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Henry Earp

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Yuangang Liu; Mehmet Karaca; Z Zhang; D Gioeli; Henry Earp; Young E Whang
Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases.
Zuoan Yi; Li Li; Glenn K Matsushima; Henry Earp; Bo Wang; Roland Tisch
A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells.
Rebecca Cook; Melissa Sandahl; Karen Strunk; Leah C Miraglia; Carty Husted; Debra M Hunter; Klaus Elenius; Lewis A Chodosh; Henry Earp
ErbB4 splice variants Cyt1 and Cyt2 differ by 16 amino acids and exert opposing effects on the mammary epithelium in vivo.

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2010: Yuangang Liu; Mehmet Karaca; Z Zhang; D Gioeli; Henry Earp; Young E Whang
Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases.
Oncogene 2010;29(22):3208-16.
2009: Zuoan Yi; Li Li; Glenn K Matsushima; Henry Earp; Bo Wang; Roland Tisch
A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells.
Blood 2009;114(15):3191-8.
2009: Rebecca Cook; Melissa Sandahl; Karen Strunk; Leah C Miraglia; Carty Husted; Debra M Hunter; Klaus Elenius; Lewis A Chodosh; Henry Earp
ErbB4 splice variants Cyt1 and Cyt2 differ by 16 amino acids and exert opposing effects on the mammary epithelium in vivo.
Molecular and cellular biology 2009;29(18):4935-48.
2009: Mark A Wallet; Rafael R Flores; Yaming Wang; Zuoan Yi; Charles J Kroger; Clayton E Mathews; Henry Earp; Glenn K Matsushima; Bo Wang; Roland Tisch
MerTK regulates thymic selection of autoreactive T cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(12):4810-5.
2009: Shu-Mang Feng; Rebecca Cook; Debra Hunter; Melissa Sandahl; Laura S Caskey; Keiji Miyazawa; Azeddine Atfi; Henry Earp
The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation.
Molecular and cellular biology 2009;29(3):892-906.
2009: Julie C Williams; Robin R Craven; Henry Earp; Thomas H Kawula; Glenn K Matsushima
TAM receptors are dispensable in the phagocytosis and killing of bacteria.
Cellular immunology 2009;259(2):128-34.
2008: Rebecca Cook; Melissa Sandahl; Debra Hunter; Leah Miraglia; Henry Earp
Prolactin and ErbB4/HER4 signaling interact via Janus kinase 2 to induce mammary epithelial cell gene expression differentiation.
Molecular endocrinology (Baltimore, Md.) 2008;22(10):2307-21.
2008: Michael S O'Malley; Robert Blouin; Etta D Pisano; Barbara K Rimer; William L Roper; Henry Earp
Research for North Carolina: The University Cancer Research Fund.
North Carolina medical journal 2008;69(4):299-302.
2008: Rebecca Cook; Shu-Mang Feng; Karen Strunk; Henry Earp
ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.
Journal of mammary gland biology and neoplasia 2008;13(2):235-46.
2008: Robert C Millikan; Beth Newman; Chiu-Kit Tse; Patricia G Moorman; Kathleen Dorsey; Lynn Dressler; Lisa V Smith; Miriam H Labbok; Joseph Geradts; Jeannette T Bensen; Susan Jackson; Sarah Nyante; Chad A Livasy; Lisa A Carey; Henry Earp; Charles M Perou
Epidemiology of basal-like breast cancer.
Breast cancer research and treatment 2008;109(1):123-39.
2008: Anne Angelillo-Scherrer; Laurent Burnier; Diether Lambrechts; Richard J Fish; Marc Tjwa; Stephane Plaisance; Rocco Sugamele; Maria DeMol; Eduardo Martinez-Soria; Patrick H Maxwell; Greg Lemke; Stephen P Goff; Glenn K Matsushima; Henry Earp; Marc Chanson; Désiré Collen; Shozo Izui; Marc Schapira; Edward M Conway; Peter Carmeliet
Role of Gas6 in erythropoiesis and anemia in mice.
The Journal of clinical investigation 2008;118(2):583-96.
2008: Mark A Wallet; Pradip Sen; Rafael R Flores; Yaming Wang; Zuoan Yi; Yingsu Huang; Clayton E Mathews; Henry Earp; Glenn K Matsushima; Bo Wang; Roland Tisch
MerTK is required for apoptotic cell-induced T cell tolerance.
The Journal of experimental medicine 2008;205(1):219-32.
2008: Rachel M A Linger; Amy Kathleen Keating; Henry Earp; Douglas K. Graham
TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.
