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Jeffrey Bethony

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Stefan M Geiger; Anne Jardim-Botelho; Weston Williams; Neal Alexander; David J Diemert; Jeffrey Bethony
Serum CCL11 (eotaxin-1) and CCL17 (TARC) are serological indicators of multiple helminth infections and are driven by Schistosoma mansoni infection in humans.
Banchob Sripa; Eimorn Mairiang; Jason Mulvenna; Michael J Smout; Jeffrey Bethony; Paul J Brindley; Thewarach Laha; Alex Loukas
The tumorigenic liver fluke Opisthorchis viverrini--multiple pathways to cancer.
Ponlapat Yonglitthipagon; Jeffrey Bethony; Vajarabhongsa Bhudhisawasdi; Yaovalux Chamgramol; Alex Loukas; Jason Mulvenna; Chawalit Pairojkul; Banchob Sripa
Prognostic significance of peroxiredoxin 1 and ezrin-radixin-moesin-binding phosphoprotein 50 in cholangiocarcinoma.

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2013: Stefan M Geiger; Anne Jardim-Botelho; Weston Williams; Neal Alexander; David J Diemert; Jeffrey Bethony
Serum CCL11 (eotaxin-1) and CCL17 (TARC) are serological indicators of multiple helminth infections and are driven by Schistosoma mansoni infection in humans.
Tropical medicine & international health : TM & IH 2013;18(6):750-60.
2012: Banchob Sripa; Eimorn Mairiang; Jason Mulvenna; Michael J Smout; Jeffrey Bethony; Paul J Brindley; Thewarach Laha; Alex Loukas
The tumorigenic liver fluke Opisthorchis viverrini--multiple pathways to cancer.
Trends in parasitology 2012;28(10):395-407.
2012: Ponlapat Yonglitthipagon; Jeffrey Bethony; Vajarabhongsa Bhudhisawasdi; Yaovalux Chamgramol; Alex Loukas; Jason Mulvenna; Chawalit Pairojkul; Banchob Sripa
Prognostic significance of peroxiredoxin 1 and ezrin-radixin-moesin-binding phosphoprotein 50 in cholangiocarcinoma.
Human pathology 2012;43(10):1719-30.
2012: Bin Zhan; Jeffrey Bethony; L M de Oliveira; David J Diemert; X Feng; P Gillespie; P J Hotez; D Jiang; K Jones; B Keegan; Helton C Santiago; S-H Xiao; J Xue; Maria Elena Bottazzi
Fusion of Na-ASP-2 with human immunoglobulin Fcγ abrogates histamine release from basophils sensitized with anti-Na-ASP-2 IgE.
Parasite immunology 2012;34(8-9):404-11.
2012: Mark S Pearson; Maria Victoria Periago; Leon Tribolet; Maria Adela Valerio; Maria Adela Valero; Cinzia Cantacessi; David J Diemert; Peter Hotez; Amar R Jariwala; Alex Loukas; Jeffrey Bethony
Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines.
The Journal of allergy and clinical immunology 2012;130(1):13-21.
2012: David J Diemert; Janaina Freire; Robert G Hamilton; Peter J Hotez; Amar Jariwala; Alex Loukas; Jason Mulvenna; Maria Victoria Periago; Antonio G Pinto; Helton Santiago; Leon Tribolet; Rodrigo Correa-Oliveira; Jeffrey Bethony
Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths.
The Journal of allergy and clinical immunology 2012;130(1):169-76.e6.
2012: Jason Mulvenna; Banchob Sripa; Ponlapat Yonglitthipagon; Paul J Brindley; Alex Loukas; Jeffrey Bethony
Banking on the future: biobanking for "omics" approaches to biomarker discovery for Opisthorchis-induced cholangiocarcinoma in Thailand.
Parasitology international 2012;61(1):173-7.
2012: Eimorn Mairiang; Paiboon Sithithaworn; Smarn Tesana; Bandit Thinkhamrop; Jeffrey Bethony; Paul J Brindley; Sasithorn Kaewkes; Thewarach Laha; Alex Loukas; Banchob Sripa
Ultrasonography assessment of hepatobiliary abnormalities in 3359 subjects with Opisthorchis viverrini infection in endemic areas of Thailand.
Parasitology international 2012;61(1):208-11.
