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Jonathan Chernoff

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Sonali Jalan Rawat; Caretha L Creasy; Jeffrey R Peterson; Jonathan Chernoff
The tumor suppressor Mst1 promotes changes in the cellular redox state by phosphorylation and inactivation of peroxiredoxin-1 protein.
Rachelle Kosoff; Maria Radu; Hoi Yee Chow; Jonathan Chernoff
Pak2 kinase restrains mast cell FcεRI receptor signaling through modulation of Rho protein guanine nucleotide exchange factor (GEF) activity.
Hoi Yee Chow; Sergio G Duron; J Silvio Gutkind; Klaus P Hoeflich; Zahara M Jaffer; Adrian M Jubb; Andres J P Klein-Szanto; Jennifer N Koch; Marie O'Farrell; Dina Stepanova; Kathy Q Cai; David A Campbell; Jonathan Chernoff
p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.

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All Publications

2013: Sonali Jalan Rawat; Caretha L Creasy; Jeffrey R Peterson; Jonathan Chernoff
The tumor suppressor Mst1 promotes changes in the cellular redox state by phosphorylation and inactivation of peroxiredoxin-1 protein.
The Journal of biological chemistry 2013;288(12):8762-71.
2013: Rachelle Kosoff; Maria Radu; Hoi Yee Chow; Jonathan Chernoff
Pak2 kinase restrains mast cell FcεRI receptor signaling through modulation of Rho protein guanine nucleotide exchange factor (GEF) activity.
The Journal of biological chemistry 2013;288(2):974-83.
2012: Hoi Yee Chow; Sergio G Duron; J Silvio Gutkind; Klaus P Hoeflich; Zahara M Jaffer; Adrian M Jubb; Andres J P Klein-Szanto; Jennifer N Koch; Marie O'Farrell; Dina Stepanova; Kathy Q Cai; David A Campbell; Jonathan Chernoff
p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.
Cancer research 2012;72(22):5966-75.
2012: Craig W Menges; Jeffrey Peterson; Eleonora Sementino; Jacqueline Talarchek; Jonathan Chernoff; Jinfei Xu; Joseph R Testa
Group I p21-activated kinases (PAKs) promote tumor cell proliferation and survival through the AKT1 and Raf-MAPK pathways.
Molecular cancer research : MCR 2012;10(9):1178-88.
2012: Galina Semenova; Jonathan Chernoff
PKM2 enters the morpheein academy.
Molecular cell 2012;45(5):583-4.
2012: Shu-Chin Yip; Sophie Cotteret; Jonathan Chernoff
Sumoylated protein tyrosine phosphatase 1B localizes to the inner nuclear membrane and regulates the tyrosine phosphorylation of emerin.
Journal of cell science 2012;125(Pt 2):310-6.
2012: Wyn C Hoover; Zhidong Xue; Wenwu Zhang; Jonathan Chernoff; D Wade Clapp; Huanling Gao; Susan J Gunst; Robert S Tepper
Inhibition of p21 activated kinase (PAK) reduces airway responsiveness in vivo and in vitro in murine and human airways.
PloS one 2012;7(8):e42601.
2012: Krishna A Jhaveri; J Sanders; Jonathan Chernoff; P Debnath; Martin A Schwartz
The role of p21-activated kinase in the initiation of atherosclerosis.
BMC cardiovascular disorders 2012;12():55.
2011: Igor Makhlin; Jiaru Zhang; Yan Zhou; Jonathan Chernoff; Karthik Devarajan; Min Huang; Andres J Klein-Szanto; Christopher J Long; Stephen A Boorjian
The mTOR pathway affects proliferation and chemosensitivity of urothelial carcinoma cells and is upregulated in a subset of human bladder cancers.
BJU international 2011;108(2 Pt 2):E84-90.
2011: Mollie L Kelly; Jonathan Chernoff
Getting smart about p21-activated kinases.
Molecular and cellular biology 2011;31(3):386-7.
2011: C Van den Broeke; M Radu; Hans J Nauwynck; Jonathan Chernoff; Herman W Favoreel
Role of group A p21-activated kinases in the anti-apoptotic activity of the pseudorabies virus US3 protein kinase.
Virus research 2011;155(1):376-80.
