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Roger Davis

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Myoung Sook Han; Dae Young Jung; Jason K Kim; Saquib A Lakhani; Caroline Morel; Richard A Flavell; Roger J Davis
JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation.
Hira Lal Goel; Chung-Cheng Hsieh; Irwin Leav; Stephen Lyle; Helty Adisetiyo; Cheng Chang; Ilsa M Coleman; Roger J Davis; Peter S Nelson; Stephen R Plymate; Bryan Pursell; Pradip Roy-Burman; Robert L Vessella; Hualin Simon Xi; Arthur M Mercurio
VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer.
Roger J Davis
Cell biology. A scaffold switch to insulate.

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2013: Myoung Sook Han; Dae Young Jung; Jason K Kim; Saquib A Lakhani; Caroline Morel; Richard A Flavell; Roger J Davis
JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation.
Science (New York, N.Y.) 2013;339(6116):218-22.
2012: Hira Lal Goel; Chung-Cheng Hsieh; Irwin Leav; Stephen Lyle; Helty Adisetiyo; Cheng Chang; Ilsa M Coleman; Roger J Davis; Peter S Nelson; Stephen R Plymate; Bryan Pursell; Pradip Roy-Burman; Robert L Vessella; Hualin Simon Xi; Arthur M Mercurio
VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer.
Cancer discovery 2012;2(10):906-21.
2012: Roger J Davis
Cell biology. A scaffold switch to insulate.
Science (New York, N.Y.) 2012;337(6099):1178-9.
2012: Anette Hübner; Maria Karasarides; David J Mulholland; Charles L Sawyers; Claire L Standen; Cathy Tournier; Hong Wu; Tamera Barrett; Julie Cavanagh-Kyros; Hongbo Chi; Richard A Flavell; Dale L Greiner; Roger J Davis
JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(30):12046-51.
2012: Cristina Cellurale; Julie Cavanagh-Kyros; David S Garlick; Nomeda Girnius; Feng Jiang; Shaolei Lu; Arthur M Mercurio; Roger J Davis
Role of JNK in mammary gland development and breast cancer.
Cancer research 2012;72(2):472-81.
2011: Wendy A Neveu; Matthew J Wargo; Laurie A Whittaker; Jenna L Allard; Edgar Bernardo; Roger J Davis; Yoichiro Iwakura; Viswas Nagaleekar; Mercedes Rincon
Fungal allergen β-glucans trigger p38 mitogen-activated protein kinase-mediated IL-6 translation in lung epithelial cells.
American journal of respiratory cell and molecular biology 2011;45(6):1133-41.
2011: Shashi Kant; Benjamin G Neel; Wojciech Swat; Sheng Zhang; Zhong-Yin Zhang; Richard A Flavell; Roger J Davis
TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway.
Genes & development 2011;25(19):2069-78.
2011: Rajkumar Noubade; Mercedes Rincon; Guadalupe Sabio; Naresha Saligrama; Karen Spach; Anthony Spitzack; Roger J Davis; Roxana Del Rio; Dimitry N Krementsov; Viswas Nagaleekar; Tina Thornton; Cory Teuscher
Activation of p38 MAPK in CD4 T cells controls IL-17 production and autoimmune encephalomyelitis.
Blood 2011;118(12):3290-300.
2011: Viswas K Nagaleekar; Guadalupe Sabio; Idil Aktan; Alan Chant; Isaac W Howe; Tina M Thornton; Patrick J Benoit; Roger J Davis; Mercedes Rincon; Jonathan Boyson
Translational control of NKT cell cytokine production by p38 MAPK.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(7):4140-6.
2011: Cristina Cellurale; Guadalupe Sabio; Norman J Kennedy; Madhumita Das; Marissa Barlow; Peter Sandy; Tyler Jacks; Roger J Davis
Requirement of c-Jun NH(2)-terminal kinase for Ras-initiated tumor formation.
Molecular and cellular biology 2011;31(7):1565-76.
2011: Madhumita Das; David S Garlick; Dale L Greiner; Roger J Davis
The role of JNK in the development of hepatocellular carcinoma.
Genes & development 2011;25(6):634-45.
2011: Ping Xu; Madhumita Das; Judith Reilly; Roger J Davis
JNK regulates FoxO-dependent autophagy in neurons.
Genes & development 2011;25(4):310-22.
2010: F Donelson Smith; Lorene K Langeberg; Cristina Cellurale; Tony Pawson; Deborah K Morrison; Roger J Davis; John D Scott
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade.
Nature cell biology 2010;12(12):1242-9.
2010: Schahram Akbarian; Roger J Davis
Keep the 'phospho' on MAPK, be happy.
Nature medicine 2010;16(11):1187-8.
2010: Caroline Morel; Claire L Standen; Dae Young Jung; Susan Gray; Helena Ong; Richard A Flavell; Jason K Kim; Roger J Davis
Requirement of JIP1-mediated c-Jun N-terminal kinase activation for obesity-induced insulin resistance.
Molecular and cellular biology 2010;30(19):4616-25.
2010: Ping Xu; Roger J Davis
c-Jun NH2-terminal kinase is required for lineage-specific differentiation but not stem cell self-renewal.
Molecular and cellular biology 2010;30(6):1329-40.
2010: Guadalupe Sabio; Julie Cavanagh-Kyros; Tamera Barrett; Dae Young Jung; Hwi Jin Ko; Helena Ong; Caroline Morel; Alfonso Mora; Judith Reilly; Jason K Kim; Roger J Davis
Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1.
Genes & development 2010;24(3):256-64.
2010: Cristina Cellurale; Claire R Weston; Judith Reilly; David S Garlick; D Joseph Jerry; Hayla K Sluss; Roger J Davis
Role of JNK in a Trp53-dependent mouse model of breast cancer.
PloS one 2010;5(8):e12469.
2010: Guadalupe Sabio; Norman J Kennedy; Julie Cavanagh-Kyros; Dae Young Jung; Hwi Jin Ko; Helena Ong; Tamera Barrett; Jason K Kim; Roger J Davis
Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance.
Molecular and cellular biology 2010;30(1):106-15.
2010: Anette Hübner; Julie Cavanagh-Kyros; Mercedes Rincon; Richard A Flavell; Roger J Davis
Functional cooperation of the proapoptotic Bcl2 family proteins Bmf and Bim in vivo.
Molecular and cellular biology 2010;30(1):98-105.
