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Frank Birklein

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Rolf-Detlef Treede; T Wagner; Gunnar Wasner; G Arendt; Frank Birklein; T Cegla; Rainer Freynhagen; H-H Gockel; M-L Heskamp; I W Husstedt; H Jager; R Joppich; K-U Kern; A Leffler; Christoph Maier; H-H Nagelein; Roman Rolke; S Seddigh; Claudia Sommer; S Stander; R Baron
Mechanism- and experience-based strategies to optimize treatment response to the capsaicin 8% cutaneous patch in patients with localized neuropathic pain.
Tanja Schlereth; Nicolas Werner; Markus Breimhorst; Peter D Drummond; Katrin Pottschmidt; Frank Birklein
Inhibition of neuropeptide degradation suppresses sweating but increases the area of the axon reflex flare.
Uwe Kern; Matthias Kohl; Ruben Müller; Volker Busch; Frank Birklein
Phantom limb pain in daily practice--still a lot of work to do!

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2013: Rolf-Detlef Treede; T Wagner; Gunnar Wasner; G Arendt; Frank Birklein; T Cegla; Rainer Freynhagen; H-H Gockel; M-L Heskamp; I W Husstedt; H Jager; R Joppich; K-U Kern; A Leffler; Christoph Maier; H-H Nagelein; Roman Rolke; S Seddigh; Claudia Sommer; S Stander; R Baron
Mechanism- and experience-based strategies to optimize treatment response to the capsaicin 8% cutaneous patch in patients with localized neuropathic pain.
Current medical research and opinion 2013;29(5):527-38.
2013: Tanja Schlereth; Nicolas Werner; Markus Breimhorst; Peter D Drummond; Katrin Pottschmidt; Frank Birklein
Inhibition of neuropeptide degradation suppresses sweating but increases the area of the axon reflex flare.
Experimental dermatology 2013;22(4):299-301.
2012: Uwe Kern; Matthias Kohl; Ruben Müller; Volker Busch; Frank Birklein
Phantom limb pain in daily practice--still a lot of work to do!
Pain medicine (Malden, Mass.) 2012;13(12):1611-26.
2012: Marcus Schley; N Sjögren; P J Albrecht; A Bayram; Justus Benrath; Frank Birklein; M Dusch; C Geber; L Gee; B Hägglöf; Christoph Konrad; F L Rice; Roman Rukwied; Martin Schmelz
Skin innervation at different depths correlates with small fibre function but not with pain in neuropathic pain patients.
European journal of pain (London, England) 2012;16(10):1414-25.
2012: M Breimhorst; M Hondrich; A May; C Rebhorn; Frank Birklein
Sensory and sympathetic correlates of heat pain sensitization and habituation in men and women.
European journal of pain (London, England) 2012;16(9):1281-92.
2012: Cora Rebhorn; Clemens Vogel; Frank Birklein; Markus Breimhorst; Diana Buniatyan; Thomas Eberle
The efficacy of acupuncture in human pain models: a randomized, controlled, double-blinded study.
Pain 2012;153(9):1852-62.
2012: Frank Birklein; Christian Maihöfner
Neglect your back to control your pain?
Neurology 2012;79(4):300-1.
2012: Doreen B Pfau; Frank Birklein; Christian Geber; Rolf-Detlef Treede
Quantitative sensory testing of neuropathic pain patients: potential mechanistic and therapeutic implications.
Current pain and headache reports 2012;16(3):199-206.
2012: Tanja Schlereth; Frank Birklein
Mast cells: source of inflammation in complex regional pain syndrome?
Anesthesiology 2012;116(4):756-7.
2012: A May; R Rodriguez-Raecke; A Schulte; Frank Birklein; M Breimhorst; K Ihle; T P Jürgens
Within-session sensitization and between-session habituation: a robust physiological response to repetitive painful heat stimulation.
European journal of pain (London, England) 2012;16(3):401-9.
2012: Wolfgang Freund; Christian Gaser; Georg Grön; Markus Juchems; Marguerite Müller; Bernd L Schmitz; Christian Billich; Frank Birklein; Sonja Faust; Arthur P Wunderlich; Uwe H Schütz
Substantial and reversible brain gray matter reduction but no acute brain lesions in ultramarathon runners: experience from the TransEurope-FootRace Project.
BMC medicine 2012;10():170.
2012: Marcel Fechir; C Geber; S Kritzmann; Tanja Schlereth; B Baier; M Breimhorst; Frank Birklein
Naloxone inhibits not only stress-induced analgesia but also sympathetic activation and baroreceptor-reflex sensitivity.
European journal of pain (London, England) 2012;16(1):82-92.