2010: Luis Enrique Arias-Romero; Olga Villamar-Cruz; A Pacheco; R Kosoff; M Huang; S K Muthuswamy; Jonathan Chernoff
A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells.
Oncogene 2010;29(43):5839-49.
2010: Shu-Chin Yip; Sayanti Saha; Jonathan Chernoff
PTP1B: a double agent in metabolism and oncogenesis.
Trends in biochemical sciences 2010;35(8):442-9.
2010: Poonam R Molli; Da-Qiang Li; Rozita Bagheri-Yarmand; Suresh B Pakala; Hiroshi Katayama; Subrata Sen; Jyoti Iyer; Jonathan Chernoff; Ming-Ying Tsai; Sujit S Nair; Rakesh Kumar
Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A.
The Journal of cell biology 2010;190(1):101-14.
2010: Celine Van den Broeke; Maria Radu; Jonathan Chernoff; Herman W Favoreel
An emerging role for p21-activated kinases (Paks) in viral infections.
Trends in cell biology 2010;20(3):160-9.
2010: Hoi Yee Chow; Dina Stepanova; Jennifer Koch; Jonathan Chernoff
p21-Activated kinases are required for transformation in a cell-based model of neurofibromatosis type 2.
PloS one 2010;5(11):e13791.
2010: Almudena Pacheco; Jonathan Chernoff
Group I p21-activated kinases: emerging roles in immune function and viral pathogenesis.
The international journal of biochemistry & cell biology 2010;42(1):13-6.
2009: Christine Flaiz; Jonathan Chernoff; Sylwia Ammoun; Jeffrey Peterson; C Oliver Hanemann
PAK kinase regulates Rac GTPase and is a potential target in human schwannomas.
Experimental neurology 2009;218(1):137-44.
2009: Luis Enrique Arias-Romero; Sayanti Saha; Olga Villamar-Cruz; Shu-Chin Yip; Stephen Ethier; Zhong-Yin Zhang; Jonathan Chernoff
Activation of Src by protein tyrosine phosphatase 1B Is required for ErbB2 transformation of human breast epithelial cells.
Cancer research 2009;69(11):4582-8.
2009: Maria Radu; Jonathan Chernoff
The DeMSTification of mammalian Ste20 kinases.
Current biology : CB 2009;19(10):R421-5.
2009: Céline Van den Broeke; Maria Radu; Matthias Deruelle; Hans Nauwynck; Clemens Hofmann; Zahara M Jaffer; Jonathan Chernoff; Herman W Favoreel
Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(21):8707-12.
2009: Jayme D Allen; Zahara M Jaffer; Su-Jung Park; Sarah Burgin; Clemens Hofmann; Mary Ann Sells; Shi Chen; Ethel Derr-Yellin; Elizabeth G Michels; Andrew McDaniel; Waylan K Bessler; David A Ingram; Simon J Atkinson; Jeffrey B Travers; Jonathan Chernoff; D Wade Clapp
p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics.
Blood 2009;113(12):2695-705.
2009: Christine M Lightcap; Gabor Kari; Luis Enrique Arias-Romero; Jonathan Chernoff; Ulrich Rodeck; John C Williams
Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development.
PloS one 2009;4(6):e6025.
2008: Andrew S McDaniel; Jayme D Allen; Su-Jung Park; Zahara M Jaffer; Elizabeth G Michels; Sarah J Burgin; Shi Chen; Waylan K Bessler; Clemens Hofmann; David A Ingram; Jonathan Chernoff; D Wade Clapp
Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells.
Blood 2008;112(12):4646-54.
2008: Stephen D Smith; Zahara M Jaffer; Jonathan Chernoff; Anne J Ridley
PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics.
Journal of cell science 2008;121(Pt 22):3729-36.
2008: Sean W Deacon; Alexander Beeser; Jami A Fukui; Ulrike E E Rennefahrt; Cynthia Myers; Jonathan Chernoff; Jeffrey Peterson
An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase.
Chemistry & biology 2008;15(4):322-31.
2008: Luis Enrique Arias-Romero; Jonathan Chernoff
A tale of two Paks.
Biology of the cell / under the auspices of the European Cell Biology Organization 2008;100(2):97-108.
