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William Kim

Research Profile

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Publications

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Raj Kurpad; Matthew Nielsen; Ava Pettiford; Wendy Rathmell; Heather Schultz; LuAnn Smith; Eric Wallen; Young E Whang; Julia Fielding; Paul Godley; William Kim; Raj S Pruthi
A multidisciplinary approach to the management of urologic malignancies: does it influence diagnostic and treatment decisions?
Raj S Pruthi; Matthew Nielsen; Samuel Heathcote; Eric Wallen; W Kim Rathmell; Paul Godley; Young Whang; Julia Fielding; Heather Schultz; Gayle Grigson; Angela Smith; William Kim
A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: clinical and pathological results.
C Lance Cowey; Chirag Amin; Raj S Pruthi; Eric Wallen; Matthew Nielsen; Gayle Grigson; Cathy Watkins; Keith V Nance; Jeffrey Crane; Mark Jalkut; Dominic T Moore; William Kim; Paul A Godley; Young E Whang; Julia R Fielding; Wendy Rathmell
Neoadjuvant clinical trial with sorafenib for patients with stage II or higher renal cell carcinoma.

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All Publications

2011: Raj Kurpad; Matthew Nielsen; Ava Pettiford; Wendy Rathmell; Heather Schultz; LuAnn Smith; Eric Wallen; Young E Whang; Julia Fielding; Paul Godley; William Kim; Raj S Pruthi
A multidisciplinary approach to the management of urologic malignancies: does it influence diagnostic and treatment decisions?
Urologic oncology 2011;29(4):378-82.
2010: Raj S Pruthi; Matthew Nielsen; Samuel Heathcote; Eric Wallen; W Kim Rathmell; Paul Godley; Young Whang; Julia Fielding; Heather Schultz; Gayle Grigson; Angela Smith; William Kim
A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: clinical and pathological results.
BJU international 2010;106(3):349-54.
2010: C Lance Cowey; Chirag Amin; Raj S Pruthi; Eric Wallen; Matthew Nielsen; Gayle Grigson; Cathy Watkins; Keith V Nance; Jeffrey Crane; Mark Jalkut; Dominic T Moore; William Kim; Paul A Godley; Young E Whang; Julia R Fielding; Wendy Rathmell
Neoadjuvant clinical trial with sorafenib for patients with stage II or higher renal cell carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(9):1502-7.
2009: William Kim; Mircea Ivan
Molecular responses to hypoxia: ancient pathways, clinical promises.
Journal of cellular and molecular medicine 2009;13(9A):2757-8.
2009: William Kim; Samanthi Perera; Bing Zhou; Julian Carretero; Jen Jen Yeh; Samuel A Heathcote; Autumn L Jackson; Petros Nikolinakos; Beatriz Ospina; George Naumov; Kathleyn A Brandstetter; Victor J Weigman; Sara Zaghlul; David Hayes; Robert F Padera; John V Heymach; Andrew L Kung; Norman E Sharpless; William G Kaelin; Kwok-Kin Wong
HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice.
The Journal of clinical investigation 2009;119(8):2160-70.
2009: Yi Wang; olga roche; Mathew S Yan; Greg Finak; Andrew J Evans; Julie L Metcalf; Bridgid E Hast; Sara C Hanna; Bill Wondergem; Kyle A Furge; Meredith S. Irwin; William Kim; Bin Tean Teh; Sergio Grinstein; Morag Park; Philip A Marsden; Michael Ohh
Regulation of endocytosis via the oxygen-sensing pathway.
Nature medicine 2009;15(3):319-24.
2008: William Kim; Norman E Sharpless
VHL inactivation: a new road to senescence.
Cancer cell 2008;13(4):295-7.
2008: Sara C Hanna; Samuel A Heathcote; William Kim
mTOR pathway in renal cell carcinoma.
Expert review of anticancer therapy 2008;8(2):283-92.
2007: Kimberly B Petermann; Gabriela I Rozenberg; Daniel Zedek; Pamela A Groben; Karen P McKinnon; Christin Buehler; William Kim; Janiel M Shields; Shannon Penland; James E Bear; Nancy E Thomas; Jonathan S Serody; Norman E Sharpless
CD200 is induced by ERK and is a potential therapeutic target in melanoma.
The Journal of clinical investigation 2007;117(12):3922-9.
