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Richard Carp

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B-H Jeong; H-T Jin; Richard I Carp; Yong-Sun Kim
Bovine spongiform encephalopathy (BSE)-associated polymorphisms of the prion protein (PRNP) gene in Korean native cattle.
Yong-Chul Jeon; Richard I Carp; Eun-Kyung Choi; Jin-Kyu Choi; Yong-Sun Kim
Pathological characterization of TgElk mice injected with brain homogenate from elk with chronic wasting disease.
Yun-Jung Lee; Richard I Carp; Eun-Kyoung Choi; Byung-Hoon Jeong; Yong-Sun Kim
Complete genome sequences of new xenotropic murine leukemia viruses from the senescence-accelerated mouse (SAM): molecular and phylogenetic analyses.

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2013: B-H Jeong; H-T Jin; Richard I Carp; Yong-Sun Kim
Bovine spongiform encephalopathy (BSE)-associated polymorphisms of the prion protein (PRNP) gene in Korean native cattle.
Animal genetics 2013;44(3):356.
2013: Yong-Chul Jeon; Richard I Carp; Eun-Kyung Choi; Jin-Kyu Choi; Yong-Sun Kim
Pathological characterization of TgElk mice injected with brain homogenate from elk with chronic wasting disease.
Journal of veterinary science 2013;14(1):21-6.
2013: Yun-Jung Lee; Richard I Carp; Eun-Kyoung Choi; Byung-Hoon Jeong; Yong-Sun Kim
Complete genome sequences of new xenotropic murine leukemia viruses from the senescence-accelerated mouse (SAM): molecular and phylogenetic analyses.
PloS one 2013;8(2):e55669.
2013: Byungki Jang; Yong-Sun Kim; Naoki Maruyama; Richard I Carp; Akihito Ishigami; Eun-Kyoung Choi
Peptidylarginine deiminase and protein citrullination in prion diseases: strong evidence of neurodegeneration.
Prion 2013;7(1):42-6.
2012: Byung-Hoon Jeong; Hyoung-Tae Jin; Richard I Carp; Eun-Kyoung Choi; Yong-Sun Kim
Lack of association between 14-3-3 beta gene (YWHAB) polymorphisms and sporadic Creutzfeldt-Jakob disease (CJD).
Molecular biology reports 2012;39(12):10647-53.
2012: Jae-Min Oh; Richard I Carp; Eun-Kyoung Choi; Yong-Sun Kim
Oxidative stress impairs autophagic flux in prion protein-deficient hippocampal cells.
Autophagy 2012;8(10):1448-61.
2012: Jisuk Yun; Yun-Jung Lee; Young-Jae Park; Richard I Carp; Eun-Kyoung Choi; Byung-Hoon Jeong; Hae-Jung Kim; Yong-Sun Kim
A polymorphism in the YWHAH gene encoding 14-3-3 eta that is not associated with sporadic Creutzfeldt-Jakob disease (CJD).
Molecular biology reports 2012;39(4):3619-25.
2011: Byung-Hoon Jeong; Kyung-Hee Lee; Yun-Jung Lee; J Yun; Y-J Park; Y-H Kim; Y-S Cho; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim
Genetic polymorphism in exon 2 of cathepsin D is not associated with vascular dementia.
Acta neurologica Scandinavica 2011;123(6):419-23.
2011: Jeong-Ho Park; Seok-Joo Park; Hae-Young Shin; Guang Y Wen; Richard I Carp; Yong-Chul Jeon; Jae-Kwang Jin; Boe-Hyun Kim; Yong-Sun Kim
Association of endothelial nitric oxide synthase and mitochondrial dysfunction in the hippocampus of scrapie-infected mice.
Hippocampus 2011;21(3):319-33.
2011: Byungki Jang; Hae-Young Shin; Jin-Kyu Choi; Du Phuong Thao Nguyen; Byung-Hoon Jeong; Akihito Ishigami; Naoki Maruyama; Richard I Carp; Yong-Sun Kim; Eun-Kyoung Choi
Subcellular localization of peptidylarginine deiminase 2 and citrullinated proteins in brains of scrapie-infected mice: nuclear localization of PAD2 and membrane fraction-enriched citrullinated proteins.
Journal of neuropathology and experimental neurology 2011;70(2):116-24.
2011: Jisuk Yun; Yun-Jung Lee; Richard I Carp; Eun-Kyoung Choi; Byung-Hoon Jeong; Hyoung-Tae Jin; Yong-Sun Kim
The first report of RPSA polymorphisms, also called 37/67 kDa LRP/LR gene, in sporadic Creutzfeldt-Jakob disease (CJD).
BMC medical genetics 2011;12():108.
2011: Byung-Hoon Jeong; Kyung-Hee Lee; Yun-Jung Lee; Jisuk Yun; Young-Jae Park; Han-Jeong Cho; Young-Hoon Kim; Young-Sook Cho; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim
Absence of association between two HECTD2 polymorphisms and sporadic Creutzfeldt-Jakob disease.
Dementia and geriatric cognitive disorders 2011;31(2):146-51.
2010: H P Lee; J K Choi; H Y Shin; Y C Jeon; Byung-Hoon Jeong; H G Lee; J I Kim; Eun-Kyoung Choi; Richard I Carp; Y S Kim
Altered expression of type 1 inositol 1,4,5-trisphosphate receptor in the Ngsk Prnp deficient mice.
Neuroscience 2010;167(3):799-808.
2010: Byungki Jang; Jae-Kwang Jin; Yong-Chul Jeon; Han Jeong Cho; Akihito Ishigami; Kyung-Chan Choi; Richard I Carp; Naoki Maruyama; Yong-Sun Kim; Eun-Kyoung Choi
Involvement of peptidylarginine deiminase-mediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease.