2008: Kai Mao; Satoru Kobayashi; Zahara M Jaffer; Yuan Huang; Paul Volden; Jonathan Chernoff; Qiangrong Liang
Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes.
Journal of molecular and cellular cardiology 2008;44(2):429-34.
2007: Julie C Friedland; Johnathon N Lakins; Marcelo G Kazanietz; Jonathan Chernoff; David Boettiger; Valerie M Weaver
alpha6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-kappaB-dependent resistance to apoptosis in 3D mammary acini.
Journal of cell science 2007;120(Pt 20):3700-12.
2007: Ulrike E E Rennefahrt; Sean W Deacon; Sirlester A Parker; Karthik Devarajan; Alexander Beeser; Jonathan Chernoff; Stefan Knapp; Benjamin E Turk; Jeffrey Peterson
Specificity profiling of Pak kinases allows identification of novel phosphorylation sites.
The Journal of biological chemistry 2007;282(21):15667-78.
2007: Minna Thullberg; Annica Gad; Alexander Beeser; Jonathan Chernoff; Staffan Strömblad
The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity.
Oncogene 2007;26(12):1820-8.
2007: Shrikrishna Dadke; Sophie Cotteret; Shu-Chin Yip; Zahara M Jaffer; Fawaz G Haj; Alexey Ivanov; Frank Rauscher; Ke Shuai; Tony Ng; Benjamin G Neel; Jonathan Chernoff
Regulation of protein tyrosine phosphatase 1B by sumoylation.
Nature cell biology 2007;9(1):80-5.
2006: Jeffrey Peterson; Jonathan Chernoff
Src transforms in a Cool way.
Nature cell biology 2006;8(9):905-7.
2006: Michelle Pirruccello; Holger Sondermann; Jeffrey G Pelton; Patricia Pellicena; André Hoelz; Jonathan Chernoff; David E Wemmer; John Kuriyan
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases.
Journal of molecular biology 2006;361(2):312-26.
2006: Sophie Cotteret; Jonathan Chernoff
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties.
Molecular and cellular biology 2006;26(8):3215-30.
2006: Jean Paul ten Klooster; Zahara M Jaffer; Jonathan Chernoff; Peter L Hordijk
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
The Journal of cell biology 2006;172(5):759-69.
2005: Peter J Bartholomew; Christopher W Jones; Angela Benware; Jonathan Chernoff; Susan E LaFlamme
Regulation of the catalytic activity of PTP1B: roles for cell adhesion, tyrosine residue 66, and proline residues 309 and 310.
Experimental cell research 2005;311(2):294-306.
2005: Alexander Beeser; Zahara M Jaffer; Clemens Hofmann; Jonathan Chernoff
Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors.
The Journal of biological chemistry 2005;280(44):36609-15.
2005: Shiqing Li; Rafael S Depetris; David Barford; Jonathan Chernoff; Stevan Hubbard
Crystal structure of a complex between protein tyrosine phosphatase 1B and the insulin receptor tyrosine kinase.
Structure (London, England : 1993) 2005;13(11):1643-51.
2005: Sophie Cotteret; Jonathan Chernoff
Pak GITs to Aurora-A.
Developmental cell 2005;9(5):573-4.
2005: Alexander Beeser; Jonathan Chernoff
Production and use of a cell permeable inhibitor of group A Paks (TAT-PID) to analyze signal transduction.
Methods (San Diego, Calif.) 2005;37(2):203-7.
2005: Tina M Leisner; Mingjuan Liu; Zahara M Jaffer; Jonathan Chernoff; Leslie V Parise
Essential role of CIB1 in regulating PAK1 activation and cell migration.
The Journal of cell biology 2005;170(3):465-76.
2005: Anatilde M Gonzalez Guerrico; Zahara M Jaffer; Robert E Page; Karl-Heinz Braunewell; Jonathan Chernoff; Andres J P Klein-Szanto
Visinin-like protein-1 is a potent inhibitor of cell adhesion and migration in squamous carcinoma cells.
Oncogene 2005;24(14):2307-16.
2005: Maddy Parsons; James Monypenny; Simon M Ameer-Beg; Thomas H Millard; Laura M Machesky; Marion Peter; Melanie D Keppler; Giampietro Schiavo; Rose Watson; Jonathan Chernoff; Daniel Zicha; Borivoj Vojnovic; Tony Ng
Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells.