2012: Banchob Sripa; Bandit Thinkhamrop; Ponlapat Yonglitthipagon; Vajarabhongsa Bhudhisawasdi; Paul J Brindley; Sasithorn Kaewkes; Thewarach Laha; Alex Loukas; Eimorn Mairiang; Jason Mulvenna; Maria Victoria Periago; Paiboon Sithithaworn; Jeffrey Bethony
Elevated plasma IL-6 associates with increased risk of advanced fibrosis and cholangiocarcinoma in individuals infected by Opisthorchis viverrini.
PLoS neglected tropical diseases 2012;6(5):e1654.
2012: Mark S Pearson; Darren A Pickering; Leon Tribolet; Henry J McSorley; Jeffrey Bethony; Annnette Dougall; Peter J Hotez; Alex Loukas
Enhanced protective efficacy of a chimeric form of the schistosomiasis vaccine antigen Sm-TSP-2.
PLoS neglected tropical diseases 2012;6(3):e1564.
2011: Sujit S Nair; Kazufumi Ohshiro; Suresh B Pakala; Maria V Periago; Banchob Sripa; Sutas Suttiprapa; Jeffrey Bethony; Anitha Bommana; Paul J Brindley; Peter J Hotez; Thewarach Laha; Amanda J Lyon; Rakesh Kumar
Inflammatory response to liver fluke Opisthorchis viverrini in mice depends on host master coregulator MTA1, a marker for parasite-induced cholangiocarcinoma in humans.
Hepatology (Baltimore, Md.) 2011;54(4):1388-97.
2011: Stefan Michael Geiger; Neal Douglas Edward Alexander; Simon Brooker; Rodrigo Correa-Oliveira; Bonnie Cundill; David J Diemert; Ricardo Toshio Fujiwara; Jeffrey Bethony
Necator americanus and helminth co-infections: further down-modulation of hookworm-specific type 1 immune responses.
PLoS neglected tropical diseases 2011;5(9):e1280.
2011: Bonnie Cundill; David J Diemert; Rachel L Pullan; Neal Alexander; Jeffrey Bethony; Simon Brooker
Rates and intensity of re-infection with human helminths after treatment and the influence of individual, household, and environmental factors in a Brazilian community.
Parasitology 2011;138(11):1406-16.
2011: Banchob Sripa; Jeffrey Bethony; Peter J Hotez; Sasithorn Kaewkes; Thewarach Laha; Alex Loukas; Eimorn Mairiang; Jason Mulvenna; Paiboon Sithithaworn; Paul J Brindley
Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos.
Acta tropica 2011;120 Suppl 1():S158-68.
2011: Sujit S Nair; Kazufumi Ohshiro; Suresh B Pakala; Maria V Periago; Gabriel Rinaldi; Sutas Suttiprapa; Jeffrey Bethony; Anitha Bommana; Paul J Brindley; Peter J Hotez; Brian Keegan; Amanda J Lyon; Rakesh Kumar
The metastasis-associated protein-1 gene encodes a host permissive factor for schistosomiasis, a leading global cause of inflammation and cancer.
Hepatology (Baltimore, Md.) 2011;54(1):285-95.
2011: Neal Alexander; Bonnie Cundill; Lorenzo Sabatelli; Jeffrey Bethony; David J Diemert; Peter Hotez; Peter G Smith; Laura C Rodrigues; Simon Brooker
Selection and quantification of infection endpoints for trials of vaccines against intestinal helminths.
Vaccine 2011;29(20):3686-94.
2011: Michael J Smout; Banchob Sripa; Thewarach Laha; Jason Mulvenna; Robin B Gasser; Neil D Young; Jeffrey Bethony; Paul J Brindley; Alex Loukas
Infection with the carcinogenic human liver fluke, Opisthorchis viverrini.
Molecular bioSystems 2011;7(5):1367-75.
2011: Stefan Michael Geiger; Cristiano Massara; Rodrigo Corrêa-Oliveira; Omar Dos Santos Carvalho; Paula Albuquerque Freitas; Ricardo Toshio Fujiwara; Jeffrey Bethony
Excretory-secretory products from hookworm l(3) and adult worms suppress proinflammatory cytokines in infected individuals.
Journal of parasitology research 2011;2011():512154.
2011: Jeffrey Bethony; Rhea N Cole; Xiaoti Guo; Shaden Kamhawi; Marshall W Lightowlers; Alex Loukas; William Petri; Steven Reed; Jesus G Valenzuela; Peter J Hotez
Vaccines to combat the neglected tropical diseases.
Immunological reviews 2011;239(1):237-70.
