zou Linhua; Machelon Véronique; Emilie Dominique; Terrassa Margarita; Lackner Andrew; Curiel Tyler J; Carmeliet Peter; Zou Weiping
CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers.
Cancer research 2005;65(2):465-72.
2005: Schneider Martin; Tjwa Marc; Carmeliet Peter
A surrogate marker to monitor angiogenesis at last.
Cancer cell 2005;7(1):3-4.
2005: Heymans Stephane; Lupu Florea; Terclavers Sven; Vanwetswinkel Bjorn; Herbert Jean-Marc; Baker Andrew; Collen Desire; Carmeliet Peter; Moons Lieve
Loss or inhibition of uPA or MMP-9 attenuates LV remodeling and dysfunction after acute pressure overload in mice.
The American journal of pathology 2005;166(1):15-25.
2005: Li Xuri; Tjwa Marc; Moons Lieve; Fons Pierre; Noel Agnes; Ny Annelii; Zhou Jian Min; Lennartsson Johan; Li Hong; Luttun Aernout; Pontén Annica; Devy Laetitia; Bouché Ann; Oh Hideyasu; Manderveld Ann; Blacher Silvia; Communi David; Savi Pierre; Bono Françoise; Dewerchin Mieke; Foidart Jean-Michel; Autiero Monica; Herbert Jean-Marc; Collen D; Heldin Carl-Henrik; Eriksson Ulf; Carmeliet Peter
Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors.
The Journal of clinical investigation 2005;115(1):118-27.
2005: Krücken Jürgen; Dkhil Mohamed A; Braun Juliane V; Schroetel Regina M U; El-Khadragy Manal; Carmeliet Peter; Mossmann Horst; Wunderlich Frank
Testosterone suppresses protective responses of the liver to blood-stage malaria.
Infection and immunity 2005;73(1):436-43.
2005: Storkebaum Erik; Lambrechts Diether; Dewerchin Mieke; Moreno-Murciano Maria-Paz; Appelmans Saskia; Oh Hideyasu; Van Damme Philip; Rutten Bart; Man Wing Yan; De Mol Maria; Wyns Sabine; Manka David; Vermeulen Kristel; Van Den Bosch Ludo; Mertens Nico; Schmitz Christoph; Robberecht Wim; Conway Edward M; Collen Désiré; Moons Lieve; Carmeliet Peter
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.
Nature neuroscience 2005;8(1):85-92.
2005: Carmeliet Peter
VEGF as a key mediator of angiogenesis in cancer.
Oncology 2005;69 Suppl 3():4-10.
2005: Hennebert O; Laudenbach V; Laquerriere A; Verney C; Carmeliet P; Marret S; Leroux P
Ontogenic study of the influence of tissue plasminogen activator (t-PA) in neonatal excitotoxic brain insult and the subsequent microglia/macrophage activation.
Neuroscience 2005;130(3):697-712.
2004: Rossenbacker Tom; Carroll Sheila J; Liu Huajun; Kuipéri Cuno; de Ravel Thomy J L; Devriendt Koen; Carmeliet Peter; Kass Robert S; Heidbüchel Hein
Novel pore mutation in SCN5A manifests as a spectrum of phenotypes ranging from atrial flutter, conduction disease, and Brugada syndrome to sudden cardiac death.
Heart rhythm : the official journal of the Heart Rhythm Society 2004;1(5):610-5.
2004: Lu Xiaowei; Le Noble Ferdinand; Yuan Li; Jiang Quingjan; De Lafarge Benjamin; Sugiyama Daisuke; Bréant Christiane; Claes Filip; De Smet Frederik; Thomas Jean-Léon; Autiero Monica; Carmeliet Peter; Tessier-Lavigne Marc; Eichmann Anne
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system.
Nature 2004;432(7014):179-86.
2004: Alam Antoine; Herault Jean-Pascal; Barron Pauline; Favier Benoit; Fons Pierre; Delesque-Touchard Nathalie; Senegas Isabelle; Laboudie Patricia; Bonnin Jacques; Cassan Cecile; Savi Pierre; Ruggeri Bruce; Carmeliet Peter; Bono Françoise; Herbert Jean-Marc
Heterodimerization with vascular endothelial growth factor receptor-2 (VEGFR-2) is necessary for VEGFR-3 activity.
Biochemical and biophysical research communications 2004;324(2):909-15.
2004: Molinas Carlos Roger; Binda Maria Merces; Carmeliet Peter; Koninckx Philippe Robert
Role of vascular endothelial growth factor receptor 1 in basal adhesion formation and in carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in mice.
Fertility and sterility 2004;82 Suppl 3():1149-53.
2004: Van Den Bosch Ludo; Storkebaum Erik; Vleminckx Vicky; Moons Lieve; Vanopdenbosch Ludo; Scheveneels Wendy; Carmeliet Peter; Robberecht Wim
Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration.
Neurobiology of disease 2004;17(1):21-8.
2004: Storkebaum Erik; Lambrechts Diether; Carmeliet Peter
VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection.
BioEssays : news and reviews in molecular, cellular and developmental biology 2004;26(9):943-54.
2004: Lambrechts Diether; Carmeliet Peter
Sculpting heart valves with NFATc and VEGF.
Cell 2004;118(5):532-4.
2004: Bajou Khalid; Maillard Catherine; Jost Maud; Lijnen Roger H; Gils Ann; Declerck Paul; Carmeliet Peter; Foidart Jean-Michel; Noel Agnès
Host-derived plasminogen activator inhibitor-1 (PAI-1) concentration is critical for in vivo tumoral angiogenesis and growth.
Oncogene 2004;23(41):6986-90.
2004: Curiel Tyler J; Cheng Pui; Mottram Peter; Alvarez Xavier; Moons Lieve; Evdemon-Hogan Melina; Wei Shuang; Zou Linhua; Kryczek Ilona; Hoyle Gary; Lackner Andrew; Carmeliet Peter; Zou Weiping
Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer.
Cancer research 2004;64(16):5535-8.
2004: Luttun Aernout; Carmeliet Peter
Angiogenesis and lymphangiogenesis: highlights of the past year.
Current opinion in hematology 2004;11(4):262-71.
2004: Lundkvist Andrea; Reichenbach Andreas; Betsholtz Christer; Carmeliet Peter; Wolburg Hartwig; Pekny Milos
Under stress, the absence of intermediate filaments from Müller cells in the retina has structural and functional consequences.
Journal of cell science 2004;117(Pt 16):3481-8.
2004: Sharma Laveena; Melis Els; Hickey Michael J; Clyne Colin D; Erlich Jonathan; Khachigian Levon M; Davenport Piers; Morand Eric; Carmeliet Peter; Tipping Peter G
The cytoplasmic domain of tissue factor contributes to leukocyte recruitment and death in endotoxemia.
The American journal of pathology 2004;165(1):331-40.
2004: Edgtton Kristy L; Gow Renae M; Kelly Darren J; Carmeliet Peter; Kitching A Richard
Plasmin is not protective in experimental renal interstitial fibrosis.
