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Wayne Carmichael

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2008: Wayne W Carmichael
A world overview--one-hundred-twenty-seven years of research on toxic cyanobacteria--where do we go from here?
Advances in experimental medicine and biology 2008;619():105-25.
2007: Elizabeth D Hilborn; Wayne W Carmichael; Raquel M Soares; Moucun Yuan; Jerome C Servaites; H A Barton; Sandra Maria Feliciano de Oliveira Azevedo
Serologic evaluation of human microcystin exposure.
Environmental toxicology 2007;22(5):459-63.
2006: Moucun Yuan; Wayne W Carmichael; Elizabeth D Hilborn
Microcystin analysis in human sera and liver from human fatalities in Caruaru, Brazil 1996.
Toxicon : official journal of the International Society on Toxinology 2006;48(6):627-40.
2006: Jennifer L Ott; Wayne W Carmichael
LC/ESI/MS method development for the analysis of hepatotoxic cyclic peptide microcystins in animal tissues.
Toxicon : official journal of the International Society on Toxinology 2006;47(7):734-41.
2006: Raquel M Soares; Moucun Yuan; Jerome C Servaites; Alvimar Delgado; Valéria F Magalhães; Elizabeth D Hilborn; Wayne W Carmichael; Sandra Maria Feliciano de Oliveira Azevedo
Sublethal exposure from microcystins to renal insufficiency patients in Rio de Janeiro, Brazil.
Environmental toxicology 2006;21(2):95-103.
2006: Wayne W Carmichael; RenHui Li
Cyanobacteria toxins in the Salton Sea.
Saline systems 2006;2():5.
2005: Elizabeth D Hilborn; Wayne W Carmichael; Moucun Yuan; Sandra Maria Feliciano de Oliveira Azevedo
A simple colorimetric method to detect biological evidence of human exposure to microcystins.
Toxicon : official journal of the International Society on Toxinology 2005;46(2):218-21.
2004: Moucun Yuan; Wayne W Carmichael
Detection and analysis of the cyanobacterial peptide hepatotoxins microcystin and nodularin using SELDI-TOF mass spectrometry.
Toxicon : official journal of the International Society on Toxinology 2004;44(5):561-70.
2003: Zakaria A Mohamed; Wayne W Carmichael; Ahmed A Hussein
Estimation of microcystins in the freshwater fish Oreochromis niloticus in an Egyptian fish farm containing a Microcystis bloom.
Environmental toxicology 2003;18(2):137-41.
2002: Sandra Maria Feliciano de Oliveira Azevedo; Wayne W Carmichael; Elise M Jochimsen; Kenneth L Rinehart; Sharon Lau; Glen R Shaw; Geoff Eaglesham
Human intoxication by microcystins during renal dialysis treatment in Caruaru-Brazil.
Toxicology 2002;181-182():441-6.
2002: Jesper Laub; Peter Henriksen; Scott M Brittain; Jim Wang; Wayne W Carmichael; Kenneth L Rinehart; Ojvind Moestrup
[ADMAdda5]-microcystins in Planktothrix agardhii strain PH-123 (cyanobacteria)--importance for monitoring of microcystins in the environment.
Environmental toxicology 2002;17(4):351-7.
2001: Wayne W Carmichael; Sandra Maria Feliciano de Oliveira Azevedo; J S An; R J Molica; Elise M Jochimsen; S Lau; Kenneth L Rinehart; Glen R Shaw; Geoff Eaglesham
Human fatalities from cyanobacteria: chemical and biological evidence for cyanotoxins.
Environmental health perspectives 2001;109(7):663-8.
2001: R Li; Wayne W Carmichael; Scott M Brittain; Geoff Eaglesham; Glen R Shaw; Aparat Mahakhant; N Noparatnaraporn; Wichien Yongmanitchai; K Kaya; M M Watanabe
Isolation and identification of the cyanotoxin cylindrospermopsin and deoxy-cylindrospermopsin from a Thailand strain of Cylindrospermopsis raciborskii (Cyanobacteria).
Toxicon : official journal of the International Society on Toxinology 2001;39(7):973-80.
2001: H Park; Michio Namikoshi; Scott M Brittain; Wayne W Carmichael; T Murphy
[D-Leu(1)] microcystin-LR, a new microcystin isoplated from waterbloom in a Canadian prairie lake.
