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Lionel Mourey

Research Profile

Procedures

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Chemicals & Drugs

Phenomena

Living Beings

Mycobacterium tuberculosis

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Publications

TOP 3
Cécile Leblanc; Lionel Mourey; Thomas Prudhomme; Aurélie Ray; Guillaume Tabouret; Sophie Burbaud; Stéphanie Cabantous; Christophe Guilhot; Christian Chalut
4'-Phosphopantetheinyl transferase PptT, a new drug target required for Mycobacterium tuberculosis growth and persistence in vivo.
Elise Champion; Karine Descroix; Frédéric Guérin; Pierre Monsan; Sandrine Morel; Claire Moulis; Lionel Mourey; Laurence A Mulard; Magali Remaud-Siméon; Thu Hoai Tran; Samuel Tranier; Sophie Barbe; Isabelle André
Applying pairwise combinations of amino acid mutations for sorting out highly efficient glucosylation tools for chemo-enzymatic synthesis of bacterial oligosaccharides.
Fabien Bergeret; Christian Chalut; Mamadou Daffé; Sabine Gavalda; Christophe Guilhot; Wladimir Malaga; Lionel Mourey; Jean-Denis Pedelacq; Annaïk Quémard; Cécile Bon
Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase Pks13.

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All Publications

2012: Cécile Leblanc; Lionel Mourey; Thomas Prudhomme; Aurélie Ray; Guillaume Tabouret; Sophie Burbaud; Stéphanie Cabantous; Christophe Guilhot; Christian Chalut
4'-Phosphopantetheinyl transferase PptT, a new drug target required for Mycobacterium tuberculosis growth and persistence in vivo.
PLoS pathogens 2012;8(12):e1003097.
2012: Elise Champion; Karine Descroix; Frédéric Guérin; Pierre Monsan; Sandrine Morel; Claire Moulis; Lionel Mourey; Laurence A Mulard; Magali Remaud-Siméon; Thu Hoai Tran; Samuel Tranier; Sophie Barbe; Isabelle André
Applying pairwise combinations of amino acid mutations for sorting out highly efficient glucosylation tools for chemo-enzymatic synthesis of bacterial oligosaccharides.
Journal of the American Chemical Society 2012;134(45):18677-88.
2012: Fabien Bergeret; Christian Chalut; Mamadou Daffé; Sabine Gavalda; Christophe Guilhot; Wladimir Malaga; Lionel Mourey; Jean-Denis Pedelacq; Annaïk Quémard; Cécile Bon
Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase Pks13.
The Journal of biological chemistry 2012;287(40):33675-90.
2012: Romain Galy; Daniel Keller; Lionel Mourey; Gilles Prévost; Fabien Bergeret; laurent maveyraud
Crystallization and preliminary crystallographic studies of both components of the staphylococcal LukE-LukD leukotoxin.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 6):663-7.
2012: Yoann Brison; Yannick Malbert; Pierre Monsan; Sandrine Morel; Lionel Mourey; Tjaard Pijning; Gabrielle Potocki-Véronèse; Magali Remaud-Siméon; Samuel Tranier; Émeline Fabre; Bauke W Dijkstra
Functional and structural characterization of α-(1->2) branching sucrase derived from DSR-E glucansucrase.
The Journal of biological chemistry 2012;287(11):7915-24.
2012: Frédéric Guérin; David Guieysse; Valérie Guillet; Pierre Monsan; Lionel Mourey; Sandra Pizzut-Serin; Gabrielle Potocki-Véronèse; Magali Remaud-Siméon; Isabelle André; Sophie Barbe; Samuel Tranier
Structural investigation of the thermostability and product specificity of amylosucrase from the bacterium Deinococcus geothermalis.