2010: Peter J Hotez; Jeffrey Bethony; David J Diemert; Mark Pearson; Alex Loukas
Developing vaccines to combat hookworm infection and intestinal schistosomiasis.
Nature reviews. Microbiology 2010;8(11):814-26.
2010: Rupert J Quinnell; Rachel L Pullan; Lutz Breitling; Stefan M Geiger; Bonnie Cundill; Rodrigo Correa-Oliveira; Simon Brooker; Jeffrey Bethony
Genetic and household determinants of predisposition to human hookworm infection in a Brazilian community.
The Journal of infectious diseases 2010;202(6):954-61.
2010: Mark S Pearson; Darren A Pickering; Leon Tribolet; Leanne Cooper; Jason Mulvenna; Luciana M Oliveira; Jeffrey Bethony; Peter J Hotez; Alex Loukas
Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis.
The Journal of infectious diseases 2010;201(10):1561-9.
2010: Bin Zhan; Samirah Perally; Peter M Brophy; Jian Xue; Gaddam Goud; Sen Liu; Vehid Deumic; Luciana M de Oliveira; Jeffrey Bethony; Maria Elena Bottazzi; Desheng Jiang; Portia Gillespie; Shu-Hua Xiao; Richi Gupta; Alex Loukas; Najju Ranjit; Sara Lustigman; Yelena Oksov; Peter Hotez
Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus.
Infection and immunity 2010;78(4):1552-63.
2010: Rachel L Pullan; Jeffrey Bethony; Stefan M Geiger; Rodrigo Correa-Oliveira; Simon Brooker; Rupert J Quinnell
Human helminth co-infection: no evidence of common genetic control of hookworm and Schistosoma mansoni infection intensity in a Brazilian community.
International journal for parasitology 2010;40(3):299-306.
2010: Maria Flávia Gazzinelli; Lucas Lobato; Leonardo Matoso; Renato Avila; Rita de Cassia Marques; Ami Shah Brown; Rodrigo Correa-Oliveira; Jeffrey Bethony; David J Diemert
Health education through analogies: preparation of a community for clinical trials of a vaccine against hookworm in an endemic area of Brazil.
PLoS neglected tropical diseases 2010;4(7):e749.
2009: G G L Cançado; R T Fujiwara; P A Freitas; R Correa-Oliveira; Jeffrey Bethony
Acute generalized exanthematous pustulosis induced by itraconazole: an immunological approach.
Clinical and experimental dermatology 2009;34(8):e709-11.
2009: Banchob Sripa; Eimorn Mairiang; Bandit Thinkhamrop; Thewarach Laha; Sasithorn Kaewkes; Paiboon Sithithaworn; Smarn Tessana; Alex Loukas; Paul J Brindley; Jeffrey Bethony
Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6.
Hepatology (Baltimore, Md.) 2009;50(4):1273-81.
2009: Mark S Pearson; Jeffrey Bethony; Darren A Pickering; Luciana M de Oliveira; Amar Jariwala; Helton Santiago; Aaron P Miles; Bin Zhan; Desheng Jiang; Najju Ranjit; Jason Mulvenna; Leon Tribolet; Jordan Plieskatt; Tracey Smith; Maria Elena Bottazzi; Kathryn Jones; Brian Keegan; Peter J Hotez; Alex Loukas
An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(9):3007-19.
2009: Ricardo T Fujiwara; Guilherme G L Cançado; Paula A Freitas; Helton C Santiago; Cristiano Lara Massara; Omar Dos Santos Carvalho; Rodrigo Corrêa-Oliveira; Stefan M Geiger; Jeffrey Bethony
Necator americanus infection: a possible cause of altered dendritic cell differentiation and eosinophil profile in chronically infected individuals.
PLoS neglected tropical diseases 2009;3(3):e399.
2008: Andréa Teixeira Carvalho; Ricardo T Fujiwara; Erik J Stemmy; Denise Olive; Jesse M Damsker; Alex Loukas; Rodrigo Corrêa-Oliveira; Stephanie L Constant; Jeffrey Bethony
Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil.
Infection and immunity 2008;76(12):5810-6.
2008: Stefan M Geiger; Ricardo T Fujiwara; Helton Santiago; Rodrigo Corrêa-Oliveira; Jeffrey Bethony
Early stage-specific immune responses in primary experimental human hookworm infection.
Microbes and infection / Institut Pasteur 2008;10(14-15):1524-35.
