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Jon Burrows

Research Profile

Living Beings

Chemicals & Drugs

Physiology

Mutation

Anatomy

Disorders

Procedures

Xenograft Model Antitumor Assays

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Publications

TOP 3
James G Christensen; Jon Burrows; Ravi Salgia
c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention.
James G Christensen; Randall E Schreck; Jon Burrows; Poonam Kuruganti; Emily Chan; Phuong Le; Jeffrey Chen; Xueyan Wang; Lany Ruslim; Robert Blake; Kenneth E Lipson; John Ramphal; Steven Do; Jingrong J Cui; Julie M Cherrington; Dirk B Mendel
A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.
Jeffrey H Teckman; Jon Burrows; Tunda Hidvegi; B Schmidt; Pamela Hale; David H Perlmutter
The proteasome participates in degradation of mutant alpha 1-antitrypsin Z in the endoplasmic reticulum of hepatoma-derived hepatocytes.

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All Publications

2005: James G Christensen; Jon Burrows; Ravi Salgia
c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention.
Cancer letters 2005;225(1):1-26.
2003: James G Christensen; Randall E Schreck; Jon Burrows; Poonam Kuruganti; Emily Chan; Phuong Le; Jeffrey Chen; Xueyan Wang; Lany Ruslim; Robert Blake; Kenneth E Lipson; John Ramphal; Steven Do; Jingrong J Cui; Julie M Cherrington; Dirk B Mendel
A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.
Cancer research 2003;63(21):7345-55.
2001: Jeffrey H Teckman; Jon Burrows; Tunda Hidvegi; B Schmidt; Pamela Hale; David H Perlmutter
The proteasome participates in degradation of mutant alpha 1-antitrypsin Z in the endoplasmic reticulum of hepatoma-derived hepatocytes.
The Journal of biological chemistry 2001;276(48):44865-72.
2000: Jon Burrows; L K Willis; D H Perlmutter
Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(4):1796-801.

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