Advances in cancer research 2008;100():35-83.
2007: Ta-Chun Yuan; Fen-Fen Lin; Suresh Veeramani; Siu-Ju Chen; Henry Earp; Ming-Fong Lin
ErbB-2 via PYK2 upregulates the adhesive ability of androgen receptor-positive human prostate cancer cells.
Oncogene 2007;26(54):7552-9.
2007: Brian J Dewar; Olivia S Gardner; Ching-Shih Chen; Henry Earp; James M Samet; Lee M Graves
Capacitative calcium entry contributes to the differential transactivation of the epidermal growth factor receptor in response to thiazolidinediones.
Molecular pharmacology 2007;72(5):1146-56.
2007: Shu-Mang Feng; Carolyn I Sartor; Debra Hunter; Hong Zhou; Xihui Yang; Laura S Caskey; Ruth Dy; Rebecca Cook; Henry Earp
The HER4 cytoplasmic domain, but not its C terminus, inhibits mammary cell proliferation.
Molecular endocrinology (Baltimore, Md.) 2007;21(8):1861-76.
2007: Karen Strunk; Carty Husted; Leah C Miraglia; Melissa Sandahl; William A Rearick; Debra M Hunter; Henry Earp; Rebecca Cook
HER4 D-box sequences regulate mitotic progression and degradation of the nuclear HER4 cleavage product s80HER4.
Cancer research 2007;67(14):6582-90.
2007: Nupam P Mahajan; Yuanbo Liu; Samarpan Majumder; Maria R Warren; Carol Parker; James L Mohler; Henry Earp; Young E Whang
Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(20):8438-43.
2007: Heather M Seitz; Todd D Camenisch; Greg Lemke; Henry Earp; Glenn K Matsushima
Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5635-42.
2007: Pradip Sen; Mark A Wallet; Zuoan Yi; Yingsu Huang; Michael Henderson; Clayton E Mathews; Henry Earp; Glenn K Matsushima; Albert S Baldwin; Roland Tisch
Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells.
Blood 2007;109(2):653-60.
2006: Rebecca Cook; Laura S Caskey; Melissa Sandahl; Debra M Hunter; Carty Husted; Karen Strunk; Carolyn I Sartor; William A Rearick; Wesley McCall; Magdalene K Sgagias; Kenneth H Cowan; Henry Earp
Heregulin-dependent delay in mitotic progression requires HER4 and BRCA1.
Molecular and cellular biology 2006;26(17):6412-24.
2006: Rebecca Cook; Melissa Sandahl; Carty Husted; Debra Hunter; Leah Miraglia; Shu-mang Feng; Klaus Elenius; Henry Earp
The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells.
Molecular biology of the cell 2006;17(9):4118-29.
2006: Lisa A Carey; Charles M Perou; Chad A Livasy; Lynn Dressler; David Cowan; Kathleen Dorsey; Gamze Karaca; Melissa A Troester; Chiu-Kit Tse; Sharon N Edmiston; Sandra L Deming; Joseph Geradts; Mary Cheang; Torsten O Nielsen; Patricia G Moorman; Henry Earp; Robert C Millikan
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study.
JAMA : the journal of the American Medical Association 2006;295(21):2492-502.
2006: Douglas K. Graham; Dana B Salzberg; Joanne Kurtzberg; Susan Sather; Glenn K Matsushima; Amy Kathleen Keating; Xiayuan Liang; Mark A Lovell; Sara A Williams; Tom Dawson; Michael J Schell; Adil A Anwar; H Ralph Snodgrass; Henry Earp
Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(9):2662-9.
2005: Nupam P Mahajan; Young E Whang; James L Mohler; Henry Earp
Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox.
Cancer research 2005;65(22):10514-23.
2005: Yuanbo Liu; Samarpan Majumder; Wesley McCall; Carolyn I Sartor; James L Mohler; Christopher W Gregory; Henry Earp; Young E Whang
Inhibition of HER-2/neu kinase impairs androgen receptor recruitment to the androgen responsive enhancer.
Cancer research 2005;65(8):3404-9.
2005: Christopher W Gregory; Young E Whang; Wesley McCall; Xiaoyin Fei; Yuanbo Liu; Liliana A Ponguta; Frank S French; Elizabeth M Wilson; Henry Earp
Heregulin-induced activation of HER2 and HER3 increases androgen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(5):1704-12.