Molecular and cellular biology 2005;25(5):1680-95.
2005: Elena M Sorokina; Jonathan Chernoff
Rho-GTPases: new members, new pathways.
Journal of cellular biochemistry 2005;94(2):225-31.
2004: Clemens Hofmann; Mikhail Shepelev; Jonathan Chernoff
The genetics of Pak.
Journal of cell science 2004;117(Pt 19):4343-54.
2004: Zahara M Jaffer; Jonathan Chernoff
The cross-Rho'ds of cell-cell adhesion.
The Journal of biological chemistry 2004;279(34):35123-6.
2004: Lucinda F Reynolds; Carine de Bettignies; Trisha Norton; Alexander Beeser; Jonathan Chernoff; Victor L J Tybulewicz
Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1.
The Journal of biological chemistry 2004;279(18):18239-46.
2004: Erica A Golemis; Jonathan Chernoff
Analysis and manipulation of intracellular signaling cascades.
Methods (San Diego, Calif.) 2004;32(4):347-8.
2003: Shrikrishna Dadke; Jonathan Chernoff
Protein-tyrosine phosphatase 1B as a potential drug target for obesity.
Current drug targets. Immune, endocrine and metabolic disorders 2003;3(4):299-304.
2003: Guang-Hui Xiao; Jonathan Chernoff; Joseph R Testa
NF2: the wizardry of merlin.
Genes, chromosomes & cancer 2003;38(4):389-99.
2003: Shrikrishna Dadke; Jonathan Chernoff
Protein-tyrosine phosphatase 1B mediates the effects of insulin on the actin cytoskeleton in immortalized fibroblasts.
The Journal of biological chemistry 2003;278(42):40607-11.
2003: Dongpo Cai; Anita Iyer; Kyriacos Felekkis; Richard I Near; Zhijun Luo; Jonathan Chernoff; Chris Albanese; Richard G Pestell; Adam Lerner
AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter.
Cancer research 2003;63(20):6802-8.
2003: Mirjam M P Zegers; Marie-Annick Forget; Jonathan Chernoff; Keith E Mostov; Martin B A ter Beest; Steen H Hansen
Pak1 and PIX regulate contact inhibition during epithelial wound healing.
The EMBO journal 2003;22(16):4155-65.
2003: Sophie Cotteret; Zahara M Jaffer; Alexander Beeser; Jonathan Chernoff
p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD.
Molecular and cellular biology 2003;23(16):5526-39.
2003: Wang L Cheung; Kozo Ajiro; Kumiko Samejima; Malgorzata Kloc; Peter Cheung; Craig A Mizzen; Alexander Beeser; Laurence D Etkin; Jonathan Chernoff; William C Earnshaw; C David Allis
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase.
Cell 2003;113(4):507-17.
2003: Karl Deacon; Pratibha Mistry; Jonathan Chernoff; Jonathan L Blank; Rajnikant Patel
p38 Mitogen-activated protein kinase mediates cell death and p21-activated kinase mediates cell survival during chemotherapeutic drug-induced mitotic arrest.
Molecular biology of the cell 2003;14(5):2071-87.
2003: Jude Anne Cassidy; Julie Wargo Aikins; Jonathan Chernoff
Children's peer selection: experimental examination of the role of self-perceptions.
Developmental psychology 2003;39(3):495-508.
2003: Peter Penzes; Alexander Beeser; Jonathan Chernoff; Martin R Schiller; Betty A Eipper; Richard E Mains; Richard Huganir
Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin.
Neuron 2003;37(2):263-74.
2002: Aristotelis Astrinidis; Timothy P Cash; Deborah S Hunter; Cheryl Lyn Walker; Jonathan Chernoff; Elizabeth Petri Henske
Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration.
Oncogene 2002;21(55):8470-6.
2002: Margareta Nikolic; Jonathan Chernoff
High midsummer for small GTPases.
Trends in cell biology 2002;12(11):495-7.
2002: Ilya G Serebriiskii; Olga Mitina; Elena N Pugacheva; Elizaveta V. Benevolenskay; Elena Kotova; Garabet G Toby; Vladimir Khazak; William G Kaelin; Jonathan Chernoff; Erica A Golemis
Detection of peptides, proteins, and drugs that selectively interact with protein targets.