Acta neuropathologica 2010;119(2):199-210.
2010: Byung-Hoon Jeong; Yun-Jung Lee; Richard I Carp; Yong-Sun Kim
The prevalence of human endogenous retroviruses in cerebrospinal fluids from patients with sporadic Creutzfeldt-Jakob disease.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2010;47(2):136-42.
2009: Boe-Hyun Kim; Jun-Ho Song; Yong-Chul Jeon; Byung-Hoon Jeong; Sook-Kyung Yun; Hyoun Chan Cho; Richard I Carp; Yong-Sun Kim
Spontaneous immortalization of oligodendroglial cells derived from an SV40 T antigen-positive human glioblastoma multiforme.
Cancer letters 2009;283(2):212-21.
2009: Yeo-Jung Na; Jae-Kwang Jin; Yun-Jung Lee; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim
Increased neurogenesis in brains of scrapie-infected mice.
Neuroscience letters 2009;449(1):66-70.
2009: Byung-Hoon Jeong; Kyung-Hee Lee; Yun-Jung Lee; Jisuk Yun; Young-Jae Park; Yoonsang Bae; Young-Hoon Kim; Young-Sook Cho; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim
Genetic association of a cathepsin D polymorphism and sporadic Creutzfeldt-Jakob disease.
Dementia and geriatric cognitive disorders 2009;28(4):302-6.
2009: Byung-Hoon Jeong; Kyung-Hee Lee; Yun-Jung Lee; Yun Joong Kim; Eun-Kyoung Choi; Young-Hoon Kim; Young-Sook Cho; Richard I Carp; Yong-Sun Kim
Lack of association between PRNP 1368 polymorphism and Alzheimer's disease or vascular dementia.
BMC medical genetics 2009;10():32.
2008: Daryl Spinner; In Soo Cho; Seung Yong Park; Jae Il Kim; Harry C Meeker; Xuemin Ye; Giuseppe LaFauci; Daniel J Kerr; Michael J Flory; Bo Sook Kim; Regina B Kascsak; Thomas Wisniewski; William R Levis; Georgia B Schuller-Levis; Richard I Carp; Eunkyue Park; Richard J Kascsak
Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.
Journal of virology 2008;82(21):10701-8.
2008: Seok-Joo Park; Nam-Ho Kim; Byung-Hoon Jeong; Jae-Kwang Jin; Jin-Kyu Choi; Young-Jae Park; Jae-Il Kim; Richard I Carp; Yong-Sun Kim
The effect of Fenton reaction on protease-resistant prion protein (PrPSc) degradation and scrapie infectivity.
Brain research 2008;1238():172-80.
2008: Byungki Jang; Eunah Kim; Jin-Kyu Choi; Jae-Kwang Jin; Jae-Il Kim; Akihito Ishigami; Naoki Maruyama; Richard I Carp; Yong-Sun Kim; Eun-Kyoung Choi
Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesis.
The American journal of pathology 2008;173(4):1129-42.
2008: Jae-Min Oh; Hae-Young Shin; Seok-Joo Park; Boe-Hyun Kim; Jin-Kyu Choi; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim
The involvement of cellular prion protein in the autophagy pathway in neuronal cells.
Molecular and cellular neurosciences 2008;39(2):238-47.
2008: Byung-Hoon Jeong; K-H Lee; Y-J Lee; Y-H Kim; Y-S Cho; Richard I Carp; Y-S Kim
PRNP 1368 polymorphism is not associated with sporadic Creutzfeldt-Jakob disease in the Korean population.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2008;15(8):846-50.
2008: Boe-Hyun Kim; Harry C Meeker; Hae-Young Shin; Jae-Il Kim; Byung-Hoon Jeong; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim
Physiological properties of astroglial cell lines derived from mice with high (SAMP8) and low (SAMR1, ICR) levels of endogenous retrovirus.
Retrovirology 2008;5():104.
2007: Yeo-Jung Na; Jae-Kwang Jin; Jae-Il Kim; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim
JAK-STAT signaling pathway mediates astrogliosis in brains of scrapie-infected mice.
Journal of neurochemistry 2007;103(2):637-49.
2007: Boe-Hyun Kim; Yong-Chul Jun; Jae-Kwang Jin; Jae-Il Kim; Nam-Ho Kim; Elizabeth A Leibold; James Connor; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim
Alteration of iron regulatory proteins (IRP1 and IRP2) and ferritin in the brains of scrapie-infected mice.
Neuroscience letters 2007;422(3):158-63.
2007: Jae-Il Kim; Jae-Kwang Jin; Eun-Kyoung Choi; Daryl Spinner; Richard Rubenstein; Richard I Carp; Yong-Sun Kim
Increased expression and localization of cyclooxygenase-2 in astrocytes of scrapie-infected mice.
Journal of neuroimmunology 2007;187(1-2):74-82.
2007: Jae-Kwang Jin; Yeo-Jung Na; Joon-Ho Song; Hong-Gu Joo; Seungjoon Kim; Jae-Il Kim; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim; Taekyun Shin
Galectin-3 expression is correlated with abnormal prion protein accumulation in murine scrapie.
Neuroscience letters 2007;420(2):138-43.
2007: Byung-Hoon Jeong; K-H Lee; Y-E Jeong; K-A Hwang; Y-J Lee; Richard I Carp; Y-R Ju; Y-S Kim
Polymorphisms at codons 129 and 219 of the prion protein gene (PRNP) are not associated with sporadic Alzheimer's disease in the Korean population.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2007;14(6):621-6.
