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Abdel Naser La Rezk

Research Profile

Chemicals & Drugs

Disorders

HIV Infections

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HIV-1

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Publications

TOP 3
Julie Dumond; M Vourvahis; Abdel Naser La Rezk; Kristine B Patterson; Hsiao-Chuan Tien; N White; S H Jennings; S O Choi; J Li; M J Wagner; N M La-Beck; M Drulak; J P Sabo; M A Castles; T R Macgregor; Angela D M Kashuba
A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir.
S O Choi; Abdel Naser La Rezk; J S Kim; Angela D M Kashuba
Development of an LC-MS method for measuring TNF in human vaginal tissue.
Amanda H Corbett; Mina Hosseinipour; Jean Nyirenda; Cecelia Kanyama; Abdel Naser La Rezk; Pax Mkupani; Dorothy Sichali; Hsiao Tien; Angela D M Kashuba; Charles Mwansambo; Ralf Weigel; Peter N Kazembe
Pharmacokinetics of generic and trade formulations of lamivudine, stavudine and nevirapine in HIV-infected Malawian children.

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All Publications

2010: Julie Dumond; M Vourvahis; Abdel Naser La Rezk; Kristine B Patterson; Hsiao-Chuan Tien; N White; S H Jennings; S O Choi; J Li; M J Wagner; N M La-Beck; M Drulak; J P Sabo; M A Castles; T R Macgregor; Angela D M Kashuba
A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir.
Clinical pharmacology and therapeutics 2010;87(6):735-42.
2010: S O Choi; Abdel Naser La Rezk; J S Kim; Angela D M Kashuba
Development of an LC-MS method for measuring TNF in human vaginal tissue.
Journal of chromatographic science 2010;48(3):219-23.
2010: Amanda H Corbett; Mina Hosseinipour; Jean Nyirenda; Cecelia Kanyama; Abdel Naser La Rezk; Pax Mkupani; Dorothy Sichali; Hsiao Tien; Angela D M Kashuba; Charles Mwansambo; Ralf Weigel; Peter N Kazembe
Pharmacokinetics of generic and trade formulations of lamivudine, stavudine and nevirapine in HIV-infected Malawian children.
Antiviral therapy 2010;15(1):83-90.
2010: MaryPeace McRae; Abdel Naser La Rezk; Arlene Bridges; Amanda H Corbett; Hsiao-Chuan Tien; Kim L R Brouwer; Angela D M Kashuba
Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicity.
Pharmacotherapy 2010;30(1):17-24.
2010: Jasmine A Talameh; Abdel Naser La Rezk; Angela D M Kashuba
Quantifying the HIV-1 integrase inhibitor raltegravir in female genital tract secretions using high-performance liquid chromatography with ultraviolet detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(1):92-6.
2009: Abdel Naser La Rezk; Nicole R White; Steven H Jennings; Angela D M Kashuba
A novel LC-ESI-MS method for the simultaneous determination of etravirine, darunavir and ritonavir in human blood plasma.
Talanta 2009;79(5):1372-8.
2009: Paul Leger; Rebecca Dillingham; Carole Anne Beauharnais; Angela D M Kashuba; Abdel Naser La Rezk; Daniel W Fitzgerald; Jean William Pape; David W Haas
CYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Port-au-Prince, Haiti.
The Journal of infectious diseases 2009;200(6):955-64.
2009: Awewura Kwara; Margaret Lartey; Isaac Boamah; Abdel Naser La Rezk; Joseph Oliver-Commey; Ernest Kenu; Angela D M Kashuba; Michael H Court
Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidation.
Journal of clinical pharmacology 2009;49(9):1079-90.
2009: Shailesh K Choudhary; Abdel Naser La Rezk; William L Ince; Manzoor Cheema; L Zhang; Lishan Su; Ronald Swanstrom; Angela D M Kashuba; David M Margolis
Suppression of human immunodeficiency virus type 1 (HIV-1) viremia with reverse transcriptase and integrase inhibitors, CD4+ T-cell recovery, and viral rebound upon interruption of therapy in a new model for HIV treatment in the humanized Rag2-/-{gamma}c-/- mouse.