2005: Anne Angelillo-Scherrer; Laurent Burnier; Nathalie Flores; Pierre Savi; Maria DeMol; Paul Schaeffer; Jean-Marc Herbert; Greg Lemke; Stephen P Goff; Glenn K Matsushima; Henry Earp; Christian Vesin; Marc F Hoylaerts; Stephane Plaisance; Désiré Collen; Edward M Conway; Bernhard Wehrle-Haller; Peter Carmeliet
Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.
The Journal of clinical investigation 2005;115(2):237-46.
2004: Yuling Li; Nupam P Mahajan; Jennifer Webster-Cyriaque; Prasanna M Bhende; Gregory K Hong; Henry Earp; Shannon C Kenney
The C-mer gene is induced by Epstein-Barr virus immediate-early protein BRLF1.
Journal of virology 2004;78(21):11778-85.
2004: Elizabeth Dees; Karen P McKinnon; Jennifer J Kuhns; Kathryn A Chwastiak; Scotty Sparks; Mary Myers; Edward J Collins; Jeffrey Frelinger; Hendrik W van Deventer; Frances A Collichio; Lisa A Carey; Mark E Brecher; Mark Graham II; Henry Earp; Jonathan S Serody
Dendritic cells can be rapidly expanded ex vivo and safely administered in patients with metastatic breast cancer.
Cancer immunology, immunotherapy : CII 2004;53(9):777-85.
2004: Hong Zhou; Yeon-Shil Kim; Aaron Peletier; Wes McCall; Henry Earp; Carolyn I Sartor
Effects of the EGFR/HER2 kinase inhibitor GW572016 on EGFR- and HER2-overexpressing breast cancer cell line proliferation, radiosensitization, and resistance.
International journal of radiation oncology, biology, physics 2004;58(2):344-52.
2003: Olivia S Gardner; Brian J Dewar; Henry Earp; James M Samet; Lee M Graves
Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation.
The Journal of biological chemistry 2003;278(47):46261-9.
2003: Nupam P Mahajan; Henry Earp
An SH2 domain-dependent, phosphotyrosine-independent interaction between Vav1 and the Mer receptor tyrosine kinase: a mechanism for localizing guanine nucleotide-exchange factor action.
The Journal of biological chemistry 2003;278(43):42596-603.
2003: Benjamin F Calvo; Aaron M Levine; Mavie Marcos; Qu F Collins; Mary V Iacocca; Laura S Caskey; Christopher W Gregory; Yuhua Lin; Young E Whang; Henry Earp; James L Mohler
Human epidermal receptor-2 expression in prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):1087-97.
2003: Jacque L Duncan; Matthew M LaVail; Douglas Yasumura; Michael T Matthes; Haidong Yang; Nikolaus Trautmann; Aimee V Chappelow; Wei Feng; Henry Earp; Glenn K Matsushima; Douglas Vollrath
An RCS-like retinal dystrophy phenotype in mer knockout mice.
Investigative ophthalmology & visual science 2003;44(2):826-38.
2003: Jacque L Duncan; Haidong Yang; Douglas Vollrath; Douglas Yasumura; Michael T Matthes; Nikolaus Trautmann; Aimee V Chappelow; Wei Feng; Henry Earp; Glenn K Matsushima; Matthew M LaVail
Inherited retinal dystrophy in Mer knockout mice.
Advances in experimental medicine and biology 2003;533():165-72.
2003: Henry Earp; Benjamin F Calvo; Carolyn I Sartor
The EGF receptor family--multiple roles in proliferation, differentiation, and neoplasia with an emphasis on HER4.
Transactions of the American Clinical and Climatological Association 2003;114():315-33; discussion 333-4.
2002: Julie Y Reuther-Madrid; David Kashatus; Shaoqiong Chen; Xiong Li; John Westwick; Roger J Davis; Henry Earp; Cun-Yu Wang; Albert S Baldwin Jr
The p65/RelA subunit of NF-kappaB suppresses the sustained, antiapoptotic activity of Jun kinase induced by tumor necrosis factor.
Molecular and cellular biology 2002;22(23):8175-83.
2002: Vita M Golubovskaya; Lucia Beviglia; Li-Hui Xu; Henry Earp; Rolf J Craven; William G Cance
Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells.
The Journal of biological chemistry 2002;277(41):38978-87.
2002: Katherine L Guttridge; J Christopher Luft; Tom Dawson; Eva Kozlowska; Nupam P Mahajan; Brian Varnum; Henry Earp
Mer receptor tyrosine kinase signaling: prevention of apoptosis and alteration of cytoskeletal architecture without stimulation or proliferation.
The Journal of biological chemistry 2002;277(27):24057-66.