2011: Danielle Kohr; Wolfgang Kummer; Ervice Pouokam; Pratibha Singh; Marlene Tschernatsch; Angela Vincent; Gerd Wallukat; Frank Birklein; Martin Diener; Andreas Goebel; Manfred Kaps; Franz Blaes
Autoimmunity against the β2 adrenergic receptor and muscarinic-2 receptor in complex regional pain syndrome.
Pain 2011;152(12):2690-700.
2011: Johan Marinus; G Lorimer Moseley; Ralf Baron; Frank Birklein; Wade S Kingery; Christian Maihöfner; Jacobus J van Hilten
Clinical features and pathophysiology of complex regional pain syndrome.
Lancet neurology 2011;10(7):637-48.
2011: Christian Geber; Ulf Baumgärtner; Marcel Fechir; Thomas Vogt; Frank Birklein; Rolf-Detlef Treede
Comparison of LEP and QST and their contribution to standard sensory diagnostic assessment of spinal lesions: a pilot study.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2011;32(3):401-10.
2011: Beril Doganci; Markus Breimhorst; Marie Hondrich; Rea Rodriguez-Raecke; Arne May; Frank Birklein
Expectations modulate long-term heat pain habituation.
European journal of pain (London, England) 2011;15(4):384-8.
2011: Christian Geber; Thomas Klein; Shahnaz Azad; Frank Birklein; Janne Gierthmühlen; Volker Huge; Meike Lauchart; Dorothee Nitzsche; Maike Stengel; Michael Valet; Ralf Baron; Christoph Maier; Thomas R Tölle; Rolf-Detlef Treede
Test-retest and interobserver reliability of quantitative sensory testing according to the protocol of the German Research Network on Neuropathic Pain (DFNS): a multi-centre study.
Pain 2011;152(3):548-56.
2011: Heidrun H Krämer; Thomas Eberle; Nurcan Üçeyler; Ina Wagner; Thomas Klonschinsky; Lars Peter Müller; Claudia Sommer; Frank Birklein
TNF-α in CRPS and 'normal' trauma--significant differences between tissue and serum.
Pain 2011;152(2):285-90.
2011: Claudia Sommer; Frank Birklein
Resolvins and inflammatory pain.
F1000 medicine reports 2011;3():19.
2011: Markus Breimhorst; Stephan Sandrock; Marcel Fechir; Nadine Hausenblas; Christian Geber; Frank Birklein
Do intensity ratings and skin conductance responses reliably discriminate between different stimulus intensities in experimentally induced pain?
The journal of pain : official journal of the American Pain Society 2011;12(1):61-70.
2010: Robert Harden; Stephen Bruehl; R S G M Perez; Frank Birklein; Johan Marinus; Christian Maihofner; Timothy Lubenow; Asokumar Buvanendran; Sean Mackey; Joseph Graciosa; Mila Mogilevski; Christopher Ramsden; Tanja Schlereth; Melissa Chont; Jean-Jacques Vatine
Development of a severity score for CRPS.
Pain 2010;151(3):870-6.
2010: D Fuchs; Frank Birklein; Peter W Reeh; Susanne K Sauer
Sensitized peripheral nociception in experimental diabetes of the rat.
Pain 2010;151(2):496-505.
2010: Sigrid G L Fischer; W W A Zuurmond; Frank Birklein; Stephan A Loer; R S G M Perez
Anti-inflammatory treatment of Complex Regional Pain Syndrome.
Pain 2010;151(2):251-6.
2010: Bernhard Baier; Hans-Otto Karnath; Frank Thömke; Frank Birklein; Notger Müller; Marianne Dieterich
Is there a link between spatial neglect and vestibular function at the cerebellar level?
Journal of neurology 2010;257(9):1579-81.
2010: Rea Rodriguez-Raecke; Beril Doganci; Markus Breimhorst; Anne Stankewitz; Christian Büchel; Frank Birklein; Arne May
Insular cortex activity is associated with effects of negative expectation on nociceptive long-term habituation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(34):11363-8.
2010: Robert Harden; Stephen Bruehl; Roberto S G M Perez; Frank Birklein; Johan Marinus; Christian Maihofner; Timothy Lubenow; Asokumar Buvanendran; Sean Mackey; Joseph Graciosa; Mila Mogilevski; Christopher Ramsden; Melissa Chont; Jean-Jacques Vatine
Validation of proposed diagnostic criteria (the "Budapest Criteria") for Complex Regional Pain Syndrome.
Pain 2010;150(2):268-74.
2010: C Geber; Frank Birklein
Dissecting post-herniotomy pain--scratching the surface?
Pain 2010;150(2):215-6.