Journal of virology 2009;83(16):8254-8.
2009: Rosa F Yeh; Abdel Naser La Rezk; Angela D M Kashuba; Julie Dumond; Hiba L Tappouni; Hsiao-Chuan Tien; Ya-Chi Chen; Manoli Vourvahis; Amanda L Horton; Susan A Fiscus; Kristine B Patterson
Genital tract, cord blood, and amniotic fluid exposures of seven antiretroviral drugs during and after pregnancy in human immunodeficiency virus type 1-infected women.
Antimicrobial agents and chemotherapy 2009;53(6):2367-74.
2008: Abdel Naser La Rezk; Nicole White; Angela D M Kashuba
An accurate and precise high-performance liquid chromatography method for the rapid quantification of the novel HIV integrase inhibitor raltegravir in human blood plasma after solid phase extraction.
Analytica chimica acta 2008;628(2):204-13.
2008: Abdel Naser La Rezk; Nicole White; Arlene Bridges; Mohamed F Abdel-Megeed; Tarek M Mohamed; Said S Moselhy; Angela D M Kashuba
Studies on antiretroviral drug concentrations in breast milk: validation of a liquid chromatography-tandem mass spectrometric method for the determination of 7 anti-human immunodeficiency virus medications.
Therapeutic drug monitoring 2008;30(5):611-9.
2008: Robert DiCenzo; Derick R Peterson; Kim Cruttenden; Peter Mariuz; Abdel Naser La Rezk; Jill Hochreiter; Harris Gelbard; Giovanni Schifitto
Effects of minocycline and valproic acid coadministration on atazanavir plasma concentrations in human immunodeficiency virus-infected adults receiving atazanavir-ritonavir.
Antimicrobial agents and chemotherapy 2008;52(9):3035-9.
2008: Martin Cranage; Sally Sharpe; Carolina Herrera; Alethea Cope; Mike Dennis; Neil Berry; Claire Ham; Jonathan Luke Heeney; Abdel Naser La Rezk; Angela D M Kashuba; Peter A Anton; Ian McGowan; Robin J Shattock
Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel.
PLoS medicine 2008;5(8):e157; discussion e157.
2008: Hiba L Tappouni; John C Rublein; Brian J Donovan; Stephanie B Hollowell; Hsiao-Chuan Tien; Sherene S Min; Dickens Theodore; Abdel Naser La Rezk; Philip C Smith; Melanie N Tallman; Ralph H Raasch; Angela D M Kashuba
Effect of omeprazole on the plasma concentrations of indinavir when administered alone and in combination with ritonavir.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2008;65(5):422-8.
2008: Awewura Kwara; Allison Delong; Abdel Naser La Rezk; Joseph Hogan; Heather Burtwell; Stacy Chapman; Carla C Moreira; Jaclynn Kurpewski; Jessica Ingersoll; Angela M Caliendo; Angela D M Kashuba; Susan Cu-Uvin
Antiretroviral drug concentrations and HIV RNA in the genital tract of HIV-infected women receiving long-term highly active antiretroviral therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;46(5):719-25.
2008: Manoli Vourvahis; Hiba L Tappouni; Kristine B Patterson; Ya-Chi Chen; Abdel Naser La Rezk; Susan A Fiscus; Brian P Kearney; James F Rooney; James Hui; Myron S Cohen; Angela D M Kashuba
The pharmacokinetics and viral activity of tenofovir in the male genital tract.
Journal of acquired immune deficiency syndromes (1999) 2008;47(3):329-33.
2007: Byung Hwa Jung; Abdel Naser La Rezk; Arlene Bridges; Amanda H Corbett; Angela D M Kashuba
Simultaneous determination of 17 antiretroviral drugs in human plasma for quantitative analysis with liquid chromatography-tandem mass spectrometry.
Biomedical chromatography : BMC 2007;21(10):1095-104.
2007: Julie Dumond; Rosa F Yeh; Kristine B Patterson; Amanda H Corbett; Byung Hwa Jung; Abdel Naser La Rezk; Arlene Bridges; Paul W. Stewart; Myron S Cohen; Angela D M Kashuba
Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis.
AIDS (London, England) 2007;21(14):1899-907.
2007: Abdel Naser La Rezk; Mohamed F Abdel-Megeed; Angela D M Kashuba