2008: Tegan A Don; Jeffrey Bethony; Alex Loukas
Saposin-like proteins are expressed in the gastrodermis of Schistosoma mansoni and are immunogenic in natural infections.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2008;12(6):e39-47.
2008: Jeffrey Bethony; Rupert J Quinnell
Genetic epidemiology of human schistosomiasis in Brazil.
Acta tropica 2008;108(2-3):166-74.
2008: Peter J Hotez; Jeffrey Bethony; Sergio Costa Oliveira; Paul J Brindley; Alex Loukas
Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis.
Expert review of vaccines 2008;7(6):745-52.
2008: Anne Jardim-Botelho; Sophia Raff; Renato de Avila Rodrigues; Heather J Hoffman; David Joseph Diemert; Rodrigo Corrêa-Oliveira; Jeffrey Bethony; Maria Flávia Gazzinelli
Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren.
Tropical medicine & international health : TM & IH 2008;13(8):994-1004.
2008: Rodolfo C Giunchetti; Alexandre Barbosa Reis; Denise da Silveira-Lemos; Olindo Martins-Filho; Rodrigo Corrêa-Oliveira; Jeffrey Bethony; André Macedo Vale; Josiane da Silva Quetz; Lilian Lacerda Bueno; João Carlos França Silva; Evaldo Nascimento; Wilson Mayrink; Ricardo Toshio Fujiwara
Antigenicity of a whole parasite vaccine as promising candidate against canine leishmaniasis.
Research in veterinary science 2008;85(1):106-12.
2008: Jeffrey Bethony; David J Diemert; Sergio Costa Oliveira; Alex Loukas
Can schistosomiasis really be consigned to history without a vaccine?
Vaccine 2008;26(27-28):3373-6.
2008: Jeffrey Bethony; Gary Simon; David J Diemert; David Parenti; Aimee Desrosiers; Suzanne Schuck; Ricardo T Fujiwara; Helton Santiago; Peter J Hotez
Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults.
Vaccine 2008;26(19):2408-17.
2008: Alex Loukas; Jeffrey Bethony
New drugs for an ancient parasite.
Nature medicine 2008;14(4):365-7.
2008: Peter J Hotez; Paul J Brindley; Jeffrey Bethony; Charles H King; Edward J Pearce; Julie Jacobson
Helminth infections: the great neglected tropical diseases.
The Journal of clinical investigation 2008;118(4):1311-21.
2008: David J Diemert; Jeffrey Bethony; Peter J Hotez
Hookworm vaccines.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;46(2):282-8.
2007: Neal Alexander; Jeffrey Bethony; Rodrigo Corrêa-Oliveira; Laura C Rodrigues; Peter Hotez; Simon Brooker
Repeatability of paired counts.
Statistics in medicine 2007;26(19):3566-77.
2007: Banchob Sripa; Sasithorn Kaewkes; Paiboon Sithithaworn; Eimorn Mairiang; Thewarach Laha; Michael J Smout; Chawalit Pairojkul; Vajarabhongsa Bhudhisawasdi; Smarn Tesana; Bandit Thinkamrop; Jeffrey Bethony; Alex Loukas; Paul J Brindley
Liver fluke induces cholangiocarcinoma.
PLoS medicine 2007;4(7):e201.
2007: Stefan M Geiger; Iramaya R Caldas; B E Mc Glone; A C Campi-Azevedo; L M De Oliveira; Simon Brooker; David J Diemert; Rodrigo Corrêa-Oliveira; Jeffrey Bethony
Stage-specific immune responses in human Necator americanus infection.
Parasite immunology 2007;29(7):347-58.
2007: David J Diemert; Jeffrey Bethony
Re: Clinical trials in tropical diseases: a politically incorrect view.
Tropical medicine & international health : TM & IH 2007;12(3):470-1.
2007: Ricardo T Fujiwara; Bin Zhan; Susana Mendez; Alex Loukas; Lilian L Bueno; Yan Wang; Jordan Plieskatt; Yelena Oksov; Sara Lustigman; Maria Elena Bottazzi; Peter Hotez; Jeffrey Bethony
Reduction of worm fecundity and canine host blood loss mediates protection against hookworm infection elicited by vaccination with recombinant Ac-16.
Clinical and vaccine immunology : CVI 2007;14(3):281-7.