2007: Daryl Spinner; Regina B Kascsak; Giuseppe LaFauci; Harry C Meeker; Xuemin Ye; Michael J Flory; Jae Il Kim; Georgia B Schuller-Levis; William R Levis; Thomas Wisniewski; Richard I Carp; Richard J Kascsak
CpG oligodeoxynucleotide-enhanced humoral immune response and production of antibodies to prion protein PrPSc in mice immunized with 139A scrapie-associated fibrils.
Journal of leukocyte biology 2007;81(6):1374-85.
2007: Byung-Hoon Jeong; Hae-Ri Na; Jae-Chun Bae; Kyung-Hee Lee; Yun-Jung Lee; Nam-Ho Kim; Joon-Ho Song; Richard I Carp; Yong-Sun Kim
Absence of association between codon 129 and 219 polymorphisms of the prion protein gene and vascular dementia.
Dementia and geriatric cognitive disorders 2007;24(2):86-90.
2006: Yun-Jung Lee; Jae-Kwang Jin; Byung-Hoon Jeong; Richard I Carp; Yong-Sun Kim
Increased expression of glial cell line-derived neurotrophic factor (GDNF) in the brains of scrapie-infected mice.
Neuroscience letters 2006;410(3):178-82.
2006: Byung-Hoon Jeong; Yun-Jung Lee; Nam-Ho Kim; Richard I Carp; Yong-Sun Kim
Genotype distribution of the prion protein gene (PRNP) promoter polymorphisms in Korean cattle.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2006;49(12):1539-44.
2006: Giuseppe LaFauci; Richard I Carp; Harry C Meeker; Xuemin Ye; Jae I Kim; Michael Natelli; Marisol Cedeno; Robert B Petersen; Richard J Kascsak; Richard Rubenstein
Passage of chronic wasting disease prion into transgenic mice expressing Rocky Mountain elk (Cervus elaphus nelsoni) PrPC.
The Journal of general virology 2006;87(Pt 12):3773-80.
2006: Kyung-Hee Lee; Byung-Hoon Jeong; Jae-Kwang Jin; Harry C Meeker; Jae-Il Kim; Richard I Carp; Yong-Sun Kim
Scrapie infection activates the replication of ecotropic, xenotropic, and polytropic murine leukemia virus (MuLV) in brains and spinal cords of senescence-accelerated mice: implication of MuLV in progression of scrapie pathogenesis.
Biochemical and biophysical research communications 2006;349(1):122-30.
2006: Jin-Kyu Choi; Seok-Ju Park; Yong-Chul Jun; Jae-Min Oh; Byung-Hoon Jeong; Hyun-Pil Lee; Sue Nie Park; Richard I Carp; Yong-Sun Kim
Generation of monoclonal antibody recognized by the GXXXG motif (glycine zipper) of prion protein.
Hybridoma (2005) 2006;25(5):271-7.
2006: Andrzej W Vorbrodt; Danuta H Dobrogowska; Harry C Meeker; Richard I Carp
Quantitative immunogold study of increased expression of metallothionein-I/II in the brain perivascular areas of diabetic scrapie-infected mice.
Journal of molecular histology 2006;37(3-4):143-51.
2006: Joanna Pankiewicz; Frances Prelli; Man-Sun Sy; Richard J Kascsak; Regina B Kascsak; Daryl Spinner; Richard I Carp; Harry C Meeker; Martin Sadowski; Thomas Wisniewski
Clearance and prevention of prion infection in cell culture by anti-PrP antibodies.
The European journal of neuroscience 2006;23(10):2635-47.
2006: Samuel Sowemimo-Coker; S Pesci; F Andrade; A Kim; Regina B Kascsak; Richard J Kascsak; C Meeker; Richard I Carp
Pall leukotrap affinity prion-reduction filter removes exogenous infectious prions and endogenous infectivity from red cell concentrates.
Vox sanguinis 2006;90(4):265-75.
2006: Andrzej W Vorbrodt; Danuta H Dobrogowska; Michal Tarnawski; Harry C Meeker; Richard I Carp
Immunogold study of altered expression of some interendothelial junctional molecules in the brain blood microvessels of diabetic scrapie-infected mice.
Journal of molecular histology 2006;37(1-2):27-35.
2005: Samuel Sowemimo-Coker; Richard J Kascsak; Anzi Kim; Fabiola Andrade; Susan Pesci; Richard Kascsak; Clifford Meeker; Richard I Carp; Paul Brown
Removal of exogenous (spiked) and endogenous prion infectivity from red cells with a new prototype of leukoreduction filter.
Transfusion 2005;45(12):1839-44.
2005: Byung-Hoon Jeong; Kyung-Hee Lee; Nam-Ho Kim; Jae-Kwang Jin; Jae-Il Kim; Richard I Carp; Yong-Sun Kim
Association of sporadic Creutzfeldt-Jakob disease with homozygous genotypes at PRNP codons 129 and 219 in the Korean population.
Neurogenetics 2005;6(4):229-32.
2005: Hyun-Pil Lee; Yong-Cheol Jun; Jin-Kyu Choi; Jae-Il Kim; Richard I Carp; Yong-Sun Kim
Activation of mitogen-activated protein kinases in hamster brains infected with 263K scrapie agent.
Journal of neurochemistry 2005;95(2):584-93.
2005: Byung-Hoon Jeong; Nam-Ho Kim; Eun-Kyoung Choi; Chaeyoung Lee; Young-Han Song; Jae-Il Kim; Richard I Carp; Yong-Sun Kim
Polymorphism at 3' UTR +28 of the prion-like protein gene is associated with sporadic Creutzfeldt-Jakob disease.
European journal of human genetics : EJHG 2005;13(9):1094-7.
2005: Byung-Hoon Jeong; Hyun-Joo Sohn; Jong-O Lee; Nam-Ho Kim; Jae-Il Kim; Se-Young Lee; In-Soo Cho; Yi-Seok Joo; Richard I Carp; Yong-Sun Kim
Polymorphisms of the prion protein gene (PRNP) in Hanwoo (Bos taurus coreanae) and Holstein cattle.