2010: Bernhard Baier; Hans-Otto Karnath; Marianne Dieterich; Frank Birklein; Carolin Heinze; Notger G Müller
Keeping memory clear and stable--the contribution of human basal ganglia and prefrontal cortex to working memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(29):9788-92.
2010: A Klega; Thomas Eberle; Hans-Georg Buchholz; S Maus; Christian Maihöfner; Mathias Schreckenberger; Frank Birklein
Central opioidergic neurotransmission in complex regional pain syndrome.
Neurology 2010;75(2):129-36.
2010: Marcel Fechir; A Klega; H G Buchholz; N Pfeifer; S Balon; Tanja Schlereth; C Geber; M Breimhorst; C Maihöfner; Frank Birklein; M Schreckenberger
Cortical control of thermoregulatory sympathetic activation.
The European journal of neuroscience 2010;31(11):2101-11.
2010: Claudia Sommer; Frank Birklein
Fighting off pain with resolvins.
Nature medicine 2010;16(5):518-20.
2010: Stefan Leis; Nicola Meyer; Andreas Bickel; Christoph H Schick; Sophie Krüger; Martin Schmelz; Frank Birklein
Thoracoscopic sympathectomy at the T2 or T3 level facilitates bradykinin-induced protein extravasation in human forearm skin.
Pain medicine (Malden, Mass.) 2010;11(5):774-80.
2010: Marcel Fechir; Matthias Gamer; I Blasius; Thomas Bauermann; M Breimhorst; Peter Schlindwein; Tanja Schlereth; Frank Birklein
Functional imaging of sympathetic activation during mental stress.
NeuroImage 2010;50(2):847-54.
2010: Bernhard Baier; Sandra Bense; Frank Birklein; Hans-Georg Buchholz; Anja Mischke; Mathias Schreckenberger; Marianne Dieterich
Evidence for modulation of opioidergic activity in central vestibular processing: A [(18)F] diprenorphine PET study.
Human brain mapping 2010;31(4):550-5.
2010: Kathrin Huehne; Ute Schaal; Stefan Leis; Steffen Uebe; M Florencia Gosso; Arn van den Maagdenberg; Christian Maihöfner; Frank Birklein; Bernd Rautenstrauss; Andreas Winterpacht
Lack of genetic association of neutral endopeptidase (NEP) with complex regional pain syndrome (CRPS).
Neuroscience letters 2010;472(1):19-23.
2010: Bernhard Baier; Marianne Dieterich; Peter Stoeter; Frank Birklein; Notger G Müller
Anatomical correlate of impaired covert visual attentional processes in patients with cerebellar lesions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(10):3770-6.
2010: Frank Birklein; Claudia Sommer
Intravenous immunoglobulin to fight complex regional pain syndromes: hopes and doubts.
Annals of internal medicine 2010;152(3):188-9.
2010: B Baier; B de Haan; N Mueller; Frank Thoemke; Frank Birklein; Marianne Dieterich; H-O Karnath
Anatomical correlate of positive spontaneous visual phenomena: a voxelwise lesion study.
Neurology 2010;74(3):218-22.
2010: Ana Paula Barreiros; Christian Geber; Frank Birklein; Peter R Galle; Gerd Otto
Clinical symptomatic de novo systemic transthyretin amyloidosis 9 years after domino liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2010;16(1):109.
2010: Thomas Eberle; B Doganci; Heidrun H Krämer; Marcel Fechir; I Wagner; Clemens Sommer; Frank Birklein
Mechanical but not painful electrical stimuli trigger TNF alpha release in human skin.
Experimental neurology 2010;221(1):246-50.
2010: Christina Mueller; André Klega; Hans-Georg Buchholz; Roman Rolke; Walter Magerl; Ralf Schirrmacher; Esther Schirrmacher; Frank Birklein; Rolf-Detlef Treede; Mathias Schreckenberger
Basal opioid receptor binding is associated with differences in sensory perception in healthy human subjects: a [18F]diprenorphine PET study.
NeuroImage 2010;49(1):731-7.
2009: Felix Luessi; Janina Sollors; Harald Müller; Peter Stoeter; Clemens Sommer; Thomas Vogt; Frank Birklein; Frank Thömke
Infliximab in the treatment of rheumatoid meningoencephalitis.
Journal of neurology 2009;256(12):2094-6.
2009: Christian Geber; Ulf Baumgärtner; Rainer Schwab; Harald Müller; Peter Stoeter; Marianne Dieterich; Clemens Sommer; Frank Birklein; Rolf-Detlef Treede
Revised definition of neuropathic pain and its grading system: an open case series illustrating its use in clinical practice.
The American journal of medicine 2009;122(10 Suppl):S3-12.