2007: Simon Brooker; Anne Jardim-Botelho; Rupert J Quinnell; Stefan M Geiger; Iramaya R Caldas; Fiona Fleming; Peter J Hotez; Rodrigo Correa-Oliveira; Laura C Rodrigues; Jeffrey Bethony
Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2007;101(2):146-54.
2006: Alex Loukas; Jeffrey Bethony; Simon Brooker; Peter Hotez
Hookworm vaccines: past, present, and future.
The Lancet infectious diseases 2006;6(11):733-41.
2006: Andréa Gazzinelli; Allen Hightower; Philip T LoVerde; João Paulo Amaral Haddad; Wesley Rodrigues Pereira; Jeffrey Bethony; Rodrigo Correa-Oliveira; Bernt Lindtjorn
The spatial distribution of Schistosoma mansoni infection before and after chemotherapy in the Jequitinhonha Valley in Brazil.
Memórias do Instituto Oswaldo Cruz 2006;101 Suppl 1():63-71.
2006: Simon Brooker; Neal Alexander; Stefan M Geiger; Rana A Moyeed; Julian Stander; Fiona Fleming; Peter J Hotez; Rodrigo Correa-Oliveira; Jeffrey Bethony
Contrasting patterns in the small-scale heterogeneity of human helminth infections in urban and rural environments in Brazil.
International journal for parasitology 2006;36(10-11):1143-51.
2006: Ricardo T Fujiwara; Stefan M Geiger; Jeffrey Bethony; Susana Mendez
Comparative immunology of human and animal models of hookworm infection.
Parasite immunology 2006;28(7):285-93.
2006: Mai H Tran; Mark S Pearson; Jeffrey Bethony; Danielle J Smyth; Malcolm K Jones; Mary Duke; Tegan A Don; Donald P McManus; Rodrigo Correa-Oliveira; Alex Loukas
Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis.
Nature medicine 2006;12(7):835-40.
2006: Peter J Hotez; Jeffrey Bethony; Maria Elena Bottazzi; Simon Brooker; David J Diemert; Alex Loukas
New technologies for the control of human hookworm infection.
Trends in parasitology 2006;22(7):327-31.
2006: Jeffrey Bethony; Simon Brooker; Marco Albonico; Stefan M Geiger; Alex Loukas; David J Diemert; Peter J Hotez
Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm.
Lancet 2006;367(9521):1521-32.
2006: Ricardo T Fujiwara; Alex Loukas; Susana Mendez; Angela L Williamson; Lilian L Bueno; Yan Wang; Andre Samuel; Bin Zhan; Maria Elena Bottazzi; Peter J Hotez; Jeffrey Bethony
Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogs.
Vaccine 2006;24(4):501-9.
2006: Fiona Fleming; Simon Brooker; Stefan M Geiger; Iramaya R Caldas; Rodrigo Correa-Oliveira; Peter J Hotez; Jeffrey Bethony
Synergistic associations between hookworm and other helminth species in a rural community in Brazil.
Tropical medicine & international health : TM & IH 2006;11(1):56-64.
2005: Alex Loukas; Jeffrey Bethony; Susana Mendez; Ricardo T Fujiwara; Gaddam Goud; Najju Ranjit; Bin Zhan; Karen Jones; Maria Elena Bottazzi; Peter J Hotez
Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs.
PLoS medicine 2005;2(10):e295.
2005: Bin Zhan; Sen Liu; Samirah Perally; Jian Xue; Ricardo T Fujiwara; Peter Brophy; Shuhua Xiao; Yueyuan Liu; Jianjun Feng; Angela Williamson; Yan Wang; Lilian L Bueno; Susana Mendez; Gaddam Goud; Jeffrey Bethony; John M Hawdon; Alex Loukas; Karen Jones; Peter J Hotez
Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum.
Infection and immunity 2005;73(10):6903-11.
2005: Jeffrey Bethony; Alex Loukas; Michael J Smout; Simon Brooker; Susana Mendez; Jordan Plieskatt; Gaddam Goud; Maria Elena Bottazzi; Bin Zhan; Yan Wang; Angela Williamson; Sara Lustigman; Rodrigo Correa-Oliveira; Shuhua Xiao; Peter J Hotez
Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(12):1743-5.
2005: Gaddam Goud; Maria Elena Bottazzi; Bin Zhan; Susana Mendez; Vehid Deumic; Jordan Plieskatt; Sen Liu; Yan Wang; Lilian L Bueno; Ricardo T Fujiwara; Andre Samuel; So Yeong Ahn; Maneesha Solanki; Oluwatoyin A Asojo; Jin Wang; Jeffrey Bethony; Alex Loukas; Michael Roy; Peter J Hotez
Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials.