2009: Guadalupe Sabio; Julie Cavanagh-Kyros; Hwi Jin Ko; Dae Young Jung; Susan Gray; John Y Jun; Tamera Barrett; Alfonso Mora; Jason K Kim; Roger J Davis
Prevention of steatosis by hepatic JNK1.
Cell metabolism 2009;10(6):491-8.
2009: Claire L Standen; Norman J Kennedy; Richard A Flavell; Roger J Davis
Signal transduction cross talk mediated by Jun N-terminal kinase-interacting protein and insulin receptor substrate scaffold protein complexes.
Molecular and cellular biology 2009;29(17):4831-40.
2009: Caroline Morel; Scott M Carlson; Forest M White; Roger J Davis
Mcl-1 integrates the opposing actions of signaling pathways that mediate survival and apoptosis.
Molecular and cellular biology 2009;29(14):3845-52.
2009: Mercedes Rincón; Roger J Davis
Regulation of the immune response by stress-activated protein kinases.
Immunological reviews 2009;228(1):212-24.
2009: Madhumita Das; Guadalupe Sabio; Feng Jiang; Mercedes Rincón; Richard A Flavell; Roger J Davis
Induction of hepatitis by JNK-mediated expression of TNF-alpha.
Cell 2009;136(2):249-60.
2008: Guadalupe Sabio; Madhumita Das; Alfonso Mora; Zhiyou Zhang; John Y Jun; Hwi Jin Ko; Tamera Barrett; Jason K Kim; Roger J Davis
A stress signaling pathway in adipose tissue regulates hepatic insulin resistance.
Science (New York, N.Y.) 2008;322(5907):1539-43.
2008: Thomas J Fitzgerald; Tao Wang; Hira Lal Goel; Jiayi Huang; Gary Stein; Jane Lian; Roger J Davis; Steven Doxsey; Kethandapatti C Balaji; Jesse N Aronowitz; Lucia R Languino
Prostate carcinoma and radiation therapy: therapeutic treatment resistance and strategies for targeted therapeutic intervention.
Expert review of anticancer therapy 2008;8(6):967-74.
2008: Anette Hübner; Tamera Barrett; Richard A Flavell; Roger J Davis
Multisite phosphorylation regulates Bim stability and apoptotic activity.
Molecular cell 2008;30(4):415-25.
2008: Tina M Thornton; Gustavo Pedraza-Alva; Bin Deng; C David Wood; Alexander Aronshtam; James L Clements; Guadalupe Sabio; Roger J Davis; Dwight Matthews; Bradley Doble; Mercedes Rincon
Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation.
Science (New York, N.Y.) 2008;320(5876):667-70.
2008: John F Alcorn; Amy S Guala; Jos van der Velden; Brian McElhinney; Charles G Irvin; Roger J Davis; Yvonne M W Janssen-Heininger
Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-beta1.
Journal of cell science 2008;121(Pt 7):1036-45.
2008: Elizabeth Keramaris; Vladimir A Ruzhynsky; Steven M Callaghan; Estelle Wong; Roger J Davis; Richard Flavell; ruth slack; David Park
Required roles of Bax and JNKs in central and peripheral nervous system death of retinoblastoma-deficient mice.
The Journal of biological chemistry 2008;283(1):405-15.
2008: Joao H F Pedra; Jochen Mattner; Jian Tao; Steven M Kerfoot; Roger J Davis; Richard A Flavell; Philip W Askenase; Zhinan Yin; Erol Fikrig
c-Jun NH2-terminal kinase 2 inhibits gamma interferon production during Anaplasma phagocytophilum infection.
Infection and immunity 2008;76(1):308-16.
2007: Madhumita Das; Feng Jiang; Hayla K Sluss; Chao Zhang; Kevan M Shokat; Richard A Flavell; Roger J Davis
Suppression of p53-dependent senescence by the JNK signal transduction pathway.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(40):15759-64.
2007: Norman J Kennedy; Gilles Martin; Anka G Ehrhardt; Julie Cavanagh-Kyros; Chia-Yi Kuan; Pasko Rakic; Richard A Flavell; Steven N Treistman; Roger J Davis
Requirement of JIP scaffold proteins for NMDA-mediated signal transduction.
Genes & development 2007;21(18):2336-46.
2007: Ashwini K Mishra; Laxman Dass Gangwani; Roger J Davis; David G Lambright
Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):13930-5.
2007: Anja Jaeschke; Roger J Davis
Metabolic stress signaling mediated by mixed-lineage kinases.
Molecular cell 2007;27(3):498-508.
2007: Jasmina J Allen; Manqing Li; Craig S Brinkworth; Jennifer L Paulson; Dan Wang; Anette Hübner; Wen-Hai Chou; Roger J Davis; Al L Burlingame; Robert O Messing; Carol D Katayama; Stephen M Hedrick; Kevan M Shokat
A semisynthetic epitope for kinase substrates.
Nature methods 2007;4(6):511-6.
2007: James E Clark; Richard A Flavell; Matthew E Faircloth; Roger J Davis; Richard J Heads; Michael S Marber
Post-infarction remodeling is independent of mitogen-activated protein kinase kinase 3 (MKK3).
Cardiovascular research 2007;74(3):466-70.
2007: Claire R Weston; Roger J Davis
The JNK signal transduction pathway.
Current opinion in cell biology 2007;19(2):142-9.
2007: Jian Tao; Yunfei Gao; Ming O Li; Weifeng He; Liang Chen; Bohdan Harvev; Roger J Davis; Richard A Flavell; Zhinan Yin
JNK2 negatively regulates CD8+ T cell effector function and anti-tumor immune response.
European journal of immunology 2007;37(3):818-29.
2007: Norman J Kennedy; Cristina Cellurale; Roger J Davis
A radical role for p38 MAPK in tumor initiation.
Cancer cell 2007;11(2):101-3.
2006: Anette Hübner; Anja Jaeschke; Roger J Davis
Oncogene addiction: role of signal attenuation.
Developmental cell 2006;11(6):752-4.
2006: Guanghong Liao; Qinghua Tao; Matt Kofron; Juei-Suei Chen; Aryn Schloemer; Roger J Davis; Jen-Chih Hsieh; Chris Wylie; Janet Heasman; Chia-Yi Kuan
Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16313-8.
2006: Irina Groisman; Maria Ivshina; Veronica Marin; Norman J Kennedy; Roger J Davis; Joel D Richter
Control of cellular senescence by CPEB.
Genes & development 2006;20(19):2701-12.