Kidney international 2004;66(1):68-76.
2004: Van Eynde Aleyde; Nuytten Mieke; Dewerchin Mieke; Schoonjans Luc; Keppens Stefaan; Beullens Monique; Moons Lieve; Carmeliet Peter; Stalmans Willy; Bollen Mathieu
The nuclear scaffold protein NIPP1 is essential for early embryonic development and cell proliferation.
Molecular and cellular biology 2004;24(13):5863-74.
2004: Lambrechts Diether; Storkebaum Erik; Carmeliet Peter
VEGF: necessary to prevent motoneuron degeneration, sufficient to treat ALS?
Trends in molecular medicine 2004;10(6):275-82.
2004: Azzouz Mimoun; Ralph G Scott; Storkebaum Erik; Walmsley Lucy E; Mitrophanous Kyriacos A; Kingsman Susan M; Carmeliet Peter; Mazarakis Nicholas D
VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model.
Nature 2004;429(6990):413-7.
2004: Belting Mattias; Dorrell Michael I; Sandgren Staffan; Aguilar Edith; Ahamed Jasimuddin; Dorfleutner Andrea; Carmeliet Peter; Mueller Barbara M; Friedlander Martin; Ruf Wolfram
Regulation of angiogenesis by tissue factor cytoplasmic domain signaling.
Nature medicine 2004;10(5):502-9.
2004: Carmeliet Peter
Manipulating angiogenesis in medicine.
Journal of internal medicine 2004;255(5):538-61.
2004: Luttun Aernout; Lutgens Esther; Manderveld Ann; Maris Katleen; Collen Désiré; Carmeliet Peter; Moons Lieve
Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against atherosclerotic media destruction but differentially affects plaque growth.
Circulation 2004;109(11):1408-14.
2004: Luttun Aernout; Autiero Monica; Tjwa Marc; Carmeliet Peter
Genetic dissection of tumor angiogenesis: are PlGF and VEGFR-1 novel anti-cancer targets?
Biochimica et biophysica acta 2004;1654(1):79-94.
2004: Lambrechts Diether; Carmeliet Peter
Medicine: genetic spotlight on a blood defect.
Nature 2004;427(6975):592-4.
2004: De Gendt Karel; Swinnen Johannes V; Saunders Philippa T K; Schoonjans Luc; Dewerchin Mieke; Devos Ann; Tan Karen; Atanassova Nina; Claessens Frank; Lécureuil Charlotte; Heyns Walter; Carmeliet Peter; Guillou Florian; Sharpe Richard M; Verhoeven Guido
A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1327-32.
2004: Hennebert Olivier; Marret Stéphane; Carmeliet Peter; Gressens Pierre; Laquerrière Annie; Leroux Philippe
Role of tissue-derived plasminogen activator (t-PA) in an excitotoxic mouse model of neonatal white matter lesions.
Journal of neuropathology and experimental neurology 2004;63(1):53-63.
2004: Maes Christa; Stockmans Ingrid; Moermans Karen; Van Looveren Riet; Smets Nico; Carmeliet Peter; Bouillon Roger; Carmeliet Geert
Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival.
The Journal of clinical investigation 2004;113(2):188-99.
2004: Storkebaum Erik; Carmeliet Peter
VEGF: a critical player in neurodegeneration.
The Journal of clinical investigation 2004;113(1):14-8.
2004: Yang Yuan H; Hall Pam; Milenkovski Georgia; Sharma Laveena; Hutchinson Paul; Melis Els; Carmeliet Peter; Tipping Peter; Morand Eric
Reduction in arthritis severity and modulation of immune function in tissue factor cytoplasmic domain mutant mice.
The American journal of pathology 2004;164(1):109-17.
2004: Padalko Elizaveta; Nuyens Dieter; De Palma Armando; Verbeken Erik; Aerts Joeri L; De Clercq Erik; Carmeliet Peter; Neyts Johan
The interferon inducer ampligen [poly(I)-poly(C12U)] markedly protects mice against coxsackie B3 virus-induced myocarditis.
Antimicrobial agents and chemotherapy 2004;48(1):267-74.
2004: Lambrechts Diether; Carmeliet Peter
Genetics in zebrafish, mice, and humans to dissect congenital heart disease: insights in the role of VEGF.
Current topics in developmental biology 2004;62():189-224.
2004: Conway Edward M; Carmeliet Peter
The diversity of endothelial cells: a challenge for therapeutic angiogenesis.
Genome biology 2004;5(2):207.
2003: Compernolle Veerle; Brusselmans Koen; Franco Diego; Moorman Antoon; Dewerchin Mieke; Collen Désiré; Carmeliet Peter
Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha.
Cardiovascular research 2003;60(3):569-79.
2003: Drixler T A; Vogten J M; Gebbink M F B G; Carmeliet P; Voest E E; Borel Rinkes I H M
Plasminogen mediates liver regeneration and angiogenesis after experimental partial hepatectomy.
The British journal of surgery 2003;90(11):1384-90.
2003: Dewerchin Mieke; Hérault Jean-Pascal; Wallays Goedele; Petitou Maurice; Schaeffer Paul; Millet Laurence; Weitz Jeffrey I; Moons Lieve; Collen Désiré; Carmeliet Peter; Herbert Jean-Marc
Life-threatening thrombosis in mice with targeted Arg48-to-Cys mutation of the heparin-binding domain of antithrombin.
Circulation research 2003;93(11):1120-6.
2003: Janssen Anneleen; Gressens Pierre; Grabenbauer Markus; Baumgart Eveline; Schad Arno; Vanhorebeek Ilse; Brouwers Annelies; Declercq Peter E; Fahimi Dariush; Evrard Philippe; Schoonjans Luc; Collen Désiré; Carmeliet Peter; Mannaerts Guy; Van Veldhoven Paul; Baes Myriam
Neuronal migration depends on intact peroxisomal function in brain and in extraneuronal tissues.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(30):9732-41.
2003: Van Cromphaut S J; Rummens K; Stockmans I; Van Herck E; Dijcks F A; Ederveen A G H; Carmeliet P; Verhaeghe J; Bouillon R; Carmeliet G
Intestinal calcium transporter genes are upregulated by estrogens and the reproductive cycle through vitamin D receptor-independent mechanisms.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(10):1725-36.
2003: Tjwa Marc; Luttun Aernout; Autiero Monica; Carmeliet Peter
VEGF and PlGF: two pleiotropic growth factors with distinct roles in development and homeostasis.
Cell and tissue research 2003;314(1):5-14.
2003: Hertig Alexandre; Berrou Jeannig; Allory Yves; Breton Laetitia; Commo Frédéric; Costa De Beauregard Marie-Alyette; Carmeliet Peter; Rondeau Eric
Type 1 plasminogen activator inhibitor deficiency aggravates the course of experimental glomerulonephritis through overactivation of transforming growth factor beta.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(13):1904-6.
