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Youyang Zhao

Research Profile

Living Beings

Physiology

Chemicals & Drugs

Anatomy

Disorders

Hypertension, Pulmonary

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Publications

TOP 3
Yidan D Zhao; Lei Cai; Dave L Geenen; Franz Hofmann; Xiaojia Huang; Muhammad Kamran Mirza; Jason X-J Yuan; Youyang Zhao
Protein kinase G-I deficiency induces pulmonary hypertension through Rho A/Rho kinase activation.
Yuru Liu; Guy R Adami; Vladimir V Kalinichenko; Viswanathan Natarajan; Srikanth Pendyala; Ruxana T Sadikot; Youyang Zhao; Asrar B Malik
FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas aeruginosa.
Mohammad Rizwan Siddiqui; Yulia Komarova; Stephen M Vogel; Xiao-Pei Gao; Marcelo Bonini; Johnson Rajasingh; Youyang Zhao; Viktor Brovkovych; Asrar B Malik
Caveolin-1-eNOS signaling promotes p190RhoGAP-A nitration and endothelial permeability.

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All Publications

2012: Yidan D Zhao; Lei Cai; Dave L Geenen; Franz Hofmann; Xiaojia Huang; Muhammad Kamran Mirza; Jason X-J Yuan; Youyang Zhao
Protein kinase G-I deficiency induces pulmonary hypertension through Rho A/Rho kinase activation.
The American journal of pathology 2012;180(6):2268-75.
2011: Yuru Liu; Guy R Adami; Vladimir V Kalinichenko; Viswanathan Natarajan; Srikanth Pendyala; Ruxana T Sadikot; Youyang Zhao; Asrar B Malik
FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas aeruginosa.
The Journal of experimental medicine 2011;208(7):1473-84.
2011: Mohammad Rizwan Siddiqui; Yulia Komarova; Stephen M Vogel; Xiao-Pei Gao; Marcelo Bonini; Johnson Rajasingh; Youyang Zhao; Viktor Brovkovych; Asrar B Malik
Caveolin-1-eNOS signaling promotes p190RhoGAP-A nitration and endothelial permeability.
The Journal of cell biology 2011;193(5):841-50.
2010: Muhammad Kamran Mirza; Ying Sun; Yidan D Zhao; Hari-Hara S K Potula; Randall S Frey; Stephen M Vogel; Asrar B Malik; Youyang Zhao
FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of beta-catenin expression.
The Journal of experimental medicine 2010;207(8):1675-85.
2010: Anke Di; Takeshi Kawamura; Xiao-Pei Gao; Hai Yang Tang; Evgeny Berdyshev; Stephen M Vogel; Youyang Zhao; Tiffany Sharma; Kurt Bachmaier; Jingsong Xu; Asrar B Malik
A novel function of sphingosine kinase 1 suppression of JNK activity in preventing inflammation and injury.
The Journal of biological chemistry 2010;285(21):15848-57.
2010: Muhammad Kamran Mirza; Jason X-J Yuan; Xiao-Pei Gao; Sean Garrean; Viktor Brovkovych; Asrar B Malik; Chinnaswamy Tiruppathi; Youyang Zhao
Caveolin-1 deficiency dampens Toll-like receptor 4 signaling through eNOS activation.
The American journal of pathology 2010;176(5):2344-51.
2010: Ling Xue; Leslie Chiang; Bo He; Youyang Zhao; Astar Winoto
FoxM1, a forkhead transcription factor is a master cell cycle regulator for mouse mature T cells but not double positive thymocytes.
PloS one 2010;5(2):e9229.
2010: Yidan D Zhao; Hiroshi Ohkawara; Stephen M Vogel; Asrar B Malik; Youyang Zhao
Bone marrow-derived progenitor cells prevent thrombin-induced increase in lung vascular permeability.
American journal of physiology. Lung cellular and molecular physiology 2010;298(1):L36-44.
2009: Youyang Zhao; Asrar B Malik
A novel insight into the mechanism of pulmonary hypertension involving caveolin-1 deficiency and endothelial nitric oxide synthase activation.
Trends in cardiovascular medicine 2009;19(7):238-42.
2009: Yidan D Zhao; Hiroshi Ohkawara; Jalees Rehman; Kishore K Wary; Stephen M Vogel; Richard D Minshall; Youyang Zhao; Asrar B Malik
Bone marrow progenitor cells induce endothelial adherens junction integrity by sphingosine-1-phosphate-mediated Rac1 and Cdc42 signaling.
Circulation research 2009;105(7):696-704, 8 p following 704.
2009: Youyang Zhao; Yidan D Zhao; Muhammad Kamran Mirza; Julia H Huang; Hari-Hara S K Potula; Stephen M Vogel; Viktor Brovkovych; Jason X-J Yuan; John Wharton; Asrar B Malik
Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration.
The Journal of clinical investigation 2009;119(7):2009-18.
2008: Jingsong Xu; Xiao-Pei Gao; Ramaswamy Ramchandran; Youyang Zhao; Stephen M Vogel; Asrar B Malik
Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating beta2 integrins.
Nature immunology 2008;9(8):880-6.
2007: Sneha Ramakrishna; Il-Man Kim; Vladimir Petrovic; Dmitriy Malin; I-Ching Wang; Tanya V Kalin; Lucille Meliton; Youyang Zhao; Timothy Ackerson; Yimin Qin; Asrar B Malik; Robert H Costa; Vladimir V. Kalinichenko
Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box M1 transcription factor.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(4):1000-13.
2006: Sean Garrean; Xiao-Pei Gao; Viktor Brovkovych; Jun Shimizu; Youyang Zhao; Stephen M Vogel; Asrar B Malik
Caveolin-1 regulates NF-kappaB activation and lung inflammatory response to sepsis induced by lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4853-60.
2006: Youyang Zhao; Xiao-Pei Gao; Yidan D Zhao; Muhammad Kamran Mirza; Randall S Frey; Vladimir V. Kalinichenko; I-Ching Wang; Robert H Costa; Asrar B Malik
Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury.
The Journal of clinical investigation 2006;116(9):2333-43.
2004: Tricia A Babcock; william helton; Khandaker N Anwar; Youyang Zhao; N Joseph Espat
Synergistic anti-inflammatory activity of omega-3 lipid and rofecoxib pretreatment on macrophage proinflammatory cytokine production occurs via divergent NF-kappaB activation.
JPEN. Journal of parenteral and enteral nutrition 2004;28(4):232-9; discussion 239-40.
2002: Youyang Zhao; Yang Liu; Radu V Stan; Lian Fan; Yusu Gu; Nancy Dalton; Pao-Hsien Chu; Kirk Peterson; John Ross; Kenneth R Chien
Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(17):11375-80.
2002: Steven A Crone; Youyang Zhao; Lian Fan; Yusu Gu; Susumu Minamisawa; Yang Liu; Kirk L Peterson; Ju Chen; Ronald Kahn; Gianluigi Condorelli; John Ross; Kenneth R Chien; Kuo-Fee Lee
ErbB2 is essential in the prevention of dilated cardiomyopathy.
Nature medicine 2002;8(5):459-65.
2000: I Kubota; X Han; DJ Opel; Youyang Zhao; R Baliga; P Huang; M C Fishman; R P Shannon; Thomas Michel; Ralph A Kelly
Increased susceptibility to development of triggered activity in myocytes from mice with targeted disruption of endothelial nitric oxide synthase.
Journal of molecular and cellular cardiology 2000;32(7):1239-48.
1999: R R Baliga; David R Pimental; Youyang Zhao; W W Simmons; M A Marchionni; Douglas B Sawyer; Ralph A Kelly
NRG-1-induced cardiomyocyte hypertrophy. Role of PI-3-kinase, p70(S6K), and MEK-MAPK-RSK.
The American journal of physiology 1999;277(5 Pt 2):H2026-37.
1999: Olivier Feron; Youyang Zhao; Ralph A Kelly
The ins and outs of caveolar signaling. m2 muscarinic cholinergic receptors and eNOS activation versus neuregulin and ErbB4 signaling in cardiac myocytes.
Annals of the New York Academy of Sciences 1999;874():11-9.
1999: Youyang Zhao; Olivier Feron; Chantal Dessy; X Han; M A Marchionni; Ralph A Kelly
Neuregulin signaling in the heart. Dynamic targeting of erbB4 to caveolar microdomains in cardiac myocytes.
Circulation research 1999;84(12):1380-7.
1998: X Han; I Kubota; Olivier Feron; DJ Opel; MA Arstall; Youyang Zhao; P Huang; M C Fishman; Thomas Michel; Ralph A Kelly
Muscarinic cholinergic regulation of cardiac myocyte ICa-L is absent in mice with targeted disruption of endothelial nitric oxide synthase.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6510-5.
1998: Youyang Zhao; D R Sawyer; R R Baliga; DJ Opel; X Han; M A Marchionni; Ralph A Kelly
Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes.
The Journal of biological chemistry 1998;273(17):10261-9.
1997: X Han; L Kobzik; Youyang Zhao; DJ Opel; W D Liu; Ralph A Kelly; T W Smith
Nitric oxide regulation of atrioventricular node excitability.
The Canadian journal of cardiology 1997;13(12):1191-201.