2009: Marcel Fechir; Tanja Schlereth; S Kritzmann; S Balon; N Pfeifer; C Geber; M Breimhorst; Thomas Eberle; Matthias Gamer; Frank Birklein
Stress and thermoregulation: different sympathetic responses and different effects on experimental pain.
European journal of pain (London, England) 2009;13(9):935-41.
2009: Heidrun H Krämer; Lan He; Bao Lu; Frank Birklein; Claudia Sommer
Increased pain and neurogenic inflammation in mice deficient of neutral endopeptidase.
Neurobiology of disease 2009;35(2):177-83.
2009: Danielle Kohr; Marlene Tschernatsch; Katrin Schmitz; Pratibha Singh; Manfred Kaps; Karl-Herbert Schäfer; Martin Diener; Janina Mathies; Oliver Matz; Wolfgang Kummer; Christian Maihöfner; Thorsten Fritz; Frank Birklein; Franz Blaes
Autoantibodies in complex regional pain syndrome bind to a differentiation-dependent neuronal surface autoantigen.
Pain 2009;143(3):246-51.
2009: H H F Jantsch; M Gawlitza; C Geber; Ulf Baumgärtner; Heidrun H Krämer; Walter Magerl; Rolf-Detlef Treede; Frank Birklein
Explicit episodic memory for sensory-discriminative components of capsaicin-induced pain: immediate and delayed ratings.
Pain 2009;143(1-2):97-105.
2009: Thomas Eberle; B Doganci; Heidrun H Krämer; C Geber; Marcel Fechir; Walter Magerl; Frank Birklein
Warm and cold complex regional pain syndromes: differences beyond skin temperature?
Neurology 2009;72(6):505-12.
2009: Tanja Schlereth; Marianne Dieterich; Frank Birklein
Hyperhidrosis--causes and treatment of enhanced sweating.
Deutsches Ärzteblatt international 2009;106(3):32-7.
2009: B Arneth; Frank Birklein
High sensitivity of free lambda and free kappa light chains for detection of intrathecal immunoglobulin synthesis in cerebrospinal fluid.
Acta neurologica Scandinavica 2009;119(1):39-44.
2008: Peter Schlindwein; Hans-Georg Buchholz; Mathias Schreckenberger; Peter Bartenstein; Marianne Dieterich; Frank Birklein
Sympathetic activity at rest and motor brain areas: FDG-PET study.
Autonomic neuroscience : basic & clinical 2008;143(1-2):27-32.
2008: Christian Geber; Walter Magerl; Ricarda Fondel; Marcel Fechir; Roman Rolke; Thomas Vogt; Rolf-Detlef Treede; Frank Birklein
Numbness in clinical and experimental pain--a cross-sectional study exploring the mechanisms of reduced tactile function.
Pain 2008;139(1):73-81.
2008: Frank Birklein; C Depmeier; Roman Rolke; C Hansen; B Rautenstrauss; Dirk Prawitt; Walter Magerl
A family-based investigation of cold pain tolerance.
Pain 2008;138(1):111-8.
2008: Frank Birklein; Martin Schmelz
Neuropeptides, neurogenic inflammation and complex regional pain syndrome (CRPS).
Neuroscience letters 2008;437(3):199-202.
2008: Marcel Fechir; Christian Geber; Frank Birklein
Evolving understandings about complex regional pain syndrome and its treatment.
Current pain and headache reports 2008;12(3):186-91.
2008: Heidrun H Krämer; Christian Stenner; Susann Seddigh; Thomas Bauermann; Frank Birklein; Christian Maihöfner
Illusion of pain: pre-existing knowledge determines brain activation of 'imagined allodynia'.
The journal of pain : official journal of the American Pain Society 2008;9(6):543-51.
2008: Lorimer Moseley; Nadia Zalucki; Frank Birklein; Johan Marinus; Jacobus J van Hilten; hannu luomajoki
Thinking about movement hurts: the effect of motor imagery on pain and swelling in people with chronic arm pain.
Arthritis and rheumatism 2008;59(5):623-31.
2008: A Lingawi; Martin Henri Hessmann; Frank Birklein; Alexander Hofmann; P Ingelfinger; Pol Maria Rommens
[Complex regional pain syndrome. A rare complication after acetabular fracture].
Der Unfallchirurg 2008;111(3):197-200.
2008: Marcel Fechir; Tanja Schlereth; T Purat; S Kritzmann; C Geber; Thomas Eberle; Matthias Gamer; Frank Birklein
Patterns of sympathetic responses induced by different stress tasks.
The open neurology journal 2008;2():25-31.
2008: Tanja Schlereth; Frank Birklein
The sympathetic nervous system and pain.
Neuromolecular medicine 2008;10(3):141-7.