Toxicon : official journal of the International Society on Toxinology 2001;39(6):855-62.
2000: Scott M Brittain; Zakaria A Mohamed; J Wang; V K Lehmann; Wayne W Carmichael; Kenneth L Rinehart
Isolation and characterization of microcystins from a river nile strain of Oscillatoria tenuis Agardh ex Gomont.
Toxicon : official journal of the International Society on Toxinology 2000;38(12):1759-71.
1999: Wayne W Carmichael; J An
Using an enzyme linked immunosorbent assay (ELISA) and a protein phosphatase inhibition assay (PPIA) for the detection of microcystins and nodularins.
Natural toxins 1999;7(6):377-85.
1998: Elise M Jochimsen; Wayne W Carmichael; J S An; Denise M Cardo; ST Cookson; C E Holmes; M B Antunes; D A de Melo Filho; T M Lyra; V S Barreto; Sandra Maria Feliciano de Oliveira Azevedo; William R Jarvis
Liver failure and death after exposure to microcystins at a hemodialysis center in Brazil.
The New England journal of medicine 1998;338(13):873-8.
1998: Michio Namikoshi; Moucun Yuan; Kaarina Sivonen; Wayne W Carmichael; Kenneth L Rinehart; Leo Rouhiainen; F Sun; Scott M Brittain; A Otsuki
Seven new microcystins possessing two L-glutamic acid units, isolated from Anabaena sp. strain 186.
Chemical research in toxicology 1998;11(2):143-9.
1997: L Shi; Wayne W Carmichael
pp1-cyano2, a protein serine/threonine phosphatase 1 gene from the cyanobacterium Microcystis aeruginosa UTEX 2063.
Archives of microbiology 1997;168(6):528-31.
1997: Wayne W Carmichael; W R Evans; Q Q Yin; P Bell; E Moczydlowski
Evidence for paralytic shellfish poisons in the freshwater cyanobacterium Lyngbya wollei (Farlow ex Gomont) comb. nov.
Applied and environmental microbiology 1997;63(8):3104-10.
1997: Peter Henriksen; Wayne W Carmichael; J An; Ojvind Moestrup
Detection of an anatoxin-a(s)-like anticholinesterase in natural blooms and cultures of cyanobacteria/blue-green algae from Danish lakes and in the stomach contents of poisoned birds.
Toxicon : official journal of the International Society on Toxinology 1997;35(6):901-13.
1995: L Shi; Wayne W Carmichael; I Miller
Immuno-gold localization of hepatotoxins in cyanobacterial cells.
Archives of microbiology 1995;163(1):7-15.
1994: J An; Wayne W Carmichael
Use of a colorimetric protein phosphatase inhibition assay and enzyme linked immunosorbent assay for the study of microcystins and nodularins.
Toxicon : official journal of the International Society on Toxinology 1994;32(12):1495-507.
1994: Wayne W Carmichael
The toxins of cyanobacteria.
Scientific American 1994;270(1):78-86.
1993: R R Stotts; Michio Namikoshi; Wanda M Haschek; Kenneth L Rinehart; Wayne W Carmichael; A M Dahlem; Val R Beasley
Structural modifications imparting reduced toxicity in microcystins from Microcystis spp.
Toxicon : official journal of the International Society on Toxinology 1993;31(6):783-9.
1993: Michio Namikoshi; B W Choi; F Sun; Kenneth L Rinehart; W R Evans; Wayne W Carmichael
Chemical characterization and toxicity of dihydro derivatives of nodularin and microcystin-LR, potent cyanobacterial cyclic peptide hepatotoxins.
Chemical research in toxicology 1993;6(2):151-8.
1992: Kaarina Sivonen; Michio Namikoshi; W R Evans; B V Gromov; Wayne W Carmichael; Kenneth L Rinehart
Isolation and structures of five microcystins from a Russian Microcystis aeruginosa strain CALU 972.
Toxicon : official journal of the International Society on Toxinology 1992;30(11):1481-5.
1992: Michio Namikoshi; Kaarina Sivonen; W R Evans; F Sun; Wayne W Carmichael; Kenneth L Rinehart
Isolation and structures of microcystins from a cyanobacterial water bloom (Finland).