Genome research 2002;12(11):1785-91.
2002: Feng Li; Liana Adam; Ratna K Vadlamudi; Hongyi Zhou; Subrata Sen; Jonathan Chernoff; Mahitosh Mandal; Rakesh Kumar
p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells.
EMBO reports 2002;3(8):767-73.
2002: Debra A Thiel; Melissa Kirk; Amanda Pfaff; Thomas R Coleman; Mary Ann Sells; Jonathan Chernoff
Cell cycle-regulated phosphorylation of p21-activated kinase 1.
Current biology : CB 2002;12(14):1227-32.
2002: Zahara M Jaffer; Jonathan Chernoff
p21-activated kinases: three more join the Pak.
The international journal of biochemistry & cell biology 2002;34(7):713-7.
2002: Shrikrishna Dadke; Jonathan Chernoff
Interaction of protein tyrosine phosphatase (PTP) 1B with its substrates is influenced by two distinct binding domains.
The Biochemical journal 2002;364(Pt 2):377-83.
2002: Guang-Hui Xiao; Alexander Beeser; Jonathan Chernoff; Joseph R Testa
p21-activated kinase links Rac/Cdc42 signaling to merlin.
The Journal of biological chemistry 2002;277(2):883-6.
2002: Sophie Cotteret; Jonathan Chernoff
The evolutionary history of effectors downstream of Cdc42 and Rac.
Genome biology 2002;3(2):REVIEWS0002.
2001: Melissa Kirk; Ilya G Serebriiskii; Erica A Golemis; Jonathan Chernoff
Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42.
The Journal of biological chemistry 2001;276(44):40606-13.
2001: M Mota; Melissa Kirk; Jonathan Chernoff; CE Bazenet
Evidence for a role of mixed lineage kinases in neuronal apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(14):4949-57.
2001: Ilya G Serebriiskii; O V Mitina; Jonathan Chernoff; Erica A Golemis
Two-hybrid dual bait system to discriminate specificity of protein interactions in small GTPases.
Methods in enzymology 2001;332():277-300.
2000: Mary Ann Sells; A Pfaff; Jonathan Chernoff
Temporal and spatial distribution of activated Pak1 in fibroblasts.
The Journal of cell biology 2000;151(7):1449-58.
2000: Vivek K Arora; R P Molina; John L Foster; J L Blakemore; Jonathan Chernoff; Brenda L Fredericksen; Jose Garcia-Martinez
Lentivirus Nef specifically activates Pak2.
Journal of virology 2000;74(23):11081-7.
2000: Ratna K Vadlamudi; Liana Adam; Rui-An Wang; Mahitosh Mandal; Diep Nguyen; Aysegul Sahin; Jonathan Chernoff; Mien-Chie Hung; Rakesh Kumar
Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells.
The Journal of biological chemistry 2000;275(46):36238-44.
2000: S Dharmawardhane; Annette Schürmann; Mary Ann Sells; Jonathan Chernoff; Sandra L Schmid; Gary M Bokoch
Regulation of macropinocytosis by p21-activated kinase-1.
Molecular biology of the cell 2000;11(10):3341-52.
2000: Shrikrishna Dadke; J Kusari; Jonathan Chernoff
Down-regulation of insulin signaling by protein-tyrosine phosphatase 1B is mediated by an N-terminal binding region.
The Journal of biological chemistry 2000;275(31):23642-7.
2000: Liana Adam; Ratna K Vadlamudi; Mahitosh Mandal; Jonathan Chernoff; Rakesh Kumar
Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1.
The Journal of biological chemistry 2000;275(16):12041-50.
2000: Aline Valster; Peter K Hepler; Jonathan Chernoff
Plant GTPases: the Rhos in bloom.
Trends in cell biology 2000;10(4):141-6.
1999: Jonathan Chernoff
Close encounters of the LIM-kinase.
Nature cell biology 1999;1(5):E115-7.
1999: Jonathan Chernoff
Protein tyrosine phosphatases as negative regulators of mitogenic signaling.
Journal of cellular physiology 1999;180(2):173-81.
