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Jérôme Bouchet

Research Profile

Chemicals & Drugs

Living Beings

HIV-1
Mouse

Anatomy

Phenomena

Protein Binding

Concepts & Ideas

Procedures

Two-Hybrid System Techniques

Physiology

Endocytosis

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Publications

TOP 3
Julie Matz; Oscar Henrique Pereira Ramos; Olivier Combes; Pascal Kessler; Loïc Martin; Francis Barin; Daniel Baty; Serge Benichou; Jérôme Bouchet; Patrick Chames
Straightforward selection of broadly neutralizing single-domain antibodies targeting the conserved CD4 and coreceptor binding sites of HIV-1 gp120.
Jérôme Bouchet; Patrick Chames; Carolin A Guenzel; Cécile Hérate; Annika Järviluoma; Isabelle Maridonneau-Parini; Julie Mazzolini; Florence Niedergang; Salomeh Rafie; Kalle Saksela; Christel Vérollet; Daniel Baty; Serge Benichou
Single-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functions.
Annika Järviluoma; Sebastian Lülf; Anna R Mäkelä; Serge Benichou; Jérôme Bouchet; Matthias Geyer; Tomas Strandin; Kalle Saksela
High-affinity target binding engineered via fusion of a single-domain antibody fragment with a ligand-tailored SH3 domain.

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All Publications

2013: Julie Matz; Oscar Henrique Pereira Ramos; Olivier Combes; Pascal Kessler; Loïc Martin; Francis Barin; Daniel Baty; Serge Benichou; Jérôme Bouchet; Patrick Chames
Straightforward selection of broadly neutralizing single-domain antibodies targeting the conserved CD4 and coreceptor binding sites of HIV-1 gp120.
Journal of virology 2013;87(2):1137-49.
2012: Jérôme Bouchet; Patrick Chames; Carolin A Guenzel; Cécile Hérate; Annika Järviluoma; Isabelle Maridonneau-Parini; Julie Mazzolini; Florence Niedergang; Salomeh Rafie; Kalle Saksela; Christel Vérollet; Daniel Baty; Serge Benichou
Single-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functions.
Journal of virology 2012;86(9):4856-67.
2012: Annika Järviluoma; Sebastian Lülf; Anna R Mäkelä; Serge Benichou; Jérôme Bouchet; Matthias Geyer; Tomas Strandin; Kalle Saksela
High-affinity target binding engineered via fusion of a single-domain antibody fragment with a ligand-tailored SH3 domain.
PloS one 2012;7(7):e40331.
2011: Jérôme Bouchet; Stéphane E Basmaciogullari; Pavel Chrobak; Bettina Stolp; Nathalie Bouchard; Oliver T Fackler; Patrick Chames; Paul Jolicoeur; Serge Benichou; Daniel Baty
Inhibition of the Nef regulatory protein of HIV-1 by a single-domain antibody.
Blood 2011;117(13):3559-68.
2010: Christel Vérollet; Yan Mei Zhang; Véronique Le Cabec; Julie Mazzolini; Guillaume Charrière; Arnaud Labrousse; Jérôme Bouchet; Indira Medina; Erik Biessen; Florence Niedergang; Serge Bénichou; Isabelle Maridonneau-Parini
HIV-1 Nef triggers macrophage fusion in a p61Hck- and protease-dependent manner.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(12):7030-9.
2010: Julie Mazzolini; Floriane Herit; Jérôme Bouchet; Alexandre Benmerah; Serge Benichou; Florence Niedergang
Inhibition of phagocytosis in HIV-1-infected macrophages relies on Nef-dependent alteration of focal delivery of recycling compartments.
Blood 2010;115(21):4226-36.
2009: Nadine Laguette; Christelle Brégnard; Jérôme Bouchet; Alexandre Benmerah; Serge Benichou; Stéphane Basmaciogullari
Nef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase.
Journal of virology 2009;83(14):7117-28.
2009: Benedicte F Py; Stéphane Basmaciogullari; Jérôme Bouchet; Marion Zarka; Ivan C Moura; Marc Benhamou; Renato C Monteiro; Hakim Hocini; Ricardo Madrid; Serge Benichou
The phospholipid scramblases 1 and 4 are cellular receptors for the secretory leukocyte protease inhibitor and interact with CD4 at the plasma membrane.
PloS one 2009;4(3):e5006.
2008: Sebastian Hannemann; Ricardo Madrid; Jana Stastna; Thomas Kitzing; Judith E Gasteier; André Schönichen; Jérôme Bouchet; Alberto Jimenez; Matthias Geyer; Robert Grosse; Serge Benichou; Oliver T Fackler
The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing.
The Journal of biological chemistry 2008;283(41):27891-903.
2007: Benedicte F Py; Jérôme Bouchet; Guillaume Jacquot; Nathalie Sol-Foulon; Stéphane Basmaciogullari; Olivier Schwartz; Martine Biard-Piechaczyk; Serge Benichou
The Siva protein is a novel intracellular ligand of the CD4 receptor that promotes HIV-1 envelope-induced apoptosis in T-lymphoid cells.
Apoptosis : an international journal on programmed cell death 2007;12(10):1879-92.
2007: Guillaume Jacquot; Erwann Le Rouzic; Annie David; Julie Mazzolini; Jérôme Bouchet; Serge Bouaziz; Florence Niedergang; Gianfranco Pancino; Serge Benichou
Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages.
Retrovirology 2007;4():84.
2007: Anne Burtey; Joshua Z Rappoport; Jérôme Bouchet; Stéphane Basmaciogullari; John C Guatelli; Sanford M Simon; Serge Benichou; Alexandre Benmerah
Dynamic interaction of HIV-1 Nef with the clathrin-mediated endocytic pathway at the plasma membrane.
Traffic (Copenhagen, Denmark) 2007;8(1):61-76.
2006: Scott H Coleman; Ricardo Madrid; Nanette Van Damme; Richard S Mitchell; Jérôme Bouchet; Cecile Servant; Satish Pillai; Serge Benichou; John C Guatelli
Modulation of cellular protein trafficking by human immunodeficiency virus type 1 Nef: role of the acidic residue in the ExxxLL motif.
Journal of virology 2006;80(4):1837-49.
2005: Guillaume Montagnac; Anahi Mollà-Herman; Jérôme Bouchet; Linda C H Yu; Daniel H Conrad; Mary H Perdue; Alexandre Benmerah
Intracellular trafficking of CD23: differential regulation in humans and mice by both extracellular and intracellular exons.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5562-72.
2005: Ricardo Madrid; Katy Janvier; Douglas Hitchin; John Day; Scott Coleman; Colleen M Noviello; Jérôme Bouchet; Alexandre Benmerah; John C Guatelli; Serge Benichou
Nef-induced alteration of the early/recycling endosomal compartment correlates with enhancement of HIV-1 infectivity.
The Journal of biological chemistry 2005;280(6):5032-44.
2005: Ricardo Madrid; Judith E Gasteier; Jérôme Bouchet; Sebastian Schröder; Matthias Geyer; Serge Benichou; Oliver T Fackler
Oligomerization of the diaphanous-related formin FHOD1 requires a coiled-coil motif critical for its cytoskeletal and transcriptional activities.
FEBS letters 2005;579(2):441-8.