Genes & genetic systems 2005;80(4):303-8.
2005: Nam-Ho Kim; Jin-Kyu Choi; Byung-Hoon Jeong; Jae-Il Kim; Myung-Sang Kwon; Richard I Carp; Yong-Sun Kim
Effect of transition metals (Mn, Cu, Fe) and deoxycholic acid (DA) on the conversion of PrPC to PrPres.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(7):783-5.
2005: Jae-Kwang Jin; Jin-Kyu Choi; Wilma Wasco; Joseph Buxbaum; Piotr B Kozlowski; Richard I Carp; Yong-Sun Kim; Eun-Kyoung Choi
Expression of calsenilin in neurons and astrocytes in the Alzheimer's disease brain.
Neuroreport 2005;16(5):451-5.
2005: Boe-Hyun Kim; Jae-Il Kim; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim
A neuronal cell line that does not express either prion or doppel proteins.
Neuroreport 2005;16(5):425-9.
2005: Jae-Kwang Jin; Nam-Ho Kim; Do Sik Min; Jae-Il Kim; Jin-Kyu Choi; Byung-Hoon Jeong; Seung-Il Choi; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim
Increased expression of phospholipase D1 in the brains of scrapie-infected mice.
Journal of neurochemistry 2005;92(3):452-61.
2005: Harry C Meeker; Xuemin Ye; Richard I Carp
The mouse model for scrapie: inoculation, clinical scoring, and histopathological techniques.
Methods in molecular biology (Clifton, N.J.) 2005;299():309-23.
2005: Byung-Hoon Jeong; Nam-Ho Kim; Jae-Il Kim; Richard I Carp; Yong-Sun Kim
Polymorphisms at codons 56 and 174 of the prion-like protein gene (PRND) are not associated with sporadic Creutzfeldt-Jakob disease.
Journal of human genetics 2005;50(6):311-4.
2005: F Goñi; Elin Knudsen; Fernanda Schreiber; Henrieta Scholtzova; Joanna Pankiewicz; Richard I Carp; Harry C Meeker; Richard Rubenstein; David Brown; Man-Sun Sy; José A Chabalgoity; Einar Sigurdsson; Thomas Wisniewski
Mucosal vaccination delays or prevents prion infection via an oral route.
Neuroscience 2005;133(2):413-21.
2005: Hyun-Pil Lee; Yong-Cheol Jun; Jin-Kyu Choi; Jae-Il Kim; Richard I Carp; Yong-Sun Kim
The expression of RANTES and chemokine receptors in the brains of scrapie-infected mice.
Journal of neuroimmunology 2005;158(1-2):26-33.
2004: X Ye; Harry C Meeker; Piotr B Kozlowski; Jerzy Wegiel; Kuo-Chiang Wang; Humi Imaki; Richard I Carp
Pathological changes in the liver of a senescence accelerated mouse strain (SAMP8): a mouse model for the study of liver diseases.
Histology and histopathology 2004;19(4):1141-51.
2004: Jae-Kwang Jin; Byung-Hoon Jeong; Yeo-Jung Na; Yong-Sun Kim; Richard I Carp; Myung-Bok Wie; Changjong Moon; Taekyun Shin
Increased expression of the embryonic intermediate filament, nestin, in the brains of scrapie-infected mice.
Neuroscience letters 2004;367(2):254-8.
2004: Yeong-Gon Choi; Jae-Il Kim; Yong-Chul Jeon; Seok-Joo Park; Eun-Kyoung Choi; Richard Rubenstein; Richard J Kascsak; Richard I Carp; Yong-Sun Kim
Nonenzymatic glycation at the N terminus of pathogenic prion protein in transmissible spongiform encephalopathies.
The Journal of biological chemistry 2004;279(29):30402-9.
2004: Martin Sadowski; Joanna Pankiewicz; Henrieta Scholtzova; Julia Tsai; Yongsheng Li; Richard I Carp; Harry C Meeker; Pierluigi Gambetti; Manik L Debnath; Chester A Mathis; Li Shao; Wen-Biao Gan; William E Klunk; Thomas Wisniewski
Targeting prion amyloid deposits in vivo.
Journal of neuropathology and experimental neurology 2004;63(7):775-84.
2004: Xuemin Ye; Harry C Meeker; Piotr Kozlowski; Richard I Carp
The occurrence of vacuolation, and periodic acid-Schiff (PAS)-positive granules and plaques in the brains of C57BL/6J, AKR, senescence-prone (SAMP8) and senescence-resistant (SAMR1) mice infected with various scrapie strains.
Brain research 2004;995(2):158-66.
2004: Byung-Hoon Jeong; Jae-Hwan Nam; Yun-Jung Lee; Kyung-Hee Lee; Myoung Kuk Jang; Richard I Carp; Ho-Dong Lee; Young-Ran Ju; Sangmee Ahn Jo; Keun-Yong Park; Yong-Sun Kim
Polymorphisms of the prion protein gene (PRNP) in a Korean population.
Journal of human genetics 2004;49(6):319-24.
2003: Einar Sigurdsson; David Brown; Muhammad A Alim; Henrieta Scholtzova; Richard I Carp; Harry C Meeker; Frances Prelli; Blas Frangione; Thomas Wisniewski
Copper chelation delays the onset of prion disease.
The Journal of biological chemistry 2003;278(47):46199-202.
2003: Martin Sadowski; Cheuk Tang; Juan Gilberto S Aguinaldo; Richard I Carp; Harry C Meeker; Thomas Wisniewski
In vivo micro magnetic resonance imaging signal changes in scrapie infected mice.
Neuroscience letters 2003;345(1):1-4.