2008: Heidrun H Krämer; Susann Seddigh; G Lorimer Moseley; Frank Birklein
Dysynchiria is not a common feature of neuropathic pain.
European journal of pain (London, England) 2008;12(1):128-31.
2007: Heidrun H Krämer; Linda Lundblad; Frank Birklein; Mattias Linde; Tomas Karlsson; Mikael Elam; Håkan Olausson
Activation of the cortical pain network by soft tactile stimulation after injection of sumatriptan.
Pain 2007;133(1-3):72-8.
2007: Nurcan Üçeyler; Tatiana Eberle; Roman Rolke; Frank Birklein; Claudia Sommer
Differential expression patterns of cytokines in complex regional pain syndrome.
Pain 2007;132(1-2):195-205.
2007: Michael Bernateck; Roman Rolke; Frank Birklein; Rolf-Detlef Treede; Matthias Fink; Matthias Karst
Successful intravenous regional block with low-dose tumor necrosis factor-alpha antibody infliximab for treatment of complex regional pain syndrome 1.
Anesthesia and analgesia 2007;105(4):1148-51, table of contents.
2007: Christian Maihöfner; Ralf Baron; Roberto DeCol; Andreas Binder; Frank Birklein; Günther Deuschl; Hermann O Handwerker; Jörn Schattschneider
The motor system shows adaptive changes in complex regional pain syndrome.
Brain : a journal of neurology 2007;130(Pt 10):2671-87.
2007: Franz Blaes; Marlene Tschernatsch; M E Braeu; O Matz; K Schmitz; D Nascimento; Manfred Kaps; Frank Birklein
Autoimmunity in complex-regional pain syndrome.
Annals of the New York Academy of Sciences 2007;1107():168-73.
2007: Christian Maihöfner; Frank Birklein
[Complex regional pain syndromes: new aspects on pathophysiology and therapy].
Fortschritte der Neurologie-Psychiatrie 2007;75(6):331-42.
2007: Christian Geber; Ricarda Fondel; Heidrun H Krämer; Roman Rolke; Rolf-Detlef Treede; Claudia Sommer; Frank Birklein
Psychophysics, flare, and neurosecretory function in human pain models: capsaicin versus electrically evoked pain.
The journal of pain : official journal of the American Pain Society 2007;8(6):503-14.
2007: Tanja Schlereth; Sonja Schönefeld; Frank Birklein; Charles James Kirkpatrick; Ignaz Wessler
In vivo release of non-neuronal acetylcholine from human skin by dermal microdialysis: effects of sunlight, UV-A and tactile stimulus.
Life sciences 2007;80(24-25):2239-42.
2007: Oliver Gross; Marlene Tschernatsch; Michael E Bräu; Gunter Hempelmann; Frank Birklein; Manfred Kaps; Katharina Madlener; Franz Blaes
Increased seroprevalence of parvovirus B 19 IgG in complex regional pain syndrome is not associated with antiendothelial autoimmunity.
European journal of pain (London, England) 2007;11(2):237-40.
2006: Frank Birklein; Christian Maihöfner
Use your imagination: training the brain and not the body to improve chronic pain and restore function.
Neurology 2006;67(12):2115-6.
2006: Tanja Schlereth; Jan Oliver Dittmar; Bianca Seewald; Frank Birklein
Peripheral amplification of sweating--a role for calcitonin gene-related peptide.
The Journal of physiology 2006;576(Pt 3):823-32.
2006: Roman Rolke; R Baron; Christoph Maier; Thomas R Tölle; Rolf-Detlef Treede; Antje Beyer; Andreas Binder; N Birbaumer; Frank Birklein; I C Bötefür; S Braune; H Flor; Volker Huge; R Klug; G B Landwehrmeyer; Walter Magerl; Christian Maihöfner; C Rolko; C Schaub; A Scherens; Till Sprenger; Michael Valet; B Wasserka
Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): standardized protocol and reference values.
Pain 2006;123(3):231-43.
2006: Annette Kirchner; Hermann Stefan; Katrin Bastian; Frank Birklein
Vagus nerve stimulation suppresses pain but has limited effects on neurogenic inflammation in humans.
European journal of pain (London, England) 2006;10(5):449-55.
2006: Christian Maihöfner; Bernhard Neundörfer; Frank Birklein; Hermann O Handwerker
Mislocalization of tactile stimulation in patients with complex regional pain syndrome.
Journal of neurology 2006;253(6):772-9.
2006: Heidrun H Krämer; Katharina Schmidt; Stefan Leis; Martin Schmelz; Claudia Sommer; Frank Birklein
Angiotensin converting enzyme has an inhibitory role in CGRP metabolism in human skin.
Peptides 2006;27(4):917-20.