Vaccine 2005;23(39):4754-64.
2005: Ricardo Toshio Fujiwara; André Macedo Vale; João Carlos França da Silva; Roberto Teodoro da Costa; Josiane da Silva Quetz; Olindo Martins-Filho; Alexandre Barbosa Reis; Rodrigo Corrêa-Oliveira; George Luiz Lins Machado-Coelho; Lilian Lacerda Bueno; Jeffrey Bethony; Glen Frank; Evaldo Nascimento; Odair Genaro; Wilson Mayrink; Steven Reed; Antonio Campos-Neto
Immunogenicity in dogs of three recombinant antigens (TSA, LeIF and LmSTI1) potential vaccine candidates for canine visceral leishmaniasis.
Veterinary research 2005;36(5-6):827-38.
2005: Peter Hotez; Jeffrey Bethony; Simon Brooker; Marco Albonico
Eliminating neglected diseases in Africa.
Lancet 2005;365(9477):2089.
2005: Susana Mendez; Bin Zhan; Gaddam Goud; Kashinath Ghosh; Azra Dobardzic; Wenhui Wu; Sen Liu; Vehid Deumic; Reshad Dobardzic; Yueyuan Liu; Jeffrey Bethony; Peter J Hotez
Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum.
Vaccine 2005;23(24):3123-30.
2005: Ricardo T Fujiwara; Jeffrey Bethony; Lilian L Bueno; Yan Wang; So Yeong Ahn; Andre Samuel; Maria Elena Bottazzi; Peter Hotez; Susana Mendez
Immunogenicity of the hookworm Na-ASP-2 vaccine candidate: characterization of humoral and cellular responses after vaccination in the Sprague Dawley rat.
Human vaccines 2005;1(3):123-8.
2005: Peter J Hotez; Jeffrey Bethony; Maria Elena Bottazzi; Simon Brooker; Paulo Buss
Hookworm: "the great infection of mankind".
PLoS medicine 2005;2(3):e67.
2005: Alex Loukas; Stephanie L Constant; Jeffrey Bethony
Immunobiology of hookworm infection.
FEMS immunology and medical microbiology 2005;43(2):115-24.
2005: Peter J Hotez; Sonia Arora; Jeffrey Bethony; Maria Elena Bottazzi; Alex Loukas; Rodrigo Correa-Oliveira; Simon Brooker
Helminth infections of children: prospects for control.
Advances in experimental medicine and biology 2005;568():135-44.
2005: Telcia V B Magalhães; Giovanni Gazzinelli; Maria Carolina B Alvarez; F C Lima e Silva; Lúcia A O Fraga; Alda M S Silveira; Andréa Gazzinelli; Jeffrey Bethony; Philip T LoVerde; Iramaya R Caldas; Rodrigo Correa-Oliveira; Aluízio Prata
Comparative clinical and ultrasound study of egg-negative and egg-positive individuals from Schistosoma mansoni low morbidity endemic areas, and hospitalized patients with hepatosplenic disease.
Revista da Sociedade Brasileira de Medicina Tropical 2005;38(1):33-7.
2004: E Speziali; Jeffrey Bethony; Olindo Martins-Filho; Lúcia A O Fraga; D S Lemos; L J Souza; Rodrigo Correa-Oliveira; A M C Faria
Production of interferon-gamma by natural killer cells and aging in chronic human schistosomiasis.
Mediators of inflammation 2004;13(5-6):327-33.
2004: Rupert J Quinnell; Jeffrey Bethony; David I Pritchard
The immunoepidemiology of human hookworm infection.
Parasite immunology 2004;26(11-12):443-54.
2004: Alda M S Silveira; Giovanni Gazzinelli; Lúcia Fraga Alves-Oliveira; Jeffrey Bethony; Andréa Gazzinelli; Claudia Carvalho-Queiroz; Maria Carolina B Alvarez; Francisco C Lima-Silva; Aluízio Prata; Philip T LoVerde; Rodrigo Correa-Oliveira
Human schistosomiasis mansoni: intensity of infection differentially affects the production of interleukin-10, interferon-gamma and interleukin-13 by soluble egg antigen or adult worm antigen stimulated cultures.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2004;98(9):514-9.
2004: Peter J Hotez; Simon Brooker; Jeffrey Bethony; Maria Elena Bottazzi; Alex Loukas; Shuhua Xiao
Hookworm infection.