The Journal of biological chemistry 2012;287(9):6642-54.
2011: Justin M Kollman; Andreas Merdes; Lionel Mourey; David A Agard
Microtubule nucleation by γ-tubulin complexes.
Nature reviews. Molecular cell biology 2011;12(11):709-21.
2011: Luis F Garcia-Alles; Martine GILLERON; Julie Guiard; Albert J R Heck; Emilie Huc; Jin S Im; Sylviane Julien; Buko Lindner; laurent maveyraud; Lucia Mori; Lionel Mourey; Steven A Porcelli; Jacques Prandi; Germain Puzo; Sebastiano Sansano; Cees Versluis; Thérèse Brando; Anthony Collmann; Henri de la Salle; Gennaro De Libero
Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(43):17755-60.
2011: Jean-Denis Pedelacq; Thomas C Terwilliger; Carolyn Bell; Stephanie Cabantous; Alexandre Faille; Natasha Friedland; Pawel Listwan; Meghan Lockard; Brian L Mark; Lionel Mourey; Hau B Nguyen; Geoffrey S Waldo
Experimental mapping of soluble protein domains using a hierarchical approach.
Nucleic acids research 2011;39(18):e125.
2011: Luis F Garcia-Alles; Gaelle Giacometti; Martine GILLERON; Julie Guiard; Daniel Hanau; Albert J R Heck; laurent maveyraud; Lucia Mori; Lionel Mourey; Jacques Prandi; Germain Puzo; Samuel Tranier; Cees Versluis; Gennaro De Libero; Diane de Paepe; Henri de la Salle
Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(32):13230-5.
2011: Valérie Guillet; M Knibiehler; Justin M Kollman; Andreas Merdes; David A Agard; Cécile Bon; Cécile Chemin; Lynn Gregory-Pauron; Brigitte Raynaud-Messina; Marie-Hélène Remy; Lionel Mourey
Crystal structure of γ-tubulin complex protein GCP4 provides insight into microtubule nucleation.
Nature structural & molecular biology 2011;18(8):915-9.
2010: Florence Bordes; Sophie Barbe; Pierre Escalier; Lionel Mourey; Isabelle André; Alain Marty; Samuel Tranier
Exploring the conformational states and rearrangements of Yarrowia lipolytica Lipase.
Biophysical journal 2010;99(7):2225-34.
2009: Julien Vaubourgeix; Fabienne Bardou; Fanny Boissier; Sylviane Julien; Patricia Constant; Olivier Ploux; Mamadou Daffé; Annaïk Quémard; Lionel Mourey
S-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases.
The Journal of biological chemistry 2009;284(29):19321-30.
2009: Julie Guiard; Anthony Collmann; Luis Fernando Garcia-Alles; Lionel Mourey; Thérèse Brando; Lucia Mori; Martine GILLERON; Jacques Prandi; Gennaro De Libero; Germain Puzo
Fatty acyl structures of mycobacterium tuberculosis sulfoglycolipid govern T cell response.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):7030-7.
2009: Mathieu Léger; Sabine Gavalda; Valérie Guillet; Benoît van der Rest; Nawel Slama; Henri Montrozier; Lionel Mourey; Annaïk Quémard; Mamadou Daffé; Hedia Marrakchi
The dual function of the Mycobacterium tuberculosis FadD32 required for mycolic acid biosynthesis.
Chemistry & biology 2009;16(5):510-9.
2009: laurent maveyraud; Hideaki Niwa; Valérie Guillet; Dmitri I Svergun; Peter V Konarev; Rex A Palmer; Willy J Peumans; Pierre Rougé; Els J M Van Damme; Colin D Reynolds; Lionel Mourey
Structural basis for sugar recognition, including the Tn carcinoma antigen, by the lectin SNA-II from Sambucus nigra.
Proteins 2009;75(1):89-103.
2008: Pierre Roblin; Valérie Guillet; Olivier Joubert; Daniel Keller; Monique Erard; laurent maveyraud; Gilles Prévost; Lionel Mourey
A covalent S-F heterodimer of leucotoxin reveals molecular plasticity of beta-barrel pore-forming toxins.