2002: Lee M Graves; Jun Han; Henry Earp
Transactivation of the EGF receptor: is the PDGF receptor an unexpected accomplice?
Molecular interventions 2002;2(4):208-12.
2002: Jeffrey P MacKeigan; Debra J Taxman; Deborah Hunter; Henry Earp; Lee M Graves; Jenny P-Y Ting
Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2091-9.
2002: Philip L Cohen; Roberto Caricchio; Valsamma Abraham; Todd D Camenisch; John Jennette; Robert A S Roubey; Henry Earp; Glenn K Matsushima; Elizabeth A Reap
Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase.
The Journal of experimental medicine 2002;196(1):135-40.
2001: Carolyn I Sartor; Hong Zhou; E Kozlowska; K Guttridge; E Kawata; Laura S Caskey; J Harrelson; N Hynes; Stephen Ethier; Benjamin F Calvo; Henry Earp
Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells.
Molecular and cellular biology 2001;21(13):4265-75.
2001: R S Scott; Eileen J McMahon; S M Pop; Elizabeth A Reap; Roberto Caricchio; Philip L Cohen; Henry Earp; Glenn K Matsushima
Phagocytosis and clearance of apoptotic cells is mediated by MER.
Nature 2001;411(6834):207-11.
2001: Joanna M Watson; T W Harding; Vita M Golubovskaya; J S Morris; D Hunter; X Li; J Stephen Haskill; Henry Earp
Inhibition of the calcium-dependent tyrosine kinase (CADTK) blocks monocyte spreading and motility.
The Journal of biological chemistry 2001;276(5):3536-42.
2000: Lee M Graves; Hedeel I Guy; P Kozlowski; Min Huang; Eduardo R Lazarowski; Marshall pope; M A Collins; E N Dahlstrand; Henry Earp; David R Evans
Regulation of carbamoyl phosphate synthetase by MAP kinase.
Nature 2000;403(6767):328-32.
1999: Q Lu; M Gore; Q Zhang; Todd D Camenisch; Sharon Boast; F Casagranda; C Lai; Michael Skinner; R Klein; Glenn K Matsushima; Henry Earp; S P Goff; Greg Lemke
Tyro-3 family receptors are essential regulators of mammalian spermatogenesis.
Nature 1999;398(6729):723-8.
1999: X Li; R C Dy; William G Cance; Lee M Graves; Henry Earp
Interactions between two cytoskeleton-associated tyrosine kinases: calcium-dependent tyrosine kinase and focal adhesion tyrosine kinase.
The Journal of biological chemistry 1999;274(13):8917-24.
1999: Todd D Camenisch; Beverly H Koller; Henry Earp; Glenn K Matsushima
A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3498-503.
1998: X Li; Jung Weon Lee; Lee M Graves; Henry Earp
Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway.
The EMBO journal 1998;17(9):2574-83.
1998: X Li; D Hunter; J Morris; J Stephen Haskill; Henry Earp
A calcium-dependent tyrosine kinase splice variant in human monocytes. Activation by a two-stage process involving adherence and a subsequent intracellular signal.
The Journal of biological chemistry 1998;273(16):9361-4.
1998: A E Brinson; Timothy Harding; Pamela Diliberto; Y He; X Li; D Hunter; Brian Herman; Henry Earp; Lee M Graves
Regulation of a calcium-dependent tyrosine kinase in vascular smooth muscle cells by angiotensin II and platelet-derived growth factor. Dependence on calcium and the actin cytoskeleton.
The Journal of biological chemistry 1998;273(3):1711-8.
1997: Desheng Chen; Jeffrey S Elmendorf; Ann Louise Olson; X Li; Henry Earp; Jeffrey Pessin
Osmotic shock stimulates GLUT4 translocation in 3T3L1 adipocytes by a novel tyrosine kinase pathway.
The Journal of biological chemistry 1997;272(43):27401-10.
1997: X Li; H Yu; Lee M Graves; Henry Earp
Protein kinase C and protein kinase A inhibit calcium-dependent but not stress-dependent c-Jun N-terminal kinase activation in rat liver epithelial cells.
The Journal of biological chemistry 1997;272(23):14996-5002.
1997: X Li; Henry Earp
Paxillin is tyrosine-phosphorylated by and preferentially associates with the calcium-dependent tyrosine kinase in rat liver epithelial cells.
The Journal of biological chemistry 1997;272(22):14341-8.
1997: Lee M Graves; Y He; J Lambert; D Hunter; X Li; Henry Earp
An intracellular calcium signal activates p70 but not p90 ribosomal S6 kinase in liver epithelial cells.
