FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

CJ Carrera

Research Profile

Chemicals & Drugs

Disorders

Anatomy

Physiology

Cell Survival

Co-author Network

Publications

TOP 3
M Schmid; M Sen; MD Rosenbach; CJ Carrera; H Friedman; Dennis A Carson
A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer.
Davide Genini; S Adachi; Q Chao; David Rose; CJ Carrera; Howard B Cottam; Dennis A Carson; Lorenzo Leoni
Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria.
Hsiencheng Shih; L Deng; CJ Carrera; S Adachi; Howard B Cottam; Dennis A Carson
Rational design, synthesis and structure-activity relationships of antitumor (E)-2-benzylidene-1-tetralones and (E)-2-benzylidene-1-indanones.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of CJ Carrera (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2000: M Schmid; M Sen; MD Rosenbach; CJ Carrera; H Friedman; Dennis A Carson
A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer.
Oncogene 2000;19(50):5747-54.
2000: Davide Genini; S Adachi; Q Chao; David Rose; CJ Carrera; Howard B Cottam; Dennis A Carson; Lorenzo Leoni
Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria.
Blood 2000;96(10):3537-43.
2000: Hsiencheng Shih; L Deng; CJ Carrera; S Adachi; Howard B Cottam; Dennis A Carson
Rational design, synthesis and structure-activity relationships of antitumor (E)-2-benzylidene-1-tetralones and (E)-2-benzylidene-1-indanones.
Bioorganic & medicinal chemistry letters 2000;10(5):487-90.
2000: Lorenzo Leoni; Ernest Hamel; Davide Genini; Hsiencheng Shih; CJ Carrera; Howard B Cottam; Dennis A Carson
Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells.
Journal of the National Cancer Institute 2000;92(3):217-24.
2000: Davide Genini; I Budihardjo; W Plunkett; X Wang; CJ Carrera; Howard B Cottam; Dennis A Carson; Lorenzo Leoni
Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway.
The Journal of biological chemistry 2000;275(1):29-34.
1998: M Schmid; Denise M Malicki; T Nobori; MD Rosenbach; K Campbell; Dennis A Carson; CJ Carrera
Homozygous deletions of methylthioadenosine phosphorylase (MTAP) are more frequent than p16INK4A (CDKN2) homozygous deletions in primary non-small cell lung cancers (NSCLC).
Oncogene 1998;17(20):2669-75.
1998: Lorenzo Leoni; Q Chao; Howard B Cottam; Davide Genini; MD Rosenbach; CJ Carrera; I Budihardjo; X Wang; Dennis A Carson
Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9567-71.
1998: Y Hori; H Hori; Y Yamada; CJ Carrera; M Tomonaga; S Kamihira; Dennis A Carson; T Nobori
The methylthioadenosine phosphorylase gene is frequently co-deleted with the p16INK4a gene in acute type adult T-cell leukemia.
International journal of cancer. Journal international du cancer 1998;75(1):51-6.
1996: H Hori; Phuoc Tran; CJ Carrera; Y Hori; M D Rosenbach; Dennis A Carson; T Nobori
Methylthioadenosine phosphorylase cDNA transfection alters sensitivity to depletion of purine and methionine in A549 lung cancer cells.
Cancer research 1996;56(24):5653-8.
1995: B Eibschutz; S M Baird; M H Weisman; D G Amox; M Spellman; D Piacquadio; CJ Carrera; Dennis A Carson
Oral 2-chlorodeoxyadenosine in psoriatic arthritis. A preliminary report.
Arthritis and rheumatism 1995;38(11):1604-9.
1994: CJ Carrera; Alan Saven; Lawrence D Piro
Purine metabolism of lymphocytes. Targets for chemotherapy drug development.
Hematology/oncology clinics of North America 1994;8(2):357-81.
1994: E Beutler; James A Koziol; R McMillan; Jack C Sipe; John S Romine; CJ Carrera
Marrow suppression produced by repeated doses of cladribine.
Acta haematologica 1994;91(1):10-5.
1993: Alan Saven; H Kawasaki; CJ Carrera; T Waltz; B Copeland; J Zyroff; M Kosty; D A Carson; E Beutler; Lawrence D Piro
2-Chlorodeoxyadenosine dose escalation in nonhematologic malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993;11(4):671-8.
1993: H Kawasaki; CJ Carrera; Lawrence D Piro; Alan Saven; Thomas Kipps; Dennis A Carson
Relationship of deoxycytidine kinase and cytoplasmic 5'-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine.
Blood 1993;81(3):597-601.
1993: Alan Saven; Lawrence D Piro; CJ Carrera; D A Carson; E Beutler
Hairy cell leukemia: new understanding of biology and treatment.
Cancer treatment and research 1993;64():15-34.
1992: H Kawasaki; CJ Carrera; Dennis A Carson
Quantitative immunoassay of human deoxycytidine kinase in malignant cells.
Analytical biochemistry 1992;207(1):193-6.
1992: Alan Saven; CJ Carrera; D A Carson; E Beutler; Lawrence D Piro
2-Chlorodeoxyadenosine: an active agent in the treatment of cutaneous T-cell lymphoma.
Blood 1992;80(3):587-92.
1992: Dennis A Carson; D B Wasson; L M Esparza; CJ Carrera; Thomas Kipps; Howard B Cottam
Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2970-4.
1992: A C Kay; Alan Saven; CJ Carrera; D A Carson; D Thurston; E Beutler; Lawrence D Piro