Proteins 2008;71(1):485-96.
2008: Damien Bessière; Chrystelle Lacroix; Sébastien Campagne; Vincent Ecochard; Valérie Guillet; Lionel Mourey; Frédéric Lopez; Jerzy Czaplicki; Pascal Demange; Alain Milon; Jean-Philippe Girard; Virginie Gervais
Structure-function analysis of the THAP zinc finger of THAP1, a large C2CH DNA-binding module linked to Rb/E2F pathways.
The Journal of biological chemistry 2008;283(7):4352-63.
2007: Robert Alazard; Lionel Mourey; Christine Ebel; Peter V Konarev; Maxim V Petoukhov; Dmitri I Svergun; Monique Erard
Fine-tuning of intrinsic N-Oct-3 POU domain allostery by regulatory DNA targets.
Nucleic acids research 2007;35(13):4420-32.
2007: Olivier Joubert; Joëlle Voegelin; Valérie Guillet; Samuel Tranier; Sandra Werner; Didier A Colin; Daniel Keller; Henri Monteil; Lionel Mourey; Mauro Dalla Serra; Gilles Prévost
Distinction between pore assembly by staphylococcal alpha-toxin versus leukotoxins.
Journal of biomedicine & biotechnology 2007;2007(1):25935.
2006: Luis F Garcia-Alles; Kees Versluis; laurent maveyraud; Ana Tesouro Vallina; Sebastiano Sansano; Nana Fatimath Bello; Hans-Jürgen Gober; Valérie Guillet; Henri de la Salle; Germain Puzo; Lucia Mori; albert heck; Gennaro De Libero; Lionel Mourey
Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b.
The EMBO journal 2006;25(15):3684-92.
2006: Olivier Joubert; Gabriella Viero; Daniel Keller; Eric Martinez; Didier A Colin; Henri Monteil; Lionel Mourey; Mauro Dalla Serra; Gilles Prévost
Engineered covalent leucotoxin heterodimers form functional pores: insights into S-F interactions.
The Biochemical journal 2006;396(2):381-9.
2006: Fanny Boissier; Fabienne Bardou; Valérie Guillet; Sandrine Uttenweiler; Mamadou Daffé; Annaïk Quémard; Lionel Mourey
Further insight into S-adenosylmethionine-dependent methyltransferases: structural characterization of Hma, an enzyme essential for the biosynthesis of oxygenated mycolic acids in Mycobacterium tuberculosis.
The Journal of biological chemistry 2006;281(7):4434-45.
2005: Henri de la Salle; Sabrina Mariotti; Catherine Angenieux; Martine GILLERON; Luis F Garcia-Alles; Dag Malm; Thomas Berg; Samantha Paoletti; Blandine Maître; Lionel Mourey; Jean Salamero; Jean-Pierre Cazenave; Daniel Hanau; Lucia Mori; Germain Puzo; Gennaro De Libero
Assistance of microbial glycolipid antigen processing by CD1e.
Science (New York, N.Y.) 2005;310(5752):1321-4.
2004: Romain Veyron-Churlet; Olivier Guerrini; Lionel Mourey; Mamadou Daffé; Didier Zerbib
Protein-protein interactions within the Fatty Acid Synthase-II system of Mycobacterium tuberculosis are essential for mycobacterial viability.
Molecular microbiology 2004;54(5):1161-72.
2004: Valérie Guillet; Pierre Roblin; Sandra Werner; Manuela Coraiola; Gianfranco Menestrina; Henri Monteil; Gilles Prévost; Lionel Mourey
Crystal structure of leucotoxin S component: new insight into the Staphylococcal beta-barrel pore-forming toxins.
The Journal of biological chemistry 2004;279(39):41028-37.
2004: sylvie monferran; Catherine Muller; Lionel Mourey; Philippe Frit; bernard salles
The Membrane-associated form of the DNA repair protein Ku is involved in cell adhesion to fibronectin.
Journal of molecular biology 2004;337(3):503-11.
2004: Valérie Guillet; Daniel Keller; Gilles Prévost; Lionel Mourey