2006: Christian Maihöfner; Hermann O Handwerker; Frank Birklein
Functional imaging of allodynia in complex regional pain syndrome.
Neurology 2006;66(5):711-7.
2006: Frank Birklein
Chapter 35 Complex regional pain syndrome.
Handbook of clinical neurology 2006;81():529-46.
2006: Roman Rolke; Walter Magerl; K Andrews Campbell; C Schalber; S Caspari; Frank Birklein; Rolf-Detlef Treede
Quantitative sensory testing: a comprehensive protocol for clinical trials.
European journal of pain (London, England) 2006;10(1):77-88.
2006: Tanja Schlereth; Frank Birklein; Katrin an Haack; Susanne Schiffmann; Heinz Kilbinger; Charles James Kirkpatrick; Ignaz Wessler
In vivo release of non-neuronal acetylcholine from the human skin as measured by dermal microdialysis: effect of botulinum toxin.
British journal of pharmacology 2006;147(2):183-7.
2005: Tanja Schlereth; Nadine Brosda; Frank Birklein
Somatotopic arrangement of sudomotor axon reflex sweating in humans.
Autonomic neuroscience : basic & clinical 2005;123(1-2):76-81.
2005: Daniel Hermann; Tanja Schlereth; Thomas Vogt; Frank Birklein
Clonidine induces nitric oxide- and prostaglandin-mediated vasodilation in healthy human skin.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(6):2266-70.
2005: Frank Birklein; Roman Rolke; Wibke Müller-Forell
Isolated insular infarction eliminates contralateral cold, cold pain, and pinprick perception.
Neurology 2005;65(9):1381.
2005: Frank Birklein; Michael Rowbotham
Does pain change the brain?
Neurology 2005;65(5):666-7.
2005: Heidrun H Krämer; K Schmidt; Stefan Leis; Martin Schmelz; Claudia Sommer; Frank Birklein
Inhibition of neutral endopeptidase (NEP) facilitates neurogenic inflammation.
Experimental neurology 2005;195(1):179-84.
2005: Christian Maihöfner; Hermann O Handwerker; Bernhard Neundörfer; Frank Birklein
Mechanical hyperalgesia in complex regional pain syndrome: a role for TNF-alpha?
Neurology 2005;65(2):311-3.
2005: Tanja Schlereth; Nadine Brosda; Frank Birklein
Spreading of sudomotor axon reflexes in human skin.
Neurology 2005;64(8):1417-21.
2005: Mathias Schreckenberger; Thomas Siessmeier; A Viertmann; Christian Landvogt; Hans-Georg Buchholz; Roman Rolke; Rolf-Detlef Treede; Peter Bartenstein; Frank Birklein
The unpleasantness of tonic pain is encoded by the insular cortex.
Neurology 2005;64(7):1175-83.
2005: Christian Maihöfner; Clemens Forster; Frank Birklein; Bernhard Neundörfer; Hermann O Handwerker
Brain processing during mechanical hyperalgesia in complex regional pain syndrome: a functional MRI study.
Pain 2005;114(1-2):93-103.
2005: Heidrun H Krämer; Roman Rolke; M Hecht; Andreas Bickel; Frank Birklein
Follow-up of advanced diabetic neuropathy: useful variables and possible pitfalls.
Journal of neurology 2005;252(3):315-20.
2005: Tanja Schlereth; Irini Mouka; Gabi Eisenbarth; Martin Winterholler; Frank Birklein
Botulinum toxin A (Botox) and sweating-dose efficacy and comparison to other BoNT preparations.
Autonomic neuroscience : basic & clinical 2005;117(2):120-6.
2005: Frank Birklein
Complex regional pain syndrome.
Journal of neurology 2005;252(2):131-8.
2005: Jürgen J Marx; Frank Thömke; Frank Birklein
[Horner's syndrome -- update on neuroanatomy, topographic diagnosis and etiology].
Fortschritte der Neurologie-Psychiatrie 2005;73(1):23-9.
2004: Heidrun H Krämer; Roman Rolke; Andreas Bickel; Frank Birklein
Thermal thresholds predict painfulness of diabetic neuropathies.
Diabetes care 2004;27(10):2386-91.
2004: Christian Maihöfner; Hermann O Handwerker; Bernhard Neundörfer; Frank Birklein
Cortical reorganization during recovery from complex regional pain syndrome.
Neurology 2004;63(4):693-701.
2004: B Martin Eicke; Kai Milke; Tanja Schlereth; Frank Birklein
Comparison of continuous wave Doppler ultrasound of the radial artery and laser Doppler flowmetry of the fingertips with sympathetic stimulation.
Journal of neurology 2004;251(8):958-62.