The New England journal of medicine 2004;351(8):799-807.
2004: George C-F Hsieh; Alex Loukas; Allison M Wahl; Monica Bhatia; Yan Wang; Angela L Williamson; Kylene W Kehn; Haruhiko Maruyama; Peter J Hotez; David Leitenberg; Jeffrey Bethony; Stephanie L Constant
A secreted protein from the human hookworm necator americanus binds selectively to NK cells and induces IFN-gamma production.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2699-704.
2004: Ricardo Portela; Jeffrey Bethony; Maria I Costa; Andréa Gazzinelli; R W A Vitor; Flavio M Hermeto; Rodrigo Correa-Oliveira; Ricardo T Gazzinelli
A multihousehold study reveals a positive correlation between age, severity of ocular toxoplasmosis, and levels of glycoinositolphospholipid-specific immunoglobulin A.
The Journal of infectious diseases 2004;190(1):175-83.
2004: Alex Loukas; Jeffrey Bethony; Angela L Williamson; Gaddam Goud; Susana Mendez; Bin Zhan; John M Hawdon; Maria Elena Bottazzi; Paul J Brindley; Peter J Hotez
Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms.
The Journal of infectious diseases 2004;189(10):1952-61.
2004: Stefan M Geiger; Cristiano Massara; Jeffrey Bethony; Peter T Soboslay; Rodrigo Corrêa-Oliveira
Cellular responses and cytokine production in post-treatment hookworm patients from an endemic area in Brazil.
Clinical and experimental immunology 2004;136(2):334-40.
2004: Jeffrey Bethony; Jeff T Williams; Simon Brooker; Andréa Gazzinelli; Maria Flávia Gazzinelli; Philip T LoVerde; Rodrigo Corrêa-Oliveira; Bernt Lindtjorn
Exposure to Schistosoma mansoni infection in a rural area in Brazil. Part III: household aggregation of water-contact behaviour.
Tropical medicine & international health : TM & IH 2004;9(3):381-9.
2004: Simon Brooker; Jeffrey Bethony; Peter J Hotez
Human hookworm infection in the 21st century.
Advances in parasitology 2004;58():197-288.
2003: Gifone Aguiar Rocha; Andreia Maria Camargos Rocha; Luciana Diniz Silva; Adriana Santos; Ana Carolina Dias Bocewicz; Renata de Magalhães Queiroz Rd; Jeffrey Bethony; Andréa Gazzinelli; Rodrigo Corrêa-Oliveira; Dulciene M M Queiroz
Transmission of Helicobacter pylori infection in families of preschool-aged children from Minas Gerais, Brazil.
Tropical medicine & international health : TM & IH 2003;8(11):987-91.
2003: Peter J Hotez; Bin Zhan; Jeffrey Bethony; Alex Loukas; Angela Williamson; Gaddam Goud; John M Hawdon; Azra Dobardzic; Reshad Dobardzic; Kashinath Ghosh; Maria Elena Bottazzi; Susana Mendez; Bernard C Zook; Yan Wang; Sen Liu; Idong Essiet-Gibson; Sophia Chung-Debose; Shuhua Xiao; David Knox; Michael M Meagher; Mehmet Inan; Rodrigo Correa-Oliveira; Paul Vilk; Herman R Shepherd; Walter Brandt; Philip K Russell
Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative.
International journal for parasitology 2003;33(11):1245-58.
2003: Peter J Hotez; James Ashcom; Bin Zhan; Jeffrey Bethony; Alex Loukas; John M Hawdon; Yang Wang; Qun Jin; Karen C Jones; Azra Dobardzic; Reshad Dobardzic; Janelle Bolden; Idong Essiet; Walter Brandt; Philip K Russell; Bernard C Zook; Brian Howard; Marco Chacon
Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae.
The Journal of parasitology 2003;89(4):853-5.
2002: Jeffrey Bethony; Jizhang Chen; Shaoxiong Lin; Shuhua Xiao; Bin Zhan; Shangwen Li; Haichou Xue; Fuying Xing; Debbie Humphries; Wang Yan; Grace Chen; Virginia Foster; John M Hawdon; Peter J Hotez
Emerging patterns of hookworm infection: influence of aging on the intensity of Necator infection in Hainan Province, People's Republic of China.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002;35(11):1336-44.
