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Deborah Carper

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

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Rats
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Reverse Transcriptase Polymerase Chain Reaction

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Publications

TOP 3
Kutty R Krishnan; Chen Shanyi; Samuel William; Vijayasarathy Camasamudram; Duncan Todd; Tsai Jen-Yue; Fariss Robert N; Carper Deborah; Jaworski Cynthia; Wiggert Barbara
Cell density-dependent nuclear/cytoplasmic localization of NORPEG (RAI14) protein.
Darmanin Connie; Iwata Takeshi; Carper Deborah A; El-Kabbani Ossama
Discovery of potential sorbitol dehydrogenase inhibitors from virtual screening.
John-Aryankalayil Molykutty; Dushku Nicholas; Jaworski Cynthia J; Cox Constance A; Schultz Gregory; Smith Janine A; Ramsey Keri E; Stephan Dietrich A; Freedman Kenn A; Reid Ted W; Carper Deborah A
Microarray and protein analysis of human pterygium.

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All Publications

2006: Kutty R Krishnan; Chen Shanyi; Samuel William; Vijayasarathy Camasamudram; Duncan Todd; Tsai Jen-Yue; Fariss Robert N; Carper Deborah; Jaworski Cynthia; Wiggert Barbara
Cell density-dependent nuclear/cytoplasmic localization of NORPEG (RAI14) protein.
Biochemical and biophysical research communications 2006;345(4):1333-41.
2006: Darmanin Connie; Iwata Takeshi; Carper Deborah A; El-Kabbani Ossama
Discovery of potential sorbitol dehydrogenase inhibitors from virtual screening.
Medicinal chemistry (Shariqah (United Arab Emirates)) 2006;2(3):239-42.
2006: John-Aryankalayil Molykutty; Dushku Nicholas; Jaworski Cynthia J; Cox Constance A; Schultz Gregory; Smith Janine A; Ramsey Keri E; Stephan Dietrich A; Freedman Kenn A; Reid Ted W; Carper Deborah A
Microarray and protein analysis of human pterygium.
Molecular vision 2006;12():55-64.
2004: John Molykutty; Jaworski Cynthia; Chen Zhengguang; Subramanian Saradha; Ma Wanchao; Sun Fang; Li Dayu; Spector Abraham; Carper Deborah
Matrix metalloproteinases are down-regulated in rat lenses exposed to oxidative stress.
Experimental eye research 2004;79(6):839-46.
2004: Takada Yuichiro; Fariss Robert N; Tanikawa Atsuhiro; Zeng Yong; Carper Deborah; Bush Ronald; Sieving Paul A
A retinal neuronal developmental wave of retinoschisin expression begins in ganglion cells during layer formation.
Investigative ophthalmology & visual science 2004;45(9):3302-12.
2004: Ebong Samuel; Yu Cheng-Rong; Carper Deborah A; Chepelinsky Ana B; Egwuagu Charles E
Activation of STAT signaling pathways and induction of suppressors of cytokine signaling (SOCS) proteins in mammalian lens by growth factors.
Investigative ophthalmology & visual science 2004;45(3):872-8.
2004: Chen Zhengguang; John Molykutty; Subramanian Saradha; Chen Hong; Carper Deborah
17Beta-estradiol confers a protective effect against transforming growth factor-beta2-induced cataracts in female but not male lenses.
Experimental eye research 2004;78(1):67-74.
2003: Darmanin Connie; Iwata Takeshi; Carper Deborah A; Sparrow Lindsay G; Chung Roland P T; El-Kabbani Ossama
Expression, purification and preliminary crystallographic analysis of human sorbitol dehydrogenase.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 3):558-60.
2001: Carper D; John M; Chen Z; Subramanian S; Wang R; Ma W; Spector A
Gene expression analysis of an H(2)O(2)-resistant lens epithelial cell line.
Free radical biology & medicine 2001;31(1):90-7.
2000: Lichtstein D; McGowan M H; Russell P; Carper D A
Digitalis and digitalislike compounds down-regulate gene expression of the intracellular signaling protein 14-3-3 in rat lens.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23 Suppl():S51-3.
2000: Singh S B; Malamas M S; Hohman T C; Nilakantan R; Carper D A; Kitchen D
Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants.
Journal of medicinal chemistry 2000;43(6):1062-70.
2000: Sun J K; Iwata T; Zigler J S; Carper D A
Differential gene expression in male and female rat lenses undergoing cataract induction by transforming growth factor-beta (TGF-beta).
Experimental eye research 2000;70(2):169-81.
1999: El-Kabbani O; Old S E; Ginell S L; Carper D A
Aldose and aldehyde reductases: structure-function studies on the coenzyme and inhibitor-binding sites.
Molecular vision 1999;5():20.
1999: McGowan M H; Russell P; Carper D A; Lichtstein D
Na+, K+-ATPase inhibitors down-regulate gene expression of the intracellular signaling protein 14-3-3 in rat lens.
The Journal of pharmacology and experimental therapeutics 1999;289(3):1559-63.
1999: Wang Y; He H; Zigler J S; Iwata T; Ibaraki N; Reddy V N; Carper D
bFGF suppresses serum-deprivation-induced apoptosis in a human lens epithelial cell line.
Experimental cell research 1999;249(1):123-30.
1999: Iwata T; Sato S; Jimenez J; McGowan M; Moroni M; Dey A; Ibaraki N; Reddy V N; Carper D
Osmotic response element is required for the induction of aldose reductase by tumor necrosis factor-alpha.
The Journal of biological chemistry 1999;274(12):7993-8001.