2-Chlorodeoxyadenosine treatment of low-grade lymphomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(3):371-7.
1991: C Terai; D B Wasson; CJ Carrera; Dennis A Carson
Dependence of cell survival on DNA repair in human mononuclear phagocytes.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(12):4302-6.
1991: Dennis A Carson; CJ Carrera; D B Wasson; T Iizasa
Deoxyadenosine-resistant human T lymphoblasts with elevated 5'-nucleotidase activity.
Biochimica et biophysica acta 1991;1091(1):22-8.
1991: CJ Carrera; Lawrence D Piro; Alan Saven; E Beutler; C Terai; Dennis A Carson
2-Chlorodeoxyadenosine chemotherapy triggers programmed cell death in normal and malignant lymphocytes.
Advances in experimental medicine and biology 1991;309A():15-8.
1990: CJ Carrera; C Terai; Martin Lotz; J G Curd; Lawrence D Piro; E Beutler; Dennis A Carson
Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. A novel approach to immunosuppressive therapy.
The Journal of clinical investigation 1990;86(5):1480-8.
1990: Dennis A Carson; CJ Carrera
Immunodeficiency secondary to adenosine deaminase deficiency and purine nucleoside phosphorylation deficiency.
Seminars in hematology 1990;27(3):260-9.
1990: Lawrence D Piro; CJ Carrera; Dennis A Carson; E Beutler
Lasting remissions in hairy-cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine.
The New England journal of medicine 1990;322(16):1117-21.
1989: Dennis A Carson; T Haertle; CJ Carrera; Erik Willis; D B Wasson; D D Richman
2-halo-2',3'-dideoxyadenosines: metabolically stable dideoxynucleosides with activity against the human immunodeficiency virus (HIV).
Advances in experimental medicine and biology 1989;253B():395-8.
1989: Dennis A Carson; Lawrence D Piro; D B Wasson; CJ Carrera; E Beutler
Activity of 2-chloro-2'-deoxyadenosine in chronic lymphocytic leukemia, hairy cell leukemia, and autoimmune hemolytic anemia.
Advances in experimental medicine and biology 1989;253A():427-31.
1989: CJ Carrera; H Yamanaka; Lawrence D Piro; M Lotz; Dennis A Carson
Profound toxicity of deoxyadenosine and 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo.
Advances in experimental medicine and biology 1989;253B():219-25.
1988: Lawrence D Piro; CJ Carrera; E Beutler; Dennis A Carson
2-Chlorodeoxyadenosine: an effective new agent for the treatment of chronic lymphocytic leukemia.
Blood 1988;72(3):1069-73.
1988: T Haertle; CJ Carrera; D B Wasson; L C Sowers; D D Richman; Dennis A Carson
Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2',3'-dideoxyadenosine derivatives.
The Journal of biological chemistry 1988;263(12):5870-5.
1988: Dennis A Carson; T Nobori; E O Kajander; CJ Carrera; M Kubota; H Yamanaka
Methylthioadenosine (MeSAdo) phosphorylase deficiency in malignancy.
Advances in experimental medicine and biology 1988;250():179-85.
1988: Dennis A Carson; CJ Carrera; D B Wasson; H Yamanaka
Programmed cell death and adenine deoxynucleotide metabolism in human lymphocytes.
Advances in enzyme regulation 1988;27():395-404.
1986: E O Kajander; M Kubota; CJ Carrera; J A Montgomery; D A Carson
Resistance to multiple adenine nucleoside and methionine analogues in mutant murine lymphoma cells with enlarged S-adenosylmethionine pools.
Cancer research 1986;46(6):2866-70.
1986: D A Carson; S Seto; D B Wasson; CJ Carrera
DNA strand breaks, NAD metabolism, and programmed cell death.
Experimental cell research 1986;164(2):273-81.
1986: S Seto; CJ Carrera; D B Wasson; D A Carson
Inhibition of DNA repair by deoxyadenosine in resting human lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(8):2839-43.
1986: CJ Carrera; Erik Willis; R R Chilcote; M Kubota; Dennis A Carson
5'-deoxy-5'-methylthioadenosine phosphorylase deficiency in leukemia: genetics and biochemical aspects.
Advances in experimental medicine and biology 1986;195 Pt B():643-50.
1986: Dennis A Carson; CJ Carrera; M Kubota; D B Wasson; T Iizasa
Genetic analysis of deoxyadenosine toxicity in dividing human lymphoblasts.
Advances in experimental medicine and biology 1986;195 Pt B():207-11.
1986: S Seto; CJ Carrera; D B Wasson; D A Carson
Biochemical basis for deoxyadenosine and 2-chlorodeoxyadenosine toxicity to resting human lymphocytes.
Advances in experimental medicine and biology 1986;195 Pt B():577-82.
1985: S Seto; CJ Carrera; M Kubota; D B Wasson; D A Carson
Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes.
The Journal of clinical investigation 1985;75(2):377-83.
1985: Dennis A Carson; T Iizasa; S Seto; CJ Carrera; M Kubota; Erik Willis; D B Wasson; O Kajander
Metabolic basis for immune dysfunction in adenosine deaminase deficiency.
Annals of the New York Academy of Sciences 1985;451():34-41.
1984: M Kubota; CJ Carrera; D B Wasson; D A Carson
Deoxynucleoside overproduction in deoxyadenosine-resistant, adenosine deaminase-deficient human histiocytic lymphoma cells.
Biochimica et biophysica acta 1984;804(1):37-43.