The Journal of biological chemistry 1997;272(3):1920-8.
1996: H Yu; X Li; G S Marchetto; R Dy; D Hunter; Benjamin F Calvo; Tom Dawson; M Wilm; R J Anderegg; Lee M Graves; Henry Earp
Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation.
The Journal of biological chemistry 1996;271(47):29993-8.
1995: Henry Earp; W R Huckle; Tom Dawson; X Li; Lee M Graves; R Dy
Angiotensin II activates at least two tyrosine kinases in rat liver epithelial cells. Separation of the major calcium-regulated tyrosine kinase from p125FAK.
The Journal of biological chemistry 1995;270(47):28440-7.
1995: I E Zohn; H Yu; X Li; Adrienne D Cox; Henry Earp
Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase.
Molecular and cellular biology 1995;15(11):6160-8.
1995: William E Miller; Henry Earp; Nancy Raab-Traub
The Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor.
Journal of virology 1995;69(7):4390-8.
1995: Henry Earp; Tom Dawson; X Li; H Yu
Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research.
Breast cancer research and treatment 1995;35(1):115-32.
1995: Douglas K. Graham; G W Bowman; Tom Dawson; William L Stanford; Henry Earp; H R Snodgrass
Cloning and developmental expression analysis of the murine c-mer tyrosine kinase.
Oncogene 1995;10(12):2349-59.
1995: S K Duddy; Henry Earp; W E Russell; Gary J Smith; Joe W Grisham
Differential dependence of the tumorigenicity of chemically transformed rat liver epithelial cells on autocrine production of transforming growth factor alpha.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(3):251-61.
1994: Douglas K. Graham; Tom Dawson; D L Mullaney; H R Snodgrass; Henry Earp
Cloning and mRNA expression analysis of a novel human protooncogene, c-mer.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(6):647-57.
1994: N C Luetteke; H K Phillips; T H Qiu; Neal G Copeland; Henry Earp; Nancy A Jenkins; David C Lee
The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase.
Genes & development 1994;8(4):399-413.
1994: W R Huckle; Henry Earp
Synergistic activation of tyrosine phosphorylation by o-vanadate plus calcium ionophore A23187 or aromatic 1,2-diols.
Biochemistry 1994;33(6):1518-25.
1994: W R Huckle; Henry Earp
Regulation of cell proliferation and growth by angiotensin II.
Progress in growth factor research 1994;5(2):177-94.
1992: L Kornberg; Henry Earp; Thomas J Parsons; Michael D Schaller; Rudy L Juliano
Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase.
The Journal of biological chemistry 1992;267(33):23439-42.
1992: W R Huckle; R C Dy; Henry Earp
Calcium-dependent increase in tyrosine kinase activity stimulated by angiotensin II.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(18):8837-41.
1992: Pamela Diliberto; Gerald Gordon; C L Yu; Henry Earp; Brian Herman
Platelet-derived growth factor (PDGF) alpha receptor activation modulates the calcium mobilizing activity of the PDGF beta receptor in Balb/c3T3 fibroblasts.
The Journal of biological chemistry 1992;267(17):11888-97.
1992: Balázs Sarkadi; D Bauzon; W R Huckle; Henry Earp; A Berry; H Suchindran; E M Price; J C Olson; Richard C Boucher; Gene A Scarborough
Biochemical characterization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis epithelial cells.
The Journal of biological chemistry 1992;267(3):2087-95.
1991: L J Kornberg; Henry Earp; C E Turner; C Prockop; Rudy L Juliano
Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8392-6.
1991: L W Lee; V W Raymond; Ming Tsao; D C Lee; Henry Earp; Joe W Grisham
Clonal cosegregation of tumorigenicity with overexpression of c-myc and transforming growth factor alpha genes in chemically transformed rat liver epithelial cells.
Cancer research 1991;51(19):5238-44.
1991: John P O'Bryan; R A Frye; Patricia C Cogswell; A Neubauer; B Kitch; C Prokop; R Espinosa; Michelle M Le Beau; Henry Earp; Edison Liu
axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.
Molecular and cellular biology 1991;11(10):5016-31.
1991: S Takahashi; M Conti; C Prokop; Judson Vanwyk; Henry Earp
Thyrotropin and insulin-like growth factor I regulation of tyrosine phosphorylation in FRTL-5 cells. Interaction between cAMP-dependent and growth factor-dependent signal transduction.
The Journal of biological chemistry 1991;266(12):7834-41.
