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Hind Al-Qassab

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C Gelegen; C B Hyde; Elaine E Irvine; A B Leiter; S E Sloan; Dominic J Withers; K Chandarana; Agharul I Choudhury; Marc Claret; I M Evans; Hind Al-Qassab; Fabrizio Andreelli; Rachel L Batterham
Regulation of hindbrain Pyy expression by acute food deprivation, prolonged caloric restriction, and weight loss surgery in mice.
Derek A Costello; peter giese; Elaine E Irvine; Hind Al-Qassab; Agharul I Choudhury; Marc Claret; Florian Plattner; Dominic J Withers; Paola Pedarzani
Brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity.
Elaine E Irvine; Laura Drinkwater; Kasia Radwanska; Hind Al-Qassab; Mark A Smith; Melissa O'Brien; Catherine Kielar; Agharul I Choudhury; Stefan Krauss; Jonathan D Cooper; Dominic J Withers; peter giese
Insulin receptor substrate 2 is a negative regulator of memory formation.

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All Publications

2012: C Gelegen; C B Hyde; Elaine E Irvine; A B Leiter; S E Sloan; Dominic J Withers; K Chandarana; Agharul I Choudhury; Marc Claret; I M Evans; Hind Al-Qassab; Fabrizio Andreelli; Rachel L Batterham
Regulation of hindbrain Pyy expression by acute food deprivation, prolonged caloric restriction, and weight loss surgery in mice.
American journal of physiology. Endocrinology and metabolism 2012;303(5):E659-68.
2012: Derek A Costello; peter giese; Elaine E Irvine; Hind Al-Qassab; Agharul I Choudhury; Marc Claret; Florian Plattner; Dominic J Withers; Paola Pedarzani
Brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity.
PloS one 2012;7(2):e31124.
2011: Elaine E Irvine; Laura Drinkwater; Kasia Radwanska; Hind Al-Qassab; Mark A Smith; Melissa O'Brien; Catherine Kielar; Agharul I Choudhury; Stefan Krauss; Jonathan D Cooper; Dominic J Withers; peter giese
Insulin receptor substrate 2 is a negative regulator of memory formation.
Learning & memory (Cold Spring Harbor, N.Y.) 2011;18(6):375-83.
2011: Marc Claret; Mark A Smith; Claude Knauf; Hind Al-Qassab; Angela Woods; Amanda Heslegrave; Kaisa Piipari; Julian J Emmanuel; André Colom; Philippe Valet; Patrice D Cani; Ghazala Begum; Anne White; Phillip Mucket; Marco Peters; Keiko Mizuno; Rachel L Batterham; peter giese; Alan Ashworth; Remy Burcelin; Michael L Ashford; David Carling; Dominic J Withers
Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice.
Diabetes 2011;60(3):735-45.
2010: Craig Beall; Kaisa Piipari; Hind Al-Qassab; Mark A Smith; Nadeene Parker; David Carling; Benoit Viollet; Dominic J Withers; Michael L J Ashford
Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.
The Biochemical journal 2010;429(2):323-33.
2009: Hind Al-Qassab; Mark A Smith; Elaine E Irvine; Julie Guillermet-Guibert; Marc Claret; Agharul I Choudhury; Colin Selman; Kaisa Piipari; Melanie Clements; Steven Lingard; Keval Chandarana; Jimmy D Bell; Gregory S Barsh; Andrew J H Smith; Rachel L Batterham; Michael L J Ashford; Bart Vanhaesebroeck; Dominic J Withers
Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons.
Cell metabolism 2009;10(5):343-54.
2009: Colin Selman; Jennifer M A Tullet; Daniela Wieser; Elaine Irvine; Steven J Lingard; Agharul I Choudhury; Marc Claret; Hind Al-Qassab; Danielle Carmignac; Faruk Ramadani; Angela Woods; Iain C A Robinson; Eugene Schuster; Rachel L Batterham; Sara C Kozma; George Thomas; David Carling; Klaus Okkenhaug; Janet M Thornton; Linda Partridge; David Gems; Dominic J Withers
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.
Science (New York, N.Y.) 2009;326(5949):140-4.
2009: Richard Killick; Georgie Scales; Karelle Leroy; Mirsada Causevic; Claudie Hooper; Elaine E Irvine; Agharul I Choudhury; Laura Drinkwater; Fiona Kerr; Hind Al-Qassab; John Stephenson; Zehra Yilmaz; peter giese; Jean-Pierre Brion; Dominic J Withers; Simon Lovestone
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice.
Biochemical and biophysical research communications 2009;386(1):257-62.
2008: Colin Selman; Steven J Lingard; Agharul I Choudhury; Rachel L Batterham; Marc Claret; Melanie Clements; Faruk Ramadani; Klaus Okkenhaug; Eugene Schuster; Eric Blanc; Matthew D W Piper; Hind Al-Qassab; John R Speakman; Danielle Carmignac; Iain C A F Robinson; Janet M Thornton; David Gems; Linda Partridge; Dominic J Withers
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(3):807-18.
2007: Marc Claret; Mark A Smith; Rachel L Batterham; Colin Selman; Agharul I Choudhury; Lee G D Fryer; Melanie Clements; Hind Al-Qassab; Helen Heffron; Allison W Xu; John R Speakman; Gregory S Barsh; Benoit Viollet; Sophie Vaulont; Michael L J Ashford; David Carling; Dominic J Withers
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons.
The Journal of clinical investigation 2007;117(8):2325-36.
2007: Irina Neganova; Hind Al-Qassab; Helen Heffron; Colin Selman; Agharul I Choudhury; Steven J Lingard; Ivan Diakonov; Michael Patterson; Mohammad A Ghatei; Stephen R Bloom; Stephen Franks; Ilpo Huhtaniemi; Kate Hardy; Dominic J Withers
Role of central nervous system and ovarian insulin receptor substrate 2 signaling in female reproductive function in the mouse.
Biology of reproduction 2007;76(6):1045-53.
2007: Mark A Smith; Kazunari Hisadome; Hind Al-Qassab; Helen Heffron; Dominic J Withers; Michael L J Ashford
Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances.
The Journal of physiology 2007;578(Pt 2):425-38.
2005: Agharul I Choudhury; Helen Heffron; Mark A Smith; Hind Al-Qassab; Allison W Xu; Colin Selman; Marcus Simmgen; Melanie Clements; Marc Claret; Gavin MacColl; David Bedford; Kazunari Hisadome; Ivan Diakonov; Vazira Moosajee; Jimmy D Bell; John R Speakman; Rachel L Batterham; Gregory S Barsh; Michael L J Ashford; Dominic J Withers
The role of insulin receptor substrate 2 in hypothalamic and beta cell function.
The Journal of clinical investigation 2005;115(4):940-50.