2006: Anja Jaeschke; Maria Karasarides; Juan-Jose Ventura; Anka Ehrhardt; Chao Zhang; Richard A Flavell; Kevan M Shokat; Roger J Davis
JNK2 is a positive regulator of the cJun transcription factor.
Molecular cell 2006;23(6):899-911.
2006: Elise H Tran; Yasu-Taka Azuma; Manchuan Chen; Claire Weston; Roger J Davis; Richard A Flavell
Inactivation of JNK1 enhances innate IL-10 production and dampens autoimmune inflammation in the brain.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(36):13451-6.
2006: Faisal Adhami; Guanghong Liao; Yury M Morozov; Aryn Schloemer; Vincent J Schmithorst; John N Lorenz; R Scott Dunn; Charles V Vorhees; MARSHA WILLS-KARP; Jay L Degen; Roger J Davis; Noboru Mizushima; Pasko Rakic; Bernard Dardzinski; Scott K Holland; Frank R Sharp; Chia-Yi Kuan
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy.
The American journal of pathology 2006;169(2):566-83.
2006: Mohamed Bellahcene; Sebastien Jacquet; Xue B Cao; Masaya Tanno; Robert S Haworth; Joanne Layland; Alamgir M N Kabir; Matthias Gaestel; Roger J Davis; Richard A Flavell; Ajay M Shah; Metin Avkiran; Michael S Marber
Activation of p38 mitogen-activated protein kinase contributes to the early cardiodepressant action of tumor necrosis factor.
Journal of the American College of Cardiology 2006;48(3):545-55.
2006: Hayla K Sluss; Roger J Davis
H2AX is a target of the JNK signaling pathway that is required for apoptotic DNA fragmentation.
Molecular cell 2006;23(2):152-3.
2006: Hideo Tachibana; Cinzia Perrino; Hideyuki Takaoka; Roger J Davis; Sathyamangla V Naga Prasad; Howard A Rockman
JNK1 is required to preserve cardiac function in the early response to pressure overload.
Biochemical and biophysical research communications 2006;343(4):1060-6.
2006: Beth Doran; Norberto Gherbesi; Gregory M Hendricks; Richard A Flavell; Roger J Davis; Laxman Dass Gangwani
Deficiency of the zinc finger protein ZPR1 causes neurodegeneration.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(19):7471-5.
2006: Juan-Jose Ventura; Anette Hübner; Chao Zhang; Richard A Flavell; Kevan M Shokat; Roger J Davis
Chemical genetic analysis of the time course of signal transduction by JNK.
Molecular cell 2006;21(5):701-10.
2005: Yunfei Gao; Jian Tao; Ming O Li; Dongqing Zhang; Hongbo Chi; Octavian Henegariu; Susan M Kaech; Roger J Davis; Richard A Flavell; Zhinan Yin
JNK1 is essential for CD8+ T cell-mediated tumor immune surveillance.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5783-9.
2005: Alamgir M N Kabir; Xuebin Cao; Diana A Gorog; Masaya Tanno; Rekha Bassi; Mohamed Bellahcene; Roy A Quinlan; Roger J Davis; Richard A Flavell; Michael J Shattock; Michael S Marber
Antimycin A induced cardioprotection is dependent on pre-ischemic p38-MAPK activation but independent of MKK3.
Journal of molecular and cellular cardiology 2005;39(4):709-17.
2005: Anja Jaeschke; Mercedes Rincón; Beth Doran; Judy Reilly; Donna Neuberg; Dale L Greiner; Leonard D Shultz; Aldo A Rossini; Richard A Flavell; Roger J Davis
Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(19):6931-5.
2005: Deborah Brancho; Juan-Jose Ventura; Anja Jaeschke; Beth Doran; Richard A Flavell; Roger J Davis
Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades.
Molecular and cellular biology 2005;25(9):3670-81.
2005: Laxman Dass Gangwani; Richard A Flavell; Roger J Davis
ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies.
Molecular and cellular biology 2005;25(7):2744-56.
2005: Nyaya Kelkar; Claire L Standen; Roger J Davis
Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways.
Molecular and cellular biology 2005;25(7):2733-43.
2005: Seung Wook Oh; Arnab Mukhopadhyay; Nenad Svrzikapa; Feng Jiang; Roger J Davis; Heidi A Tissenbaum
JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4494-9.
2005: Elizabeth Keramaris; Jacqueline L Vanderluit; Mohammad Bahadori; Kambiz Mousavi; Roger J Davis; Richard Flavell; ruth slack; David Park
c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation.
The Journal of biological chemistry 2005;280(2):1132-41.
2004: Juan-Jose Ventura; Patricia C Cogswell; Richard A Flavell; Albert S Baldwin; Roger J Davis
JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species.
Genes & development 2004;18(23):2905-15.
2004: Chia-Yi Kuan; Aryn Schloemer; Aigang Lu; Kevin A Burns; Wei-Lan Weng; Michael T Williams; Kenneth I Strauss; Charles V Vorhees; Richard A Flavell; Roger J Davis; Frank R Sharp; Pasko Rakic
Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(47):10763-72.
2004: Claire R Weston; Anthony Wong; J Perry Hall; Mary E P Goad; Richard A Flavell; Roger J Davis
The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(39):14114-9.
2004: Anja Jaeschke; Michael P Czech; Roger J Davis
An essential role of the JIP1 scaffold protein for JNK activation in adipose tissue.
Genes & development 2004;18(16):1976-80.
2004: Juan-Jose Ventura; Norman J Kennedy; Richard A Flavell; Roger J Davis
JNK regulates autocrine expression of TGF-beta1.
Molecular cell 2004;15(2):269-78.
2004: Hongbo Chi; Binfeng Lu; Mutsuhiro Takekawa; Roger J Davis; Richard A Flavell
GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.
The EMBO journal 2004;23(7):1576-86.
2004: Stéphane Hunot; Miquel Vila; Peter Teismann; Roger J Davis; Etienne C Hirsch; Serge Przedborski; Pasko Rakic; Richard A Flavell
JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):665-70.
2003: Chia-Yi Kuan; Alan J Whitmarsh; Derek D Yang; Guanghong Liao; Aryn Schloemer; Chen Dong; Jue Bao; Kenneth J Banasiak; Gabriel G Haddad; Richard A Flavell; Roger J Davis; Pasko Rakic
A critical role of neural-specific JNK3 for ischemic apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15184-9.