1991: P C Ferriola; Henry Earp; R Di Augustine; Paul Nettesheim
Role of TGF alpha and its receptor in proliferation of immortalized rat tracheal epithelial cells: studies with tyrphostin and TGF alpha antisera.
Journal of cellular physiology 1991;147(1):166-75.
1990: W R Huckle; J R Hepler; S G Rhee; T Kendall Harden; Henry Earp
Protein kinase C inhibits epidermal growth factor-dependent tyrosine phosphorylation of phospholipase C gamma and activation of phosphoinositide hydrolysis.
Endocrinology 1990;127(4):1697-705.
1990: V W Raymond; Joe W Grisham; Henry Earp
Characterization of epidermal growth factor receptor induction by retinoic acid in a chemically transformed rat liver cell line.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1990;1(9):393-9.
1990: J R Hepler; R A Jeffs; W R Huckle; H E Outlaw; S G Rhee; Henry Earp; T Kendall Harden
Evidence that the epidermal growth factor receptor and non-tyrosine kinase hormone receptors stimulate phosphoinositide hydrolysis by independent pathways.
The Biochemical journal 1990;270(2):337-44.
1990: B K McCune; C A Prokop; Henry Earp
Transient epidermal growth factor (EGF)-dependent suppression of EGF receptor autophosphorylation during internalization.
The Journal of biological chemistry 1990;265(17):9715-21.
1990: L A Petch; J Harris; V W Raymond; A Blasband; D C Lee; Henry Earp
A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue.
Molecular and cellular biology 1990;10(6):2973-82.
1990: Joe W Grisham; M S Tsao; D C Lee; Henry Earp
Sequential changes in epidermal growth factor receptor/ligand function in cultured rat liver epithelial cells transformed chemically in vitro.
Pathobiology : journal of immunopathology, molecular and cellular biology 1990;58(1):3-14.
1989: T Katagiri; Jenny P-Y Ting; R Dy; C Prokop; P Cohen; Henry Earp
Tyrosine phosphorylation of a c-Src-like protein is increased in membranes of CD4- CD8- T lymphocytes from lpr/lpr mice.
Molecular and cellular biology 1989;9(11):4914-22.
1989: Richard C Boucher; E H Cheng; Anthony M Paradiso; Monroe Stutts; Michael Knowles; Henry Earp
Chloride secretory response of cystic fibrosis human airway epithelia. Preservation of calcium but not protein kinase C- and A-dependent mechanisms.
The Journal of clinical investigation 1989;84(5):1424-31.
1989: B K McCune; Henry Earp
The epidermal growth factor receptor tyrosine kinase in liver epithelial cells. The effect of ligand-dependent changes in cellular location.
The Journal of biological chemistry 1989;264(26):15501-7.
1989: V W Raymond; D C Lee; Joe W Grisham; Henry Earp
Regulation of transforming growth factor alpha messenger RNA expression in a chemically transformed rat hepatic epithelial cell line by phorbol ester and hormones.
Cancer research 1989;49(13):3608-12.
1989: M Zagari; M Stephens; Henry Earp; Brian Herman
Relationship of cytosolic ion fluxes and protein kinase C activation to platelet-derived growth factor induced competence and growth in BALB/c-3T3 cells.
Journal of cellular physiology 1989;139(1):167-74.
1989: S T Wong; L F Winchell; B K McCune; Henry Earp; J Teixidó; J Massagué; Brian Herman; David C Lee
The TGF-alpha precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction.
Cell 1989;56(3):495-506.
1989: P C Ferriola; C Walker; A T Robertson; Henry Earp; D W Rusnak; Paul Nettesheim
Altered growth factor dependence and transforming growth factor gene expression in transformed rat tracheal epithelial cells.
Molecular carcinogenesis 1989;2(6):336-44.
1988: D K Ways; R C Dodd; T E Bennett; J L Hooker; Henry Earp
Effect of retinoic acid on phorbol ester-stimulated differentiation and protein kinase C-dependent phosphorylation in the U937 human monoblastoid cell.
Cancer research 1988;48(20):5779-87.
1988: Henry Earp; J R Hepler; L A Petch; A Miller; A R Berry; J Harris; V W Raymond; B K McCune; L W Lee; Joe W Grisham
Epidermal growth factor (EGF) and hormones stimulate phosphoinositide hydrolysis and increase EGF receptor protein synthesis and mRNA levels in rat liver epithelial cells. Evidence for protein kinase C-dependent and -independent pathways.
The Journal of biological chemistry 1988;263(27):13868-74.
