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Christopher Carpenter

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Abdelhafid Saci; Lewis C Cantley; Christopher L Carpenter
Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.
Xinnong Jiang; Robert A Borgesi; Nicole C McKnight; Ramneet Kaur; Christopher L Carpenter; Steven P Balk
Activation of nonreceptor tyrosine kinase Bmx/Etk mediated by phosphoinositide 3-kinase, epidermal growth factor receptor, and ErbB3 in prostate cancer cells.
Abdelhafid Saci; Christopher L Carpenter
RhoA GTPase regulates B cell receptor signaling.

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All Publications

2011: Abdelhafid Saci; Lewis C Cantley; Christopher L Carpenter
Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.
Molecular cell 2011;42(1):50-61.
2007: Xinnong Jiang; Robert A Borgesi; Nicole C McKnight; Ramneet Kaur; Christopher L Carpenter; Steven P Balk
Activation of nonreceptor tyrosine kinase Bmx/Etk mediated by phosphoinositide 3-kinase, epidermal growth factor receptor, and ErbB3 in prostate cancer cells.
The Journal of biological chemistry 2007;282(45):32689-98.
2005: Abdelhafid Saci; Christopher L Carpenter
RhoA GTPase regulates B cell receptor signaling.
Molecular cell 2005;17(2):205-14.
2004: James D Chang; Seth J Field; Lucia E Rameh; Christopher L Carpenter; Lewis C Cantley
Identification and characterization of a phosphoinositide phosphate kinase homolog.
The Journal of biological chemistry 2004;279(12):11672-9.
2003: Kan Saito; Kimberley F Tolias; Abdelhafid Saci; Henry B Koon; Lisa A Humphries; Andrew M Scharenberg; David J Rawlings; Jean-Pierre Kinet; Christopher L Carpenter
BTK regulates PtdIns-4,5-P2 synthesis: importance for calcium signaling and PI3K activity.
Immunity 2003;19(5):669-78.
2003: Hongbing Zhang; Gregor Cicchetti; Hiroaki Onda; Henry B Koon; Kirsten Asrican; Natalia Bajraszewski; Francisca Vazquez; Christopher L Carpenter; David J Kwiatkowski
Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR.
The Journal of clinical investigation 2003;112(8):1223-33.
2003: Kurt Barkalow; Hervé Falet; Joseph E Italiano; Andrew van Vugt; Christopher L Carpenter; Alan D Schreiber; John H Hartwig
Role for phosphoinositide 3-kinase in Fc gamma RIIA-induced platelet shape change.
American journal of physiology. Cell physiology 2003;285(4):C797-805.
2000: Matthew P Coghlan; M M Chou; Christopher L Carpenter
Atypical protein kinases Clambda and -zeta associate with the GTP-binding protein Cdc42 and mediate stress fiber loss.
Molecular and cellular biology 2000;20(8):2880-9.
2000: Kimberley F Tolias; John H Hartwig; H Ishihara; Y Shibasaki; Lewis C Cantley; Christopher L Carpenter
Type Ialpha phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly.
Current biology : CB 2000;10(3):153-6.
2000: Kimberley F Tolias; Christopher L Carpenter
In vitro interaction of phosphoinositide-4-phosphate 5-kinases with Rac.
Methods in enzymology 2000;325():190-200.
1999: Gerhard Behre; A J Whitmarsh; Matthew P Coghlan; T Hoang; Christopher L Carpenter; Dong-Er Zhang; R J Davis; Daniel G Tenen
c-Jun is a JNK-independent coactivator of the PU.1 transcription factor.
The Journal of biological chemistry 1999;274(8):4939-46.
1999: Christopher L Carpenter; Kimberley F Tolias; A Van Vugt; J Hartwig
Lipid kinases are novel effectors of the GTPase Rac1.
Advances in enzyme regulation 1999;39():299-312.
1998: S Hübner; A D Couvillon; Josef Käs; Vytas A Bankaitis; Rolands Vegners; Christopher L Carpenter; Paul A Janmey
Enhancement of phosphoinositide 3-kinase (PI 3-kinase) activity by membrane curvature and inositol-phospholipid-binding peptides.
European journal of biochemistry / FEBS 1998;258(2):846-53.
1998: Kimberley F Tolias; Lucia E Rameh; H Ishihara; Y Shibasaki; J Chen; G D Prestwich; Lewis C Cantley; Christopher L Carpenter
Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphate.
The Journal of biological chemistry 1998;273(29):18040-6.