2003: Thomas H Lee; Qiaojia Huang; Sarah Oikemus; Jennifer Shank; Juan-Jose Ventura; Nicole Cusson; Richard R Vaillancourt; Bing Su; Roger J Davis; Michelle A Kelliher
The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase.
Molecular and cellular biology 2003;23(22):8377-85.
2003: Nyaya Kelkar; Marie-Helene Delmotte; Claire R Weston; Tamera Barrett; Barbara J Sheppard; Richard A Flavell; Roger J Davis
Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3).
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9843-8.
2003: Deborah Brancho; Nobuyuki Tanaka; Anja Jaeschke; Juan-Jose Ventura; Nyaya Kelkar; Yoshinori Tanaka; Masanao Kyuuma; Toshikazu Takeshita; Richard A Flavell; Roger J Davis
Mechanism of p38 MAP kinase activation in vivo.
Genes & development 2003;17(16):1969-78.
2003: Masaya Tanno; Rekha Bassi; Diana A Gorog; Adrian T Saurin; Jie Jiang; Richard J Heads; Jody L Martin; Roger J Davis; Richard A Flavell; Michael S Marber
Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia.
Circulation research 2003;93(3):254-61.
2003: Xuchen Zhang; Peiying Shan; Jawed Alam; Roger J Davis; Richard A Flavell; Patty J Lee
Carbon monoxide modulates Fas/Fas ligand, caspases, and Bcl-2 family proteins via the p38alpha mitogen-activated protein kinase pathway during ischemia-reperfusion lung injury.
The Journal of biological chemistry 2003;278(24):22061-70.
2003: Jennifer A Lamb; Juan-Jose Ventura; Patricia Hess; Richard A Flavell; Roger J Davis
JunD mediates survival signaling by the JNK signal transduction pathway.
Molecular cell 2003;11(6):1479-89.
2003: Claire R Weston; Anthony Wong; J Perry Hall; Mary E P Goad; Richard A Flavell; Roger J Davis
JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure.
Genes & development 2003;17(10):1271-80.
2003: Norman J Kennedy; Roger J Davis
Role of JNK in tumor development.
Cell cycle (Georgetown, Tex.) 2003;2(3):199-201.
2003: Juan-Jose Ventura; Norman J Kennedy; Jennifer A Lamb; Richard A Flavell; Roger J Davis
c-Jun NH(2)-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor.
Molecular and cellular biology 2003;23(8):2871-82.
2003: Kui Lei; Roger J Davis
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2432-7.
2003: Norman J Kennedy; Hayla K Sluss; Stephen N Jones; Dafna Bar-Sagi; Richard A Flavell; Roger J Davis
Suppression of Ras-stimulated transformation by the JNK signal transduction pathway.
Genes & development 2003;17(5):629-37.
2003: Xuchen Zhang; Peiying Shan; Leo E Otterbein; Jawed Alam; Richard A Flavell; Roger J Davis; Augustine M K Choi; Patty J Lee
Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3.
The Journal of biological chemistry 2003;278(2):1248-58.
2002: Mohammad Ghahremani; Elizabeth Keramaris; Tanaya Shree; Zhengui Xia; Roger J Davis; Richard Flavell; ruth slack; David Park
Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage.
The Journal of biological chemistry 2002;277(38):35586-96.
2002: Patricia Hess; German Pihan; Charles L Sawyers; Richard A Flavell; Roger J Davis
Survival signaling mediated by c-Jun NH(2)-terminal kinase in transformed B lymphoblasts.
Nature genetics 2002;32(1):201-5.
2002: Nobuyuki Tanaka; Masahito Kamanaka; hervé enslen; Chen Dong; Mark Wysk; Roger J Davis; Richard A Flavell
Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis.
EMBO reports 2002;3(8):785-91.
2002: Sean A Diehl; Chi-Wing Chow; Linda Weiss; Alois Palmetshofer; Thomas Twardzik; Laura Rounds; Edgar Serfling; Roger J Davis; Juan Anguita; Mercedes Rincón
Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation.
The Journal of experimental medicine 2002;196(1):39-49.
2002: Kui Lei; Anjaruwee Nimnual; Wei-Xing Zong; Norman J Kennedy; Richard A Flavell; Craig Thompson; Dafna Bar-Sagi; Roger J Davis
The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase.
Molecular and cellular biology 2002;22(13):4929-42.
2002: Claire R Weston; David G Lambright; Roger J Davis
Signal transduction. MAP kinase signaling specificity.
Science (New York, N.Y.) 2002;296(5577):2345-7.
2002: Dietrich B Conze; Troy Krahl; Norman Kennedy; Linda Weiss; Joanne Lumsden; Patricia Hess; Richard A Flavell; Graham Le Gros; Roger J Davis; Mercedes Rincón
c-Jun NH(2)-terminal kinase (JNK)1 and JNK2 have distinct roles in CD8(+) T cell activation.
The Journal of experimental medicine 2002;195(7):811-23.
2002: Richard A Flavell; Chen Dong; Roger J Davis
Signaling and cell death in lymphocytes.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51(2):80-2.
2002: Claire R Weston; Roger J Davis
The JNK signal transduction pathway.
Current opinion in genetics & development 2002;12(1):14-21.
2002: J Perry Hall; Roger J Davis
Inhibition of the p38 pathway upregulates macrophage JNK and ERK activities, and the ERK, JNK, and p38 MAP kinase pathways are reprogrammed during differentiation of the murine myeloid M1 cell line.
Journal of cellular biochemistry 2002;86(1):1-11.
2002: J Perry Hall; Roger J Davis
Analysis of c-Jun N-terminal kinase regulation and function.
Methods in enzymology 2002;345():413-25.
2001: Alan J Whitmarsh; Chia-Yi Kuan; Norman J Kennedy; Nyaya Kelkar; Tarik F Haydar; John P Mordes; M Appel; A A Rossini; Stephen N Jones; Richard A Flavell; Pasko Rakic; Roger J Davis
Requirement of the JIP1 scaffold protein for stress-induced JNK activation.
Genes & development 2001;15(18):2421-32.
2001: William E Miller; Patricia McDonald; S F Cai; ME Field; Roger J Davis; Robert J Lefkowitz
Identification of a motif in the carboxyl terminus of beta -arrestin2 responsible for activation of JNK3.
The Journal of biological chemistry 2001;276(30):27770-7.
2001: Chen Dong; Roger J Davis; Richard A Flavell
Signaling by the JNK group of MAP kinases. c-jun N-terminal Kinase.