1999: Carper D A; Sun J K; Iwata T; Zigler J S; Ibaraki N; Lin L R; Reddy V
Oxidative stress induces differential gene expression in a human lens epithelial cell line.
Investigative ophthalmology & visual science 1999;40(2):400-6.
1998: Hohman T C; El-Kabbani O; Malamas M S; Lai K; Putilina T; McGowan M H; Wane Y Q; Carper D A
Probing the inhibitor-binding site of aldose reductase with site-directed mutagenesis.
European journal of biochemistry / FEBS 1998;256(2):310-6.
1998: McGowan M H; Iwata T; Carper D A
Characterization of the mouse aldose reductase gene and promoter in a lens epithelial cell line.
Molecular vision 1998;4():2.
1997: Iwata T; Minucci S; McGowan M; Carper D
Identification of a novel cis-element required for the constitutive activity and osmotic response of the rat aldose reductase promoter.
The Journal of biological chemistry 1997;272(51):32500-6.
1997: el-Kabbani O; Carper D A; McGowan M H; Devedjiev Y; Rees-Milton K J; Flynn T G
Studies on the inhibitor-binding site of porcine aldehyde reductase: crystal structure of the holoenzyme-inhibitor ternary complex.
Proteins 1997;29(2):186-92.
1997: Iwata T; Minucci S; McGowan M; Carper D
Gene regulation of aldose reductase under osmotic stress.
Advances in experimental medicine and biology 1997;414():507-14.
1997: Sato S; Sugiyama K; Carper D
Aldose reductase as dihydrodiol dehydrogenase. Naphthoquinone formation by rat lens aldose reductase.
Advances in experimental medicine and biology 1997;414():499-505.
1995: Iwata T; Popescu N C; Zimonjic D B; Karlsson C; Höög J O; Vaca G; Rodriguez I R; Carper D
Structural organization of the human sorbitol dehydrogenase gene (SORD).
Genomics 1995;26(1):55-62.
1995: Old S E; Carper D A; Hohman T C
Na,K-ATPase response to osmotic stress in primary dog lens epithelial cells.
Investigative ophthalmology & visual science 1995;36(1):88-94.
1995: Carper D A; Hohman T C; Old S E
Residues affecting the catalysis and inhibition of rat lens aldose reductase.
Biochimica et biophysica acta 1995;1246(1):67-73.
1995: Iwata T; Carper D
Human sorbitol dehydrogenase gene. cDNA sequence and expression.
Advances in experimental medicine and biology 1995;372():373-81.
1995: Sato S; Old S; Carper D; Kador P F
Purification and characterization of recombinant human placental and rat lens aldose reductases expressed in Escherichia coli.
Advances in experimental medicine and biology 1995;372():259-68.
1993: Lin L R; Carper D; Yokoyama T; Reddy V N
The effect of hypertonicity on aldose reductase, alpha B-crystallin, and organic osmolytes in the retinal pigment epithelium.
Investigative ophthalmology & visual science 1993;34(7):2352-9.
1992: Dasgupta S; Hohman T C; Carper D
Hypertonic stress induces alpha B-crystallin expression.
Experimental eye research 1992;54(3):461-70.
1991: Graham C; Szpirer C; Levan G; Carper D
Characterization of the aldose reductase-encoding gene family in rat.
Gene 1991;107(2):259-67.
1991: Carper D; Sato S; Old S; Chung S; Kador P F
In vitro expression of human placental aldose reductase in Escherichia coli.
Advances in experimental medicine and biology 1991;284():129-38.
1991: Hohman T C; Carper D; Dasgupta S; Kaneko M
Osmotic stress induces aldose reductase in glomerular endothelial cells.
Advances in experimental medicine and biology 1991;284():139-52.
1990: Old S E; Sato S; Kador P F; Carper D A
In vitro expression of rat lens aldose reductase in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):4942-5.
1990: Carper D; Kaneko M; Stark H; Hohman T
Increase in aldose reductase mRNA in dog lens epithelial cells under hypertonic conditions.
Experimental eye research 1990;50(6):743-9.
1990: Kaneko M; Carper D; Nishimura C; Millen J; Bock M; Hohman T C
Induction of aldose reductase expression in rat kidney mesangial cells and Chinese hamster ovary cells under hypertonic conditions.
Experimental cell research 1990;188(1):135-40.
1989: Carper D A; Wistow G; Nishimura C; Graham C; Watanabe K; Fujii Y; Hayashi H; Hayaishi O
A superfamily of NADPH-dependent reductases in eukaryotes and prokaryotes.
Experimental eye research 1989;49(3):377-88.
1989: Nishimura C; Wistow G; Carper D
Rat lens aldose reductase: characterization of its primary structure, mRNA, and gene complexity.
Progress in clinical and biological research 1989;290():211-20.
1988: Nakamura M; Russell P; Carper D A; Inana G; Kinoshita J H
Alteration of a developmentally regulated, heat-stable polypeptide in the lens of the Philly mouse. Implications for cataract formation.
The Journal of biological chemistry 1988;263(35):19218-21.
1988: Nishimura C; Graham C; Hohman T C; Nagata M; Robison W G; Carper D
Characterization of mRNA and genes for aldose reductase in rat.
Biochemical and biophysical research communications 1988;153(3):1051-9.

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Deborah Carper

Research Profile (preview)

Chemicals & Drugs

Anatomy

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Concepts & Ideas

Phenomena

Procedures

Genes & Molecular Sequences

Physiology

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