2003: Einar Sigurdsson; Man-Sun Sy; Ruliang Li; Henrieta Scholtzova; Richard J Kascsak; Regina Kascsak; Richard I Carp; Harry C Meeker; Blas Frangione; Thomas Wisniewski
Anti-prion antibodies for prophylaxis following prion exposure in mice.
Neuroscience letters 2003;336(3):185-7.
2002: Byung-Hoon Jeong; Jae-Kwang Jin; Eun-Kyoung Choi; Eun Young Lee; Harry C Meeker; Christine A Kozak; Richard I Carp; Yong Sun Kim
Analysis of the expression of endogenous murine leukemia viruses in the brains of senescence-accelerated mice (SAMP8) and the relationship between expression and brain histopathology.
Journal of neuropathology and experimental neurology 2002;61(11):1001-12.
2002: Xuemin Ye; Harry C Meeker; P Kozlowski; Richard I Carp
Increased c-Fos protein in the brains of scrapie-infected SAMP8, SAMR1, AKR and C57BL mice.
Neuropathology and applied neurobiology 2002;28(5):358-66.
2002: Einar Sigurdsson; David Brown; Maki Daniels; Richard J Kascsak; Regina Kascsak; Richard I Carp; Harry C Meeker; Blas Frangione; Thomas Wisniewski
Immunization delays the onset of prion disease in mice.
The American journal of pathology 2002;161(1):13-7.
2002: Xuemin Ye; Richard I Carp
Increase of acidic fibroblast growth factor in the brains of hamsters infected with either 263K or 139H strains of scrapie.
Journal of molecular neuroscience : MN 2002;18(3):179-88.
2002: Richard I Carp; Harry C Meeker; R Chung; C A Kozak; M Hosokawa; H Fujisawa
Murine leukemia virus in organs of senescence-prone and -resistant mouse strains.
Mechanisms of ageing and development 2002;123(6):575-84.
2001: X Ye; Richard I Carp; Larry C Schmued; Andrew C Scallet
Fluoro-Jade and silver methods: application to the neuropathology of scrapie, a transmissible spongiform encephalopathy.
Brain research. Brain research protocols 2001;8(2):104-12.
2001: Xuemin Ye; Harry C Meeker; Andrew C Scallet; Richard I Carp
Comparison of NADPH diaphorase activity in the brains of hamsters infected with scrapie strains 139H or 263K or with normal hamster brain homogenate.
Histology and histopathology 2001;16(4):997-1004.
2001: Andrzej W Vorbrodt; Danuta H Dobrogowska; M Tarnawski; Harry C Meeker; Richard I Carp
Quantitative immunogold study of glucose transporter (GLUT-1) in five brain regions of scrapie-infected mice showing obesity and reduced glucose tolerance.
Acta neuropathologica 2001;102(3):278-84.
2001: Pierre Aucouturier; Frederic Geissmann; Diane Damotte; G P Saborio; Harry C Meeker; Richard J Kascsak; R Kascsak; Richard I Carp; Thomas Wisniewski
Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie.
The Journal of clinical investigation 2001;108(5):703-8.
2001: Xuemin Ye; R Rountree; Andrew C Scallet; Harry C Meeker; Richard I Carp
Evaluation of neurodegeneration in scrapie-infected animals by selective methods that detect cellular degeneration.
Brain research 2001;910(1-2):175-8.
2001: Jae-Il Kim; Seung-Il Choi; Nam-Ho Kim; Jae-Kwang Jin; Eun-Kyoung Choi; Richard I Carp; Yeong Shik Kim
Oxidative stress and neurodegeneration in prion diseases.
Annals of the New York Academy of Sciences 2001;928():182-6.
2000: N H Kim; S J Park; Jae-Kwang Jin; M S Kwon; Eun-Kyoung Choi; Richard I Carp; Yeong Shik Kim
Increased ferric iron content and iron-induced oxidative stress in the brains of scrapie-infected mice.
Brain research 2000;884(1--2):98-103.
2000: Yeong-Gon Choi; Jae-Il Kim; H P Lee; Jae-Kwang Jin; Eun-Kyoung Choi; Richard I Carp; Yeong Shik Kim
Induction of heme oxygenase-1 in the brains of scrapie-infected mice.
Neuroscience letters 2000;289(3):173-6.
2000: Pierre Aucouturier; Richard I Carp; Claude Carnaud; Thomas Wisniewski
Prion diseases and the immune system.
Clinical immunology (Orlando, Fla.) 2000;96(2):79-85.
2000: S K Park; Seung-Il Choi; Jae-Kwang Jin; Eun-Kyoung Choi; Jae-Il Kim; Richard I Carp; Yeong Shik Kim
Differential expression of Bax and Bcl-2 in the brains of hamsters infected with 263K scrapie agent.
Neuroreport 2000;11(8):1677-82.
2000: Richard I Carp; Harry C Meeker; Richard Rubenstein; S Sigurdarson; M Papini; Richard J Kascsak; Piotr B Kozlowski; Henryk M Wisniewski
Characteristics of scrapie isolates derived from hay mites.
Journal of neurovirology 2000;6(2):137-44.
2000: Claudio Soto; R J Kascsak; GP Saborío; Pierre Aucouturier; Thomas Wisniewski; Frances Prelli; Richard J Kascsak; E Mendez; D A Harris; James Ironside; Fabrizio Tagliavini; Richard I Carp; Blas Frangione
Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides.
Lancet 2000;355(9199):192-7.
2000: Richard I Carp; Harry C Meeker; I Kozlowski; Eugene A Sersen
An endogenous retrovirus and exogenous scrapie in a mouse model of aging.
Trends in microbiology 2000;8(1):39-42.