Journal of clinical immunology 2001;21(4):253-7.
2001: Claire R Weston; Roger J Davis
Signal transduction: signaling specificity- a complex affair.
Science (New York, N.Y.) 2001;292(5526):2439-40.
2001: C Tournier; Chen Dong; Tod K Turner; Stephen N Jones; Richard A Flavell; Roger J Davis
MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines.
Genes & development 2001;15(11):1419-26.
2001: G S De Zutter; Roger J Davis
Pro-apoptotic gene expression mediated by the p38 mitogen-activated protein kinase signal transduction pathway.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6168-73.
2001: B Lu; H Yu; Chi-Wing Chow; B Li; W Zheng; Roger J Davis; Richard A Flavell
GADD45gamma mediates the activation of the p38 and JNK MAP kinase pathways and cytokine production in effector TH1 cells.
Immunity 2001;14(5):583-90.
2001: Laxman Dass Gangwani; M Mikrut; S Theroux; M Sharma; Roger J Davis
Spinal muscular atrophy disrupts the interaction of ZPR1 with the SMN protein.
Nature cell biology 2001;3(4):376-83.
2001: Alan J Whitmarsh; Roger J Davis
Analyzing JNK and p38 mitogen-activated protein kinase activity.
Methods in enzymology 2001;332():319-36.
2000: J Perry Hall; Eric Merithew; Roger J Davis
c-Jun N-terminal kinase (JNK) repression during the inflammatory response? Just say NO.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14022-4.
2000: Patricia McDonald; Chi-Wing Chow; William E Miller; Stephane Laporte; ME Field; Fang-Tsyr Lin; Roger J Davis; Robert J Lefkowitz
Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3.
Science (New York, N.Y.) 2000;290(5496):1574-7.
2000: Roger J Davis
Signal transduction by the JNK group of MAP kinases.
Cell 2000;103(2):239-52.
2000: Stephanie L Constant; Chen Dong; Derek D Yang; Mark Wysk; Roger J Davis; Richard A Flavell
JNK1 is required for T cell-mediated immunity against Leishmania major infection.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2671-6.
2000: Chi-Wing Chow; Chen Dong; Richard A Flavell; Roger J Davis
c-Jun NH(2)-terminal kinase inhibits targeting of the protein phosphatase calcineurin to NFATc1.
Molecular and cellular biology 2000;20(14):5227-34.
2000: B Li; Haiyuan Yu; W Zheng; Reinhard E Voll; S Na; A W Roberts; D A Williams; Roger J Davis; Sankar Ghosh; Richard A Flavell
Role of the guanosine triphosphatase Rac2 in T helper 1 cell differentiation.
Science (New York, N.Y.) 2000;288(5474):2219-22.
2000: Dietrich B Conze; J Lumsden; hervé enslen; Roger J Davis; Graham Le Gros; Mercedes Rincón
Activation of p38 MAP kinase in T cells facilitates the immune response to the influenza virus.
Molecular immunology 2000;37(9):503-13.
2000: C Tournier; P Hess; Derek D Yang; Jianchao Xu; Tod K Turner; Anjaruwee Nimnual; Dafna Bar-Sagi; Stephen N Jones; Richard A Flavell; Roger J Davis
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway.
Science (New York, N.Y.) 2000;288(5467):870-4.
2000: Chen Dong; Derek D Yang; C Tournier; Alan J Whitmarsh; Jianchao Xu; Roger J Davis; Richard A Flavell
JNK is required for effector T-cell function but not for T-cell activation.
Nature 2000;405(6782):91-4.
2000: Mercedes Rincón; Dietrich B Conze; Linda Weiss; NL Diehl; Karen A Fortner; D Yang; Richard A Flavell; hervé enslen; Alan J Whitmarsh; Roger J Davis
Conference highlight: do T cells care about the mitogen-activated protein kinase signalling pathways?
Immunology and cell biology 2000;78(2):166-75.
2000: Leo E Otterbein; F H Bach; Jawed Alam; M Soares; H Tao Lu; Mark Wysk; Roger J Davis; Richard A Flavell; Augustine M K Choi
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway.
Nature medicine 2000;6(4):422-8.
2000: hervé enslen; Deborah Brancho; Roger J Davis
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms.
The EMBO journal 2000;19(6):1301-11.
2000: Nyaya Kelkar; S Gupta; M Dickens; Roger J Davis
Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.
Molecular and cellular biology 2000;20(3):1030-43.
2000: C Merritt; hervé enslen; NL Diehl; Dietrich B Conze; Roger J Davis; Mercedes Rincón
Activation of p38 mitogen-activated protein kinase in vivo selectively induces apoptosis of CD8(+) but not CD4(+) T cells.
Molecular and cellular biology 2000;20(3):936-46.
2000: NL Diehl; hervé enslen; Karen A Fortner; C Merritt; N Stetson; Colette Charland; Richard A Flavell; Roger J Davis; Mercedes Rincón
Activation of the p38 mitogen-activated protein kinase pathway arrests cell cycle progression and differentiation of immature thymocytes in vivo.
The Journal of experimental medicine 2000;191(2):321-34.
2000: Linda Weiss; Alan J Whitmarsh; Derek D Yang; Mercedes Rincón; Roger J Davis; Richard A Flavell
Regulation of c-Jun NH(2)-terminal kinase (Jnk) gene expression during T cell activation.
The Journal of experimental medicine 2000;191(1):139-46.
2000: Chi-Wing Chow; Roger J Davis
Integration of calcium and cyclic AMP signaling pathways by 14-3-3.
Molecular and cellular biology 2000;20(2):702-12.
1999: Jun Yasuda; Alan J Whitmarsh; J Cavanagh; M Sharma; Roger J Davis
The JIP group of mitogen-activated protein kinase scaffold proteins.
Molecular and cellular biology 1999;19(10):7245-54.
1999: Tae Ho Shin; Jun Yasuda; Christian E Rocheleau; Rueyling Lin; Martha Soto; Yanxia Bei; Roger J Davis; Craig C Mello
MOM-4, a MAP kinase kinase kinase-related protein, activates WRM-1/LIT-1 kinase to transduce anterior/posterior polarity signals in C. elegans.
Molecular cell 1999;4(2):275-80.
1999: Christian E Rocheleau; Jun Yasuda; Tae Ho Shin; Rueyling Lin; H Sawa; H Okano; James R Priess; Roger J Davis; Craig C Mello
WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans.