1998: Kimberley F Tolias; A D Couvillon; Lewis C Cantley; Christopher L Carpenter
Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complex.
Molecular and cellular biology 1998;18(2):762-70.
1997: F Berditchevski; Kimberley F Tolias; K Wong; Christopher L Carpenter; Martin Helmer
A novel link between integrins, transmembrane-4 superfamily proteins (CD63 and CD81), and phosphatidylinositol 4-kinase.
The Journal of biological chemistry 1997;272(5):2595-8.
1997: Christopher L Carpenter; Kimberley F Tolias; A C Couvillon; John H Hartwig
Signal transduction pathways involving the small G proteins rac and Cdc42 and phosphoinositide kinases.
Advances in enzyme regulation 1997;37():377-90.
1996: David A Fruman; Lewis C Cantley; Christopher L Carpenter
Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85 alpha gene.
Genomics 1996;37(1):113-21.
1996: Christopher L Carpenter; Lewis C Cantley
Phosphoinositide 3-kinase and the regulation of cell growth.
Biochimica et biophysica acta 1996;1288(1):M11-6.
1996: R Kolluri; Kimberley F Tolias; Christopher L Carpenter; Fred S Rosen; Tomas Kirchhausen
Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5615-8.
1996: Christopher L Carpenter; Lewis C Cantley
Phosphoinositide kinases.
Current opinion in cell biology 1996;8(2):153-8.
1995: R Kapeller; A Toker; Lewis C Cantley; Christopher L Carpenter
Phosphoinositide 3-kinase binds constitutively to alpha/beta-tubulin and binds to gamma-tubulin in response to insulin.
The Journal of biological chemistry 1995;270(43):25985-91.
1995: John H Hartwig; G M Bokoch; Christopher L Carpenter; Paul A Janmey; L A Taylor; A Toker; Thomas P Stossel
Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets.
Cell 1995;82(4):643-53.
1995: Kimberley F Tolias; Lewis C Cantley; Christopher L Carpenter
Rho family GTPases bind to phosphoinositide kinases.
The Journal of biological chemistry 1995;270(30):17656-9.
1993: Christopher L Carpenter; K R Auger; M Chanudhuri; M Yoakim; Brian Schaffhausen; Steven E Shoelson; Lewis C Cantley
Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit.
The Journal of biological chemistry 1993;268(13):9478-83.
1993: Christopher L Carpenter; K R Auger; Brian Duckworth; W M Hou; Brian Schaffhausen; Lewis C Cantley
A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity.
Molecular and cellular biology 1993;13(3):1657-65.
1992: M Yoakim; W Hou; Y Liu; Christopher L Carpenter; R Kapeller; Brian Schaffhausen
Interactions of polyomavirus middle T with the SH2 domains of the pp85 subunit of phosphatidylinositol-3-kinase.
Journal of virology 1992;66(9):5485-91.
1992: Andrea Graziani; L E Ling; G Endemann; Christopher L Carpenter; Lewis C Cantley
Purification and characterization of human erythrocyte phosphatidylinositol 4-kinase. Phosphatidylinositol 4-kinase and phosphatidylinositol 3-monophosphate 4-kinase are distinct enzymes.
The Biochemical journal 1992;284 ( Pt 1)():39-45.
1992: K R Auger; Christopher L Carpenter; Steven E Shoelson; Helen Piwnica-Worms; Lewis C Cantley
Polyoma virus middle T antigen-pp60c-src complex associates with purified phosphatidylinositol 3-kinase in vitro.
The Journal of biological chemistry 1992;267(8):5408-15.
1992: Stephen Soltoff; Christopher L Carpenter; K R Auger; R Kapeller; Brian Schaffhausen; Lewis C Cantley
Phosphatidylinositol-3 kinase and growth regulation.
Cold Spring Harbor symposia on quantitative biology 1992;57():75-80.
1990: Christopher L Carpenter; Lewis C Cantley
Phosphoinositide kinases.
Biochemistry 1990;29(51):11147-56.
1990: Christopher L Carpenter; Brian Duckworth; K R Auger; B Cohen; Brian Schaffhausen; Lewis C Cantley
Purification and characterization of phosphoinositide 3-kinase from rat liver.
The Journal of biological chemistry 1990;265(32):19704-11.
1989: K R Auger; Christopher L Carpenter; Lewis C Cantley; Lyuba Varticovski
Phosphatidylinositol 3-kinase and its novel product, phosphatidylinositol 3-phosphate, are present in Saccharomyces cerevisiae.
The Journal of biological chemistry 1989;264(34):20181-4.