1999: Jae-Il Kim; WK Ju; J H Choi; E Choi; Richard I Carp; Henryk M Wisniewski; Yeong Shik Kim
Expression of cytokine genes and increased nuclear factor-kappa B activity in the brains of scrapie-infected mice.
Brain research. Molecular brain research 1999;73(1-2):17-27.
1999: Jae-Kwang Jin; Jin-Kyu Choi; Hyoung-gon Lee; Yeong Shik Kim; Richard I Carp; Eun-Kyoung Choi
Increased expression of CaM kinase II alpha in the brains of scrapie-infected mice.
Neuroscience letters 1999;273(1):37-40.
1999: Andrzej W Vorbrodt; Danuta H Dobrogowska; Harry C Meeker; Richard I Carp
Immunogold study of regional differences in the distribution of glucose transporter (GLUT-1) in mouse brain associated with physiological and accelerated aging and scrapie infection.
Journal of neurocytology 1999;28(9):711-9.
1999: Hyoung-gon Lee; S J Park; Eun-Kyoung Choi; Richard I Carp; Y S Kim
Increased expression of prion protein is associated with changes in dopamine metabolism and MAO activity in PC12 cells.
Journal of molecular neuroscience : MN 1999;13(1-2):121-6.
1999: Richard Rubenstein; R J Kascsak; M Papini; Richard J Kascsak; Richard I Carp; Giuseppe LaFauci; Rob H Meloen; Jan P M Langeveld
Immune surveillance and antigen conformation determines humoral immune response to the prion protein immunogen.
Journal of neurovirology 1999;5(4):401-13.
1999: X Ye; Andrew C Scallet; Richard I Carp
Abnormal periodic acid-Schiff (PAS)-positive substance in the islets of Langerhans, pituitaries and adrenal glands of 139H scrapie-infected hamsters.
Histology and histopathology 1999;14(3):673-8.
1999: Richard I Carp; Harry C Meeker; V Caruso; Eugene A Sersen
Scrapie strain-specific interactions with endogenous murine leukaemia virus.
The Journal of general virology 1999;80 ( Pt 1)():5-10.
1998: X Ye; Andrew C Scallet; Richard J Kascsak; Richard I Carp
Astrocytosis and proliferating cell nuclear antigen expression in brains of scrapie-infected hamsters.
Journal of molecular neuroscience : MN 1998;11(3):253-63.
1998: X Ye; Andrew C Scallet; Richard J Kascsak; Richard I Carp
Astrocytosis and amyloid deposition in scrapie-infected hamsters.
Brain research 1998;809(2):277-87.
1998: Richard I Carp; Harry C Meeker; Eugene A Sersen; P Kozlowski
Analysis of the incubation periods, induction of obesity and histopathological changes in senescence-prone and senescence-resistant mice infected with various scrapie strains.
The Journal of general virology 1998;79 ( Pt 11)():2863-9.
1998: Seung-Il Choi; WK Ju; Eun-Kyoung Choi; J Kim; H Z Lea; Richard I Carp; Henryk M Wisniewski; Yeong Shik Kim
Mitochondrial dysfunction induced by oxidative stress in the brains of hamsters infected with the 263 K scrapie agent.
Acta neuropathologica 1998;96(3):279-86.
1998: WK Ju; K J Park; Eun-Kyoung Choi; J Kim; Richard I Carp; Henryk M Wisniewski; Yeong Shik Kim
Expression of inducible nitric oxide synthase in the brains of scrapie-infected mice.
Journal of neurovirology 1998;4(4):445-50.
1998: S W Yun; Eun-Kyoung Choi; WK Ju; M S Ahn; Richard I Carp; Henryk M Wisniewski; Yeong Shik Kim
Extensive degeneration of catecholaminergic neurons to scrapie agent 87V in the brains of IM mice.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1998;34(2-3):121-32.
1997: Harry C Meeker; Richard I Carp
Titers of murine leukemia virus are higher in brains of SAMP8 than SAMR1 mice.
Neurobiology of aging 1997;18(5):543-7.
1997: Andrzej W Vorbrodt; Danuta H Dobrogowska; M Tarnawski; Harry C Meeker; Richard I Carp
Immunocytochemical evaluation of blood-brain barrier to endogenous albumin in scrapie-infected mice.
Acta neuropathologica 1997;93(4):341-8.
1997: X Ye; Andrew C Scallet; Richard I Carp
The 139H scrapie agent produces hypothalamic neurotoxicity and pancreatic islet histopathology: electron microscopic studies.
Neurotoxicology 1997;18(2):533-45.
1997: Richard J Kascsak; R Fersko; D Pulgiano; Richard Rubenstein; Richard I Carp
Immunodiagnosis of prion disease.
Immunological investigations 1997;26(1-2):259-68.
1997: Richard I Carp; Harry C Meeker; Eugene A Sersen
Scrapie strains retain their distinctive characteristics following passages of homogenates from different brain regions and spleen.
The Journal of general virology 1997;78 ( Pt 1)():283-90.
1996: X Ye; Richard I Carp
Histopathological changes in the pituitary glands of female hamsters infected with the 139H strain of scrapie.
Journal of comparative pathology 1996;114(3):291-304.
1996: X Ye; Richard I Carp
Margination and diapedesis of inflammatory cells in the islets of Langerhans in hamsters infected with the 139H strain of scrapie.
Journal of comparative pathology 1996;114(2):149-63.
1996: X Ye; Richard I Carp
Histopathological changes in the islets of Langerhans in hamsters infected with the 139H strain of scrapie: semi-thin section study.
Histology and histopathology 1996;11(1):161-70.
1995: X Ye; Richard I Carp
The pathological changes in peripheral organs of scrapie-infected animals.
Histology and histopathology 1995;10(4):995-1021.