Cell 1999;97(6):717-26.
1999: Chia-Yi Kuan; Derek D Yang; D R Samanta Roy; Roger J Davis; Pasko Rakic; Richard A Flavell
The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.
Neuron 1999;22(4):667-76.
1999: HT Lu; Derek D Yang; Mark Wysk; Evelina Gatti; Ira Mellman; Roger J Davis; Richard A Flavell
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice.
The EMBO journal 1999;18(7):1845-57.
1999: Mark Wysk; Derek D Yang; HT Lu; Richard A Flavell; Roger J Davis
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3763-8.
1999: Chi-Wing Chow; M Rincón; Roger J Davis
Requirement for transcription factor NFAT in interleukin-2 expression.
Molecular and cellular biology 1999;19(3):2300-7.
1999: C Tournier; Alan J Whitmarsh; J Cavanagh; Tamera Barrett; Roger J Davis
The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases.
Molecular and cellular biology 1999;19(2):1569-81.
1999: B Li; C Tournier; Roger J Davis; Richard A Flavell
Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation.
The EMBO journal 1999;18(2):420-32.
1999: Richard A Flavell; B Li; Chen Dong; HT Lu; Derek D Yang; hervé enslen; C Tournier; Alan J Whitmarsh; Mark Wysk; Dietrich B Conze; M Rincon; Roger J Davis
Molecular basis of T-cell differentiation.
Cold Spring Harbor symposia on quantitative biology 1999;64():563-71.
1998: Laxman Dass Gangwani; M Mikrut; Z Galcheva-Gargova; Roger J Davis
Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells.
The Journal of cell biology 1998;143(6):1471-84.
1998: Chen Dong; Derek D Yang; Mark Wysk; Alan J Whitmarsh; Roger J Davis; Richard A Flavell
Defective T cell differentiation in the absence of Jnk1.
Science (New York, N.Y.) 1998;282(5396):2092-5.
1998: Mercedes Rincón; Alan J Whitmarsh; Derek D Yang; Linda Weiss; B Dérijard; P Jayaraj; Roger J Davis; Richard A Flavell
The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes.
The Journal of experimental medicine 1998;188(10):1817-30.
1998: Derek D Yang; Dietrich B Conze; Alan J Whitmarsh; T Barrett; Roger J Davis; Mercedes Rincón; Richard A Flavell
Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.
Immunity 1998;9(4):575-85.
1998: Z Galcheva-Gargova; Laxman Dass Gangwani; K N Konstantinov; M Mikrut; S J Theroux; T Enoch; Roger J Davis
The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells.
Molecular biology of the cell 1998;9(10):2963-71.
1998: Alan J Whitmarsh; J Cavanagh; C Tournier; Jun Yasuda; Roger J Davis
A mammalian scaffold complex that selectively mediates MAP kinase activation.
Science (New York, N.Y.) 1998;281(5383):1671-4.
1998: Richard A Flavell; Mercedes Rincón; W P Zheng; B Li; hervé enslen; J Raingeaud; Roger J Davis
The regulation of CD4 T cell differentiation.
European cytokine network 1998;9(3 Suppl):26-32.
1998: Z S Han; hervé enslen; Xiaodi Hu; X Meng; I H Wu; Tamera Barrett; Roger J Davis; Y Tony Ip
A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression.
Molecular and cellular biology 1998;18(6):3527-39.
1998: Mercedes Rincón; hervé enslen; J Raingeaud; M Recht; T Zapton; M S Su; L A Penix; Roger J Davis; Richard A Flavell
Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway.
The EMBO journal 1998;17(10):2817-29.
1998: J M Jacqué; A Mann; hervé enslen; Natalia Sharova; Beda Brichacek; Roger J Davis; Mario Stevenson
Modulation of HIV-1 infectivity by MAPK, a virion-associated kinase.
The EMBO journal 1998;17(9):2607-18.
1998: KK Elbirt; Alan J Whitmarsh; Roger J Davis; Herbert L Bonkovsky
Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases.
The Journal of biological chemistry 1998;273(15):8922-31.
1998: Y Tony Ip; Roger J Davis
Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development.
Current opinion in cell biology 1998;10(2):205-19.
1998: hervé enslen; J Raingeaud; Roger J Davis
Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6.
The Journal of biological chemistry 1998;273(3):1741-8.
1997: Chi-Wing Chow; M Rincón; J Cavanagh; M Dickens; Roger J Davis
Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway.
Science (New York, N.Y.) 1997;278(5343):1638-41.
1997: Derek D Yang; Chia-Yi Kuan; Alan J Whitmarsh; Mercedes Rincón; T S Zheng; Roger J Davis; Pasko Rakic; Richard A Flavell
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene.
Nature 1997;389(6653):865-70.
1997: Hayla K Sluss; Roger J Davis
Embryonic morphogenesis signaling pathway mediated by JNK targets the transcription factor JUN and the TGF-beta homologue decapentaplegic.
Journal of cellular biochemistry 1997;67(1):1-12.
1997: M Dickens; J S Rogers; J Cavanagh; Arthur B Raitano; Z Xia; J R Halpern; Michael E Greenberg; Charles L Sawyers; Roger J Davis
A cytoplasmic inhibitor of the JNK signal transduction pathway.
Science (New York, N.Y.) 1997;277(5326):693-6.
1997: C Tournier; Alan J Whitmarsh; J Cavanagh; Tamera Barrett; Roger J Davis
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7337-42.
1997: Alan J Whitmarsh; S H Yang; M S Su; Andrew D Sharrocks; Roger J Davis
Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors.
Molecular and cellular biology 1997;17(5):2360-71.
1997: D Yang; C Tournier; Mark Wysk; HT Lu; Jianchao Xu; Roger J Davis; Richard A Flavell
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3004-9.
1997: Mercedes Rincón; B Dérijard; Chi-Wing Chow; Roger J Davis; Richard A Flavell
Reprogramming the signalling requirement for AP-1 (activator protein-1) activation during differentiation of precursor CD4+ T-cells into effector Th1 and Th2 cells.
Genes and function 1997;1(1):51-68.
1996: C A Taglienti; Mark Wysk; Roger J Davis
Molecular cloning of the epidermal growth factor-stimulated protein kinase p56 KKIAMRE.
Oncogene 1996;13(12):2563-74.
1996: H K Sluss; Z Han; Tamera Barrett; D C Goberdhan; C Wilson; Roger J Davis; Y Tony Ip
A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila.