1999: Mary Ann Sells; Jonathan T Boyd; Jonathan Chernoff
p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts.
The Journal of cell biology 1999;145(4):837-49.
1998: J Bubeck Wardenburg; R Pappu; J Y Bu; B Mayer; Jonathan Chernoff; D Straus; A C Chan
Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76.
Immunity 1998;9(5):607-16.
1998: Liana Adam; Ratna K Vadlamudi; S B Kondapaka; Jonathan Chernoff; John Mendelsohn; Rakesh Kumar
Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase.
The Journal of biological chemistry 1998;273(43):28238-46.
1998: Mary Ann Sells; J T Barratt; J Caviston; S Ottilie; E Leberer; Jonathan Chernoff
Characterization of Pak2p, a pleckstrin homology domain-containing, p21-activated protein kinase from fission yeast.
The Journal of biological chemistry 1998;273(29):18490-8.
1998: Jonathan D Graves; Y Gotoh; Kevin E Draves; DM Ambrose; David K Han; M Wright; Jonathan Chernoff; Edward A Clark; Edwin G Krebs
Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1.
The EMBO journal 1998;17(8):2224-34.
1998: Baolin Zhang; Jonathan Chernoff; Yi Zheng
Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA.
The Journal of biological chemistry 1998;273(15):8776-82.
1998: F Liu; Mary Ann Sells; Jonathan Chernoff
Protein tyrosine phosphatase 1B negatively regulates integrin signaling.
Current biology : CB 1998;8(3):173-6.
1998: F Liu; Mary Ann Sells; Jonathan Chernoff
Transformation suppression by protein tyrosine phosphatase 1B requires a functional SH3 ligand.
Molecular and cellular biology 1998;18(1):250-9.
1997: F Liu; Jonathan Chernoff
Protein tyrosine phosphatase 1B interacts with and is tyrosine phosphorylated by the epidermal growth factor receptor.
The Biochemical journal 1997;327 ( Pt 1)():139-45.
1997: Y Tang; Z Chen; DM Ambrose; J Liu; Jackson B Gibbs; Jonathan Chernoff; Jeffrey Field
Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts.
Molecular and cellular biology 1997;17(8):4454-64.
1997: Mary Ann Sells; Jonathan Chernoff
Emerging from the Pak: the p21-activated protein kinase family.
Trends in cell biology 1997;7(4):162-7.
1997: Mary Ann Sells; U G Knaus; S Bagrodia; DM Ambrose; Gary M Bokoch; Jonathan Chernoff
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells.
Current biology : CB 1997;7(3):202-10.
1997: D Bandyopadhyay; AB Kusari; KA Kenner; F Liu; Jonathan Chernoff; TA Gustafson; J Kusari
Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin.
The Journal of biological chemistry 1997;272(3):1639-45.
1997: Janet C Frank; Susan H Hirsch; Jonathan Chernoff; S P Wallace; A Abrahamse; Rose C Maly; David B Reuben
Determinants of patient adherence to consultative comprehensive geriatric assessment recommendations.
The journals of gerontology. Series A, Biological sciences and medical sciences 1997;52(1):M44-51.
1996: F Liu; David E Hill; Jonathan Chernoff
Direct binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src homology 3 domain of p130(Cas).
The Journal of biological chemistry 1996;271(49):31290-5.
1996: M L Galisteo; Jonathan Chernoff; YC Su; Edward Y Skolnik; Joseph Schlessinger
The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1.
The Journal of biological chemistry 1996;271(35):20997-1000.
1996: C L Creasy; D M Ambrose; Jonathan Chernoff
The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain.
The Journal of biological chemistry 1996;271(35):21049-53.
1995: C L Creasy; Jonathan Chernoff
Cloning and characterization of a member of the MST subfamily of Ste20-like kinases.
Gene 1995;167(1-2):303-6.
1995: S Ottilie; P J Miller; D I Johnson; C L Creasy; Mary Ann Sells; Shubha Bagrodia; Susan Forsburg; Jonathan Chernoff
Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating.
The EMBO journal 1995;14(23):5908-19.
1995: V Vambutas; D R Kaplan; Mary Ann Sells; Jonathan Chernoff
Nerve growth factor stimulates tyrosine phosphorylation and activation of Src homology-containing protein-tyrosine phosphatase 1 in PC12 cells.