2002: Stefan M Geiger; Cristiano Massara; Jeffrey Bethony; Peter T Soboslay; Omar S Carvalho; Rodrigo Corrêa-Oliveira
Cellular responses and cytokine profiles in Ascaris lumbricoides and Trichuris trichiura infected patients.
Parasite immunology 2002;24(11-12):499-509.
2002: Jeffrey Bethony; Jeff T Williams; John C Blangero; Bernt Lindtjorn; Andréa Gazzinelli; B Soares-Filho; L Coelho; L Alves-Fraga; Sarah Williams-Blangero; Philip T LoVerde; Rodrigo Correa-Oliveira
Additive host genetic factors influence fecal egg excretion rates during Schistosoma mansoni infection in a rural area in Brazil.
The American journal of tropical medicine and hygiene 2002;67(4):336-43.
2002: Peter J Hotez; James Ashcom; Zhan Bin; Jeffrey Bethony; Angela Williamson; John M Hawdon; Feng Jianjun; Azra Dobardzic; Ivania Rizo; Janelle Bolden; Qun Jin; Wang Yan; Reshad Dobardzic; Sophia Chung-Debose; Melissa Crowell; Bennett Datu; Angela Delaney; Dilyan Dragonovski; Yang Jiang; Liu Yueyuan; Kashinath Ghosh; Alex Loukas; Walter Brandt; Philip K Russell; Bernard C Zook
Effect of vaccinations with recombinant fusion proteins on Ancylostoma caninum habitat selection in the canine intestine.
The Journal of parasitology 2002;88(4):684-90.
2002: Alda M S Silveira; Jeffrey Bethony; Andréa Gazzinelli; Bernt Lindtjorn; Lúcia A O Fraga; Maria Carolina B Alvares; Aluízio Prata; Henrique L Guerra; Philip T LoVerde; Rodrigo Correa-Oliveira; Giovanni Gazzinelli
High levels of IgG4 to Schistosoma mansoni egg antigens in individuals with periportal fibrosis.
The American journal of tropical medicine and hygiene 2002;66(5):542-9.
2001: Jeffrey Bethony; Jeff T Williams; Bernt Lindtjorn; John C Blangero; L Alves-Fraga; G Buck; A Michalek; Sarah Williams-Blangero; Philip T LoVerde; R Corréa-Oliveira; Andréa Gazzinelli
Exposure to Schistosoma mansoni infection in a rural area in Brazil. II: household risk factors.
Tropical medicine & international health : TM & IH 2001;6(2):136-45.
2001: Andréa Gazzinelli; Jeffrey Bethony; Lúcia A O Fraga; Philip T LoVerde; Rodrigo Correa-Oliveira; Bernt Lindtjorn
Exposure to Schistosoma mansoni infection in a rural area of Brazil. I: water contact.
Tropical medicine & international health : TM & IH 2001;6(2):126-35.
2001: Bernt Lindtjorn; C de Souza; Andréa Gazzinelli; B S Soares Filho; Jeffrey Bethony; K Page; C Grzywacz; F Lewis; Dennis J Minchella; Philip T LoVerde; Rodrigo Corrêa Oliveira
The distribution of Biomphalaria spp. in different habitats in relation to physical, biological, water contact and cognitive factors in a rural area in Minas Gerais, Brazil.
Memórias do Instituto Oswaldo Cruz 2001;96 Suppl():57-66.
2001: Jeffrey Bethony; Andréa Gazzinelli; A Lopes; Wesley Rodrigues Pereira; Lúcia Fraga Alves-Oliveira; S Willams-Blangero; John C Blangero; Philip T LoVerde; Rodrigo Corrêa-Oliveira
Genetic epidemiology of fecal egg excretion during Schistosoma mansoni infection in an endemic area in Minas Gerais, Brazil.
Memórias do Instituto Oswaldo Cruz 2001;96 Suppl():49-55.
1999: Jeffrey Bethony; Alda M S Silveira; Lúcia Fraga Alves-Oliveira; A Thakur; Giovanni Gazzinelli; Rodrigo Correa-Oliveira; Philip T LoVerde
Familial resemblance in humoral immune response to defined and crude Schistosoma mansoni antigens in an endemic area in Brazil.
The Journal of infectious diseases 1999;180(5):1665-73.
1997: Peter J Hotez; Kashinath Ghosh; John M Hawdon; Sukanya Narasimhan; B Jones; Jeffrey Bethony
Vaccines for hookworm infection.
The Pediatric infectious disease journal 1997;16(10):935-40.