Genes & development 1996;10(21):2745-58.
1996: Alan J Whitmarsh; Roger J Davis
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.
Journal of molecular medicine (Berlin, Germany) 1996;74(10):589-607.
1996: P Shore; Alan J Whitmarsh; R Bhaskaran; Roger J Davis; Jonathan P Waltho; Andrew D Sharrocks
Determinants of DNA-binding specificity of ETS-domain transcription factors.
Molecular and cellular biology 1996;16(7):3338-49.
1996: Z Galcheva-Gargova; K N Konstantinov; I H Wu; F G Klier; Tamera Barrett; Roger J Davis
Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor.
Science (New York, N.Y.) 1996;272(5269):1797-802.
1996: S Gupta; Tamera Barrett; Alan J Whitmarsh; J Cavanagh; H K Sluss; B Dérijard; Roger J Davis
Selective interaction of JNK protein kinase isoforms with transcription factors.
The EMBO journal 1996;15(11):2760-70.
1996: Paul S. Shapiro; John N Evans; Roger J Davis; J A Posada
The seven-transmembrane-spanning receptors for endothelin and thrombin cause proliferation of airway smooth muscle cells and activation of the extracellular regulated kinase and c-Jun NH2-terminal kinase groups of mitogen-activated protein kinases.
The Journal of biological chemistry 1996;271(10):5750-4.
1996: J Raingeaud; Alan J Whitmarsh; Tamera Barrett; B Dérijard; Roger J Davis
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway.
Molecular and cellular biology 1996;16(3):1247-55.
1995: Z Galcheva-Gargova; S J Theroux; Roger J Davis
The epidermal growth factor receptor is covalently linked to ubiquitin.
Oncogene 1995;11(12):2649-55.
1995: Z Xia; M Dickens; J Raingeaud; Roger J Davis; Michael E Greenberg
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis.
Science (New York, N.Y.) 1995;270(5240):1326-31.
1995: Alan J Whitmarsh; P Shore; Andrew D Sharrocks; Roger J Davis
Integration of MAP kinase signal transduction pathways at the serum response element.
Science (New York, N.Y.) 1995;269(5222):403-7.
1995: J Raingeaud; S Gupta; J S Rogers; M Dickens; Jiahuai Han; R J Ulevitch; Roger J Davis
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine.
The Journal of biological chemistry 1995;270(13):7420-6.
1995: M Wartmann; D Campbell; A Subramanian; Sumner H Burstein; Roger J Davis
The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide.
FEBS letters 1995;359(2-3):133-6.
1995: B Dérijard; J Raingeaud; Tamera Barrett; I H Wu; Jiahuai Han; R J Ulevitch; Roger J Davis
Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms.
Science (New York, N.Y.) 1995;267(5198):682-5.
1995: S Gupta; D Campbell; B Dérijard; Roger J Davis
Transcription factor ATF2 regulation by the JNK signal transduction pathway.
Science (New York, N.Y.) 1995;267(5196):389-93.
1994: Audrey Minden; A Lin; M McMahon; C Lange-Carter; B Dérijard; Roger J Davis; Gary L Johnson; Michael Karin
Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK.
Science (New York, N.Y.) 1994;266(5191):1719-23.
1994: H K Sluss; Tamera Barrett; B Dérijard; Roger J Davis
Signal transduction by tumor necrosis factor mediated by JNK protein kinases.
Molecular and cellular biology 1994;14(12):8376-84.
1994: Roger J Davis
MAPKs: new JNK expands the group.
Trends in biochemical sciences 1994;19(11):470-3.
1994: S Gupta; Roger J Davis
MAP kinase binds to the NH2-terminal activation domain of c-Myc.
FEBS letters 1994;353(3):281-5.
1994: Z Galcheva-Gargova; B Dérijard; I H Wu; Roger J Davis
An osmosensing signal transduction pathway in mammalian cells.
Science (New York, N.Y.) 1994;265(5173):806-8.
1994: B Dérijard; Masahiko Hibi; I H Wu; Tamera Barrett; B Su; T Deng; Michael Karin; Roger J Davis
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.
Cell 1994;76(6):1025-37.
1994: M Wartmann; Roger J Davis
The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex.
The Journal of biological chemistry 1994;269(9):6695-701.
1994: L Li; M Wysk; F A Gonzalez; Roger J Davis
Genomic loci of human mitogen-activated protein kinases.
Oncogene 1994;9(2):647-9.
1993: F A Gonzalez; A Seth; D L Raden; D S Bowman; Fred S Fay; Roger J Davis
Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus.
The Journal of cell biology 1993;122(5):1089-101.
1993: Roger J Davis
The mitogen-activated protein kinase signal transduction pathway.
The Journal of biological chemistry 1993;268(20):14553-6.
1993: A Seth; S Gupta; Roger J Davis
Cell cycle regulation of the c-Myc transcriptional activation domain.
Molecular and cellular biology 1993;13(7):4125-36.
1993: S Gupta; A Seth; Roger J Davis
Transactivation of gene expression by Myc is inhibited by mutation at the phosphorylation sites Thr-58 and Ser-62.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3216-20.
1993: C A Taglienti-Sian; B Banner; Roger J Davis; Harriet L Robinson
Induction of renal adenocarcinoma by a nonmutated erbB oncogene.
Journal of virology 1993;67(2):1132-6.
1993: E Selva; D L Raden; Roger J Davis
Mitogen-activated protein kinase stimulation by a tyrosine kinase-negative epidermal growth factor receptor.
The Journal of biological chemistry 1993;268(3):2250-4.
1993: Roger J Davis
Sphingolipid regulation of the epidermal growth factor receptor.
Advances in lipid research 1993;25():131-45.
1992: A Seth; F A Gonzalez; S Gupta; D L Raden; Roger J Davis
Signal transduction within the nucleus by mitogen-activated protein kinase.
The Journal of biological chemistry 1992;267(34):24796-804.
1992: S J Theroux; K Stanley; D A Campbell; Roger J Davis
Mutational removal of the major site of serine phosphorylation of the epidermal growth factor receptor causes potentiation of signal transduction: role of receptor down-regulation.
Molecular endocrinology (Baltimore, Md.) 1992;6(11):1849-57.
1992: S J Theroux; D A Latour; K Stanley; D L Raden; Roger J Davis
Signal transduction by the epidermal growth factor receptor is attenuated by a COOH-terminal domain serine phosphorylation site.