Crystallization and preliminary crystallographic data of a leucotoxin S component from Staphylococcus aureus.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 2):310-3.
2001: Lionel Mourey; Sandra Da Re; Jean-Denis Pédelacq; Tatiana Tolstykh; C Faurie; Valérie Guillet; Jeffry B Stock; Jean-Pierre Samama
Crystal structure of the CheA histidine phosphotransfer domain that mediates response regulator phosphorylation in bacterial chemotaxis.
The Journal of biological chemistry 2001;276(33):31074-82.
2001: M Foussard; Stéphanie Cabantous; Jean-Denis Pédelacq; Valérie Guillet; Samuel Tranier; Lionel Mourey; Catherine Birck; Jean-Pierre Samama
The molecular puzzle of two-component signaling cascades.
Microbes and infection / Institut Pasteur 2001;3(5):417-24.
2001: Gilles Prévost; Lionel Mourey; Didier A Colin; Gianfranco Menestrina
Staphylococcal pore-forming toxins.
Current topics in microbiology and immunology 2001;257():53-83.
2001: Patrice Gouet; N Chinardet; M Welch; Valérie Guillet; Stéphanie Cabantous; Catherine Birck; Lionel Mourey; Jean-Pierre Samama
Further insights into the mechanism of function of the response regulator CheY from crystallographic studies of the CheY--CheA(124--257) complex.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 1):44-51.
2000: Dasantila Golemi; laurent maveyraud; Akihiro Ishiwata; Samuel Tranier; K Miyashita; T Nagase; I Massova; Lionel Mourey; Jean-Pierre Samama; Shahriar Mobashery
6-(hydroxyalkyl)penicillanates as probes for mechanisms of beta-lactamases.
The Journal of antibiotics 2000;53(10):1022-7.
2000: Jean-Denis Pédelacq; Gilles Prévost; Henri Monteil; Lionel Mourey; Jean-Pierre Samama
Crystal structure of the F component of the Panton-Valentine leucocidin.
International journal of medical microbiology : IJMM 2000;290(4-5):395-401.
1999: Patrice Gouet; B Fabry; Valérie Guillet; Catherine Birck; Lionel Mourey; D Kahn; Jean-Pierre Samama
Structural transitions in the FixJ receiver domain.
Structure (London, England : 1993) 1999;7(12):1517-26.
1999: Catherine Birck; Lionel Mourey; Patrice Gouet; B Fabry; J Schumacher; P Rousseau; D Kahn; Jean-Pierre Samama
Conformational changes induced by phosphorylation of the FixJ receiver domain.
Structure (London, England : 1993) 1999;7(12):1505-15.
1999: Lamine Baba-Moussa; Sandra Werner; Didier A Colin; Lionel Mourey; Jean-Denis Pédelacq; Jean-Pierre Samama; A Sanni; Henri Monteil; Gilles Prévost
Discoupling the Ca(2+)-activation from the pore-forming function of the bi-component Panton-Valentine leucocidin in human PMNs.
FEBS letters 1999;461(3):280-6.
1999: Lionel Mourey; Lakshmi P Kotra; J Bellettini; A Bulychev; M O'Brien; M J Miller; Shahriar Mobashery; Jean-Pierre Samama
Inhibition of the broad spectrum nonmetallocarbapenamase of class A (NMC-A) beta-lactamase from Enterobacter cloacae by monocyclic beta-lactams.
The Journal of biological chemistry 1999;274(36):25260-5.
1999: Jean-Denis Pédelacq; laurent maveyraud; Gilles Prévost; Lamine Baba-Moussa; A González; E Courcelle; W Shepard; Henri Monteil; Jean-Pierre Samama; Lionel Mourey
The structure of a Staphylococcus aureus leucocidin component (LukF-PV) reveals the fold of the water-soluble species of a family of transmembrane pore-forming toxins.
Structure (London, England : 1993) 1999;7(3):277-87.