1988: J R Hepler; Henry Earp; T Kendall Harden
Long-term phorbol ester treatment down-regulates protein kinase C and sensitizes the phosphoinositide signaling pathway to hormone and growth factor stimulation. Evidence for a role of protein kinase C in agonist-induced desensitization.
The Journal of biological chemistry 1988;263(16):7610-9.
1987: D K Ways; R C Dodd; T E Bennett; T K Gray; Henry Earp
1,25-Dihydroxyvitamin D3 enhances phorbol ester-stimulated differentiation and protein kinase C-dependent substrate phosphorylation activity in the U937 human monoblastoid cell.
Endocrinology 1987;121(5):1654-61.
1987: D K Ways; R C Dodd; Henry Earp
Dissimilar effects of phorbol ester and diacylglycerol derivative on protein kinase activity in the monoblastoid U937 cell.
Cancer research 1987;47(13):3344-50.
1987: M S Tsao; J Blaisdell; B B Chou; Henry Earp; Joe W Grisham
Inconsistent effects of all-trans retinoic acid on different clones of chemically transformed rat liver epithelial cells.
Carcinogenesis 1987;8(4):497-501.
1987: J R Hepler; N Nakahata; T W Lovenberg; J DiGuiseppi; Brian Herman; Henry Earp; T Kendall Harden
Epidermal growth factor stimulates the rapid accumulation of inositol (1,4,5)-trisphosphate and a rise in cytosolic calcium mobilized from intracellular stores in A431 cells.
The Journal of biological chemistry 1987;262(7):2951-6.
1986: D K Ways; R C Dodd; J T Gwynne; Henry Earp
Lipoprotein modulation of the intracellular localization of protein kinase C and alteration of phorbol ester-stimulated differentiation in the human monoblastic U937 cell line.
Cancer research 1986;46(12 Pt 1):6049-53.
1986: B O Fanger; K S Austin; Henry Earp; J A Cidlowski
Cross-linking of epidermal growth factor receptors in intact cells: detection of initial stages of receptor clustering and determination of molecular weight of high-affinity receptors.
Biochemistry 1986;25(21):6414-20.
1986: Henry Earp; K S Austin; J Blaisdell; R A Rubin; K G Nelson; L W Lee; Joe W Grisham
Epidermal growth factor (EGF) stimulates EGF receptor synthesis.
The Journal of biological chemistry 1986;261(11):4777-80.
1986: M S Tsao; Henry Earp; Joe W Grisham
The effects of epidermal growth factor and the state of confluence on enzymatic activities of cultured rat liver epithelial cells.
Journal of cellular physiology 1986;126(2):167-73.
1985: M S Tsao; Henry Earp; Joe W Grisham
Gradation of carcinogen-induced capacity for anchorage-independent growth in cultured rat liver epithelial cells.
Cancer research 1985;45(9):4428-32.
1985: Henry Earp; K S Austin; G Y Gillespie; S C Buessow; A A Davies; P J Parker
Characterization of distinct tyrosine-specific protein kinases in B and T lymphocytes.
The Journal of biological chemistry 1985;260(7):4351-6.
1984: V L Davis; Henry Earp; D A Stempel
Interferon inhibits agonist-induced cyclic AMP accumulation in human lymphocytes.
The American review of respiratory disease 1984;130(2):167-70.
1984: Q Lin; J Blaisdell; E O'Keefe; Henry Earp
Insulin inhibits the glucocorticoid-mediated increase in hepatocyte EGF binding.
Journal of cellular physiology 1984;119(3):267-72.
1984: Henry Earp; K S Austin; S C Buessow; R Dy; G Y Gillespie
Membranes from T and B lymphocytes have different patterns of tyrosine phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(8):2347-51.
1984: W R Rackoff; R A Rubin; Henry Earp
Phosphorylation of the hepatic EGF receptor with cAMP-dependent protein kinase.
Molecular and cellular endocrinology 1984;34(2):113-9.
1984: Henry Earp; Q Lin; J Blaisdell
Dimethyl sulfoxide decreases specific EGF binding.
Journal of cellular biochemistry 1984;26(4):221-30.
1983: Henry Earp; R A Rubin; K S Austin; R C Dy
Vanadate stimulates tyrosine phosphorylation of two proteins in Raji human lymphoblastoid cell membranes.
FEBS letters 1983;161(2):180-4.
1983: S Jacobs; F C Kull; Henry Earp; M E Svoboda; Judson Vanwyk; P Cuatrecasas
Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor.
The Journal of biological chemistry 1983;258(16):9581-4.