2003: Molinas Carlos Roger; Campo Rudi; Dewerchin Mieke; Eriksson Ulf; Carmeliet Peter; Koninckx Philippe Robert
Role of vascular endothelial growth factor and placental growth factor in basal adhesion formation and in carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in transgenic mice.
Fertility and sterility 2003;80 Suppl 2():803-11.
2003: Molinas Carlos Roger; Campo Rudi; Elkelani Osama Ali; Binda Maria Mercedes; Carmeliet Peter; Koninckx Philippe Robert
Role of hypoxia inducible factors 1alpha and 2alpha in basal adhesion formation and in carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in transgenic mice.
Fertility and sterility 2003;80 Suppl 2():795-802.
2003: Conway Edward M; Carmeliet Peter
Cardiovascular biology: signalling silenced.
Nature 2003;425(6954):139-41.
2003: Carmeliet Peter
Blood vessels and nerves: common signals, pathways and diseases.
Nature reviews. Genetics 2003;4(9):710-20.
2003: Brites Pedro; Motley Alison M; Gressens Pierre; Mooyer Petra A W; Ploegaert Ingrid; Everts Vincent; Evrard Philippe; Carmeliet Peter; Dewerchin Mieke; Schoonjans Luc; Duran Marinus; Waterham Hans R; Wanders Ronald J A; Baes Myriam
Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata.
Human molecular genetics 2003;12(18):2255-67.
2003: Rijneveld Anita W; Florquin Sandrine; Bresser Paul; Levi Marcel; De Waard Vivian; Lijnen Roger; Van Der Zee Jaring S; Speelman Peter; Carmeliet Peter; Van Der Poll Tom
Plasminogen activator inhibitor type-1 deficiency does not influence the outcome of murine pneumococcal pneumonia.
Blood 2003;102(3):934-9.
2003: Autiero M; Luttun A; Tjwa M; Carmeliet P
Placental growth factor and its receptor, vascular endothelial growth factor receptor-1: novel targets for stimulation of ischemic tissue revascularization and inhibition of angiogenic and inflammatory disorders.
Journal of thrombosis and haemostasis : JTH 2003;1(7):1356-70.
2003: Molinas Carlos Roger; Elkelani Osama; Campo Rudi; Luttun Aernout; Carmeliet Peter; Koninckx Philippe Robert
Role of the plasminogen system in basal adhesion formation and carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in transgenic mice.
Fertility and sterility 2003;80(1):184-92.
2003: Rakic Jean-Marie; Lambert Vincent; Devy Laetitia; Luttun Aernout; Carmeliet Peter; Claes Carel; Nguyen Laurent; Foidart Jean-Michel; Noël Agnès; Munaut Carine
Placental growth factor, a member of the VEGF family, contributes to the development of choroidal neovascularization.
Investigative ophthalmology & visual science 2003;44(7):3186-93.
2003: Autiero Monica; Waltenberger Johannes; Communi Didier; Kranz Andrea; Moons Lieve; Lambrechts Diether; Kroll Jens; Plaisance Stephane; De Mol Maria; Bono Françoise; Kliche Stefanie; Fellbrich Guido; Ballmer-Hofer Kurt; Maglione Domenico; Mayr-Beyrle Ulrike; Dewerchin Mieke; Dombrowski Saskia; Stanimirovic Danica; Van Hummelen Paul; Dehio Christoph; Hicklin Daniel J; Persico Graziella; Herbert Jean-Marc; Communi David; Shibuya Masabumi; Collen Désiré; Conway Edward M; Carmeliet Peter
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1.
Nature medicine 2003;9(7):936-43.
2003: Reijerkerk Arie; Mosnier Laurent O; Kranenburg Onno; Bouma Bonno N; Carmeliet Peter; Drixler Tom; Meijers Joost C M; Voest Emile E; Gebbink Martijn F B G
Amyloid endostatin induces endothelial cell detachment by stimulation of the plasminogen activation system.
Molecular cancer research : MCR 2003;1(8):561-8.
2003: Carmeliet Peter
Angiogenesis in health and disease.
Nature medicine 2003;9(6):653-60.
2003: Lambert Vincent; Munaut Carine; Carmeliet Peter; Gerard Robert D; Declerck Paul J; Gils Ann; Claes Carel; Foidart Jean-Michel; Noël Agnès; Rakic Jean-Marie
Dose-dependent modulation of choroidal neovascularization by plasminogen activator inhibitor type I: implications for clinical trials.
Investigative ophthalmology & visual science 2003;44(6):2791-7.
2003: Kitching A Richard; Kong Yao Z; Huang Xiao Ru; Davenport Piers; Edgtton Kristy L; Carmeliet Peter; Holdsworth Stephen R; Tipping Peter G
Plasminogen activator inhibitor-1 is a significant determinant of renal injury in experimental crescentic glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2003;14(6):1487-95.
2003: Deindl E; Ziegelhöffer T; Kanse S M; Fernandez B; Neubauer E; Carmeliet P; Preissner K T; Schaper W
Receptor-independent role of the urokinase-type plasminogen activator during arteriogenesis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1174-6.
2003: Levi Marcel; Dörffler-Melly Janine; Reitsma Pieter; Buller Harry; Florquin Sandrine; van der Poll Tom; Carmeliet Peter
Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice.
Blood 2003;101(12):4823-7.
2003: Luttun Aernout; Carmeliet Peter
De novo vasculogenesis in the heart.
Cardiovascular research 2003;58(2):378-89.
2003: Brusselmans Koen; Compernolle Veerle; Tjwa Marc; Wiesener Michael S; Maxwell Patrick H; Collen Désiré; Carmeliet Peter
Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia.
The Journal of clinical investigation 2003;111(10):1519-27.
2003: Zhang Guoqiang; Kim Heungsoo; Cai Xiaohe; López-Guisa Jesús M; Alpers Charles E; Liu Youhua; Carmeliet Peter; Eddy Allison A
Urokinase receptor deficiency accelerates renal fibrosis in obstructive nephropathy.
Journal of the American Society of Nephrology : JASN 2003;14(5):1254-71.
2003: Zhang Guoqiang; Kim Heungsoo; Cai Xiaohe; Lopez-Guisa Jesus M; Carmeliet Peter; Eddy Allison A
Urokinase receptor modulates cellular and angiogenic responses in obstructive nephropathy.
Journal of the American Society of Nephrology : JASN 2003;14(5):1234-53.
2003: Roca Cristina; Primo Luca; Valdembri Donatella; Cividalli Anna; Declerck Paul; Carmeliet Peter; Gabriele Pietro; Bussolino Federico
Hyperthermia inhibits angiogenesis by a plasminogen activator inhibitor 1-dependent mechanism.
Cancer research 2003;63(7):1500-7.
2003: Rakic Jean-Marie; Lambert Vincent; Munaut Carine; Bajou Khalid; Peyrollier Karine; Alvarez-Gonzalez Marie-Luz; Carmeliet Peter; Foidart Jean-Michel; Noël Agnès
Mice without uPA, tPA, or plasminogen genes are resistant to experimental choroidal neovascularization.