The Journal of biological chemistry 1992;267(23):16620-6.
1992: F A Gonzalez; D L Raden; M R Rigby; Roger J Davis
Heterogeneous expression of four MAP kinase isoforms in human tissues.
FEBS letters 1992;304(2-3):170-8.
1992: N Nair; Roger J Davis; Harriet L Robinson
Protein tyrosine kinase activities of the epidermal growth factor receptor and ErbB proteins: correlation of oncogenic activation with altered kinetics.
Molecular and cellular biology 1992;12(5):2010-6.
1992: S J Theroux; C Taglienti-Sian; N Nair; J L Countaway; Harriet L Robinson; Roger J Davis
Increased oncogenic potential of ErbB is associated with the loss of a COOH-terminal domain serine phosphorylation site.
The Journal of biological chemistry 1992;267(12):7967-70.
1992: S J Theroux; Roger J Davis
Rapid screening of cloned DNA fragments for specific mutations.
Nucleic acids research 1992;20(4):915.
1992: J L Countaway; Angus Nairn; Roger J Davis
Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase.
The Journal of biological chemistry 1992;267(2):1129-40.
1991: A Seth; E Alvarez; S Gupta; Roger J Davis
A phosphorylation site located in the NH2-terminal domain of c-Myc increases transactivation of gene expression.
The Journal of biological chemistry 1991;266(35):23521-4.
1991: F A Gonzalez; D L Raden; Roger J Davis
Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases.
The Journal of biological chemistry 1991;266(33):22159-63.
1991: N Gironès; E Alverez; A Seth; I M Lin; D A Latour; Roger J Davis
Mutational analysis of the cytoplasmic tail of the human transferrin receptor. Identification of a sub-domain that is required for rapid endocytosis.
The Journal of biological chemistry 1991;266(28):19006-12.
1991: E Alvarez; I C Northwood; F A Gonzalez; D A Latour; A Seth; C Abate; T Curran; Roger J Davis
Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase.
The Journal of biological chemistry 1991;266(23):15277-85.
1991: I C Northwood; F A Gonzalez; M Wartmann; D L Raden; Roger J Davis
Isolation and characterization of two growth factor-stimulated protein kinases that phosphorylate the epidermal growth factor receptor at threonine 669.
The Journal of biological chemistry 1991;266(23):15266-76.
1991: S Bowen; K Stanley; E Selva; Roger J Davis
Constitutive phosphorylation of the epidermal growth factor receptor blocks mitogenic signal transduction.
The Journal of biological chemistry 1991;266(2):1162-9.
1990: E Alvarez; N Gironès; Roger J Davis
Inhibition of the receptor-mediated endocytosis of diferric transferrin is associated with the covalent modification of the transferrin receptor with palmitic acid.
The Journal of biological chemistry 1990;265(27):16644-55.
1990: I C Northwood; Roger J Davis
Signal transduction by the epidermal growth factor receptor after functional desensitization of the receptor tyrosine protein kinase activity.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(16):6107-11.
1990: F M Weis; Roger J Davis
Regulation of epidermal growth factor receptor signal transduction. Role of gangliosides.
The Journal of biological chemistry 1990;265(20):12059-66.
1990: E Alvarez; N Gironès; Roger J Davis
A point mutation in the cytoplasmic domain of the transferrin receptor inhibits endocytosis.
The Biochemical journal 1990;267(1):31-5.
1990: J L Countaway; P McQuilkin; N Gironès; Roger J Davis
Multisite phosphorylation of the epidermal growth factor receptor. Use of site-directed mutagenesis to examine the role of serine/threonine phosphorylation.
The Journal of biological chemistry 1990;265(6):3407-16.
1989: N Gironès; Roger J Davis
Comparison of the kinetics of cycling of the transferrin receptor in the presence or absence of bound diferric transferrin.
The Biochemical journal 1989;264(1):35-46.
1989: J L Countaway; N Gironès; Roger J Davis
Reconstitution of epidermal growth factor receptor transmodulation by platelet-derived growth factor in Chinese hamster ovary cells.
The Journal of biological chemistry 1989;264(23):13642-7.
1989: E Alvarez; N Gironès; Roger J Davis
Intermolecular disulfide bonds are not required for the expression of the dimeric state and functional activity of the transferrin receptor.
The EMBO journal 1989;8(8):2231-40.
1989: J L Countaway; I C Northwood; Roger J Davis
Mechanism of phosphorylation of the epidermal growth factor receptor at threonine 669.
The Journal of biological chemistry 1989;264(18):10828-35.
1989: I C Northwood; Roger J Davis
Protein kinase C inhibition of the epidermal growth factor receptor tyrosine protein kinase activity is independent of the oligomeric state of the receptor.
The Journal of biological chemistry 1989;264(10):5746-50.
1988: Roger J Davis
Independent mechanisms account for the regulation by protein kinase C of the epidermal growth factor receptor affinity and tyrosine-protein kinase activity.
The Journal of biological chemistry 1988;263(19):9462-9.
1988: I C Northwood; Roger J Davis
Activation of the epidermal growth factor receptor tyrosine protein kinase in the absence of receptor oligomerization.
The Journal of biological chemistry 1988;263(16):7450-3.
1988: Roger J Davis; N Gironès; M Faucher
Two alternative mechanisms control the interconversion of functional states of the epidermal growth factor receptor.
The Journal of biological chemistry 1988;263(11):5373-9.
1988: M Faucher; N Gironès; Yusuf A Hannun; R M Bell; Roger J Davis
Regulation of the epidermal growth factor receptor phosphorylation state by sphingosine in A431 human epidermoid carcinoma cells.
The Journal of biological chemistry 1988;263(11):5319-27.
1987: Roger J Davis; H Meisner
Regulation of transferrin receptor cycling by protein kinase C is independent of receptor phosphorylation at serine 24 in Swiss 3T3 fibroblasts.
The Journal of biological chemistry 1987;262(33):16041-7.
1987: Roger J Davis; M Faucher; L K Racaniello; Anthony Carruthers; Michael P Czech
Insulin-like growth factor I and epidermal growth factor regulate the expression of transferrin receptors at the cell surface by distinct mechanisms.
The Journal of biological chemistry 1987;262(27):13126-34.
1987: Roger J Davis; M P Czech
Regulatory control of the epidermal growth factor receptor tyrosine kinase.
Haematology and blood transfusion 1987;31():228-32.