2007: Mindy A Maynard; Andrew J Evans; Wei Shi; William Kim; Fei-Fei Liu; Michael Ohh
Dominant-negative HIF-3 alpha 4 suppresses VHL-null renal cell carcinoma progression.
Cell cycle (Georgetown, Tex.) 2007;6(22):2810-6.
2007: Haifeng Yang; Yoji Andrew MINAMISHIMA; Qin Yan; Suzanne Schlisio; Benjamin L Ebert; Xiaoping Zhang; Liang Zhang; William Kim; Aria F Olumi; William G Kaelin
pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2.
Molecular cell 2007;28(1):15-27.
2007: William Irvin; Gigi MacDonald; J Smith; William Kim
Dexamethasone-induced posterior reversible encephalopathy syndrome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(17):2484-6.
2007: Andrew J Evans; Ryan C Russell; olga roche; T Nadine Burry; Jason E Fish; Vinca W K Chow; William Kim; Arthy Saravanan; Mindy A Maynard; Michelle L Gervais; Roxana I Sufan; Andrew M Roberts; Leigh A Wilson; Mark Betten; Cindy Vandewalle; Geert Berx; Philip A Marsden; Meredith S. Irwin; Bin Tean Teh; Michael A S Jewett; Michael Ohh
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail.
Molecular and cellular biology 2007;27(1):157-69.
2006: William Kim; Norman E Sharpless
The regulation of INK4/ARF in cancer and aging.
Cell 2006;127(2):265-75.
2006: William Kim; Michal Safran; Marshall R M Buckley; Benjamin L Ebert; Jonathan Glickman; Marcus W Bosenberg; Meredith M Regan; William G Kaelin
Failure to prolyl hydroxylate hypoxia-inducible factor alpha phenocopies VHL inactivation in vivo.
The EMBO journal 2006;25(19):4650-62.
2006: William Kim; William G Kaelin
Molecular pathways in renal cell carcinoma--rationale for targeted treatment.
Seminars in oncology 2006;33(5):588-95.
2006: Hongbin Ji; Danan Li; Liang Chen; Takeshi Shimamura; Susumu Kobayashi; Kate McNamara; Umar Mahmood; Albert Mitchell; Yangping Sun; Ruqayyah Al-Hashem; Lucian R Chirieac; Robert F Padera; Roderick T Bronson; William Kim; Pasi A Janne; Geoffrey I Shapiro; Daniel Tenen; Bruce E Johnson; Ralph Weissleder; Norman E Sharpless; Kwok-Kin Wong
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies.
Cancer cell 2006;9(6):485-95.
2006: Michal Safran; William Kim; Fionnuala O'Connell; Lee Flippin; Volkmar Günzler; James W Horner; Ronald A DePinho; William G Kaelin
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(1):105-10.
2004: William Kim; William G Kaelin
Role of VHL gene mutation in human cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(24):4991-5004.
2004: Haifeng Yang; Mircea Ivan; Jung-Hyun Min; William Kim; William G Kaelin
Analysis of von Hippel-Lindau hereditary cancer syndrome: implications of oxygen sensing.
Methods in enzymology 2004;381():320-35.
2003: Keiichi Kondo; William Kim; Mirna Lechpammer; William G Kaelin
Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth.
PLoS biology 2003;1(3):E83.
2003: Michal Safran; William Kim; Andrew L Kung; James W Horner; Ronald A DePinho; William G Kaelin
Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination.
Molecular imaging 2003;2(4):297-302.
2003: William Kim; William G Kaelin
The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer.
Current opinion in genetics & development 2003;13(1):55-60.
2002: Michael Ohh; William Kim; Javid Moslehi; Yuzhi Chen; Vincent Chau; Margaret A Read; William G Kaelin
An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells.
EMBO reports 2002;3(2):177-82.
2001: Mircea Ivan; Keiichi Kondo; Haifeng Yang; William Kim; J Valiando; Michael Ohh; A Salic; J M Asara; William Stratton Lane; William G Kaelin
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.
Science (New York, N.Y.) 2001;292(5516):464-8.
1995: D A Twillie; Mario A Eisenberger; Michael A Carducci; W S Hseih; William Kim; Jonathan W Simons
Interleukin-6: a candidate mediator of human prostate cancer morbidity.
Urology 1995;45(3):542-9.