Toxicon : official journal of the International Society on Toxinology 1992;30(11):1473-9.
1992: Kaarina Sivonen; O M Skulberg; Michio Namikoshi; W R Evans; Wayne W Carmichael; Kenneth L Rinehart
Two methyl ester derivatives of microcystins, cyclic heptapeptide hepatotoxins, isolated from Anabaena flos-aquae strain CYA 83/1.
Toxicon : official journal of the International Society on Toxinology 1992;30(11):1465-71.
1992: Michio Namikoshi; Kaarina Sivonen; W R Evans; Wayne W Carmichael; F Sun; Leo Rouhiainen; R Luukkainen; Kenneth L Rinehart
Two new L-serine variants of microcystins-LR and -RR from Anabaena sp. strains 202 A1 and 202 A2.
Toxicon : official journal of the International Society on Toxinology 1992;30(11):1457-64.
1992: Michio Namikoshi; Kaarina Sivonen; W R Evans; Wayne W Carmichael; Leo Rouhiainen; R Luukkainen; Kenneth L Rinehart
Structures of three new homotyrosine-containing microcystins and a new homophenylalanine variant from Anabaena sp. strain 66.
Chemical research in toxicology 1992;5(5):661-6.
1992: J Kiviranta; Michio Namikoshi; Kaarina Sivonen; W R Evans; Wayne W Carmichael; Kenneth L Rinehart
Structure determination and toxicity of a new microcystin from Microcystis aeruginosa strain 205.
Toxicon : official journal of the International Society on Toxinology 1992;30(9):1093-8.
1992: Kaarina Sivonen; Michio Namikoshi; W R Evans; Wayne W Carmichael; F Sun; Leo Rouhiainen; R Luukkainen; Kenneth L Rinehart
Isolation and characterization of a variety of microcystins from seven strains of the cyanobacterial genus Anabaena.
Applied and environmental microbiology 1992;58(8):2495-500.
1992: Kaarina Sivonen; Michio Namikoshi; W R Evans; M Färdig; Wayne W Carmichael; Kenneth L Rinehart
Three new microcystins, cyclic heptapeptide hepatotoxins, from Nostoc sp. strain 152.
Chemical research in toxicology 1992;5(4):464-9.
1992: R Nishiwaki-Matsushima; Toshihisa Ohta; S Nishiwaki; Masami Suganuma; K Kohyama; T Ishikawa; Wayne W Carmichael; Hirota Fujiki
Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR.
Journal of cancer research and clinical oncology 1992;118(6):420-4.
1991: Ken-Ichi Harada; K Ogawa; Y Kimura; H Murata; M Suzuki; P M Thorn; W R Evans; Wayne W Carmichael
Microcystins from Anabaena flos-aquae NRC 525-17.
Chemical research in toxicology 1991;4(5):535-40.
1991: S B Hooser; Val R Beasley; L L Waite; M S Kuhlenschmidt; Wayne W Carmichael; Wanda M Haschek
Actin filament alterations in rat hepatocytes induced in vivo and in vitro by microcystin-LR, a hepatotoxin from the blue-green alga, Microcystis aeruginosa.
Veterinary pathology 1991;28(4):259-66.
1991: S B Hooser; M S Kuhlenschmidt; A M Dahlem; Val R Beasley; Wayne W Carmichael; Wanda M Haschek
Uptake and subcellular localization of tritiated dihydro-microcystin-LR in rat liver.
Toxicon : official journal of the International Society on Toxinology 1991;29(6):589-601.
1991: E G Hyde; Wayne W Carmichael
Anatoxin-a(s), a naturally occurring organophosphate, is an irreversible active site-directed inhibitor of acetylcholinesterase (EC 3.1.1.7).
Journal of biochemical toxicology 1991;6(3):195-201.
1990: R Matsushima; S Yoshizawa; Masahiko Watanabe; K Harada; M Furusawa; Wayne W Carmichael; Hirota Fujiki
In vitro and in vivo effects of protein phosphatase inhibitors, microcystins and nodularin, on mouse skin and fibroblasts.
Biochemical and biophysical research communications 1990;171(2):867-74.
1990: Kaarina Sivonen; Wayne W Carmichael; Michio Namikoshi; Kenneth L Rinehart; A M Dahlem; S I Niemelä
Isolation and characterization of hepatotoxic microcystin homologs from the filamentous freshwater cyanobacterium Nostoc sp. strain 152.