1994: Richard Rubenstein; D Hui; R Race; W Ju; C Scalici; M Papini; Richard J Kascsak; Richard I Carp
Replication of scrapie strains in vitro and their influence on neuronal functions.
Annals of the New York Academy of Sciences 1994;724():331-7.
1994: Richard I Carp; X Ye; Richard J Kascsak; Richard Rubenstein
The nature of the scrapie agent. Biological characteristics of scrapie in different scrapie strain-host combinations.
Annals of the New York Academy of Sciences 1994;724():221-34.
1994: Richard Rubenstein; H Deng; R Race; W Ju; C Scalici; M Papini; A Rubenstein; Richard J Kascsak; Richard I Carp
Scrapie strain infection in vitro induces changes in neuronal cells.
Molecular neurobiology 1994;8(2-3):129-38.
1994: Richard I Carp; Richard J Kascsak; Richard Rubenstein; P A Merz
The puzzle of PrPSc and infectivity--do the pieces fit?
Trends in neurosciences 1994;17(4):148-9.
1994: X Ye; Richard I Carp; Y Yu; R Kozielski; P Kozlowski
Hyperplasia and hypertrophy of B cells in the islets of Langerhans in hamsters infected with the 139H strain of scrapie.
Journal of comparative pathology 1994;110(2):169-83.
1994: X Ye; Richard I Carp; Richard J Kascsak
Histopathological changes in the islets of Langerhans in scrapie 139H-affected hamsters.
Journal of comparative pathology 1994;110(2):153-67.
1994: Richard I Carp; S M Callahan; B A Patrick; P D Mehta
Interaction of scrapie agent and cells of the lymphoreticular system.
Archives of virology 1994;136(3-4):255-68.
1994: X Ye; Richard I Carp; Y Yu; R Kozielski; P Kozlowski
Effect of infection with the 139H scrapie strain on the number, area and/or location of hypothalamic CRF- and VP-immunostained neurons.
Acta neuropathologica 1994;88(1):44-54.
1994: Richard Rubenstein; Richard I Carp; W Ju; C Scalici; M Papini; A Rubenstein; Richard J Kascsak
Concentration and distribution of infectivity and PrPSc following partial denaturation of a mouse-adapted and a hamster-adapted scrapie strain.
Archives of virology 1994;139(3-4):301-11.
1993: J F Diedrich; Richard I Carp; Ashley T Haase
Increased expression of heat shock protein, transferrin, and beta 2-microglobulin in astrocytes during scrapie.
Microbial pathogenesis 1993;15(1):1-6.
1993: Richard J Kascsak; M Tonna-DeMasi; R Fersko; Richard Rubenstein; Richard I Carp; J M Powers
The role of antibodies to PrP in the diagnosis of transmissible spongiform encephalopathies.
Developments in biological standardization 1993;80():141-51.
1993: Richard I Carp; S M Callahan; Y Yu; Eugene A Sersen
Analysis of host genetic control of scrapie-induced obesity.
Archives of virology 1993;133(1-2):1-9.
1993: P Casaccia-Bonnefil; Richard J Kascsak; R Fersko; S Callahan; Richard I Carp
Brain regional distribution of prion protein PrP27-30 in mice stereotaxically microinjected with different strains of scrapie.
The Journal of infectious diseases 1993;167(1):7-12.
1992: Richard Rubenstein; H Deng; R E Race; W Ju; C L Scalici; M C Papini; Richard J Kascsak; Richard I Carp
Demonstration of scrapie strain diversity in infected PC12 cells.
The Journal of general virology 1992;73 ( Pt 11)():3027-31.
1991: J F Diedrich; H Minnigan; Richard I Carp; J N Whitaker; R Race; W Frey; Ashley T Haase
Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes.
Journal of virology 1991;65(9):4759-68.
1991: Richard Rubenstein; P A Merz; Richard J Kascsak; C L Scalici; M C Papini; Richard I Carp; R H Kimberlin
Scrapie-infected spleens: analysis of infectivity, scrapie-associated fibrils, and protease-resistant proteins.
The Journal of infectious diseases 1991;164(1):29-35.
1991: Richard I Carp; S M Callahan
Variation in the characteristics of 10 mouse-passaged scrapie lines derived from five scrapie-positive sheep.
The Journal of general virology 1991;72 ( Pt 2)():293-8.
1991: J F Diedrich; P E Bendheim; Y S Kim; Richard I Carp; Ashley T Haase
Scrapie-associated prion protein accumulates in astrocytes during scrapie infection.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(2):375-9.
1991: Richard J Kascsak; Richard Rubenstein; Richard I Carp
Evidence for biological and structural diversity among scrapie strains.
Current topics in microbiology and immunology 1991;172():139-52.
1991: J Diedrich; Stephen Wietgrefe; A Haase; J Duguid; Richard I Carp
Identifying and mapping changes in gene expression involved in the neuropathology of scrapie and Alzheimer's disease.
Current topics in microbiology and immunology 1991;172():259-74.
1990: Richard Rubenstein; C L Scalici; M C Papini; S M Callahan; Richard I Carp
Further characterization of scrapie replication in PC12 cells.
The Journal of general virology 1990;71 ( Pt 4)():825-31.
1990: Richard I Carp; Y S Kim; S M Callahan
Pancreatic lesions and hypoglycemia-hyperinsulinemia in scrapie-injected hamsters.
The Journal of infectious diseases 1990;161(3):462-6.
1990: Y S Kim; Richard I Carp; S M Callahan; Henryk M Wisniewski
Pathogenesis and pathology of scrapie after stereotactic injection of strain 22L in intact and bisected cerebella.
Journal of neuropathology and experimental neurology 1990;49(2):114-21.