2004: Barbara Namer; Andreas Bickel; Heidrun H Krämer; Frank Birklein; Martin Schmelz
Chemically and electrically induced sweating and flare reaction.
Autonomic neuroscience : basic & clinical 2004;114(1-2):72-82.
2004: Stefan Leis; Sonja Drenkhahn; Christoph H Schick; Carsten Arnolt; Martin Schmelz; Frank Birklein; Andreas Bickel
Catecholamine release in human skin--a microdialysis study.
Experimental neurology 2004;188(1):86-93.
2004: Kathrin Hühne; Stefan Leis; Martin Schmelz; Bernd Rautenstrauss; Frank Birklein
A polymorphic locus in the intron 16 of the human angiotensin-converting enzyme (ACE) gene is not correlated with complex regional pain syndrome I (CRPS I).
European journal of pain (London, England) 2004;8(3):221-5.
2004: Stefan Leis; Margarete Weber; Martin Schmelz; Frank Birklein
Facilitated neurogenic inflammation in unaffected limbs of patients with complex regional pain syndrome.
Neuroscience letters 2004;359(3):163-6.
2004: Sebastian Zahn; Stefan Leis; Christoph H Schick; Martin Schmelz; Frank Birklein
No alpha-adrenoreceptor-induced C-fiber activation in healthy human skin.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;96(4):1380-4.
2004: Heidrun H Krämer; Martin Schmelz; Frank Birklein; Andreas Bickel
Electrically stimulated axon reflexes are diminished in diabetic small fiber neuropathies.
Diabetes 2004;53(3):769-74.
2004: Martin J Hecht; Frank Birklein; Martin Winterholler
Successful treatment of axillary hyperhidrosis with very low doses of botulinum toxin B: a pilot study.
Archives of dermatological research 2004;295(8-9):318-9.
2003: Christian Maihöfner; Hermann O Handwerker; Bernhard Neundörfer; Frank Birklein
Patterns of cortical reorganization in complex regional pain syndrome.
Neurology 2003;61(12):1707-15.
2003: Frank Birklein; Gabi Eisenbarth; Frank Erbguth; Martin Winterholler
Botulinum toxin type B blocks sudomotor function effectively: a 6 month follow up.
The Journal of investigative dermatology 2003;121(6):1312-6.
2003: Stefan Leis; Margarete Weber; Andreas Isselmann; Martin Schmelz; Frank Birklein
Substance-P-induced protein extravasation is bilaterally increased in complex regional pain syndrome.
Experimental neurology 2003;183(1):197-204.
2003: M Koban; Stefan Leis; S Schultze-Mosgau; Frank Birklein
Tissue hypoxia in complex regional pain syndrome.
Pain 2003;104(1-2):149-57.
2003: Christoph H Schick; Kerstin S Fronek; A Held; Frank Birklein; Werner Hohenberger; Martin Schmelz
Differential effects of surgical sympathetic block on sudomotor and vasoconstrictor function.
Neurology 2003;60(11):1770-6.
2003: Stefan Schultze-Mosgau; Jörg Wiltfang; Frank Birklein; Friedrich Wilhelm Neukam
Micro-lightguide spectrophotometry as an intraoral monitoring method in free vascular soft tissue flaps.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2003;61(3):292-7; discussion 297.
2003: Heidrun H Krämer; C Angerer; Frank Erbguth; Martin Schmelz; Frank Birklein
Botulinum Toxin A reduces neurogenic flare but has almost no effect on pain and hyperalgesia in human skin.
Journal of neurology 2003;250(2):188-93.
2002: A Bickel; Heidrun H Krämer; Max J Hilz; Frank Birklein; Bernhard Neundörfer; Martin Schmelz
Assessment of the neurogenic flare reaction in small-fiber neuropathies.
Neurology 2002;59(6):917-9.
2002: Annette Kirchner; Hermann Stefan; Martin Schmelz; Karl-Matthias Haslbeck; Frank Birklein
Influence of vagus nerve stimulation on histamine-induced itching.
Neurology 2002;59(1):108-12.
2002: Frank Birklein; Dirk Walther; Hans Bigalke; Martin Winterholler; Frank Erbguth
Sudomotor testing predicts the presence of neutralizing botulinum A toxin antibodies.
Annals of neurology 2002;52(1):68-73.
2002: Margarete Weber; Bernhard Neundörfer; Frank Birklein
[Sudeck's atrophy: pathophysiology and treatment of a complex pain syndrome].
Deutsche medizinische Wochenschrift (1946) 2002;127(8):384-9.
2001: Frank Birklein; Martin Schmelz; S Schifter; Margarete Weber
The important role of neuropeptides in complex regional pain syndrome.
Neurology 2001;57(12):2179-84.