Applied and environmental microbiology 1990;56(9):2650-7.
1990: W O Cook; G A Iwamoto; David J Schaeffer; Wayne W Carmichael; Val R Beasley
Pathophysiologic effects of anatoxin-a(s) in anaesthetized rats: the influence of atropine and artificial respiration.
Pharmacology & toxicology 1990;67(2):151-5.
1990: Jussi Meriluoto; John E Eriksson; K Harada; A M Dahlem; Kaarina Sivonen; Wayne W Carmichael
Internal surface reversed-phase high-performance liquid chromatographic separation of the cyanobacterial peptide toxins microcystin-LA, -LR, -YR, -RR and nodularin.
Journal of chromatography 1990;509(2):390-5.
1990: S Yoshizawa; R Matsushima; Masahiko Watanabe; K Harada; A Ichihara; Wayne W Carmichael; Hirota Fujiki
Inhibition of protein phosphatases by microcystins and nodularin associated with hepatotoxicity.
Journal of cancer research and clinical oncology 1990;116(6):609-14.
1990: Ken-Ichi Harada; K Matsuura; M Suzuki; M F Watanabe; S Oishi; A M Dahlem; Val R Beasley; Wayne W Carmichael
Isolation and characterization of the minor components associated with microcystins LR and RR in the cyanobacterium (blue-green algae).
Toxicon : official journal of the International Society on Toxinology 1990;28(1):55-64.
1990: S B Hooser; Val R Beasley; E J Basgall; Wayne W Carmichael; Wanda M Haschek
Microcystin-LR-induced ultrastructural changes in rats.
Veterinary pathology 1990;27(1):9-15.
1989: W O Cook; J A Dellinger; S S Singh; A M Dahlem; Wayne W Carmichael; Val R Beasley
Regional brain cholinesterase activity in rats injected intraperitoneally with anatoxin-a(s) or paraoxon.
Toxicology letters 1989;49(1):29-34.
1989: Val R Beasley; A M Dahlem; W O Cook; W M Valentine; R A Lovell; S B Hooser; K Harada; M Suzuki; Wayne W Carmichael
Diagnostic and clinically important aspects of cyanobacterial (blue-green algae) toxicoses.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 1989;1(4):359-65.
1989: Kaarina Sivonen; K Kononen; Wayne W Carmichael; A M Dahlem; Kenneth L Rinehart; J Kiviranta; S I Niemela
Occurrence of the hepatotoxic cyanobacterium Nodularia spumigena in the Baltic Sea and structure of the toxin.
Applied and environmental microbiology 1989;55(8):1990-5.
1989: R A Lovell; D J Schaeffer; S B Hooser; Wanda M Haschek; A M Dahlem; Wayne W Carmichael; Val R Beasley
Toxicity of intraperitoneal doses of microcystin-LR in two strains of male mice.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 1989;9(3):221-37.
1989: S B Hooser; Val R Beasley; R A Lovell; Wayne W Carmichael; Wanda M Haschek
Toxicity of microcystin LR, a cyclic heptapeptide hepatotoxin from Microcystis aeruginosa, to rats and mice.
Veterinary pathology 1989;26(3):246-52.
1989: A M Dahlem; A S Hassan; S P Swanson; Wayne W Carmichael; Val R Beasley
A model system for studying the bioavailability of intestinally administered microcystin-LR, a hepatotoxic peptide from the cyanobacterium Microcystis aeruginosa.
Pharmacology & toxicology 1989;64(2):177-81.
1989: T Krishnamurthy; L Szafraniec; D F Hunt; J Shabanowitz; J R Yates; C R Hauer; Wayne W Carmichael; O Skulberg; G A Codd; S Missler
Structural characterization of toxic cyclic peptides from blue-green algae by tandem mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(3):770-4.
1989: Ken-Ichi Harada; Y Kimura; K Ogawa; M Suzuki; A M Dahlem; Val R Beasley; Wayne W Carmichael
A new procedure for the analysis and purification of naturally occurring anatoxin-a from the blue-green alga Anabaena flos-aquae.
Toxicon : official journal of the International Society on Toxinology 1989;27(12):1289-96.