Investigative ophthalmology & visual science 2003;44(4):1732-9.
2003: Gruss Claus J; Satyamoorthy Kapaettu; Berking Carola; Lininger John; Nesbit Mark; Schaider Helmut; Liu Zhao-June; Oka Masahiro; Hsu Mei-Yu; Shirakawa Takashi; Li Gang; Bogenrieder Thomas; Carmeliet Peter; El-Deiry Wafik S; Eck Stephen L; Rao Justi S; Baker Andrew H; Bennet Jean T; Crombleholme Timothy M; Velazquez Omaida; Karmacharya Jagajan; Margolis David J; Wilson James M; Detmar Michael; Skobe Mihaela; Robbins Paul D; Buck Clayton; Herlyn Meenhard
Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice.
The Journal of investigative dermatology 2003;120(4):683-92.
2003: Fabritz Larissa; Kirchhof Paulus; Franz Michael R; Nuyens Dieter; Rossenbacker Tom; Ottenhof Alexander; Haverkamp Wilhelm; Breithardt Günter; Carmeliet Edward; Carmeliet Peter
Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in DeltaKPQ SCN5A (long QT3) mice.
Cardiovascular research 2003;57(4):1085-93.
2003: Luttun Aernout; Carmeliet Peter
Soluble VEGF receptor Flt1: the elusive preeclampsia factor discovered?
The Journal of clinical investigation 2003;111(5):600-2.
2003: Pipp Frederic; Heil Matthias; Issbrücker Katja; Ziegelhoeffer Tibor; Martin Sandra; van den Heuvel Joop; Weich Herbert; Fernandez Borja; Golomb Gershon; Carmeliet Peter; Schaper Wolfgang; Clauss Matthias
VEGFR-1-selective VEGF homologue PlGF is arteriogenic: evidence for a monocyte-mediated mechanism.
Circulation research 2003;92(4):378-85.
2003: Deng Gary G; Martin-McNulty Baby; Sukovich Drew A; Freay Ana; Halks-Miller Meredith; Thinnes Therese; Loskutoff David J; Carmeliet Peter; Dole William P; Wang Yi-Xin
Urokinase-type plasminogen activator plays a critical role in angiotensin II-induced abdominal aortic aneurysm.
Circulation research 2003;92(5):510-7.
2003: Scholz Dimitri; Elsaesser Hanno; Sauer Annegret; Friedrich Christian; Luttun Aernout; Carmeliet Peter; Schaper Wolfgang
Bone marrow transplantation abolishes inhibition of arteriogenesis in placenta growth factor (PlGF) -/- mice.
Journal of molecular and cellular cardiology 2003;35(2):177-84.
2003: Oura Hajimu; Bertoncini Jennifer; Velasco Paula; Brown Lawrence F; Carmeliet Peter; Detmar Michael
A critical role of placental growth factor in the induction of inflammation and edema formation.
Blood 2003;101(2):560-7.
2003: Jin Tao; Tarkowski Andrej; Carmeliet Peter; Bokarewa Maria
Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis.
Arthritis research & therapy 2003;5(1):R9-R17.
2002: Luttun Aernout; Tjwa Marc; Carmeliet Peter
Placental growth factor (PlGF) and its receptor Flt-1 (VEGFR-1): novel therapeutic targets for angiogenic disorders.
Annals of the New York Academy of Sciences 2002;979():80-93.
2002: Docagne Fabian; Nicole Olivier; Gabriel Cecilia; Fernández-Monreal Mónica; Lesné Sylvain; Ali Carine; Plawinski Laurent; Carmeliet Peter; MacKenzie Eric T; Buisson Alain; Vivien Denis
Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-beta 1 against NMDA-induced necrosis.
Molecular and cellular neurosciences 2002;21(4):634-44.
2002: de Waard Vivian; Arkenbout E Karin; Carmeliet Peter; Lindner Volkhard; Pannekoek Hans
Plasminogen activator inhibitor 1 and vitronectin protect against stenosis in a murine carotid artery ligation model.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(12):1978-83.
2002: Blasi Francesco; Carmeliet Peter
uPAR: a versatile signalling orchestrator.
Nature reviews. Molecular cell biology 2002;3(12):932-43.
2002: Pawlinski R; Fernandes A; Kehrle B; Pedersen B; Parry G; Erlich J; Pyo R; Gutstein D; Zhang J; Castellino F; Melis E; Carmeliet P; Baretton G; Luther T; Taubman M; Rosen E; Mackman N
Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15333-8.
2002: Luttun Aernout; Tjwa Marc; Moons Lieve; Wu Yan; Angelillo-Scherrer Anne; Liao Fang; Nagy Janice A; Hooper Andrea; Priller Josef; De Klerck Bert; Compernolle Veerle; Daci Evis; Bohlen Peter; Dewerchin Mieke; Herbert Jean-Marc; Fava Roy; Matthys Patrick; Carmeliet Geert; Collen Désiré; Dvorak Harold F; Hicklin Daniel J; Carmeliet Peter
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.
Nature medicine 2002;8(8):831-40.
2002: Luttun Aernout; Brusselmans Koen; Fukao Hideharu; Tjwa Marc; Ueshima Shigeru; Herbert Jean-Marc; Matsuo Osamu; Collen Désiré; Carmeliet Peter; Moons Lieve
Loss of placental growth factor protects mice against vascular permeability in pathological conditions.
Biochemical and biophysical research communications 2002;295(2):428-34.
2002: Compernolle Veerle; Brusselmans Koen; Acker Till; Hoet Peter; Tjwa Marc; Beck Heike; Plaisance Stéphane; Dor Yuval; Keshet Eli; Lupu Florea; Nemery Benoit; Dewerchin Mieke; Van Veldhoven Paul; Plate Karl; Moons Lieve; Collen Désiré; Carmeliet Peter
Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice.
Nature medicine 2002;8(7):702-10.
2002: Mattot Virginie; Moons Lieve; Lupu Florea; Chernavvsky Daniel; Gómez R Ariel; Collen Désiré; Carmeliet Peter
Loss of the VEGF(164) and VEGF(188) isoforms impairs postnatal glomerular angiogenesis and renal arteriogenesis in mice.
Journal of the American Society of Nephrology : JASN 2002;13(6):1548-60.
2002: Alitalo Kari; Carmeliet Peter
Molecular mechanisms of lymphangiogenesis in health and disease.
Cancer cell 2002;1(3):219-27.
2002: Dor Yuval; Djonov Valentin; Abramovitch Rinat; Itin Ahuva; Fishman Glenn I; Carmeliet Peter; Goelman Gadi; Keshet Eli
Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy.
The EMBO journal 2002;21(8):1939-47.