The Journal of biological chemistry 1995;270(43):25629-33.
1995: S Zhang; Jiahuai Han; Mary Ann Sells; Jonathan Chernoff; Ulla G Knaus; Richard J Ulevitch; Gary M Bokoch
Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.
The Journal of biological chemistry 1995;270(41):23934-6.
1995: Shubha Bagrodia; S J Taylor; C L Creasy; Jonathan Chernoff; Richard A Cerione
Identification of a mouse p21Cdc42/Rac activated kinase.
The Journal of biological chemistry 1995;270(39):22731-7.
1995: C L Creasy; Jonathan Chernoff
Cloning and characterization of a human protein kinase with homology to Ste20.
The Journal of biological chemistry 1995;270(37):21695-700.
1995: Ulla G Knaus; S Morris; H J Dong; Jonathan Chernoff; Gary M Bokoch
Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors.
Science (New York, N.Y.) 1995;269(5221):221-3.
1995: Mary Ann Sells; J Li; Jonathan Chernoff
Delivery of protein into cells using polycationic liposomes.
BioTechniques 1995;19(1):72-6, 78.
1995: Mary Ann Sells; Jonathan Chernoff
Epitope-tag vectors for eukaryotic protein production.
Gene 1995;152(2):187-9.
1995: Mary Ann Sells; Jonathan Chernoff
Polymerase chain reaction cloning of related genes.
Methods in enzymology 1995;254():184-95.
1994: Christos Patriotis; A Makris; Jonathan Chernoff; Philip Tsichlis
Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9755-9.
1993: David B Reuben; Susan H Hirsch; Jonathan Chernoff; Y Cheska; Marc K Drezner; B Engelman; Janet C Frank; M Schlesinger; C F Siegler
Project Safety Net: a health screening outreach and assessment program.
The Gerontologist 1993;33(4):557-60.
1992: S Ottilie; Jonathan Chernoff; G Hannig; Charles Hoffman; Raymond L. Erikson
The fission yeast genes pyp1+ and pyp2+ encode protein tyrosine phosphatases that negatively regulate mitosis.
Molecular and cellular biology 1992;12(12):5571-80.
1991: S Ottilie; Jonathan Chernoff; G Hannig; Charles Hoffman; Raymond L. Erikson
A fission-yeast gene encoding a protein with features of protein-tyrosine-phosphatases.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3455-9.
1990: Jonathan Chernoff; A R Schievella; C A Jost; Raymond L. Erikson; Benjamin G Neel
Cloning of a cDNA for a major human protein-tyrosine-phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(7):2735-9.
1985: Jonathan Chernoff; H C Li
A major phosphotyrosyl-protein phosphatase from bovine heart is associated with a low-molecular-weight acid phosphatase.
Archives of biochemistry and biophysics 1985;240(1):135-45.
1985: Mary Ann Sells; Jonathan Chernoff; A Cerda; C Bowers; David A Shafritz; N Kase; J K Christman; G Acs
Long-term culture and passage of human fetal liver cells that synthesize albumin.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1985;21(4):216-20.
1984: Jonathan Chernoff; Mary Ann Sells; H C Li
Characterization of phosphotyrosyl-protein phosphatase activity associated with calcineurin.
Biochemical and biophysical research communications 1984;121(1):141-8.
1984: H C Li; Jonathan Chernoff; L B Chen; A Kirschonbaum
A phosphotyrosyl-protein phosphatase activity associated with acid phosphatase from human prostate gland.
European journal of biochemistry / FEBS 1984;138(1):45-51.
1983: Jonathan Chernoff; H C Li
Multiple forms of phosphotyrosyl- and phosphoseryl-protein phosphatase from cardiac muscle: partial purification and characterization of an EDTA-stimulated phosphotyrosyl-protein phosphatase.
Archives of biochemistry and biophysics 1983;226(2):517-30.
1983: Jonathan Chernoff; H C Li; Y S Cheng; L B Chen
Characterization of a phosphotyrosyl protein phosphatase activity associated with a phosphoseryl protein phosphatase of Mr = 95,000 from bovine heart.
The Journal of biological chemistry 1983;258(12):7852-7.