1983: Henry Earp; R A Rubin; K S Austin; R C Dy
DMSO increases tyrosine residue phosphorylation in membranes from murine erythroleukemia cells.
Biochemical and biophysical research communications 1983;112(2):413-8.
1983: R A Rubin; Henry Earp
Solubilization of EGF receptor with Triton X-100 alters stimulation of tyrosine residue phosphorylation by EGF and dimethyl sulfoxide.
The Journal of biological chemistry 1983;258(8):5177-82.
1983: R A Rubin; Henry Earp
Dimethyl sulfoxide stimulates tyrosine residue phosphorylation of rat liver epidermal growth factor receptor.
Science (New York, N.Y.) 1983;219(4580):60-3.
1982: W Wharton; Edward B Leof; N Olashaw; Henry Earp; Warren Pledger
Increases in cyclic AMP potentiate competence formation in BALB/c-3T3 cells.
Journal of cellular physiology 1982;111(2):201-6.
1982: R A Rubin; E J O'Keefe; Henry Earp
Alteration of epidermal growth factor-dependent phosphorylation during rat liver regeneration.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(3):776-80.
1981: Henry Earp; E J O'Keefe
Epidermal growth factor receptor number decreases during rat liver regeneration.
The Journal of clinical investigation 1981;67(5):1580-3.
1980: Henry Earp
The role of insulin, glucagon, and cAMP in the regulation of hepatocyte guanylate cyclase activity.
The Journal of biological chemistry 1980;255(19):8979-82.
1980: Henry Earp; W A Spruill; J Aghajanian; A L Steiner
Guanylate cyclase activity in testicular growth and development, injury, and atrophy.
Advances in cyclic nucleotide research 1980;12():347-58.
1979: W A Spruill; A L Steiner; Henry Earp
Characterization of rat testicular guanylate cyclase during development.
Biochimica et biophysica acta 1979;587(4):484-94.
1979: S N Levine; A L Steiner; Henry Earp; Gerhard Meissner
Particulate guanylate cyclase of skeletal muscle: effects of Ca2+ and other divalent cations on enzyme activity.
Biochimica et biophysica acta 1979;566(1):171-82.
1978: W A Spruill; A L Steiner; Henry Earp
Tissue guanosine-3',5'-cyclic monophosphate levels and soluble guanylate cyclase activity: a positive correlation during unilateral cryptorchidism in the rat testis.
The Journal of clinical investigation 1978;62(3):568-76.
1978: Y Koide; Henry Earp; S H Ong; A L Steiner
Alterations in the intracellular distribution of cGMP and guanylate cyclase activity during rat liver regeneration.
The Journal of biological chemistry 1978;253(12):4439-45.
1978: A L Steiner; Y Koide; Henry Earp; P J Bechtel; J A Beavo
Compartmentalization of cyclic nucleotides and cyclic AMP-dependent protein kinases in rat liver: immunocytochemical demonstration.
Advances in cyclic nucleotide research 1978;9():691-705.
1978: Henry Earp; A L Steiner
Compartmentalization of cyclic nucleotide-mediated hormone action.
Annual review of pharmacology and toxicology 1978;18():431-59.
1977: Henry Earp; P D Utsinger; William Yount; M Logue; A L Steiner
Lymphocyte surface modulation and cyclic nucleotides I. Topographic correlation of cyclic adenosine 3':5'-monophosphate and immunoglobulin immunofluorescence during lymphocyte capping.
The Journal of experimental medicine 1977;145(4):1087-92.
1977: Henry Earp; P Smith; S H Huang Ong; A L Steiner
Regulation of hepatic nuclear guanylate cyclase.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(3):946-50.
1975: Henry Earp
Alterations in hepatic chromatin template availability during infection.
The American journal of physiology 1975;228(4):1183-7.
1974: Henry Earp
Glucocorticoid regulation of transcription: the role of physiologic concentrations of adrenal glucocorticoids in the diurnal variation of rat liver chromatin template availability.
Biochimica et biophysica acta 1974;340(1):95-107.
1970: Henry Earp; R L Ney; H J Gitelman; R Richman; H F DeLuca
Effects of 25-hydroxycholecalciferol in patients with familial hypophosphatemia and vitamin-D-resistant rickets.
The New England journal of medicine 1970;283(12):627-30.
1970: Henry Earp; B S Watson; R L Ney
Adenosine 3',5'-monophosphate as the mediator of ACTH-induced ascorbic acid depletion in the rat adrenal.
Endocrinology 1970;87(1):118-23.