2002: Beck Heike; Acker Till; Püschel Andreas W; Fujisawa Hajime; Carmeliet Peter; Plate Karl H
Cell type-specific expression of neuropilins in an MCA-occlusion model in mice suggests a potential role in post-ischemic brain remodeling.
Journal of neuropathology and experimental neurology 2002;61(4):339-50.
2002: Suelves Mònica; López-Alemany Roser; Lluís Frederic; Aniorte Gloria; Serrano Erika; Parra Maribel; Carmeliet Peter; Muñoz-Cánoves Pura
Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo.
Blood 2002;99(8):2835-44.
2002: Rijneveld Anita W; Levi Marcel; Florquin Sandrine; Speelman Peter; Carmeliet Peter; van Der Poll Tom
Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3507-11.
2002: Luttun Aernout; Lupu Florea; Storkebaum Erik; Hoylaerts Marc F; Moons Lieve; Crawley James; Bono Françoise; Poole A Robin; Tipping Peter; Herbert Jean-Marc; Collen Désiré; Carmeliet Peter
Lack of plasminogen activator inhibitor-1 promotes growth and abnormal matrix remodeling of advanced atherosclerotic plaques in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(3):499-505.
2002: Carmeliet Peter; Storkebaum Erik
Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders.
Seminars in cell & developmental biology 2002;13(1):39-53.
2002: Baes M; Dewerchin M; Janssen A; Collen D; Carmeliet P
Generation of Pex5-loxP mice allowing the conditional elimination of peroxisomes.
Genesis (New York, N.Y. : 2000) 2002;32(2):177-8.
2002: Kojima Hidefumi; Gu Hua; Nomura Saeko; Caldwell Charles C; Kobata Tetsuji; Carmeliet Peter; Semenza Gregg L; Sitkovsky Michail V
Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1alpha -deficient chimeric mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2170-4.
2002: Luttun Aernout; Carmeliet Geert; Carmeliet Peter
Vascular progenitors: from biology to treatment.
Trends in cardiovascular medicine 2002;12(2):88-96.
2002: Stalmans Ingeborg; Ng Yin-Shan; Rohan Richard; Fruttiger Marcus; Bouché Ann; Yuce Ali; Fujisawa Hajime; Hermans Bart; Shani Moshe; Jansen Sandra; Hicklin Dan; Anderson David J; Gardiner Tom; Hammes Hans-Peter; Moons Lieve; Dewerchin Mieke; Collen Désiré; Carmeliet Peter; D'Amore Patricia A
Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms.
The Journal of clinical investigation 2002;109(3):327-36.
2002: Devy Laetitia; Blacher Silvia; Grignet-Debrus Christine; Bajou Khalid; Masson Veronique; Gerard Robert D; Gils Ann; Carmeliet Geert; Carmeliet Peter; Declerck Paul J; Nöel Agnès; Foidart Jean-Michel
The pro- or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(2):147-54.
2002: Maes Christa; Carmeliet Peter; Moermans Karen; Stockmans Ingrid; Smets Nico; Collen Désiré; Bouillon Roger; Carmeliet Geert
Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.
Mechanisms of development 2002;111(1-2):61-73.
2002: Carmeliet Peter
Integrin indecision.
Nature medicine 2002;8(1):14-6.
2001: Luttun A; Carmeliet P
Genetic studies on the role of proteinases and growth factors in atherosclerosis and aneurysm formation.
Annals of the New York Academy of Sciences 2001;947():124-32; discussion 132-3.
2001: Van Cromphaut S J; Dewerchin M; Hoenderop J G; Stockmans I; Van Herck E; Kato S; Bindels R J; Collen D; Carmeliet P; Bouillon R; Carmeliet G
Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13324-9.
2001: Ver Heyen M; Heymans S; Antoons G; Reed T; Periasamy M; Awede B; Lebacq J; Vangheluwe P; Dewerchin M; Collen D; Sipido K; Carmeliet P; Wuytack F
Replacement of the muscle-specific sarcoplasmic reticulum Ca(2+)-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart.
Circulation research 2001;89(9):838-46.
2001: Brusselmans K; Bono F; Maxwell P; Dor Y; Dewerchin M; Collen D; Herbert J M; Carmeliet P
Hypoxia-inducible factor-2alpha (HIF-2alpha) is involved in the apoptotic response to hypoglycemia but not to hypoxia.
The Journal of biological chemistry 2001;276(42):39192-6.
2001: Nuyens D; Stengl M; Dugarmaa S; Rossenbacker T; Compernolle V; Rudy Y; Smits J F; Flameng W; Clancy C E; Moons L; Vos M A; Dewerchin M; Benndorf K; Collen D; Carmeliet E; Carmeliet P
Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.
Nature medicine 2001;7(9):1021-7.
2001: Holst-Hansen C; Low J A; Stephens R W; Johnson M D; Carmeliet P; Frandsen T L; Brünner N; Dickson R B
Increased stromal expression of murine urokinase plasminogen activator in a human breast cancer xenograft model following treatment with the matrix metalloprotease inhibitor, batimastat.
Breast cancer research and treatment 2001;68(3):225-37.
2001: Carmeliet P
Biomedicine. Clotting factors build blood vessels.
Science (New York, N.Y.) 2001;293(5535):1602-4.
2001: Melis E; Moons L; De Mol M; Herbert J M; Mackman N; Collen D; Carmeliet P; Dewerchin M
Targeted deletion of the cytosolic domain of tissue factor in mice does not affect development.
Biochemical and biophysical research communications 2001;286(3):580-6.
2001: Carmeliet P; Luttun A
The emerging role of the bone marrow-derived stem cells in (therapeutic) angiogenesis.
Thrombosis and haemostasis 2001;86(1):289-97.
2001: Brown E B; Campbell R B; Tsuzuki Y; Xu L; Carmeliet P; Fukumura D; Jain R K
In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy.
Nature medicine 2001;7(7):864-8.
2001: Rajantie I; Ekman N; Iljin K; Arighi E; Gunji Y; Kaukonen J; Palotie A; Dewerchin M; Carmeliet P; Alitalo K
Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium.
Molecular and cellular biology 2001;21(14):4647-55.
2001: Carmeliet P; Moons L; Luttun A; Vincenti V; Compernolle V; De Mol M; Wu Y; Bono F; Devy L; Beck H; Scholz D; Acker T; DiPalma T; Dewerchin M; Noel A; Stalmans I; Barra A; Blacher S; Vandendriessche T; Ponten A; Eriksson U; Plate K H; Foidart J M; Schaper W; Charnock-Jones D S; Hicklin D J; Herbert J M; Collen D; Persico M G
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.
Nature medicine 2001;7(5):575-83.
2001: Dor Y; Camenisch T D; Itin A; Fishman G I; McDonald J A; Carmeliet P; Keshet E
A novel role for VEGF in endocardial cushion formation and its potential contribution to congenital heart defects.
Development (Cambridge, England) 2001;128(9):1531-8.
2001: Levi M; Moons L; Bouché A; Shapiro S D; Collen D; Carmeliet P
Deficiency of urokinase-type plasminogen activator-mediated plasmin generation impairs vascular remodeling during hypoxia-induced pulmonary hypertension in mice.