2001: Annette Kirchner; Frank Birklein; Hermann Stefan; Hermann O Handwerker
[Vagus nerve stimulation - a new option for the treatment of chronic pain syndromes?].
Schmerz (Berlin, Germany) 2001;15(4):272-7.
2001: Frank Birklein; W Künzel; N Sieweke
Despite clinical similarities there are significant differences between acute limb trauma and complex regional pain syndrome I (CRPS I).
Pain 2001;93(2):165-71.
2001: Margarete Weber; Frank Birklein; Bernhard Neundörfer; Martin Schmelz
Facilitated neurogenic inflammation in complex regional pain syndrome.
Pain 2001;91(3):251-7.
2001: C Braune; Frank Erbguth; Frank Birklein
Dose thresholds and duration of the local anhidrotic effect of botulinum toxin injections: measured by sudometry.
The British journal of dermatology 2001;144(1):111-7.
2001: B Riedl; T Beckmann; Bernhard Neundörfer; Hermann O Handwerker; Frank Birklein
Autonomic failure after stroke--is it indicative for pathophysiology of complex regional pain syndrome?
Acta neurologica Scandinavica 2001;103(1):27-34.
2000: Frank Birklein; Margarete Weber; Bernhard Neundörfer
Increased skin lactate in complex regional pain syndrome: evidence for tissue hypoxia?
Neurology 2000;55(8):1213-5.
2000: Annette Kirchner; Frank Birklein; Hermann Stefan; Hermann O Handwerker
Left vagus nerve stimulation suppresses experimentally induced pain.
Neurology 2000;55(8):1167-71.
2000: Frank Birklein; Margarete Weber; M Ernst; B Riedl; Bernhard Neundörfer; Hermann O Handwerker
Experimental tissue acidosis leads to increased pain in complex regional pain syndrome (CRPS).
Pain 2000;87(2):227-34.
2000: Frank Birklein; B Riedl; N Sieweke; Margarete Weber; Bernhard Neundörfer
Neurological findings in complex regional pain syndromes--analysis of 145 cases.
Acta neurologica Scandinavica 2000;101(4):262-9.
2000: Frank Birklein; Frank Erbguth
Sudomotor testing discriminates between subjects with and without antibodies against botulinum toxin A--a preliminary observation.
Movement disorders : official journal of the Movement Disorder Society 2000;15(1):146-9.
1999: Frank Birklein; A Spitzer; B Riedl
[The assessment of sudomotor function for diagnosis of autonomic diseases. Principles and methods].
Fortschritte der Neurologie-Psychiatrie 1999;67(7):287-95.
1999: Frank Birklein; B Riedl; Norbert Griessinger; Bernhard Neundörfer
[Complex regional pain syndrome. Clinical and autonomic disorders during acute and chronic illness stages].
Der Nervenarzt 1999;70(4):335-41.
1999: N Sieweke; Frank Birklein; B Riedl; Bernhard Neundörfer; Hermann O Handwerker
Patterns of hyperalgesia in complex regional pain syndrome.
Pain 1999;80(1-2):171-7.
1998: B Riedl; M Nischik; Frank Birklein; Bernhard Neundörfer; Hermann O Handwerker
Spatial extension of sudomotor axon reflex sweating in human skin.
Journal of the autonomic nervous system 1998;69(2-3):83-8.
1998: Frank Birklein; B Riedl; D Claus; Bernhard Neundörfer
Pattern of autonomic dysfunction in time course of complex regional pain syndrome.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society 1998;8(2):79-85.
1998: Frank Birklein; B Riedl; Bernhard Neundörfer; Hermann O Handwerker
Sympathetic vasoconstrictor reflex pattern in patients with complex regional pain syndrome.
Pain 1998;75(1):93-100.
1997: Frank Birklein; D Claus; B Riedl; Bernhard Neundörfer; Hermann O Handwerker
Effects of cutaneous histamine application in patients with sympathetic reflex dystrophy.
Muscle & nerve 1997;20(11):1389-95.
1997: A Spitzer; Eberhard Lang; Frank Birklein; D Claus; Bernhard Neundörfer
Cardiac autonomic involvement and peripheral nerve function in patients with diabetic neuropathy.
Functional neurology 1997;12(3-4):115-22.
1997: Frank Birklein; B Riedl; D Claus; Bernhard Neundörfer; Hermann O Handwerker
Cutaneous norepinephrine application in complex regional pain syndrome.
European journal of pain (London, England) 1997;1(2):123-32.
1997: Frank Birklein; Reinhard Sittl; A Spitzer; D Claus; Bernhard Neundörfer; Hermann O Handwerker
Sudomotor function in sympathetic reflex dystrophy.
Pain 1997;69(1-2):49-54.