1990: Y S Kim; Richard I Carp; S M Callahan; M Natelli; Henryk M Wisniewski
Vacuolization, incubation period and survival time analyses in three mouse genotypes injected stereotactically in three brain regions with the 22L scrapie strain.
Journal of neuropathology and experimental neurology 1990;49(2):106-13.
1990: Y S Kim; Richard I Carp; S Callahan; Henryk M Wisniewski
Incubation periods and histopathological changes in mice injected stereotaxically in different brain areas with the 87V scrapie strain.
Acta neuropathologica 1990;80(4):388-92.
1989: Richard I Carp; Y S Kim; S M Callahan
Scrapie-induced alterations in glucose tolerance in mice.
The Journal of general virology 1989;70 ( Pt 4)():827-35.
1989: Richard I Carp; Richard J Kascsak; Henryk M Wisniewski; P A Merz; Richard Rubenstein; P Bendheim; D Bolton
The nature of the unconventional slow infection agents remains a puzzle.
Alzheimer disease and associated disorders 1989;3(1-2):79-99.
1989: Richard I Carp; Y S Kim; Richard J Kascsak; P A Merz; Richard Rubenstein
Classic genetics of scrapie.
Progress in clinical and biological research 1989;317():567-82.
1988: Y S Kim; Richard I Carp; S M Callahan; Henryk M Wisniewski
Adrenal involvement in scrapie-induced obesity.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1988;189(1):21-7.
1988: M R Quinn; Y S Kim; Albert S Lossinsky; Richard I Carp
Influence of stereotaxically injected scrapie on neurotransmitter systems of mouse cerebellum.
Brain research 1988;445(2):297-302.
1987: Richard J Kascsak; Richard Rubenstein; P A Merz; M Tonna-DeMasi; R Fersko; Richard I Carp; Henryk M Wisniewski; H Diringer
Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins.
Journal of virology 1987;61(12):3688-93.
1987: Richard Rubenstein; P A Merz; Richard J Kascsak; Richard I Carp; C L Scalici; C L Fama; Henryk M Wisniewski
Detection of scrapie-associated fibrils (SAF) and SAF proteins from scrapie-affected sheep.
The Journal of infectious diseases 1987;156(1):36-42.
1987: Richard I Carp; R C Moretz; M Natelli; A G Dickinson
Genetic control of scrapie: incubation period and plaque formation in I mice.
The Journal of general virology 1987;68 ( Pt 2)():401-7.
1987: Albert S Lossinsky; R C Moretz; Richard I Carp; Henryk M Wisniewski
Ultrastructural observations of spinal cord lesions and blood-brain barrier changes in scrapie-infected mice.
Acta neuropathologica 1987;73(1):43-52.
1987: P A Merz; Richard J Kascsak; Richard Rubenstein; Richard I Carp; Henryk M Wisniewski
Antisera to scrapie-associated fibril protein and prion protein decorate scrapie-associated fibrils.
Journal of virology 1987;61(1):42-9.
1986: Nikolaos K Robakis; P R Sawh; G C Wolfe; Richard Rubenstein; Richard I Carp; M A Innis
Isolation of a cDNA clone encoding the leader peptide of prion protein and expression of the homologous gene in various tissues.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(17):6377-81.
1986: Richard J Kascsak; Richard Rubenstein; P A Merz; Richard I Carp; Nikolaos K Robakis; Henryk M Wisniewski; H Diringer
Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains.
Journal of virology 1986;59(3):676-83.
1986: Richard Rubenstein; Richard J Kascsak; P A Merz; Henryk M Wisniewski; Richard I Carp; Khalid Iqbal
Paired helical filaments associated with Alzheimer disease are readily soluble structures.
Brain research 1986;372(1):80-8.
1986: Richard Rubenstein; Richard J Kascsak; P A Merz; M C Papini; Richard I Carp; Nikolaos K Robakis; Henryk M Wisniewski
Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations.
The Journal of general virology 1986;67 ( Pt 4)():671-81.
1986: R A Somerville; P A Merz; Richard I Carp
Partial copurification of scrapie-associated fibrils and scrapie infectivity.
Intervirology 1986;25(1):48-55.
1985: Richard J Kascsak; Richard Rubenstein; P A Merz; Richard I Carp; Henryk M Wisniewski; H Diringer
Biochemical differences among scrapie-associated fibrils support the biological diversity of scrapie agents.
The Journal of general virology 1985;66 ( Pt 8)():1715-22.
1985: Richard I Carp; P A Merz; Richard J Kascsak; G S Merz; Henryk M Wisniewski
Nature of the scrapie agent: current status of facts and hypotheses.
The Journal of general virology 1985;66 ( Pt 7)():1357-68.
1984: R A Somerville; P A Merz; Richard I Carp
The effects of detergents on the composition of postsynaptic densities.
Journal of neurochemistry 1984;43(1):184-91.
1984: Richard I Carp; S M Callahan; Eugene A Sersen; R C Moretz
Preclinical changes in weight of scrapie-infected mice as a function of scrapie agent-mouse strain combination.
Intervirology 1984;21(2):61-9.
1984: Henryk M Wisniewski; G S Merz; Richard I Carp
Senile dementia of the Alzheimer type: possibility of infectious etiology in genetically susceptible individuals.
Acta neurologica Scandinavica. Supplementum 1984;99():91-7.
1983: Henryk M Wisniewski; Albert S Lossinsky; R C Moretz; Andrzej W Vorbrodt; H Lassmann; Richard I Carp
Increased blood-brain barrier permeability in scrapie-infected mice.
Journal of neuropathology and experimental neurology 1983;42(6):615-26.
1982: P B Kozlowski; R C Moretz; Richard I Carp; Henryk M Wisniewski
Retinal damage in scrapie mice.
Acta neuropathologica 1982;56(1):9-12.