Circulation 2001;103(15):2014-20.
2001: Lambert V; Munaut C; Noël A; Frankenne F; Bajou K; Gerard R; Carmeliet P; Defresne M P; Foidart J M; Rakic J M
Influence of plasminogen activator inhibitor type 1 on choroidal neovascularization.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):1021-7.
2001: Kadambi A; Mouta Carreira C; Yun C O; Padera T P; Dolmans D E; Carmeliet P; Fukumura D; Jain R K
Vascular endothelial growth factor (VEGF)-C differentially affects tumor vascular function and leukocyte recruitment: role of VEGF-receptor 2 and host VEGF-A.
Cancer research 2001;61(6):2404-8.
2001: Lluís F; Roma J; Suelves M; Parra M; Aniorte G; Gallardo E; Illa I; Rodríguez L; Hughes S M; Carmeliet P; Roig M; Muñoz-Cánoves P
Urokinase-dependent plasminogen activation is required for efficient skeletal muscle regeneration in vivo.
Blood 2001;97(6):1703-11.
2001: Bajou K; Masson V; Gerard R D; Schmitt P M; Albert V; Praus M; Lund L R; Frandsen T L; Brunner N; Dano K; Fusenig N E; Weidle U; Carmeliet G; Loskutoff D; Collen D; Carmeliet P; Foidart J M; Noël A
The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies.
The Journal of cell biology 2001;152(4):777-84.
2001: Angelillo-Scherrer A; de Frutos P; Aparicio C; Melis E; Savi P; Lupu F; Arnout J; Dewerchin M; Hoylaerts M; Herbert J; Collen D; Dahlbäck B; Carmeliet P
Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.
Nature medicine 2001;7(2):215-21.
2001: Conway E M; Collen D; Carmeliet P
Molecular mechanisms of blood vessel growth.
Cardiovascular research 2001;49(3):507-21.
2001: Frandsen T L; Holst-Hansen C; Nielsen B S; Christensen I J; Nyengaard J R; Carmeliet P; Brünner N
Direct evidence of the importance of stromal urokinase plasminogen activator (uPA) in the growth of an experimental human breast cancer using a combined uPA gene-disrupted and immunodeficient xenograft model.
Cancer research 2001;61(2):532-7.
2001: Nicole O; Docagne F; Ali C; Margaill I; Carmeliet P; MacKenzie E T; Vivien D; Buisson A
The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.
Nature medicine 2001;7(1):59-64.
2000: Tsuzuki Y; Fukumura D; Oosthuyse B; Koike C; Carmeliet P; Jain R K
Vascular endothelial growth factor (VEGF) modulation by targeting hypoxia-inducible factor-1alpha--> hypoxia response element--> VEGF cascade differentially regulates vascular response and growth rate in tumors.
Cancer research 2000;60(22):6248-52.
2000: Carmeliet P; Jain R K
Angiogenesis in cancer and other diseases.
Nature 2000;407(6801):249-57.
2000: Creemers E; Cleutjens J; Smits J; Heymans S; Moons L; Collen D; Daemen M; Carmeliet P
Disruption of the plasminogen gene in mice abolishes wound healing after myocardial infarction.
The American journal of pathology 2000;156(6):1865-73.
2000: Carmeliet P
Proteinases in cardiovascular aneurysms and rupture: targets for therapy?
The Journal of clinical investigation 2000;105(11):1519-20.
2000: Carmeliet P; Collen D
Molecular basis of angiogenesis. Role of VEGF and VE-cadherin.
Annals of the New York Academy of Sciences 2000;902():249-62; discussion 262-4.
2000: Baes M; Huyghe S; Carmeliet P; Declercq P E; Collen D; Mannaerts G P; Van Veldhoven P P
Inactivation of the peroxisomal multifunctional protein-2 in mice impedes the degradation of not only 2-methyl-branched fatty acids and bile acid intermediates but also of very long chain fatty acids.
The Journal of biological chemistry 2000;275(21):16329-36.
2000: Carmeliet P
Mechanisms of angiogenesis and arteriogenesis.
Nature medicine 2000;6(4):389-95.
2000: Dewerchin M; Liang Z; Moons L; Carmeliet P; Castellino F J; Collen D; Rosen E D
Blood coagulation factor X deficiency causes partial embryonic lethality and fatal neonatal bleeding in mice.
Thrombosis and haemostasis 2000;83(2):185-90.
2000: Carmeliet P; Collen D
Transgenic mouse models in angiogenesis and cardiovascular disease.
The Journal of pathology 2000;190(3):387-405.
2000: Carmeliet P
Gene targeting and gene transfer to unravel the molecular basis of the formation and disorders of blood vessels.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2000;62(1):31-68.
1999: Ny A; Leonardsson G; Hägglund A C; Hägglöf P; Ploplis V A; Carmeliet P; Ny T
Ovulation in plasminogen-deficient mice.
Endocrinology 1999;140(11):5030-5.
1999: Heymans S; Luttun A; Nuyens D; Theilmeier G; Creemers E; Moons L; Dyspersin G D; Cleutjens J P; Shipley M; Angellilo A; Levi M; Nübe O; Baker A; Keshet E; Lupu F; Herbert J M; Smits J F; Shapiro S D; Baes M; Borgers M; Collen D; Daemen M J; Carmeliet P
Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure.
Nature medicine 1999;5(10):1135-42.
1999: Carmeliet P; Lampugnani M G; Moons L; Breviario F; Compernolle V; Bono F; Balconi G; Spagnuolo R; Oosthuyse B; Dewerchin M; Zanetti A; Angellilo A; Mattot V; Nuyens D; Lutgens E; Clotman F; de Ruiter M C; Gittenberger-de Groot A; Poelmann R; Lupu F; Herbert J M; Collen D; Dejana E
Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.
Cell 1999;98(2):147-57.
1999: Erlich J; Parry G C; Fearns C; Muller M; Carmeliet P; Luther T; Mackman N
Tissue factor is required for uterine hemostasis and maintenance of the placental labyrinth during gestation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):8138-43.
1999: Lijnen H R; Lupu F; Moons L; Carmeliet P; Goulding D; Collen D
Temporal and topographic matrix metalloproteinase expression after vascular injury in mice.
Thrombosis and haemostasis 1999;81(5):799-807.
1999: Nagai N; De Mol M; Lijnen H R; Carmeliet P; Collen D
Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice.
Circulation 1999;99(18):2440-4.
1999: Conway E M; Pollefeyt S; Cornelissen J; DeBaere I; Steiner-Mosonyi M; Weitz J I; Weiler-Guettler H; Carmeliet P; Collen D
Structure-function analyses of thrombomodulin by gene-targeting in mice: the cytoplasmic domain is not required for normal fetal development.
Blood 1999;93(10):3442-50.