1998: P Swarén; laurent maveyraud; X Raquet; Stéphanie Cabantous; C Duez; Jean-Denis Pédelacq; S Mariotte-Boyer; Lionel Mourey; R Labia; Marie-Hélène Nicolas-Chanoine; patrice nordmann; J M Frère; Jean-Pierre Samama
X-ray analysis of the NMC-A beta-lactamase at 1.64-A resolution, a class A carbapenemase with broad substrate specificity.
The Journal of biological chemistry 1998;273(41):26714-21.
1998: Lionel Mourey; Jean-Denis Pédelacq; Catherine Birck; C Fabre; Pierre Rougé; Jean-Pierre Samama
Crystal structure of the arcelin-1 dimer from Phaseolus vulgaris at 1.9-A resolution.
The Journal of biological chemistry 1998;273(21):12914-22.
1998: Robert Alazard; Christine Ebel; V Venien-Bryan; Lionel Mourey; Jean-Pierre Samama; Michael Chandler
Oligomeric structure of the repressor of the bacteriophage Mu early operon.
European journal of biochemistry / FEBS 1998;252(3):408-15.
1998: C Fabre; H Causse; Lionel Mourey; J Koninkx; Michel Rivière; H Hendriks; Germain Puzo; Jean-Pierre Samama; Pierre Rougé
Characterization and sugar-binding properties of arcelin-1, an insecticidal lectin-like protein isolated from kidney bean (Phaseolus vulgaris L. cv. RAZ-2) seeds.
The Biochemical journal 1998;329 ( Pt 3)():551-60.
1998: M Welch; N Chinardet; Lionel Mourey; Catherine Birck; Jean-Pierre Samama
Structure of the CheY-binding domain of histidine kinase CheA in complex with CheY.
Nature structural biology 1998;5(1):25-9.
1997: Lionel Mourey; Jean-Denis Pédelacq; C Fabre; H Causse; Pierre Rougé; Jean-Pierre Samama
Small-angle X-ray scattering and crystallographic studies of arcelin-1: an insecticidal lectin-like glycoprotein from Phaseolus vulgaris L.
Proteins 1997;29(4):433-42.
1997: Jean Cavarelli; Gilles Prévost; William Bourguet; L Moulinier; B Chevrier; B Delagoutte; A Bilwes; Lionel Mourey; S Rifai; Yves Piémont; Dino Moras
The structure of Staphylococcus aureus epidermolytic toxin A, an atypic serine protease, at 1.7 A resolution.
Structure (London, England : 1993) 1997;5(6):813-24.
1996: laurent maveyraud; Isabelle Saves; O Burlet-Schiltz; P Swarén; Jean-Michel Masson; M Delaire; Lionel Mourey; Jean-Claude Promé; Jean-Pierre Samama
Structural basis of extended spectrum TEM beta-lactamases. Crystallographic, kinetic, and mass spectrometric investigations of enzyme mutants.
The Journal of biological chemistry 1996;271(18):10482-9.
1995: P Swarén; laurent maveyraud; V Guillet; Jean-Michel Masson; Lionel Mourey; Jean-Pierre Samama
Electrostatic analysis of TEM1 beta-lactamase: effect of substrate binding, steep potential gradients and consequences of site-directed mutations.
Structure (London, England : 1993) 1995;3(6):603-13.
1993: C Jelsch; Lionel Mourey; Jean-Michel Masson; Jean-Pierre Samama
Crystal structure of Escherichia coli TEM1 beta-lactamase at 1.8 A resolution.
Proteins 1993;16(4):364-83.
1993: Lionel Mourey; Jean-Pierre Samama; M Delarue; M Petitou; J Choay; Dino Moras
Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution.
Journal of molecular biology 1993;232(1):223-41.
1990: Lionel Mourey; Jean-Pierre Samama; M Delarue; J Choay; J C Lormeau; M Petitou; Dino Moras
Antithrombin III: structural and functional aspects.
Biochimie 1990;72(8):599-608.
1989: Jean-Pierre Samama; M Delarue; Lionel Mourey; J Choay; Dino Moras
Crystallization and preliminary crystallographic data for bovine antithrombin III.
Journal of molecular biology 1989;210(4):877-9.