1988: Ken-Ichi Harada; K Matsuura; M Suzuki; H Oka; M F Watanabe; S Oishi; A M Dahlem; Val R Beasley; Wayne W Carmichael
Analysis and purification of toxic peptides from cyanobacteria by reversed-phase high-performance liquid chromatography.
Journal of chromatography 1988;448(2):275-83.
1988: Wayne W Carmichael; J T Eschedor; G M Patterson; R E Moore
Toxicity and partial structure of a hepatotoxic peptide produced by the cyanobacterium Nodularia spumigena Mertens emend. L575 from New Zealand.
Applied and environmental microbiology 1988;54(9):2257-63.
1988: N A Mahmood; Wayne W Carmichael; D Pfahler
Anticholinesterase poisonings in dogs from a cyanobacterial (blue-green algae) bloom dominated by Anabaena flos-aquae.
American journal of veterinary research 1988;49(4):500-3.
1988: W O Cook; Val R Beasley; A M Dahlem; J A Dellinger; K S Harlin; Wayne W Carmichael
Comparison of effects of anatoxin-a(s) and paraoxon, physostigmine and pyridostigmine on mouse brain cholinesterase activity.
Toxicon : official journal of the International Society on Toxinology 1988;26(8):750-3.
1988: Wayne W Carmichael; V Beasley; D L Bunner; Jacobus Eloff; I Falconer; P Gorham; K Harada; T Krishnamurthy; M J Yu; R E Moore
Naming of cyclic heptapeptide toxins of cyanobacteria (blue-green algae).
Toxicon : official journal of the International Society on Toxinology 1988;26(11):971-3.
1988: Wayne W Carmichael; J W He; J Eschedor; Z R He; Y M Juan
Partial structural determination of hepatotoxic peptides from Microcystis aeruginosa (cyanobacterium) collected in ponds of central China.
Toxicon : official journal of the International Society on Toxinology 1988;26(12):1213-7.
1988: K Berg; J Wyman; Wayne W Carmichael; A Dabholkar
Isolated rat liver perfusion studies with cyclic heptapeptide toxins of Microcystis and Oscillatoria (freshwater cyanobacteria).
Toxicon : official journal of the International Society on Toxinology 1988;26(9):827-37.
1988: Ken-Ichi Harada; M Suzuki; A M Dahlem; Val R Beasley; Wayne W Carmichael; Kenneth L Rinehart
Improved method for purification of toxic peptides produced by cyanobacteria.
Toxicon : official journal of the International Society on Toxinology 1988;26(5):433-9.
1988: W C Theiss; Wayne W Carmichael; J Wyman; R Bruner
Blood pressure and hepatocellular effects of the cyclic heptapeptide toxin produced by the freshwater cyanobacterium (blue-green alga) Microcystis aeruginosa strain PCC-7820.
Toxicon : official journal of the International Society on Toxinology 1988;26(7):603-13.
1987: F D Galey; Val R Beasley; Wayne W Carmichael; G Kleppe; S B Hooser; Wanda M Haschek
Blue-green algae (Microcystis aeruginosa) hepatotoxicosis in dairy cows.
American journal of veterinary research 1987;48(9):1415-20.
1987: N A Mahmood; Wayne W Carmichael
Anatoxin-a(s), an anticholinesterase from the cyanobacterium Anabaena flos-aquae NRC-525-17.
Toxicon : official journal of the International Society on Toxinology 1987;25(11):1221-7.
1986: T Krishnamurthy; Wayne W Carmichael; E W Sarver
Toxic peptides from freshwater cyanobacteria (blue-green algae). I. Isolation, purification and characterization of peptides from Microcystis aeruginosa and Anabaena flos-aquae.
Toxicon : official journal of the International Society on Toxinology 1986;24(9):865-73.
1986: N A Mahmood; Wayne W Carmichael
The pharmacology of anatoxin-a(s), a neurotoxin produced by the freshwater cyanobacterium Anabaena flos-aquae NRC 525-17.
Toxicon : official journal of the International Society on Toxinology 1986;24(5):425-34.
1986: N A Mahmood; Wayne W Carmichael
Paralytic shellfish poisons produced by the freshwater cyanobacterium Aphanizomenon flos-aquae NH-5.
Toxicon : official journal of the International Society on Toxinology 1986;24(2):175-86.