1999: Carmeliet P; Ng Y S; Nuyens D; Theilmeier G; Brusselmans K; Cornelissen I; Ehler E; Kakkar V V; Stalmans I; Mattot V; Perriard J C; Dewerchin M; Flameng W; Nagy A; Lupu F; Moons L; Collen D; D'Amore P A; Shima D T
Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.
Nature medicine 1999;5(5):495-502.
1999: Chan J C; Carmeliet P; Moons L; Rosen E D; Huang Z F; Broze G J; Collen D; Castellino F J
Factor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit.
The Journal of clinical investigation 1999;103(4):475-82.
1999: Carmeliet P; Collen D
Role of vascular endothelial growth factor and vascular endothelial growth factor receptors in vascular development.
Current topics in microbiology and immunology 1999;237():133-58.
1998: Moons L; Shi C; Ploplis V; Plow E; Haber E; Collen D; Carmeliet P
Reduced transplant arteriosclerosis in plasminogen-deficient mice.
The Journal of clinical investigation 1998;102(10):1788-97.
1998: Jalbert L R; Rosen E D; Moons L; Chan J C; Carmeliet P; Collen D; Castellino F J
Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice.
The Journal of clinical investigation 1998;102(8):1481-8.
1998: Carmeliet P; Collen D
Development and disease in proteinase-deficient mice: role of the plasminogen, matrix metalloproteinase and coagulation system.
Thrombosis research 1998;91(6):255-85.
1998: Pinsky D J; Liao H; Lawson C A; Yan S F; Chen J; Carmeliet P; Loskutoff D J; Stern D M
Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition.
The Journal of clinical investigation 1998;102(5):919-28.
1998: Bajou K; Noël A; Gerard R D; Masson V; Brunner N; Holst-Hansen C; Skobe M; Fusenig N E; Carmeliet P; Collen D; Foidart J M
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.
Nature medicine 1998;4(8):923-8.
1998: Carmeliet P; Moons L; Collen D
Mouse models of angiogenesis, arterial stenosis, atherosclerosis and hemostasis.
Cardiovascular research 1998;39(1):8-33.
1998: Carmeliet P; Dor Y; Herbert J M; Fukumura D; Brusselmans K; Dewerchin M; Neeman M; Bono F; Abramovitch R; Maxwell P; Koch C J; Ratcliffe P; Moons L; Jain R K; Collen D; Keshert E;
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis.
Nature 1998;394(6692):485-90.
1998: Liang Z; Cooper A; DeFord M E; Carmeliet P; Collen D; Castellino F J; Rosen E D
Cloning and characterization of a cDNA encoding murine coagulation factor X.
Thrombosis and haemostasis 1998;80(1):87-91.
1998: Lijnen H R; Van Hoef B; Lupu F; Moons L; Carmeliet P; Collen D
Function of the plasminogen/plasmin and matrix metalloproteinase systems after vascular injury in mice with targeted inactivation of fibrinolytic system genes.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(7):1035-45.
1998: Carmeliet P; Collen D
Tissue factor.
The international journal of biochemistry & cell biology 1998;30(6):661-7.
1998: Carmeliet P; Collen D
Vascular development and disorders: molecular analysis and pathogenic insights.
Kidney international 1998;53(6):1519-49.
1998: Jalbert L R; Rosen E D; Lissens A; Carmeliet P; Collen D; Castellino F J
Nucleotide structure and characterization of the murine gene encoding anticoagulant protein C.
Thrombosis and haemostasis 1998;79(2):310-6.
1998: Parry G C; Erlich J H; Carmeliet P; Luther T; Mackman N
Low levels of tissue factor are compatible with development and hemostasis in mice.
The Journal of clinical investigation 1998;101(3):560-9.
1998: Carmeliet P; Moons L; Dewerchin M; Rosenberg S; Herbert J M; Lupu F; Collen D
Receptor-independent role of urokinase-type plasminogen activator in pericellular plasmin and matrix metalloproteinase proteolysis during vascular wound healing in mice.
The Journal of cell biology 1998;140(1):233-45.
1997: Carmeliet P; Moons L; Lijnen R; Baes M; Lemaître V; Tipping P; Drew A; Eeckhout Y; Shapiro S; Lupu F; Collen D
Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation.
Nature genetics 1997;17(4):439-44.
1997: Carmeliet P; Moons L; Lijnen R; Janssens S; Lupu F; Collen D; Gerard R D
Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice.
Circulation 1997;96(9):3180-91.
1997: Rosen E D; Chan J C; Idusogie E; Clotman F; Vlasuk G; Luther T; Jalbert L R; Albrecht S; Zhong L; Lissens A; Schoonjans L; Moons L; Collen D; Castellino F J; Carmeliet P
Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.
Nature 1997;390(6657):290-4.
1997: Carmeliet P; Collen D
Molecular analysis of blood vessel formation and disease.
The American journal of physiology 1997;273(5 Pt 2):H2091-104.
1997: Carmeliet P; Moons L; Herbert J M; Crawley J; Lupu F; Lijnen R; Collen D
Urokinase but not tissue plasminogen activator mediates arterial neointima formation in mice.
Circulation research 1997;81(5):829-39.
1997: Baes M; Gressens P; Baumgart E; Carmeliet P; Casteels M; Fransen M; Evrard P; Fahimi D; Declercq P E; Collen D; van Veldhoven P P; Mannaerts G P
A mouse model for Zellweger syndrome.
Nature genetics 1997;17(1):49-57.
1997: Carmeliet P; Stassen J M; Van Vlaenderen I; Meidell R S; Collen D; Gerard R D
Adenovirus-mediated transfer of tissue-type plasminogen activator augments thrombolysis in tissue-type plasminogen activator-deficient and plasminogen activator inhibitor-1-overexpressing mice.
Blood 1997;90(4):1527-34.
1997: Carmeliet P; Moons L; Dewerchin M; Mackman N; Luther T; Breier G; Ploplis V; Müller M; Nagy A; Plow E; Gerard R; Edgington T; Risau W; Collen D
Insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system.
Annals of the New York Academy of Sciences 1997;811():191-206.
1997: Ny A; Nordström L; Carmeliet P; Ny T
Studies of mice lacking plasminogen activator gene function suggest that plasmin production prior to ovulation exceeds the amount needed for optimal ovulation efficiency.
European journal of biochemistry / FEBS 1997;244(2):487-93.
1997: Carmeliet P; Moons L; Stassen J M; De Mol M; Bouché A; van den Oord J J; Kockx M; Collen D
Vascular wound healing and neointima formation induced by perivascular electric injury in mice.
The American journal of pathology 1997;150(2):761-76.
1997: Carmeliet P; Moons L; Ploplis V; Plow E; Collen D
Impaired arterial neointima formation in mice with disruption of the plasminogen gene.
The Journal of clinical investigation 1997;99(2):200-8.
1996: Idusogie E; Rosen E D; Carmeliet P; Collen D; Castellino F J
Nucleotide structure and characterization of the murine blood coagulation factor VII gene.