Development of a highly efficient extraction technique and specific multiplex assay for measuring antiretroviral drug concentrations in breast milk.
Therapeutic drug monitoring 2007;29(4):429-36.
2007: Sun Ok Choi; Abdel Naser La Rezk; Angela D M Kashuba
High-performance liquid chromatography assay for the determination of the HIV-protease inhibitor tipranavir in human plasma in combination with nine other antiretroviral medications.
Journal of pharmaceutical and biomedical analysis 2007;43(4):1562-7.
2007: Mina Hosseinipour; Amanda H Corbett; Cecelia Kanyama; Idah Mshali; Severiano Phakati; Abdel Naser La Rezk; Charles van der Horst; Angela D M Kashuba
Pharmacokinetic comparison of generic and trade formulations of lamivudine, stavudine and nevirapine in HIV-infected Malawian adults.
AIDS (London, England) 2007;21(1):59-64.
2006: Abdel Naser La Rezk; Kevin C Brown; Angela D M Kashuba
A simple and sensitive bioanalytical assay for simultaneous determination of omeprazole and its three major metabolites in human blood plasma using RP-HPLC after a simple liquid-liquid extraction procedure.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;844(2):314-21.
2006: Abdel Naser La Rezk; Rustin D Crutchley; Rosa F Yeh; Angela D M Kashuba
Full validation of an analytical method for the HIV-protease inhibitor atazanavir in combination with 8 other antiretroviral agents and its applicability to therapeutic drug monitoring.
Therapeutic drug monitoring 2006;28(4):517-25.
2006: Rosa F Yeh; Vincent E Gaver; Kristine B Patterson; Abdel Naser La Rezk; Faustina Baxter-Meheux; Michael J Blake; Joseph J Eron; Cheri E Klein; John C Rublein; Angela D M Kashuba
Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers.
Journal of acquired immune deficiency syndromes (1999) 2006;42(1):52-60.
2005: Abdel Naser La Rezk; Rustin D Crutchley; Angela D M Kashuba
Simultaneous quantification of emtricitabine and tenofovir in human plasma using high-performance liquid chromatography after solid phase extraction.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;822(1-2):201-8.
2004: Sherene S Min; Amanda H Corbett; Abdel Naser La Rezk; Susan Cu-Uvin; Susan A Fiscus; Leslie Petch; Myron S Cohen; Angela D M Kashuba
Protease inhibitor and nonnucleoside reverse transcriptase inhibitor concentrations in the genital tract of HIV-1-infected women.
Journal of acquired immune deficiency syndromes (1999) 2004;37(5):1577-80.
2004: Amanda H Corbett; Joseph J Eron; Susan A Fiscus; Abdel Naser La Rezk; Angela D M Kashuba
The pharmacokinetics, safety, and initial virologic response of a triple-protease inhibitor salvage regimen containing amprenavir, saquinavir, and ritonavir.
Journal of acquired immune deficiency syndromes (1999) 2004;36(4):921-8.
2004: Abdel Naser La Rezk; Richard R Tidwell; Angela D M Kashuba
High-performance liquid chromatography assay for the quantification of HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors in human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;805(2):241-7.
2003: Abdel Naser La Rezk; Richard R Tidwell; Angela D M Kashuba
Simultaneous determination of six HIV nucleoside analogue reverse transcriptase inhibitors and nevirapine by liquid chromatography with ultraviolet absorbance detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;791(1-2):137-47.
2002: Abdel Naser La Rezk; Richard R Tidwell; Angela D M Kashuba
Simple and rapid quantification of the non-nucleoside reverse transcriptase inhibitors nevirapine, delavirdine, and efavirenz in human blood plasma using high-performance liquid chromatography with ultraviolet absorbance detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;774(1):79-88.