Thrombosis and haemostasis 1996;76(6):957-64.
1996: Carmeliet P; Collen D
Genetic analysis of the plasminogen and coagulation system in mice.
Haemostasis 1996;26 Suppl 4():132-53.
1996: Carmeliet P; Mackman N; Moons L; Luther T; Gressens P; Van Vlaenderen I; Demunck H; Kasper M; Breier G; Evrard P; Müller M; Risau W; Edgington T; Collen D
Role of tissue factor in embryonic blood vessel development.
Nature 1996;383(6595):73-5.
1996: Huang Y Y; Bach M E; Lipp H P; Zhuo M; Wolfer D P; Hawkins R D; Schoonjans L; Kandel E R; Godfraind J M; Mulligan R; Collen D; Carmeliet P
Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8699-704.
1996: Lijnen H R; Carmeliet P; Bouché A; Moons L; Ploplis V A; Plow E F; Collen D
Restoration of thrombolytic potential in plasminogen-deficient mice by bolus administration of plasminogen.
Blood 1996;88(3):870-6.
1996: Luther T; Flössel C; Mackman N; Bierhaus A; Kasper M; Albrecht S; Sage E H; Iruela-Arispe L; Grossmann H; Ströhlein A; Zhang Y; Nawroth P P; Carmeliet P; Loskutoff D J; Müller M
Tissue factor expression during human and mouse development.
The American journal of pathology 1996;149(1):101-13.
1996: Carmeliet P; Ferreira V; Breier G; Pollefeyt S; Kieckens L; Gertsenstein M; Fahrig M; Vandenhoeck A; Harpal K; Eberhardt C; Declercq C; Pawling J; Moons L; Collen D; Risau W; Nagy A
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele.
Nature 1996;380(6573):435-9.
1996: Idusogie E; Rosen E; Geng J P; Carmeliet P; Collen D; Castellino F J
Characterization of a cDNA encoding murine coagulation factor VII.
Thrombosis and haemostasis 1996;75(3):481-7.
1996: Dewerchin M; Nuffelen A V; Wallays G; Bouché A; Moons L; Carmeliet P; Mulligan R C; Collen D
Generation and characterization of urokinase receptor-deficient mice.
The Journal of clinical investigation 1996;97(3):870-8.
1996: Carmeliet P; Collen D
Gene manipulation and transfer of the plasminogen and coagulation system in mice.
Seminars in thrombosis and hemostasis 1996;22(6):525-42.
1995: Leonardsson G; Peng X R; Liu K; Nordström L; Carmeliet P; Mulligan R; Collen D; Ny T
Ovulation efficiency is reduced in mice that lack plasminogen activator gene function: functional redundancy among physiological plasminogen activators.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12446-50.
1995: Ploplis V A; Carmeliet P; Vazirzadeh S; Van Vlaenderen I; Moons L; Plow E F; Collen D
Effects of disruption of the plasminogen gene on thrombosis, growth, and health in mice.
Circulation 1995;92(9):2585-93.
1995: Carmeliet P; Collen D
Gene targeting and gene transfer studies of the biological role of the plasminogen/plasmin system.
Thrombosis and haemostasis 1995;74(1):429-36.
1995: Carmeliet P; Bouché A; De Clercq C; Janssen S; Pollefeyt S; Wyns S; Mulligan R C; Collen D
Biological effects of disruption of the tissue-type plasminogen activator, urokinase-type plasminogen activator, and plasminogen activator inhibitor-1 genes in mice.
Annals of the New York Academy of Sciences 1995;748():367-81; discussion 381-2.
1994: Carmeliet P; Mulligan R C; Collen D
Transgenic animals as tools for the study of fibrinolysis in vivo.
Journal of internal medicine 1994;236(4):455-9.
1994: Carmeliet P; Schoonjans L; Kieckens L; Ream B; Degen J; Bronson R; De Vos R; van den Oord J J; Collen D; Mulligan R C
Physiological consequences of loss of plasminogen activator gene function in mice.
Nature 1994;368(6470):419-24.
1993: Carmeliet P; Stassen J M; Schoonjans L; Ream B; van den Oord J J; De Mol M; Mulligan R C; Collen D
Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis.
The Journal of clinical investigation 1993;92(6):2756-60.
1993: Carmeliet P; Kieckens L; Schoonjans L; Ream B; van Nuffelen A; Prendergast G; Cole M; Bronson R; Collen D; Mulligan R C
Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization.
The Journal of clinical investigation 1993;92(6):2746-55.
1991: Carmeliet P; Vankelecom H; Van Damme J; Billiau A; Denef C
Release of interleukin-6 from anterior pituitary cell aggregates: developmental pattern and modulation by glucocorticoids and forskolin.
Neuroendocrinology 1991;53(1):29-34.
1990: Bauer K; Carmeliet P; Schulz M; Baes M; Denef C
Regulation and cellular localization of the membrane-bound thyrotropin-releasing hormone-degrading enzyme in primary cultures of neuronal, glial and adenohypophyseal cells.
Endocrinology 1990;127(3):1224-33.
1990: Allaerts W; Carmeliet P; Denef C
New perspectives in the function of pituitary folliculo-stellate cells.
Molecular and cellular endocrinology 1990;71(2):73-81.
1990: Vankelecom H; Carmeliet P; Heremans H; Van Damme J; Dijkmans R; Billiau A; Denef C
Interferon-gamma inhibits stimulated adrenocorticotropin, prolactin, and growth hormone secretion in normal rat anterior pituitary cell cultures.
Endocrinology 1990;126(6):2919-26.
1989: Carmeliet P; Maertens P; Denef C
Stimulation and inhibition of prolactin release from rat pituitary lactotrophs by the cholinomimetic carbachol in vitro. Influence of hormonal environment and intercellular contacts.
Molecular and cellular endocrinology 1989;63(1-2):121-31.
1989: Carmeliet P; Baes M; Denef C
The glucocorticoid hormone dexamethasone reverses the growth hormone-releasing properties of the cholinomimetic carbachol.
Endocrinology 1989;124(5):2625-34.
1989: Carmeliet P; Denef C
Synthesis and release of acetylcholine by normal and tumoral pituitary corticotrophs.
Endocrinology 1989;124(5):2218-27.
1989: Vankelecom H; Carmeliet P; Van Damme J; Billiau A; Denef C
Production of interleukin-6 by folliculo-stellate cells of the anterior pituitary gland in a histiotypic cell aggregate culture system.
Neuroendocrinology 1989;49(1):102-6.
1989: Denef C; Maertens P; Allaerts W; Mignon A; Robberecht W; Swennen L; Carmeliet P
Cell-to-cell communication in peptide target cells of anterior pituitary.
Methods in enzymology 1989;168():47-71.
1988: Carmeliet P; Denef C
Immunocytochemical and pharmacological evidence for an intrinsic cholinomimetic system modulating prolactin and growth hormone release in rat pituitary.
Endocrinology 1988;123(2):1128-39.

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